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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Dehydration
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Accession:DOID:9007993 term browser browse the term
Definition:The condition that results from excessive loss of water from a living organism.
Synonyms:exact_synonym: Water Stress
 primary_id: MESH:D003681;   RDO:0005317
For additional species annotation, visit the Alliance of Genome Resources.


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Dehydration term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Avp arginine vasopressin IEP
ISO
mRNA:increased expression:paraventricular hypothalamic nucleus, supraoptic nucleus
CTD Direct Evidence: therapeutic
CTD PMID:2554359, PMID:17393298 RGD:2304139 NCBI chr 3:123,117,482...123,119,460
Ensembl chr 3:123,117,492...123,119,460
JBrowse link
G Dmd dystrophin IEP protein:decreased expression:neurohypophysial lobe: RGD PMID:9858364 RGD:12880360 NCBI chr  X:51,149,358...53,519,271
Ensembl chr  X:51,286,737...53,519,259
JBrowse link
G Hap1 huntingtin-associated protein 1 ISO RGD PMID:11971876 RGD:1302538 NCBI chr10:88,257,975...88,266,210
Ensembl chr10:88,257,976...88,266,210
JBrowse link
G Nos1 nitric oxide synthase 1 IEP RGD PMID:16052497 RGD:13825136 NCBI chr12:44,214,949...44,405,530
Ensembl chr12:44,213,943...44,520,341
JBrowse link
G Npy1r neuropeptide Y receptor Y1 IEP protein:increased expression:hypothalamus RGD PMID:16728491 RGD:1642311 NCBI chr16:24,779,480...24,789,131
Ensembl chr16:24,779,477...24,788,740
JBrowse link
G Oxt oxytocin/neurophysin I prepropeptide IEP mRNA:increased expression:paraventricular hypothalamic nucleus, supraoptic nucleus RGD PMID:17393298 RGD:2304139 NCBI chr 3:123,106,694...123,107,534
Ensembl chr 3:123,106,694...123,107,534
JBrowse link
G P2ry2 purinergic receptor P2Y2 IEP mRNA, protein:decreased expression:inner renal medulla RGD PMID:15687250 RGD:2316687 NCBI chr 1:166,031,228...166,045,423
Ensembl chr 1:166,031,272...166,037,424
JBrowse link
G Pcsk1 proprotein convertase subtilisin/kexin type 1 IEP associated with Protein-Energy Malnutrition; protein:increased expression:pituitary (rat) RGD PMID:12411741 RGD:2308904 NCBI chr 2:91,450,162...91,497,091
Ensembl chr 2:91,450,162...91,497,091
JBrowse link
G Pcsk1n proprotein convertase subtilisin/kexin type 1 inhibitor IEP RGD PMID:17412804 RGD:1642352 NCBI chr  X:15,324,263...15,327,705 JBrowse link
G Pdia3 protein disulfide isomerase family A, member 3 IEP protein:increased expression:brain: RGD PMID:17412804 RGD:1642352 NCBI chr 3:113,376,983...113,400,707
Ensembl chr 3:113,376,983...113,400,707
JBrowse link
G Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta IEP mRNA, protein:increased expression:supraoptic nucleus, pituitary RGD PMID:17927670 RGD:9587478 NCBI chr 7:75,573,553...75,598,295
Ensembl chr 7:75,574,967...75,597,276
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 16103
    Pathological Conditions, Signs and Symptoms 8723
      Pathologic Processes 6127
        Dehydration 11
Path 2
Term Annotations click to browse term
  disease 16103
    Nutritional and Metabolic Diseases 4720
      disease of metabolism 4720
        Water-Electrolyte Imbalance 68
          Dehydration 11
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.