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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Dysbiosis
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Accession:DOID:9007204 term browser browse the term
Definition:Changes in quantitative and qualitative composition of MICROBIOTA. The changes may lead to altered host microbial interaction or homeostatic imbalance that can contribute to a disease state often with inflammation.
Synonyms:exact_synonym: Disbacterioses;   Disbacteriosis;   Disbioses;   Disbiosis;   Dys symbiosis;   Dys-symbioses;   Dysbacterioses;   Dysbacteriosis;   Dysbioses
 primary_id: MESH:D064806;   RDO:0015842
For additional species annotation, visit the Alliance of Genome Resources.


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Dysbiosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alpi alkaline phosphatase, intestinal IMP RGD PMID:28985873 RGD:14367878 NCBI chr 9:94,197,616...94,201,910
Ensembl chr 9:94,197,618...94,201,084
JBrowse link
G Foxp3 forkhead box P3 treatment IEP RGD PMID:32227764 RGD:38549571 NCBI chr  X:15,753,175...15,768,648
Ensembl chr  X:15,753,175...15,768,522
JBrowse link
G Il10 interleukin 10 treatment IEP RGD PMID:32227764 RGD:38549571 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il21 interleukin 21 treatment IEP RGD PMID:32227764 RGD:38549571 NCBI chr 2:123,965,021...123,972,356
Ensembl chr 2:123,965,021...123,972,356
JBrowse link
G Rorc RAR-related orphan receptor C treatment IEP RGD PMID:32227764 RGD:38549571 NCBI chr 2:195,612,471...195,636,797
Ensembl chr 2:195,617,021...195,637,630
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 16108
    Pathological Conditions, Signs and Symptoms 8726
      Pathologic Processes 6130
        Dysbiosis 5
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.