ONTOLOGY REPORT - ANNOTATIONS


Term:Hyperpigmentation
go back to main search page
Accession:DOID:9003984 term browser browse the term
Definition:Excessive pigmentation of the skin, usually as a result of increased epidermal or dermal melanin pigmentation, hypermelanosis. Hyperpigmentation can be localized or generalized. The condition may arise from exposure to light, chemicals or other substances, or from a primary metabolic imbalance.
Synonyms:exact_synonym: Hypermelanoses;   Hypermelanosis
 primary_id: MESH:D017495;   RDO:0000461
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants       view all columns           Sort by:
 
Hyperpigmentation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ahr aryl hydrocarbon receptor JBrowse link NW_004936546 3,737,908 3,783,492 RGD:9068941
G Rpl27a ribosomal protein L27a JBrowse link NW_004936528 9,343,620 9,348,935 RGD:9068941
G Slc29a3 solute carrier family 29 member 3 JBrowse link NW_004936521 7,417,914 7,452,695 RGD:9068941
acanthosis nigricans term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fgfr3 fibroblast growth factor receptor 3 JBrowse link NW_004936477 21,591,772 21,606,289 RGD:9068941
G Prmt7 protein arginine methyltransferase 7 JBrowse link NW_004936475 18,632,022 18,667,515 RGD:9068941
G Tbc1d4 TBC1 domain family member 4 JBrowse link NW_004936511 5,789,683 5,858,930 RGD:9068941
Beare-Stevenson cutis gyrata syndrome term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fgfr2 fibroblast growth factor receptor 2 JBrowse link NW_004936486 10,506,680 10,606,272 RGD:7240710
RGD:9068941
Crouzon syndrome-acanthosis nigricans syndrome term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fgfr3 fibroblast growth factor receptor 3 JBrowse link NW_004936477 21,591,772 21,606,289 RGD:7240710
RGD:9068941
Dowling-Degos disease term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adam10 ADAM metallopeptidase domain 10 JBrowse link NW_004936471 19,760,709 19,911,759 RGD:9068941
G Krt5 keratin 5 JBrowse link NW_004936512 9,923,593 9,929,517 RGD:7240710
RGD:9068941
G Pofut1 protein O-fucosyltransferase 1 JBrowse link NW_004936485 19,111,704 19,137,689 RGD:9068941
G Poglut1 protein O-glucosyltransferase 1 JBrowse link NW_004936536 6,408,066 6,427,864 RGD:9068941
Dowling-Degos Disease 2 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pofut1 protein O-fucosyltransferase 1 JBrowse link NW_004936485 19,111,704 19,137,689 RGD:7240710
RGD:9068941
Dowling-Degos Disease 4 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Poglut1 protein O-glucosyltransferase 1 JBrowse link NW_004936536 6,408,066 6,427,864 RGD:7240710
RGD:9068941
Hyperpigmentation with or without Hypopigmentation, Familial Progressive term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Kitlg KIT ligand JBrowse link NW_004936507 5,566,144 5,650,412 RGD:7240710
RGD:9068941
Insulin-Resistant Diabetes Mellitus, with Acanthosis Nigricans term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Insr insulin receptor JBrowse link NW_004936588 4,345,306 4,453,380 RGD:7240710
RGD:9068941
Lentigo term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hgf hepatocyte growth factor JBrowse link NW_004936734 354,798 428,356 RGD:9068941
LEOPARD syndrome term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Braf B-Raf proto-oncogene, serine/threonine kinase JBrowse link NW_004936592 4,728,371 4,833,830 RGD:9068941
G Epha2 EPH receptor A2 JBrowse link NW_004936474 3,648,395 3,673,856 RGD:9068941
G Ppp1r13l protein phosphatase 1 regulatory subunit 13 like JBrowse link NW_004936706 1,835,306 1,846,821 RGD:9068941
G Pten phosphatase and tensin homolog JBrowse link NW_004936735 1,252,414 1,338,318 RGD:9068941
G Ptpn11 protein tyrosine phosphatase non-receptor type 11 JBrowse link NW_004936668 2,602,261 2,687,903 RGD:9068941
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase JBrowse link NW_004936602 1,089,979 1,114,376 RGD:9068941
G Rpl6 ribosomal protein L6 JBrowse link NW_004936668 2,584,829 2,588,236 RGD:9068941
LEOPARD Syndrome 1 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ptpn11 protein tyrosine phosphatase non-receptor type 11 JBrowse link NW_004936668 2,602,261 2,687,903 RGD:7240710
RGD:9068941
LEOPARD Syndrome 2 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase JBrowse link NW_004936602 1,089,979 1,114,376 RGD:7240710
RGD:9068941
LEOPARD Syndrome 3 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Braf B-Raf proto-oncogene, serine/threonine kinase JBrowse link NW_004936592 4,728,371 4,833,830 RGD:7240710
RGD:9068941
Melanosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aldh2 aldehyde dehydrogenase 2 family member JBrowse link NW_004936558 4,362,693 4,387,705 RGD:9068941
Neurocutaneous Melanosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nras NRAS proto-oncogene, GTPase JBrowse link NW_004936627 73,413 82,590 RGD:7240710
RGD:9068941
Peutz-Jeghers syndrome term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abca7 ATP binding cassette subfamily A member 7 JBrowse link NW_004936588 460,308 477,382 RGD:9068941
G Arhgap45 Rho GTPase activating protein 45 JBrowse link NW_004936588 478,708 492,029 RGD:9068941
G Arid3a AT-rich interaction domain 3A JBrowse link NW_004936588 389,213 418,360 RGD:9068941
G Cbarp CACN subunit beta associated regulatory protein JBrowse link NW_004936588 601,108 607,823 RGD:9068941
G Cfd complement factor D JBrowse link NW_004936588 350,925 352,732 RGD:9068941
G Cnn2 calponin 2 JBrowse link NW_004936588 453,908 459,916 RGD:9068941
G Gpx4 glutathione peroxidase 4 JBrowse link NW_004936588 506,101 508,469 RGD:9068941
G Grin3b glutamate ionotropic receptor NMDA type subunit 3B JBrowse link NW_004936588 433,544 440,534 RGD:9068941
G Kiss1r KISS1 receptor JBrowse link NW_004936588 384,195 387,625 RGD:9068941
G Med16 mediator complex subunit 16 JBrowse link NW_004936588 352,723 370,898 RGD:9068941
G Polr2e RNA polymerase II subunit E JBrowse link NW_004936588 494,445 499,659 RGD:9068941
G R3hdm4 R3H domain containing 4 JBrowse link NW_004936588 373,177 382,018 RGD:9068941
G Sbno2 strawberry notch homolog 2 JBrowse link NW_004936588 509,244 556,424 RGD:9068941
G Stk11 serine/threonine kinase 11 JBrowse link NW_004936588 579,816 601,033 RGD:7240710
RGD:9068941
G Tmem259 transmembrane protein 259 JBrowse link NW_004936588 440,460 449,440 RGD:9068941
G Wdr18 WD repeat domain 18 JBrowse link NW_004936588 423,672 429,875 RGD:9068941
reticulate acropigmentation of Kitamura term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adam10 ADAM metallopeptidase domain 10 JBrowse link NW_004936471 19,760,709 19,911,759 RGD:7240710
RGD:9068941
G Krt5 keratin 5 JBrowse link NW_004936512 9,923,593 9,929,517 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 10699
    sensory system disease 3762
      skin disease 1969
        pigmentation disease 181
          Hyperpigmentation 39
            Ataxia-Telangiectasia with Generalized Skin Pigmentation and Early Death 0
            Dermatopathia Pigmentosa Reticularis 0
            Dowling-Degos disease + 4
            Hyperkeratosis-Hyperpigmentation Syndrome 0
            Hyperpigmentation of Fuldauer and Kuijpers 0
            Hyperpigmentation, Familial Progressive + 1
            Melanosis + 31
            Melanosis, Universal 0
            Multiform Ventricular Extrasystoles with Short Stature, Hyperpigmentation and Microcephaly 0
            Patterson Pseudoleprechaunism Syndrome 0
            hyperpigmentation of eyelid 0
Path 2
Term Annotations click to browse term
  disease 10699
    disease of anatomical entity 10235
      nervous system disease 7882
        sensory system disease 3762
          skin disease 1969
            pigmentation disease 181
              Hyperpigmentation 39
                Ataxia-Telangiectasia with Generalized Skin Pigmentation and Early Death 0
                Dermatopathia Pigmentosa Reticularis 0
                Dowling-Degos disease + 4
                Hyperkeratosis-Hyperpigmentation Syndrome 0
                Hyperpigmentation of Fuldauer and Kuijpers 0
                Hyperpigmentation, Familial Progressive + 1
                Melanosis + 31
                Melanosis, Universal 0
                Multiform Ventricular Extrasystoles with Short Stature, Hyperpigmentation and Microcephaly 0
                Patterson Pseudoleprechaunism Syndrome 0
                hyperpigmentation of eyelid 0
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.