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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Murine Acquired Immunodeficiency Syndrome
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Accession:DOID:9006623 term browser browse the term
Definition:Acquired defect of cellular immunity that occurs in mice infected with mouse leukemia viruses (MuLV). The syndrome shows striking similarities with human AIDS and is characterized by lymphadenopathy, profound immunosuppression, enhanced susceptibility to opportunistic infections, and B-cell lymphomas.
Synonyms:exact_synonym: MAIDS;   Murine AIDS;   Murine AIDSs;   Murine Acquired Immune Deficiency Syndrome;   Murine Acquired Immuno Deficiency Syndrome
 primary_id: MESH:D016183;   RDO:0006946
For additional species annotation, visit the Alliance of Genome Resources.


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Murine Acquired Immunodeficiency Syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd40 CD40 molecule susceptibility ISO RGD PMID:12438641 RGD:11520795 NCBI chr 3:161,519,789...161,534,943
Ensembl chr 3:161,519,743...161,534,704
JBrowse link
G Cd40lg CD40 ligand treatment ISO RGD PMID:8642687 RGD:11520796 NCBI chr  X:159,703,703...159,714,886
Ensembl chr  X:159,703,578...159,716,562
JBrowse link
G Il10 interleukin 10 ISO RGD PMID:23415673 RGD:7364815 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 16058
    syndrome 6996
      Murine Acquired Immunodeficiency Syndrome 3
Path 2
Term Annotations click to browse term
  disease 16058
    disease by infectious agent 1759
      viral infectious disease 1457
        RNA Virus Infections 1290
          Retroviridae Infections 185
            Murine Acquired Immunodeficiency Syndrome 3
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.