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Term:Kidney Reperfusion Injury
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Accession:DOID:9006223 term browser browse the term
Definition:Adverse functional, metabolic, or structural changes in ischemic tissues resulting from the restoration of blood flow to the kidney, including swelling; hemorrhage; necrosis; and damage from free radicals.
Synonyms:exact_synonym: Kidney Ischemia-Reperfusion Injury;   Renal Ischemia-Reperfusion Injury;   Renal Reperfusion Injury
 primary_id: RDO:9000009
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Kidney Reperfusion Injury term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ace2 angiotensin I converting enzyme 2 JBrowse link NW_004955519 2,591,229 2,643,705 RGD:9068941
G Adam17 ADAM metallopeptidase domain 17 JBrowse link NW_004955487 5,180,241 5,218,298 RGD:9068941
G Adam2 ADAM metallopeptidase domain 2 JBrowse link NW_004955403 50,046,262 50,115,004 RGD:9068941
G Adamts1 ADAM metallopeptidase with thrombospondin type 1 motif 1 JBrowse link NW_004955407 26,524,487 26,533,038 RGD:9068941
G Adipoq adiponectin, C1Q and collagen domain containing JBrowse link NW_004955420 20,911,181 20,922,992 RGD:9068941
G Adm adrenomedullin JBrowse link NW_004955414 25,951,473 25,953,593 RGD:9068941
G Akr1a1 aldo-keto reductase family 1 member A1 JBrowse link NW_004955464 12,715,238 12,729,034 RGD:9068941
G Aldh2 aldehyde dehydrogenase 2 family member JBrowse link NW_004955482 8,352,569 8,383,097 RGD:9068941
G Anxa1 annexin A1 JBrowse link NW_004955512 5,686,508 5,703,645 RGD:9068941
G Anxa5 annexin A5 JBrowse link NW_004955428 18,873,782 18,907,955 RGD:9068941
G Apaf1 apoptotic peptidase activating factor 1 JBrowse link NW_004955405 34,619,780 34,693,616 RGD:9068941
G Apoa1 apolipoprotein A1 JBrowse link NW_004955412 18,170,331 18,172,298 RGD:9068941
G Atm ATM serine/threonine kinase JBrowse link NW_004955412 10,422,753 10,531,406 RGD:9068941
G Bax BCL2 associated X, apoptosis regulator JBrowse link NW_004955559 1,695,960 1,700,246 RGD:9068941
G Bcl2 BCL2 apoptosis regulator JBrowse link NW_004955402 46,911,125 47,084,214 RGD:9068941
G Bdkrb1 bradykinin receptor B1 JBrowse link NW_004955438 16,500,219 16,505,394 RGD:9068941
G Becn1 beclin 1 JBrowse link NW_004955451 16,616,595 16,625,731 RGD:9068941
G Bnip3 BCL2 interacting protein 3 JBrowse link NW_004955477 9,621,812 9,630,406 RGD:9068941
G C3 complement C3 JBrowse link NW_004955495 2,796,601 2,824,233 RGD:9068941
G Casp3 caspase 3 JBrowse link NW_004955403 24,315,712 24,326,271 RGD:9068941
G Casp7 caspase 7 JBrowse link NW_004955431 18,685,408 18,723,221 RGD:9068941
G Cd14 CD14 molecule JBrowse link NW_004955418 73,736 75,345 RGD:9068941
G Cd40 CD40 molecule JBrowse link NW_004955445 11,191,817 11,202,156 RGD:9068941
G Cfb complement factor B JBrowse link NW_004955437 461,235 466,908 RGD:9068941
G Ciita class II major histocompatibility complex transactivator JBrowse link NW_004955442 7,600,903 7,647,619 RGD:9068941
G Csf1 colony stimulating factor 1 JBrowse link NW_004955435 13,404,236 13,423,059 RGD:9068941
G Csf1r colony stimulating factor 1 receptor JBrowse link NW_004955415 4,434,486 4,462,505 RGD:9068941
G Ctla4 cytotoxic T-lymphocyte associated protein 4 JBrowse link NW_004955457 11,028,707 11,034,898 RGD:9068941
G Cxcr4 C-X-C motif chemokine receptor 4 JBrowse link NW_004955440 3,456,165 3,460,024 RGD:9068941
G Daxx death domain associated protein JBrowse link NW_004955437 1,869,692 1,874,041 RGD:9068941
G Dhfr dihydrofolate reductase JBrowse link NW_004955418 29,274,170 29,283,028 RGD:9068941
G Drd3 dopamine receptor D3 JBrowse link NW_004955427 14,219,519 14,252,178 RGD:9068941
G Egln1 egl-9 family hypoxia inducible factor 1 JBrowse link NW_004955492 7,407,800 7,454,851 RGD:9068941
G Egln3 egl-9 family hypoxia inducible factor 3 JBrowse link NW_004955409 26,939,933 26,967,156 RGD:9068941
G Eng endoglin JBrowse link NW_004955419 818,797 853,319 RGD:9068941
G Ep300 E1A binding protein p300 JBrowse link NW_004955413 26,647,553 26,727,875 RGD:9068941
G Epo erythropoietin JBrowse link NW_004955573 203,875 206,078 RGD:9068941
G F3 coagulation factor III, tissue factor JBrowse link NW_004955423 254,060 264,448 RGD:9068941
G Fas Fas cell surface death receptor JBrowse link NW_004955425 3,961,671 3,987,513 RGD:9068941
G Faslg Fas ligand JBrowse link NW_004955406 13,098,479 13,107,045 RGD:9068941
G Fga fibrinogen alpha chain JBrowse link NW_004955471 8,806,964 8,814,671 RGD:9068941
G Fgb fibrinogen beta chain JBrowse link NW_004955471 8,824,901 8,832,836 RGD:9068941
G Fgg fibrinogen gamma chain JBrowse link NW_004955471 8,786,910 8,794,947 RGD:9068941
G Fn1 fibronectin 1 JBrowse link NW_004955457 629,599 694,948 RGD:9068941
G Fos Fos proto-oncogene, AP-1 transcription factor subunit JBrowse link NW_004955523 307,181 310,728 RGD:9068941
G Gfer growth factor, augmenter of liver regeneration JBrowse link NW_004955442 15,280,753 15,283,405 RGD:9068941
G Glo1 glyoxalase I JBrowse link NW_004955437 4,728,709 4,749,834 RGD:9068941
G Gsr glutathione-disulfide reductase JBrowse link NW_004955463 7,130,459 7,153,631 RGD:9068941
G Has1 hyaluronan synthase 1 JBrowse link NW_004955558 826,853 836,809 RGD:9068941
G Has2 hyaluronan synthase 2 JBrowse link NW_004955540 593,316 609,760 RGD:9068941
G Havcr1 hepatitis A virus cellular receptor 1 JBrowse link NW_004955408 11,047,679 11,070,492 RGD:9068941
G Hif1a hypoxia inducible factor 1 subunit alpha JBrowse link NW_004955466 8,000,311 8,022,497 RGD:9068941
G Hmox1 heme oxygenase 1 JBrowse link NW_004955405 43,124,447 43,128,873 RGD:9068941
G Hsf1 heat shock transcription factor 1 JBrowse link NW_004955454 2,907,265 2,932,352 RGD:9068941
G Hspa8 heat shock protein family A (Hsp70) member 8 JBrowse link NW_004955412 23,863,513 23,867,984 RGD:9068941
G Hyal1 hyaluronidase 1 JBrowse link NW_004955532 2,113,016 2,116,093 RGD:9068941
G Hyal2 hyaluronidase 2 JBrowse link NW_004955532 2,120,781 2,125,083 RGD:9068941
G Ifng interferon gamma JBrowse link NW_004955458 14,643,333 14,648,020 RGD:9068941
G Igf1r insulin like growth factor 1 receptor JBrowse link NW_004955416 26,101,090 26,382,660 RGD:9068941
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta JBrowse link NW_004955536 611,965 658,647 RGD:9068941
G Il10 interleukin 10 JBrowse link NW_004955406 42,307,789 42,312,255 RGD:9068941
G Il18 interleukin 18 JBrowse link NW_004955412 13,807,361 13,826,007 RGD:9068941
G Il1b interleukin 1 beta JBrowse link NW_004955470 1,486,936 1,491,888 RGD:9068941
G Il1rn interleukin 1 receptor antagonist JBrowse link NW_004955470 1,145,022 1,159,413 RGD:9068941
G Itgb2 integrin subunit beta 2 JBrowse link NW_004955407 41,779,849 41,805,637 RGD:9068941
G Kcnj11 potassium inwardly rectifying channel subfamily J member 11 JBrowse link NW_004955414 32,209,426 32,212,424 RGD:9068941
G Kl klotho JBrowse link NW_004955431 12,782,913 12,833,215 RGD:9068941
G Lep leptin JBrowse link NW_004955479 9,266,604 9,276,568 RGD:9068941
G Lgals3 galectin 3 JBrowse link NW_004955409 8,448,120 8,452,437 RGD:9068941
G LOC102021597 alpha-1-antiproteinase S-like JBrowse link NW_004955438 17,920,200 17,929,105 RGD:9068941
G LOC102023780 aromatase JBrowse link NW_004955409 3,198,622 3,313,072 RGD:9068941
G LOC102025775 histone H2AX JBrowse link NW_004955412 20,203,173 20,204,714 RGD:9068941
G Map1lc3a microtubule associated protein 1 light chain 3 alpha JBrowse link NW_004955422 26,774,466 26,776,024 RGD:9068941
G Map3k5 mitogen-activated protein kinase kinase kinase 5 JBrowse link NW_004955439 162,499 376,919 RGD:9068941
G Mpo myeloperoxidase JBrowse link NW_004955451 4,743,744 4,753,358 RGD:9068941
G Muc1 mucin 1, cell surface associated JBrowse link NW_004955545 1,657,728 1,662,112 RGD:9068941
G Myc MYC proto-oncogene, bHLH transcription factor JBrowse link NW_004955461 2,714,022 2,718,872 RGD:9068941
G Ndufb8 NADH:ubiquinone oxidoreductase subunit B8 JBrowse link NW_004955485 9,607,781 9,613,123 RGD:9068941
G Nes nestin JBrowse link NW_004955545 2,748,132 2,756,595 RGD:9068941
G Nos3 nitric oxide synthase 3 JBrowse link NW_004955491 5,438,228 5,457,308 RGD:9068941
G Nppa natriuretic peptide A JBrowse link NW_004955486 2,061,196 2,062,805 RGD:9068941
G Nqo1 NAD(P)H quinone dehydrogenase 1 JBrowse link NW_004955484 7,012,373 7,028,182 RGD:9068941
G Nr4a1 nuclear receptor subfamily 4 group A member 1 JBrowse link NW_004955547 2,404,532 2,426,882 RGD:9068941
G Ogg1 8-oxoguanine DNA glycosylase JBrowse link NW_004955561 1,277,362 1,282,949 RGD:9068941
G Pax2 paired box 2 JBrowse link NW_004955485 9,351,913 9,430,607 RGD:9068941
G Pdgfb platelet derived growth factor subunit B JBrowse link NW_004955413 25,150,702 25,166,987 RGD:9068941
G Pdgfra platelet derived growth factor receptor alpha JBrowse link NW_004955447 16,570,652 16,613,410 RGD:9068941
G Pdgfrb platelet derived growth factor receptor beta JBrowse link NW_004955415 4,365,848 4,403,317 RGD:9068941
G Pkd2 polycystin 2, transient receptor potential cation channel JBrowse link NW_004955474 1,831,221 1,868,170 RGD:9068941
G Ppargc1a PPARG coactivator 1 alpha JBrowse link NW_004955480 543,397 1,188,376 RGD:9068941
G Rnls renalase, FAD dependent amine oxidase JBrowse link NW_004955425 4,368,620 4,667,947 RGD:9068941
G Serpinc1 serpin family C member 1 JBrowse link NW_004955406 14,024,183 14,036,206 RGD:9068941
G Shh sonic hedgehog signaling molecule JBrowse link NW_004955491 8,647,133 8,657,381 RGD:9068941
G Sirt1 sirtuin 1 JBrowse link NW_004955425 20,280,725 20,307,663 RGD:9068941
G Slc22a2 solute carrier family 22 member 2 JBrowse link NW_004955439 20,567,241 20,608,281 RGD:9068941
G Slc34a1 solute carrier family 34 member 1 JBrowse link NW_004955408 29,626,775 29,640,811 RGD:9068941
G Src SRC proto-oncogene, non-receptor tyrosine kinase JBrowse link NW_004955445 19,213,210 19,227,670 RGD:9068941
G Stat6 signal transducer and activator of transcription 6 JBrowse link NW_004955458 4,833,417 4,847,956 RGD:9068941
G Tfpi tissue factor pathway inhibitor JBrowse link NW_004955403 10,925,155 11,004,229 RGD:9068941
G Tlr2 toll like receptor 2 JBrowse link NW_004955471 8,011,710 8,019,063 RGD:9068941
G Tlr4 toll like receptor 4 JBrowse link NW_004955419 10,190,937 10,201,896 RGD:9068941
G Tnf tumor necrosis factor JBrowse link NW_004955437 117,267 119,899 RGD:9068941
G Tnfrsf1a TNF receptor superfamily member 1A JBrowse link NW_004955413 3,982,670 3,996,320 RGD:9068941
G Vcam1 vascular cell adhesion molecule 1 JBrowse link NW_004955435 5,390,745 5,410,025 RGD:9068941
G Vwf von Willebrand factor JBrowse link NW_004955413 3,672,470 3,825,588 RGD:9068941
Chronic Allograft Nephropathy term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aco1 aconitase 1 JBrowse link NW_004955472 3,141,473 3,170,959 RGD:9068941
G Alb albumin JBrowse link NW_004955447 9,327 21,212 RGD:9068941
G Clu clusterin JBrowse link NW_004955403 50,160,598 50,175,876 RGD:9068941
G Mmp7 matrix metallopeptidase 7 JBrowse link NW_004955412 5,780,772 5,792,485 RGD:9068941
G Pdgfa platelet derived growth factor subunit A JBrowse link NW_004955460 8,328,400 8,346,755 RGD:9068941
G Pdgfb platelet derived growth factor subunit B JBrowse link NW_004955413 25,150,702 25,166,987 RGD:9068941
G Pdgfra platelet derived growth factor receptor alpha JBrowse link NW_004955447 16,570,652 16,613,410 RGD:9068941
G Pdgfrb platelet derived growth factor receptor beta JBrowse link NW_004955415 4,365,848 4,403,317 RGD:9068941
G Plau plasminogen activator, urokinase JBrowse link NW_004955437 17,995,726 18,000,542 RGD:9068941
G Pparg peroxisome proliferator activated receptor gamma JBrowse link NW_004955429 14,814,690 14,936,869 RGD:9068941
G Serpine1 serpin family E member 1 JBrowse link NW_004955456 16,147,523 16,157,040 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 11744
    disease of anatomical entity 11304
      cardiovascular system disease 3043
        vascular disease 2185
          Reperfusion Injury 589
            Kidney Reperfusion Injury 113
              Chronic Allograft Nephropathy 11
Path 2
Term Annotations click to browse term
  disease 11744
    disease of anatomical entity 11304
      Urogenital Diseases 3337
        urinary system disease 1491
          kidney disease 1305
            kidney failure 389
              acute kidney failure 226
                Kidney Reperfusion Injury 113
                  Chronic Allograft Nephropathy 11
paths to the root


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.