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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Urinary Tract Infections
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Accession:DOID:9006979 term browser browse the term
Definition:Inflammatory responses of the epithelium of the URINARY TRACT to microbial invasions. They are often bacterial infections with associated BACTERIURIA and PYURIA.
Synonyms:exact_synonym: Urinary Tract Infection
 primary_id: MESH:D014552
For additional species annotation, visit the Alliance of Genome Resources.


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Urinary Tract Infections term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cxcr1 C-X-C motif chemokine receptor 1 ISO RGD PMID:21151974 RGD:7207862 NCBI chr 9:81,466,430...81,469,299
Ensembl chr 9:81,466,332...81,469,274
JBrowse link
G Cxcr2 C-X-C motif chemokine receptor 2 ISO RGD PMID:18401338 RGD:7257688 NCBI chr 9:81,427,275...81,435,065
Ensembl chr 9:81,427,730...81,434,102
JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B ISO DNA: SNP: :g.1267A>G RGD PMID:20379347 RGD:7242733 NCBI chr20:4,877,638...4,880,112
Ensembl chr20:2,699,712...2,701,815
JBrowse link
G Il18 interleukin 18 IEP protein:increased expression:urine RGD PMID:19171043 RGD:2311084 NCBI chr 8:55,009,666...55,016,286
Ensembl chr 8:54,993,859...55,016,299
JBrowse link
G Il1a interleukin 1 alpha IEP
ISO
protein:increased expression:urine RGD PMID:19171043, PMID:21690238 RGD:2311084, RGD:6907113 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il1b interleukin 1 beta IEP
ISO
protein:increased expression:urine RGD PMID:19171043, PMID:20886104 RGD:2311084, RGD:7175340 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Nos2 nitric oxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:9011564 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Pomc proopiomelanocortin ISO CTD Direct Evidence: marker/mechanism CTD PMID:6254450 NCBI chr 6:28,382,937...28,388,771
Ensembl chr 6:28,382,962...28,388,967
JBrowse link
G Tlr2 toll-like receptor 2 susceptibility ISO DNA:polymorphism: :p.R753Q (human) RGD PMID:18001294 RGD:7240561 NCBI chr 2:182,840,171...182,846,061
Ensembl chr 2:182,840,727...182,846,061
JBrowse link
G Tlr4 toll-like receptor 4 susceptibility ISO DNA:snp:cds:p.D299G (human) RGD PMID:19543401 RGD:7246906 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052
JBrowse link
urinary schistosomiasis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 susceptibility ISO DNA:SNPs:multiple:Gabonese(human) RGD PMID:22288822 RGD:7204674 NCBI chr 9:67,699,397...67,706,068
Ensembl chr 9:67,699,379...67,706,065
JBrowse link
G Il5 interleukin 5 resistance ISO RGD PMID:9697734 RGD:7241010 NCBI chr10:39,066,716...39,069,587
Ensembl chr10:39,066,716...39,069,587
JBrowse link
G Stat6 signal transducer and activator of transcription 6 severity ISO DNA:SNP:enhancer: (rs324013) RGD PMID:18273035 RGD:7243977 NCBI chr 7:70,946,228...70,963,542
Ensembl chr 7:70,946,228...70,964,484
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 16096
    disease of anatomical entity 15346
      Urogenital Diseases 4143
        urinary system disease 2066
          Urinary Tract Infections 13
            acute gonococcal cystitis 0
            bacteriuria 0
            pyuria 0
            sparganosis 0
            urinary schistosomiasis 3
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.