ONTOLOGY REPORT - ANNOTATIONS


Term:Arsenic Poisoning
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Accession:DOID:9007964 term browser browse the term
Definition:Disorders associated with acute or chronic exposure to compounds containing ARSENIC (ARSENICALS) which may be fatal. Acute oral ingestion is associated with gastrointestinal symptoms and an encephalopathy which may manifest as SEIZURES, mental status changes, and COMA. Chronic exposure is associated with mucosal irritation, desquamating rash, myalgias, peripheral neuropathy, and white transverse (Mees) lines in the fingernails. (Adams et al., Principles of Neurology, 6th ed, p1212)
Synonyms:exact_synonym: Arsenic Encephalopathies;   Arsenic Encephalopathy;   Arsenic Induced Polyneuropathy;   Arsenic Poisoning, Nervous System;   Arsenic Poisonings;   Arsenic-Induced Polyneuropathies;   Arsenical Neurotoxicity Syndrome;   Arsenical Neurotoxicity Syndromes;   Inorganic Arsenic Poisoning;   Inorganic Arsenic Poisonings;   Nervous System, Organic Arsenic Poisoning;   Organic Arsenic Poisoning;   Organic Arsenic Poisonings
 primary_id: MESH:D020261;   RDO:0007378
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Arsenic Poisoning term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akap9 A-kinase anchoring protein 9 JBrowse link 4 27,195,346 27,331,582 RGD:11554173
G Alad aminolevulinate dehydratase JBrowse link 5 78,368,867 78,379,206 RGD:4144202
G Aqp9 aquaporin 9 JBrowse link 8 77,559,621 77,599,781 RGD:11554173
G As3mt arsenite methyltransferase JBrowse link 1 266,482,787 266,514,570 RGD:11554173
G Atxn7 ataxin 7 JBrowse link 15 12,421,432 12,569,649 RGD:11554173
G Ccl20 C-C motif chemokine ligand 20 JBrowse link 9 88,918,359 88,921,017 RGD:11554173
G Ccl4 C-C motif chemokine ligand 4 JBrowse link 10 70,870,926 70,886,357 RGD:11554173
G Ccrl2 C-C motif chemokine receptor like 2 JBrowse link 8 119,324,298 119,326,954 RGD:11554173
G Cd44 CD44 molecule (Indian blood group) JBrowse link 3 92,695,083 92,783,820 RGD:11554173
G Cd83 CD83 molecule JBrowse link 17 24,416,651 24,435,790 RGD:11554173
G Cdkn1a cyclin-dependent kinase inhibitor 1A JBrowse link 20 6,348,422 6,358,864 RGD:8662429
G Crp C-reactive protein JBrowse link 13 91,080,448 91,081,358 RGD:11554173
G Cxcl2 C-X-C motif chemokine ligand 2 JBrowse link 14 18,731,346 18,733,391 RGD:11554173
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit JBrowse link 1 80,256,973 80,268,198 RGD:11554173
G Ercc3 ERCC excision repair 3, TFIIH core complex helicase subunit JBrowse link 18 25,037,668 25,068,380 RGD:11554173
G Ercc4 ERCC excision repair 4, endonuclease catalytic subunit JBrowse link 10 2,010,140 2,037,953 RGD:11554173
G Gadd45b growth arrest and DNA-damage-inducible, beta JBrowse link 7 11,646,283 11,648,338 RGD:11554173
G Golga4 golgin A4 JBrowse link 8 127,171,221 127,248,938 RGD:11554173
G Gsr glutathione-disulfide reductase JBrowse link 16 62,197,617 62,239,987 RGD:10401880
G Hspa1b heat shock protein family A (Hsp70) member 1B JBrowse link 20 4,877,638 4,880,112 RGD:11554173
G Id2 inhibitor of DNA binding 2 JBrowse link 6 44,360,077 44,361,908 RGD:11554173
G Ier3 immediate early response 3 JBrowse link 20 3,438,798 3,440,002 RGD:11554173
G Il1a interleukin 1 alpha JBrowse link 3 121,824,712 121,836,122 RGD:11554173
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:11554173
G Il1rn interleukin 1 receptor antagonist JBrowse link 3 1,449,778 1,468,624 RGD:11554173
G Inpp5a inositol polyphosphate-5-phosphatase A JBrowse link 1 211,732,163 211,920,844 RGD:11554173
G Kcnj2 potassium voltage-gated channel subfamily J member 2 JBrowse link 10 99,429,337 99,442,520 RGD:11554173
G Krt10 keratin 10 JBrowse link 10 87,296,445 87,301,307 RGD:11554173
G LOC103690114 zinc finger protein 383-like JBrowse link 1 87,790,112 87,801,824 RGD:11554173
G Minpp1 multiple inositol-polyphosphate phosphatase 1 JBrowse link 1 251,045,352 251,071,045 RGD:11554173
G Mir145 microRNA 145 JBrowse link 18 56,969,907 56,969,994 RGD:11554173
G Mt1 metallothionein 1 JBrowse link 19 11,301,991 11,303,007 RGD:11554173
G Mthfr methylenetetrahydrofolate reductase JBrowse link 5 164,844,642 164,864,360 RGD:11554173
G N4bp2l2 NEDD4 binding protein 2-like 2 JBrowse link 12 627,128 650,604 RGD:11554173
G Ndufb8 NADH:ubiquinone oxidoreductase subunit B8 JBrowse link 1 264,298,671 264,303,712 RGD:11554173
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 JBrowse link 3 43,111,258 43,128,391 RGD:11554173
G Pde4b phosphodiesterase 4B JBrowse link 5 121,759,236 122,136,814 RGD:11554173
G Peli1 pellino E3 ubiquitin protein ligase 1 JBrowse link 14 106,008,086 106,062,566 RGD:11554173
G Pfkfb3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 JBrowse link 17 70,632,778 70,713,736 RGD:11554173
G Pias1 protein inhibitor of activated STAT, 1 JBrowse link 8 67,771,720 67,869,015 RGD:11554173
G Pnp purine nucleoside phosphorylase JBrowse link 15 27,875,883 27,883,566 RGD:11554173
G Ptx3 pentraxin 3 JBrowse link 2 158,097,843 158,103,653 RGD:11554173
G Rfx3 regulatory factor X3 JBrowse link 1 245,853,332 246,110,648 RGD:11554173
G Rgs1 regulator of G-protein signaling 1 JBrowse link 13 61,066,196 61,070,772 RGD:11554173
G Rnf20 ring finger protein 20 JBrowse link 5 64,892,996 64,920,397 RGD:9831407
G Rufy3 RUN and FYVE domain containing 3 JBrowse link 14 21,058,575 21,144,775 RGD:11554173
G Sfpq splicing factor proline and glutamine rich JBrowse link 5 145,079,803 145,088,517 RGD:11554173
G Skil SKI-like proto-oncogene JBrowse link 2 115,862,932 115,891,304 RGD:11554173
G Sod2 superoxide dismutase 2 JBrowse link 1 47,914,757 47,921,587 RGD:11554173
G Sox18 SRY box 18 JBrowse link 3 177,177,237 177,179,039 RGD:11554173
G Srp68 signal recognition particle 68 JBrowse link 10 105,123,324 105,150,080 RGD:11554173
G Ssbp1 single stranded DNA binding protein 1 JBrowse link 4 68,634,844 68,645,112 RGD:11554173
G Taf1d TATA-box binding protein associated factor, RNA polymerase I subunit D JBrowse link 8 13,861,242 13,871,508 RGD:11554173
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:11554173
G Tnfaip6 TNF alpha induced protein 6 JBrowse link 3 37,545,238 37,564,704 RGD:11554173
G Tnik TRAF2 and NCK interacting kinase JBrowse link 2 113,984,599 114,391,805 RGD:11554173
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:11554173
G Tra2a transformer 2 alpha homolog JBrowse link 4 78,905,380 78,924,203 RGD:11554173
G Trappc10 trafficking protein particle complex 10 JBrowse link 20 11,168,298 11,228,634 RGD:11554173
G Ube2e1 ubiquitin-conjugating enzyme E2E 1 JBrowse link 15 8,124,869 8,178,252 RGD:11554173
G Uso1 USO1 vesicle transport factor JBrowse link 14 17,371,451 17,436,948 RGD:11554173
G Usp13 ubiquitin specific peptidase 13 JBrowse link 2 119,197,153 119,317,507 RGD:11554173
G Zfand6 zinc finger AN1-type containing 6 JBrowse link 1 146,745,850 146,823,762 RGD:11554173

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 14875
    Chemically-Induced Disorders 1145
      Poisoning 665
        Arsenic Poisoning 63
Path 2
Term Annotations click to browse term
  disease 14875
    disease of anatomical entity 14051
      nervous system disease 9116
        toxic encephalopathy 156
          Heavy Metal Poisoning, Nervous System 82
            Arsenic Poisoning 63
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.