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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Post-Head Injury Coma
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Accession:DOID:9003416 term browser browse the term
Definition:Prolonged unconsciousness from which the individual cannot be aroused, associated with traumatic injuries to the BRAIN. This may be defined as unconsciousness persisting for 6 hours or longer. Coma results from injury to both cerebral hemispheres or the RETICULAR FORMATION of the BRAIN STEM. Contributing mechanisms include DIFFUSE AXONAL INJURY and BRAIN EDEMA. (From J Neurotrauma 1997 Oct;14(10):699-713)
Synonyms:exact_synonym: Coma, Post-Traumatic, Prolonged;   Post-Concussive Coma;   Post-Concussive Comas;   Post-Head Injury Comas;   Post-Trauma Coma;   Post-Trauma Comas;   Post-Traumatic Coma;   Traumatic Coma
 primary_id: MESH:D020207
 alt_id: RDO:0007348
For additional species annotation, visit the Alliance of Genome Resources.


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Post-Head Injury Coma term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trh thyrotropin releasing hormone ISO CTD Direct Evidence: therapeutic CTD PMID:8690305 NCBI chr 4:124,110,716...124,113,242
Ensembl chr 4:124,110,716...124,113,242
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Term paths to the root
Path 1
Term Annotations click to browse term
  disease 16023
    Wounds and Injuries 835
      Nervous System Trauma 531
        Craniocerebral Trauma 336
          Post-Head Injury Coma 1
Path 2
Term Annotations click to browse term
  disease 16023
    disease of anatomical entity 15278
      nervous system disease 10897
        central nervous system disease 9045
          brain disease 8370
            disease of mental health 6047
              cognitive disorder 1914
                Consciousness Disorders 26
                  Unconsciousness 26
                    Coma 11
                      Post-Head Injury Coma 1
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.