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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Reperfusion Injury
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Accession:DOID:9004009 term browser browse the term
Definition:Adverse functional, metabolic, or structural changes in ischemic tissues resulting from the restoration of blood flow to the tissue (REPERFUSION), including swelling; HEMORRHAGE; NECROSIS; and damage from FREE RADICALS. The most common instance is MYOCARDIAL REPERFUSION INJURY.
Synonyms:exact_synonym: Ischemia Reperfusion Injury;   Ischemia-Reperfusion Injuries;   Reperfusion Damage;   Reperfusion Damages;   Reperfusion Injuries
 primary_id: MESH:D015427;   RDO:0006865
For additional species annotation, visit the Alliance of Genome Resources.


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Reperfusion Injury term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A ISO CTD Direct Evidence: marker/mechanism CTD PMID:22749977 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcc5 ATP binding cassette subfamily C member 5 IEP mRNA, protein:increased expression:brain, neuron RGD PMID:16997484 RGD:2301088 NCBI chr11:84,395,982...84,490,215
Ensembl chr11:84,396,033...84,490,211
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 IEP mRNA, protein:increased expression, altered localization:small intestine RGD PMID:18451542 RGD:2315580 NCBI chr 4:88,765,441...88,890,268
Ensembl chr 4:88,832,178...88,890,621
JBrowse link
G Ace angiotensin I converting enzyme IMP RGD PMID:20436217 RGD:2325213 NCBI chr10:94,170,766...94,213,831
Ensembl chr10:94,170,766...94,187,822
JBrowse link
G Adcyap1 adenylate cyclase activating polypeptide 1 IEP mRNA:increased expression:hippocampal granule cell RGD PMID:19647005 RGD:2315956 NCBI chr 9:121,705,897...121,725,736
Ensembl chr 9:121,706,979...121,725,716
JBrowse link
G Adcyap1r1 ADCYAP receptor type I IEP mRNA:decreased expression:dentate gyrus (rat) RGD PMID:19647005 RGD:2315956 NCBI chr 4:85,662,809...85,711,696
Ensembl chr 4:85,662,892...85,711,696
JBrowse link
G Adgrl1 adhesion G protein-coupled receptor L1 IEP RGD PMID:12225880 RGD:2314400 NCBI chr19:25,029,037...25,069,146
Ensembl chr19:25,029,037...25,069,142
JBrowse link
G Adgrl3 adhesion G protein-coupled receptor L3 IEP RGD PMID:12225880 RGD:2314400 NCBI chr14:28,362,176...29,226,085
Ensembl chr14:28,393,394...28,967,980
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing IMP associated with Non-alcoholic Fatty Liver Disease; RGD PMID:18098300 RGD:5686804 NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488
JBrowse link
G Adm adrenomedullin IEP protein:increased expression:plasma: RGD PMID:17263982 RGD:7364988 NCBI chr 1:175,443,189...175,447,260
Ensembl chr 1:175,445,088...175,447,259
JBrowse link
G Adora2a adenosine A2a receptor IDA
ISO
CTD Direct Evidence: therapeutic CTD PMID:27757725, PMID:17937935 RGD:4890367 NCBI chr20:14,265,251...14,282,873
Ensembl chr20:14,265,252...14,282,873
JBrowse link
G Adora2b adenosine A2B receptor ISO CTD Direct Evidence: therapeutic CTD PMID:27757725 NCBI chr10:48,569,563...48,586,366
Ensembl chr10:48,569,555...48,586,365
JBrowse link
G Adrb1 adrenoceptor beta 1 IMP RGD PMID:20451506 RGD:5129116 NCBI chr 1:277,537,585...277,538,985
Ensembl chr 1:277,537,585...277,538,985
JBrowse link
G Adrb2 adrenoceptor beta 2 IDA RGD PMID:14630341, PMID:18336819 RGD:1598754, RGD:4145097 NCBI chr18:57,513,792...57,515,834
Ensembl chr18:57,513,793...57,515,834
JBrowse link
G Agt angiotensinogen ISO CTD Direct Evidence: marker/mechanism CTD PMID:23875703 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433
JBrowse link
G Agtr2 angiotensin II receptor, type 2 IDA RGD PMID:22920387 RGD:6903870 NCBI chr  X:119,389,480...119,393,845
Ensembl chr  X:119,390,013...119,393,842
JBrowse link
G Aif1 allograft inflammatory factor 1 IEP protein:increased expression:Kupffer cell (rat) RGD PMID:16500929 RGD:2313040 NCBI chr20:5,161,350...5,167,176
Ensembl chr20:5,161,333...5,166,448
JBrowse link
G Akt1 AKT serine/threonine kinase 1 ISO RGD PMID:21351045 RGD:5509067 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Akt1s1 AKT1 substrate 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16397181 NCBI chr 1:100,845,443...100,851,961
Ensembl chr 1:100,845,563...100,851,960
JBrowse link
G Alb albumin IEP mRNA, protein:increased expression:brain RGD PMID:20193666 RGD:2325686 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Aldoa aldolase, fructose-bisphosphate A IEP RGD PMID:10395295 RGD:1599061 NCBI chr 1:198,228,387...198,233,988
Ensembl chr 1:198,228,387...198,233,588
JBrowse link
G Alox12 arachidonate 12-lipoxygenase, 12S type IEP RGD PMID:15518705 RGD:5509617 NCBI chr10:56,851,734...56,864,049
Ensembl chr10:56,851,734...56,864,005
JBrowse link
G Alox15 arachidonate 15-lipoxygenase ISO RGD PMID:18635843 RGD:5509608 NCBI chr10:56,953,692...56,962,145
Ensembl chr10:56,953,691...56,962,161
JBrowse link
G Alox5 arachidonate 5-lipoxygenase IEP
ISO
IMP
protein:increased expression:cerebral hemisphere
CTD Direct Evidence: marker/mechanism
CTD PMID:15266012, PMID:14769366, PMID:19816089 RGD:1626152, RGD:2317531 NCBI chr 4:148,398,004...148,446,308
Ensembl chr 4:148,398,892...148,446,303
JBrowse link
G Ang angiogenin IEP protein:increased expression:brain RGD PMID:19666176 RGD:2325717 NCBI chr15:28,022,926...28,028,636 JBrowse link
G Angpt1 angiopoietin 1 ISO RGD PMID:19885826 RGD:2316041 NCBI chr 7:81,338,327...81,592,459
Ensembl chr 7:81,342,280...81,592,206
JBrowse link
G Aoc3 amine oxidase, copper containing 3 IMP RGD PMID:16339390 RGD:2313821 NCBI chr10:89,251,370...89,259,313
Ensembl chr10:89,251,370...89,259,313
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 IEP RGD PMID:18205898 RGD:2292105 NCBI chr 7:31,699,309...31,784,192
Ensembl chr 7:31,699,885...31,784,192
JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 IEP protein:increased expression:placenta RGD PMID:18373555 RGD:2315671 NCBI chr15:27,849,943...27,852,083
Ensembl chr15:27,849,979...27,852,082
JBrowse link
G Aqp4 aquaporin 4 IEP
ISO
protein:increased expression:cerebral cortex
mRNA, protein:increased expression:parietal cortex
RGD PMID:20979759, PMID:21718723, PMID:19806476, PMID:20924629 RGD:5148016, RGD:5684013, RGD:5148037, RGD:5148022 NCBI chr18:6,766,009...6,782,757
Ensembl chr18:6,765,945...6,782,996
JBrowse link
G Arg1 arginase 1 IEP protein:increased expression:serum (rat) RGD PMID:17023552 RGD:4143185 NCBI chr 1:21,525,421...21,537,872
Ensembl chr 1:21,525,421...21,537,863
JBrowse link
G Asl argininosuccinate lyase resistance IEP protein:increased expression:brain, neuron (rat) RGD PMID:17198704 RGD:1599263 NCBI chr12:30,160,922...30,178,348
Ensembl chr12:30,165,694...30,178,341
JBrowse link
G Ass1 argininosuccinate synthase 1 resistance IEP protein:increased expression:brain, neuron (rat) RGD PMID:17198704 RGD:1599263 NCBI chr 3:10,327,411...10,375,847
Ensembl chr 3:10,327,414...10,375,826
JBrowse link
G Bad BCL2-associated agonist of cell death IEP protein:altered localization:brain, mitochondria RGD PMID:18347331 RGD:2292679 NCBI chr 1:222,198,516...222,207,459
Ensembl chr 1:222,198,534...222,207,453
JBrowse link
G Bag1 BAG cochaperone 1 IMP RGD PMID:12215270 RGD:2296021 NCBI chr 5:57,254,421...57,267,002
Ensembl chr 5:57,254,421...57,267,002
JBrowse link
G Bag3 BAG cochaperone 3 IEP protein:increased expression:hippocampus, astrocyte RGD PMID:12061864 RGD:2325848 NCBI chr 1:199,941,258...199,965,191
Ensembl chr 1:199,941,161...199,965,191
JBrowse link
G Bax BCL2 associated X, apoptosis regulator IEP protein:increased expression:brain RGD PMID:18083315, PMID:18221257 RGD:2290557, RGD:2293026 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator ISO CTD Direct Evidence: therapeutic CTD PMID:15449323 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bdnf brain-derived neurotrophic factor IEP mRNA:increased expression:retina RGD PMID:20554625 RGD:4891135 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210
JBrowse link
G Becn1 beclin 1 IEP protein:increased expression:brain RGD PMID:22306244 RGD:6483054 NCBI chr10:89,209,944...89,225,297
Ensembl chr10:89,209,940...89,225,297
JBrowse link
G Bid BH3 interacting domain death agonist IDA RGD PMID:19888517 RGD:2317562 NCBI chr 4:153,439,812...153,465,247
Ensembl chr 4:153,442,218...153,465,203
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 IEP
IMP
protein:increased expression:brain RGD PMID:18159002, PMID:18053646 RGD:2293126, RGD:2293127 NCBI chr10:106,856,097...106,864,419
Ensembl chr10:106,856,097...106,864,413
JBrowse link
G Bmp6 bone morphogenetic protein 6 IEP RGD PMID:11245809 RGD:2289024 NCBI chr17:26,955,142...27,112,820
Ensembl chr17:26,955,142...27,112,820
JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 IEP mRNA:increased expression:dentate gyrus, granule cell RGD PMID:10996456 RGD:5129486 NCBI chr 9:66,568,074...66,683,019
Ensembl chr 9:66,568,074...66,676,494
JBrowse link
G Bsg basigin (Ok blood group) IEP protein:increased expression:basal ganglia RGD PMID:16029217 RGD:2289063 NCBI chr 7:12,875,536...12,882,753
Ensembl chr 7:12,875,537...12,882,753
JBrowse link
G Btg2 BTG anti-proliferation factor 2 IEP mRNA:increased expression:kidney RGD PMID:9712737 RGD:2289078 NCBI chr13:50,913,185...50,916,944
Ensembl chr13:50,913,180...50,916,982
JBrowse link
G C3 complement C3 IEP protein:increased expression:intestine RGD PMID:17981193 RGD:5129536 NCBI chr 9:9,721,137...9,747,084
Ensembl chr 9:9,721,105...9,747,167
JBrowse link
G C3ar1 complement C3a receptor 1 IMP RGD PMID:15159277 RGD:5129702 NCBI chr 4:155,681,767...155,691,240
Ensembl chr 4:155,684,029...155,690,869
JBrowse link
G C5 complement C5 IDA RGD PMID:15158333 RGD:1600597 NCBI chr 3:14,049,993...14,113,931
NCBI chr 3:14,206,466...14,229,141
Ensembl chr 3:14,049,995...14,229,080
JBrowse link
G C5ar1 complement C5a receptor 1 IMP RGD PMID:15158333, PMID:15159277 RGD:1600597, RGD:5129702 NCBI chr 1:78,186,777...78,195,132
Ensembl chr 1:78,186,776...78,195,328
JBrowse link
G Casp1 caspase 1 IMP RGD PMID:17845807 RGD:2315890 NCBI chr 8:2,605,743...2,614,637
Ensembl chr 8:2,604,962...2,614,631
JBrowse link
G Casp12 caspase 12 IEP RGD PMID:18273070 RGD:2311461 NCBI chr 8:2,658,892...2,686,160
Ensembl chr 8:2,659,865...2,686,160
JBrowse link
G Casp3 caspase 3 treatment IMP
IDA
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:23875703, PMID:18490106, PMID:29568770 RGD:2293311, RGD:13792595 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp6 caspase 6 IEP protein:increased expression, increased activity:small intestine mucosa RGD PMID:15010362 RGD:2301320 NCBI chr 2:235,341,326...235,353,715
Ensembl chr 2:235,341,365...235,353,967
Ensembl chr 2:235,341,365...235,353,967
JBrowse link
G Casp8 caspase 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23875703 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 treatment IDA RGD PMID:29568770 RGD:13792595 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cast calpastatin IEP RGD PMID:11035539 RGD:5509823 NCBI chr 2:1,452,111...1,561,669
Ensembl chr 2:1,452,116...1,561,464
JBrowse link
G Cat catalase IDA
ISO
IEP
CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:8215636, PMID:16682413, PMID:23743330, PMID:23875703, PMID:19196076, PMID:20888583 RGD:5130760, RGD:5130200 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cav1 caveolin 1 IEP protein:increased expression:brain RGD PMID:17293479 RGD:2289123 NCBI chr 4:44,597,123...44,630,206
Ensembl chr 4:44,597,123...44,630,200
JBrowse link
G Ccl11 C-C motif chemokine ligand 11 IEP mRNA:increased expression:aorta RGD PMID:9665468 RGD:4145482 NCBI chr10:69,434,965...69,439,566
Ensembl chr10:69,434,941...69,439,575
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 treatment IDA
ISO
Gastric Reperfusion Injury
CTD Direct Evidence: marker/mechanism
CTD PMID:12468449, PMID:15829914, PMID:22611311 RGD:8549744 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15829914 NCBI chr10:70,869,516...70,871,066
Ensembl chr10:70,869,513...70,871,066
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 ISO
IEP
protein:increased secretion:lung, secretion (mouse)
protein:increased expression:gut
RGD PMID:19558673, PMID:15542513 RGD:4891479, RGD:2307184 NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315
JBrowse link
G Ccnb1 cyclin B1 IEP protein;altered expression:cerebral cortex, hippocampus CA1, neuron RGD PMID:18278459 RGD:2315990 NCBI chr 2:30,782,133...30,791,106
Ensembl chr 2:30,783,915...30,791,221
JBrowse link
G Ccnd1 cyclin D1 IEP RGD PMID:16718823 RGD:2289145 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Ccne1 cyclin E1 IEP protein:decreased expression:liver RGD PMID:17584601 RGD:2289275 NCBI chr 1:94,485,830...94,495,112
Ensembl chr 1:94,485,832...94,494,980
JBrowse link
G Ccng1 cyclin G1 IEP mRNA, protein:increased expression:brain RGD PMID:9698156 RGD:2316027 NCBI chr10:25,903,925...25,910,298
Ensembl chr10:25,903,911...25,910,325
JBrowse link
G Ccr1 C-C motif chemokine receptor 1 ISO mRNA:increased expression:kidney RGD PMID:20410256 RGD:5688141 NCBI chr 8:132,996,646...133,002,201
Ensembl chr 8:132,996,649...133,002,201
JBrowse link
G Cd2ap CD2-associated protein IEP RGD PMID:16088078 RGD:1581187 NCBI chr 9:20,794,680...20,858,438
Ensembl chr 9:20,765,296...20,858,504
JBrowse link
G Cd36 CD36 molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:16526316 NCBI chr 4:14,150,309...14,191,498
Ensembl chr 4:14,001,761...14,249,749
JBrowse link
G Cd40 CD40 molecule IMP RGD PMID:12388354 RGD:5508171 NCBI chr 3:161,519,789...161,534,943
Ensembl chr 3:161,519,743...161,534,704
JBrowse link
G Cd40lg CD40 ligand ISO
IMP
RGD PMID:20659085, PMID:12388354 RGD:5490531, RGD:5508171 NCBI chr  X:159,703,703...159,714,886
Ensembl chr  X:159,703,578...159,716,562
JBrowse link
G Cd44 CD44 molecule (Indian blood group) IEP protein:increased expression:kidney
protein:increased expression:testis, macrophage
RGD PMID:16786159, PMID:16891795 RGD:2289354, RGD:2289369 NCBI chr 3:92,695,083...92,783,820
Ensembl chr 3:92,696,313...92,783,658
JBrowse link
G Cd55 CD55 molecule (Cromer blood group) IEP RGD PMID:20403613 RGD:2326175 NCBI chr13:47,125,156...47,153,557
Ensembl chr13:47,126,741...47,154,292
JBrowse link
G Cd59 CD59 molecule IDA RGD PMID:10530491 RGD:1600493 NCBI chr 3:94,010,481...94,028,660
Ensembl chr 3:94,010,475...94,028,621
JBrowse link
G Cdc42 cell division cycle 42 IDA protein:increased activation:hippocampus CA1 RGD PMID:17161586 RGD:2298583 NCBI chr 5:155,690,267...155,728,385
Ensembl chr 5:155,691,390...155,728,300
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A IEP
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:16968891, PMID:10451498 RGD:10043817 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B IEP protein:increased expression:skeletal muscle RGD PMID:15799773 RGD:2293627 NCBI chr 4:168,689,043...168,694,159
Ensembl chr 4:168,689,163...168,693,964
JBrowse link
G Cfh complement factor H IEP protein:increased expression:plasma: RGD PMID:17263982 RGD:7364988 NCBI chr13:56,979,155...57,080,540
Ensembl chr13:56,978,607...57,080,622
JBrowse link
G Chat choline O-acetyltransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:23075401 NCBI chr16:8,576,858...8,686,131
Ensembl chr16:8,577,840...8,686,131
JBrowse link
G Cldn4 claudin 4 IEP protein:increased expression, altered localization:small intestine epithelium RGD PMID:17375208 RGD:2317600 NCBI chr12:24,761,210...24,763,008
Ensembl chr12:24,761,210...24,763,005
JBrowse link
G Cnr1 cannabinoid receptor 1 IMP RGD PMID:19372445 RGD:2314674 NCBI chr 5:49,307,584...49,333,064
Ensembl chr 5:49,311,030...49,333,056
JBrowse link
G Cspg4 chondroitin sulfate proteoglycan 4 IEP RGD PMID:17565360 RGD:5686869 NCBI chr 8:61,532,465...61,567,510
Ensembl chr 8:61,532,465...61,567,510
JBrowse link
G Ctsb cathepsin B IEP protein:increased expression:cerebral cortex, mitochondrion (rat) RGD PMID:18938146 RGD:2315506 NCBI chr15:46,316,741...46,337,613
Ensembl chr15:46,316,741...46,337,612
JBrowse link
G Ctsg cathepsin G ISO RGD PMID:17322378 RGD:7242055 NCBI chr15:35,107,333...35,113,678
Ensembl chr15:35,111,091...35,113,678
JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 IEP mRNA, protein:increased expression:brain RGD PMID:19563789 RGD:4891956 NCBI chr19:10,644,267...10,654,861
Ensembl chr19:10,644,244...10,653,800
JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 ISO
IEP
mRNA:increased expression:liver
CTD Direct Evidence: marker/mechanism
CTD PMID:16526316, PMID:20160675, PMID:10655268 RGD:5134970, RGD:5135270 NCBI chr14:18,743,678...18,745,457
Ensembl chr14:18,743,685...18,745,457
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 IEP
ISO
mRNA:increased expression:liver
protein:increased expression:respiratory system fluid/secretion
associated with Anemia, Sickle Cell;protein:increased expression:lung
RGD PMID:18589091, PMID:16709871, PMID:19433855 RGD:2311376, RGD:5135441, RGD:5135307 NCBI chr14:17,210,733...17,212,930
Ensembl chr14:17,210,733...17,212,930
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 IEP protein:increased expression:retina RGD PMID:18709383 RGD:2306570 NCBI chr 4:149,261,044...149,273,891
Ensembl chr 4:149,261,044...149,273,891
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 IEP
ISO
mRNA:increased expression:jejunum, lung
CTD Direct Evidence: marker/mechanism
protein:increased expression:liver
mRNA:increased expression:liver
CTD PMID:12468449, PMID:19691980, PMID:10655268, PMID:11580116, PMID:20160675 RGD:5134974, RGD:5135270, RGD:5135251, RGD:5134970 NCBI chr14:18,731,346...18,733,391
Ensembl chr14:18,731,378...18,733,391
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16526316 NCBI chr14:18,820,168...18,839,659
Ensembl chr14:18,820,168...18,839,595
JBrowse link
G Cxcl6 C-X-C motif chemokine ligand 6 IEP protein:increased expression:liver RGD PMID:11580116, PMID:10655268 RGD:5135251, RGD:5135270 NCBI chr14:18,860,201...18,920,839
Ensembl chr14:18,860,264...18,862,407
JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 ISO associated with Anemia, Sickle Cell;protein:increased expression:lung RGD PMID:19433855 RGD:5135307 NCBI chr14:17,228,832...17,233,743
Ensembl chr14:17,228,856...17,234,712
JBrowse link
G Cxcr3 C-X-C motif chemokine receptor 3 IEP mRNA:increased expression:liver RGD PMID:18589091 RGD:2311376 NCBI chr  X:71,614,346...71,616,997
Ensembl chr  X:71,614,346...71,616,997
JBrowse link
G Cyba cytochrome b-245 alpha chain IEP RGD PMID:15148062 RGD:1599683 NCBI chr19:55,249,634...55,257,824
Ensembl chr19:55,249,616...55,257,876
JBrowse link
G Cybb cytochrome b-245 beta chain IEP
ISO
Protein:increase expression:brain
CTD Direct Evidence: marker/mechanism
CTD PMID:19193722, PMID:16766636 RGD:1599677 NCBI chr  X:14,578,330...14,610,049
Ensembl chr  X:14,578,264...14,612,547
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 IEP protein:increased expression:hippocampus (rat) RGD PMID:21114983 RGD:4890041 NCBI chr 8:58,744,849...58,772,408
Ensembl chr 8:58,744,849...58,772,408
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 IEP protein:decreased expression:liver RGD PMID:21094789 RGD:4892235 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Cyp3a62 cytochrome P450, family 3, subfamily a, polypeptide 62 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22749977 NCBI chr12:18,679,809...18,709,397
Ensembl chr12:18,678,594...18,709,397
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22749977 NCBI chr12:19,074,288...19,114,491
Ensembl chr12:19,074,583...19,114,399
JBrowse link
G Cysltr1 cysteinyl leukotriene receptor 1 IEP protein:increased expression:kidney RGD PMID:18790177 RGD:4781446 NCBI chr  X:77,671,028...77,700,491
Ensembl chr  X:77,674,150...77,700,269
JBrowse link
G Cysltr2 cysteinyl leukotriene receptor 2 IEP protein:increased expression:brain RGD PMID:21664436 RGD:5144004 NCBI chr15:54,903,290...54,941,742
Ensembl chr15:54,905,274...54,906,203
JBrowse link
G Dcc DCC netrin 1 receptor IEP protein:increased expression:brain RGD PMID:17574219 RGD:2314372 NCBI chr18:66,518,213...67,629,801
Ensembl chr18:66,523,120...67,224,566
JBrowse link
G Dsg1 desmoglein 1 IEP protein:decreased expression:lung RGD PMID:19500802 RGD:2316254 NCBI chr18:12,008,301...12,040,337
Ensembl chr18:12,008,759...12,038,053
JBrowse link
G Edn1 endothelin 1 IEP
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:17470888, PMID:18722366 RGD:4892577 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Edn2 endothelin 2 IEP RGD PMID:1479622 RGD:1580920 NCBI chr 5:139,098,472...139,106,396
Ensembl chr 5:139,100,898...139,105,792
JBrowse link
G Ednrb endothelin receptor type B IEP RGD PMID:18722366 RGD:4892577 NCBI chr15:88,004,775...88,036,354
Ensembl chr15:88,006,977...88,036,354
JBrowse link
G Eef2 eukaryotic translation elongation factor 2 IEP protein:hypophosphorylation:cortex, hippocampus: RGD PMID:15211596 RGD:10401223 NCBI chr 7:11,401,501...11,406,771
Ensembl chr 7:11,401,501...11,406,771
JBrowse link
G Efna5 ephrin A5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16526316 NCBI chr 9:110,054,002...110,329,878
Ensembl chr 9:110,057,155...110,225,486
JBrowse link
G Efnb2 ephrin B2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16526316 NCBI chr16:86,631,151...86,672,050
Ensembl chr16:86,631,064...86,675,049
JBrowse link
G Egf epidermal growth factor resistance ISO CTD Direct Evidence: marker/mechanism CTD PMID:16526316, PMID:16417467 RGD:6906916 NCBI chr 2:68,820,616...68,895,537 JBrowse link
G Egr1 early growth response 1 ISO
IEP
Lung Reperfusion Injury
CTD Direct Evidence: marker/mechanism
Lung Reperfusion Injury; protein:increased expression:lung, nucleus (rat)
Lung Reperfusion Injury; protein:increased expression:lung, nucleus (mouse)
CTD PMID:12468449, PMID:16551742, PMID:16488723, PMID:19342415 RGD:5131903, RGD:5131904, RGD:5131887 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429
JBrowse link
G Eif2a eukaryotic translation initiation factor 2A ISO CTD Direct Evidence: marker/mechanism CTD PMID:19041636 NCBI chr 2:148,722,343...148,755,781
Ensembl chr 2:148,722,231...148,755,520
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 IDA protein:increased phosphorylation:kidney RGD PMID:15936177 RGD:1581062 NCBI chr 4:98,648,513...98,709,695
Ensembl chr 4:98,648,545...98,709,694
JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha IDA protein:increased phosphorylation:kidney RGD PMID:15936177 RGD:1581062 NCBI chr 6:102,048,372...102,073,041
Ensembl chr 6:102,048,372...102,073,041
JBrowse link
G Eno2 enolase 2 IDA RGD PMID:17683050 RGD:2293745 NCBI chr 4:157,285,192...157,294,090
Ensembl chr 4:157,285,179...157,294,047
JBrowse link
G Ep300 E1A binding protein p300 treatment IDA
IEP
retina
retina; protein:altered localization:Hsp70, promoter (rat)
RGD PMID:22143029, PMID:22143029 RGD:5686888, RGD:5686888 NCBI chr 7:122,818,194...122,889,055
Ensembl chr 7:122,818,975...122,861,296
JBrowse link
G Epha2 Eph receptor A2 IDA RGD PMID:16735461 RGD:1580976 NCBI chr 5:159,845,773...159,874,203
Ensembl chr 5:159,845,774...159,874,206
JBrowse link
G Ephx2 epoxide hydrolase 2 ISO RGD PMID:19471280 RGD:5688359 NCBI chr15:42,757,241...42,794,211
Ensembl chr15:42,757,235...42,794,279
JBrowse link
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit IMP RGD PMID:19440222 RGD:2313668 NCBI chr 1:80,256,973...80,268,198
Ensembl chr 1:80,256,973...80,268,198
JBrowse link
G Ets1 ETS proto-oncogene 1, transcription factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:16526316 NCBI chr 8:33,756,634...33,879,625
Ensembl chr 8:33,816,386...33,879,625
JBrowse link
G F2 coagulation factor II IMP RGD PMID:20705928 RGD:5147777 NCBI chr 3:80,529,468...80,542,993
Ensembl chr 3:80,529,428...80,543,031
JBrowse link
G Fas Fas cell surface death receptor treatment IDA RGD PMID:29568770 RGD:13792595 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Fgf1 fibroblast growth factor 1 IDA
ISO
Rat model using human FGF1 RGD PMID:19497570, PMID:16635575 RGD:5509879, RGD:5509881 NCBI chr18:32,273,830...32,359,831
Ensembl chr18:32,273,770...32,359,824
JBrowse link
G Fgf2 fibroblast growth factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16526316 NCBI chr 2:124,081,072...124,134,133
Ensembl chr 2:124,081,072...124,134,681
JBrowse link
G Fgf7 fibroblast growth factor 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16526316 NCBI chr 3:118,315,859...118,368,464
Ensembl chr 3:118,317,761...118,366,872
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit IEP
ISO
protein:increased expression:brain
CTD Direct Evidence: marker/mechanism
CTD PMID:7922267, PMID:15121240 RGD:2293779 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit IEP mRNA:increased expression:hippocampus RGD PMID:15306117 RGD:1642465 NCBI chr 1:220,826,560...220,835,066
Ensembl chr 1:220,826,560...220,835,066
JBrowse link
G Fosl2 FOS like 2, AP-1 transcription factor subunit IEP protein:increased expression:brain RGD PMID:15121240 RGD:2293779 NCBI chr 6:25,598,936...25,616,995
Ensembl chr 6:25,598,936...25,616,995
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase IEP RGD PMID:17250641 RGD:2307361 NCBI chr  X:156,274,800...156,293,935
Ensembl chr  X:156,274,800...156,293,926
JBrowse link
G Gast gastrin ISO CTD Direct Evidence: marker/mechanism CTD PMID:10594344 NCBI chr10:88,245,532...88,248,485
Ensembl chr10:88,245,532...88,248,484
JBrowse link
G Gh1 growth hormone 1 treatment ISO RGD PMID:21439711 RGD:10003153 NCBI chr10:94,486,204...94,488,181
Ensembl chr10:94,486,205...94,488,180
JBrowse link
G Ghrl ghrelin and obestatin prepropeptide ISO CTD Direct Evidence: therapeutic CTD PMID:16581065 NCBI chr 4:145,674,157...145,678,066
Ensembl chr 4:145,674,157...145,678,066
JBrowse link
G Gjb1 gap junction protein, beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25530438 NCBI chr  X:71,272,030...71,279,973
Ensembl chr  X:71,272,042...71,279,977
JBrowse link
G Glud1 glutamate dehydrogenase 1 IEP protein:decreased activity:brain RGD PMID:7808037 RGD:6484655 NCBI chr16:10,661,486...10,695,557
Ensembl chr16:10,662,021...10,695,557
JBrowse link
G Gnai2 G protein subunit alpha i2 IEP RGD PMID:11367746 RGD:13513922 NCBI chr 8:116,370,730...116,391,337
Ensembl chr 8:116,370,744...116,391,307
JBrowse link
G Gnai3 G protein subunit alpha i3 IEP RGD PMID:11367746 RGD:13513922 NCBI chr 2:210,896,779...210,934,733
Ensembl chr 2:210,896,656...210,934,749
JBrowse link
G Gpt glutamic--pyruvic transaminase ISO CTD Direct Evidence: marker/mechanism CTD PMID:8215636 NCBI chr 7:117,759,083...117,761,932
Ensembl chr 7:117,759,083...117,761,931
JBrowse link
G Gpx1 glutathione peroxidase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23743330 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522
JBrowse link
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 IEP mRNA:decreased expression:hippocampus (rat) RGD PMID:20408958 RGD:4107069 NCBI chr10:42,441,723...42,760,200
Ensembl chr10:42,614,713...42,760,200
JBrowse link
G Grik2 glutamate ionotropic receptor kainate type subunit 2 IMP RGD PMID:17639597 RGD:2316528 NCBI chr20:53,791,428...54,517,691
Ensembl chr20:53,789,760...54,517,709
JBrowse link
G Grik5 glutamate ionotropic receptor kainate type subunit 5 IMP RGD PMID:17639597 RGD:2316528 NCBI chr 1:81,885,516...81,946,731
Ensembl chr 1:81,885,521...81,946,714
JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A IEP mRNA, protein:decreased expression:cerebral cortex, hippocampus (rat) RGD PMID:20350575 RGD:2325867 NCBI chr10:5,707,806...6,123,568
Ensembl chr10:5,930,298...6,119,990
JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B IEP mRNA, protein:decreased expression:cerebral cortex, hippocampus (rat) RGD PMID:20350575 RGD:2325867 NCBI chr 4:169,541,620...170,000,216
Ensembl chr 4:169,560,387...169,999,873
JBrowse link
G Gsr glutathione-disulfide reductase treatment IEP associated with Diabetes Mellitus, Experimental RGD PMID:24904723 RGD:10401882 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Gstp1 glutathione S-transferase pi 1 ISO RGD PMID:17142801 RGD:6903953 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
G Hbegf heparin-binding EGF-like growth factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:7635938 NCBI chr18:29,330,302...29,340,185
Ensembl chr18:29,329,764...29,340,403
JBrowse link
G Hgf hepatocyte growth factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:16526316 NCBI chr 4:15,435,460...15,505,377
Ensembl chr 4:15,433,295...15,505,362
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha treatment IDA Spinal Cord Reperfusion Injury
Limb Reperfusion Injury
RGD PMID:16465055, PMID:23816242 RGD:9068924, RGD:9068927 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Hmgb1 high mobility group box 1 treatment IMP RGD PMID:22392147 RGD:10402071 NCBI chr12:7,082,529...7,090,246
Ensembl chr16:37,500,017...37,502,237
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase IMP
ISO
associated with Diabetes Mellitus, Experimental RGD PMID:21724106, PMID:16009498, PMID:18398369 RGD:5508445, RGD:5508473, RGD:2315888 NCBI chr 2:27,480,224...27,500,654
Ensembl chr 2:27,480,226...27,500,654
JBrowse link
G Hmox1 heme oxygenase 1 IDA
ISO
IEP
IMP
CTD Direct Evidence: marker/mechanism|therapeutic
protein:increased expression:serum, Bronchoalveolar Lavage Fluid
CTD PMID:12352873, PMID:16982915, PMID:17660127, PMID:17906103, PMID:23075401, PMID:25780291, PMID:16699460, PMID:19885035, PMID:12919086 RGD:1582708, RGD:4145338, RGD:4145514 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hrh3 histamine receptor H3 IDA RGD PMID:17169356 RGD:1626416 NCBI chr 3:175,474,310...175,479,395
Ensembl chr 3:175,473,078...175,479,395
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A ISO CTD Direct Evidence: marker/mechanism CTD PMID:7922267 NCBI chr20:4,875,834...4,881,751
Ensembl chr20:4,877,324...4,879,779
JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B ISO
IEP
RGD PMID:10965299, PMID:10550516 RGD:7242748, RGD:7242749 NCBI chr20:4,877,638...4,880,112
Ensembl chr20:2,699,712...2,701,815
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 IMP associated with Diabetes Mellitus, experimental (D003921): protein:increased expression:brain RGD PMID:22075494 RGD:5685650 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 ISO CTD Direct Evidence: therapeutic CTD PMID:10216529 NCBI chr 8:44,989,401...44,993,261
Ensembl chr 8:44,990,014...44,993,179
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 ISO CTD Direct Evidence: therapeutic CTD PMID:19193722 NCBI chr12:23,839,390...23,841,051
Ensembl chr12:23,839,399...23,841,049
JBrowse link
G Icam1 intercellular adhesion molecule 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11557319, PMID:23743330 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Id3 inhibitor of DNA binding 3, HLH protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:16526316 NCBI chr 5:154,489,603...154,491,172
Ensembl chr 5:154,489,590...154,491,223
JBrowse link
G Ifng interferon gamma IEP protein:increased expression:plasma RGD PMID:19514843 RGD:2308950 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Igf1 insulin-like growth factor 1 ISO RGD PMID:16306169 RGD:1598442 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
JBrowse link
G Il10 interleukin 10 IEP
ISO
IDA
CTD Direct Evidence: marker/mechanism CTD PMID:18460982, PMID:19514843, PMID:12388354, PMID:16141682 RGD:2308950, RGD:5508171, RGD:1598625 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il12a interleukin 12A ISO CTD Direct Evidence: marker/mechanism CTD PMID:16526316 NCBI chr 2:165,076,945...165,083,996
Ensembl chr 2:165,076,607...165,084,318
JBrowse link
G Il13 interleukin 13 IEP
ISO
protein:decreased expression:plasma RGD PMID:18354382, PMID:18354382 RGD:2301685, RGD:2301685 NCBI chr10:38,982,909...38,985,466
Ensembl chr10:38,982,909...38,985,466
JBrowse link
G Il18 interleukin 18 ISO protein:increased expression:serum RGD PMID:19394645, PMID:16052682 RGD:4889555, RGD:4889825 NCBI chr 8:55,009,666...55,016,286
Ensembl chr 8:54,993,859...55,016,299
JBrowse link
G Il1a interleukin 1 alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:23875703 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il1b interleukin 1 beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:10594344, PMID:12468449, PMID:15829914, PMID:19058328, PMID:19673871 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il6 interleukin 6 IEP
ISO
CTD Direct Evidence: marker/mechanism
protein:increased expression:lung
CTD PMID:15829914, PMID:17032661, PMID:18258783, PMID:19673871, PMID:21940958, PMID:20680426, PMID:20659747 RGD:4143250, RGD:4143253 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Il6r interleukin 6 receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:21940958 NCBI chr 2:189,196,180...189,255,987
Ensembl chr 2:189,205,701...189,254,628
JBrowse link
G Il6st interleukin 6 signal transducer ISO CTD Direct Evidence: marker/mechanism CTD PMID:21940958 NCBI chr 2:44,279,199...44,319,427
Ensembl chr 2:44,289,393...44,314,944
JBrowse link
G Inpp5d inositol polyphosphate-5-phosphatase D ISO CTD Direct Evidence: therapeutic CTD PMID:25780291 NCBI chr 9:94,745,220...94,850,778
Ensembl chr 9:94,745,217...94,850,771
JBrowse link
G Irak3 interleukin-1 receptor-associated kinase 3 ISO CTD Direct Evidence: therapeutic CTD PMID:25780291 NCBI chr 7:64,922,830...64,982,224
Ensembl chr 7:64,923,615...64,982,281
JBrowse link
G Irf1 interferon regulatory factor 1 IEP mRNA:increased expression:cerebral cortex RGD PMID:12437578 RGD:632385 NCBI chr10:39,109,530...39,116,532
Ensembl chr10:39,109,522...39,116,531
JBrowse link
G Itga2b integrin subunit alpha 2b IMP RGD PMID:11705748 RGD:2316361 NCBI chr10:90,397,960...90,416,550
Ensembl chr10:90,398,132...90,415,070
JBrowse link
G Itga5 integrin subunit alpha 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16526316 NCBI chr 7:144,970,444...144,993,652
Ensembl chr 7:144,970,444...144,993,652
JBrowse link
G Itgb3 integrin subunit beta 3 IMP RGD PMID:11705748 RGD:2316361 NCBI chr10:92,667,869...92,783,413
Ensembl chr10:92,667,869...92,783,410
JBrowse link
G Jak2 Janus kinase 2 ISO RGD PMID:20440769 RGD:6483026 NCBI chr 1:247,398,667...247,457,521
Ensembl chr 1:247,398,598...247,458,509
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:7922267 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Kcnj8 potassium inwardly-rectifying channel, subfamily J, member 8 IDA RGD PMID:10708603 RGD:1581697 NCBI chr 4:176,783,287...176,789,143
Ensembl chr 4:176,782,498...176,789,304
JBrowse link
G Kdr kinase insert domain receptor IEP
ISO
mRNA:increased expression:hippocampus
CTD Direct Evidence: marker/mechanism
CTD PMID:16526316, PMID:17402857 RGD:5684415 NCBI chr14:34,727,677...34,787,127
Ensembl chr14:34,727,623...34,787,183
JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 ISO
IEP
protein:decreased expression:brain, neuron, cytoplasm (mouse)
protein:decreased expression:left coronary artery (rat)
RGD PMID:21075092, PMID:18078953 RGD:6893270, RGD:6902919 NCBI chr 8:22,250,518...22,259,868
Ensembl chr 8:22,250,518...22,259,779
JBrowse link
G Klk1 kallikrein 1 IEP RGD PMID:12746231 RGD:1641806 NCBI chr 1:100,131,562...100,135,556
Ensembl chr 1:100,059,967...100,203,329
Ensembl chr 1:100,059,967...100,203,329
Ensembl chr 1:100,059,967...100,203,329
JBrowse link
G Ldlr low density lipoprotein receptor IEP RGD PMID:17288738 RGD:2324630 NCBI chr 8:22,750,425...22,773,305
Ensembl chr 8:22,750,336...22,774,903
JBrowse link
G Lep leptin IDA RGD PMID:21086559 RGD:5128549 NCBI chr 4:56,337,695...56,351,818
Ensembl chr 4:56,337,695...56,351,818
JBrowse link
G Lig3 DNA ligase 3 IEP protein:increased expression:brain RGD PMID:17412650 RGD:2302580 NCBI chr10:70,134,734...70,158,051
Ensembl chr10:70,134,729...70,158,055
JBrowse link
G Manf mesencephalic astrocyte-derived neurotrophic factor IEP protein:increased expression:brain RGD PMID:19773801 RGD:2325809 NCBI chr 8:115,623,175...115,626,408
Ensembl chr 8:115,623,178...115,626,380
JBrowse link
G Map2 microtubule-associated protein 2 IEP protein:increased expression:serum RGD PMID:21948028 RGD:6483082 NCBI chr 9:73,204,753...73,462,965
Ensembl chr 9:73,319,710...73,462,972
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 IDA
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:20302854, PMID:16699462 RGD:1582310 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Mapk8ip3 mitogen-activated protein kinase 8 interacting protein 3 IDA protein:increased activity:hippocampus RGD PMID:16805806 RGD:2293339 NCBI chr10:14,259,394...14,299,276
Ensembl chr10:14,260,787...14,299,167
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19667931, PMID:20302854 NCBI chr10:35,333,859...35,374,364
Ensembl chr10:35,333,859...35,374,355
JBrowse link
G Mb myoglobin ISO RGD PMID:12788661 RGD:1582427 NCBI chr 7:118,101,633...118,108,864
Ensembl chr 7:118,101,634...118,108,864
JBrowse link
G Mbl1 mannose binding lectin 1 ISO protein:decreased expression:serum RGD PMID:16982912, PMID:15509537 RGD:1582132, RGD:6903263 NCBI chr16:18,736,154...18,742,193
Ensembl chr16:18,736,154...18,742,193
JBrowse link
G Mbl2 mannose binding lectin 2 ISO protein:increased expression:serum RGD PMID:15882434, PMID:15509537 RGD:6903262, RGD:6903263 NCBI chr 1:248,435,069...248,442,669
Ensembl chr 1:248,723,397...248,729,962
JBrowse link
G Mc1r melanocortin 1 receptor no_association ISO RGD PMID:18757499 RGD:5687323 NCBI chr19:56,215,420...56,219,987 JBrowse link
G Mdk midkine ISO RGD PMID:15780085 RGD:1582475 NCBI chr 3:80,841,003...80,843,895
Ensembl chr 3:80,841,005...80,842,916
JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase IEP mRNA:increased expression:retina (rat) RGD PMID:17113948 RGD:2317505 NCBI chr 4:44,747,467...44,854,628
Ensembl chr 4:44,774,741...44,852,665
JBrowse link
G Mif macrophage migration inhibitory factor disease_progression ISO RGD PMID:18055556 RGD:4891010 NCBI chr20:13,715,219...13,732,980
Ensembl chr20:13,732,198...13,732,859
JBrowse link
G Mir148b microRNA 148b ISO CTD Direct Evidence: marker/mechanism CTD PMID:30308185 NCBI chr 7:144,912,038...144,912,134
Ensembl chr 7:144,912,038...144,912,134
JBrowse link
G Mmp3 matrix metallopeptidase 3 IEP protein:increased protein, activity:brain RGD PMID:15099024 RGD:2325962 NCBI chr 8:5,676,608...5,698,579
Ensembl chr 8:5,676,665...5,698,579
JBrowse link
G Mmp9 matrix metallopeptidase 9 ISO
IMP
IEP
CTD Direct Evidence: marker/mechanism
associated with lung injury; mRNA, protein:increased expression:lung
CTD PMID:23075401, PMID:16551680, PMID:19545667, PMID:16251419 RGD:1582618, RGD:5129531, RGD:1582631 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Mpo myeloperoxidase IEP
ISO
protein:increased activity:lung
CTD Direct Evidence: marker/mechanism
CTD PMID:8869312, PMID:10706834, PMID:12024109, PMID:16971220, PMID:19058328, PMID:20863214, PMID:21470877 RGD:5130958 NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
JBrowse link
G Mt-atp6 mitochondrially encoded ATP synthase membrane subunit 6 IEP RGD PMID:20450733 RGD:5490294 NCBI chr MT:7,919...8,599
Ensembl chr MT:7,919...8,599
JBrowse link
G Mt-atp8 mitochondrially encoded ATP synthase membrane subunit 8 IEP RGD PMID:20450733 RGD:5490294 NCBI chr MT:7,758...7,961
Ensembl chr MT:7,758...7,961
JBrowse link
G Mt-cyb mitochondrially encoded cytochrome b IEP mRNA:decreased expression:kidney RGD PMID:7692737 RGD:2298967 NCBI chr MT:14,136...15,278
Ensembl chr MT:14,136...15,278
JBrowse link
G Mt2A metallothionein 2A ISO mRNA:increased expression:cerebrum (mouse) RGD PMID:12122050 RGD:6483850 NCBI chr19:11,307,966...11,308,740
Ensembl chr19:11,307,967...11,308,740
JBrowse link
G Mt3 metallothionein 3 ISO RGD PMID:19635467 RGD:6480529 NCBI chr19:11,324,708...11,326,112
Ensembl chr19:11,324,698...11,326,139
JBrowse link
G Muc1 mucin 1, cell surface associated IEP RGD PMID:23977093 RGD:7349380 NCBI chr 2:188,543,137...188,547,874
Ensembl chr 2:188,543,137...188,547,874
JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:25780291 NCBI chr 8:128,022,512...128,027,462
Ensembl chr 8:128,022,473...128,026,841
JBrowse link
G Nes nestin IEP protein:increased expression:cerebral cortex RGD PMID:17569338 RGD:1642074 NCBI chr 2:187,343,109...187,352,972
Ensembl chr 2:187,344,056...187,352,969
JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 IEP protein:increased expression:small intestine RGD PMID:20107953 RGD:5131440 NCBI chr19:19,342,061...19,389,366
Ensembl chr19:19,332,594...19,377,492
JBrowse link
G Nos1 nitric oxide synthase 1 IMP RGD PMID:17451676 RGD:1642142 NCBI chr12:44,214,949...44,405,530
Ensembl chr12:44,213,943...44,520,341
JBrowse link
G Nos2 nitric oxide synthase 2 IEP
ISO
mRNA:increased expression:liver
CTD Direct Evidence: marker/mechanism
protein:increased expression:venule, arteriole, endothelium (mouse)
mRNA, protein:increased expression:liver
CTD PMID:10383581, PMID:19673871, PMID:23061969, PMID:23075401, PMID:11592783, PMID:22019501, PMID:14599979 RGD:2325259, RGD:5509100, RGD:1580938 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Nos3 nitric oxide synthase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21968084 NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410
JBrowse link
G Nox4 NADPH oxidase 4 IEP mRNA:increased expression:cerebral cortex RGD PMID:18438942 RGD:2324666 NCBI chr 1:150,796,359...150,976,186
Ensembl chr 1:150,797,084...150,976,194
JBrowse link
G Oga O-GlcNAcase IMP RGD PMID:16899550 RGD:2305957 NCBI chr 1:265,506,752...265,542,452
Ensembl chr 1:265,507,451...265,542,276
JBrowse link
G Oprm1 opioid receptor, mu 1 IEP mRNA, protein:decreased expression:hippocampus RGD PMID:17360495 RGD:2316611 NCBI chr 1:43,454,803...43,704,948
Ensembl chr 1:43,454,803...43,704,948
JBrowse link
G Otc ornithine carbamoyltransferase IEP protein:increased activity:serum RGD PMID:1499453 RGD:4144083 NCBI chr  X:13,524,804...13,601,074
Ensembl chr  X:13,524,607...13,601,069
JBrowse link
G Oxt oxytocin/neurophysin I prepropeptide IMP RGD PMID:18403049 RGD:2304111 NCBI chr 3:123,106,694...123,107,534
Ensembl chr 3:123,106,694...123,107,534
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 ISO
IEP
CTD Direct Evidence: marker/mechanism
protein:increased expression:liver (rat)
CTD PMID:15696051, PMID:16798486, PMID:9390645, PMID:21850691 RGD:5510018, RGD:5510020 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Pcsk2 proprotein convertase subtilisin/kexin type 2 IEP
ISO
RGD PMID:19142196, PMID:19142196 RGD:6483555, RGD:6483555 NCBI chr 3:137,618,891...137,923,385
Ensembl chr 3:137,618,898...137,925,605
JBrowse link
G Pde5a phosphodiesterase 5A IMP RGD PMID:19474186 RGD:2314462 NCBI chr 2:226,899,604...227,044,916
Ensembl chr 2:226,900,619...227,041,576
JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 IMP
IEP
ISO
protein:decreased expression:lung (rat)
protein:increased expression:brain (mouse)
RGD PMID:12121711, PMID:21872880, PMID:22382321 RGD:2311660, RGD:6771206, RGD:6766379 NCBI chr10:94,850,971...94,913,202 JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 IEP proetin:decreased dimerization:skeletal muscle (rat) RGD PMID:19100383 RGD:4108481 NCBI chr 2:31,742,326...31,826,882
Ensembl chr 2:31,745,088...31,826,867
JBrowse link
G Pklr pyruvate kinase L/R IEP RGD PMID:17013507 RGD:1625588 NCBI chr 2:188,449,158...188,458,034
Ensembl chr 2:188,449,210...188,459,592
JBrowse link
G Pla2g2a phospholipase A2 group IIA ISO CTD Direct Evidence: marker/mechanism CTD PMID:12967936 NCBI chr 5:157,282,650...157,285,295
Ensembl chr 5:157,282,669...157,285,328
JBrowse link
G Pla2g4a phospholipase A2 group IVA IDA protein:increased activity:alveolar macrophage RGD PMID:1642455 RGD:1642456 NCBI chr13:67,062,252...67,206,688
Ensembl chr13:66,988,937...67,206,693
JBrowse link
G Plat plasminogen activator, tissue type IDA
ISO
CTD Direct Evidence: therapeutic CTD PMID:9472885, PMID:15223382 RGD:2311674 NCBI chr16:74,098,263...74,122,897
Ensembl chr16:74,098,260...74,122,889
JBrowse link
G Plau plasminogen activator, urokinase IEP
ISO
protein:increased expression:spinal cord (rat)
CTD Direct Evidence: therapeutic
CTD PMID:15181847, PMID:19663807, PMID:18586014 RGD:6483808, RGD:6483830 NCBI chr15:3,644,296...3,650,765
Ensembl chr15:3,644,769...3,650,819
JBrowse link
G Plaur plasminogen activator, urokinase receptor ISO RGD PMID:18606671 RGD:6483829 NCBI chr 1:81,328,171...81,344,954
Ensembl chr 1:81,328,183...81,344,708
JBrowse link
G Pld2 phospholipase D2 IEP protein:increased expression:hippocampus CA1, hippocampus granule cell layer
mRNA:decreased expression:brainstem, cerebellum
RGD PMID:17393174, PMID:17024567 RGD:2299901, RGD:2299902 NCBI chr10:57,161,921...57,181,148
Ensembl chr10:57,163,174...57,179,730
JBrowse link
G Pnmt phenylethanolamine-N-methyltransferase ISO protein:increased expression:medulla oblongata (human) RGD PMID:21061149 RGD:5128821 NCBI chr10:86,340,893...86,342,501
Ensembl chr10:86,340,940...86,342,858
JBrowse link
G Polb DNA polymerase beta IEP protein:increased expression:cerebral cortex RGD PMID:17412650 RGD:2302580 NCBI chr16:74,237,001...74,260,272
Ensembl chr16:74,237,001...74,260,271
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha IDA
ISO
liver ischemia/reperfusion injury
CTD Direct Evidence: therapeutic
CTD PMID:19151258, PMID:21305343 RGD:5509942 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma ISO CTD Direct Evidence: therapeutic CTD PMID:12468449, PMID:24011919, PMID:24433871 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Ppp3ca protein phosphatase 3 catalytic subunit alpha IDA RGD PMID:14762344 RGD:1580702 NCBI chr 2:241,909,332...242,186,861
Ensembl chr 2:241,909,832...242,184,854
JBrowse link
G Ppp3cb protein phosphatase 3 catalytic subunit beta ISO RGD PMID:14615291 RGD:1580705 NCBI chr15:4,209,702...4,236,895
Ensembl chr15:4,209,703...4,236,895
JBrowse link
G Prdx6 peroxiredoxin 6 ISO RGD PMID:16766642 RGD:1580710 NCBI chr13:79,077,567...79,088,113
Ensembl chr13:79,077,033...79,088,127
JBrowse link
G Prkca protein kinase C, alpha IMP RGD PMID:17905752 RGD:2292474 NCBI chr10:96,186,509...96,585,168
Ensembl chr10:96,191,133...96,584,947
JBrowse link
G Prss1 serine protease 1 IEP RGD PMID:11062314 RGD:1599961 NCBI chr 4:70,776,046...70,779,249
Ensembl chr 4:70,776,046...70,779,249
JBrowse link
G Ptafr platelet-activating factor receptor treatment ISO
IMP
RGD PMID:12812996, PMID:11139461 RGD:1581279, RGD:10043168 NCBI chr 5:150,746,284...150,775,675
Ensembl chr 5:150,754,021...150,775,672
JBrowse link
G Pten phosphatase and tensin homolog IMP
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:19038262, PMID:17239858 RGD:2292538 NCBI chr 1:251,421,814...251,487,634
Ensembl chr 1:251,421,596...251,487,832
JBrowse link
G Ptges prostaglandin E synthase IEP
ISO
RGD PMID:12431630, PMID:16864802 RGD:2300116, RGD:2300094 NCBI chr 3:9,727,408...9,738,752
Ensembl chr 3:9,727,408...9,738,752
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:10594344, PMID:16385084 RGD:5688223 NCBI chr 3:15,560,685...15,582,339
Ensembl chr 3:15,560,712...15,582,344
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 IEP
ISO
IMP
IDA
protein:decreased expression:kidney
CTD Direct Evidence: marker/mechanism
CTD PMID:10588920, PMID:10594344, PMID:11567657, PMID:16386242, PMID:18258783, PMID:19673871, PMID:21394482, PMID:21944479, PMID:16247333 RGD:5135045, RGD:5508180, RGD:1580660 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Ptk2 protein tyrosine kinase 2 IEP protein:increased tyrosine phosphorylation:kidney RGD PMID:17620366 RGD:2292577 NCBI chr 7:114,436,419...114,611,317
Ensembl chr 7:114,437,361...114,590,119
JBrowse link
G Ptk2b protein tyrosine kinase 2 beta IDA protein:increased phosphorylation:hippocampus RGD PMID:15970382 RGD:1642621 NCBI chr15:42,827,306...42,947,796
Ensembl chr15:42,827,310...42,947,656
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit IEP
ISO
protein:increased expression:nucleus, liver
CTD Direct Evidence: marker/mechanism
CTD PMID:20302854, PMID:23743330, PMID:18621400 RGD:2298777 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G S100b S100 calcium binding protein B IEP RGD PMID:18840784 RGD:5508834 NCBI chr20:13,130,633...13,142,856
Ensembl chr20:13,130,636...13,142,856
JBrowse link
G S1pr1 sphingosine-1-phosphate receptor 1 ISO RGD PMID:16403835 RGD:1580913 NCBI chr 2:218,654,406...218,658,761
Ensembl chr 2:218,654,554...218,658,761
JBrowse link
G Scfd1 sec1 family domain containing 1 IEP protein:increased expression:cerebral cortex RGD PMID:9195952 RGD:633771 NCBI chr 6:72,124,408...72,202,703
Ensembl chr 6:72,124,417...72,202,713
JBrowse link
G Sele selectin E IEP
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:17112405, PMID:23743330, PMID:19489247 RGD:2313598 NCBI chr13:82,355,234...82,365,323
Ensembl chr13:82,355,471...82,365,341
JBrowse link
G Sell selectin L IEP RGD PMID:19489247 RGD:2313598 NCBI chr13:82,369,820...82,387,774
Ensembl chr13:82,369,493...82,387,631
JBrowse link
G Selp selectin P IEP
ISO
RGD PMID:18521901, PMID:21701413 RGD:2312314, RGD:6218990 NCBI chr13:82,428,914...82,464,629
Ensembl chr13:82,429,063...82,464,628
JBrowse link
G Serpine2 serpin family E member 2 IEP RGD PMID:8261109 RGD:2317936 NCBI chr 9:85,560,852...85,629,410
Ensembl chr 9:85,560,863...85,626,094
JBrowse link
G Serping1 serpin family G member 1 treatment ISO RGD PMID:23991040 RGD:8661644 NCBI chr 3:72,161,230...72,171,109
Ensembl chr 3:72,161,189...72,171,078
JBrowse link
G Sftpc surfactant protein C IDA mRNA:decreased expression:lung RGD PMID:20560845 RGD:4144062 NCBI chr15:52,211,538...52,214,480
Ensembl chr15:52,211,544...52,214,616
JBrowse link
G Si sucrase-isomaltase IEP RGD PMID:9724271 RGD:1625550 NCBI chr 2:170,220,794...170,301,348
Ensembl chr 2:170,221,245...170,301,348
JBrowse link
G Sirt7 sirtuin 7 ISO CTD Direct Evidence: therapeutic CTD PMID:28675767 NCBI chr10:109,796,046...109,802,821
Ensembl chr10:109,796,020...109,802,739
JBrowse link
G Slc2a1 solute carrier family 2 member 1 IEP mRNA, protein:increased expression:brain RGD PMID:19781384 RGD:2313601 NCBI chr 5:138,154,677...138,182,897
Ensembl chr 5:138,154,673...138,182,897
JBrowse link
G Slc2a3 solute carrier family 2 member 3 IEP mRNA, protein:increased expression:brain RGD PMID:19781384 RGD:2313601 NCBI chr 4:155,549,991...155,626,018
Ensembl chr 4:155,408,233...155,631,856
JBrowse link
G Slc30a4 solute carrier family 30 member 4 IEP mRNA:increased expression:brain RGD PMID:18289514 RGD:2299950 NCBI chr 3:114,805,919...114,828,154
Ensembl chr 3:114,805,922...114,828,154
JBrowse link
G Slc34a1 solute carrier family 34 member 1 IEP protein:decreased expression:renal proximal tubule RGD PMID:15775707 RGD:2311304 NCBI chr17:9,747,766...9,762,739
Ensembl chr17:9,747,752...9,762,813
JBrowse link
G Slc6a11 solute carrier family 6 member 11 IEP RGD PMID:13678673 RGD:1299345 NCBI chr 4:146,106,386...146,223,228
Ensembl chr 4:146,106,386...146,223,228
JBrowse link
G Slc8a1 solute carrier family 8 member A1 IEP RGD PMID:18037393 RGD:2316975 NCBI chr 6:4,244,076...4,564,262
Ensembl chr 6:4,258,991...4,520,604
JBrowse link
G Slc8a2 solute carrier family 8 member A2 IEP RGD PMID:18037393 RGD:2316975 NCBI chr 1:78,029,555...78,054,042
Ensembl chr 1:78,025,995...78,060,111
JBrowse link
G Slc8a3 solute carrier family 8 member A3 IEP RGD PMID:18037393 RGD:2316975 NCBI chr 6:104,889,500...105,099,408
Ensembl chr 6:104,891,376...105,097,054
JBrowse link
G Slc9a1 solute carrier family 9 member A1 IMP
ISO
CTD Direct Evidence: therapeutic CTD PMID:19027022, PMID:20337040 RGD:6771332 NCBI chr 5:151,573,122...151,626,360
Ensembl chr 5:151,573,092...151,627,316
JBrowse link
G Slco1b2 solute carrier organic anion transporter family member 1B2 IEP mRNA:decreased expression:liver RGD PMID:16858290 RGD:2303111 NCBI chr 4:175,814,118...175,881,775
Ensembl chr 4:175,814,118...175,881,768
JBrowse link
G Slk STE20-like kinase IEP protein:increased expression:kidney RGD PMID:12965890 RGD:2304069 NCBI chr 1:267,359,761...267,415,735
Ensembl chr 1:267,359,830...267,412,810
JBrowse link
G Slpi secretory leukocyte peptidase inhibitor ISO CTD Direct Evidence: therapeutic CTD PMID:8215636 NCBI chr 3:160,799,979...160,802,228
Ensembl chr 3:160,799,981...160,802,433
JBrowse link
G Socs1 suppressor of cytokine signaling 1 ISO CTD Direct Evidence: therapeutic CTD PMID:25780291 NCBI chr10:4,956,795...4,958,472
Ensembl chr10:4,957,326...4,958,461
JBrowse link
G Socs3 suppressor of cytokine signaling 3 IDA associated with Brain Ischemia;mRNA, protein:increased expression:cerebral cortex RGD PMID:12437578 RGD:632385 NCBI chr10:106,973,863...106,976,969
Ensembl chr10:106,975,178...106,976,040
JBrowse link
G Socs4 suppressor of cytokine signaling 4 IEP mRNA:increased expression:hippocampus RGD PMID:17880360 RGD:2303397 NCBI chr15:24,056,383...24,070,868
Ensembl chr15:24,056,383...24,070,857
JBrowse link
G Sod1 superoxide dismutase 1 ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:15364863, PMID:16397181, PMID:23061969, PMID:23743330, PMID:15364863 RGD:1580834 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
G Sod2 superoxide dismutase 2 IEP
ISO
protein:increased expression:liver
CTD Direct Evidence: marker/mechanism|therapeutic
CTD PMID:8215636, PMID:16682413, PMID:19193722, PMID:19917352, PMID:21940958, PMID:23743330, PMID:15612529, PMID:15087276 RGD:1582141, RGD:1581259 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Sod3 superoxide dismutase 3 ISO RGD PMID:15778274 RGD:1581264 NCBI chr14:60,958,583...60,971,143
Ensembl chr14:60,958,592...60,964,324
JBrowse link
G Spp1 secreted phosphoprotein 1 ISO RGD PMID:20548025 RGD:6903275 NCBI chr14:6,673,686...6,679,965
Ensembl chr14:6,673,686...6,679,901
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase IEP protein:increased phosphorylation:hippocampus CA1 (rat) RGD PMID:20197063 RGD:2325012 NCBI chr 3:153,547,807...153,595,643
Ensembl chr 3:153,580,861...153,595,642
JBrowse link
G Stat1 signal transducer and activator of transcription 1 IDA
IEP
protein:increased serine phosphorylation:brain
protein:increased phosphorylation:kidney
RGD PMID:15262323, PMID:17670769 RGD:1600103, RGD:2291900 NCBI chr 9:54,287,540...54,327,958
Ensembl chr 9:54,287,541...54,484,533
JBrowse link
G Stat2 signal transducer and activator of transcription 2 IEP mRNA:increased expression:hippocampus RGD PMID:17880360 RGD:2303397 NCBI chr 7:2,691,064...2,707,530
Ensembl chr 7:2,691,369...2,707,741
JBrowse link
G Stat3 signal transducer and activator of transcription 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21940958 NCBI chr10:88,790,401...88,842,263
Ensembl chr10:88,790,408...88,842,233
JBrowse link
G Stat5a signal transducer and activator of transcription 5A IEP mRNA:increased expression:hippocampus RGD PMID:17880360 RGD:2303397 NCBI chr10:88,764,732...88,789,060
Ensembl chr10:88,764,732...88,789,057
JBrowse link
G Stat5b signal transducer and activator of transcription 5B IEP mRNA:increased expression:hippocampus RGD PMID:17880360 RGD:2303397 NCBI chr10:88,686,207...88,712,313
Ensembl chr10:88,686,207...88,754,829
JBrowse link
G Stat6 signal transducer and activator of transcription 6 IEP mRNA:increased expression:hippocampus RGD PMID:17880360 RGD:2303397 NCBI chr 7:70,946,228...70,963,542
Ensembl chr 7:70,946,228...70,964,484
JBrowse link
G Stc1 stanniocalcin 1 IEP mRNA:increased expression:cerebral cortex RGD PMID:15485913 RGD:2324700 NCBI chr15:50,891,137...50,901,791
Ensembl chr15:50,891,127...50,903,162
JBrowse link
G Stc2 stanniocalcin 2 IEP mRNA, protein:increased expression:cerebral cortex RGD PMID:15485913 RGD:2324700 NCBI chr10:16,542,909...16,552,675
Ensembl chr10:16,542,882...16,553,295
JBrowse link
G Sult1e1 sulfotransferase family 1E member 1 IEP
ISO
protein:increased expression:serum
CTD Direct Evidence: marker/mechanism
CTD PMID:25922074, PMID:16908442 RGD:2302564 NCBI chr14:22,070,861...22,089,264
Ensembl chr14:22,072,024...22,089,248
JBrowse link
G Tbxas1 thromboxane A synthase 1 IDA associated with Cholestasis, Extrahepatic RGD PMID:15000260, PMID:8680115 RGD:1601451, RGD:1601475 NCBI chr 4:66,624,181...66,846,745
Ensembl chr 4:66,670,618...66,846,805
JBrowse link
G Tert telomerase reverse transcriptase ISO CTD Direct Evidence: marker/mechanism CTD PMID:16968891 NCBI chr 1:32,250,876...32,275,330
Ensembl chr 1:32,251,714...32,272,476
JBrowse link
G Tfam transcription factor A, mitochondrial IDA RGD PMID:22266265 RGD:6767573 NCBI chr20:18,594,057...18,606,106
Ensembl chr20:18,594,037...18,606,151
JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 IEP RGD PMID:15613744 RGD:1579926 NCBI chr 8:124,310,288...124,399,345
Ensembl chr 8:124,312,754...124,399,494
JBrowse link
G Th tyrosine hydroxylase ISO protein:increased expression:medulla oblongata (human) RGD PMID:21061149 RGD:5128821 NCBI chr 1:216,073,034...216,080,287
Ensembl chr 1:216,073,031...216,080,287
JBrowse link
G Thbd thrombomodulin ISO RGD PMID:19342415 RGD:5131887 NCBI chr 3:142,748,673...142,752,325
Ensembl chr 3:142,748,674...142,752,325
JBrowse link
G Thbs1 thrombospondin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16526316 NCBI chr 3:109,862,120...109,873,466
Ensembl chr 3:109,862,117...109,873,466
JBrowse link
G Thy1 Thy-1 cell surface antigen ISO CTD Direct Evidence: marker/mechanism CTD PMID:23075401 NCBI chr 8:48,382,121...48,387,271
Ensembl chr 8:48,382,121...48,386,935
JBrowse link
G Ticam1 toll-like receptor adaptor molecule 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25780291 NCBI chr 9:10,780,185...10,790,280 JBrowse link
G Timp3 TIMP metallopeptidase inhibitor 3 IEP protein:decreased expression:brain RGD PMID:17551674 RGD:2290424 NCBI chr 7:23,543,125...23,594,170
Ensembl chr 7:23,544,215...23,594,133
JBrowse link
G Tjp1 tight junction protein 1 IEP protein:decreased expression:brain, endothelial cell RGD PMID:19374856, PMID:19929946 RGD:2325135, RGD:2325127 NCBI chr 1:126,146,489...126,515,359
Ensembl chr 1:126,146,489...126,227,469
JBrowse link
G Tlr2 toll-like receptor 2 IEP
ISO
mRNA, protein:increased expression:kidney
CTD Direct Evidence: marker/mechanism
CTD PMID:25780291, PMID:15912106 RGD:2312727 NCBI chr 2:182,840,171...182,846,061
Ensembl chr 2:182,840,727...182,846,061
JBrowse link
G Tlr3 toll-like receptor 3 IEP protein:increased expression:liver (rat) RGD PMID:21355876 RGD:5128693 NCBI chr16:50,016,466...50,031,011
Ensembl chr16:50,016,857...50,031,214
JBrowse link
G Tlr4 toll-like receptor 4 IEP
ISO
protein:increased expression:liver
CTD Direct Evidence: marker/mechanism
CTD PMID:25780291, PMID:27064547, PMID:19473433, PMID:17126102 RGD:2312503, RGD:4144169 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052
JBrowse link
G Tmbim6 transmembrane BAX inhibitor motif containing 6 IEP protein:increased expression:liver RGD PMID:18005084 RGD:2291961 NCBI chr 7:141,039,433...141,070,269
Ensembl chr 7:141,034,982...141,069,989
JBrowse link
G Tnf tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:10706834, PMID:12024109, PMID:15829914, PMID:16971220, PMID:17112405, PMID:18460982, PMID:19058328, PMID:23743330, PMID:23875703, PMID:24898700 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A IEP RGD PMID:17109621 RGD:1624182 NCBI chr 4:157,864,905...157,877,634
Ensembl chr 4:157,864,969...157,877,633
JBrowse link
G Tp53 tumor protein p53 IEP protein:increased expression:brain, mitochondrion RGD PMID:17661174 RGD:2290568 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Trpc6 transient receptor potential cation channel, subfamily C, member 6 treatment IDA RGD PMID:20554625 RGD:4891135 NCBI chr 8:6,811,543...6,917,534
Ensembl chr 8:6,811,543...6,917,535
JBrowse link
G Trpm7 transient receptor potential cation channel, subfamily M, member 7 IEP mRNA,protein:increased expression:hippocampus RGD PMID:18395621 RGD:5684390 NCBI chr 3:119,258,189...119,347,084
Ensembl chr 3:119,259,467...119,330,345
JBrowse link
G Txn1 thioredoxin 1 IEP mRNA:decreased expression:cerebral cortex RGD PMID:19128823 RGD:5685030 NCBI chr 5:75,049,735...75,057,731
Ensembl chr 5:75,049,747...75,057,752
JBrowse link
G Txn2 thioredoxin 2 IEP mRNA:decreased expression:cerebral cortex RGD PMID:19128823 RGD:5685030 NCBI chr 7:119,144,350...119,158,173
Ensembl chr 7:119,144,351...119,158,201
JBrowse link
G Txnrd1 thioredoxin reductase 1 IEP mRNA:decreased expression:cerebral cortex
mRNA:decreased expression:spinal cord
RGD PMID:19128823, PMID:19409971 RGD:5685030, RGD:5685028 NCBI chr 7:26,946,124...26,984,400
Ensembl chr 7:26,946,125...26,984,400
JBrowse link
G Txnrd2 thioredoxin reductase 2 IEP mRNA:decreased expression:cerebral cortex RGD PMID:19128823 RGD:5685030 NCBI chr11:86,667,994...86,716,063
Ensembl chr11:86,667,997...86,716,254
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 IEP mRNA:increased expression:kidney RGD PMID:18813897 RGD:2313108 NCBI chr 2:219,071,193...219,090,931
Ensembl chr 2:219,071,193...219,097,619
JBrowse link
G Vegfc vascular endothelial growth factor C IEP RGD PMID:18704465 RGD:2315487 NCBI chr16:40,440,371...40,555,178
Ensembl chr16:40,440,207...40,555,576
JBrowse link
G Vegfd vascular endothelial growth factor D ISO CTD Direct Evidence: marker/mechanism CTD PMID:16526316 NCBI chr  X:31,816,480...31,852,239
Ensembl chr  X:31,816,436...31,851,715
JBrowse link
G Vim vimentin ISO CTD Direct Evidence: marker/mechanism CTD PMID:23075401 NCBI chr17:80,882,715...80,891,200
Ensembl chr17:80,882,666...80,891,212
JBrowse link
G Vip vasoactive intestinal peptide ISO RGD PMID:21693218 RGD:5685379 NCBI chr 1:42,169,307...42,177,582
Ensembl chr 1:42,169,501...42,177,582
JBrowse link
G Wnt3a Wnt family member 3A ISO CTD Direct Evidence: therapeutic CTD PMID:23875703 NCBI chr10:45,598,898...45,643,151
Ensembl chr10:45,598,912...45,638,035
JBrowse link
G Xdh xanthine dehydrogenase treatment IDA
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:12910483, PMID:23403765 RGD:7247700 NCBI chr 6:25,149,570...25,211,273
Ensembl chr 6:25,149,235...25,211,494
JBrowse link
G Xrcc1 X-ray repair cross complementing 1 IEP protein:increased expression:brain RGD PMID:17412650 RGD:2302580 NCBI chr 1:81,412,635...81,441,680
Ensembl chr 1:81,413,353...81,441,678
JBrowse link
G Zfp354a zinc finger protein 354A IEP mRNA:decreased expression:kidney RGD PMID:8382778 RGD:1300202 NCBI chr10:36,586,495...36,600,172
Ensembl chr10:36,589,181...36,600,469
JBrowse link
Cardiac Allograft Vasculopathy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F3 coagulation factor III, tissue factor IEP RGD PMID:9916935 RGD:11341701 NCBI chr 2:225,310,686...225,322,281
Ensembl chr 2:225,310,624...225,322,272
JBrowse link
G Pdgfd platelet derived growth factor D ISO RGD PMID:19213942 RGD:9854642 NCBI chr 8:4,441,010...4,666,754
Ensembl chr 8:4,440,876...4,669,014
JBrowse link
Chronic Allograft Dysfunction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ager advanced glycosylation end product-specific receptor treatment IEP RGD PMID:22217518, PMID:23769041 RGD:7245568, RGD:8695995 NCBI chr20:4,363,152...4,366,079
Ensembl chr20:4,363,152...4,366,079
JBrowse link
G C3 complement C3 treatment IDA RGD PMID:25122638 RGD:11040803 NCBI chr 9:9,721,137...9,747,084
Ensembl chr 9:9,721,105...9,747,167
JBrowse link
G Cd40 CD40 molecule treatment IDA RGD PMID:22826618 RGD:11352297 NCBI chr 3:161,519,789...161,534,943
Ensembl chr 3:161,519,743...161,534,704
JBrowse link
G Cd40lg CD40 ligand treatment IDA liver RGD PMID:22826618 RGD:11352297 NCBI chr  X:159,703,703...159,714,886
Ensembl chr  X:159,703,578...159,716,562
JBrowse link
G F7 coagulation factor VII treatment ISO human protein in a rat model RGD PMID:12095034 RGD:11049508 NCBI chr16:81,824,610...81,834,923
Ensembl chr16:81,824,111...81,834,945
JBrowse link
G Hmgb1 high mobility group box 1 treatment IEP RGD PMID:22217518 RGD:7245568 NCBI chr12:7,082,529...7,090,246
Ensembl chr16:37,500,017...37,502,237
JBrowse link
G Mtor mechanistic target of rapamycin kinase treatment IDA RGD PMID:23985719 RGD:10041002 NCBI chr 5:165,263,813...165,373,967
Ensembl chr 5:165,263,800...165,373,967
JBrowse link
G Tnf tumor necrosis factor treatment IMP RGD PMID:24598936 RGD:10450586 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
Chronic Allograft Nephropathy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aco1 aconitase 1 IEP RGD PMID:20176611 RGD:11541086 NCBI chr 5:56,425,076...56,481,218
Ensembl chr 5:56,425,024...56,481,218
JBrowse link
G Alb albumin disease_progression ISO RGD PMID:24370342 RGD:11035281 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 ISO RGD PMID:17298994 RGD:7241819 NCBI chr10:70,869,516...70,871,066
Ensembl chr10:70,869,513...70,871,066
JBrowse link
G Clu clusterin treatment IEP RGD PMID:22494435 RGD:9068431 NCBI chr15:42,626,612...42,665,858
Ensembl chr15:42,640,146...42,665,857
JBrowse link
G Mmp3 matrix metallopeptidase 3 ISO RGD PMID:22845765 RGD:7241226 NCBI chr 8:5,676,608...5,698,579
Ensembl chr 8:5,676,665...5,698,579
JBrowse link
G Mmp7 matrix metallopeptidase 7 treatment IDA RGD PMID:18209025 RGD:9685339 NCBI chr 8:5,893,253...5,900,965
Ensembl chr 8:5,893,249...5,901,049
JBrowse link
G Pdgfa platelet derived growth factor subunit A IEP RGD PMID:11889420 RGD:11080974 NCBI chr12:17,734,141...17,756,186
Ensembl chr12:17,734,133...17,755,285
JBrowse link
G Pdgfb platelet derived growth factor subunit B IEP mRNA:increased expression:kidney: RGD PMID:15785371, PMID:11889420 RGD:10449491, RGD:11080974 NCBI chr 7:121,215,458...121,233,092
Ensembl chr 7:121,214,628...121,232,741
JBrowse link
G Pdgfra platelet derived growth factor receptor alpha IEP RGD PMID:11889420 RGD:11080974 NCBI chr14:35,527,926...35,581,130
Ensembl chr14:35,527,927...35,581,031
JBrowse link
G Pdgfrb platelet derived growth factor receptor beta IEP RGD PMID:11889420 RGD:11080974 NCBI chr18:56,364,586...56,406,381
Ensembl chr18:56,364,620...56,406,381
JBrowse link
G Plau plasminogen activator, urokinase ISO protein:increased secretion:T lymphocyte (human) RGD PMID:16387096 RGD:7241259 NCBI chr15:3,644,296...3,650,765
Ensembl chr15:3,644,769...3,650,819
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma ISO protein:increased expression:kidney: RGD PMID:16221712 RGD:13208600 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Serpine1 serpin family E member 1 treatment ISO protein:increased expression:kidney: RGD PMID:16221712, PMID:18192922 RGD:13208600, RGD:13208601 NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482
JBrowse link
Chronic Lung Allograft Dysfunction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Epas1 endothelial PAS domain protein 1 IEP mRNA:increased expression:lung RGD PMID:22305384 RGD:10395369 NCBI chr 6:10,306,508...10,385,239
Ensembl chr 6:10,306,405...10,387,265
JBrowse link
Gastric Reperfusion Injury term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kit KIT proto-oncogene receptor tyrosine kinase IEP mRNA,protein:decreased expression:stomach: RGD PMID:20040059 RGD:12911222 NCBI chr14:35,072,131...35,149,638
Ensembl chr14:35,072,108...35,149,610
JBrowse link
G Kitlg KIT ligand IEP mRNA:decreased expression:stomach: RGD PMID:20040059 RGD:12911222 NCBI chr 7:42,269,784...42,351,054
Ensembl chr 7:42,269,784...42,351,054
JBrowse link
Intestinal Reperfusion Injury term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme IEP RGD PMID:15001561 RGD:13515113 NCBI chr10:94,170,766...94,213,831
Ensembl chr10:94,170,766...94,187,822
JBrowse link
G Agt angiotensinogen IEP protein:increased expression:plasma RGD PMID:15001561 RGD:13515113 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433
JBrowse link
G Atp5f1d ATP synthase F1 subunit delta treatment IEP RGD PMID:24232000 RGD:13792678 NCBI chr 7:12,426,807...12,432,120
Ensembl chr 7:12,426,809...12,432,130
JBrowse link
G Casp3 caspase 3 treatment IEP RGD PMID:23946597 RGD:13782356 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp9 caspase 9 treatment IEP RGD PMID:23946597 RGD:13782356 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 IEP mRNA:increased expression:small intestine RGD PMID:18475188 RGD:2307016 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Cd14 CD14 molecule IEP protein:increased expression:heart, kidney, liver, lung RGD PMID:22493902 RGD:9685194 NCBI chr18:29,560,341...29,562,290
Ensembl chr18:29,560,365...29,562,153
JBrowse link
G Cldn1 claudin 1 IEP protein:decreased expression:colon: RGD PMID:19929946 RGD:2325127 NCBI chr11:77,815,216...77,830,373
Ensembl chr11:77,815,181...77,830,416
JBrowse link
G Cldn3 claudin 3 IEP protein:decreased expression:colon: RGD PMID:19929946 RGD:2325127 NCBI chr12:21,831,341...21,832,813
Ensembl chr12:21,831,342...21,832,813
JBrowse link
G Cldn5 claudin 5 IEP protein:decreased expression:colon: RGD PMID:19929946 RGD:2325127 NCBI chr11:86,356,292...86,357,718
Ensembl chr11:86,356,294...86,357,718
JBrowse link
G Crp C-reactive protein IEP protein:increased expression:intestine: RGD PMID:17981193 RGD:5129536 NCBI chr13:91,080,448...91,081,358
Ensembl chr13:91,054,974...91,093,713
JBrowse link
G Csf3 colony stimulating factor 3 treatment ISO RGD PMID:9117128 RGD:11039476 NCBI chr10:86,616,785...86,619,160
Ensembl chr10:86,616,785...86,619,157
JBrowse link
G F7 coagulation factor VII ISO human protein in a rat model RGD PMID:22920553 RGD:11041662 NCBI chr16:81,824,610...81,834,923
Ensembl chr16:81,824,111...81,834,945
JBrowse link
G Faslg Fas ligand treatment IEP RGD PMID:29170412 RGD:13792603 NCBI chr13:79,696,811...79,717,581
Ensembl chr13:79,698,445...79,705,705
JBrowse link
G Hmgb1 high mobility group box 1 IEP RGD PMID:22093738 RGD:10402181 NCBI chr12:7,082,529...7,090,246
Ensembl chr16:37,500,017...37,502,237
JBrowse link
G Hmox1 heme oxygenase 1 treatment IEP RGD PMID:19362701 RGD:10766423 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hp haptoglobin treatment IEP RGD PMID:11922743 RGD:11041790 NCBI chr19:42,096,255...42,100,805
Ensembl chr19:42,097,995...42,100,804
JBrowse link
G Icam1 intercellular adhesion molecule 1 IEP RGD PMID:12095141 RGD:11522715 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Il6 interleukin 6 treatment IDA RGD PMID:11959089 RGD:11062110 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Jak2 Janus kinase 2 IMP RGD PMID:22777122 RGD:10403072 NCBI chr 1:247,398,667...247,457,521
Ensembl chr 1:247,398,598...247,458,509
JBrowse link
G Lbp lipopolysaccharide binding protein IEP protein:increased expression:heart, kidney, liver, lung RGD PMID:22493902 RGD:9685194 NCBI chr 3:154,786,232...154,812,910
Ensembl chr 3:154,786,215...154,813,464
JBrowse link
G Mbl2 mannose binding lectin 2 severity ISO DNA:polymorphisms:exon: RGD PMID:19477015 RGD:12910933 NCBI chr 1:248,435,069...248,442,669
Ensembl chr 1:248,723,397...248,729,962
JBrowse link
G Mir155 microRNA 155 ISO miRNA:increased expression:Peyer's patch RGD PMID:30206757 RGD:21409753 NCBI chr11:24,176,603...24,176,667
Ensembl chr11:24,176,603...24,176,667
JBrowse link
G Nos3 nitric oxide synthase 3 treatment IDA RGD PMID:16610051 RGD:7777112 NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 treatment IEP RGD PMID:28382390 RGD:13440093 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 disease_progression IEP mRNA:decreased expression:liver (rat) RGD PMID:23331901 RGD:15042883 NCBI chr 7:30,003,429...30,162,095
Ensembl chr 7:30,003,429...30,162,056
JBrowse link
G Parg poly (ADP-ribose) glycohydrolase treatment IMP RGD PMID:15791006 RGD:13514040 NCBI chr16:8,350,168...8,457,999
Ensembl chr16:8,350,326...8,457,996
JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A ISO mRNA:increased expression:jejunum (human) RGD PMID:20965186 RGD:9999150 NCBI chr 1:101,511,899...101,515,043
Ensembl chr 1:101,511,901...101,514,974
JBrowse link
G Proc protein C, inactivator of coagulation factors Va and VIIIa treatment ISO RGD PMID:15187522 RGD:11250409 NCBI chr18:24,918,402...24,928,822
Ensembl chr18:24,918,398...24,929,091
JBrowse link
G Serpinc1 serpin family C member 1 treatment IEP RGD PMID:21046505 RGD:11035258 NCBI chr13:78,806,107...78,820,375
Ensembl chr13:78,805,347...78,833,192
JBrowse link
G Serpine1 serpin family E member 1 IDA protein:increased activity:plasma (rat) RGD PMID:12717359 RGD:11081012 NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482
JBrowse link
G Vwf von Willebrand factor IEP protein:increased expression:plasma: RGD PMID:10365842 RGD:11080742 NCBI chr 4:158,085,059...158,219,525
Ensembl chr 4:158,088,505...158,219,523
JBrowse link
G Xdh xanthine dehydrogenase treatment IEP RGD PMID:23010742 RGD:13209016 NCBI chr 6:25,149,570...25,211,273
Ensembl chr 6:25,149,235...25,211,494
JBrowse link
Kidney Reperfusion Injury term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme IMP RGD PMID:21680852 RGD:6893484 NCBI chr10:94,170,766...94,213,831
Ensembl chr10:94,170,766...94,187,822
JBrowse link
G Ace2 angiotensin I converting enzyme 2 IEP mRNA:decreased expression:kidney RGD PMID:20528771 RGD:9685432 NCBI chr  X:32,050,734...32,095,860
Ensembl chr  X:32,049,931...32,096,016
JBrowse link
G Adam17 ADAM metallopeptidase domain 17 treatment IEP RGD PMID:22015440 RGD:13703100 NCBI chr 6:43,400,525...43,448,280
Ensembl chr 6:43,400,528...43,448,280
JBrowse link
G Adam2 ADAM metallopeptidase domain 2 IEP RGD PMID:11967014 RGD:10047130 NCBI chr15:42,708,536...42,751,281
Ensembl chr15:42,708,387...42,751,330
JBrowse link
G Adamts1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 IEP RGD PMID:18272597 RGD:9684850 NCBI chr11:25,342,119...25,350,938
Ensembl chr11:25,342,126...25,350,974
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing treatment ISO RGD PMID:21412771 RGD:8695946 NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488
JBrowse link
G Adm adrenomedullin treatment IEP
ISO
protein:increased expression:serum: RGD PMID:20538296, PMID:20538296 RGD:7364948, RGD:7364948 NCBI chr 1:175,443,189...175,447,260
Ensembl chr 1:175,445,088...175,447,259
JBrowse link
G Akr1a1 aldo-keto reductase family 1 member A1 ISO RGD PMID:31089212 RGD:27226686 NCBI chr 5:135,482,068...135,498,693
Ensembl chr 5:135,482,068...135,498,822
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member ISO RGD PMID:22022451 RGD:7241603 NCBI chr12:40,466,418...40,498,813
Ensembl chr12:40,466,495...40,498,752
JBrowse link
G Anxa1 annexin A1 treatment IDA RGD PMID:20953576 RGD:7421585 NCBI chr 1:237,893,983...237,910,002
Ensembl chr 1:237,893,966...237,910,012
JBrowse link
G Anxa5 annexin A5 ISO RGD PMID:21918686 RGD:7242028 NCBI chr 2:123,162,477...123,194,730
Ensembl chr 2:123,162,461...123,193,130
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 treatment IEP RGD PMID:26362957 RGD:13703110 NCBI chr 7:31,699,309...31,784,192
Ensembl chr 7:31,699,885...31,784,192
JBrowse link
G Apoa1 apolipoprotein A1 treatment ISO RGD PMID:18535924 RGD:7241574 NCBI chr 8:50,525,091...50,526,875
Ensembl chr 8:50,525,091...50,526,875
JBrowse link
G Atm ATM serine/threonine kinase IEP protein:increased expression:kidney RGD PMID:22768306 RGD:10053607 NCBI chr 8:58,015,938...58,119,973
Ensembl chr 8:58,015,940...58,120,045
JBrowse link
G Bax BCL2 associated X, apoptosis regulator treatment IEP RGD PMID:23151253 RGD:10054101 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator treatment IEP RGD PMID:18221257, PMID:29285062 RGD:2293026, RGD:13792599 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bdkrb1 bradykinin receptor B1 ISO RGD PMID:18725957 RGD:7241559 NCBI chr 6:129,437,423...129,441,553
Ensembl chr 6:129,438,158...129,440,574
JBrowse link
G Becn1 beclin 1 treatment IEP RGD PMID:26412257 RGD:11561958 NCBI chr10:89,209,944...89,225,297
Ensembl chr10:89,209,940...89,225,297
JBrowse link
G Bnip3 BCL2 interacting protein 3 IEP mRNA, protein:increased expression:kidney RGD PMID:23698117 RGD:11561968 NCBI chr 1:211,248,098...211,265,282
Ensembl chr 1:211,248,098...211,265,282
JBrowse link
G C3 complement C3 treatment IEP RGD PMID:19691975 RGD:7411689 NCBI chr 9:9,721,137...9,747,084
Ensembl chr 9:9,721,105...9,747,167
JBrowse link
G Calca calcitonin-related polypeptide alpha IMP RGD PMID:19194162 RGD:7204479 NCBI chr 1:184,184,018...184,188,922
Ensembl chr 1:184,184,020...184,188,911
JBrowse link
G Casp3 caspase 3 treatment IEP RGD PMID:23151253 RGD:10054101 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp7 caspase 7 IEP RGD PMID:17596683 RGD:5684536 NCBI chr 1:277,190,557...277,242,779
Ensembl chr 1:277,190,964...277,242,774
JBrowse link
G Ccl11 C-C motif chemokine ligand 11 treatment ISO RGD PMID:22160777 RGD:7247742 NCBI chr10:69,434,965...69,439,566
Ensembl chr10:69,434,941...69,439,575
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 treatment ISO
IDA
mRNA, protein:increased expression:kidney, lung, serum RGD PMID:20396927, PMID:18650485 RGD:4891433, RGD:11526113 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Cd14 CD14 molecule ISO mRNA,protein:increased expression:kidney RGD PMID:10966493 RGD:7204444 NCBI chr18:29,560,341...29,562,290
Ensembl chr18:29,560,365...29,562,153
JBrowse link
G Cd40 CD40 molecule treatment IMP RGD PMID:25993320 RGD:11251055 NCBI chr 3:161,519,789...161,534,943
Ensembl chr 3:161,519,743...161,534,704
JBrowse link
G Cfb complement factor B ISO RGD PMID:16467447, PMID:12538716 RGD:7242709, RGD:7242734 NCBI chr20:4,536,206...4,542,073
Ensembl chr20:4,536,203...4,561,066
Ensembl chr20:4,536,203...4,561,066
JBrowse link
G Cfh complement factor H treatment IEP
ISO
protein:decreased expression:serum: RGD PMID:20538296, PMID:20538296 RGD:7364948, RGD:7364948 NCBI chr13:56,979,155...57,080,540
Ensembl chr13:56,978,607...57,080,622
JBrowse link
G Ciita class II, major histocompatibility complex, transactivator ISO RGD PMID:14569092 RGD:7242896 NCBI chr10:5,212,621...5,260,641
Ensembl chr10:5,213,350...5,260,608
JBrowse link
G Csf1 colony stimulating factor 1 ISO mRNA:increased expression:kidney RGD PMID:23143303, PMID:19196448 RGD:7257565, RGD:7257570 NCBI chr 2:210,522,370...210,550,546
Ensembl chr 2:210,522,375...210,550,560
JBrowse link
G Csf1r colony stimulating factor 1 receptor ISO RGD PMID:23143303 RGD:7257565 NCBI chr18:56,414,493...56,458,300
Ensembl chr18:56,414,488...56,458,300
JBrowse link
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 ISO RGD PMID:22189844, PMID:9407517 RGD:7204675, RGD:7204727 NCBI chr 9:67,699,397...67,706,068
Ensembl chr 9:67,699,379...67,706,065
JBrowse link
G Cxcr2 C-X-C motif chemokine receptor 2 ISO RGD PMID:20038794 RGD:7257679 NCBI chr 9:81,427,275...81,435,065
Ensembl chr 9:81,427,730...81,434,102
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 IEP protein:increased expression:kidney RGD PMID:29073721 RGD:13825150 NCBI chr13:45,314,952...45,318,856
Ensembl chr13:45,314,933...45,318,878
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 treatment IMP RGD PMID:23552495 RGD:7244372 NCBI chr 8:58,744,849...58,772,408
Ensembl chr 8:58,744,849...58,772,408
JBrowse link
G Daxx death-domain associated protein ISO protein:increased expression:kidney: RGD PMID:18480747, PMID:18480747 RGD:9587836, RGD:9587836 NCBI chr20:5,480,103...5,485,962
Ensembl chr20:5,480,103...5,485,926
JBrowse link
G Dhfr dihydrofolate reductase IEP mRNA,protein:decreased expression:kidney: RGD PMID:18408363 RGD:11040540 NCBI chr 2:21,931,887...21,958,927
Ensembl chr 2:21,931,493...21,962,453
JBrowse link
G Drd3 dopamine receptor D3 treatment IDA RGD PMID:25989500 RGD:13506961 NCBI chr11:61,819,102...61,883,223
Ensembl chr11:61,822,077...61,874,327
JBrowse link
G Egln1 egl-9 family hypoxia-inducible factor 1 IEP mRNA, protein:decreased expression:kidney RGD PMID:19349364 RGD:11252083 NCBI chr19:57,660,194...57,701,158
Ensembl chr19:57,662,278...57,699,113
JBrowse link
G Egln3 egl-9 family hypoxia-inducible factor 3 IEP mRNA, protein:decreased expression:kidney RGD PMID:19349364 RGD:11252083 NCBI chr 6:75,050,329...75,075,795
Ensembl chr 6:75,050,329...75,075,795
JBrowse link
G Elane elastase, neutrophil expressed treatment IMP RGD PMID:16980042 RGD:10450580 NCBI chr 7:12,638,320...12,640,168
Ensembl chr 7:12,638,322...12,640,232
JBrowse link
G Eng endoglin IEP
ISO
mRNA, protein:increased expression:kidney (rat) RGD PMID:16751653, PMID:16751653 RGD:7248779, RGD:7248779 NCBI chr 3:11,679,530...11,717,486
Ensembl chr 3:11,679,530...11,717,485
JBrowse link
G Ep300 E1A binding protein p300 IEP protein:altered localization:kidney (rat) RGD PMID:23936185 RGD:7257563 NCBI chr 7:122,818,194...122,889,055
Ensembl chr 7:122,818,975...122,861,296
JBrowse link
G Epo erythropoietin treatment ISO RGD PMID:19961832, PMID:25581532 RGD:10401077, RGD:11041698 NCBI chr12:22,274,828...22,278,268
Ensembl chr12:22,274,828...22,278,266
JBrowse link
G F3 coagulation factor III, tissue factor IEP protein:decreased expression:lung RGD PMID:25883098 RGD:11341735 NCBI chr 2:225,310,686...225,322,281
Ensembl chr 2:225,310,624...225,322,272
JBrowse link
G Fas Fas cell surface death receptor treatment IEP RGD PMID:29285062 RGD:13792599 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Faslg Fas ligand treatment IEP RGD PMID:29285062 RGD:13792599 NCBI chr13:79,696,811...79,717,581
Ensembl chr13:79,698,445...79,705,705
JBrowse link
G Fcgr1a Fc fragment of IgG receptor Ia treatment ISO RGD PMID:22402584 RGD:9685699 NCBI chr 2:198,430,536...198,439,453
Ensembl chr 2:198,430,530...198,458,041
JBrowse link
G Fga fibrinogen alpha chain IEP mRNA,protein:increased expression:kidney RGD PMID:21685370 RGD:7175292 NCBI chr 2:181,997,562...182,013,726
Ensembl chr 2:182,006,242...182,013,763
JBrowse link
G Fgb fibrinogen beta chain treatment IEP
ISO
mRNA, protein:increased expression:kidney RGD PMID:21685370, PMID:21685370 RGD:7175292, RGD:7175292 NCBI chr 2:182,028,044...182,035,026
Ensembl chr 2:182,027,115...182,038,178
JBrowse link
G Fgg fibrinogen gamma chain IEP mRNA,protein:increased expression:kidney RGD PMID:21685370 RGD:7175292 NCBI chr 2:181,987,080...181,994,523
Ensembl chr 2:181,987,217...181,994,514
JBrowse link
G Fn1 fibronectin 1 IEP RGD PMID:11352844 RGD:7205629 NCBI chr 9:78,900,111...78,969,018
Ensembl chr 9:78,900,103...78,969,078
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit ISO RGD PMID:19095962 RGD:7242184 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Gfer growth factor, augmenter of liver regeneration treatment IEP
ISO
protein:increased expression:kidney: RGD PMID:20332418, PMID:20332418 RGD:9685723, RGD:9685723 NCBI chr10:14,059,347...14,061,703
Ensembl chr10:14,059,347...14,061,703
JBrowse link
G Glo1 glyoxalase 1 IMP RGD PMID:19211689 RGD:7242566 NCBI chr20:9,273,589...9,291,608
Ensembl chr20:9,273,594...9,291,610
JBrowse link
G Gsr glutathione-disulfide reductase treatment IEP RGD PMID:24630969 RGD:10401866 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G H2ax H2A.X variant histone treatment IEP RGD PMID:23726287 RGD:8693706 NCBI chr 8:48,665,652...48,666,981
Ensembl chr 8:48,665,652...48,666,981
JBrowse link
G Has1 hyaluronan synthase 1 IEP RGD PMID:22529164 RGD:9588636 NCBI chr 1:59,720,612...59,732,409
Ensembl chr 1:59,720,612...59,732,409
JBrowse link
G Has2 hyaluronan synthase 2 IEP RGD PMID:22529164 RGD:9588636 NCBI chr 7:96,438,046...96,464,049
Ensembl chr 7:96,438,046...96,464,049
JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 IEP
ISO
protein:increased expression:urine: RGD PMID:23552495, PMID:23019274, PMID:23085062 RGD:7244372, RGD:7245495, RGD:7245489 NCBI chr10:31,813,819...31,860,934
Ensembl chr10:31,813,814...31,848,379
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha treatment
severity
IDA
IMP
RGD PMID:17519789, PMID:22432008 RGD:1626334, RGD:9068883 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Hmox1 heme oxygenase 1 treatment IMP RGD PMID:21291499 RGD:10755580 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hsf1 heat shock transcription factor 1 IEP protein:increased expression:kidney (rat) RGD PMID:23102208 RGD:10402775 NCBI chr 7:117,538,523...117,565,478
Ensembl chr 7:117,538,523...117,565,478
JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 IEP RGD PMID:7569112 RGD:7242788 NCBI chr 8:44,989,401...44,993,261
Ensembl chr 8:44,990,014...44,993,179
JBrowse link
G Hyal1 hyaluronidase 1 IEP RGD PMID:22529164 RGD:9588636 NCBI chr 8:116,332,834...116,337,522
Ensembl chr 8:116,332,796...116,335,435
JBrowse link
G Hyal2 hyaluronidase 2 IEP RGD PMID:22529164 RGD:9588636 NCBI chr 8:116,324,062...116,328,978
Ensembl chr 8:116,324,040...116,328,978
JBrowse link
G Ifng interferon gamma treatment ISO RGD PMID:28355607 RGD:14975115 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Igf1r insulin-like growth factor 1 receptor IEP mRNA: increased expression: kidney: 3 and 5 days post ischemia RGD PMID:10990448 RGD:7242905 NCBI chr 1:128,924,921...129,213,816
Ensembl chr 1:128,924,966...129,206,516
JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta treatment IMP RGD PMID:19546526 RGD:7495779 NCBI chr16:74,177,233...74,230,809
Ensembl chr16:74,177,215...74,230,815
JBrowse link
G Il10 interleukin 10 treatment IDA
ISO
RGD PMID:24079335, PMID:28664613 RGD:7364864, RGD:14975137 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il18 interleukin 18 treatment IMP RGD PMID:22089199 RGD:8655971 NCBI chr 8:55,009,666...55,016,286
Ensembl chr 8:54,993,859...55,016,299
JBrowse link
G Il1b interleukin 1 beta IDA RGD PMID:20030532 RGD:7175501 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il1rn interleukin 1 receptor antagonist ISO rat model treated with human protein
mouse model treated with human protein
RGD PMID:18363573, PMID:9555664, PMID:16849996 RGD:6907101, RGD:6909149, RGD:6907359 NCBI chr 3:1,449,778...1,468,624
Ensembl chr 3:1,452,644...1,468,614
JBrowse link
G Itgb2 integrin subunit beta 2 ISO
IMP
Associated with renal transplant patients RGD PMID:20504838, PMID:11007822 RGD:6907049, RGD:6907073 NCBI chr20:11,777,773...11,815,647
Ensembl chr20:11,777,783...11,815,647
JBrowse link
G Kcnj11 potassium inwardly-rectifying channel, subfamily J, member 11 IEP protein:decreased expression:kidney RGD PMID:21250976 RGD:7297045 NCBI chr 1:102,103,093...102,107,134
Ensembl chr 1:102,103,094...102,106,127
JBrowse link
G Kl Klotho treatment IEP
ISO
mRNA,protein:decreased expression:renal tubule: RGD PMID:16204278, PMID:16204278 RGD:10403064, RGD:10403064 NCBI chr12:942,974...987,206
Ensembl chr12:943,006...987,551
JBrowse link
G Lcn2 lipocalin 2 IEP
ISO
protein:increased expression:urine: RGD PMID:23364806, PMID:23085062 RGD:7245469, RGD:7245489 NCBI chr 3:11,414,189...11,417,534
Ensembl chr 3:11,414,186...11,417,546
JBrowse link
G Lep leptin resistance IDA RGD PMID:22969992 RGD:6909133 NCBI chr 4:56,337,695...56,351,818
Ensembl chr 4:56,337,695...56,351,818
JBrowse link
G Lgals3 galectin 3 IEP mRNA:increased expression:kidney RGD PMID:10980121 RGD:9685228 NCBI chr15:24,153,602...24,165,537
Ensembl chr15:24,141,651...24,165,537
JBrowse link
G Map1lc3a microtubule-associated protein 1 light chain 3 alpha treatment ISO
IEP
RGD PMID:20075199, PMID:26412257 RGD:11561916, RGD:11561958 NCBI chr 3:150,801,289...150,802,935
Ensembl chr 3:150,801,289...150,802,935
JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 treatment IMP RGD PMID:23952292 RGD:10412647 NCBI chr 1:15,412,603...15,613,752
Ensembl chr 1:15,412,603...15,613,746
JBrowse link
G Mc1r melanocortin 1 receptor IEP protein:decreased expression:kidney outer medulla RGD PMID:18790174 RGD:5687322 NCBI chr19:56,215,420...56,219,987 JBrowse link
G Mir381 microRNA 381 IEP RNA:decreased expression:kidney RGD PMID:29073721 RGD:13825150 NCBI chr 6:133,876,615...133,876,675
Ensembl chr 6:133,876,586...133,876,693
JBrowse link
G Mpo myeloperoxidase IEP
ISO
protein:increased activity:kidney RGD PMID:22950848, PMID:18055546 RGD:6909167, RGD:7174699 NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
JBrowse link
G Muc1 mucin 1, cell surface associated treatment IDA RGD PMID:22019164 RGD:7245959 NCBI chr 2:188,543,137...188,547,874
Ensembl chr 2:188,543,137...188,547,874
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor IEP mRNA:increased expression:kidney (rat) RGD PMID:17220792 RGD:7207777 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G Ndufb8 NADH:ubiquinone oxidoreductase subunit B8 IEP
ISO
RGD PMID:24096033, PMID:22160772 RGD:13801197, RGD:13801199 NCBI chr 1:264,298,671...264,303,712
Ensembl chr 1:264,298,669...264,303,762
JBrowse link
G Nes nestin IEP RGD PMID:24503548 RGD:11570523 NCBI chr 2:187,343,109...187,352,972
Ensembl chr 2:187,344,056...187,352,969
JBrowse link
G Nos3 nitric oxide synthase 3 treatment IEP RGD PMID:29291552 RGD:13504682 NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410
JBrowse link
G Nppa natriuretic peptide A ISO RGD PMID:20471588 RGD:7247717 NCBI chr 5:164,808,407...164,809,716
Ensembl chr 5:164,808,323...164,809,705
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 treatment IEP RGD PMID:21545725 RGD:11035217 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 severity ISO mRNA:increased expression:kidney RGD PMID:22343121, PMID:22343121 RGD:14700869, RGD:14700869 NCBI chr 7:142,899,358...142,920,216
Ensembl chr 7:142,905,758...142,920,216
JBrowse link
G Ogg1 8-oxoguanine DNA glycosylase IEP RGD PMID:12531391 RGD:2317150 NCBI chr 4:145,282,828...145,289,367
Ensembl chr 4:145,282,797...145,289,326
JBrowse link
G Pax2 paired box 2 IEP mRNA, protein:increased expression:kidney RGD PMID:12444203 RGD:727468 NCBI chr 1:264,493,579...264,585,073
Ensembl chr 1:264,504,591...264,583,329
JBrowse link
G Pdgfb platelet derived growth factor subunit B IEP mRNA,protein:increased expression:tubule, S3 segment: RGD PMID:10550325 RGD:8554477 NCBI chr 7:121,215,458...121,233,092
Ensembl chr 7:121,214,628...121,232,741
JBrowse link
G Pdgfra platelet derived growth factor receptor alpha IEP mRNA:increased expression:kidney RGD PMID:10550325 RGD:8554477 NCBI chr14:35,527,926...35,581,130
Ensembl chr14:35,527,927...35,581,031
JBrowse link
G Pdgfrb platelet derived growth factor receptor beta IMP
IEP
mRNA:increased expression:kidney RGD PMID:12819032, PMID:10550325 RGD:1580850, RGD:8554477 NCBI chr18:56,364,586...56,406,381
Ensembl chr18:56,364,620...56,406,381
JBrowse link
G Pkd2 polycystin 2, transient receptor potential cation channel IEP protein:increased expression:kidney (rat) RGD PMID:12454224 RGD:1580868 NCBI chr14:6,602,004...6,645,257
Ensembl chr14:6,602,004...6,645,257
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha treatment IDA RGD PMID:24918615 RGD:10059636 NCBI chr14:63,095,291...63,190,688
Ensembl chr14:63,095,720...63,187,009
JBrowse link
G Rnls renalase, FAD-dependent amine oxidase ISO mRNA,protein:decreased expression:kidney,plasma: RGD PMID:23393318, PMID:23393318 RGD:7327166, RGD:7327166 NCBI chr 1:251,828,285...252,101,963
Ensembl chr 1:251,828,290...252,100,759
JBrowse link
G Serpina1 serpin family A member 1 treatment ISO RGD PMID:28235038 RGD:14695051 NCBI chr 6:127,610,241...127,632,265
Ensembl chr 6:127,610,243...127,632,265
JBrowse link
G Serpinc1 serpin family C member 1 severity IMP RGD PMID:26108065 RGD:11354006 NCBI chr13:78,806,107...78,820,375
Ensembl chr13:78,805,347...78,833,192
JBrowse link
G Serpinc1em2Mcwi serpin family C member 1; ZFN induced mutant 2, Medical College of Wisconsin IMP RGD PMID:26108065 RGD:11354006
G Shh sonic hedgehog signaling molecule ISO mRNA, protein:increased expression:kidney RGD PMID:24744439 RGD:12859042 NCBI chr 4:718,538...727,691
Ensembl chr 4:718,538...727,691
JBrowse link
G Sirt1 sirtuin 1 treatment IEP RGD PMID:22324445 RGD:9495930 NCBI chr20:26,831,971...26,851,587
Ensembl chr20:26,833,357...26,852,199
JBrowse link
G Slc22a1 solute carrier family 22 member 1 IEP RGD PMID:21835768 RGD:7243877 NCBI chr 1:48,273,639...48,300,645
Ensembl chr 1:48,273,611...48,300,655
JBrowse link
G Slc22a2 solute carrier family 22 member 2 IEP RGD PMID:21835768 RGD:7243877 NCBI chr 1:48,318,025...48,360,219
Ensembl chr 1:48,317,995...48,360,261
JBrowse link
G Slc34a1 solute carrier family 34 member 1 IEP protein:decreased expression:renal proximal tubule, brush border membrane (rat) RGD PMID:15775707 RGD:2311304 NCBI chr17:9,747,766...9,762,739
Ensembl chr17:9,747,752...9,762,813
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase IEP RGD PMID:12819032 RGD:1580850 NCBI chr 3:153,547,807...153,595,643
Ensembl chr 3:153,580,861...153,595,642
JBrowse link
G Stat6 signal transducer and activator of transcription 6 severity ISO RGD PMID:12709397 RGD:7244143 NCBI chr 7:70,946,228...70,963,542
Ensembl chr 7:70,946,228...70,964,484
JBrowse link
G Tfpi tissue factor pathway inhibitor ISO RGD PMID:11796005 RGD:11062062 NCBI chr 3:71,852,738...71,902,127
Ensembl chr 3:71,852,744...71,893,618
JBrowse link
G Tlr2 toll-like receptor 2 treatment
severity
IDA
ISO
RGD PMID:23239000, PMID:11801667, PMID:20130923, PMID:22750071, PMID:23023072 RGD:7207892, RGD:7241087, RGD:7240552, RGD:7207896, RGD:7207894 NCBI chr 2:182,840,171...182,846,061
Ensembl chr 2:182,840,727...182,846,061
JBrowse link
G Tlr4 toll-like receptor 4 treatment IDA
ISO
RGD PMID:23239000, PMID:11801667, PMID:20130923 RGD:7207892, RGD:7241087, RGD:7240552 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052
JBrowse link
G Tnf tumor necrosis factor IEP protein:increased expression:serum RGD PMID:19925291 RGD:2315112 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A ISO mRNA:increased expression:lung RGD PMID:22728466 RGD:7245543 NCBI chr 4:157,864,905...157,877,634
Ensembl chr 4:157,864,969...157,877,633
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 IEP protein:increased expression:kidney RGD PMID:20164827 RGD:7240507 NCBI chr 2:219,071,193...219,090,931
Ensembl chr 2:219,071,193...219,097,619
JBrowse link
G Vwf von Willebrand factor IEP protein:increased expression:serum: RGD PMID:12684225 RGD:11080744 NCBI chr 4:158,085,059...158,219,525
Ensembl chr 4:158,088,505...158,219,523
JBrowse link
G Xdh xanthine dehydrogenase treatment IMP associated with Diabetes Mellitus, Type 2 RGD PMID:22995295, PMID:20616412 RGD:7247637, RGD:7247695 NCBI chr 6:25,149,570...25,211,273
Ensembl chr 6:25,149,235...25,211,494
JBrowse link
Liver Reperfusion Injury term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipoq adiponectin, C1Q and collagen domain containing treatment IDA RGD PMID:23762489 RGD:8695935 NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488
JBrowse link
G Adm adrenomedullin treatment IEP
ISO
mRNA,protein:increased expression:liver,plasma: RGD PMID:19212187, PMID:19212187 RGD:7364958, RGD:7364958 NCBI chr 1:175,443,189...175,447,260
Ensembl chr 1:175,445,088...175,447,259
JBrowse link
G Ager advanced glycosylation end product-specific receptor IEP mRNA:increased expression:liver RGD PMID:21431875 RGD:10402078 NCBI chr20:4,363,152...4,366,079
Ensembl chr20:4,363,152...4,366,079
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member treatment ISO
IEP
protein:altered expression:liver (mouse)
protein:altered expression:liver (rat)
RGD PMID:30671488, PMID:29589772 RGD:15036807, RGD:14975297 NCBI chr12:40,466,418...40,498,813
Ensembl chr12:40,466,495...40,498,752
JBrowse link
G Bad BCL2-associated agonist of cell death treatment IEP mRNA:increased expression:liver
associated with Non-alcoholic Fatty Liver Disease
RGD PMID:22647552, PMID:22847887 RGD:10053673, RGD:10053710 NCBI chr 1:222,198,516...222,207,459
Ensembl chr 1:222,198,534...222,207,453
JBrowse link
G Bax BCL2 associated X, apoptosis regulator treatment IEP mRNA:increased expression:liver
associated with Non-alcoholic Fatty Liver Disease
RGD PMID:22647552, PMID:21092002, PMID:22847887 RGD:10053673, RGD:5134995, RGD:10053710 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator treatment IDA
IEP
associated with Non-alcoholic Fatty Liver Disease RGD PMID:22847887, PMID:21092002 RGD:10053710, RGD:5134995 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcl2l1 Bcl2-like 1 treatment IEP associated with Non-alcoholic Fatty Liver Disease RGD PMID:22847887 RGD:10053710 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G C3 complement C3 treatment IEP RGD PMID:19854450 RGD:11040888 NCBI chr 9:9,721,137...9,747,084
Ensembl chr 9:9,721,105...9,747,167
JBrowse link
G Casp12 caspase 12 treatment IEP RGD PMID:29428101 RGD:13782166 NCBI chr 8:2,658,892...2,686,160
Ensembl chr 8:2,659,865...2,686,160
JBrowse link
G Casp8 caspase 8 treatment IEP
ISO
RGD PMID:23423194, PMID:15300206 RGD:8661760, RGD:14695087 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 treatment IEP RGD PMID:23364428 RGD:13782358 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 treatment
severity
IEP
ISO
mRNA, protein:increased expression:liver, serum (rat) RGD PMID:9500701, PMID:10630515, PMID:27229110 RGD:8549627, RGD:14995929, RGD:14995460 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 treatment
severity
ISO RGD PMID:28623253, PMID:28623253 RGD:14995305, RGD:14995305 NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315
JBrowse link
G Ccr2 C-C motif chemokine receptor 2 severity ISO RGD PMID:27229110 RGD:14995460
G Cd14 CD14 molecule IDA RGD PMID:22564590 RGD:7183676 NCBI chr18:29,560,341...29,562,290
Ensembl chr18:29,560,365...29,562,153
JBrowse link
G Cd40 CD40 molecule treatment IMP RGD PMID:14741776 RGD:8547795 NCBI chr 3:161,519,789...161,534,943
Ensembl chr 3:161,519,743...161,534,704
JBrowse link
G Cfh complement factor H treatment IEP
ISO
mRNA,protein:decreased expression:liver,plasma: RGD PMID:19212187, PMID:19212187 RGD:7364958, RGD:7364958 NCBI chr13:56,979,155...57,080,540
Ensembl chr13:56,978,607...57,080,622
JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 treatment IDA RGD PMID:21092002 RGD:5134995 NCBI chr14:18,743,678...18,745,457
Ensembl chr14:18,743,685...18,745,457
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 treatment ISO RGD PMID:18041715 RGD:27095942 NCBI chr14:17,210,733...17,212,930
Ensembl chr14:17,210,733...17,212,930
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 IEP mRNA:decreased expression:lung RGD PMID:19595018 RGD:2314952 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Elane elastase, neutrophil expressed IMP RGD PMID:10588515 RGD:10450560 NCBI chr 7:12,638,320...12,640,168
Ensembl chr 7:12,638,322...12,640,232
JBrowse link
G Epo erythropoietin treatment ISO RGD PMID:25769561 RGD:15090809 NCBI chr12:22,274,828...22,278,268
Ensembl chr12:22,274,828...22,278,266
JBrowse link
G Epor erythropoietin receptor IEP protein:increased phosphorylation:liver: RGD PMID:25769561 RGD:15090809 NCBI chr 8:22,969,737...22,974,468
Ensembl chr 8:22,969,745...22,974,321
JBrowse link
G F3 coagulation factor III, tissue factor treatment IMP RGD PMID:11750579 RGD:11341708 NCBI chr 2:225,310,686...225,322,281
Ensembl chr 2:225,310,624...225,322,272
JBrowse link
G Fadd Fas associated via death domain treatment IEP RGD PMID:23423194 RGD:8661760 NCBI chr 1:217,746,176...217,748,581
Ensembl chr 1:217,742,929...217,748,628
JBrowse link
G Fas Fas cell surface death receptor treatment IMP
IEP
protein:increased expression:liver RGD PMID:17235585, PMID:18561025, PMID:16222447 RGD:2290283, RGD:14700680, RGD:1600351 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Faslg Fas ligand treatment IMP RGD PMID:18561025 RGD:14700680 NCBI chr13:79,696,811...79,717,581
Ensembl chr13:79,698,445...79,705,705
JBrowse link
G Fga fibrinogen alpha chain IEP mRNA:increased expression:liver (rat) RGD PMID:23503399 RGD:9685021 NCBI chr 2:181,997,562...182,013,726
Ensembl chr 2:182,006,242...182,013,763
JBrowse link
G Fn1 fibronectin 1 IDA RGD PMID:12651615 RGD:7205470 NCBI chr 9:78,900,111...78,969,018
Ensembl chr 9:78,900,103...78,969,078
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta treatment IDA associated with nonalcoholic fatty liver disease RGD PMID:28807209 RGD:13792730 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
JBrowse link
G Gstm1 glutathione S-transferase mu 1 IEP mRNA:decreased expression:lung RGD PMID:19595018 RGD:2314952 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
JBrowse link
G H2ax H2A.X variant histone treatment IEP RGD PMID:23792534 RGD:8693718 NCBI chr 8:48,665,652...48,666,981
Ensembl chr 8:48,665,652...48,666,981
JBrowse link
G Hmgb1 high mobility group box 1 treatment IMP
IEP
protein:increased oxidation:liver
mRNA, protein:increased expression, altered localization:serum, hepatocyte, cytoplasm
RGD PMID:24578610, PMID:22514737, PMID:21431875 RGD:10402068, RGD:10402175, RGD:10402078 NCBI chr12:7,082,529...7,090,246
Ensembl chr16:37,500,017...37,502,237
JBrowse link
G Hmox1 heme oxygenase 1 treatment IEP RGD PMID:20446775 RGD:10755725 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hp haptoglobin treatment IEP RGD PMID:17187421, PMID:21699906 RGD:1626366, RGD:11041815 NCBI chr19:42,096,255...42,100,805
Ensembl chr19:42,097,995...42,100,804
JBrowse link
G Icam1 intercellular adhesion molecule 1 treatment IMP
IEP
associated with Intestinal Reperfusion Injury;protein:increased expression:liver RGD PMID:7884306, PMID:8780571 RGD:11520784, RGD:14402044 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 severity ISO RGD PMID:28938192 RGD:14985248 NCBI chr 1:141,874,354...141,893,674
Ensembl chr 1:141,866,283...141,893,705
JBrowse link
G Ikbkg inhibitor of nuclear factor kappa B kinase regulatory subunit gamma treatment IDA RGD PMID:22381173 RGD:12791280 NCBI chr  X:156,254,187...156,280,046
Ensembl chr  X:156,257,173...156,270,748
JBrowse link
G Il10 interleukin 10 treatment IDA RGD PMID:21911118 RGD:7364839 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il18 interleukin 18 treatment IEP
ISO
RGD PMID:25919765, PMID:14999688 RGD:14696667, RGD:14696668 NCBI chr 8:55,009,666...55,016,286
Ensembl chr 8:54,993,859...55,016,299
JBrowse link
G Il18bp interleukin 18 binding protein IEP mRNA,protein:increased expression:liver RGD PMID:25919765 RGD:14696667 NCBI chr 1:167,091,521...167,095,727
Ensembl chr 1:167,091,522...167,093,560
JBrowse link
G Il1a interleukin 1 alpha treatment IEP
IDA
mRNA:increased expression:lung
protein:increased expression:serum
RGD PMID:19595018, PMID:9840148, PMID:19283466 RGD:2314952, RGD:11059517, RGD:6907377 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il1b interleukin 1 beta IDA associated with Cholestasis RGD PMID:21468628 RGD:7175318 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il1rn interleukin 1 receptor antagonist treatment ISO
IMP
rat model treated with human protein RGD PMID:9000676, PMID:12451245 RGD:6909138, RGD:8551710 NCBI chr 3:1,449,778...1,468,624
Ensembl chr 3:1,452,644...1,468,614
JBrowse link
G Il6 interleukin 6 treatment IDA RGD PMID:24752458 RGD:11062134 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Jak2 Janus kinase 2 treatment IDA RGD PMID:22288937 RGD:10403073 NCBI chr 1:247,398,667...247,457,521
Ensembl chr 1:247,398,598...247,458,509
JBrowse link
G Lbp lipopolysaccharide binding protein IEP mRNA, protein:increased expression:liver RGD PMID:12134092 RGD:9685192 NCBI chr 3:154,786,232...154,812,910
Ensembl chr 3:154,786,215...154,813,464
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 IEP protein:increased activity:liver: RGD PMID:11679968 RGD:10412680 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Mfn2 mitofusin 2 treatment IEP mRNA, protein:decreased expression:liver (rat) RGD PMID:27363631, PMID:24898700 RGD:12910833, RGD:13204829 NCBI chr 5:164,684,244...164,715,414
Ensembl chr 5:164,684,509...164,714,145
JBrowse link
G Mir155 microRNA 155 ISO RGD PMID:28640790 RGD:21079442 NCBI chr11:24,176,603...24,176,667
Ensembl chr11:24,176,603...24,176,667
JBrowse link
G Mir223 microRNA 223 ISO RNA:increased expression:liver
RNA:increased expression:serum,liver
RGD PMID:19104939, PMID:28646120 RGD:13831297, RGD:21408574 NCBI chr  X:65,367,812...65,367,921
Ensembl chr  X:65,367,812...65,367,921
JBrowse link
G Mir34a microRNA 34a IEP miRNA:increased expression:liver RGD PMID:28963950 RGD:14695005 NCBI chr 5:167,092,491...167,092,592
Ensembl chr 5:167,092,491...167,092,592
JBrowse link
G Mmp15 matrix metallopeptidase 15 IEP mRNA:increased expression:lung RGD PMID:19595018 RGD:2314952 NCBI chr19:10,079,881...10,101,380
Ensembl chr19:10,079,765...10,101,451
JBrowse link
G Mmp9 matrix metallopeptidase 9 treatment IEP associated with Fatty Liver;mRNA, protein:decreased expression, decreased activity:liver RGD PMID:17255325 RGD:8547976 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Muc1 mucin 1, cell surface associated IEP mRNA, protein:decreased expression:bile duct RGD PMID:21775928 RGD:7364757 NCBI chr 2:188,543,137...188,547,874
Ensembl chr 2:188,543,137...188,547,874
JBrowse link
G Muc3 mucin 3, intestinal IEP mRNA, protein:decreased expression:bile duct RGD PMID:21775928 RGD:7364757 NCBI chr12:22,535,663...22,584,775 JBrowse link
G Muc4 mucin 4, cell surface associated IEP mRNA:decreased expression:bile duct RGD PMID:21775928 RGD:7364757 NCBI chr11:71,242,973...71,285,217
Ensembl chr11:71,243,334...71,284,939
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 treatment IEP RGD PMID:22288937, PMID:31952110 RGD:10403073, RGD:21201304 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nos3 nitric oxide synthase 3 treatment IEP RGD PMID:28966130 RGD:13450941 NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410
JBrowse link
G Proc protein C, inactivator of coagulation factors Va and VIIIa treatment ISO RGD PMID:12605111, PMID:18507760 RGD:11100021, RGD:11100046 NCBI chr18:24,918,402...24,928,822
Ensembl chr18:24,918,398...24,929,091
JBrowse link
G Serpinc1 serpin family C member 1 treatment IEP
ISO
RGD PMID:24726586, PMID:8589354 RGD:10450597, RGD:11038771 NCBI chr13:78,806,107...78,820,375
Ensembl chr13:78,805,347...78,833,192
JBrowse link
G Serpine1 serpin family E member 1 IEP protein:increased activity:plasma (rat) RGD PMID:12353078 RGD:8547901 NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482
JBrowse link
G Serping1 serpin family G member 1 treatment ISO RGD PMID:16367929 RGD:1580273 NCBI chr 3:72,161,230...72,171,109
Ensembl chr 3:72,161,189...72,171,078
JBrowse link
G Sirt1 sirtuin 1 treatment IEP RGD PMID:24557422 RGD:9497542 NCBI chr20:26,831,971...26,851,587
Ensembl chr20:26,833,357...26,852,199
JBrowse link
G Slpi secretory leukocyte peptidase inhibitor IEP RGD PMID:19595018 RGD:2314952 NCBI chr 3:160,799,979...160,802,228
Ensembl chr 3:160,799,981...160,802,433
JBrowse link
G Sod1 superoxide dismutase 1 treatment ISO human gene in a rat model RGD PMID:16555330, PMID:11779401 RGD:8655889, RGD:1581095 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
G Sod3 superoxide dismutase 3 treatment ISO human gene in a rat model RGD PMID:11779401 RGD:1581095 NCBI chr14:60,958,583...60,971,143
Ensembl chr14:60,958,592...60,964,324
JBrowse link
G Tert telomerase reverse transcriptase treatment ISO RGD PMID:19545665 RGD:11038676 NCBI chr 1:32,250,876...32,275,330
Ensembl chr 1:32,251,714...32,272,476
JBrowse link
G Tfpi tissue factor pathway inhibitor ISO RGD PMID:9921794 RGD:11062061 NCBI chr 3:71,852,738...71,902,127
Ensembl chr 3:71,852,744...71,893,618
JBrowse link
G Tlr2 toll-like receptor 2 treatment ISO
IEP
RGD PMID:16038046, PMID:25769561 RGD:15090805, RGD:15090809 NCBI chr 2:182,840,171...182,846,061
Ensembl chr 2:182,840,727...182,846,061
JBrowse link
G Tlr4 toll-like receptor 4 treatment
severity
IEP
ISO
mRNA:increased expression:liver
protein:increased expression:membrane raft:
RGD PMID:21431875, PMID:21693218, PMID:22797797, PMID:23395256, PMID:27064547 RGD:10402078, RGD:5685379, RGD:14697702, RGD:14697699, RGD:14697698 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052
JBrowse link
G Tnf tumor necrosis factor treatment IEP
IMP
protein:increased expression:serum (rat) RGD PMID:24726586, PMID:11592783, PMID:19357028, PMID:11129814, PMID:21125813, PMID:10454827, PMID:15457564, PMID:17164725 RGD:10450597, RGD:2325259, RGD:15039406, RGD:14995473, RGD:14995447, RGD:14985258, RGD:14985257, RGD:14696803 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A IEP protein:increased localization:mitochondrion RGD PMID:23423194 RGD:8661760 NCBI chr 4:157,864,905...157,877,634
Ensembl chr 4:157,864,969...157,877,633
JBrowse link
G Tradd TNFRSF1A-associated via death domain treatment IEP RGD PMID:23423194 RGD:8661760 NCBI chr19:37,214,461...37,221,099
Ensembl chr19:37,214,471...37,216,572
JBrowse link
G Ucp2 uncoupling protein 2 IEP mRNA:increased expression:liver RGD PMID:22195248 RGD:7175309 NCBI chr 1:165,506,375...165,512,744
Ensembl chr 1:165,506,361...165,512,744
JBrowse link
G Vegfa vascular endothelial growth factor A IEP RGD PMID:26451003 RGD:15036791 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
G Xdh xanthine dehydrogenase treatment IEP RGD PMID:24768926 RGD:13209011 NCBI chr 6:25,149,570...25,211,273
Ensembl chr 6:25,149,235...25,211,494
JBrowse link
Lung Reperfusion Injury term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator treatment IEP RGD PMID:23953793 RGD:10054119 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator treatment IEP RGD PMID:23953793 RGD:10054119 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Casp3 caspase 3 treatment IEP RGD PMID:23953793 RGD:10054119 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Egr1 early growth response 1 treatment IMP
IEP
RGD PMID:22878149, PMID:23232597 RGD:10395282, RGD:10395299 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429
JBrowse link
G Elane elastase, neutrophil expressed treatment IMP RGD PMID:17888675 RGD:10450582 NCBI chr 7:12,638,320...12,640,168
Ensembl chr 7:12,638,322...12,640,232
JBrowse link
G Hmgb1 high mobility group box 1 IEP protein:increased expression:lung RGD PMID:22115333 RGD:10402095 NCBI chr12:7,082,529...7,090,246
Ensembl chr16:37,500,017...37,502,237
JBrowse link
G Hmox1 heme oxygenase 1 IEP protein:increased expression:lung RGD PMID:21227458 RGD:10755577 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Icam1 intercellular adhesion molecule 1 treatment IEP RGD PMID:22503847 RGD:7240537 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Il1b interleukin 1 beta IDA
IEP
protein:increased expression:lung (rat) RGD PMID:23142117, PMID:23122581 RGD:7183185, RGD:7204125 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il4 interleukin 4 treatment IDA RGD PMID:24365768 RGD:10402797 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Mmp9 matrix metallopeptidase 9 IEP protein:increased activity:lung RGD PMID:18694576 RGD:5129703 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor treatment IEP RGD PMID:22503847 RGD:7240537 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G Nos3 nitric oxide synthase 3 IMP
ISO
mRNA:increased expression:lung (mouse) RGD PMID:20815765, PMID:25382268 RGD:4892012, RGD:11533932 NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 treatment IEP RGD PMID:21781312 RGD:6771212 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 IDA
IEP
protein:increased expression:alveolar macrophage (rat) RGD PMID:21781312, PMID:16449942 RGD:6771212, RGD:11541083 NCBI chr10:94,850,971...94,913,202 JBrowse link
G Proc protein C, inactivator of coagulation factors Va and VIIIa treatment ISO RGD PMID:19782612 RGD:11100035 NCBI chr18:24,918,402...24,928,822
Ensembl chr18:24,918,398...24,929,091
JBrowse link
G Serpine1 serpin family E member 1 treatment ISO
IDA
protein:increased expression:plasma (human) RGD PMID:17846288, PMID:11606484 RGD:8547720, RGD:11080966 NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482
JBrowse link
G Tlr4 toll-like receptor 4 treatment IEP RGD PMID:22115333 RGD:10402095 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052
JBrowse link
G Tnf tumor necrosis factor IMP RGD PMID:17294835 RGD:4143397 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
Myocardial Reperfusion Injury term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc8 ATP binding cassette subfamily C member 8 ISO RGD PMID:18316485 RGD:2301903 NCBI chr 1:102,110,708...102,191,287
Ensembl chr 1:102,110,708...102,191,287
JBrowse link
G Ada adenosine deaminase IDA protein:increased expression RGD PMID:16641873 RGD:1624305 NCBI chr 3:160,115,840...160,139,947
Ensembl chr 3:160,115,842...160,139,947
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing ISO CTD Direct Evidence: therapeutic CTD PMID:16155579 NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488
JBrowse link
G Adrb1 adrenoceptor beta 1 IMP
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:10900253, PMID:17201736 RGD:5129149 NCBI chr 1:277,537,585...277,538,985
Ensembl chr 1:277,537,585...277,538,985
JBrowse link
G Adrb2 adrenoceptor beta 2 IDA RGD PMID:16269402 RGD:1598746 NCBI chr18:57,513,792...57,515,834
Ensembl chr18:57,513,793...57,515,834
JBrowse link
G Ager advanced glycosylation end product-specific receptor IEP protein:increased expression:heart (rat) RGD PMID:16505177 RGD:1625342 NCBI chr20:4,363,152...4,366,079
Ensembl chr20:4,363,152...4,366,079
JBrowse link
G Agl amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase IMP RGD PMID:9281456 RGD:1598779 NCBI chr 2:219,788,234...219,843,189
Ensembl chr 2:219,788,234...219,842,986
JBrowse link
G Agt angiotensinogen ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:2535056, PMID:19166939 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433
JBrowse link
G Agtr1a angiotensin II receptor, type 1a IEP protein:increased expression:myocardium RGD PMID:21078800 RGD:5129194 NCBI chr17:35,907,102...35,958,136
Ensembl chr17:35,907,108...35,958,077
JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 IEP
ISO
protein:decreased expression:mitochondrion: RGD PMID:23685150, PMID:23685150 RGD:10053560, RGD:10053560 NCBI chr  X:135,304,063...135,343,062
Ensembl chr  X:135,304,066...135,343,087
JBrowse link
G Akt1 AKT serine/threonine kinase 1 IDA protein:increased phosphorylation:heart left ventricle RGD PMID:20217242 RGD:5509104 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Akt2 AKT serine/threonine kinase 2 IDA RGD PMID:16418318 RGD:2313347 NCBI chr 1:84,400,939...84,451,223
Ensembl chr 1:84,411,726...84,450,162
JBrowse link
G Alb albumin ISO CTD Direct Evidence: marker/mechanism CTD PMID:9572063 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member IDA RGD PMID:23468836 RGD:7241598 NCBI chr12:40,466,418...40,498,813
Ensembl chr12:40,466,495...40,498,752
JBrowse link
G Alox5 arachidonate 5-lipoxygenase IMP RGD PMID:20011686 RGD:2317527 NCBI chr 4:148,398,004...148,446,308
Ensembl chr 4:148,398,892...148,446,303
JBrowse link
G Angpt2 angiopoietin 2 IEP mRNA, protein:increased expression:myocardium (rat) RGD PMID:12737621 RGD:1601505 NCBI chr16:75,966,480...76,016,147
Ensembl chr16:75,966,352...76,016,195
JBrowse link
G Ank1 ankyrin 1 IDA RGD PMID:9378703 RGD:1599110 NCBI chr16:73,681,422...73,912,605
Ensembl chr16:73,681,422...73,827,488
JBrowse link
G Ank2 ankyrin 2 IDA RGD PMID:9378703 RGD:1599110 NCBI chr 2:231,224,643...231,522,655
Ensembl chr 2:231,226,949...231,648,122
JBrowse link
G Ankrd1 ankyrin repeat domain 1 IEP protein:decreased expression:myocardium RGD PMID:19299913 RGD:5133278 NCBI chr 1:254,726,985...254,745,673
Ensembl chr 1:254,726,969...254,735,548
JBrowse link
G Anxa1 annexin A1 treatment IEP
ISO
protein:increased expression:heart, leukocyte RGD PMID:11641252, PMID:22924634, PMID:22924634 RGD:2306910, RGD:7421655, RGD:7421655 NCBI chr 1:237,893,983...237,910,002
Ensembl chr 1:237,893,966...237,910,012
JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 IEP protein:altered localization:cytoplasm RGD PMID:17602955 RGD:2315672 NCBI chr15:27,849,943...27,852,083
Ensembl chr15:27,849,979...27,852,082
JBrowse link
G Arrb2 arrestin, beta 2 IEP RGD PMID:29016703 RGD:13506827 NCBI chr10:57,040,252...57,048,045
Ensembl chr10:57,040,267...57,048,134
JBrowse link
G Atf3 activating transcription factor 3 IEP RGD PMID:11485922 RGD:7327201 NCBI chr13:109,817,892...109,849,632
Ensembl chr13:109,817,728...109,849,632
JBrowse link
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 ISO CTD Direct Evidence: therapeutic CTD PMID:29702141 NCBI chr 2:204,003,742...204,032,023
Ensembl chr 2:204,003,742...204,032,023
JBrowse link
G Atp2a1 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 IMP RGD PMID:17630344 RGD:13782075 NCBI chr 1:197,855,912...197,875,038 JBrowse link
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 treatment ISO
IEP
CTD Direct Evidence: marker/mechanism CTD PMID:10734148, PMID:28637456 RGD:13782080 NCBI chr12:39,553,903...39,603,326
Ensembl chr12:39,553,903...39,603,326
JBrowse link
G Atp5f1d ATP synthase F1 subunit delta treatment IEP protein:decreased expression:myocardium (rat) RGD PMID:26109848, PMID:25305180 RGD:13792666, RGD:13792676 NCBI chr 7:12,426,807...12,432,120
Ensembl chr 7:12,426,809...12,432,130
JBrowse link
G Bad BCL2-associated agonist of cell death treatment IEP
IDA
protein:increased expression, decreased serine phosphorylation:heart RGD PMID:15339931, PMID:23364609 RGD:2292700, RGD:10053674 NCBI chr 1:222,198,516...222,207,459
Ensembl chr 1:222,198,534...222,207,453
JBrowse link
G Bax BCL2 associated X, apoptosis regulator treatment IEP
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:20026869, PMID:21223820, PMID:25547710 RGD:10054103, RGD:13782178 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator treatment IEP
IDA
RGD PMID:16289365, PMID:20821058, PMID:23364609 RGD:1599484, RGD:11561911, RGD:10053674 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcl2l1 Bcl2-like 1 treatment IDA RGD PMID:12668130 RGD:11035287 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G Becn1 beclin 1 treatment IDA
ISO
RGD PMID:20821058, PMID:20812860 RGD:11561911, RGD:11561944 NCBI chr10:89,209,944...89,225,297
Ensembl chr10:89,209,940...89,225,297
JBrowse link
G Bid BH3 interacting domain death agonist IDA
IEP
protein:increased cleavage:heart: RGD PMID:19940077, PMID:11934844 RGD:2317561, RGD:13782263 NCBI chr 4:153,439,812...153,465,247
Ensembl chr 4:153,442,218...153,465,203
JBrowse link
G Blk BLK proto-oncogene, Src family tyrosine kinase IEP mRNA:increased expression:left ventricle (rat) RGD PMID:17562528 RGD:1642307 NCBI chr15:46,555,552...46,593,778
Ensembl chr15:46,555,188...46,593,653
JBrowse link
G Bnip3 BCL2 interacting protein 3 treatment IMP RGD PMID:16645637 RGD:11561983 NCBI chr 1:211,248,098...211,265,282
Ensembl chr 1:211,248,098...211,265,282
JBrowse link
G Btg2 BTG anti-proliferation factor 2 IEP mRNA:increased expression:heart RGD PMID:12909328 RGD:2289075 NCBI chr13:50,913,185...50,916,944
Ensembl chr13:50,913,180...50,916,982
JBrowse link
G C3 complement C3 IEP protein:increased expression:myocardium RGD PMID:11560858 RGD:1582136 NCBI chr 9:9,721,137...9,747,084
Ensembl chr 9:9,721,105...9,747,167
JBrowse link
G C5 complement C5 treatment IDA
IMP
RGD PMID:9631876, PMID:23067403 RGD:1600666, RGD:7411626 NCBI chr 3:14,049,993...14,113,931
NCBI chr 3:14,206,466...14,229,141
Ensembl chr 3:14,049,995...14,229,080
JBrowse link
G Casp1 caspase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:14998631 NCBI chr 8:2,605,743...2,614,637
Ensembl chr 8:2,604,962...2,614,631
JBrowse link
G Casp12 caspase 12 treatment IEP
ISO
protein:increased activity:myocardium
CTD Direct Evidence: marker/mechanism
CTD PMID:14998631, PMID:19406177, PMID:25547710 RGD:2311458, RGD:13782178 NCBI chr 8:2,658,892...2,686,160
Ensembl chr 8:2,659,865...2,686,160
JBrowse link
G Casp3 caspase 3 treatment IMP
IEP
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:14998631, PMID:18470603, PMID:29538428 RGD:2293314, RGD:13782276 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp7 caspase 7 treatment ISO
IEP
CTD Direct Evidence: marker/mechanism CTD PMID:14998631, PMID:29538428 RGD:13782276 NCBI chr 1:277,190,557...277,242,779
Ensembl chr 1:277,190,964...277,242,774
JBrowse link
G Casp8 caspase 8 ISO
IEP
CTD Direct Evidence: marker/mechanism
protein:increased activity:cardiomyocyte
CTD PMID:14998631, PMID:11934844 RGD:13782263 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 treatment ISO
IEP
CTD Direct Evidence: marker/mechanism
protein:increased activity:cardiomyocyte,endothelial cell
CTD PMID:14998631, PMID:29538428, PMID:11934844 RGD:13782276, RGD:13782263 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Casr calcium-sensing receptor IEP protein:increased expression:ventricular myocardium (rat) RGD PMID:21766206 RGD:7205698 NCBI chr11:67,188,204...67,262,261
Ensembl chr11:67,188,630...67,258,771
JBrowse link
G Cast calpastatin IEP RGD PMID:12482022 RGD:5683872 NCBI chr 2:1,452,111...1,561,669
Ensembl chr 2:1,452,116...1,561,464
JBrowse link
G Cat catalase IEP
ISO
CTD Direct Evidence: therapeutic CTD PMID:21600015, PMID:11510883 RGD:1581149 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cbl Cbl proto-oncogene severity ISO RGD PMID:24583314 RGD:11251947 NCBI chr 8:48,481,256...48,564,775
Ensembl chr 8:48,489,036...48,564,722
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 IEP
ISO
mRNA:increased expression:heart (rat)
CTD Direct Evidence: marker/mechanism
CTD PMID:12087064, PMID:10908159 RGD:8549625 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccr2 C-C motif chemokine receptor 2 ISO protein:decreased expression:monocyte: RGD PMID:15786508 RGD:4892017
G Ccr5 C-C motif chemokine receptor 5 treatment ISO
IEP
protein:decreased expression:blood, monocyte (human) RGD PMID:15786508, PMID:23456481 RGD:4892017, RGD:8552227 NCBI chr 8:133,192,398...133,215,599
Ensembl chr 8:133,197,032...133,215,614
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator treatment IEP RGD PMID:18466417 RGD:11341714 NCBI chr 9:65,534,608...65,586,395
Ensembl chr 9:65,534,704...65,587,251
JBrowse link
G Cnr1 cannabinoid receptor 1 IMP RGD PMID:18771032 RGD:2316217 NCBI chr 5:49,307,584...49,333,064
Ensembl chr 5:49,311,030...49,333,056
JBrowse link
G Cnr2 cannabinoid receptor 2 IMP RGD PMID:17950273 RGD:2316224 NCBI chr 5:154,242,010...154,268,126
Ensembl chr 5:154,260,062...154,268,126
JBrowse link
G Crp C-reactive protein IEP protein:increased expression:serum RGD PMID:21122204 RGD:5128547 NCBI chr13:91,080,448...91,081,358
Ensembl chr13:91,054,974...91,093,713
JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 ISO protein:decreased expression:blood, monocyte RGD PMID:15786508 RGD:4892017 NCBI chr 8:128,740,756...128,754,514
Ensembl chr 8:128,740,756...128,754,514
JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 IMP RGD PMID:11342480 RGD:5135269 NCBI chr14:18,743,678...18,745,457
Ensembl chr14:18,743,685...18,745,457
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 IMP RGD PMID:11342480 RGD:5135269 NCBI chr14:18,731,346...18,733,391
Ensembl chr14:18,731,378...18,733,391
JBrowse link
G Cxcl6 C-X-C motif chemokine ligand 6 IMP RGD PMID:11342480 RGD:5135269 NCBI chr14:18,860,201...18,920,839
Ensembl chr14:18,860,264...18,862,407
JBrowse link
G Cybb cytochrome b-245 beta chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:19207477 NCBI chr  X:14,578,330...14,610,049
Ensembl chr  X:14,578,264...14,612,547
JBrowse link
G Diablo diablo, IAP-binding mitochondrial protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:14998631 NCBI chr12:38,490,230...38,503,344
Ensembl chr12:38,490,230...38,503,330
JBrowse link
G Ece1 endothelin converting enzyme 1 IMP
IEP
RGD PMID:18586023, PMID:12193087 RGD:4892580, RGD:7244160 NCBI chr 5:156,215,469...156,318,652
Ensembl chr 5:156,215,417...156,318,671
JBrowse link
G Edn1 endothelin 1 IEP
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:15642760, PMID:16700825, PMID:18586023 RGD:4892580 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Ednra endothelin receptor type A IMP RGD PMID:18586023 RGD:4892580 NCBI chr19:33,928,356...33,991,703
Ensembl chr19:33,928,356...33,991,703
JBrowse link
G Ednrb endothelin receptor type B IMP RGD PMID:21048781 RGD:4892332 NCBI chr15:88,004,775...88,036,354
Ensembl chr15:88,006,977...88,036,354
JBrowse link
G Egln1 egl-9 family hypoxia-inducible factor 1 susceptibility ISO RGD PMID:20185832 RGD:11251775 NCBI chr19:57,660,194...57,701,158
Ensembl chr19:57,662,278...57,699,113
JBrowse link
G Ephx2 epoxide hydrolase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19834332 NCBI chr15:42,757,241...42,794,211
Ensembl chr15:42,757,235...42,794,279
JBrowse link
G Esr1 estrogen receptor 1 IMP RGD PMID:18314151 RGD:4892299 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Esr2 estrogen receptor 2 ISO RGD PMID:18656630 RGD:5508820 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251
JBrowse link
G Fadd Fas associated via death domain treatment ISO
IEP
RGD PMID:26038570, PMID:26948086 RGD:11341801, RGD:13792504 NCBI chr 1:217,746,176...217,748,581
Ensembl chr 1:217,742,929...217,748,628
JBrowse link
G Fas Fas cell surface death receptor treatment IDA RGD PMID:21316771 RGD:8686424 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase treatment IEP RGD PMID:27129213 RGD:11574725 NCBI chr 4:157,676,336...157,680,322
Ensembl chr 4:157,676,595...157,679,962
JBrowse link
G Gcg glucagon treatment ISO RGD PMID:24125539 RGD:10402369 NCBI chr 3:48,442,635...48,451,650
Ensembl chr 3:48,442,635...48,451,650
JBrowse link
G Gja1 gap junction protein, alpha 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17445419 NCBI chr20:37,876,650...37,889,097
Ensembl chr20:37,876,650...37,889,089
JBrowse link
G Glrx glutaredoxin IEP mRNA:decreased expression:heart: RGD PMID:18163565 RGD:2306160 NCBI chr 2:2,606,032...2,615,944
Ensembl chr 2:2,605,996...2,615,944
JBrowse link
G Grk2 G protein-coupled receptor kinase 2 treatment
severity
susceptibility
IMP
ISO
IDA
associated with Diabetes Mellitus, Experimental
protein:increased expression:heart, mitochondrion (mouse)
associated with Hypertension
RGD PMID:27865836, PMID:23467820, PMID:24170934, PMID:27296507, PMID:27601479 RGD:13513990, RGD:13792779, RGD:13792704, RGD:13513995, RGD:13513993 NCBI chr 1:219,536,220...219,544,329
Ensembl chr 1:219,536,220...219,544,328
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta treatment IDA
IEP
RGD PMID:20217242, PMID:26918336, PMID:29978610 RGD:5509104, RGD:13792772, RGD:13792725 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
JBrowse link
G Gsr glutathione-disulfide reductase treatment IEP RGD PMID:24769323 RGD:10401892 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G H2ax H2A.X variant histone treatment IDA RGD PMID:23108649 RGD:8693739 NCBI chr 8:48,665,652...48,666,981
Ensembl chr 8:48,665,652...48,666,981
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha treatment IEP
ISO
IDA
mRNA:increased expression:heart
CTD Direct Evidence: marker/mechanism
protein:increased expression:myocardium
CTD PMID:18549825, PMID:22050707, PMID:12189448, PMID:20170615, PMID:19727523 RGD:1626327, RGD:9068872, RGD:5147885 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Hmgb1 high mobility group box 1 treatment IEP
ISO
IDA
CTD Direct Evidence: marker/mechanism CTD PMID:21113057, PMID:23531454, PMID:19540007 RGD:10402066, RGD:10402170 NCBI chr12:7,082,529...7,090,246
Ensembl chr16:37,500,017...37,502,237
JBrowse link
G Hmox1 heme oxygenase 1 treatment IDA
ISO
IEP
RGD PMID:12709584, PMID:23921302, PMID:22179023 RGD:1598392, RGD:10755585, RGD:10755573 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hrh2 histamine receptor H 2 susceptibility ISO RGD PMID:23467745 RGD:9685524 NCBI chr17:10,912,959...10,931,389
Ensembl chr17:10,921,507...10,952,441
JBrowse link
G Hrh3 histamine receptor H3 IDA RGD PMID:15076218 RGD:1626433 NCBI chr 3:175,474,310...175,479,395
Ensembl chr 3:175,473,078...175,479,395
JBrowse link
G Hsf1 heat shock transcription factor 1 ISO RGD PMID:22426029 RGD:10402789 NCBI chr 7:117,538,523...117,565,478
Ensembl chr 7:117,538,523...117,565,478
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 treatment IEP RGD PMID:24129401, PMID:25547710 RGD:11354962, RGD:13782178 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
JBrowse link
G Htra2 HtrA serine peptidase 2 ISO protein:increased expression:myocardium, cytosol (mouse) RGD PMID:15611365 RGD:5688376 NCBI chr 4:113,883,671...113,886,833
Ensembl chr 4:113,883,670...113,886,994
JBrowse link
G Icam1 intercellular adhesion molecule 1 IEP
ISO
protein:increased expression:heart (rat)
CTD Direct Evidence: marker/mechanism
CTD PMID:12087064, PMID:20851484 RGD:4145348 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Il10 interleukin 10 treatment IEP
IDA
protein:increased expression:plasma RGD PMID:19275881, PMID:23840272 RGD:2311056, RGD:7365001 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il17a interleukin 17A treatment IMP RGD PMID:22030025 RGD:9068944 NCBI chr 9:26,841,299...26,844,786
Ensembl chr 9:26,841,299...26,844,786
JBrowse link
G Il18 interleukin 18 ISO
IDA
RGD PMID:19164288, PMID:19805173 RGD:4889578, RGD:4889400 NCBI chr 8:55,009,666...55,016,286
Ensembl chr 8:54,993,859...55,016,299
JBrowse link
G Il18bp interleukin 18 binding protein ISO mRNA:increased expression:heart RGD PMID:19164288, PMID:19805173 RGD:4889578, RGD:4889400 NCBI chr 1:167,091,521...167,095,727
Ensembl chr 1:167,091,522...167,093,560
JBrowse link
G Il18rap interleukin 18 receptor accessory protein ISO RGD PMID:19164288 RGD:4889578 NCBI chr 9:47,225,543...47,255,805
Ensembl chr 9:47,225,585...47,258,503
JBrowse link
G Il1a interleukin 1 alpha treatment ISO
IEP
RGD PMID:8576926, PMID:7622355 RGD:7794741, RGD:7794764 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il1b interleukin 1 beta IEP mRNA:increased expression:heart RGD PMID:17134725 RGD:1626628 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il1rn interleukin 1 receptor antagonist ISO rat model treated with human protein RGD PMID:22649318 RGD:7174360 NCBI chr 3:1,449,778...1,468,624
Ensembl chr 3:1,452,644...1,468,614
JBrowse link
G Il6 interleukin 6 treatment IDA RGD PMID:27087891 RGD:11062149 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Il6r interleukin 6 receptor ISO RGD PMID:16056242 RGD:1625435 NCBI chr 2:189,196,180...189,255,987
Ensembl chr 2:189,205,701...189,254,628
JBrowse link
G Irak1 interleuk