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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Eye Injuries
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Accession:DOID:9006447 term browser browse the term
Definition:Damage or trauma inflicted to the eye by external means. The concept includes both surface injuries and intraocular injuries.
Synonyms:exact_synonym: Eye Injury
 primary_id: MESH:D005131;   RDO:0005555
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants           Sort by:
 
Eye Injuries term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgf2 fibroblast growth factor 2 ISO
IEP
protein:increased expression:lens RGD PMID:15273655, PMID:15273655 RGD:8655664, RGD:8655664 NCBI chr 2:124,081,072...124,134,133
Ensembl chr 2:124,081,072...124,134,681
JBrowse link
G Mir183 microRNA 183 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27208084 NCBI chr 4:57,463,569...57,463,678
Ensembl chr 4:57,463,569...57,463,678
JBrowse link
G Mir96 microRNA 96 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27208084 NCBI chr 4:57,463,366...57,463,471
Ensembl chr 4:57,463,366...57,463,471
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma treatment ISO RGD PMID:18658087 RGD:8552893 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
Corneal Injuries term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh3a1 aldehyde dehydrogenase 3 family, member A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28038895 NCBI chr10:47,490,168...47,499,855
Ensembl chr10:47,490,153...47,499,876
JBrowse link
G Tp63 tumor protein p63 ISO RGD PMID:12167247 RGD:11568649 NCBI chr11:78,234,853...78,456,559
Ensembl chr11:78,234,800...78,456,501
JBrowse link
Corneal Perforation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ifng interferon gamma ISO mRNA,protein:increased expression:corneal RGD PMID:15832292 RGD:8157597 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
Eye Burns term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il10 interleukin 10 treatment IDA RGD PMID:22553604 RGD:7364851 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il1b interleukin 1 beta ISO protein:increased expression:retina RGD PMID:9618720 RGD:7794723 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma IEP protein:increased expression:cornea, neutrophil, macrophage (rat) RGD PMID:24194635 RGD:8552904 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
Eye Injuries, Penetrating term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgf2 fibroblast growth factor 2 ISO mRNA:increased expression:retina RGD PMID:9268592 RGD:8655567 NCBI chr 2:124,081,072...124,134,133
Ensembl chr 2:124,081,072...124,134,681
JBrowse link
G Neo1 neogenin 1 IEP protein:increased expression:retina RGD PMID:21887516 RGD:9850142 NCBI chr 8:63,649,871...63,756,394
Ensembl chr 8:63,653,266...63,750,531
JBrowse link
G Rgma repulsive guidance molecule BMP co-receptor a IEP protein:increased expression:retina RGD PMID:21887516 RGD:9850142 NCBI chr 1:134,699,053...134,742,512
Ensembl chr 1:134,699,299...134,742,514
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 16108
    sensory system disease 5162
      eye disease 2593
        Eye Injuries 11
          Anterior Capsular Rupture, Ocular 0
          Corneal Injuries + 3
          Eye Burns 3
          Eye Foreign Bodies 0
          Eye Injuries, Penetrating 3
          Posterior Capsular Rupture, Ocular 0
Path 2
Term Annotations click to browse term
  disease 16108
    disease of anatomical entity 15356
      nervous system disease 10865
        Nervous System Trauma 530
          Craniocerebral Trauma 336
            Facial Injuries 13
              Eye Injuries 11
                Anterior Capsular Rupture, Ocular 0
                Corneal Injuries + 3
                Eye Burns 3
                Eye Foreign Bodies 0
                Eye Injuries, Penetrating 3
                Posterior Capsular Rupture, Ocular 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.