ONTOLOGY REPORT - ANNOTATIONS


Term:Hyperpigmentation
go back to main search page
Accession:DOID:9003984 term browser browse the term
Definition:Excessive pigmentation of the skin, usually as a result of increased epidermal or dermal melanin pigmentation, hypermelanosis. Hyperpigmentation can be localized or generalized. The condition may arise from exposure to light, chemicals or other substances, or from a primary metabolic imbalance.
Synonyms:exact_synonym: Hypermelanoses;   Hypermelanosis
 primary_id: MESH:D017495;   RDO:0000461
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants       view all columns           Sort by:
 
Hyperpigmentation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AHR aryl hydrocarbon receptor JBrowse link 14 31,743,704 31,793,484 RGD:9068941
G RPL27A ribosomal protein L27a JBrowse link 21 32,099,792 32,102,761 RGD:9068941
G SLC29A3 solute carrier family 29 member 3 JBrowse link 4 22,094,899 22,135,066 RGD:9068941
acanthosis nigricans term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G FGFR3 fibroblast growth factor receptor 3 JBrowse link 3 62,309,128 62,318,932 RGD:9068941
G PRMT7 protein arginine methyltransferase 7 JBrowse link 5 81,172,085 81,216,708 RGD:9068941
G SLC2A3 solute carrier family 2 member 3 JBrowse link 27 37,297,932 37,309,604 RGD:9068941
G TBC1D4 TBC1 domain family member 4 JBrowse link 22 29,109,079 29,175,357 RGD:9068941
Beare-Stevenson cutis gyrata syndrome term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G FGFR2 fibroblast growth factor receptor 2 JBrowse link 28 31,303,882 31,411,015 RGD:7240710
RGD:9068941
Crouzon syndrome-acanthosis nigricans syndrome term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G FGFR3 fibroblast growth factor receptor 3 JBrowse link 3 62,309,128 62,318,932 RGD:7240710
RGD:9068941
Dermatopathia Pigmentosa Reticularis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G KRT14 keratin 14 JBrowse link 9 21,190,672 21,195,060 RGD:7240710
RGD:9068941
Dowling-Degos disease term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ADAM10 ADAM metallopeptidase domain 10 JBrowse link 30 23,605,724 23,732,038 RGD:9068941
G KRT81 keratin 81 JBrowse link 27 2,776,693 2,782,016 RGD:7240710
RGD:9068941
G POFUT1 protein O-fucosyltransferase 1 JBrowse link 24 21,608,905 21,636,084 RGD:9068941
G POGLUT1 protein O-glucosyltransferase 1 JBrowse link 33 23,122,682 23,150,863 RGD:9068941
Dowling-Degos Disease 2 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G POFUT1 protein O-fucosyltransferase 1 JBrowse link 24 21,608,905 21,636,084 RGD:7240710
RGD:9068941
Dowling-Degos Disease 4 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G POGLUT1 protein O-glucosyltransferase 1 JBrowse link 33 23,122,682 23,150,863 RGD:7240710
RGD:9068941
Hyperpigmentation with or without Hypopigmentation, Familial Progressive term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G KITLG KIT ligand JBrowse link 15 29,591,068 29,671,985 RGD:7240710
RGD:9068941
Insulin-Resistant Diabetes Mellitus, with Acanthosis Nigricans term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G INSR insulin receptor JBrowse link 20 52,017,261 52,136,061 RGD:7240710
RGD:9068941
Lentigo term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G HGF hepatocyte growth factor JBrowse link 18 21,329,688 21,410,257 RGD:9068941
LEOPARD syndrome term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BRAF B-Raf proto-oncogene, serine/threonine kinase JBrowse link 16 8,222,909 8,318,179 RGD:9068941
G EPHA2 EPH receptor A2 JBrowse link 2 81,534,130 81,561,722 RGD:9068941
G PPP1R13L protein phosphatase 1 regulatory subunit 13 like JBrowse link 1 110,149,393 110,166,029 RGD:9068941
G PTEN phosphatase and tensin homolog JBrowse link 26 37,853,148 37,913,176 RGD:9068941
G PTPN11 protein tyrosine phosphatase non-receptor type 11 JBrowse link 26 9,989,218 10,072,245 RGD:9068941
G RAF1 Raf-1 proto-oncogene, serine/threonine kinase JBrowse link 20 5,892,839 5,972,672 RGD:9068941
G RPL6 ribosomal protein L6 JBrowse link 26 9,970,416 9,975,897 RGD:9068941
LEOPARD Syndrome 1 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PTPN11 protein tyrosine phosphatase non-receptor type 11 JBrowse link 26 9,989,218 10,072,245 RGD:7240710
RGD:9068941
LEOPARD Syndrome 2 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G RAF1 Raf-1 proto-oncogene, serine/threonine kinase JBrowse link 20 5,892,839 5,972,672 RGD:7240710
RGD:9068941
LEOPARD Syndrome 3 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BRAF B-Raf proto-oncogene, serine/threonine kinase JBrowse link 16 8,222,909 8,318,179 RGD:7240710
RGD:9068941
Melanosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ALDH2 aldehyde dehydrogenase 2 family member JBrowse link 26 9,319,109 9,361,021 RGD:9068941
Neurocutaneous Melanosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G NRAS NRAS proto-oncogene, GTPase JBrowse link 17 52,411,733 52,418,788 RGD:7240710
RGD:9068941
Peutz-Jeghers syndrome term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ABCA7 ATP binding cassette subfamily A member 7 JBrowse link 20 57,668,371 57,684,111 RGD:9068941
G ARHGAP45 Rho GTPase activating protein 45 JBrowse link 20 57,656,693 57,668,324 RGD:9068941
G ARID3A AT-rich interaction domain 3A JBrowse link 20 57,724,747 57,746,637 RGD:9068941
G CBARP CACN subunit beta associated regulatory protein JBrowse link 20 57,554,162 57,559,126 RGD:9068941
G CFD complement factor D JBrowse link 20 57,785,297 57,787,773 RGD:9068941
G CNN2 calponin 2 JBrowse link 20 57,684,959 57,691,621 RGD:9068941
G ELANE elastase, neutrophil expressed JBrowse link 20 57,789,044 57,790,932 RGD:9068941
G GRIN3B glutamate ionotropic receptor NMDA type subunit 3B JBrowse link 20 57,703,569 57,710,119 RGD:9068941
G KISS1R KISS1 receptor JBrowse link 20 57,756,046 57,758,940 RGD:9068941
G MED16 mediator complex subunit 16 JBrowse link 20 57,771,543 57,782,839 RGD:9068941
G POLR2E RNA polymerase II subunit E JBrowse link 20 57,649,836 57,653,661 RGD:9068941
G R3HDM4 R3H domain containing 4 JBrowse link 20 57,761,100 57,769,656 RGD:9068941
G SBNO2 strawberry notch homolog 2 JBrowse link 20 57,592,901 57,640,047 RGD:9068941
G STK11 serine/threonine kinase 11 JBrowse link 20 57,558,966 57,579,163 RGD:7240710
RGD:9068941
G TMEM259 transmembrane protein 259 JBrowse link 20 57,695,004 57,703,650 RGD:9068941
G WDR18 WD repeat domain 18 JBrowse link 20 57,712,854 57,717,988 RGD:9068941
reticulate acropigmentation of Kitamura term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ADAM10 ADAM metallopeptidase domain 10 JBrowse link 30 23,605,724 23,732,038 RGD:7240710
RGD:9068941
G KRT81 keratin 81 JBrowse link 27 2,776,693 2,782,016 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 11301
    sensory system disease 3908
      skin disease 2058
        pigmentation disease 185
          Hyperpigmentation 41
            Ataxia-Telangiectasia with Generalized Skin Pigmentation and Early Death 0
            Dermatopathia Pigmentosa Reticularis 1
            Dowling-Degos disease + 4
            Hyperkeratosis-Hyperpigmentation Syndrome 0
            Hyperpigmentation of Fuldauer and Kuijpers 0
            Hyperpigmentation, Familial Progressive + 1
            Melanosis + 32
            Melanosis, Universal 0
            Multiform Ventricular Extrasystoles with Short Stature, Hyperpigmentation and Microcephaly 0
            Patterson Pseudoleprechaunism Syndrome 0
            hyperpigmentation of eyelid 0
Path 2
Term Annotations click to browse term
  disease 11301
    disease of anatomical entity 10812
      nervous system disease 8297
        sensory system disease 3908
          skin disease 2058
            pigmentation disease 185
              Hyperpigmentation 41
                Ataxia-Telangiectasia with Generalized Skin Pigmentation and Early Death 0
                Dermatopathia Pigmentosa Reticularis 1
                Dowling-Degos disease + 4
                Hyperkeratosis-Hyperpigmentation Syndrome 0
                Hyperpigmentation of Fuldauer and Kuijpers 0
                Hyperpigmentation, Familial Progressive + 1
                Melanosis + 32
                Melanosis, Universal 0
                Multiform Ventricular Extrasystoles with Short Stature, Hyperpigmentation and Microcephaly 0
                Patterson Pseudoleprechaunism Syndrome 0
                hyperpigmentation of eyelid 0
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.