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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Anhedonia
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Accession:DOID:9006604 term browser browse the term
Definition:Inability to experience pleasure due to impairment or dysfunction of normal psychological and neurobiological mechanisms. It is a symptom of many PSYCHOTIC DISORDERS (e.g., DEPRESSIVE DISORDER, MAJOR; and SCHIZOPHRENIA).
Synonyms:exact_synonym: Anhedonias;   Physical Anhedonia;   Physical Anhedonias;   Social Anhedonia;   Social Anhedonias
 primary_id: MESH:D059445;   RDO:0010019
For additional species annotation, visit the Alliance of Genome Resources.


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Anhedonia term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Penk proenkephalin IEP RGD PMID:24090157 RGD:10003087 NCBI chr 5:17,056,412...17,061,762
Ensembl chr 5:17,056,419...17,061,837
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Term paths to the root
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Term Annotations click to browse term
  disease 16023
    Pathological Conditions, Signs and Symptoms 8754
      Signs and Symptoms 5266
        Neurologic Manifestations 4214
          Neurobehavioral Manifestations 2411
            Anhedonia 1
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.