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Term:Hearing Loss, Cisplatin-Induced
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Accession:DOID:9004673 term browser browse the term
Definition:Hearing loss due to the toxic effects of the anti-cancer drug cisplatin upon the auditory hair cells of the cochlea.
Synonyms:exact_synonym: CIHL;   cisplatin-induced ototoxicity
 related_synonym: Hearing Loss, Cisplatin-Induced, Susceptibility To
 primary_id: OMIM:613290
 alt_id: RDO:0009807;   RDO:9000044
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Hearing Loss, Cisplatin-Induced term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acyp2 acylphosphatase 2 JBrowse link 14 114,891,245 115,052,497 RGD:11554173
G Camk2a calcium/calmodulin-dependent protein kinase II alpha JBrowse link 18 56,193,978 56,295,869 RGD:9685025
G Camk2b calcium/calmodulin-dependent protein kinase II beta JBrowse link 14 86,208,876 86,297,727 RGD:9685025
G Cat catalase JBrowse link 3 93,379,872 93,412,058 RGD:9197256
G Comt catechol-O-methyltransferase JBrowse link 11 86,715,981 86,735,630 RGD:11554173
G Gsk3b glycogen synthase kinase 3 beta JBrowse link 11 65,060,884 65,208,842 RGD:10045579
G Tpmt thiopurine S-methyltransferase JBrowse link 17 18,029,090 18,047,716 RGD:11554173

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 15619
    sensory system disease 4674
      auditory system disease 684
        inner ear disease 495
          sensorineural hearing loss 459
            Hearing Loss, Cisplatin-Induced 7
Path 2
Term Annotations click to browse term
  disease 15619
    disease of anatomical entity 14948
      nervous system disease 10216
        sensory system disease 4674
          Otorhinolaryngologic Diseases 1075
            auditory system disease 684
              Hearing Disorders 569
                Hearing Loss 565
                  Deafness 249
                    nonsyndromic deafness 151
                      drug-induced hearing loss 7
                        Hearing Loss, Cisplatin-Induced 7
paths to the root


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.