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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Myocardial Reperfusion Injury
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Accession:DOID:9007838 term browser browse the term
Definition:Damage to the MYOCARDIUM resulting from MYOCARDIAL REPERFUSION (restoration of blood flow to ischemic areas of the HEART.) Reperfusion takes place when there is spontaneous thrombolysis, THROMBOLYTIC THERAPY, collateral flow from other coronary vascular beds, or reversal of vasospasm.
Synonyms:exact_synonym: Myocardial Ischemic Reperfusion Injury;   Myocardial Reperfusion Injuries
 primary_id: MESH:D015428;   RDO:0006866
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants           Sort by:
 
Myocardial Reperfusion Injury term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc8 ATP binding cassette subfamily C member 8 ISO RGD PMID:18316485 RGD:2301903 NCBI chr 1:102,110,708...102,191,287
Ensembl chr 1:102,110,708...102,191,287
JBrowse link
G Ada adenosine deaminase IDA protein:increased expression RGD PMID:16641873 RGD:1624305 NCBI chr 3:160,115,840...160,139,947
Ensembl chr 3:160,115,842...160,139,947
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing ISO CTD Direct Evidence: therapeutic CTD PMID:16155579 NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488
JBrowse link
G Adrb1 adrenoceptor beta 1 IMP
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:10900253, PMID:17201736 RGD:5129149 NCBI chr 1:277,537,585...277,538,985
Ensembl chr 1:277,537,585...277,538,985
JBrowse link
G Adrb2 adrenoceptor beta 2 IDA RGD PMID:16269402 RGD:1598746 NCBI chr18:57,513,792...57,515,834
Ensembl chr18:57,513,793...57,515,834
JBrowse link
G Ager advanced glycosylation end product-specific receptor IEP protein:increased expression:heart (rat) RGD PMID:16505177 RGD:1625342 NCBI chr20:4,363,152...4,366,079
Ensembl chr20:4,363,152...4,366,079
JBrowse link
G Agl amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase IMP RGD PMID:9281456 RGD:1598779 NCBI chr 2:219,788,234...219,843,189
Ensembl chr 2:219,788,234...219,842,986
JBrowse link
G Agt angiotensinogen ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:2535056, PMID:19166939 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433
JBrowse link
G Agtr1a angiotensin II receptor, type 1a IEP protein:increased expression:myocardium RGD PMID:21078800 RGD:5129194 NCBI chr17:35,907,102...35,958,136
Ensembl chr17:35,907,108...35,958,077
JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 IEP
ISO
protein:decreased expression:mitochondrion: RGD PMID:23685150, PMID:23685150 RGD:10053560, RGD:10053560 NCBI chr  X:135,304,063...135,343,062
Ensembl chr  X:135,304,066...135,343,087
JBrowse link
G Akt1 AKT serine/threonine kinase 1 IDA protein:increased phosphorylation:heart left ventricle RGD PMID:20217242 RGD:5509104 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Akt2 AKT serine/threonine kinase 2 IDA RGD PMID:16418318 RGD:2313347 NCBI chr 1:84,400,939...84,451,223
Ensembl chr 1:84,411,726...84,450,162
JBrowse link
G Alb albumin ISO CTD Direct Evidence: marker/mechanism CTD PMID:9572063 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member IDA RGD PMID:23468836 RGD:7241598 NCBI chr12:40,466,418...40,498,813
Ensembl chr12:40,466,495...40,498,752
JBrowse link
G Alox5 arachidonate 5-lipoxygenase IMP RGD PMID:20011686 RGD:2317527 NCBI chr 4:148,398,004...148,446,308
Ensembl chr 4:148,398,892...148,446,303
JBrowse link
G Angpt2 angiopoietin 2 IEP mRNA, protein:increased expression:myocardium (rat) RGD PMID:12737621 RGD:1601505 NCBI chr16:75,966,480...76,016,147
Ensembl chr16:75,966,352...76,016,195
JBrowse link
G Ank1 ankyrin 1 IDA RGD PMID:9378703 RGD:1599110 NCBI chr16:73,681,422...73,912,605
Ensembl chr16:73,681,422...73,827,488
JBrowse link
G Ank2 ankyrin 2 IDA RGD PMID:9378703 RGD:1599110 NCBI chr 2:231,224,643...231,522,655
Ensembl chr 2:231,226,949...231,648,122
JBrowse link
G Ankrd1 ankyrin repeat domain 1 IEP protein:decreased expression:myocardium RGD PMID:19299913 RGD:5133278 NCBI chr 1:254,726,985...254,745,673
Ensembl chr 1:254,726,969...254,735,548
JBrowse link
G Anxa1 annexin A1 treatment IEP
ISO
protein:increased expression:heart, leukocyte RGD PMID:11641252, PMID:22924634, PMID:22924634 RGD:2306910, RGD:7421655, RGD:7421655 NCBI chr 1:237,893,983...237,910,002
Ensembl chr 1:237,893,966...237,910,012
JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 IEP protein:altered localization:cytoplasm RGD PMID:17602955 RGD:2315672 NCBI chr15:27,849,943...27,852,083
Ensembl chr15:27,849,979...27,852,082
JBrowse link
G Arrb2 arrestin, beta 2 IEP RGD PMID:29016703 RGD:13506827 NCBI chr10:57,040,252...57,048,045
Ensembl chr10:57,040,267...57,048,134
JBrowse link
G Atf3 activating transcription factor 3 IEP RGD PMID:11485922 RGD:7327201 NCBI chr13:109,817,892...109,849,632
Ensembl chr13:109,817,728...109,849,632
JBrowse link
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 ISO CTD Direct Evidence: therapeutic CTD PMID:29702141 NCBI chr 2:204,003,742...204,032,023
Ensembl chr 2:204,003,742...204,032,023
JBrowse link
G Atp2a1 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 IMP RGD PMID:17630344 RGD:13782075 NCBI chr 1:197,855,912...197,875,038 JBrowse link
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 treatment ISO
IEP
CTD Direct Evidence: marker/mechanism CTD PMID:10734148, PMID:28637456 RGD:13782080 NCBI chr12:39,553,903...39,603,326
Ensembl chr12:39,553,903...39,603,326
JBrowse link
G Atp5f1d ATP synthase F1 subunit delta treatment IEP protein:decreased expression:myocardium (rat) RGD PMID:26109848, PMID:25305180 RGD:13792666, RGD:13792676 NCBI chr 7:12,426,807...12,432,120
Ensembl chr 7:12,426,809...12,432,130
JBrowse link
G Bad BCL2-associated agonist of cell death treatment IEP
IDA
protein:increased expression, decreased serine phosphorylation:heart RGD PMID:15339931, PMID:23364609 RGD:2292700, RGD:10053674 NCBI chr 1:222,198,516...222,207,459
Ensembl chr 1:222,198,534...222,207,453
JBrowse link
G Bax BCL2 associated X, apoptosis regulator treatment IEP
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:20026869, PMID:21223820, PMID:25547710 RGD:10054103, RGD:13782178 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator treatment IEP
IDA
RGD PMID:16289365, PMID:20821058, PMID:23364609 RGD:1599484, RGD:11561911, RGD:10053674 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcl2l1 Bcl2-like 1 treatment IDA RGD PMID:12668130 RGD:11035287 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G Becn1 beclin 1 treatment IDA
ISO
RGD PMID:20821058, PMID:20812860 RGD:11561911, RGD:11561944 NCBI chr10:89,209,944...89,225,297
Ensembl chr10:89,209,940...89,225,297
JBrowse link
G Bid BH3 interacting domain death agonist IDA
IEP
protein:increased cleavage:heart: RGD PMID:19940077, PMID:11934844 RGD:2317561, RGD:13782263 NCBI chr 4:153,439,812...153,465,247
Ensembl chr 4:153,442,218...153,465,203
JBrowse link
G Blk BLK proto-oncogene, Src family tyrosine kinase IEP mRNA:increased expression:left ventricle (rat) RGD PMID:17562528 RGD:1642307 NCBI chr15:46,555,552...46,593,778
Ensembl chr15:46,555,188...46,593,653
JBrowse link
G Bnip3 BCL2 interacting protein 3 treatment IMP RGD PMID:16645637 RGD:11561983 NCBI chr 1:211,248,098...211,265,282
Ensembl chr 1:211,248,098...211,265,282
JBrowse link
G Btg2 BTG anti-proliferation factor 2 IEP mRNA:increased expression:heart RGD PMID:12909328 RGD:2289075 NCBI chr13:50,913,185...50,916,944
Ensembl chr13:50,913,180...50,916,982
JBrowse link
G C3 complement C3 IEP protein:increased expression:myocardium RGD PMID:11560858 RGD:1582136 NCBI chr 9:9,721,137...9,747,084
Ensembl chr 9:9,721,105...9,747,167
JBrowse link
G C5 complement C5 treatment IDA
IMP
RGD PMID:9631876, PMID:23067403 RGD:1600666, RGD:7411626 NCBI chr 3:14,049,993...14,113,931
NCBI chr 3:14,206,466...14,229,141
Ensembl chr 3:14,049,995...14,229,080
JBrowse link
G Casp1 caspase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:14998631 NCBI chr 8:2,605,743...2,614,637
Ensembl chr 8:2,604,962...2,614,631
JBrowse link
G Casp12 caspase 12 treatment IEP
ISO
protein:increased activity:myocardium
CTD Direct Evidence: marker/mechanism
CTD PMID:14998631, PMID:19406177, PMID:25547710 RGD:2311458, RGD:13782178 NCBI chr 8:2,658,892...2,686,160
Ensembl chr 8:2,659,865...2,686,160
JBrowse link
G Casp3 caspase 3 treatment IMP
IEP
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:14998631, PMID:18470603, PMID:29538428 RGD:2293314, RGD:13782276 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp7 caspase 7 treatment ISO
IEP
CTD Direct Evidence: marker/mechanism CTD PMID:14998631, PMID:29538428 RGD:13782276 NCBI chr 1:277,190,557...277,242,779
Ensembl chr 1:277,190,964...277,242,774
JBrowse link
G Casp8 caspase 8 ISO
IEP
CTD Direct Evidence: marker/mechanism
protein:increased activity:cardiomyocyte
CTD PMID:14998631, PMID:11934844 RGD:13782263 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 treatment ISO
IEP
CTD Direct Evidence: marker/mechanism
protein:increased activity:cardiomyocyte,endothelial cell
CTD PMID:14998631, PMID:29538428, PMID:11934844 RGD:13782276, RGD:13782263 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Casr calcium-sensing receptor IEP protein:increased expression:ventricular myocardium (rat) RGD PMID:21766206 RGD:7205698 NCBI chr11:67,188,204...67,262,261
Ensembl chr11:67,188,630...67,258,771
JBrowse link
G Cast calpastatin IEP RGD PMID:12482022 RGD:5683872 NCBI chr 2:1,452,111...1,561,669
Ensembl chr 2:1,452,116...1,561,464
JBrowse link
G Cat catalase IEP
ISO
CTD Direct Evidence: therapeutic CTD PMID:21600015, PMID:11510883 RGD:1581149 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cbl Cbl proto-oncogene severity ISO RGD PMID:24583314 RGD:11251947 NCBI chr 8:48,481,256...48,564,775
Ensembl chr 8:48,489,036...48,564,722
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 IEP
ISO
mRNA:increased expression:heart (rat)
CTD Direct Evidence: marker/mechanism
CTD PMID:12087064, PMID:10908159 RGD:8549625 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccr2 C-C motif chemokine receptor 2 ISO protein:decreased expression:monocyte: RGD PMID:15786508 RGD:4892017
G Ccr5 C-C motif chemokine receptor 5 treatment ISO
IEP
protein:decreased expression:blood, monocyte (human) RGD PMID:15786508, PMID:23456481 RGD:4892017, RGD:8552227 NCBI chr 8:133,192,398...133,215,599
Ensembl chr 8:133,197,032...133,215,614
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator treatment IEP RGD PMID:18466417 RGD:11341714 NCBI chr 9:65,534,608...65,586,395
Ensembl chr 9:65,534,704...65,587,251
JBrowse link
G Cnr1 cannabinoid receptor 1 IMP RGD PMID:18771032 RGD:2316217 NCBI chr 5:49,307,584...49,333,064
Ensembl chr 5:49,311,030...49,333,056
JBrowse link
G Cnr2 cannabinoid receptor 2 IMP RGD PMID:17950273 RGD:2316224 NCBI chr 5:154,242,010...154,268,126
Ensembl chr 5:154,260,062...154,268,126
JBrowse link
G Crp C-reactive protein IEP protein:increased expression:serum RGD PMID:21122204 RGD:5128547 NCBI chr13:91,080,448...91,081,358
Ensembl chr13:91,054,974...91,093,713
JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 ISO protein:decreased expression:blood, monocyte RGD PMID:15786508 RGD:4892017 NCBI chr 8:128,740,756...128,754,514
Ensembl chr 8:128,740,756...128,754,514
JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 IMP RGD PMID:11342480 RGD:5135269 NCBI chr14:18,743,678...18,745,457
Ensembl chr14:18,743,685...18,745,457
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 IMP RGD PMID:11342480 RGD:5135269 NCBI chr14:18,731,346...18,733,391
Ensembl chr14:18,731,378...18,733,391
JBrowse link
G Cxcl6 C-X-C motif chemokine ligand 6 IMP RGD PMID:11342480 RGD:5135269 NCBI chr14:18,860,201...18,920,839
Ensembl chr14:18,860,264...18,862,407
JBrowse link
G Cybb cytochrome b-245 beta chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:19207477 NCBI chr  X:14,578,330...14,610,049
Ensembl chr  X:14,578,264...14,612,547
JBrowse link
G Diablo diablo, IAP-binding mitochondrial protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:14998631 NCBI chr12:38,490,230...38,503,344
Ensembl chr12:38,490,230...38,503,330
JBrowse link
G Ece1 endothelin converting enzyme 1 IMP
IEP
RGD PMID:18586023, PMID:12193087 RGD:4892580, RGD:7244160 NCBI chr 5:156,215,469...156,318,652
Ensembl chr 5:156,215,417...156,318,671
JBrowse link
G Edn1 endothelin 1 IEP
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:15642760, PMID:16700825, PMID:18586023 RGD:4892580 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Ednra endothelin receptor type A IMP RGD PMID:18586023 RGD:4892580 NCBI chr19:33,928,356...33,991,703
Ensembl chr19:33,928,356...33,991,703
JBrowse link
G Ednrb endothelin receptor type B IMP RGD PMID:21048781 RGD:4892332 NCBI chr15:88,004,775...88,036,354
Ensembl chr15:88,006,977...88,036,354
JBrowse link
G Egln1 egl-9 family hypoxia-inducible factor 1 susceptibility ISO RGD PMID:20185832 RGD:11251775 NCBI chr19:57,660,194...57,701,158
Ensembl chr19:57,662,278...57,699,113
JBrowse link
G Ephx2 epoxide hydrolase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19834332 NCBI chr15:42,757,241...42,794,211
Ensembl chr15:42,757,235...42,794,279
JBrowse link
G Esr1 estrogen receptor 1 IMP RGD PMID:18314151 RGD:4892299 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Esr2 estrogen receptor 2 ISO RGD PMID:18656630 RGD:5508820 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251
JBrowse link
G Fadd Fas associated via death domain treatment ISO
IEP
RGD PMID:26038570, PMID:26948086 RGD:11341801, RGD:13792504 NCBI chr 1:217,746,176...217,748,581
Ensembl chr 1:217,742,929...217,748,628
JBrowse link
G Fas Fas cell surface death receptor treatment IDA RGD PMID:21316771 RGD:8686424 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase treatment IEP RGD PMID:27129213 RGD:11574725 NCBI chr 4:157,676,336...157,680,322
Ensembl chr 4:157,676,595...157,679,962
JBrowse link
G Gcg glucagon treatment ISO RGD PMID:24125539 RGD:10402369 NCBI chr 3:48,442,635...48,451,650
Ensembl chr 3:48,442,635...48,451,650
JBrowse link
G Gja1 gap junction protein, alpha 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17445419 NCBI chr20:37,876,650...37,889,097
Ensembl chr20:37,876,650...37,889,089
JBrowse link
G Glrx glutaredoxin IEP mRNA:decreased expression:heart: RGD PMID:18163565 RGD:2306160 NCBI chr 2:2,606,032...2,615,944
Ensembl chr 2:2,605,996...2,615,944
JBrowse link
G Grk2 G protein-coupled receptor kinase 2 treatment
severity
susceptibility
IMP
ISO
IDA
associated with Diabetes Mellitus, Experimental
protein:increased expression:heart, mitochondrion (mouse)
associated with Hypertension
RGD PMID:27865836, PMID:23467820, PMID:24170934, PMID:27296507, PMID:27601479 RGD:13513990, RGD:13792779, RGD:13792704, RGD:13513995, RGD:13513993 NCBI chr 1:219,536,220...219,544,329
Ensembl chr 1:219,536,220...219,544,328
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta treatment IDA
IEP
RGD PMID:20217242, PMID:26918336, PMID:29978610 RGD:5509104, RGD:13792772, RGD:13792725 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
JBrowse link
G Gsr glutathione-disulfide reductase treatment IEP RGD PMID:24769323 RGD:10401892 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G H2ax H2A.X variant histone treatment IDA RGD PMID:23108649 RGD:8693739 NCBI chr 8:48,665,652...48,666,981
Ensembl chr 8:48,665,652...48,666,981
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha treatment IEP
ISO
IDA
mRNA:increased expression:heart
CTD Direct Evidence: marker/mechanism
protein:increased expression:myocardium
CTD PMID:18549825, PMID:22050707, PMID:12189448, PMID:20170615, PMID:19727523 RGD:1626327, RGD:9068872, RGD:5147885 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Hmgb1 high mobility group box 1 treatment IEP
ISO
IDA
CTD Direct Evidence: marker/mechanism CTD PMID:21113057, PMID:23531454, PMID:19540007 RGD:10402066, RGD:10402170 NCBI chr12:7,082,529...7,090,246
Ensembl chr16:37,500,017...37,502,237
JBrowse link
G Hmox1 heme oxygenase 1 treatment IDA
ISO
IEP
RGD PMID:12709584, PMID:23921302, PMID:22179023 RGD:1598392, RGD:10755585, RGD:10755573 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hrh2 histamine receptor H 2 susceptibility ISO RGD PMID:23467745 RGD:9685524 NCBI chr17:10,912,959...10,931,389
Ensembl chr17:10,921,507...10,952,441
JBrowse link
G Hrh3 histamine receptor H3 IDA RGD PMID:15076218 RGD:1626433 NCBI chr 3:175,474,310...175,479,395
Ensembl chr 3:175,473,078...175,479,395
JBrowse link
G Hsf1 heat shock transcription factor 1 ISO RGD PMID:22426029 RGD:10402789 NCBI chr 7:117,538,523...117,565,478
Ensembl chr 7:117,538,523...117,565,478
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 treatment IEP RGD PMID:24129401, PMID:25547710 RGD:11354962, RGD:13782178 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
JBrowse link
G Htra2 HtrA serine peptidase 2 ISO protein:increased expression:myocardium, cytosol (mouse) RGD PMID:15611365 RGD:5688376 NCBI chr 4:113,883,671...113,886,833
Ensembl chr 4:113,883,670...113,886,994
JBrowse link
G Icam1 intercellular adhesion molecule 1 IEP
ISO
protein:increased expression:heart (rat)
CTD Direct Evidence: marker/mechanism
CTD PMID:12087064, PMID:20851484 RGD:4145348 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Il10 interleukin 10 treatment IEP
IDA
protein:increased expression:plasma RGD PMID:19275881, PMID:23840272 RGD:2311056, RGD:7365001 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il17a interleukin 17A treatment IMP RGD PMID:22030025 RGD:9068944 NCBI chr 9:26,841,299...26,844,786
Ensembl chr 9:26,841,299...26,844,786
JBrowse link
G Il18 interleukin 18 ISO
IDA
RGD PMID:19164288, PMID:19805173 RGD:4889578, RGD:4889400 NCBI chr 8:55,009,666...55,016,286
Ensembl chr 8:54,993,859...55,016,299
JBrowse link
G Il18bp interleukin 18 binding protein ISO mRNA:increased expression:heart RGD PMID:19164288, PMID:19805173 RGD:4889578, RGD:4889400 NCBI chr 1:167,091,521...167,095,727
Ensembl chr 1:167,091,522...167,093,560
JBrowse link
G Il18rap interleukin 18 receptor accessory protein ISO RGD PMID:19164288 RGD:4889578 NCBI chr 9:47,225,543...47,255,805
Ensembl chr 9:47,225,585...47,258,503
JBrowse link
G Il1a interleukin 1 alpha treatment ISO
IEP
RGD PMID:8576926, PMID:7622355 RGD:7794741, RGD:7794764 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il1b interleukin 1 beta IEP mRNA:increased expression:heart RGD PMID:17134725 RGD:1626628 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il1rn interleukin 1 receptor antagonist ISO rat model treated with human protein RGD PMID:22649318 RGD:7174360 NCBI chr 3:1,449,778...1,468,624
Ensembl chr 3:1,452,644...1,468,614
JBrowse link
G Il6 interleukin 6 treatment IDA RGD PMID:27087891 RGD:11062149 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Il6r interleukin 6 receptor ISO RGD PMID:16056242 RGD:1625435 NCBI chr 2:189,196,180...189,255,987
Ensembl chr 2:189,205,701...189,254,628
JBrowse link
G Irak1 interleukin-1 receptor-associated kinase 1 IEP protein:increased activity:ventricle myocardium (rat) RGD PMID:15793310 RGD:1579809 NCBI chr  X:156,716,469...156,726,367
Ensembl chr  X:156,716,604...156,725,977
JBrowse link
G Jak2 Janus kinase 2 treatment IMP associated with Diabetes Mellitus, Experimental RGD PMID:23796350, PMID:23747931 RGD:8694332, RGD:10403071 NCBI chr 1:247,398,667...247,457,521
Ensembl chr 1:247,398,598...247,458,509
JBrowse link
G Kcnj11 potassium inwardly-rectifying channel, subfamily J, member 11 ISO RGD PMID:17906066 RGD:7297046 NCBI chr 1:102,103,093...102,107,134
Ensembl chr 1:102,103,094...102,106,127
JBrowse link
G Kcnj8 potassium inwardly-rectifying channel, subfamily J, member 8 IDA RGD PMID:12234964 RGD:729109 NCBI chr 4:176,783,287...176,789,143
Ensembl chr 4:176,782,498...176,789,304
JBrowse link
G Klrk1 killer cell lectin like receptor K1 treatment IMP RGD PMID:23953572 RGD:9685183 NCBI chr 4:163,392,652...163,403,735
Ensembl chr 4:163,393,217...163,403,653
JBrowse link
G Kng2 kininogen 2 ISO CTD Direct Evidence: therapeutic CTD PMID:2535056, PMID:7856280 NCBI chr11:81,509,185...81,516,759 JBrowse link
G Lep leptin IEP RGD PMID:21122204 RGD:5128547 NCBI chr 4:56,337,695...56,351,818
Ensembl chr 4:56,337,695...56,351,818
JBrowse link
G Lepr leptin receptor IEP mRNA:decreased expression:heart
mRNA:altered expression:heart:
RGD PMID:15284063, PMID:17134725 RGD:5129123, RGD:1626628 NCBI chr 5:120,503,475...120,682,281
Ensembl chr 5:120,564,645...120,682,221
JBrowse link
G Lum lumican IDA RGD PMID:11348051 RGD:1582122 NCBI chr 7:38,820,058...38,826,862
Ensembl chr 7:38,819,771...38,826,862
JBrowse link
G Map1lc3a microtubule-associated protein 1 light chain 3 alpha treatment IEP
ISO
protein:increased expression:heart RGD PMID:20821058, PMID:20812860 RGD:11561911, RGD:11561944 NCBI chr 3:150,801,289...150,802,935
Ensembl chr 3:150,801,289...150,802,935
JBrowse link
G Map2k6 mitogen-activated protein kinase kinase 6 ISO RGD PMID:14749328, PMID:15492008 RGD:7495840, RGD:1582277 NCBI chr10:98,707,160...98,823,054
Ensembl chr10:98,706,960...98,823,287
JBrowse link
G Mapk1 mitogen activated protein kinase 1 treatment IDA RGD PMID:15653762, PMID:25345742 RGD:1582282, RGD:13800900 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk14 mitogen activated protein kinase 14 ISO RGD PMID:14749328 RGD:7495840 NCBI chr20:5,933,290...5,995,137
Ensembl chr20:5,933,303...5,995,137
JBrowse link
G Mapk3 mitogen activated protein kinase 3 treatment IEP
IDA
RGD PMID:29741915, PMID:25345742, PMID:28814571 RGD:13800564, RGD:13800900, RGD:13800874 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 IDA
IEP
RGD PMID:15309413, PMID:12883833 RGD:1582311, RGD:1582312 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Mb myoglobin ISO
IDA
RGD PMID:15132981, PMID:11972171 RGD:1582385, RGD:1582431 NCBI chr 7:118,101,633...118,108,864
Ensembl chr 7:118,101,634...118,108,864
JBrowse link
G Mbl1 mannose binding lectin 1 IDA
IMP
ISO
RGD PMID:11560858, PMID:20216929, PMID:15972690 RGD:1582136, RGD:4889154, RGD:1582131 NCBI chr16:18,736,154...18,742,193
Ensembl chr16:18,736,154...18,742,193
JBrowse link
G Mbl2 mannose binding lectin 2 treatment ISO RGD PMID:25482922 RGD:11530049 NCBI chr 1:248,435,069...248,442,669
Ensembl chr 1:248,723,397...248,729,962
JBrowse link
G Mdm2 MDM2 proto-oncogene IEP protein:increased serine phosphorylation:heart ventricle (rat) RGD PMID:14644432 RGD:2317401 NCBI chr 7:60,719,060...60,743,618
Ensembl chr 7:60,719,066...60,743,328
JBrowse link
G Mfn2 mitofusin 2 treatment IEP RGD PMID:24721408 RGD:13204835 NCBI chr 5:164,684,244...164,715,414
Ensembl chr 5:164,684,509...164,714,145
JBrowse link
G Mir1 microRNA 1 treatment IMP RGD PMID:29741915 RGD:13800564 NCBI chr18:2,054,933...2,055,019 JBrowse link
G Mir10a microRNA 10a ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr10:84,165,950...84,166,059
Ensembl chr10:84,165,950...84,166,059
JBrowse link
G Mir10b microRNA 10b ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr 3:61,647,978...61,648,086
Ensembl chr 3:61,647,978...61,648,086
JBrowse link
G Mir126b microRNA 126b ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr 3:4,042,488...4,042,560 JBrowse link
G Mir134 microRNA 134 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr 6:133,884,547...133,884,619
Ensembl chr 6:133,884,531...133,884,633
JBrowse link
G Mir137 microRNA 137 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr 2:221,658,106...221,658,207
Ensembl chr 2:221,658,106...221,658,207
JBrowse link
G Mir142 microRNA 142 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr10:75,050,839...75,050,925
Ensembl chr10:75,050,832...75,050,942
JBrowse link
G Mir181c microRNA 181c ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr19:25,290,211...25,290,316
Ensembl chr19:25,290,211...25,290,316
JBrowse link
G Mir183 microRNA 183 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr 4:57,463,569...57,463,678
Ensembl chr 4:57,463,569...57,463,678
JBrowse link
G Mir186 microRNA 186 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr 2:263,873,759...263,873,844
Ensembl chr 2:263,873,759...263,873,844
JBrowse link
G Mir188 microRNA 188 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr  X:16,110,270...16,110,349
Ensembl chr  X:16,110,270...16,110,349
JBrowse link
G Mir193a microRNA 193a ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr10:67,065,885...67,065,996
Ensembl chr10:67,065,885...67,065,996
JBrowse link
G Mir196b microRNA 196b ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr 4:82,199,056...82,199,140
Ensembl chr 4:82,199,056...82,199,140
JBrowse link
G Mir206 microRNA 206 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr 9:26,791,764...26,791,847
Ensembl chr 9:26,791,764...26,791,847
JBrowse link
G Mir20b microRNA 20b ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr  X:140,117,518...140,117,589
Ensembl chr  X:140,117,518...140,117,589
JBrowse link
G Mir21 microRNA 21 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr10:73,902,210...73,902,301
Ensembl chr10:73,902,210...73,902,301
JBrowse link
G Mir23b microRNA 23b ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr17:823,222...823,318
Ensembl chr17:823,222...823,318
JBrowse link
G Mir26a microRNA 26a treatment IEP RGD PMID:29978610 RGD:13792725 NCBI chr 8:127,714,441...127,714,530
Ensembl chr 8:127,714,441...127,714,530
JBrowse link
G Mir27a microRNA 27a ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr19:25,318,736...25,318,822
Ensembl chr19:25,318,736...25,318,822
JBrowse link
G Mir27b microRNA 27b ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr17:823,461...823,557
Ensembl chr17:823,461...823,557
JBrowse link
G Mir28 microRNA 28 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr11:79,380,523...79,380,608
Ensembl chr11:79,380,523...79,380,608
JBrowse link
G Mir296 microRNA 296 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr 3:172,357,490...172,357,567
Ensembl chr 3:172,357,490...172,357,567
JBrowse link
G Mir301b microRNA 301b ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr11:88,129,426...88,129,503
Ensembl chr11:88,129,426...88,129,503
JBrowse link
G Mir30a microRNA 30a treatment IEP RGD PMID:25137026 RGD:35673319 NCBI chr 9:29,542,635...29,542,705
Ensembl chr 9:29,542,635...29,542,705
JBrowse link
G Mir330 microRNA 330 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr 1:80,092,681...80,092,777
Ensembl chr 1:80,092,681...80,092,777
JBrowse link
G Mir331 microRNA 331 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr 7:34,881,095...34,881,190
Ensembl chr 7:34,881,095...34,881,190
JBrowse link
G Mir337 microRNA 337 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr 6:133,705,920...133,706,016
Ensembl chr 6:133,705,920...133,706,016
JBrowse link
G Mir346 microRNA 346 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr16:11,250,054...11,250,151
Ensembl chr16:11,250,054...11,250,151
JBrowse link
G Mir34c microRNA 34c ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr 8:55,492,024...55,492,100
Ensembl chr 8:55,492,024...55,492,100
JBrowse link
G Mir361 microRNA 361 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr  X:84,708,911...84,708,980
Ensembl chr  X:84,708,911...84,708,980
JBrowse link
G Mir375 microRNA 375 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr 9:82,161,716...82,161,790
Ensembl chr 9:82,161,716...82,161,790
JBrowse link
G Mir411 microRNA 411 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr 6:133,858,849...133,858,924
Ensembl chr 6:133,858,844...133,858,939
JBrowse link
G Mir429 microRNA 429 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr 5:173,488,331...173,488,415
Ensembl chr 5:173,488,331...173,488,415
JBrowse link
G Mir433 microRNA 433 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr 6:133,712,334...133,712,426
Ensembl chr 6:133,712,334...133,712,426
JBrowse link
G Mir451a microRNA 451a ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr10:65,291,204...65,291,275
Ensembl chr10:65,291,204...65,291,275
JBrowse link
G Mir500 microRNA 500 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr  X:16,121,332...16,121,411
Ensembl chr  X:16,121,322...16,121,413
JBrowse link
G Mir503 microRNA 503 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr  X:158,148,476...158,148,546
Ensembl chr  X:158,148,476...158,148,546
JBrowse link
G Mir532 microRNA 532 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr  X:16,109,870...16,109,948
Ensembl chr  X:16,109,870...16,109,948
JBrowse link
G Mir542 microRNA 542 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr  X:158,152,146...158,152,224
Ensembl chr  X:158,152,146...158,152,224
JBrowse link
G Mir582 microRNA 582 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr 2:40,863,750...40,863,830
Ensembl chr 2:40,863,750...40,863,830
JBrowse link
G Mir598 microRNA 598 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr15:47,057,496...47,057,574
Ensembl chr15:47,057,496...47,057,575
JBrowse link
G Mir743a microRNA 743a EXP CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr  X:151,252,828...151,252,903
Ensembl chr  X:151,252,828...151,252,903
JBrowse link
G Mirlet7i microRNA let-7i ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr 7:66,802,731...66,802,815
Ensembl chr 7:66,802,732...66,802,821
JBrowse link
G Mki67 marker of proliferation Ki-67 IDA RGD PMID:22405128 RGD:6483543 NCBI chr 1:207,993,895...208,020,454
Ensembl chr 1:207,993,895...208,020,454
JBrowse link
G Mmp1 matrix metallopeptidase 1 ISO
IEP
RGD PMID:12892382, PMID:17996137 RGD:1582539, RGD:7207397 NCBI chr 8:5,703,206...5,723,593
Ensembl chr 8:5,703,206...5,723,591
JBrowse link
G Mmp2 matrix metallopeptidase 2 treatment ISO
IEP
RGD PMID:16699069, PMID:23889688 RGD:1582614, RGD:8657084 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor IDA RGD PMID:14962484 RGD:1302746 NCBI chr 8:128,022,512...128,027,462
Ensembl chr 8:128,022,473...128,026,841
JBrowse link
G Ncl nucleolin IEP protein:decreased expression:heart RGD PMID:23594402 RGD:9686384 NCBI chr 9:93,369,119...93,377,643
Ensembl chr 9:93,368,932...93,377,643
JBrowse link
G Ndufs1 NADH:ubiquinone oxidoreductase core subunit S1 treatment IDA RGD PMID:21700931 RGD:13801200 NCBI chr 9:69,919,863...69,953,182
Ensembl chr 9:69,919,867...69,953,182
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 ISO RGD PMID:24915518 RGD:10412738 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nfkbia NFKB inhibitor alpha treatment IDA RGD PMID:19304943 RGD:10413871 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Nos2 nitric oxide synthase 2 IEP
ISO
mRNA:decreased expression:heart (rat)
CTD Direct Evidence: marker/mechanism|therapeutic
CTD PMID:12003803, PMID:12087064, PMID:14990356, PMID:19207477, PMID:20828608, PMID:21844074 RGD:5509098 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Nos3 nitric oxide synthase 3 treatment IEP
IDA
ISO
IMP
CTD Direct Evidence: therapeutic CTD PMID:12354446, PMID:20828747, PMID:29274587, PMID:29299201, PMID:18390819 RGD:4891991, RGD:13504684, RGD:13503347, RGD:2292091 NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410
JBrowse link
G Nppb natriuretic peptide B IDA RGD PMID:21168723 RGD:5685663 NCBI chr 5:164,796,176...164,797,538
Ensembl chr 5:164,796,185...164,797,531
JBrowse link
G Nppc natriuretic peptide C IDA RGD PMID:15337698 RGD:1580149 NCBI chr 9:93,731,436...93,735,636
Ensembl chr 9:93,731,436...93,735,636
JBrowse link
G Npr3 natriuretic peptide receptor 3 IDA RGD PMID:15337698 RGD:1580149 NCBI chr 2:61,883,946...61,950,291
Ensembl chr 2:61,888,950...61,949,926
JBrowse link
G Npy1r neuropeptide Y receptor Y1 IEP mRNA:decreased expression:heart left ventricle RGD PMID:17562528 RGD:1642307 NCBI chr16:24,779,480...24,789,131
Ensembl chr16:24,779,477...24,788,740
JBrowse link
G Olr1 oxidized low density lipoprotein receptor 1 treatment IMP RGD PMID:12384456 RGD:628368 NCBI chr 4:163,239,853...163,261,937
Ensembl chr 4:163,239,849...163,261,958
JBrowse link
G Oprd1 opioid receptor, delta 1 IDA RGD PMID:12136724 RGD:2316590 NCBI chr 5:150,288,126...150,323,063
Ensembl chr 5:150,288,126...150,323,063
JBrowse link
G Oxt oxytocin/neurophysin I prepropeptide IMP RGD PMID:19234577 RGD:2304087 NCBI chr 3:123,106,694...123,107,534
Ensembl chr 3:123,106,694...123,107,534
JBrowse link
G P2ry12 purinergic receptor P2Y12 ISO RGD PMID:20431845 RGD:6480645 NCBI chr 2:149,440,807...149,482,592
Ensembl chr 2:149,441,598...149,444,548
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 ISO RGD PMID:9670921, PMID:23598272 RGD:5683917, RGD:11073735 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Pawr pro-apoptotic WT1 regulator treatment IMP RGD PMID:18055876 RGD:9835369 NCBI chr 7:51,273,764...51,353,700
Ensembl chr 7:51,273,771...51,353,068
JBrowse link
G Pdia3 protein disulfide isomerase family A, member 3 IEP RGD PMID:12872233 RGD:1624250 NCBI chr 3:113,376,983...113,400,707
Ensembl chr 3:113,376,983...113,400,707
JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 IMP RGD PMID:8989147 RGD:2311662 NCBI chr10:94,850,971...94,913,202 JBrowse link
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma ISO RGD PMID:20179753 RGD:6482687 NCBI chr 6:51,465,696...51,501,234
Ensembl chr 6:51,465,908...51,498,337
JBrowse link
G Plcd1 phospholipase C, delta 1 IDA protein:altered activity RGD PMID:12623065 RGD:1304368 NCBI chr 8:127,753,514...127,782,070
Ensembl chr 8:127,753,539...127,782,070
JBrowse link
G Pld2 phospholipase D2 IDA protein:altered activity:sarcolemma, sarcoplasmic reticulum, heart left ventricle RGD PMID:15752718 RGD:2299906 NCBI chr10:57,161,921...57,181,148
Ensembl chr10:57,163,174...57,179,730
JBrowse link
G Pln phospholamban treatment IDA
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:10734148, PMID:21934351 RGD:7327186 NCBI chr20:34,633,157...34,642,904
Ensembl chr20:34,633,157...34,642,904
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha ISO CTD Direct Evidence: therapeutic CTD PMID:16411023 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
JBrowse link
G Ppard peroxisome proliferator-activated receptor delta IDA RGD PMID:19997057 RGD:2324876 NCBI chr20:7,818,289...7,883,482
Ensembl chr20:7,818,289...7,885,333
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma ISO RGD PMID:18562925 RGD:2301853 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha treatment ISO RGD PMID:19096023 RGD:10059669 NCBI chr14:63,095,291...63,190,688
Ensembl chr14:63,095,720...63,187,009
JBrowse link
G Prkcb protein kinase C, beta IDA RGD PMID:15878997 RGD:1625520 NCBI chr 1:192,233,569...192,575,339
Ensembl chr 1:192,233,910...192,574,831
JBrowse link
G Prkcd protein kinase C, delta IEP protein:decreased expression:heart RGD PMID:17322024 RGD:1642542 NCBI chr16:6,655,131...6,675,746
Ensembl chr16:6,655,120...6,675,746
JBrowse link
G Prkg1 protein kinase cGMP-dependent 1 treatment IMP RGD PMID:18332860, PMID:19845676 RGD:7777120, RGD:7777130 NCBI chr 1:248,982,039...250,300,952 JBrowse link
G Procr protein C receptor treatment IDA RGD PMID:26994471 RGD:13515126 NCBI chr 3:151,285,321...151,289,581
Ensembl chr 3:151,285,249...151,289,595
JBrowse link
G Pten phosphatase and tensin homolog ISO CTD Direct Evidence: marker/mechanism CTD PMID:19038262 NCBI chr 1:251,421,814...251,487,634
Ensembl chr 1:251,421,596...251,487,832
JBrowse link
G Ptger3 prostaglandin E receptor 3 treatment IMP RGD PMID:10193764 RGD:10043342 NCBI chr 2:263,895,093...263,979,682
Ensembl chr 2:263,895,241...263,979,698
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 IMP RGD PMID:17660401 RGD:2300261 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Rap1a RAP1A, member of RAS oncogene family treatment IDA RGD PMID:20501665 RGD:10003160 NCBI chr 2:208,193,950...208,215,186
Ensembl chr 2:208,193,954...208,215,187
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit IDA protein:altered localization:nucleus RGD PMID:18636044 RGD:2298773 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Rhoa ras homolog family member A IEP protein:altered localization:heart RGD PMID:17322412 RGD:1642967 NCBI chr 8:117,082,440...117,116,244
Ensembl chr 8:117,106,576...117,116,167
JBrowse link
G Rnls renalase, FAD-dependent amine oxidase ISO RGD PMID:21178975, PMID:21178975 RGD:7327174, RGD:7327174 NCBI chr 1:251,828,285...252,101,963
Ensembl chr 1:251,828,290...252,100,759
JBrowse link
G S100b S100 calcium binding protein B IEP mRNA, protein:increased expression:myocardium RGD PMID:21663912 RGD:5508825 NCBI chr20:13,130,633...13,142,856
Ensembl chr20:13,130,636...13,142,856
JBrowse link
G Selp selectin P IEP
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:12087064, PMID:21146547 RGD:6480105 NCBI chr13:82,428,914...82,464,629
Ensembl chr13:82,429,063...82,464,628
JBrowse link
G Serpina3m serpin family A member 3M ISO RGD PMID:7562495 RGD:5147423 NCBI chr 6:127,808,785...127,816,067
Ensembl chr 6:127,808,785...127,816,055
JBrowse link
G Serpina3n serine (or cysteine) peptidase inhibitor, clade A, member 3N ISO RGD PMID:7562495 RGD:5147423 NCBI chr 6:128,073,344...128,080,878
Ensembl chr 6:127,941,526...128,080,889
JBrowse link
G Serpine1 serpin family E member 1 treatment IDA RGD PMID:26958805 RGD:11073621 NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482
JBrowse link
G Serping1 serpin family G member 1 treatment ISO RGD PMID:16942749 RGD:8661647 NCBI chr 3:72,161,230...72,171,109
Ensembl chr 3:72,161,189...72,171,078
JBrowse link
G Sfrp2 secreted frizzled-related protein 2 IEP RGD PMID:19109969 RGD:4107088 NCBI chr 2:182,723,732...182,731,277
Ensembl chr 2:182,723,854...182,731,764
JBrowse link
G Sh2b3 SH2B adaptor protein 3 IMP RGD PMID:25628389 RGD:12904914 NCBI chr12:40,261,990...40,265,757
Ensembl chr12:40,244,081...40,265,757
JBrowse link
G Sh2b3em2Mcwi SH2B adaptor protein 3; zinc finger nuclease induced mutant 2, Medical College of Wisconsin IMP RGD PMID:25628389 RGD:12904914
G Shh sonic hedgehog signaling molecule IEP protein:increased expression:heart RGD PMID:18228117 RGD:2306299 NCBI chr 4:718,538...727,691
Ensembl chr 4:718,538...727,691
JBrowse link
G Sirt1 sirtuin 1 ISO CTD Direct Evidence: therapeutic CTD PMID:21060073 NCBI chr20:26,831,971...26,851,587
Ensembl chr20:26,833,357...26,852,199
JBrowse link
G Slc25a4 solute carrier family 25 member 4 treatment IEP RGD PMID:24126566 RGD:9681554 NCBI chr16:49,266,903...49,270,698
Ensembl chr16:49,266,903...49,270,698
JBrowse link
G Slc2a1 solute carrier family 2 member 1 IEP RGD PMID:10336852 RGD:12879857 NCBI chr 5:138,154,677...138,182,897
Ensembl chr 5:138,154,673...138,182,897
JBrowse link
G Slc2a4 solute carrier family 2 member 4 IEP RGD PMID:10336852 RGD:12879857 NCBI chr10:56,552,921...56,558,562
Ensembl chr10:56,552,983...56,558,487
JBrowse link
G Slc8a1 solute carrier family 8 member A1 IDA
ISO
IMP
CTD Direct Evidence: marker/mechanism
protein:increased activity:cardiac muscle cell
CTD PMID:15215644, PMID:17267548, PMID:17822695 RGD:1642729, RGD:1642716 NCBI chr 6:4,244,076...4,564,262
Ensembl chr 6:4,258,991...4,520,604
JBrowse link
G Slc9a1 solute carrier family 9 member A1 IMP RGD PMID:22803959 RGD:6771238 NCBI chr 5:151,573,122...151,626,360
Ensembl chr 5:151,573,092...151,627,316
JBrowse link
G Smad1 SMAD family member 1 ISO RGD PMID:15911698 RGD:1643233 NCBI chr19:32,182,942...32,248,694
Ensembl chr19:32,188,267...32,248,684
JBrowse link
G Smad3 SMAD family member 3 treatment IDA RGD PMID:22913380 RGD:12903950 NCBI chr 8:68,569,530...68,678,349
Ensembl chr 8:68,569,530...68,678,349
JBrowse link
G Smad4 SMAD family member 4 treatment IEP RGD PMID:22913380 RGD:12903950 NCBI chr18:69,626,682...69,657,373
Ensembl chr18:69,627,757...69,671,199
JBrowse link
G Sod1 superoxide dismutase 1 treatment ISO
IDA
human protein in a rat model RGD PMID:19277497, PMID:12668130, PMID:23629152 RGD:8655884, RGD:11035287, RGD:8655965 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
G Sod2 superoxide dismutase 2 treatment ISO RGD PMID:11864929, PMID:12668130 RGD:1581222, RGD:11035287 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Sord sorbitol dehydrogenase IEP
ISO
protein:increased activity:heart
CTD Direct Evidence: marker/mechanism
CTD PMID:18549825, PMID:14525943 RGD:1601364 NCBI chr 3:114,176,127...114,207,368
Ensembl chr 3:114,176,309...114,207,366
JBrowse link
G Spp1 secreted phosphoprotein 1 ISO RGD PMID:15165989 RGD:1581342 NCBI chr14:6,673,686...6,679,965
Ensembl chr14:6,673,686...6,679,901
JBrowse link
G Stat1 signal transducer and activator of transcription 1 IDA protein:increased phosphorylation:heart RGD PMID:16935931 RGD:1600091 NCBI chr 9:54,287,540...54,327,958
Ensembl chr 9:54,287,541...54,484,533
JBrowse link
G Stat3 signal transducer and activator of transcription 3 treatment IDA RGD PMID:23796350 RGD:8694332 NCBI chr10:88,790,401...88,842,263
Ensembl chr10:88,790,408...88,842,233
JBrowse link
G Suv39h1 suppressor of variegation 3-9 homolog 1 treatment IDA associated with Diabetes Mellitus, Experimental RGD PMID:24752040 RGD:9586740 NCBI chr  X:146,532,002...146,533,538 JBrowse link
G Tek TEK receptor tyrosine kinase IEP mRNA, protein:increased expression:ventricle myocardium RGD PMID:12737621 RGD:1601505 NCBI chr 5:113,725,717...113,852,799
Ensembl chr 5:113,725,717...113,852,799
JBrowse link
G Tfrc transferrin receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:18549825 NCBI chr11:71,397,423...71,419,263
Ensembl chr11:71,397,383...71,419,223
JBrowse link
G Tgfb1 transforming growth factor, beta 1 treatment IEP RGD PMID:22913380 RGD:12903950 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Thbs1 thrombospondin 1 IEP mRNA:increased expression:heart RGD PMID:16179730 RGD:2317960 NCBI chr 3:109,862,120...109,873,466
Ensembl chr 3:109,862,117...109,873,466
JBrowse link
G Timp4 TIMP metallopeptidase inhibitor 4 IEP protein:increased expression:blood RGD PMID:12707244 RGD:2290461 NCBI chr 4:147,156,948...147,163,467
Ensembl chr 4:147,156,948...147,163,467
JBrowse link
G Tlr2 toll-like receptor 2 IEP RGD PMID:19274437 RGD:2312688 NCBI chr 2:182,840,171...182,846,061
Ensembl chr 2:182,840,727...182,846,061
JBrowse link
G Tlr4 toll-like receptor 4 IDA RGD PMID:14962484 RGD:1302746 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052
JBrowse link
G Tnc tenascin C IEP RGD PMID:20554738 RGD:4889599 NCBI chr 5:79,789,686...79,874,555
Ensembl chr 5:79,789,671...79,874,671
JBrowse link
G Tnf tumor necrosis factor IEP protein:increased expression:serum, heart: RGD PMID:24157164 RGD:7387274 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tp53 tumor protein p53 IEP protein:increased expression:heart RGD PMID:18317410 RGD:2290554 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Txn1 thioredoxin 1 IEP mRNA:decreased expression:heart RGD PMID:18045550 RGD:2306159 NCBI chr 5:75,049,735...75,057,731
Ensembl chr 5:75,049,747...75,057,752
JBrowse link
G Txn2 thioredoxin 2 IEP mRNA, protein:decreased expression:heart RGD PMID:18045550 RGD:2306159 NCBI chr 7:119,144,350...119,158,173
Ensembl chr 7:119,144,351...119,158,201
JBrowse link
G Ucn urocortin IDA RGD PMID:15806110 RGD:1642783 NCBI chr 6:26,602,144...26,602,974
Ensembl chr 6:26,602,144...26,602,974
JBrowse link
G Ucp2 uncoupling protein 2 IEP mRNA:increased expression:myocardium RGD PMID:19526854 RGD:2313528 NCBI chr 1:165,506,375...165,512,744
Ensembl chr 1:165,506,361...165,512,744
JBrowse link
G Ucp3 uncoupling protein 3 IEP mRNA:increased expression:myocardium RGD PMID:19526854 RGD:2313528 NCBI chr 1:165,482,912...165,495,895
Ensembl chr 1:165,482,155...165,496,206
JBrowse link
G Uts2 urotensin 2 IDA RGD PMID:17900760 RGD:2306836 NCBI chr 5:168,078,748...168,084,133
Ensembl chr 5:168,078,748...168,084,145
JBrowse link
G Uts2r urotensin 2 receptor IMP RGD PMID:17900760 RGD:2306836 NCBI chr10:110,364,291...110,365,451
Ensembl chr10:110,364,291...110,365,451
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 IEP protein:increased expression:heart RGD PMID:23052973 RGD:7207792 NCBI chr 2:219,071,193...219,090,931
Ensembl chr 2:219,071,193...219,097,619
JBrowse link
G Vcan versican IEP mRNA:increased expression:heart RGD PMID:16311904 RGD:1598497 NCBI chr 2:18,490,102...18,587,340
Ensembl chr 2:18,490,102...18,565,842
JBrowse link
G Vdac1 voltage-dependent anion channel 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25488258 NCBI chr10:37,724,915...37,752,827
Ensembl chr10:37,724,915...37,752,826
JBrowse link
G Vdr vitamin D receptor ISO mRNA,protein:increased expression, activity:heart: RGD PMID:25365634 RGD:13432076 NCBI chr 7:139,344,452...139,394,138
Ensembl chr 7:139,342,063...139,394,166
JBrowse link
G Vegfa vascular endothelial growth factor A ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
G Xdh xanthine dehydrogenase IEP RGD PMID:3162724 RGD:13209131 NCBI chr 6:25,149,570...25,211,273
Ensembl chr 6:25,149,235...25,211,494
JBrowse link
G Xiap X-linked inhibitor of apoptosis ISO CTD Direct Evidence: marker/mechanism CTD PMID:14998631 NCBI chr  X:128,409,425...128,455,786
Ensembl chr  X:128,409,472...128,453,000
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 16108
    disease of anatomical entity 15356
      cardiovascular system disease 4484
        heart disease 2667
          cardiomyopathy 1088
            Myocardial Reperfusion Injury 257
Path 2
Term Annotations click to browse term
  disease 16108
    disease of anatomical entity 15356
      cardiovascular system disease 4484
        vascular disease 3415
          ischemia 1295
            Myocardial Ischemia 809
              Myocardial Reperfusion Injury 257
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.