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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Somatosensory Disorders
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Accession:DOID:9008625 term browser browse the term
Definition:Disorders of sensory information received from superficial and deep regions of the body. The somatosensory system conveys neural impulses which pertain to proprioception, tactile sensation, thermal sensation, pressure sensation, and pain. PERIPHERAL NERVOUS SYSTEM DISEASES; SPINAL CORD DISEASES; and BRAIN DISEASES may be associated with impaired or abnormal somatic sensation.
Synonyms:exact_synonym: Light Touch Sensation Impairment;   Pain Sensation Diminished;   Pain Sensation Diminisheds;   Pinprick Sensation Diminished;   Pinprick Sensation Diminisheds;   Position Sense Disorder;   Position Sense Disorders;   Proprioceptive Disorder;   Proprioceptive Disorders;   Somatic Sensation Disorder;   Somatic Sensation Disorders;   Somatosensory Disorder;   Thermal Sensation Disorder;   Thermal Sensation Disorders
 primary_id: MESH:D020886;   RDO:0005828
For additional species annotation, visit the Alliance of Genome Resources.


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Somatosensory Disorders term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CSF3 colony stimulating factor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:7543699 NCBI chr17:17,271,074...17,273,493
Ensembl chr17:17,491,276...17,493,729
JBrowse link
G TTPA alpha tocopherol transfer protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:10896705 NCBI chr 8:59,591,592...59,619,658
Ensembl chr 8:61,266,954...61,293,699
JBrowse link
chromosome 13q14 deletion syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACOD1 aconitate decarboxylase 1 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr13:58,166,872...58,176,146
Ensembl chr13:77,211,430...77,222,201
JBrowse link
G ALG11 ALG11 alpha-1,2-mannosyltransferase ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr13:33,144,708...33,166,033
Ensembl chr13:51,888,738...51,905,894
JBrowse link
G ARL11 ADP ribosylation factor like GTPase 11 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr13:30,767,431...30,770,962
Ensembl chr13:49,518,030...49,518,620
JBrowse link
G ATP7B ATPase copper transporting beta ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr13:33,063,698...33,144,528
Ensembl chr13:51,810,555...51,851,839
JBrowse link
G BORA BORA aurora kinase A activator ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr13:53,956,913...53,985,355
Ensembl chr13:72,733,006...72,761,432
JBrowse link
G C13H13orf42 chromosome 13 C13orf42 homolog ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr13:32,216,898...32,247,120 JBrowse link
G CAB39L calcium binding protein 39 like ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr13:30,446,643...30,584,608
Ensembl chr13:49,198,143...49,288,816
JBrowse link
G CCDC70 coiled-coil domain containing 70 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr13:32,991,931...32,997,329
Ensembl chr13:51,741,930...51,742,631
JBrowse link
G CDADC1 cytidine and dCMP deaminase domain containing 1 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr13:30,386,671...30,432,112
Ensembl chr13:49,138,498...49,186,541
JBrowse link
G CKAP2 cytoskeleton associated protein 2 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr13:33,371,744...33,393,483
Ensembl chr13:52,378,278...52,399,608
JBrowse link
G CLN5 CLN5 intracellular trafficking protein ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr13:58,207,542...58,220,697
Ensembl chr13:77,253,203...77,263,759
JBrowse link
G CNMD chondromodulin ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr13:33,737,029...33,776,588
Ensembl chr13:52,547,943...52,584,720
JBrowse link
G COMMD6 COMM domain containing 6 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr13:56,752,787...56,764,664 JBrowse link
G CYSLTR2 cysteinyl leukotriene receptor 2 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr13:29,796,598...29,853,676
Ensembl chr13:48,551,757...48,552,797
JBrowse link
G DACH1 dachshund family transcription factor 1 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr13:52,666,569...53,098,257 JBrowse link
G DHRS12 dehydrogenase/reductase 12 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr13:32,897,182...32,932,715
Ensembl chr13:51,642,208...51,672,203
JBrowse link
G DIAPH3 diaphanous related formin 3 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr13:40,846,270...41,335,920
Ensembl chr13:59,676,307...60,056,672
JBrowse link
G DIS3 DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr13:53,982,914...54,011,076
Ensembl chr13:72,760,610...72,787,325
JBrowse link
G DLEU7 deleted in lymphocytic leukemia 7 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr13:31,834,182...31,982,703
Ensembl chr13:50,706,111...50,726,445
JBrowse link
G EBPL EBP like ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr13:30,799,832...30,830,670
Ensembl chr13:49,548,230...49,578,820
JBrowse link
G EDNRB endothelin receptor type B ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr13:59,112,349...59,136,615
Ensembl chr13:78,153,020...78,177,286
JBrowse link
G FAM124A family with sequence similarity 124 member A ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr13:32,356,260...32,418,132
Ensembl chr13:51,101,704...51,163,916
JBrowse link
G FBXL3 F-box and leucine rich repeat protein 3 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr13:58,219,260...58,244,780
Ensembl chr13:77,266,496...77,283,651
JBrowse link
G FNDC3A fibronectin type III domain containing 3A ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr13:30,119,740...30,347,544
Ensembl chr13:48,820,018...49,049,274
JBrowse link
G HNRNPA1L2 heterogeneous nuclear ribonucleoprotein A1 like 2 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr13:33,653,693...33,680,196
Ensembl chr13:52,487,132...52,488,093
JBrowse link
G INTS6 integrator complex subunit 6 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr13:32,487,169...32,583,415
Ensembl chr13:51,242,452...51,327,882
JBrowse link
G ITM2B integral membrane protein 2B ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr13:29,383,318...29,412,018 JBrowse link
G KCNRG potassium channel regulator ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr13:31,154,531...31,161,081
Ensembl chr13:49,901,696...49,908,169
JBrowse link
G KCTD12 potassium channel tetramerization domain containing 12 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr13:58,097,764...58,104,972 JBrowse link
G KLF12 Kruppel like factor 12 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr13:54,916,443...55,535,131
Ensembl chr13:73,697,912...73,996,956
JBrowse link
G KLF5 Kruppel like factor 5 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr13:54,287,578...54,310,216 JBrowse link
G KLHL1 kelch like family member 1 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr13:50,906,581...51,335,692
Ensembl chr13:69,691,537...70,118,448
JBrowse link
G KPNA3 karyopherin subunit alpha 3 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr13:30,838,320...30,931,608
Ensembl chr13:49,586,544...49,679,906
JBrowse link
G LMO7 LIM domain 7 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr13:56,846,724...57,084,178
Ensembl chr13:75,894,529...76,130,080
JBrowse link
G LOC100982148 LMO7 downstream neighbor protein ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr13:57,096,039...57,109,497 JBrowse link
G LOC100992351 putative UPF0607 protein ENSP00000383144 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr13:58,877,777...58,879,200 JBrowse link
G LPAR6 lysophosphatidic acid receptor 6 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr13:29,561,219...29,567,414
Ensembl chr13:48,263,254...48,264,291
JBrowse link
G MED4 mediator complex subunit 4 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr13:29,227,620...29,247,082
Ensembl chr13:47,929,918...47,948,836
JBrowse link
G MLNR motilin receptor ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr13:30,358,092...30,362,419
Ensembl chr13:49,109,918...49,111,850
JBrowse link
G MYCBP2 MYC binding protein 2 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr13:58,262,251...58,544,819
Ensembl chr13:77,306,509...77,586,843
JBrowse link
G MZT1 mitotic spindle organizing protein 1 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr13:53,937,689...53,956,954 JBrowse link
G NDFIP2 Nedd4 family interacting protein 2 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr13:60,717,590...60,792,373
Ensembl chr13:79,745,362...79,820,286
JBrowse link
G NEK3 NIMA related kinase 3 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr13:33,261,186...33,288,316
Ensembl chr13:52,003,518...52,030,212
JBrowse link
G NEK5 NIMA related kinase 5 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr13:33,166,069...33,260,990
Ensembl chr13:51,938,342...51,998,357
JBrowse link
G NUDT15 nudix hydrolase 15 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr13:29,189,459...29,198,825
Ensembl chr13:47,891,557...47,900,971
JBrowse link
G OBI1 ORC ubiquitin ligase 1 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr13:59,840,406...59,884,765
Ensembl chr13:78,874,466...78,918,446
JBrowse link
G OLFM4 olfactomedin 4 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr13:34,066,155...34,089,468
Ensembl chr13:52,873,289...52,896,827
JBrowse link
G PCDH17 protocadherin 17 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr13:38,801,514...38,900,811
Ensembl chr13:57,532,850...57,631,725
JBrowse link
G PCDH20 protocadherin 20 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr13:42,582,806...42,588,890 JBrowse link
G PCDH8 protocadherin 8 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr13:33,880,543...33,886,243
Ensembl chr13:52,688,522...52,692,399
JBrowse link
G PCDH9 protocadherin 9 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr13:47,512,960...48,430,521
Ensembl chr13:66,310,212...67,222,134
JBrowse link
G PHF11 PHD finger protein 11 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr13:30,636,035...30,670,262
Ensembl chr13:49,386,374...49,419,310
JBrowse link
G PIBF1 progesterone immunomodulatory binding factor 1 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr13:54,011,239...54,247,952
Ensembl chr13:72,788,608...73,022,473
JBrowse link
G POU4F1 POU class 4 homeobox 1 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr13:59,821,614...59,829,671 JBrowse link
G PRR20E proline rich 20E ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr13:38,340,469...38,342,105 JBrowse link
G RB1 RB transcriptional corepressor 1 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr13:29,453,872...29,624,665
Ensembl chr13:48,155,795...48,324,575
JBrowse link
G RBM26 RNA binding motif protein 26 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr13:60,547,197...60,642,551
Ensembl chr13:79,585,632...79,670,999
JBrowse link
G RCBTB1 RCC1 and BTB domain containing protein 1 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr13:30,673,230...30,727,480
Ensembl chr13:49,422,283...49,475,857
JBrowse link
G RCBTB2 RCC1 and BTB domain containing protein 2 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr13:29,631,741...29,675,959
Ensembl chr13:48,332,860...48,377,336
JBrowse link
G RNASEH2B ribonuclease H2 subunit B ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr13:32,047,830...32,108,573
Ensembl chr13:50,795,701...50,852,909
JBrowse link
G SCEL sciellin ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr13:58,772,893...58,861,813
Ensembl chr13:77,795,230...77,904,016
JBrowse link
G SERPINE3 serpin family E member 3 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr13:32,475,429...32,496,700
Ensembl chr13:51,220,735...51,241,791
JBrowse link
G SETDB2 SET domain bifurcated histone lysine methyltransferase 2 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr13:30,584,762...30,635,408
Ensembl chr13:49,335,894...49,386,150
JBrowse link
G SLAIN1 SLAIN motif family member 1 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr13:58,914,327...58,981,193 JBrowse link
G SLITRK1 SLIT and NTRK like family member 1 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr13:65,081,844...65,087,135
Ensembl chr13:84,253,287...84,256,069
JBrowse link
G SLITRK6 SLIT and NTRK like family member 6 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr13:66,990,025...67,003,900
Ensembl chr13:86,161,905...86,164,430
JBrowse link
G SPRY2 sprouty RTK signaling antagonist 2 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr13:61,569,658...61,574,817
Ensembl chr13:80,596,346...80,597,408
JBrowse link
G SPRYD7 SPRY domain containing 7 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr13:31,053,278...31,076,746
Ensembl chr13:49,801,309...49,824,463
JBrowse link
G SUCLA2 succinate-CoA ligase ADP-forming subunit beta ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr13:29,095,062...29,189,618
Ensembl chr13:47,797,472...47,856,138
JBrowse link
G SUGT1 SGT1 homolog, MIS12 kinetochore complex assembly cochaperone ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr13:33,688,941...33,724,687
Ensembl chr13:52,497,557...52,532,434
JBrowse link
G TBC1D4 TBC1 domain family member 4 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr13:56,513,065...56,706,491
Ensembl chr13:75,282,441...75,361,729
JBrowse link
G TDRD3 tudor domain containing 3 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr13:41,568,080...41,750,288
Ensembl chr13:60,290,518...60,470,245
JBrowse link
G THSD1 thrombospondin type 1 domain containing 1 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr13:33,442,480...33,472,259
Ensembl chr13:52,301,206...52,330,504
JBrowse link
G TMEM272 transmembrane protein 272 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr13:32,940,896...33,065,397 JBrowse link
G TRIM13 tripartite motif containing 13 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr13:31,137,236...31,153,398
Ensembl chr13:49,889,041...49,900,488
JBrowse link
G UCHL3 ubiquitin C-terminal hydrolase L3 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr13:56,776,436...56,832,539
Ensembl chr13:75,549,647...75,878,673
JBrowse link
G UTP14C UTP14C small subunit processome component ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr13:33,144,810...33,166,033
Ensembl chr13:51,905,055...51,908,218
JBrowse link
G VPS36 vacuolar protein sorting 36 homolog ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr13:33,398,165...33,436,615
Ensembl chr13:52,336,484...52,372,851
JBrowse link
G WDFY2 WD repeat and FYVE domain containing 2 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr13:32,714,088...32,896,885
Ensembl chr13:51,535,071...51,636,052
JBrowse link
Distal Arthrogryposis, with Impaired Proprioception and Touch term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PIEZO2 piezo type mechanosensitive ion channel component 2 ISO OMIM NCBI chr18:3,141,285...3,619,885
Ensembl chr18:5,407,467...5,882,928
JBrowse link
familial retinoblastoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RB1 RB transcriptional corepressor 1 ISO DNA:mutations:promoter, intron, exon:multiple RGD PMID:17096365 RGD:8547984 NCBI chr13:29,453,872...29,624,665
Ensembl chr13:48,155,795...48,324,575
JBrowse link
Hyperalgesia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABAT 4-aminobutyrate aminotransferase treatment ISO RGD PMID:24890317 RGD:9588557 NCBI chr16:7,609,282...7,718,049
Ensembl chr16:8,888,178...8,958,420
JBrowse link
G ADK adenosine kinase ISO associated with diabetic neuropathies; RGD PMID:9932716, PMID:11423084 RGD:6482662, RGD:6482666 NCBI chr10:70,672,967...71,236,950
Ensembl chr10:73,342,900...73,902,490
JBrowse link
G ADM adrenomedullin ISO CTD Direct Evidence: marker/mechanism RGD
CTD
PMID:17043245 RGD:1625316 NCBI chr11:10,437,712...10,440,053
Ensembl chr11:10,165,418...10,167,842
JBrowse link
G ADORA1 adenosine A1 receptor ISO associated with Spinal Cord Injuries RGD PMID:20065990 RGD:5129094 NCBI chr 1:178,728,751...178,769,066
Ensembl chr 1:183,023,466...183,063,760
JBrowse link
G ADRA1A adrenoceptor alpha 1A ISO associated with Diabetes Mellitus, Experimental; mRNA:increased expression:dorsal root ganglion RGD PMID:10841349 RGD:5688377 NCBI chr 8:25,947,996...26,138,022
Ensembl chr 8:22,853,677...23,044,388
JBrowse link
G ADRA2A adrenoceptor alpha 2A ISO RGD PMID:17959985 RGD:6480488 NCBI chr10:107,669,860...107,673,685 JBrowse link
G ADRA2C adrenoceptor alpha 2C ISO RGD PMID:20007733 RGD:6893568 NCBI chr 4:3,904,346...3,906,577 JBrowse link
G ADRB1 adrenoceptor beta 1 ISO RGD PMID:19283893 RGD:5129125 NCBI chr10:110,642,491...110,646,595 JBrowse link
G AGER advanced glycosylation end-product specific receptor treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:24077211, PMID:25014009 RGD:7364865, RGD:8695980 NCBI chr 6:31,828,363...31,831,981
Ensembl chr 6:32,708,251...32,711,641
JBrowse link
G AGT angiotensinogen ISO CTD Direct Evidence: marker/mechanism CTD PMID:9613798 NCBI chr 1:206,252,141...206,263,830
Ensembl chr 1:211,279,015...211,291,044
JBrowse link
G AIF1 allograft inflammatory factor 1 ISO associated with Alcohol-Induced Disorders, Nervous System; protein:increased expression:spinal cord (rat)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:17284346, PMID:27093858 RGD:2313035 NCBI chr 6:31,276,215...31,278,051
Ensembl chr 6:32,166,301...32,168,125
JBrowse link
G AKR1B1 aldo-keto reductase family 1 member B ISO associated with Hyperglycemia RGD PMID:12505670 RGD:1626082 NCBI chr 7:126,400,861...126,417,756
Ensembl chr 7:138,912,953...138,924,095
JBrowse link
G ALOX12 arachidonate 12-lipoxygenase, 12S type ISO CTD Direct Evidence: marker/mechanism CTD PMID:12582831 NCBI chr17:7,026,839...7,041,598
Ensembl chr17:7,014,591...7,029,602
JBrowse link
G ALOX5 arachidonate 5-lipoxygenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:12582831 NCBI chr10:42,461,398...42,531,576
Ensembl chr10:45,639,946...45,710,016
JBrowse link
G ANO3 anoctamin 3 ISO RGD PMID:23872594 RGD:9681745 NCBI chr11:26,287,123...26,618,710
Ensembl chr11:26,047,200...26,519,646
JBrowse link
G ANXA1 annexin A1 ISO protein:increased expression:dorsal root ganglion RGD PMID:9222544, PMID:21990306 RGD:2306950, RGD:7421656 NCBI chr 9:51,647,404...51,665,990
Ensembl chr 9:71,929,728...71,948,779
JBrowse link
G AQP4 aquaporin 4 ISO associated with Spinal Cord Injuries;mRNA,protein:increased expression:brain,spinal cord: RGD PMID:16219025 RGD:8695957 NCBI chr18:20,108,607...20,122,381
Ensembl chr18:23,713,146...23,726,919
JBrowse link
G AVP arginine vasopressin ISO CTD Direct Evidence: marker/mechanism CTD PMID:9613798 NCBI chr20:3,169,094...3,172,900 JBrowse link
G BACE1 beta-secretase 1 ISO RGD PMID:28012171 RGD:13782150 NCBI chr11:112,120,950...112,151,505
Ensembl chr11:116,054,303...116,084,812
JBrowse link
G BDKRB1 bradykinin receptor B1 ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:12637034, PMID:12927641, PMID:17989505, PMID:19300402, PMID:19815945 RGD:1579989, RGD:7241581 NCBI chr14:76,885,923...76,894,456 JBrowse link
G BDKRB2 bradykinin receptor B2 ISO associated with Diabetic Neuropathy
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:10188975, PMID:17989505, PMID:19300402, PMID:19815945 RGD:2313332, RGD:4891040 NCBI chr14:76,832,833...76,873,860
Ensembl chr14:96,156,494...96,196,253
JBrowse link
G BDNF brain derived neurotrophic factor ISO associated with inflammation;protein:increased expression:dorsal root ganglion:
associated with Sciatic Neuropathy;
associated with Peripheral Nerve Injuries;
associated with Pancreatitis, Chronic;
RGD PMID:10779676, PMID:11425916, PMID:12435470, PMID:12470870, PMID:21499209, PMID:21864655, PMID:21958434 RGD:8657088, RGD:8657091, RGD:8657093, RGD:8657099, RGD:8657101, RGD:8657114, RGD:8657122 NCBI chr11:27,618,322...27,687,661
Ensembl chr11:27,520,312...27,589,239
JBrowse link
G BECN1 beclin 1 ISO RGD PMID:23665054 RGD:11560531 NCBI chr17:14,493,619...14,507,809
Ensembl chr17:14,719,781...14,733,286
JBrowse link
G C3 complement C3 ISO associated with Sciatic Neuropathy;mRNA, protein:increased expression:spinal cord RGD PMID:23588254 RGD:7401259 NCBI chr19:5,708,211...5,753,178
Ensembl chr19:6,629,287...6,674,699
JBrowse link
G CACNA1B calcium voltage-gated channel subunit alpha1 B ISO RGD PMID:17567797 RGD:1626313 NCBI chr 9:108,989,621...109,256,841 JBrowse link
G CACNA1H calcium voltage-gated channel subunit alpha1 H ISO CTD Direct Evidence: marker/mechanism CTD PMID:19577366, PMID:30552955 Ensembl chr16:1,195,364...1,222,917 JBrowse link
G CACNA1I calcium voltage-gated channel subunit alpha1 I ISO RGD PMID:17112407 RGD:15003199 NCBI chr22:20,463,511...20,595,253
Ensembl chr22:38,296,436...38,414,963
JBrowse link
G CACNA2D1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11245671, PMID:17881535, PMID:24133248 NCBI chr 7:73,917,439...74,410,627
Ensembl chr 7:87,579,004...88,068,482
JBrowse link
G CALCA calcitonin related polypeptide alpha ISO CTD Direct Evidence: marker/mechanism|therapeutic
associated with inflammation;protein:increased expression:dorsal root ganglion:
CTD
RGD
PMID:12787826, PMID:12855330, PMID:15265675, PMID:21958434, PMID:27093858 RGD:8657122 NCBI chr11:15,055,897...15,061,539
Ensembl chr11:14,745,588...14,751,267
JBrowse link
G CAMK2A calcium/calmodulin dependent protein kinase II alpha ISO CTD Direct Evidence: marker/mechanism RGD
CTD
PMID:18042863, PMID:20053885 RGD:7240711 NCBI chr 5:145,644,164...145,714,143
Ensembl chr 5:151,649,062...151,719,373
JBrowse link
G CAPN2 calpain 2 treatment ISO associated with Peripheral Nerve Injuries RGD PMID:25150005 RGD:13792585 NCBI chr 1:199,335,582...199,399,267
Ensembl chr 1:204,335,573...204,409,150
JBrowse link
G CARTPT CART prepropeptide ISO CTD Direct Evidence: therapeutic CTD PMID:21167239 NCBI chr 5:43,591,683...43,593,586
Ensembl chr 5:44,236,114...44,238,229
JBrowse link
G CAT catalase treatment ISO RGD PMID:23658840, PMID:23952340 RGD:9479063, RGD:9479069 NCBI chr11:34,413,253...34,446,831
Ensembl chr11:34,289,603...34,323,160
JBrowse link
G CCK cholecystokinin ISO RGD PMID:15647484 RGD:1626108 NCBI chr 3:42,168,012...42,176,358
Ensembl chr 3:42,431,022...42,439,396
JBrowse link
G CCKBR cholecystokinin B receptor ISO CTD Direct Evidence: marker/mechanism RGD
CTD
PMID:11880531, PMID:15647484 RGD:1626108 NCBI chr11:6,393,435...6,405,821
Ensembl chr11:6,075,816...6,088,145
JBrowse link
G CCL2 C-C motif chemokine ligand 2 ISO protein:increased expression:dorsal root ganglion, spinal cord (rat)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:17881535, PMID:18419759, PMID:20737477, PMID:21712071, PMID:22531750 RGD:2307043, RGD:8548845, RGD:8548848, RGD:8548873 NCBI chr17:22,528,154...22,530,091
Ensembl chr17:22,820,890...22,823,384
JBrowse link
G CCL5 C-C motif chemokine ligand 5 ISO mRNA:increased expression:dorsal root ganglion (rat) RGD PMID:18076762, PMID:18656466 RGD:2303121, RGD:4890034 NCBI chr17:20,915,198...20,923,530
Ensembl chr17:21,210,798...21,219,172
JBrowse link
G CCR2 C-C motif chemokine receptor 2 ISO associated with Intervertebral disc disease;
associated with Demyelinating Diseases;
protein:increased expression:dorsal horn of spinal cord:
associated with Sciatic Neuropathy;
associated with Bone Neoplasms;protein:increased expression:spinal cord:
RGD PMID:18076762, PMID:18419759, PMID:22721162, PMID:23511129, PMID:24462503, PMID:24907405 RGD:2307043, RGD:4890034, RGD:8548831, RGD:8661772, RGD:8661781, RGD:8661788 NCBI chr 3:46,255,725...46,263,285
Ensembl chr 3:47,361,124...47,368,312
JBrowse link
G CCR5 C-C motif chemokine receptor 5 ISO associated with Spinal Cord Injuries
mRNA:increased expression:dorsal root ganglion (rat)
RGD PMID:18076762, PMID:22033364, PMID:23147416, PMID:24589480 RGD:4890034, RGD:8551795, RGD:8551809, RGD:8551820 NCBI chr 3:46,273,096...46,278,471
Ensembl chr 3:47,380,321...47,381,379
JBrowse link
G CFL1 cofilin 1 ISO protein:increased phosphorylation:dorsal root ganglion (rat) RGD PMID:24962708 RGD:11570412 NCBI chr11:61,215,092...61,218,628
Ensembl chr11:64,544,275...64,550,806
JBrowse link
G CNR1 cannabinoid receptor 1 ISO CTD Direct Evidence: therapeutic CTD PMID:17572696 NCBI chr 6:86,017,141...86,044,889 JBrowse link
G CNR2 cannabinoid receptor 2 ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:17572696, PMID:18664590 NCBI chr 1:23,066,153...23,108,065
Ensembl chr 1:24,050,008...24,051,090
JBrowse link
G COMT catechol-O-methyltransferase ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:20726980, PMID:28195063 RGD:8662326 NCBI chr22:2,704,015...2,731,326
Ensembl chr22:18,375,434...18,402,387
JBrowse link
G CRCP CGRP receptor component ISO RGD PMID:12895509 RGD:727768 NCBI chr 7:59,908,648...59,948,822
Ensembl chr 7:73,181,170...73,219,243
JBrowse link
G CRHR1 corticotropin releasing hormone receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28434951 NCBI chr17:11,261,435...11,313,630 JBrowse link
G CSF3 colony stimulating factor 3 treatment ISO associated with Sciatic Neuropathy; RGD PMID:24253780 RGD:11039470 NCBI chr17:17,271,074...17,273,493
Ensembl chr17:17,491,276...17,493,729
JBrowse link
G CSK C-terminal Src kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:16769263 NCBI chr15:53,724,814...53,745,710
Ensembl chr15:73,342,703...73,363,476
JBrowse link
G CTSS cathepsin S ISO associated with Colitis
associated with Arthritis, Experimental
RGD PMID:21802389, PMID:22213084 RGD:5686870, RGD:5686873 NCBI chr 1:126,084,249...126,118,221
Ensembl chr 1:129,733,996...129,768,318
JBrowse link
G CX3CL1 C-X3-C motif chemokine ligand 1 treatment ISO associated with Arthritis, Experimental RGD PMID:19249394, PMID:22647647 RGD:2304251, RGD:9491779 NCBI chr16:37,646,447...37,659,078
Ensembl chr16:56,779,065...56,791,760
JBrowse link
G CX3CR1 C-X3-C motif chemokine receptor 1 ISO associated with Arthritis, Experimental;protein:increased expression:lumbar spinal cord
associated with Inflammation
associated with Bone Neoplasms
associated with Sciatic Neuropathy
RGD PMID:16324111, PMID:19959384, PMID:20524966, PMID:20609517, PMID:20736819, PMID:22647647 RGD:4891885, RGD:4891942, RGD:4892020, RGD:9354422, RGD:9387859, RGD:9491779 NCBI chr 3:39,158,346...39,176,604
Ensembl chr 3:39,440,955...39,457,219
JBrowse link
G CXCL12 C-X-C motif chemokine ligand 12 ISO RGD PMID:28638088 RGD:13838657 NCBI chr10:41,296,975...41,384,864 JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:7881729, PMID:10401557 NCBI chr 4:50,452,857...50,456,015
Ensembl chr 4:56,286,708...56,288,083
JBrowse link
G CXCR2 C-X-C motif chemokine receptor 2 ISO RGD PMID:19283893 RGD:5129125 NCBI chr2B:105,387,198...105,400,533
Ensembl chr2B:223,997,066...223,998,148
JBrowse link
G CXCR4 C-X-C motif chemokine receptor 4 treatment ISO RGD PMID:28638088, PMID:30142543 RGD:13838657, RGD:13838658 NCBI chr2B:23,744,271...23,748,106
Ensembl chr2B:140,181,829...140,189,647
JBrowse link
G DLG4 discs large MAGUK scaffold protein 4 ISO associated with Diabetic neuropathies; RGD PMID:20531396 RGD:7257680 NCBI chr17:7,219,911...7,247,509
Ensembl chr17:7,207,483...7,235,985
JBrowse link
G DNMT1 DNA methyltransferase 1 ISO RGD PMID:21682946 RGD:9588311 NCBI chr19:9,681,847...9,745,334
Ensembl chr19:10,342,478...10,406,972
JBrowse link
G DRD3 dopamine receptor D3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20433900 NCBI chr 3:111,265,834...111,317,176
Ensembl chr 3:118,187,636...118,237,403
JBrowse link
G DUSP1 dual specificity phosphatase 1 treatment ISO associated with Sciatic Neuropathy RGD PMID:22540262, PMID:22901764 RGD:7771531, RGD:7771574 NCBI chr 5:168,121,536...168,124,671
Ensembl chr 5:175,032,803...175,035,960
JBrowse link
G DUSP6 dual specificity phosphatase 6 treatment ISO associated with Sciatic Neuropathy RGD PMID:22901764 RGD:7771531 NCBI chr12:86,875,289...86,879,731
Ensembl chr12:90,195,482...90,200,321
JBrowse link
G EDN1 endothelin 1 susceptibility ISO CTD Direct Evidence: marker/mechanism
mRNA:increased expression:paw skin (mouse)
CTD
RGD
PMID:15664691, PMID:19429182, PMID:23347081 RGD:8661716, RGD:8661735 NCBI chr 6:12,076,312...12,142,861
Ensembl chr 6:12,462,718...12,503,545
JBrowse link
G ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 treatment ISO RGD PMID:20392816 RGD:9685429 NCBI chr 8:116,248,587...116,364,966
Ensembl chr 8:118,998,530...119,114,273
JBrowse link
G EP300 E1A binding protein p300 ISO RGD PMID:25263804 RGD:9588307 NCBI chr22:21,986,467...22,076,921
Ensembl chr22:40,079,503...40,168,604
JBrowse link
G EPHA4 EPH receptor A4 ISO associated with spinal cord injuries; RGD PMID:16959251 RGD:5688783 NCBI chr2B:108,664,475...108,818,802
Ensembl chr2B:227,248,958...227,402,790
JBrowse link
G EPHX2 epoxide hydrolase 2 ISO RGD PMID:16962614 RGD:5688387 NCBI chr 8:26,761,090...26,818,436
Ensembl chr 8:23,964,094...24,017,749
JBrowse link
G ESR1 estrogen receptor 1 ISO RGD PMID:19285805 RGD:8553066 NCBI chr 6:149,507,599...149,918,523
Ensembl chr 6:154,317,002...154,631,551
JBrowse link
G ESR2 estrogen receptor 2 ISO RGD PMID:17056036, PMID:19285805 RGD:5508846, RGD:8553066 NCBI chr14:44,807,875...44,919,780
Ensembl chr14:63,064,402...63,131,303
JBrowse link
G F2 coagulation factor II, thrombin ISO associated with Sciatic Neuropathy RGD PMID:16251448 RGD:7387272 NCBI chr11:46,669,925...46,690,391
Ensembl chr11:47,227,891...47,249,157
JBrowse link
G F2R coagulation factor II thrombin receptor severity ISO RGD PMID:11877315, PMID:12717003, PMID:19674841 RGD:7387269, RGD:7387270, RGD:7387271 NCBI chr 5:38,565,957...38,585,725
Ensembl chr 5:39,110,170...39,129,688
JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:dorsal horn of spinal cord, neuron
CTD
RGD
PMID:22160634, PMID:27093858 RGD:9999169 NCBI chr14:55,832,570...55,835,984
Ensembl chr14:74,676,316...74,679,766
JBrowse link
G GAL galanin and GMAP prepropeptide ISO CTD Direct Evidence: marker/mechanism CTD PMID:12787826 NCBI chr11:63,770,758...63,777,421
Ensembl chr11:67,075,547...67,081,696
JBrowse link
G GDNF glial cell derived neurotrophic factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:20457222 NCBI chr 5:72,539,374...72,566,918
Ensembl chr 5:77,577,313...77,601,362
JBrowse link
G GFAP glial fibrillary acidic protein ISO CTD Direct Evidence: marker/mechanism
associated with Spinal Cord Injuries;mRNA,protein:increased expression:brain,spinal cord:
CTD
RGD
PMID:16219025, PMID:27093858 RGD:8695957 NCBI chr17:12,407,211...12,417,072
Ensembl chr17:12,579,754...12,591,961
JBrowse link
G GFRA1 GDNF family receptor alpha 1 ISO RGD PMID:16464682 RGD:6218969 NCBI chr10:112,645,574...112,862,413
Ensembl chr10:116,079,063...116,295,164
JBrowse link
G GJA1 gap junction protein alpha 1 treatment ISO associated with Sciatic Neuropathy RGD PMID:23374942, PMID:24631560 RGD:8662447, RGD:8662456 NCBI chr 6:119,213,513...119,227,617 JBrowse link
G GRIN1 glutamate ionotropic receptor NMDA type subunit 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27093858 NCBI chr 9:108,198,350...108,228,887
Ensembl chr 9:137,168,722...137,197,382
JBrowse link
G GRIN2A glutamate ionotropic receptor NMDA type subunit 2A ISO RGD PMID:29758384 RGD:13792698 NCBI chr16:8,682,169...9,105,581
Ensembl chr16:9,919,143...10,336,167
JBrowse link
G GRIN2B glutamate ionotropic receptor NMDA type subunit 2B treatment ISO CTD Direct Evidence: marker/mechanism RGD
CTD
PMID:20042082, PMID:24204988 RGD:13210755 NCBI chr12:13,543,104...13,987,437
Ensembl chr12:13,969,387...14,388,799
JBrowse link
G GRK2 G protein-coupled receptor kinase 2 treatment
severity
ISO associated with Complex Regional Pain Syndromes
associated with bone cancer
RGD PMID:22796071, PMID:25466829, PMID:26064176, PMID:26935064 RGD:13513996, RGD:13514046, RGD:13514049, RGD:13792780 NCBI chr11:62,624,647...62,644,846
Ensembl chr11:65,939,164...65,959,066
JBrowse link
G GRM8 glutamate metabotropic receptor 8 ISO RGD PMID:17113112 RGD:6771186 NCBI chr 7:118,430,086...119,249,147 JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha ISO associated with Limb Ischemia;protein:increased expression:foot muscle, plantar RGD PMID:18691814 RGD:9068903 NCBI chr14:42,295,691...42,348,478
Ensembl chr14:60,552,374...60,604,885
JBrowse link
G HMGB1 high mobility group box 1 treatment ISO CTD Direct Evidence: marker/mechanism RGD
CTD
PMID:24077211, PMID:27474498, PMID:30142543 RGD:13838658, RGD:7364865 NCBI chr13:11,737,942...11,894,923
Ensembl chr13:30,174,899...30,179,527
JBrowse link
G HOXD1 homeobox D1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21151121 NCBI chr2B:63,468,317...63,470,658 JBrowse link
G HTR2A 5-hydroxytryptamine receptor 2A ISO CTD Direct Evidence: marker/mechanism
associated with Diabetic neuropathies;
CTD
RGD
PMID:17888573, PMID:18930597, PMID:20531396 RGD:7257680 NCBI chr13:27,976,415...28,042,941
Ensembl chr13:46,694,273...46,759,826
JBrowse link
G HTR7 5-hydroxytryptamine receptor 7 ISO RGD PMID:21693130, PMID:21843960 RGD:6480665, RGD:6482179 NCBI chr10:87,480,970...87,598,212
Ensembl chr10:91,009,941...91,125,158
JBrowse link
G IGF1 insulin like growth factor 1 ISO CTD Direct Evidence: therapeutic CTD PMID:9452187 NCBI chr12:99,986,887...100,066,773 JBrowse link
G IL10 interleukin 10 treatment ISO associated with Sciatic Neuropathy
CTD Direct Evidence: marker/mechanism|therapeutic
RGD
CTD
PMID:7582491, PMID:17174526, PMID:22820166, PMID:23957449, PMID:24077211 RGD:7364792, RGD:7364827, RGD:7364865 NCBI chr 1:182,369,234...182,374,207
Ensembl chr 1:186,648,289...186,653,371
JBrowse link
G IL13 interleukin 13 treatment ISO RGD PMID:11399514 RGD:8549555 NCBI chr 5:128,073,863...128,078,453
Ensembl chr 5:134,235,788...134,240,548
JBrowse link
G IL17A interleukin 17A treatment ISO RGD PMID:23192794, PMID:23246025 RGD:9068942, RGD:9222699 NCBI chr 6:51,736,269...51,740,538
Ensembl chr 6:53,004,820...53,009,074
JBrowse link
G IL18 interleukin 18 treatment ISO associated with Peripheral Nerve Injuries RGD PMID:19036970 RGD:8655929 NCBI chr11:107,024,376...107,045,194
Ensembl chr11:110,867,586...110,888,371
JBrowse link
G IL1A interleukin 1 alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:12727271 NCBI chr2A:89,273,482...89,284,421
Ensembl chr2A:113,784,854...113,795,801
JBrowse link
G IL1B interleukin 1 beta ISO associated with Peripheral Nerve Injuries
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:7582491, PMID:8741165, PMID:10401557, PMID:12727271, PMID:15317861, PMID:17320857, PMID:20937348, PMID:22265659, PMID:23159984, PMID:27093858 RGD:1626676, RGD:6482671, RGD:7175548, RGD:7401209 NCBI chr2A:89,216,313...89,223,358
Ensembl chr2A:113,846,306...113,853,424
JBrowse link
G IL1R1 interleukin 1 receptor type 1 ISO RGD PMID:11585580, PMID:19022353 RGD:8662898, RGD:8662903 Ensembl chr2A:103,193,131...103,230,005 JBrowse link
G IL2 interleukin 2 treatment ISO associated with Sciatic Neuropathy; mRNA,protein:increased expression:spinal cord: RGD PMID:12755376, PMID:18423867, PMID:22189457 RGD:8662973, RGD:8662977, RGD:8662980 NCBI chr 4:114,637,328...114,642,586
Ensembl chr 4:125,782,563...125,787,984
JBrowse link
G IL33 interleukin 33 ISO RGD PMID:29329586 RGD:40400909 NCBI chr 9:6,027,014...6,069,540
Ensembl chr 9:6,234,178...6,248,624
JBrowse link
G IL6 interleukin 6 ISO associated with Foot Injuries; protein:increased expression:serum:
mRNA:increased expression:dorsal root ganglion
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:7582491, PMID:10401557, PMID:18652822, PMID:18988309, PMID:23953943 RGD:10402830, RGD:8662979 NCBI chr 7:23,415,922...23,420,767 JBrowse link
G IL6R interleukin 6 receptor ISO mRNA:increased expression:dorsal root ganglion RGD PMID:23953943 RGD:10402830 NCBI chr 1:129,761,914...129,824,386
Ensembl chr 1:133,374,078...133,433,089
JBrowse link
G INSR insulin receptor treatment ISO associated with Diabetic Neuropathies
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:18331706, PMID:23511693 RGD:10403050 NCBI chr19:6,393,407...6,578,234
Ensembl chr19:7,260,246...7,414,889
JBrowse link
G ITGA1 integrin subunit alpha 1 ISO PGE2-induced
knock-down using a specific monoclonal antibody or RNAi
RGD PMID:14984413, PMID:15836982 RGD:2302139, RGD:2302389 NCBI chr 5:61,073,507...61,247,565
Ensembl chr 5:62,692,673...62,865,769
JBrowse link
G ITGA2 integrin subunit alpha 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18234883 NCBI chr 5:60,935,452...61,040,726
Ensembl chr 5:62,555,370...62,659,720
JBrowse link
G ITGA3 integrin subunit alpha 3 ISO knock-down using a specific monoclonal antibody or RNAi RGD PMID:14984413, PMID:15836982 RGD:2302139, RGD:2302389 NCBI chr17:44,145,974...44,181,343
Ensembl chr17:49,019,892...49,055,245
JBrowse link
G ITGA5 integrin subunit alpha 5 ISO epinephrine-induced
knock-down using a specific monoclonal antibody or RNAi
RGD PMID:14984413, PMID:15836982 RGD:2302139, RGD:2302389 NCBI chr12:34,326,182...34,350,050
Ensembl chr12:35,052,994...35,075,835
JBrowse link
G ITGB1 integrin subunit beta 1 ISO knock-down using a specific monoclonal antibody or RNAi RGD PMID:14984413, PMID:15836982 RGD:2302139, RGD:2302389 NCBI chr10:33,023,573...33,081,384
Ensembl chr10:33,608,978...33,644,031
JBrowse link
G ITPR1 inositol 1,4,5-trisphosphate receptor type 1 ISO RGD PMID:25972297 RGD:13793383 NCBI chr 3:4,448,574...4,802,545
Ensembl chr 3:4,572,921...4,904,811
JBrowse link
G JAK2 Janus kinase 2 treatment ISO associated with Diabetic Neuropathies RGD PMID:18636982, PMID:23511693 RGD:10403050, RGD:6483031 NCBI chr 9:4,820,303...4,971,867
Ensembl chr 9:5,006,271...5,156,626
JBrowse link
G JAK3 Janus kinase 3 treatment ISO RGD PMID:21434883 RGD:11533942 NCBI chr19:17,299,129...17,330,700
Ensembl chr19:18,283,560...18,300,964
JBrowse link
G KCNC4 potassium voltage-gated channel subfamily C member 4 ISO RGD PMID:17855600 RGD:10411908 NCBI chr 1:112,860,887...112,884,687
Ensembl chr 1:127,458,968...127,480,182
JBrowse link
G KCNK2 potassium two pore domain channel subfamily K member 2 ISO RGD PMID:16675954 RGD:9831112 NCBI chr 1:190,576,180...190,807,367
Ensembl chr 1:195,430,994...195,662,840
JBrowse link
G KCNQ3 potassium voltage-gated channel subfamily Q member 3 ISO associated with Bone Neoplasms;protein:decreased expression:dorsal root ganglia (rat) RGD PMID:23352759 RGD:9686417 NCBI chr 8:128,769,930...129,134,671
Ensembl chr 8:131,755,454...131,815,237
JBrowse link
G KMO kynurenine 3-monooxygenase treatment ISO RGD PMID:26524415 RGD:13703043 NCBI chr 1:217,094,037...217,157,827
Ensembl chr 1:222,075,268...222,138,866
JBrowse link
G KNG1 kininogen 1 ISO CTD Direct Evidence: marker/mechanism RGD
CTD
PMID:2010815, PMID:2128375, PMID:3061568, PMID:7493622, PMID:7582491, PMID:7881729, PMID:9714424, PMID:9720808, PMID:10401557, PMID:10499367, PMID:10543429, PMID:15626726, PMID:16259764, PMID:16793879, PMID:18234883, PMID:20868656, PMID:21521205 RGD:11059894 NCBI chr 3:183,751,598...183,778,655
Ensembl chr 3:192,219,462...192,245,149
JBrowse link
G LOC100982531 cytochrome b-245 heavy chain ISO associated with Spinal Cord Injuries; RGD PMID:20679217 RGD:11040629 NCBI chr  X:30,230,394...30,267,379
Ensembl chr  X:37,939,704...37,973,183
JBrowse link
G LOC100991079 interleukin-1 receptor antagonist protein treatment
severity
ISO associated with Arthritis, Experimental; rat model treated with human protein
CTD Direct Evidence: marker/mechanism|therapeutic
RGD
CTD
PMID:8864563, PMID:10903985, PMID:15317861, PMID:17174526, PMID:17959986, PMID:20937348, PMID:22933159, PMID:23092240 RGD:6909165, RGD:6909175, RGD:7401210, RGD:8549800 NCBI chr2A:88,991,646...89,008,013
Ensembl chr2A:114,061,182...114,078,839
JBrowse link
G MAP1LC3A microtubule associated protein 1 light chain 3 alpha ISO RGD PMID:23665054 RGD:11560531 NCBI chr20:30,887,345...30,888,986
Ensembl chr20:32,010,284...32,020,411
JBrowse link
G MAPK1 mitogen-activated protein kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12941468, PMID:27093858 NCBI chr22:3,883,119...3,990,368
Ensembl chr22:20,365,487...20,450,335
JBrowse link
G MAPK3 mitogen-activated protein kinase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12941468, PMID:27093858 Ensembl chr16:30,489,362...30,498,017 JBrowse link
G MAPK7 mitogen-activated protein kinase 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17237256 NCBI chr17:31,729,429...31,736,216
Ensembl chr17:36,894,146...36,899,969
JBrowse link
G MAPK8 mitogen-activated protein kinase 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27093858 NCBI chr10:45,806,748...45,936,362 JBrowse link
G MAPK9 mitogen-activated protein kinase 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27093858 NCBI chr 5:175,437,167...175,495,469
Ensembl chr 5:182,748,381...182,795,135
JBrowse link
G MC4R melanocortin 4 receptor ISO protein:increased expression:dorsal root ganglia (rat) RGD PMID:20081244 RGD:6484233 NCBI chr18:53,744,172...53,747,282
Ensembl chr18:57,069,259...57,070,257
JBrowse link
G MEN1 menin 1 ISO associated with Sciatic Neuropathy;protein:increased expression:spinal cord dorsal horn (rat) RGD PMID:20369282 RGD:9589142 NCBI chr11:60,159,009...60,166,222
Ensembl chr11:63,499,962...63,507,164
JBrowse link
G MFN2 mitofusin 2 ISO CTD Direct Evidence: marker/mechanism
mRNA:decreased expression:spinal cord (rat)
CTD
RGD
PMID:28587902 RGD:12910704 NCBI chr 1:10,729,933...10,764,865
Ensembl chr 1:11,945,880...11,981,077
JBrowse link
G MMP3 matrix metallopeptidase 3 ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:18754875, PMID:22056600 RGD:8693664 NCBI chr11:97,776,729...97,784,549
Ensembl chr11:101,267,566...101,275,354
JBrowse link
G MPZ myelin protein zero ISO CTD Direct Evidence: marker/mechanism CTD PMID:16676325 NCBI chr 1:136,691,245...136,720,958
Ensembl chr 1:140,626,039...140,631,273
JBrowse link
G MTOR mechanistic target of rapamycin kinase ISO RGD PMID:24382350 RGD:10040983 NCBI chr 1:9,871,700...10,028,704
Ensembl chr 1:11,093,765...11,249,841
JBrowse link
G NEFH neurofilament heavy treatment ISO RGD PMID:21071147 RGD:27226885 NCBI chr22:10,525,738...10,536,788 JBrowse link
G NGF nerve growth factor treatment ISO associated with Cystitis
associated with Peripheral Nerve Injuries;
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:11425916, PMID:16203088, PMID:18448607, PMID:20457222, PMID:22839415 RGD:7242799, RGD:7242803, RGD:7242849, RGD:8657088 NCBI chr 1:87,223,597...87,276,759 JBrowse link
G NGFR nerve growth factor receptor treatment ISO associated with Brachial Plexus Neuropathies RGD PMID:23324933 RGD:10413898 NCBI chr17:8,089,600...8,109,361
Ensembl chr17:8,075,316...8,094,966
JBrowse link
G NLGN2 neuroligin 2 ISO RGD PMID:23891900 RGD:9831150 NCBI chr17:7,438,853...7,454,014 JBrowse link
G NOS1 nitric oxide synthase 1 ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:19300402, PMID:23909597 RGD:7257597 NCBI chr12:114,784,232...114,938,385
Ensembl chr12:118,163,655...118,314,005
JBrowse link
G NOS2 nitric oxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17989504, PMID:19300402 NCBI chr17:28,984,295...29,021,516
Ensembl chr17:29,471,510...29,617,093
JBrowse link
G NPY neuropeptide Y treatment ISO associated with Sciatic Neuropathy RGD PMID:19556004 RGD:10448929 NCBI chr 7:24,963,056...24,970,803
Ensembl chr 7:24,568,041...24,574,657
JBrowse link
G NRG1 neuregulin 1 ISO associated with Sciatic Neuropathy RGD PMID:22212401 RGD:10449019 NCBI chr 8:30,954,852...32,084,411
Ensembl chr 8:29,050,222...29,263,977
JBrowse link
G NTF3 neurotrophin 3 ISO CTD Direct Evidence: therapeutic CTD PMID:15659614 NCBI chr12:5,551,734...5,615,981
Ensembl chr12:5,530,508...5,533,989
JBrowse link
G NTRK2 neurotrophic receptor tyrosine kinase 2 ISO associated with inflammation;protein:increased expression:dorsal root ganglion: RGD PMID:12470870, PMID:21958434 RGD:8657091, RGD:8657122 NCBI chr 9:39,663,986...40,208,770
Ensembl chr 9:84,021,837...84,372,678
JBrowse link
G NTSR1 neurotensin receptor 1 ISO RGD PMID:22396077 RGD:9743902 NCBI chr20:59,100,110...59,151,563
Ensembl chr20:60,392,736...60,446,056
JBrowse link
G OPRK1 opioid receptor kappa 1 treatment ISO associated with Diabetes Mellitus, Experimental; RGD PMID:16924480 RGD:9834947 NCBI chr 8:49,650,844...49,677,494
Ensembl chr 8:47,029,313...47,056,577
JBrowse link
G OPRL1 opioid related nociceptin receptor 1 ISO associated with Sciatic Neuropathy;mRNA:increased expression:spinal cord lumbar segment,dorsal root ganglion: RGD PMID:12106803 RGD:9835017 Ensembl chr20:62,004,176...62,017,866 JBrowse link
G OPRM1 opioid receptor mu 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17996026 NCBI chr 6:151,827,323...151,937,658
Ensembl chr 6:156,517,661...157,088,251
JBrowse link
G P2RX2 purinergic receptor P2X 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19383439 NCBI chr12:129,969,793...129,974,399 JBrowse link
G P2RX3 purinergic receptor P2X 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19383439 NCBI chr11:52,579,190...52,614,329
Ensembl chr 3:160,070,875...160,106,120
JBrowse link
G P2RY12 purinergic receptor P2Y12 ISO RGD PMID:20136836, PMID:20398327 RGD:6480525, RGD:6480526 NCBI chr 3:148,364,151...148,412,231 JBrowse link
G PAWR pro-apoptotic WT1 regulator treatment ISO RGD PMID:17179954 RGD:9835416 NCBI chr12:77,114,282...77,224,116
Ensembl chr12:79,969,517...80,070,796
JBrowse link
G PDYN prodynorphin ISO CTD Direct Evidence: marker/mechanism CTD PMID:17670969 NCBI chr20:2,092,171...2,108,141
Ensembl chr20:1,856,850...1,872,452
JBrowse link
G PENK proenkephalin treatment ISO associated with Diabetes Mellitus, Experimental; RGD PMID:23235561 RGD:10003116 NCBI chr 8:52,864,388...52,870,144
Ensembl chr 8:50,234,170...50,239,949
JBrowse link
G PLA2G4A phospholipase A2 group IVA ISO RGD PMID:16203828 RGD:1642461 NCBI chr 1:162,362,600...162,521,974
Ensembl chr 1:166,512,870...166,672,101
JBrowse link
G PNOC prepronociceptin ISO CTD Direct Evidence: marker/mechanism CTD PMID:12665541, PMID:19231294 NCBI chr 8:27,596,413...27,622,844
Ensembl chr 8:24,796,638...24,822,758
JBrowse link
G PPP2CA protein phosphatase 2 catalytic subunit alpha ISO RGD PMID:26732138 RGD:11572421 NCBI chr 5:129,599,606...129,629,312
Ensembl chr 5:135,751,958...135,765,786
JBrowse link
G PRKCB protein kinase C beta ISO associated with inflammation;protein:increased activity:spinal cord RGD PMID:16360284 RGD:1625519 NCBI chr16:13,888,936...14,268,759
Ensembl chr16:24,091,289...24,466,203
JBrowse link
G PRKCE protein kinase C epsilon ISO CTD Direct Evidence: marker/mechanism CTD PMID:11738263, PMID:12582831, PMID:20457222 NCBI chr2A:45,757,629...46,294,064
Ensembl chr2A:46,688,436...47,220,313
JBrowse link
G PRKCG protein kinase C gamma treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:12560106, PMID:19955894, PMID:27093858 RGD:28867224 NCBI chr19:50,823,372...50,849,003
Ensembl chr19:59,672,097...59,695,977
JBrowse link
G PRKCZ protein kinase C zeta ISO CTD Direct Evidence: marker/mechanism CTD PMID:27899695 NCBI chr 1:763,942...901,531
Ensembl chr 1:1,920,219...2,045,855
JBrowse link
G PRKG1 protein kinase cGMP-dependent 1 treatment ISO RGD PMID:14973199 RGD:7775058 NCBI chr10:47,642,312...48,935,188
Ensembl chr10:49,779,211...51,064,882
JBrowse link
G PROK2 prokineticin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16793879 NCBI chr 3:71,711,334...71,724,865
Ensembl chr 3:73,068,599...73,080,897
JBrowse link
G PROKR1 prokineticin receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16793879 NCBI chr2A:68,685,129...68,700,372
Ensembl chr2A:69,808,033...69,822,404
JBrowse link
G PTAFR platelet activating factor receptor treatment ISO RGD PMID:16925995 RGD:10041052 NCBI chr 1:27,405,880...27,436,184
Ensembl chr 1:28,447,833...28,448,861
JBrowse link
G PTGER1 prostaglandin E receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11375261 NCBI chr19:14,035,876...14,038,812 JBrowse link
G PTGER3 prostaglandin E receptor 3 ISO protein:increased expression:lumbar spinal cord dorsal horn (rat) RGD PMID:17413918 RGD:5688169 NCBI chr 1:70,076,610...70,271,475
Ensembl chr 1:72,059,441...72,254,063
JBrowse link
G PTGER4 prostaglandin E receptor 4 treatment ISO RGD PMID:20423341 RGD:10003041 NCBI chr 5:69,686,906...69,700,739
Ensembl chr 5:74,731,470...74,745,148
JBrowse link
G PTGES3 prostaglandin E synthase 3 ISO RGD PMID:16192391 RGD:5688057 NCBI chr12:32,221,908...32,247,228
Ensembl chr12:32,476,835...32,503,181
JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 ISO protein:increased expression:spinal cord
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:17413918, PMID:17989504 RGD:5688169 NCBI chr 9:93,495,365...93,517,557
Ensembl chr 9:121,837,095...121,859,283
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:15464832, PMID:17112505, PMID:17989504 RGD:5688224 NCBI chr 1:162,205,534...162,214,130
Ensembl chr 1:166,355,845...166,364,519
JBrowse link
G PTHLH parathyroid hormone like hormone ISO CTD Direct Evidence: marker/mechanism CTD PMID:16769263 NCBI chr12:58,341,361...58,355,804
Ensembl chr12:60,960,071...60,973,750
JBrowse link
G RAF1 Raf-1 proto-oncogene, serine/threonine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:18976650 NCBI chr 3:12,510,084...12,590,598
Ensembl chr 3:12,853,415...12,932,871
JBrowse link
G RGS4 regulator of G protein signaling 4 treatment ISO associated with lesion of sciatic nerve RGD PMID:27641322 RGD:13524513 NCBI chr 1:138,488,317...138,496,497
Ensembl chr 1:142,284,040...142,292,225
JBrowse link
G SCN10A sodium voltage-gated channel alpha subunit 10 ISO CTD Direct Evidence: marker/mechanism RGD
CTD
PMID:16545521, PMID:19070548 RGD:6484253 NCBI chr 3:38,593,765...38,691,172
Ensembl chr 3:38,876,068...38,972,247
JBrowse link
G SCN11A sodium voltage-gated channel alpha subunit 11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23264124 NCBI chr 3:38,741,485...38,948,400
Ensembl chr 3:39,024,921...39,128,015
JBrowse link
G SIN3A SIN3 transcription regulator family member A ISO associated with Arthritis, Experimental;mRNA:decreased expression:spinal cord, neuron RGD PMID:17553988 RGD:9495916 NCBI chr15:54,285,587...54,371,376
Ensembl chr15:73,881,500...73,966,506
JBrowse link
G SLC12A5 solute carrier family 12 member 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20086212 NCBI chr20:42,359,005...42,397,412
Ensembl chr20:43,445,182...43,483,132
JBrowse link
G SLC17A8 solute carrier family 17 member 8 ISO protein:increased expression:dorsal horn of spinal cord, neuron RGD PMID:22160634 RGD:9999169 NCBI chr12:97,935,177...98,001,240
Ensembl chr12:101,342,113...101,405,844
JBrowse link
G SPARC secreted protein acidic and cysteine rich ISO CTD Direct Evidence: marker/mechanism CTD PMID:20714283 NCBI chr 5:147,087,903...147,112,466
Ensembl chr 5:153,090,181...153,115,750
JBrowse link
G STAT3 signal transducer and activator of transcription 3 treatment ISO RGD PMID:24098399 RGD:8694290 NCBI chr17:14,928,689...15,003,644
Ensembl chr17:15,152,358...15,227,067
JBrowse link
G SYN2 synapsin II ISO CTD Direct Evidence: marker/mechanism CTD PMID:18701217 NCBI chr 3:11,935,680...12,118,981
Ensembl chr 3:12,282,573...12,464,413
JBrowse link
G TAC1 tachykinin precursor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:8864563, PMID:9714424, PMID:10499367, PMID:12351280, PMID:12787826, PMID:15626726, PMID:16259764, PMID:18234883, PMID:19231294 NCBI chr 7:89,675,834...89,684,391
Ensembl chr 7:103,257,501...103,266,389
JBrowse link
G TACR1 tachykinin receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15964684, PMID:17123731 NCBI chr2A:75,111,339...75,267,320
Ensembl chr2A:76,614,478...76,771,018
JBrowse link
G TGFBR1 transforming growth factor beta receptor 1 ISO associated with Experimental Pancreatitis, Chronic RGD PMID:26645248 RGD:14995470 NCBI chr 9:70,195,007...70,243,514
Ensembl chr 9:98,332,739...98,362,748
JBrowse link
G THBD thrombomodulin treatment ISO associated with Inflammation
CTD Direct Evidence: therapeutic
RGD
CTD
PMID:24004409, PMID:27474498 RGD:11038687 NCBI chr20:22,992,341...22,996,415
Ensembl chr20:23,345,917...23,347,812
JBrowse link
G TLR2 toll like receptor 2 ISO RGD PMID:17355971, PMID:24204973 RGD:8553059, RGD:8553185 NCBI chr 4:146,024,653...146,091,388
Ensembl chr 4:157,866,977...157,869,331
JBrowse link
G TLR4 toll like receptor 4 ISO RGD PMID:15809417, PMID:20714435, PMID:24204973 RGD:4144070, RGD:7815040, RGD:8553185 NCBI chr 9:88,827,495...88,840,458
Ensembl chr 9:117,180,550...117,190,711
JBrowse link
G TNF tumor necrosis factor ISO mRNA,protein:increased expression:spinal cord:
associated with Diabetic Neuropathies;
CTD Direct Evidence: marker/mechanism
protein:increased expression:lumbar vertebra:
RGD
CTD
PMID:7582491, PMID:7881729, PMID:10401557, PMID:10825476, PMID:12727271, PMID:16472913, PMID:16675114, PMID:17304130, PMID:17320857, PMID:17459378, PMID:18463260, PMID:18582539, PMID:18790011, PMID:20383154, PMID:21104419, PMID:26141506, PMID:27093858 RGD:7387300, RGD:7387302, RGD:7394737, RGD:7394741, RGD:7394757, RGD:7401179 NCBI chr 6:31,236,650...31,239,423
Ensembl chr 6:32,126,618...32,129,381
JBrowse link
G TNFRSF11B TNF receptor superfamily member 11b ISO CTD Direct Evidence: therapeutic CTD PMID:16769263 NCBI chr 8:115,614,778...115,643,387
Ensembl chr 8:118,134,305...118,162,422
JBrowse link
G TNFRSF1A TNF receptor superfamily member 1A treatment ISO associated with Sciatic Neuropathy RGD PMID:12752784, PMID:20417692, PMID:21145890, PMID:21712071, PMID:22652595, PMID:24257399 RGD:5130913, RGD:5130939, RGD:8548873, RGD:8661726, RGD:8661737, RGD:8661750 NCBI chr12:6,457,617...6,470,969
Ensembl chr12:6,374,257...6,387,613
JBrowse link
G TNFRSF1B TNF receptor superfamily member 1B ISO associated with Sciatic Neuropathy RGD PMID:18463260, PMID:22652595 RGD:5130960, RGD:8661750 NCBI chr 1:10,915,743...10,957,765
Ensembl chr 1:12,130,663...12,172,646
JBrowse link
G TRPA1 transient receptor potential cation channel subfamily A member 1 ISO CTD Direct Evidence: marker/mechanism
associated with Peripheral Nerve Injuries;
CTD
RGD
PMID:18234885, PMID:18954467, PMID:21481532, PMID:23523557 RGD:10043618 NCBI chr 8:68,551,685...68,605,336
Ensembl chr 8:70,210,352...70,262,627
JBrowse link
G TRPC1 transient receptor potential cation channel subfamily C member 1 ISO associated with Inflammation RGD PMID:19439599 RGD:7247605 NCBI chr 3:139,757,408...139,841,006
Ensembl chr 3:147,349,056...147,432,332
JBrowse link
G TRPC6 transient receptor potential cation channel subfamily C member 6 ISO RGD PMID:19439599 RGD:7247605 NCBI chr11:96,414,498...96,551,670
Ensembl chr11:99,919,410...100,050,685
JBrowse link
G TRPV1 transient receptor potential cation channel subfamily V member 1 ISO CTD Direct Evidence: marker/mechanism
associated with inflammation;protein:increased expression:dorsal root ganglion:
CTD
RGD
PMID:12151517, PMID:18234885, PMID:18774343, PMID:21958434, PMID:23006841 RGD:8657122 NCBI chr17:3,612,781...3,658,608
Ensembl chr17:3,609,952...3,637,579
JBrowse link
G TRPV4 transient receptor potential cation channel subfamily V member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18234883 NCBI chr12:107,359,005...107,409,359
Ensembl chr12:110,754,238...110,786,182
JBrowse link
G VIP vasoactive intestinal peptide ISO CTD Direct Evidence: marker/mechanism CTD PMID:12787826 NCBI chr 6:150,564,545...150,573,582
Ensembl chr 6:155,254,652...155,263,730
JBrowse link
Hyperesthesia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KNG1 kininogen 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:8190269 NCBI chr 3:183,751,598...183,778,655
Ensembl chr 3:192,219,462...192,245,149
JBrowse link
Hypesthesia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DARS2 aspartyl-tRNA synthetase 2, mitochondrial ISO ClinVar Annotator: match by term: Hypoesthesia ClinVar PMID:17384640, PMID:19592391, PMID:22843165, PMID:23065766, PMID:23652419, PMID:24005482, PMID:24407472, PMID:25741868, PMID:30311386 NCBI chr 1:149,342,301...149,375,979
Ensembl chr 1:153,045,886...153,080,461
JBrowse link
G DMD dystrophin ISO ClinVar Annotator: match by term: Hypoesthesia ClinVar PMID:23352160, PMID:23871722, PMID:26467025, PMID:26743743, PMID:26990548, PMID:28492532, PMID:30311386, PMID:30415094 NCBI chr  X:23,728,650...26,338,849
Ensembl chr  X:31,282,415...33,492,733
JBrowse link
G FIG4 FIG4 phosphoinositide 5-phosphatase ISO ClinVar Annotator: match by term: Hypoesthesia ClinVar PMID:26467025, PMID:28492532, PMID:29650794, PMID:30311386 NCBI chr 6:107,495,637...107,631,201
Ensembl chr 6:111,539,937...111,673,894
JBrowse link
G GJB1 gap junction protein beta 1 ISO ClinVar Annotator: match by term: Hypoesthesia ClinVar PMID:25741868, PMID:30311386 NCBI chr  X:60,490,579...60,492,606
Ensembl chr  X:70,547,110...70,547,961
JBrowse link
Hypoalgesia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AQP4 aquaporin 4 ISO RGD PMID:20851747 RGD:8696005 NCBI chr18:20,108,607...20,122,381
Ensembl chr18:23,713,146...23,726,919
JBrowse link
G HDAC4 histone deacetylase 4 ISO RGD PMID:19672313 RGD:9681457 NCBI chr2B:126,287,745...126,649,815
Ensembl chr2B:245,123,061...245,427,054
JBrowse link
ocular melanoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GNA11 G protein subunit alpha 11 ISO ClinVar Annotator: match by term: Intraocular melanoma ClinVar PMID:1328859, PMID:2549426, PMID:21083380, PMID:21444680, PMID:22733540, PMID:22808163, PMID:24141786, PMID:25157968, PMID:26619011 NCBI chr19:2,120,398...2,149,161
Ensembl chr19:3,074,483...3,102,124
JBrowse link
G GNAQ G protein subunit alpha q ISO ClinVar Annotator: match by term: Intraocular melanoma ClinVar PMID:1328859, PMID:2549426, PMID:18719078, PMID:19078957, PMID:21083380, PMID:22253748, PMID:22653968, PMID:22733540, PMID:22808163, PMID:25157968 NCBI chr 9:46,816,409...47,129,116
Ensembl chr 9:76,575,815...76,773,849
JBrowse link
Paresthesia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FKRP fukutin related protein ISO ClinVar Annotator: match by term: Paresthesias ClinVar PMID:11741828, PMID:12666124, PMID:14647208, PMID:15060126, PMID:15574464, PMID:15580560, PMID:15833432, PMID:15886712, PMID:16634037, PMID:16786213, PMID:17554798, PMID:18060779, PMID:18593008, PMID:18639457, PMID:19820980, PMID:19835634, PMID:19900540, PMID:21220724, PMID:21228398, PMID:22264518, PMID:22981120, PMID:23576288, PMID:23591631, PMID:24033266, PMID:24447024, PMID:25048216, PMID:25560911, PMID:25741868, PMID:26363967, PMID:26467025, PMID:26574668, PMID:26833294, PMID:28492532, PMID:30311386 NCBI chr19:43,738,339...43,748,250
Ensembl chr19:52,273,546...52,276,341
JBrowse link
G INS insulin ISO CTD Direct Evidence: marker/mechanism CTD PMID:9861226 NCBI chr11:2,200,785...2,202,579
Ensembl chr11:2,218,117...2,231,666
JBrowse link
G LOC100984344 calpain-3 ISO ClinVar Annotator: match by term: Paresthesias ClinVar PMID:7720071, PMID:9266733, PMID:10330340, PMID:10679950, PMID:14578192, PMID:14981715, PMID:15351423, PMID:15689361, PMID:15725583, PMID:16100770, PMID:16141003, PMID:16650086, PMID:17318636, PMID:20635405, PMID:21204801, PMID:21984748, PMID:25741868, PMID:26467025, PMID:27142102, PMID:28492532, PMID:30311386 NCBI chr15:21,227,371...21,372,406
Ensembl chr15:39,476,302...39,528,820
JBrowse link
G PMP22 peripheral myelin protein 22 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12427913 NCBI chr17:36,389,549...36,425,161
Ensembl chr17:41,038,302...41,073,872
JBrowse link
retinoblastoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALK ALK receptor tyrosine kinase ISO ClinVar Annotator: match by term: Retinoblastoma ClinVar PMID:25741868, PMID:28492532 NCBI chr2A:29,196,195...29,930,062
Ensembl chr2A:29,276,041...30,006,735
JBrowse link
G APC APC regulator of WNT signaling pathway ISO ClinVar Annotator: match by term: Retinoblastoma ClinVar PMID:25186627, PMID:25741868, PMID:28492532 NCBI chr 5:108,070,697...108,208,273
Ensembl chr 5:113,904,352...114,009,709
JBrowse link
G BRCA2 BRCA2 DNA repair associated ISO ClinVar Annotator: match by term: Retinoblastoma ClinVar PMID:17899372, PMID:19043619, PMID:20507642, PMID:22632462, PMID:25741868, PMID:25782689, PMID:28492532, PMID:29394989, PMID:29884841, PMID:30254663 NCBI chr13:13,574,422...13,658,967
Ensembl chr13:32,010,066...32,091,332
JBrowse link
G CADM2 cell adhesion molecule 2 ISO mRNA, protein:decreased expression:retina RGD PMID:30320366 RGD:15092072 NCBI chr 3:85,076,738...86,200,515
Ensembl chr 3:87,200,482...88,310,438
JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A ISO ClinVar Annotator: match by term: Retinoblastoma ClinVar PMID:25741868 NCBI chr 9:21,803,862...21,831,322 JBrowse link
G FANCM FA complementation group M ISO ClinVar Annotator: match by term: Retinoblastoma ClinVar PMID:25741868 NCBI chr14:25,752,295...25,817,001
Ensembl chr14:44,080,146...44,143,958
JBrowse link
G FAS Fas cell surface death receptor severity ISO protein:decreased expression:tumor (human) RGD PMID:14533029 RGD:8662811 NCBI chr10:85,707,457...85,741,539
Ensembl chr10:89,217,949...89,243,612
JBrowse link
G ITM2B integral membrane protein 2B ISO ClinVar Annotator: match by term: Retinoblastoma ClinVar PMID:8099255, PMID:12541220, PMID:28492532, PMID:28575107, PMID:29568217 NCBI chr13:29,383,318...29,412,018 JBrowse link
G KDM1B lysine demethylase 1B ISO mRNA:increased expression:retina (human) RGD PMID:16180235 RGD:9588276 NCBI chr 6:18,002,763...18,071,598 JBrowse link
G LPAR6 lysophosphatidic acid receptor 6 ISO ClinVar Annotator: match by term: Retinoblastoma ClinVar PMID:8099255, PMID:12541220, PMID:21505449, PMID:22909775, PMID:23301675, PMID:28492532, PMID:28575107, PMID:29568217 NCBI chr13:29,561,219...29,567,414
Ensembl chr13:48,263,254...48,264,291
JBrowse link
G MAX MYC associated factor X ISO ClinVar Annotator: match by term: Retinoblastoma ClinVar PMID:25741868, PMID:28492532 NCBI chr14:45,588,366...45,683,828
Ensembl chr14:64,535,120...64,562,671
JBrowse link
G MED4 mediator complex subunit 4 ISO ClinVar Annotator: match by term: Retinoblastoma ClinVar PMID:8099255, PMID:12541220, PMID:28492532, PMID:28575107, PMID:29568217 NCBI chr13:29,227,620...29,247,082
Ensembl chr13:47,929,918...47,948,836
JBrowse link
G MGMT O-6-methylguanine-DNA methyltransferase disease_progression ISO DNA:hypermethylation:promoter (human) RGD PMID:15799820 RGD:2317684 NCBI chr10:126,059,701...126,365,850
Ensembl chr10:130,305,485...130,609,422
JBrowse link
G MTR 5-methyltetrahydrofolate-homocysteine methyltransferase susceptibility ISO DNA:SNP::2756A>G(human) RGD PMID:20310006 RGD:8694083 NCBI chr 1:212,353,195...212,463,304
Ensembl chr 1:217,358,050...217,460,946
JBrowse link
G MUTYH mutY DNA glycosylase ISO ClinVar Annotator: match by term: Retinoblastoma ClinVar PMID:25741868, PMID:26947005, PMID:28135145, PMID:28492532 NCBI chr 1:44,632,102...44,643,292 JBrowse link
G NF1 neurofibromin 1 ISO ClinVar Annotator: match by term: Retinoblastoma ClinVar PMID:25741868, PMID:28492532 NCBI chr17:25,425,081...25,703,689
Ensembl chr17:26,160,855...26,439,295
JBrowse link
G NUDT15 nudix hydrolase 15 ISO ClinVar Annotator: match by term: Retinoblastoma ClinVar PMID:8099255, PMID:12541220, PMID:28492532, PMID:28575107, PMID:29568217 NCBI chr13:29,189,459...29,198,825
Ensembl chr13:47,891,557...47,900,971
JBrowse link
G PALB2 partner and localizer of BRCA2 ISO ClinVar Annotator: match by term: Retinoblastoma ClinVar PMID:23555315, PMID:25741868, PMID:28492532 NCBI chr16:14,470,367...14,507,841
Ensembl chr16:23,855,535...23,892,117
JBrowse link
G PTCH1 patched 1 ISO ClinVar Annotator: match by term: Retinoblastoma ClinVar PMID:24728327, PMID:25741868, PMID:28492532 NCBI chr 9:66,542,675...66,616,820
Ensembl chr 9:94,668,365...94,741,453
JBrowse link
G RB1 RB transcriptional corepressor 1 ISO OMIM NCBI chr13:29,453,872...29,624,665
Ensembl chr13:48,155,795...48,324,575
JBrowse link
G SERPINF1 serpin family F member 1 treatment ISO human protein and tumor xenograft in a mouse model RGD PMID:19832843 RGD:8554870 NCBI chr17:1,745,597...1,761,399
Ensembl chr17:1,638,556...1,653,568
JBrowse link
G SNCG synuclein gamma ISO RGD PMID:18728752 RGD:6218971 NCBI chr10:83,383,566...83,391,064 JBrowse link
G STK11 serine/threonine kinase 11 ISO ClinVar Annotator: match by term: Retinoblastoma ClinVar PMID:25741868, PMID:28135145, PMID:28492532 Ensembl chr19:1,188,537...1,210,677 JBrowse link
G TSC2 TSC complex subunit 2 ISO ClinVar Annotator: match by term: Retinoblastoma ClinVar PMID:22703879, PMID:25741868, PMID:28492532 NCBI chr16:615,776...655,411
Ensembl chr16:2,135,696...2,175,569
JBrowse link
trilateral retinoblastoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RB1 RB transcriptional corepressor 1 ISO ClinVar Annotator: match by term: Retinoblastoma, trilateral ClinVar PMID:7704558, PMID:8346255, PMID:8605116, PMID:9400934, PMID:16463005, PMID:22963398, PMID:24688104, PMID:25157968, PMID:25602518, PMID:25741868, PMID:28492532 NCBI chr13:29,453,872...29,624,665
Ensembl chr13:48,155,795...48,324,575
JBrowse link
uveal melanoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAP1 BRCA1 associated protein 1 disease_progression ISO CTD Direct Evidence: marker/mechanism
mRNA,protein:decreased expression: :
CTD
RGD
PMID:21874000, PMID:25147369, PMID:25231345, PMID:26719535 RGD:9586037 NCBI chr 3:52,344,067...52,352,187
Ensembl chr 3:53,573,785...53,581,943
JBrowse link
G BRCA2 BRCA2 DNA repair associated susceptibility ISO DNA:mutations: : RGD PMID:22187320 RGD:9068467 NCBI chr13:13,574,422...13,658,967
Ensembl chr13:32,010,066...32,091,332
JBrowse link
G CRP C-reactive protein disease_progression ISO RGD PMID:23057648 RGD:9491834 NCBI chr 1:135,062,102...135,064,402 JBrowse link
G CYSLTR2 cysteinyl leukotriene receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27089179 NCBI chr13:29,796,598...29,853,676
Ensembl chr13:48,551,757...48,552,797
JBrowse link
G EIF1AX eukaryotic translation initiation factor 1A X-linked ISO CTD Direct Evidence: marker/mechanism CTD PMID:23793026 NCBI chr  X:12,743,907...12,764,313
Ensembl chr  X:20,103,872...20,123,464
JBrowse link
G GNA11 G protein subunit alpha 11 ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Melanoma of the Uvea
CTD
ClinVar
PMID:1328859, PMID:2549426, PMID:21083380, PMID:21444680, PMID:22733540, PMID:22808163, PMID:24141786, PMID:25157968, PMID:26397223, PMID:26619011, PMID:27089179 NCBI chr19:2,120,398...2,149,161
Ensembl chr19:3,074,483...3,102,124
JBrowse link
G GNAQ G protein subunit alpha q ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Melanoma of the Uvea
CTD
ClinVar
PMID:1328859, PMID:2549426, PMID:18719078, PMID:19078957, PMID:21083380, PMID:22253748, PMID:22653968, PMID:22733540, PMID:22808163, PMID:25157968, PMID:26397223, PMID:27089179 NCBI chr 9:46,816,409...47,129,116
Ensembl chr 9:76,575,815...76,773,849
JBrowse link
G IGF1 insulin like growth factor 1 disease_progression ISO RGD PMID:23197685 RGD:8548834 NCBI chr12:99,986,887...100,066,773 JBrowse link
G JMJD6 jumonji domain containing 6, arginine demethylase and lysine hydroxylase ISO CTD Direct Evidence: marker/mechanism CTD PMID:30619488 NCBI chr17:70,789,922...70,803,791
Ensembl chr17:76,356,142...76,370,117
JBrowse link
G KDM5B lysine demethylase 5B severity ISO protein:increased expression:uvea (human) RGD PMID:22669717 RGD:9587775 NCBI chr 1:178,323,073...178,406,608
Ensembl chr 1:182,622,425...182,702,994
JBrowse link
G KDR kinase insert domain receptor disease_progression ISO RGD PMID:21984395 RGD:8549718 NCBI chr 4:68,813,894...68,861,018
Ensembl chr 4:75,377,375...75,427,109
JBrowse link
G LOC100982859 patr class I histocompatibility antigen, B-2 alpha chain severity ISO protein:increased expression:tumor of uvea (human) RGD PMID:9286277 RGD:7364941 NCBI chr 6:31,106,562...31,109,933
Ensembl chr 6:31,997,381...32,000,067
JBrowse link
G MCAM melanoma cell adhesion molecule disease_progression ISO RGD PMID:19958117 RGD:7364775 NCBI chr11:114,149,583...114,158,234
Ensembl chr11:118,078,179...118,083,893
JBrowse link
G PLCB4 phospholipase C beta 4 ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Uveal melanoma
CTD
ClinVar
PMID:27089179, PMID:31186267 NCBI chr20:9,042,127...9,454,207
Ensembl chr20:9,192,061...9,456,443
JBrowse link
G SERPINE1 serpin family E member 1 treatment ISO human gene in mouse model RGD PMID:9326241 RGD:8547806 NCBI chr 7:93,267,517...93,279,728
Ensembl chr 7:106,510,130...106,518,450
JBrowse link
G SERPINF1 serpin family F member 1 severity ISO RGD PMID:23793989 RGD:8554893 NCBI chr17:1,745,597...1,761,399
Ensembl chr17:1,638,556...1,653,568
JBrowse link
G SF3B1 splicing factor 3b subunit 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23313955, PMID:23793026 NCBI chr2B:84,633,272...84,678,602
Ensembl chr2B:202,530,200...202,573,346
JBrowse link
G TMEM127 transmembrane protein 127 ISO ClinVar Annotator: match by term: Uveal melanoma ClinVar PMID:25741868, PMID:28492532 NCBI chr2A:103,049,655...103,065,116
Ensembl chr2A:97,174,322...97,189,171
JBrowse link
G VEGFA vascular endothelial growth factor A ISO protein:increased expression:iris, ciliary body, vitreous body; RGD PMID:11914216 RGD:7483591 NCBI chr 6:43,361,053...43,377,366
Ensembl chr 6:44,650,365...44,666,353
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 12770
    Pathological Conditions, Signs and Symptoms 7583
      Signs and Symptoms 4649
        Neurologic Manifestations 4032
          Sensation Disorders 957
            Somatosensory Disorders 312
              Benign Cerebellar Ataxia with Thermoanalgesia 0
              Distal Arthrogryposis, with Impaired Proprioception and Touch 1
              Hyperalgesia 188
              Hyperesthesia 1
              Hypesthesia + 4
              Hypoalgesia 2
              Paresthesia 4
              sensory system cancer + 114
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.