Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Somatosensory Disorders
go back to main search page
Accession:DOID:9008625 term browser browse the term
Definition:Disorders of sensory information received from superficial and deep regions of the body. The somatosensory system conveys neural impulses which pertain to proprioception, tactile sensation, thermal sensation, pressure sensation, and pain. PERIPHERAL NERVOUS SYSTEM DISEASES; SPINAL CORD DISEASES; and BRAIN DISEASES may be associated with impaired or abnormal somatic sensation.
Synonyms:exact_synonym: Light Touch Sensation Impairment;   Pain Sensation Diminished;   Pain Sensation Diminisheds;   Pinprick Sensation Diminished;   Pinprick Sensation Diminisheds;   Position Sense Disorder;   Position Sense Disorders;   Proprioceptive Disorder;   Proprioceptive Disorders;   Somatic Sensation Disorder;   Somatic Sensation Disorders;   Somatosensory Disorder;   Thermal Sensation Disorder;   Thermal Sensation Disorders
 primary_id: MESH:D020886;   RDO:0005828
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants           Sort by:
 
Somatosensory Disorders term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CSF3 colony stimulating factor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:7543699 NCBI chr12:22,333,445...22,335,949
Ensembl chr12:22,333,445...22,342,163
JBrowse link
G TTPA alpha tocopherol transfer protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:10896705 NCBI chr 4:70,960,580...70,980,883
Ensembl chr 4:70,961,465...71,021,839
JBrowse link
chromosome 13q14 deletion syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACOD1 aconitate decarboxylase 1 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr11:49,077,152...49,088,218
Ensembl chr11:49,077,492...49,088,345
JBrowse link
G ALG11 ALG11 alpha-1,2-mannosyltransferase ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr11:15,851,352...15,876,452
Ensembl chr11:15,851,711...15,876,392
JBrowse link
G ARL11 ADP ribosylation factor like GTPase 11 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr11:18,097,723...18,100,425
Ensembl chr11:18,067,499...18,100,413
JBrowse link
G ATP7B ATPase copper transporting beta ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr11:15,892,549...15,942,070 JBrowse link
G BORA BORA aurora kinase A activator ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr11:45,017,651...45,045,127
Ensembl chr11:45,018,352...45,045,127
JBrowse link
G CAB39L calcium binding protein 39 like ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr11:18,297,669...18,400,398
Ensembl chr11:18,298,018...18,400,398
JBrowse link
G CCDC70 coiled-coil domain containing 70 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr11:15,976,814...15,978,050
Ensembl chr11:15,977,286...15,977,945
JBrowse link
G CDADC1 cytidine and dCMP deaminase domain containing 1 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr11:18,467,508...18,518,137
Ensembl chr11:18,458,299...18,518,146
JBrowse link
G CKAP2 cytoskeleton associated protein 2 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr11:15,751,717...15,767,068
Ensembl chr11:15,751,801...15,766,497
JBrowse link
G CLN5 CLN5 intracellular trafficking protein ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr11:49,105,822...49,128,425 JBrowse link
G CNMD chondromodulin ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr11:25,959,192...25,994,773
Ensembl chr11:25,961,915...25,994,651
JBrowse link
G COMMD6 COMM domain containing 6 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr11:47,795,110...47,818,543
Ensembl chr11:47,543,814...47,818,561
JBrowse link
G CYSLTR2 cysteinyl leukotriene receptor 2 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr11:18,988,665...19,011,015
Ensembl chr11:18,987,174...19,011,015
JBrowse link
G DACH1 dachshund family transcription factor 1 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr11:43,765,386...44,187,766
Ensembl chr11:43,764,270...44,188,352
JBrowse link
G DIAPH3 diaphanous related formin 3 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr11:32,492,735...32,994,854
Ensembl chr11:32,492,740...32,994,837
JBrowse link
G DIS3 DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr11:45,046,040...45,075,973
Ensembl chr11:45,044,508...45,075,910
JBrowse link
G DLEU7 deleted in lymphocytic leukemia 7 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr11:16,970,802...16,990,609
Ensembl chr11:16,972,554...16,989,394
JBrowse link
G EBPL EBP like ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr11:18,039,978...18,150,729
Ensembl chr11:18,040,010...18,087,644
JBrowse link
G EDNRB endothelin receptor type B ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr11:50,073,300...50,102,879
Ensembl chr11:50,072,554...50,102,884
JBrowse link
G FAM124A family with sequence similarity 124 member A ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr11:16,572,298...16,658,094
Ensembl chr11:16,572,295...16,658,162
JBrowse link
G FBXL3 F-box and leucine rich repeat protein 3 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr11:49,131,663...49,151,380
Ensembl chr11:49,130,182...49,151,009
JBrowse link
G FNDC3A fibronectin type III domain containing 3A ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr11:18,564,280...18,757,742
Ensembl chr11:18,564,280...18,757,869
JBrowse link
G INTS6 integrator complex subunit 6 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr11:16,373,376...16,468,246
Ensembl chr11:16,372,805...16,468,252
JBrowse link
G ITM2B integral membrane protein 2B ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr11:19,349,088...19,377,931
Ensembl chr11:19,349,133...19,377,917
JBrowse link
G KCNRG potassium channel regulator ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr11:17,784,243...17,796,826
Ensembl chr11:17,784,996...17,793,804
JBrowse link
G KCTD12 potassium channel tetramerization domain containing 12 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr11:49,025,134...49,033,208
Ensembl chr11:48,943,477...49,031,093
JBrowse link
G KLF12 Kruppel like factor 12 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr11:45,981,096...46,655,472
Ensembl chr11:45,985,542...46,459,791
JBrowse link
G KLF5 Kruppel like factor 5 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr11:45,370,009...45,386,673
Ensembl chr11:45,369,797...45,388,314
JBrowse link
G KLHL1 kelch like family member 1 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr11:42,033,842...42,420,931
Ensembl chr11:42,033,842...42,419,770
JBrowse link
G KPNA3 karyopherin subunit alpha 3 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr11:17,948,210...18,033,818
Ensembl chr11:17,947,850...18,033,787
JBrowse link
G LMO7 LIM domain 7 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr11:47,911,076...48,133,449
Ensembl chr11:47,911,096...48,133,446
JBrowse link
G LOC100155738 protocadherin-8 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr11:26,127,398...26,133,481
Ensembl chr11:26,127,399...26,132,123
JBrowse link
G LOC106505279 uncharacterized LOC106505279 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr11:16,021,127...16,034,650
Ensembl chr11:16,008,665...16,034,395
JBrowse link
G LPAR6 lysophosphatidic acid receptor 6 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr11:19,216,305...19,220,913 JBrowse link
G MED4 mediator complex subunit 4 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr11:19,551,858...19,566,915
Ensembl chr11:19,551,863...19,566,926
JBrowse link
G MIR15A microRNA mir-15a ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr11:17,757,463...17,757,541
Ensembl chr11:17,757,460...17,757,554
JBrowse link
G MIR16-2 microRNA mir-16-2 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr11:17,757,606...17,757,684
Ensembl chr11:17,757,601...17,757,687
JBrowse link
G MLNR motilin receptor ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr11:18,541,958...18,544,111
Ensembl chr11:18,542,028...18,544,025
JBrowse link
G MYCBP2 MYC binding protein 2 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr11:49,163,969...49,432,865
Ensembl chr11:49,164,141...49,432,858
JBrowse link
G MZT1 mitotic spindle organizing protein 1 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr11:45,000,735...45,019,009
Ensembl chr11:44,999,320...45,018,862
JBrowse link
G NDFIP2 Nedd4 family interacting protein 2 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr11:51,493,981...51,560,305
Ensembl chr11:51,420,166...51,560,305
JBrowse link
G NEK3 NIMA related kinase 3 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr11:15,772,578...15,798,424
Ensembl chr11:15,772,844...15,798,420
JBrowse link
G NEK5 NIMA related kinase 5 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr11:15,799,068...15,862,236
Ensembl chr11:15,801,354...15,862,231
JBrowse link
G NUDT15 nudix hydrolase 15 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr11:19,572,963...19,584,565
Ensembl chr11:19,572,644...19,584,538
JBrowse link
G OBI1 ORC ubiquitin ligase 1 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr11:50,741,893...50,786,824
Ensembl chr11:50,740,916...50,786,774
JBrowse link
G OLFM4 olfactomedin 4 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr11:26,252,948...26,375,531
Ensembl chr11:26,350,203...26,375,716
JBrowse link
G PCDH17 protocadherin 17 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr11:30,510,779...30,611,732
Ensembl chr11:30,511,261...30,611,727
JBrowse link
G PCDH20 protocadherin 20 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr11:34,384,507...34,390,265 JBrowse link
G PCDH9 protocadherin 9 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr11:38,522,221...39,455,166
Ensembl chr11:38,524,034...39,454,240
JBrowse link
G PHF11 PHD finger protein 11 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr11:18,205,073...18,252,082
Ensembl chr11:18,205,072...18,251,949
JBrowse link
G PIBF1 progesterone immunomodulatory binding factor 1 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr11:45,076,046...45,362,708
Ensembl chr11:45,076,061...45,362,891
JBrowse link
G POU4F1 POU class 4 homeobox 1 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr11:50,729,746...50,732,626
Ensembl chr11:50,730,428...50,732,340
JBrowse link
G RB1 RB transcriptional corepressor 1 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr11:19,186,754...19,317,642
Ensembl chr11:19,186,759...19,317,690
JBrowse link
G RBM26 RNA binding motif protein 26 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr11:51,337,388...51,421,746
Ensembl chr11:51,337,488...51,420,865
JBrowse link
G RCBTB1 RCC1 and BTB domain containing protein 1 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr11:18,132,013...18,197,759
Ensembl chr11:18,040,110...18,197,751
JBrowse link
G RCBTB2 RCC1 and BTB domain containing protein 2 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr11:19,081,841...19,182,488
Ensembl chr11:19,105,305...19,182,488
JBrowse link
G RNASEH2B ribonuclease H2 subunit B ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr11:16,825,799...16,911,959
Ensembl chr11:16,829,801...16,911,879
JBrowse link
G SCEL sciellin ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr11:49,651,589...49,777,777
Ensembl chr11:49,651,673...49,775,448
JBrowse link
G SERPINE3 serpin family E member 3 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr11:16,465,521...16,500,580
Ensembl chr11:16,466,475...16,500,558
JBrowse link
G SETDB2 SET domain bifurcated histone lysine methyltransferase 2 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr11:18,252,525...18,298,234
Ensembl chr11:18,252,527...18,297,826
JBrowse link
G SLAIN1 SLAIN motif family member 1 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr11:49,807,976...49,886,829
Ensembl chr11:49,807,994...49,886,820
JBrowse link
G SLITRK1 SLIT and NTRK like family member 1 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr11:54,950,669...54,955,768
Ensembl chr11:54,950,673...54,955,949
JBrowse link
G SLITRK6 SLIT and NTRK like family member 6 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr11:56,508,713...56,522,270
Ensembl chr11:56,508,709...56,522,212
JBrowse link
G SPRY2 sprouty RTK signaling antagonist 2 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr11:52,153,695...52,158,766
Ensembl chr11:52,153,704...52,160,497
JBrowse link
G SPRYD7 SPRY domain containing 7 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr11:17,849,011...17,870,090
Ensembl chr11:17,848,852...17,872,257
JBrowse link
G SUCLA2 succinate-CoA ligase ADP-forming subunit beta ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr11:19,616,415...19,670,667
Ensembl chr11:19,616,499...19,675,791
JBrowse link
G SUGT1 SGT1 homolog, MIS12 kinetochore complex assembly cochaperone ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr11:25,905,442...25,960,665
Ensembl chr11:25,906,010...25,954,210
JBrowse link
G TBC1D4 TBC1 domain family member 4 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr11:47,543,808...47,760,928
Ensembl chr11:47,543,814...47,818,561
JBrowse link
G TDRD3 tudor domain containing 3 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr11:33,257,556...33,440,131
Ensembl chr11:33,258,063...33,440,127
JBrowse link
G THSD1 thrombospondin type 1 domain containing 1 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr11:15,668,435...15,698,031
Ensembl chr11:15,667,640...15,697,872
JBrowse link
G TRIM13 tripartite motif containing 13 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr11:17,785,031...17,850,005
Ensembl chr11:17,792,467...17,849,732
JBrowse link
G UCHL3 ubiquitin C-terminal hydrolase L3 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr11:47,829,037...47,885,800
Ensembl chr11:47,829,103...47,887,629
JBrowse link
G VPS36 vacuolar protein sorting 36 homolog ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr11:15,701,370...15,735,469
Ensembl chr11:15,701,370...15,772,693
JBrowse link
G WDFY2 WD repeat and FYVE domain containing 2 ISO ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome ClinVar NCBI chr11:16,086,872...16,272,513
Ensembl chr11:16,078,058...16,301,828
JBrowse link
Distal Arthrogryposis, with Impaired Proprioception and Touch term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PIEZO2 piezo type mechanosensitive ion channel component 2 ISO OMIM NCBI chr 6:97,644,115...97,945,693
Ensembl chr 6:97,643,366...97,944,418
JBrowse link
familial retinoblastoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RB1 RB transcriptional corepressor 1 ISO DNA:mutations:promoter, intron, exon:multiple RGD PMID:17096365 RGD:8547984 NCBI chr11:19,186,754...19,317,642
Ensembl chr11:19,186,759...19,317,690
JBrowse link
Hyperalgesia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABAT 4-aminobutyrate aminotransferase treatment ISO RGD PMID:24890317 RGD:9588557 NCBI chr 3:33,913,068...33,960,804
Ensembl chr 3:33,908,965...34,015,469
JBrowse link
G ADK adenosine kinase ISO associated with diabetic neuropathies; RGD PMID:9932716, PMID:11423084 RGD:6482662, RGD:6482666 NCBI chr14:76,836,072...77,320,586
Ensembl chr14:76,836,095...77,322,416
JBrowse link
G ADM adrenomedullin ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:17043245 RGD:1625316 NCBI chr 2:49,229,223...49,231,521
Ensembl chr 2:49,229,223...49,231,866
JBrowse link
G ADORA1 adenosine A1 receptor ISO associated with Spinal Cord Injuries RGD PMID:20065990 RGD:5129094 NCBI chr 9:113,835,279...113,875,899
Ensembl chr 9:113,835,920...113,875,719
JBrowse link
G ADRA1A adrenoceptor alpha 1A ISO associated with Diabetes Mellitus, Experimental; mRNA:increased expression:dorsal root ganglion RGD PMID:10841349 RGD:5688377 NCBI chr14:10,623,391...10,733,378
Ensembl chr14:10,626,293...10,733,069
JBrowse link
G ADRA2A adrenoceptor alpha 2A ISO RGD PMID:17959985 RGD:6480488 NCBI chr14:121,469,572...121,470,924
Ensembl chr14:121,469,527...121,470,924
JBrowse link
G ADRA2C adrenoceptor alpha 2C ISO RGD PMID:20007733 RGD:6893568 NCBI chr 8:2,320,125...2,322,162
Ensembl chr 8:2,320,226...2,321,608
JBrowse link
G ADRB1 adrenoceptor beta 1 ISO RGD PMID:19283893 RGD:5129125 NCBI chr14:124,400,330...124,401,739
Ensembl chr14:124,400,189...124,401,739
JBrowse link
G AGER advanced glycosylation end-product specific receptor treatment ISO CTD Direct Evidence: marker/mechanism RGD
CTD
PMID:24077211, PMID:25014009 RGD:7364865, RGD:8695980 NCBI chr 7:24,218,116...24,221,162
Ensembl chr 7:24,218,116...24,228,756
JBrowse link
G AGT angiotensinogen ISO CTD Direct Evidence: marker/mechanism CTD PMID:9613798 NCBI chr14:59,643,030...59,656,835
Ensembl chr14:59,643,292...59,672,428
JBrowse link
G AIF1 allograft inflammatory factor 1 ISO CTD Direct Evidence: marker/mechanism
associated with Alcohol-Induced Disorders, Nervous System; protein:increased expression:spinal cord (rat)
CTD
RGD
PMID:17284346, PMID:27093858 RGD:2313035 NCBI chr 7:23,711,752...23,731,191
Ensembl chr 7:23,711,722...23,731,671
JBrowse link
G AKR1B1 aldo-keto reductase family 1 member B ISO associated with Hyperglycemia RGD PMID:12505670 RGD:1626082 NCBI chr18:14,593,516...14,752,316
Ensembl chr18:14,593,548...14,752,310
JBrowse link
G ALOX12 arachidonate 12-lipoxygenase, 12S type ISO CTD Direct Evidence: marker/mechanism CTD PMID:12582831 NCBI chr12:52,401,861...52,414,913
Ensembl chr12:52,286,019...52,414,907
JBrowse link
G ALOX5 arachidonate 5-lipoxygenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:12582831 NCBI chr14:90,859,209...90,907,084
Ensembl chr14:90,858,975...90,907,094
JBrowse link
G ANO3 anoctamin 3 ISO RGD PMID:23872594 RGD:9681745 NCBI chr 2:33,618,740...34,048,973
Ensembl chr 2:33,617,991...33,987,210
JBrowse link
G ANXA1 annexin A1 ISO protein:increased expression:dorsal root ganglion RGD PMID:9222544, PMID:21990306 RGD:2306950, RGD:7421656 NCBI chr 1:226,414,200...226,431,963
Ensembl chr 1:226,414,307...226,432,287
JBrowse link
G AQP4 aquaporin 4 ISO associated with Spinal Cord Injuries;mRNA,protein:increased expression:brain,spinal cord: RGD PMID:16219025 RGD:8695957 NCBI chr 6:111,407,632...111,422,169
Ensembl chr 6:111,400,794...111,422,042
JBrowse link
G AVP arginine vasopressin ISO CTD Direct Evidence: marker/mechanism CTD PMID:9613798 NCBI chr17:32,581,234...32,583,145
Ensembl chr17:32,581,230...32,583,427
JBrowse link
G BACE1 beta-secretase 1 ISO RGD PMID:28012171 RGD:13782150 NCBI chr 9:44,640,389...44,665,863
Ensembl chr 9:44,640,392...44,665,835
JBrowse link
G BDKRB1 bradykinin receptor B1 ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:12637034, PMID:12927641, PMID:17989505, PMID:19300402, PMID:19815945 RGD:1579989, RGD:7241581 NCBI chr 7:117,491,350...117,492,410
Ensembl chr 7:117,491,350...117,492,410
JBrowse link
G BDKRB2 bradykinin receptor B2 ISO CTD Direct Evidence: marker/mechanism
associated with Diabetic Neuropathy
CTD
RGD
PMID:10188975, PMID:17989505, PMID:19300402, PMID:19815945 RGD:2313332, RGD:4891040 NCBI chr 7:117,438,622...117,472,005
Ensembl chr 7:117,438,543...117,472,003
JBrowse link
G BDNF brain derived neurotrophic factor ISO associated with Peripheral Nerve Injuries;
associated with Sciatic Neuropathy;
associated with Pancreatitis, Chronic;
associated with inflammation;protein:increased expression:dorsal root ganglion:
RGD PMID:10779676, PMID:11425916, PMID:12435470, PMID:12470870, PMID:21499209, PMID:21864655, PMID:21958434 RGD:8657088, RGD:8657091, RGD:8657093, RGD:8657099, RGD:8657101, RGD:8657114, RGD:8657122 NCBI chr 2:32,623,668...32,679,293
Ensembl chr 2:32,623,268...32,679,164
JBrowse link
G BECN1 beclin 1 ISO RGD PMID:23665054 RGD:11560531 NCBI chr12:20,041,914...20,054,249
Ensembl chr12:20,041,956...20,054,373
JBrowse link
G C3 complement C3 ISO associated with Sciatic Neuropathy;mRNA, protein:increased expression:spinal cord RGD PMID:23588254 RGD:7401259 NCBI chr 2:72,431,470...72,471,622
Ensembl chr 2:72,431,499...72,528,112
JBrowse link
G CACNA1B calcium voltage-gated channel subunit alpha1 B ISO RGD PMID:17567797 RGD:1626313
G CACNA1H calcium voltage-gated channel subunit alpha1 H ISO CTD Direct Evidence: marker/mechanism CTD PMID:19577366, PMID:30552955 NCBI chr 3:40,637,420...40,694,616
Ensembl chr 3:40,637,436...40,694,818
JBrowse link
G CACNA1I calcium voltage-gated channel subunit alpha1 I ISO RGD PMID:17112407 RGD:15003199 NCBI chr 5:8,593,014...8,702,734
Ensembl chr 5:8,595,142...8,712,393
JBrowse link
G CACNA2D1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11245671, PMID:17881535, PMID:24133248 NCBI chr 9:97,781,057...98,265,925
Ensembl chr 9:97,780,742...98,266,573
JBrowse link
G CALCB calcitonin-related polypeptide beta ISO associated with inflammation;protein:increased expression:dorsal root ganglion:
CTD Direct Evidence: marker/mechanism|therapeutic
RGD
CTD
PMID:12787826, PMID:12855330, PMID:15265675, PMID:21958434, PMID:27093858 RGD:8657122 NCBI chr 2:44,043,135...44,048,651 JBrowse link
G CAMK2A calcium/calmodulin dependent protein kinase II alpha ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:18042863, PMID:20053885 RGD:7240711 NCBI chr 2:151,248,356...151,353,907
Ensembl chr 2:151,248,356...151,308,658
JBrowse link
G CAPN2 calpain 2 treatment ISO associated with Peripheral Nerve Injuries RGD PMID:25150005 RGD:13792585 NCBI chr10:19,758,824...19,820,241
Ensembl chr10:19,758,762...19,851,989
JBrowse link
G CARTPT CART prepropeptide ISO CTD Direct Evidence: therapeutic CTD PMID:21167239 NCBI chr16:48,043,558...48,045,592
Ensembl chr16:48,043,407...48,045,590
JBrowse link
G CAT catalase treatment ISO RGD PMID:23658840, PMID:23952340 RGD:9479063, RGD:9479069 NCBI chr 2:26,493,664...26,533,881
Ensembl chr 2:26,487,653...26,581,452
JBrowse link
G CCK cholecystokinin ISO RGD PMID:15647484 RGD:1626108 NCBI chr13:25,940,674...25,945,879
Ensembl chr13:25,937,645...25,946,197
JBrowse link
G CCKBR cholecystokinin B receptor ISO CTD Direct Evidence: marker/mechanism RGD
CTD
PMID:11880531, PMID:15647484 RGD:1626108 NCBI chr 9:3,409,222...3,419,513 JBrowse link
G CCL2 chemokine (C-C motif) ligand 2 ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:dorsal root ganglion, spinal cord (rat)
RGD
CTD
PMID:17881535, PMID:18419759, PMID:20737477, PMID:21712071, PMID:22531750 RGD:2307043, RGD:8548845, RGD:8548848, RGD:8548873 NCBI chr12:40,798,109...40,800,013
Ensembl chr12:40,798,109...40,800,028
JBrowse link
G CCL5 C-C motif chemokine ligand 5 ISO mRNA:increased expression:dorsal root ganglion (rat) RGD PMID:18076762, PMID:18656466 RGD:2303121, RGD:4890034 NCBI chr12:39,652,731...39,659,121
Ensembl chr12:39,648,598...39,659,118
JBrowse link
G CCR2 C-C motif chemokine receptor 2 ISO associated with Sciatic Neuropathy;
associated with Bone Neoplasms;protein:increased expression:spinal cord:
associated with Demyelinating Diseases;
protein:increased expression:dorsal horn of spinal cord:
associated with Intervertebral disc disease;
RGD PMID:18076762, PMID:18419759, PMID:22721162, PMID:23511129, PMID:24462503, PMID:24907405 RGD:2307043, RGD:4890034, RGD:8548831, RGD:8661772, RGD:8661781, RGD:8661788 NCBI chr13:29,368,735...29,374,564
Ensembl chr13:29,251,959...29,376,346
JBrowse link
G CCR5 chemokine (C-C motif) receptor 5 ISO associated with Spinal Cord Injuries
mRNA:increased expression:dorsal root ganglion (rat)
RGD PMID:18076762, PMID:22033364, PMID:23147416, PMID:24589480 RGD:4890034, RGD:8551795, RGD:8551809, RGD:8551820 NCBI chr13:29,382,383...29,387,902
Ensembl chr13:29,383,303...29,387,902
JBrowse link
G CFL1 cofilin 1 ISO protein:increased phosphorylation:dorsal root ganglion (rat) RGD PMID:24962708 RGD:11570412 NCBI chr 2:6,471,558...6,475,019
Ensembl chr 2:6,469,254...6,475,035
JBrowse link
G CNR1 cannabinoid receptor 1 ISO CTD Direct Evidence: therapeutic CTD PMID:17572696 NCBI chr 1:56,466,022...56,493,275
Ensembl chr 1:56,466,027...56,492,602
JBrowse link
G CNR2 cannabinoid receptor 2 ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:17572696, PMID:18664590 NCBI chr 6:81,659,162...81,692,550
Ensembl chr 6:81,659,165...81,692,550
JBrowse link
G COMT catechol-O-methyltransferase ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:20726980, PMID:28195063 RGD:8662326 NCBI chr14:51,384,729...51,403,997
Ensembl chr14:51,385,133...51,403,998
JBrowse link
G CRCP CGRP receptor component ISO RGD PMID:12895509 RGD:727768 NCBI chr 3:16,528,949...16,622,005
Ensembl chr 3:16,485,569...16,621,894
JBrowse link
G CRHR1 corticotropin releasing hormone receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28434951 NCBI chr12:17,251,361...17,306,308 JBrowse link
G CSF3 colony stimulating factor 3 treatment ISO associated with Sciatic Neuropathy; RGD PMID:24253780 RGD:11039470 NCBI chr12:22,333,445...22,335,949
Ensembl chr12:22,333,445...22,342,163
JBrowse link
G CSK C-terminal Src kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:16769263 NCBI chr 7:58,736,473...58,755,034
Ensembl chr 7:58,736,529...58,755,260
JBrowse link
G CTSS cathepsin S ISO associated with Arthritis, Experimental
associated with Colitis
RGD PMID:21802389, PMID:22213084 RGD:5686870, RGD:5686873 NCBI chr 4:98,415,273...98,442,952
Ensembl chr 4:98,390,250...98,442,936
JBrowse link
G CX3CL1 C-X3-C motif chemokine ligand 1 treatment ISO associated with Arthritis, Experimental RGD PMID:19249394, PMID:22647647 RGD:2304251, RGD:9491779 NCBI chr 6:19,312,351...19,324,439 JBrowse link
G CX3CR1 C-X3-C motif chemokine receptor 1 ISO associated with Arthritis, Experimental;protein:increased expression:lumbar spinal cord
associated with Inflammation
associated with Bone Neoplasms
associated with Sciatic Neuropathy
RGD PMID:16324111, PMID:19959384, PMID:20524966, PMID:20609517, PMID:20736819, PMID:22647647 RGD:4891885, RGD:4891942, RGD:4892020, RGD:9354422, RGD:9387859, RGD:9491779 NCBI chr13:23,944,386...23,957,567
Ensembl chr13:23,944,369...23,957,486
JBrowse link
G CXCL12 C-X-C motif chemokine ligand 12 ISO RGD PMID:28638088 RGD:13838657 NCBI chr14:91,516,383...91,543,857
Ensembl chr14:91,516,429...91,552,766
JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:7881729, PMID:10401557 NCBI chr 8:69,932,646...69,935,861
Ensembl chr 8:69,932,643...69,935,861
JBrowse link
G CXCR2 C-X-C motif chemokine receptor 2 ISO RGD PMID:19283893 RGD:5129125 NCBI chr15:120,219,657...120,230,203 JBrowse link
G CXCR4 C-X-C motif chemokine receptor 4 treatment ISO RGD PMID:28638088, PMID:30142543 RGD:13838657, RGD:13838658 NCBI chr15:15,663,652...15,666,706
Ensembl chr15:15,663,494...15,667,233
JBrowse link
G DLG4 discs large MAGUK scaffold protein 4 ISO associated with Diabetic neuropathies; RGD PMID:20531396 RGD:7257680 NCBI chr12:52,550,138...52,574,021
Ensembl chr12:52,550,141...52,575,156
JBrowse link
G DNMT1 DNA methyltransferase 1 ISO RGD PMID:21682946 RGD:9588311 NCBI chr 2:68,981,564...69,040,364
Ensembl chr 2:68,981,564...69,029,919
JBrowse link
G DRD3 dopamine receptor D3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20433900 NCBI chr13:145,769,294...145,817,997
Ensembl chr13:145,771,510...145,819,173
JBrowse link
G DUSP1 dual specificity phosphatase 1 treatment ISO associated with Sciatic Neuropathy RGD PMID:22540262, PMID:22901764 RGD:7771531, RGD:7771574 NCBI chr16:51,457,924...51,461,095
Ensembl chr16:51,458,020...51,461,086
JBrowse link
G DUSP6 dual specificity phosphatase 6 treatment ISO associated with Sciatic Neuropathy RGD PMID:22901764 RGD:7771531 NCBI chr 5:93,303,058...93,307,510
Ensembl chr 5:93,302,975...93,307,504
JBrowse link
G EDN1 endothelin 1 susceptibility ISO CTD Direct Evidence: marker/mechanism
mRNA:increased expression:paw skin (mouse)
RGD
CTD
PMID:15664691, PMID:19429182, PMID:23347081 RGD:8661716, RGD:8661735 NCBI chr 7:8,752,018...8,758,354
Ensembl chr 7:8,751,695...8,758,348
JBrowse link
G ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 treatment ISO RGD PMID:20392816 RGD:9685429 NCBI chr 4:19,319,815...19,433,492
Ensembl chr 4:19,180,234...19,433,492
JBrowse link
G EP300 E1A binding protein p300 ISO RGD PMID:25263804 RGD:9588307 NCBI chr 5:7,311,165...7,394,515
Ensembl chr 5:7,311,171...7,393,760
JBrowse link
G EPHA4 EPH receptor A4 ISO associated with spinal cord injuries; RGD PMID:16959251 RGD:5688783 NCBI chr15:123,350,867...123,501,872
Ensembl chr15:123,352,813...123,503,126
JBrowse link
G EPHX2 epoxide hydrolase 2 ISO RGD PMID:16962614 RGD:5688387 NCBI chr14:11,217,125...11,293,018
Ensembl chr14:11,216,977...11,293,412
JBrowse link
G ESR1 estrogen receptor 1 ISO RGD PMID:19285805 RGD:8553066 NCBI chr 1:14,217,032...14,604,906
Ensembl chr 1:14,217,036...14,493,363
JBrowse link
G ESR2 estrogen receptor 2 ISO RGD PMID:17056036, PMID:19285805 RGD:5508846, RGD:8553066 NCBI chr 1:193,823,666...193,907,330
Ensembl chr 1:193,722,164...193,906,565
JBrowse link
G F2 coagulation factor II, thrombin ISO associated with Sciatic Neuropathy RGD PMID:16251448 RGD:7387272 NCBI chr 2:15,793,257...15,819,151
Ensembl chr 2:15,791,451...15,819,138
JBrowse link
G F2R coagulation factor II thrombin receptor severity ISO RGD PMID:11877315, PMID:12717003, PMID:19674841 RGD:7387269, RGD:7387270, RGD:7387271 NCBI chr 2:85,642,794...85,659,133
Ensembl chr 2:85,641,474...85,656,636
JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit ISO protein:increased expression:dorsal horn of spinal cord, neuron
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:22160634, PMID:27093858 RGD:9999169 NCBI chr 7:98,449,508...98,451,971
Ensembl chr 7:98,449,349...98,455,554
JBrowse link
G GAL galanin and GMAP prepropeptide ISO CTD Direct Evidence: marker/mechanism CTD PMID:12787826 NCBI chr 2:4,351,113...4,357,167
Ensembl chr 2:4,350,909...4,357,170
JBrowse link
G GDNF glial cell derived neurotrophic factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:20457222 NCBI chr16:22,936,602...22,965,929
Ensembl chr16:22,936,601...22,965,886
JBrowse link
G GFAP glial fibrillary acidic protein ISO CTD Direct Evidence: marker/mechanism
associated with Spinal Cord Injuries;mRNA,protein:increased expression:brain,spinal cord:
CTD
RGD
PMID:16219025, PMID:27093858 RGD:8695957 NCBI chr12:18,456,268...18,466,594
Ensembl chr12:18,456,263...18,468,898
JBrowse link
G GFRA1 GDNF family receptor alpha 1 ISO RGD PMID:16464682 RGD:6218969 NCBI chr14:126,273,558...126,499,957
Ensembl chr14:126,277,857...126,499,465
JBrowse link
G GJA1 gap junction protein alpha 1 treatment ISO associated with Sciatic Neuropathy RGD PMID:23374942, PMID:24631560 RGD:8662447, RGD:8662456 NCBI chr 1:40,988,818...41,002,129
Ensembl chr 1:40,988,515...41,002,137
JBrowse link
G GP91-PHOX NADPH oxidase heavy chain subunit ISO associated with Spinal Cord Injuries; RGD PMID:20679217 RGD:11040629 NCBI chr  X:33,654,656...33,678,346
Ensembl chr  X:33,642,015...33,680,580
JBrowse link
G GRIN1 glutamate ionotropic receptor NMDA type subunit 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27093858
G GRIN2A glutamate ionotropic receptor NMDA type subunit 2A ISO RGD PMID:29758384 RGD:13792698 NCBI chr 3:32,749,329...33,149,350
Ensembl chr 3:32,752,351...33,143,499
JBrowse link
G GRIN2B glutamate ionotropic receptor NMDA type subunit 2B treatment ISO CTD Direct Evidence: marker/mechanism RGD
CTD
PMID:20042082, PMID:24204988 RGD:13210755 NCBI chr 5:58,477,862...58,948,735
Ensembl chr 5:58,480,526...58,927,583
JBrowse link
G GRK2 G protein-coupled receptor kinase 2 severity
treatment
ISO associated with Complex Regional Pain Syndromes
associated with bone cancer
RGD PMID:22796071, PMID:25466829, PMID:26064176, PMID:26935064 RGD:13513996, RGD:13514046, RGD:13514049, RGD:13792780 NCBI chr 2:5,209,435...5,227,543
Ensembl chr 2:5,209,436...5,227,748
JBrowse link
G GRM8 glutamate metabotropic receptor 8 ISO RGD PMID:17113112 RGD:6771186 NCBI chr18:20,945,049...21,756,952
Ensembl chr18:20,950,532...21,758,170
JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha ISO associated with Limb Ischemia;protein:increased expression:foot muscle, plantar RGD PMID:18691814 RGD:9068903 NCBI chr 1:190,625,436...190,673,926
Ensembl chr 1:190,625,181...190,674,850
JBrowse link
G HMGB1 high mobility group box 1 treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:24077211, PMID:27474498, PMID:30142543 RGD:13838658, RGD:7364865 NCBI chr11:7,195,556...7,321,071 JBrowse link
G HOXD1 homeobox D1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21151121 NCBI chr15:81,987,618...81,990,026
Ensembl chr15:81,987,752...81,990,807
JBrowse link
G HTR2A 5-hydroxytryptamine receptor 2A ISO associated with Diabetic neuropathies;
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:17888573, PMID:18930597, PMID:20531396 RGD:7257680 NCBI chr11:20,555,939...20,620,225
Ensembl chr11:20,555,961...20,619,629
JBrowse link
G HTR7 5-hydroxytryptamine receptor 7 ISO RGD PMID:21693130, PMID:21843960 RGD:6480665, RGD:6482179 NCBI chr14:102,443,312...102,548,894
Ensembl chr14:102,444,566...102,548,931
JBrowse link
G IGF1 insulin like growth factor 1 ISO CTD Direct Evidence: therapeutic CTD PMID:9452187 NCBI chr 5:81,762,027...81,909,253
Ensembl chr 5:81,775,970...81,848,037
JBrowse link
G IL10 interleukin 10 treatment ISO associated with Sciatic Neuropathy
CTD Direct Evidence: marker/mechanism|therapeutic
RGD
CTD
PMID:7582491, PMID:17174526, PMID:22820166, PMID:23957449, PMID:24077211 RGD:7364792, RGD:7364827, RGD:7364865 NCBI chr 9:67,400,727...67,405,941
Ensembl chr 9:67,400,727...67,405,711
JBrowse link
G IL13 interleukin 13 treatment ISO RGD PMID:11399514 RGD:8549555 NCBI chr 2:134,972,099...134,976,672
Ensembl chr 2:134,972,623...134,975,093
JBrowse link
G IL17A interleukin 17A treatment ISO RGD PMID:23192794, PMID:23246025 RGD:9068942, RGD:9222699 NCBI chr 7:46,013,584...46,017,161
Ensembl chr 7:46,013,584...46,017,153
JBrowse link
G IL18 interleukin 18 treatment ISO associated with Peripheral Nerve Injuries RGD PMID:19036970 RGD:8655929 NCBI chr 9:39,839,959...39,861,258
Ensembl chr 9:39,834,966...39,873,300
JBrowse link
G IL1A interleukin 1 alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:12727271 NCBI chr 3:43,718,320...43,731,668
Ensembl chr 3:43,718,368...43,731,119
JBrowse link
G IL1R1 interleukin 1 receptor type 1 ISO RGD PMID:11585580, PMID:19022353 RGD:8662898, RGD:8662903 NCBI chr 3:52,192,912...52,334,734
Ensembl chr 3:52,192,914...52,288,515
JBrowse link
G IL1RN interleukin 1 receptor antagonist severity
treatment
ISO associated with Arthritis, Experimental; rat model treated with human protein
CTD Direct Evidence: marker/mechanism|therapeutic
RGD
CTD
PMID:8864563, PMID:10903985, PMID:15317861, PMID:17174526, PMID:17959986, PMID:20937348, PMID:22933159, PMID:23092240 RGD:6909165, RGD:6909175, RGD:7401210, RGD:8549800
G IL2 interleukin 2 treatment ISO associated with Sciatic Neuropathy; mRNA,protein:increased expression:spinal cord: RGD PMID:12755376, PMID:18423867, PMID:22189457 RGD:8662973, RGD:8662977, RGD:8662980 NCBI chr 8:101,640,938...101,645,683
Ensembl chr 8:101,640,944...101,645,609
JBrowse link
G IL33 interleukin 33 ISO RGD PMID:29329586 RGD:40400909 NCBI chr 1:215,899,830...215,941,944
Ensembl chr 1:215,899,435...215,941,840
JBrowse link
G IL6 interleukin 6 ISO mRNA:increased expression:dorsal root ganglion
associated with Foot Injuries; protein:increased expression:serum:
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:7582491, PMID:10401557, PMID:18652822, PMID:18988309, PMID:23953943 RGD:10402830, RGD:8662979 NCBI chr 9:91,506,421...91,510,830
Ensembl chr 9:91,506,340...91,511,263
JBrowse link
G IL6R interleukin 6 receptor ISO mRNA:increased expression:dorsal root ganglion RGD PMID:23953943 RGD:10402830 NCBI chr 4:95,322,426...95,381,393
Ensembl chr 4:95,322,426...95,381,282
JBrowse link
G INSR insulin receptor treatment ISO associated with Diabetic Neuropathies
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:18331706, PMID:23511693 RGD:10403050 NCBI chr 2:71,797,209...71,939,923
Ensembl chr 2:71,797,204...71,936,139
JBrowse link
G ITGA1 integrin subunit alpha 1 ISO PGE2-induced
knock-down using a specific monoclonal antibody or RNAi
RGD PMID:14984413, PMID:15836982 RGD:2302139, RGD:2302389 NCBI chr16:32,130,265...32,309,917
Ensembl chr16:32,130,235...32,304,592
JBrowse link
G ITGA2 integrin subunit alpha 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18234883 NCBI chr16:32,336,240...32,440,311
Ensembl chr16:32,336,292...32,437,103
JBrowse link
G ITGA3 integrin subunit alpha 3 ISO knock-down using a specific monoclonal antibody or RNAi RGD PMID:14984413, PMID:15836982 RGD:2302139, RGD:2302389 NCBI chr12:26,234,769...26,269,327
Ensembl chr12:26,234,753...26,271,561
JBrowse link
G ITGA5 integrin subunit alpha 5 ISO epinephrine-induced
knock-down using a specific monoclonal antibody or RNAi
RGD PMID:14984413, PMID:15836982 RGD:2302139, RGD:2302389 NCBI chr 5:19,587,361...19,610,580
Ensembl chr 5:19,586,746...19,610,362
JBrowse link
G ITGB1 integrin subunit beta 1 ISO knock-down using a specific monoclonal antibody or RNAi RGD PMID:14984413, PMID:15836982 RGD:2302139, RGD:2302389 NCBI chr10:56,078,393...56,130,608
Ensembl chr10:56,078,398...56,173,795
JBrowse link
G ITPR1 inositol 1,4,5-trisphosphate receptor type 1 ISO RGD PMID:25972297 RGD:13793383 NCBI chr13:61,068,131...61,398,918
Ensembl chr13:61,068,126...61,398,908
JBrowse link
G JAK2 Janus kinase 2 treatment ISO associated with Diabetic Neuropathies RGD PMID:18636982, PMID:23511693 RGD:10403050, RGD:6483031 NCBI chr 1:216,849,744...217,002,310
Ensembl chr 1:216,848,686...217,002,148
JBrowse link
G JAK3 Janus kinase 3 treatment ISO RGD PMID:21434883 RGD:11533942 NCBI chr 2:59,905,901...59,926,504
Ensembl chr 2:59,905,919...59,926,495
JBrowse link
G KCNC4 potassium voltage-gated channel subfamily C member 4 ISO RGD PMID:17855600 RGD:10411908 NCBI chr 4:109,885,116...109,908,518
Ensembl chr 4:109,885,116...109,908,476
JBrowse link
G KCNK2 potassium two pore domain channel subfamily K member 2 ISO RGD PMID:16675954 RGD:9831112 NCBI chr 9:128,429,232...128,659,662
Ensembl chr 9:128,357,160...128,659,717
JBrowse link
G KCNQ3 potassium voltage-gated channel subfamily Q member 3 ISO associated with Bone Neoplasms;protein:decreased expression:dorsal root ganglia (rat) RGD PMID:23352759 RGD:9686417 NCBI chr 4:8,669,969...8,978,656
Ensembl chr 4:8,670,176...8,970,342
JBrowse link
G KMO kynurenine 3-monooxygenase treatment ISO RGD PMID:26524415 RGD:13703043 NCBI chr10:12,442,877...12,489,417
Ensembl chr10:12,431,982...12,490,409
JBrowse link
G KNG1 kininogen 1 ISO CTD Direct Evidence: marker/mechanism RGD
CTD
PMID:2010815, PMID:2128375, PMID:3061568, PMID:7493622, PMID:7582491, PMID:7881729, PMID:9714424, PMID:9720808, PMID:10401557, PMID:10499367, PMID:10543429, PMID:15626726, PMID:16259764, PMID:16793879, PMID:18234883, PMID:20868656, PMID:21521205 RGD:11059894 NCBI chr13:124,521,276...124,557,384
Ensembl chr13:124,521,277...124,557,376
JBrowse link
G LOC110258578 interleukin-1 beta-like ISO associated with Peripheral Nerve Injuries
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:7582491, PMID:8741165, PMID:10401557, PMID:12727271, PMID:15317861, PMID:17320857, PMID:20937348, PMID:22265659, PMID:23159984, PMID:27093858 RGD:1626676, RGD:6482671, RGD:7175548, RGD:7401209
G MAP1LC3A microtubule associated protein 1 light chain 3 alpha ISO RGD PMID:23665054 RGD:11560531 NCBI chr17:37,957,830...37,959,505
Ensembl chr17:37,957,507...37,959,505
JBrowse link
G MAP2K3 mitogen-activated protein kinase kinase 3 onset ISO RGD PMID:19427893 RGD:7495807 NCBI chr12:61,396,337...61,417,333
Ensembl chr12:61,396,331...61,421,579
JBrowse link
G MAPK1 mitogen-activated protein kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12941468, PMID:27093858 NCBI chr14:50,083,079...50,165,528
Ensembl chr14:50,082,896...50,165,523
JBrowse link
G MAPK3 mitogen-activated protein kinase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12941468, PMID:27093858 NCBI chr 3:18,291,444...18,299,410
Ensembl chr 3:18,291,445...18,299,567
JBrowse link
G MAPK7 mitogen-activated protein kinase 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17237256 NCBI chr12:60,144,138...60,148,743
Ensembl chr12:60,128,686...60,149,270
JBrowse link
G MAPK8 mitogen-activated protein kinase 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27093858 NCBI chr14:88,988,914...89,108,875
Ensembl chr14:88,988,949...89,172,200
JBrowse link
G MAPK9 mitogen-activated protein kinase 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27093858 NCBI chr 2:78,338,466...78,399,108
Ensembl chr 2:78,338,369...78,399,105
JBrowse link
G MC1R melanocortin 1 receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:19996949 NCBI chr 6:181,225...182,187
Ensembl chr 6:181,225...182,187
JBrowse link
G MC4R melanocortin 4 receptor ISO protein:increased expression:dorsal root ganglia (rat) RGD PMID:20081244 RGD:6484233 NCBI chr 1:160,772,013...160,774,124
Ensembl chr 1:160,772,013...160,774,124
JBrowse link
G MEN1 menin 1 ISO associated with Sciatic Neuropathy;protein:increased expression:spinal cord dorsal horn (rat) RGD PMID:20369282 RGD:9589142 NCBI chr 2:7,358,130...7,364,952
Ensembl chr 2:7,357,951...7,365,128
JBrowse link
G MFN2 mitofusin 2 ISO CTD Direct Evidence: marker/mechanism
mRNA:decreased expression:spinal cord (rat)
CTD
RGD
PMID:28587902 RGD:12910704 NCBI chr 6:72,026,512...72,056,439
Ensembl chr 6:72,026,722...72,056,439
JBrowse link
G MIR15B microRNA mir-15b ISO RGD PMID:28012171 RGD:13782150 NCBI chr13:100,083,172...100,083,269
Ensembl chr13:100,083,172...100,083,269
JBrowse link
G MIR381 microRNA mir-381 treatment ISO RGD PMID:30142543 RGD:13838658
G MIR96 microRNA mir-96 treatment ISO associated with Sciatic Neuropathy RGD PMID:24234845 RGD:11553932 NCBI chr18:18,982,506...18,982,590
Ensembl chr18:18,982,506...18,982,590
JBrowse link
G MMP3 matrix metallopeptidase 3 ISO CTD Direct Evidence: marker/mechanism RGD
CTD
PMID:18754875, PMID:22056600 RGD:8693664 NCBI chr 9:33,446,969...33,453,995
Ensembl chr 9:33,411,065...33,454,000
JBrowse link
G MPZ myelin protein zero ISO CTD Direct Evidence: marker/mechanism CTD PMID:16676325 NCBI chr 4:89,174,107...89,179,556
Ensembl chr 4:89,169,311...89,179,925
JBrowse link
G MTOR mechanistic target of rapamycin kinase ISO RGD PMID:24382350 RGD:10040983 NCBI chr 6:71,286,989...71,412,913
Ensembl chr 6:71,286,989...71,412,888
JBrowse link
G NEFH neurofilament heavy treatment ISO RGD PMID:21071147 RGD:27226885 NCBI chr14:46,559,698...46,568,686
Ensembl chr14:46,559,860...46,569,910
JBrowse link
G NGF nerve growth factor treatment ISO associated with Cystitis
associated with Peripheral Nerve Injuries;
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:11425916, PMID:16203088, PMID:18448607, PMID:20457222, PMID:22839415 RGD:7242799, RGD:7242803, RGD:7242849, RGD:8657088 NCBI chr 4:105,256,691...105,307,843
Ensembl chr 4:105,256,417...105,307,842
JBrowse link
G NGFR nerve growth factor receptor treatment ISO associated with Brachial Plexus Neuropathies RGD PMID:23324933 RGD:10413898 NCBI chr12:25,699,410...25,720,355
Ensembl chr12:25,699,427...25,720,357
JBrowse link
G NOS1 nitric oxide synthase 1 ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:19300402, PMID:23909597 RGD:7257597 NCBI chr14:35,112,898...35,299,297
Ensembl chr14:35,113,184...35,295,972
JBrowse link
G NOS2 nitric oxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17989504, PMID:19300402 NCBI chr12:44,174,944...44,219,875
Ensembl chr12:44,174,944...44,327,111
JBrowse link
G NPY neuropeptide Y treatment ISO associated with Sciatic Neuropathy RGD PMID:19556004 RGD:10448929 NCBI chr18:47,985,796...47,993,726
Ensembl chr18:47,985,725...47,993,289
JBrowse link
G NRG1 neuregulin 1 ISO associated with Sciatic Neuropathy RGD PMID:22212401 RGD:10449019 NCBI chr15:52,625,550...53,688,003
Ensembl chr15:52,627,334...53,688,332
JBrowse link
G NTF3 neurotrophin 3 ISO CTD Direct Evidence: therapeutic CTD PMID:15659614 NCBI chr 5:65,052,608...65,122,645
Ensembl chr 5:65,052,517...65,123,788
JBrowse link
G NTRK1 neurotrophic receptor tyrosine kinase 1 ISO RGD PMID:17667845, PMID:20351485 RGD:5144120, RGD:5684352 NCBI chr 4:93,219,509...93,237,944
Ensembl chr 4:93,219,516...93,237,930
JBrowse link
G NTRK2 neurotrophic receptor tyrosine kinase 2 ISO associated with inflammation;protein:increased expression:dorsal root ganglion: RGD PMID:12470870, PMID:21958434 RGD:8657091, RGD:8657122 NCBI chr10:30,030,050...30,429,938
Ensembl chr10:30,033,379...30,429,882
JBrowse link
G NTSR1 neurotensin receptor 1 ISO RGD PMID:22396077 RGD:9743902 NCBI chr17:61,989,601...62,038,299
Ensembl chr17:61,989,112...62,035,345
JBrowse link
G OPRK1 opioid receptor kappa 1 treatment ISO associated with Diabetes Mellitus, Experimental; RGD PMID:16924480 RGD:9834947 NCBI chr 4:77,399,298...77,429,025
Ensembl chr 4:77,399,198...77,426,522
JBrowse link
G OPRL1 opioid related nociceptin receptor 1 ISO associated with Sciatic Neuropathy;mRNA:increased expression:spinal cord lumbar segment,dorsal root ganglion: RGD PMID:12106803 RGD:9835017 NCBI chr17:62,905,700...62,913,018
Ensembl chr17:62,897,727...62,913,754
JBrowse link
G OPRM1 opioid receptor mu 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17996026 NCBI chr 1:12,634,125...12,702,295
Ensembl chr 1:12,528,672...12,702,443
JBrowse link
G P2RX2 purinergic receptor P2X 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19383439 NCBI chr14:22,854,828...22,858,574
Ensembl chr14:22,854,828...22,858,386
JBrowse link
G P2RX3 purinergic receptor P2X 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19383439 NCBI chr 2:13,584,913...13,619,652
Ensembl chr 2:13,585,926...13,617,769
JBrowse link
G P2RY12 purinergic receptor P2Y12 ISO RGD PMID:20136836, PMID:20398327 RGD:6480525, RGD:6480526 NCBI chr13:91,522,754...91,572,195
Ensembl chr13:91,427,197...91,572,170
JBrowse link
G PAWR pro-apoptotic WT1 regulator treatment ISO RGD PMID:17179954 RGD:9835416 NCBI chr 5:101,693,145...101,797,842
Ensembl chr 5:101,692,143...101,797,835
JBrowse link
G PDYN prodynorphin ISO CTD Direct Evidence: marker/mechanism CTD PMID:17670969 NCBI chr17:33,505,075...33,521,534
Ensembl chr17:33,505,079...33,521,533
JBrowse link
G PENK proenkephalin treatment ISO associated with Diabetes Mellitus, Experimental; RGD PMID:23235561 RGD:10003116 NCBI chr 4:75,525,497...75,530,403
Ensembl chr 4:75,525,555...75,561,444
JBrowse link
G PLA2G4A phospholipase A2 group IVA ISO RGD PMID:16203828 RGD:1642461 NCBI chr 9:127,853,581...128,164,825
Ensembl chr 9:127,859,051...128,162,636
JBrowse link
G PNOC prepronociceptin ISO CTD Direct Evidence: marker/mechanism CTD PMID:12665541, PMID:19231294 NCBI chr14:12,101,223...12,134,174
Ensembl chr14:12,101,698...12,133,779
JBrowse link
G PPP2CA protein phosphatase 2 catalytic subunit alpha ISO RGD PMID:26732138 RGD:11572421 NCBI chr 2:136,497,780...136,522,630
Ensembl chr 2:136,494,541...136,522,646
JBrowse link
G PRKCB protein kinase C beta ISO associated with inflammation;protein:increased activity:spinal cord RGD PMID:16360284 RGD:1625519 NCBI chr 3:21,995,227...22,383,628
Ensembl chr 3:21,995,231...22,383,264
JBrowse link
G PRKCE protein kinase C epsilon ISO CTD Direct Evidence: marker/mechanism CTD PMID:11738263, PMID:12582831, PMID:20457222 NCBI chr 3:94,351,277...94,864,549
Ensembl chr 3:94,349,889...94,909,020
JBrowse link
G PRKCG protein kinase C gamma treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:12560106, PMID:19955894, PMID:27093858 RGD:28867224 NCBI chr 6:56,213,479...56,235,683
Ensembl chr 6:56,213,483...56,234,656
JBrowse link
G PRKCZ protein kinase C zeta ISO CTD Direct Evidence: marker/mechanism CTD PMID:27899695 NCBI chr 6:64,073,343...64,159,187
Ensembl chr 6:64,068,575...64,163,472
JBrowse link
G PRKG1 protein kinase cGMP-dependent 1 treatment ISO RGD PMID:14973199 RGD:7775058 NCBI chr14:97,558,531...98,793,080
Ensembl chr14:97,560,785...98,793,318
JBrowse link
G PROK2 prokineticin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16793879 NCBI chr13:53,169,040...53,184,695
Ensembl chr13:53,169,437...53,185,115
JBrowse link
G PROKR1 prokineticin receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16793879 NCBI chr 3:73,689,583...73,711,410
Ensembl chr 3:73,690,139...73,788,315
JBrowse link
G PTAFR platelet activating factor receptor treatment ISO RGD PMID:16925995 RGD:10041052 NCBI chr 6:85,235,390...85,272,360
Ensembl chr 6:85,235,390...85,272,333
JBrowse link
G PTGER1 prostaglandin E receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11375261 NCBI chr 2:64,796,944...64,800,199
Ensembl chr 2:64,797,220...64,800,459
JBrowse link
G PTGER3 prostaglandin E receptor 3 ISO protein:increased expression:lumbar spinal cord dorsal horn (rat) RGD PMID:17413918 RGD:5688169 NCBI chr 6:141,958,955...142,160,437
Ensembl chr 6:141,958,954...142,161,292
JBrowse link
G PTGER4 prostaglandin E receptor 4 treatment ISO RGD PMID:20423341 RGD:10003041 NCBI chr16:25,670,832...25,686,556
Ensembl chr16:25,670,862...25,686,552
JBrowse link
G PTGES3 prostaglandin E synthase 3 ISO RGD PMID:16192391 RGD:5688057 NCBI chr 5:22,000,335...22,022,830
Ensembl chr 5:22,000,339...22,021,663
JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:spinal cord
CTD
RGD
PMID:17413918, PMID:17989504 RGD:5688169 NCBI chr 1:262,456,106...262,482,159
Ensembl chr 1:262,456,155...262,483,035
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:15464832, PMID:17112505, PMID:17989504 RGD:5688224 NCBI chr 9:127,850,164...127,858,866
Ensembl chr 9:127,850,013...127,858,884
JBrowse link
G PTHLH parathyroid hormone like hormone ISO CTD Direct Evidence: marker/mechanism CTD PMID:16769263 NCBI chr 5:45,750,968...45,763,421
Ensembl chr 5:45,751,292...45,763,415
JBrowse link
G RAF1 Raf-1 proto-oncogene, serine/threonine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:18976650 NCBI chr13:68,581,128...68,657,911
Ensembl chr13:68,580,812...68,657,829
JBrowse link
G RGS4 regulator of G protein signaling 4 treatment ISO associated with lesion of sciatic nerve RGD PMID:27641322 RGD:13524513 NCBI chr 4:87,383,336...87,390,478
Ensembl chr 4:87,381,386...87,390,467
JBrowse link
G SCN10A sodium voltage-gated channel alpha subunit 10 ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:16545521, PMID:19070548 RGD:6484253 NCBI chr13:23,481,537...23,570,454
Ensembl chr13:23,481,999...23,570,452
JBrowse link
G SCN11A sodium voltage-gated channel alpha subunit 11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23264124 NCBI chr13:23,602,378...23,692,281
Ensembl chr13:23,602,977...23,692,220
JBrowse link
G SIN3A SIN3 transcription regulator family member A ISO associated with Arthritis, Experimental;mRNA:decreased expression:spinal cord, neuron RGD PMID:17553988 RGD:9495916 NCBI chr 7:58,171,821...58,246,126
Ensembl chr 7:58,176,166...58,245,762
JBrowse link
G SLC12A5 solute carrier family 12 member 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20086212 NCBI chr17:48,192,072...48,230,674
Ensembl chr17:48,191,988...48,231,294
JBrowse link
G SLC17A8 solute carrier family 17 member 8 ISO protein:increased expression:dorsal horn of spinal cord, neuron RGD PMID:22160634 RGD:9999169 NCBI chr 5:83,741,641...83,809,472
Ensembl chr 5:83,741,715...83,800,809
JBrowse link
G SPARC secreted protein acidic and cysteine rich ISO CTD Direct Evidence: marker/mechanism CTD PMID:20714283 NCBI chr16:71,368,164...71,380,972
Ensembl chr16:71,357,703...71,381,160
JBrowse link
G STAT3 signal transducer and activator of transcription 3 treatment ISO RGD PMID:24098399 RGD:8694290 NCBI chr12:20,407,316...20,471,091
Ensembl chr12:20,407,233...20,472,993
JBrowse link
G SYN2 synapsin II ISO CTD Direct Evidence: marker/mechanism CTD PMID:18701217 NCBI chr13:68,050,015...68,221,504
Ensembl chr13:68,050,186...68,221,496
JBrowse link
G TAC1 tachykinin precursor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:8864563, PMID:9714424, PMID:10499367, PMID:12351280, PMID:12787826, PMID:15626726, PMID:16259764, PMID:18234883, PMID:19231294 NCBI chr 9:77,197,403...77,206,529
Ensembl chr 9:77,197,535...77,206,526
JBrowse link
G TACR1 tachykinin receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15964684, PMID:17123731 NCBI chr 3:67,839,367...68,021,733
Ensembl chr 3:67,839,411...68,021,728
JBrowse link
G TGFBR1 transforming growth factor beta receptor 1 ISO associated with Experimental Pancreatitis, Chronic RGD PMID:26645248 RGD:14995470 NCBI chr 1:240,842,735...240,918,267
Ensembl chr 1:240,859,270...240,918,528
JBrowse link
G THBD thrombomodulin treatment ISO CTD Direct Evidence: therapeutic
associated with Inflammation
CTD
RGD
PMID:24004409, PMID:27474498 RGD:11038687 NCBI chr17:30,219,870...30,223,499
Ensembl chr17:30,221,819...30,230,177
JBrowse link
G TLR2 toll like receptor 2 ISO RGD PMID:17355971, PMID:24204973 RGD:8553059, RGD:8553185 NCBI chr 8:75,416,257...75,428,370
Ensembl chr 8:75,411,991...75,446,850
JBrowse link
G TLR4 toll like receptor 4 ISO RGD PMID:15809417, PMID:20714435, PMID:24204973 RGD:4144070, RGD:7815040, RGD:8553185 NCBI chr 1:258,044,610...258,054,641
Ensembl chr 1:258,044,610...258,059,004
JBrowse link
G TNF tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism
associated with Diabetic Neuropathies;
mRNA,protein:increased expression:spinal cord:
protein:increased expression:lumbar vertebra:
RGD
CTD
PMID:7582491, PMID:7881729, PMID:10401557, PMID:10825476, PMID:12727271, PMID:16472913, PMID:16675114, PMID:17304130, PMID:17320857, PMID:17459378, PMID:18463260, PMID:18582539, PMID:18790011, PMID:20383154, PMID:21104419, PMID:26141506, PMID:27093858 RGD:7387300, RGD:7387302, RGD:7394737, RGD:7394741, RGD:7394757, RGD:7401179 NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,636...23,703,655
JBrowse link
G TNFRSF11B TNF receptor superfamily member 11b ISO CTD Direct Evidence: therapeutic CTD PMID:16769263 NCBI chr 4:19,850,212...19,879,132 JBrowse link
G TNFRSF1A TNF receptor superfamily member 1A treatment ISO associated with Sciatic Neuropathy RGD PMID:12752784, PMID:20417692, PMID:21145890, PMID:21712071, PMID:22652595, PMID:24257399 RGD:5130913, RGD:5130939, RGD:8548873, RGD:8661726, RGD:8661737, RGD:8661750 NCBI chr 5:64,319,349...64,331,876
Ensembl chr 5:64,319,073...64,331,909
JBrowse link
G TNFRSF1B TNF receptor superfamily member 1B ISO associated with Sciatic Neuropathy RGD PMID:18463260, PMID:22652595 RGD:5130960, RGD:8661750 NCBI chr 6:72,195,420...72,231,146
Ensembl chr 6:72,195,435...72,231,149
JBrowse link
G TRPA1 transient receptor potential cation channel subfamily A member 1 ISO associated with Peripheral Nerve Injuries;
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:18234885, PMID:18954467, PMID:21481532, PMID:23523557 RGD:10043618 NCBI chr 4:63,493,374...63,558,486
Ensembl chr 4:63,306,738...63,558,485
JBrowse link
G TRPC1 transient receptor potential cation channel subfamily C member 1 ISO associated with Inflammation RGD PMID:19439599 RGD:7247605 NCBI chr13:83,436,343...83,498,419
Ensembl chr13:83,436,395...83,498,422
JBrowse link
G TRPC6 transient receptor potential cation channel subfamily C member 6 ISO RGD PMID:19439599 RGD:7247605 NCBI chr 9:32,332,768...32,439,184
Ensembl chr 9:32,332,769...32,439,184
JBrowse link
G TRPV1 transient receptor potential cation channel subfamily V member 1 ISO associated with inflammation;protein:increased expression:dorsal root ganglion:
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:12151517, PMID:18234885, PMID:18774343, PMID:21958434, PMID:23006841 RGD:8657122 NCBI chr12:49,676,536...49,709,634
Ensembl chr12:49,677,291...49,701,325
JBrowse link
G TRPV4 transient receptor potential cation channel subfamily V member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18234883 NCBI chr14:41,125,819...41,169,582
Ensembl chr14:41,125,869...41,169,582
JBrowse link
G VIP vasoactive intestinal peptide ISO CTD Direct Evidence: marker/mechanism CTD PMID:12787826 NCBI chr 1:13,611,786...13,620,250
Ensembl chr 1:13,611,311...13,620,269
JBrowse link
Hyperesthesia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KNG1 kininogen 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:8190269 NCBI chr13:124,521,276...124,557,384
Ensembl chr13:124,521,277...124,557,376
JBrowse link
Hypesthesia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DARS2 aspartyl-tRNA synthetase 2, mitochondrial ISO ClinVar Annotator: match by term: Hypoesthesia ClinVar PMID:17384640, PMID:19592391, PMID:22843165, PMID:23065766, PMID:23652419, PMID:24005482, PMID:24407472, PMID:25741868, PMID:30311386 NCBI chr 9:116,109,970...116,140,635
Ensembl chr 9:116,109,982...116,139,427
JBrowse link
G DMD dystrophin ISO ClinVar Annotator: match by term: Hypoesthesia ClinVar PMID:23352160, PMID:23871722, PMID:26467025, PMID:26743743, PMID:26990548, PMID:28492532, PMID:30311386, PMID:30415094 NCBI chr  X:27,028,223...29,650,728
Ensembl chr  X:27,028,223...29,181,689
JBrowse link
G FIG4 FIG4 phosphoinositide 5-phosphatase ISO ClinVar Annotator: match by term: Hypoesthesia ClinVar PMID:26467025, PMID:28492532, PMID:29650794, PMID:30311386 NCBI chr 1:75,694,151...75,847,021
Ensembl chr 1:75,692,932...75,847,528
JBrowse link
G GJB1 gap junction protein beta 1 ISO ClinVar Annotator: match by term: Hypoesthesia ClinVar PMID:25741868, PMID:30311386 NCBI chr  X:57,241,990...57,249,496
Ensembl chr  X:57,196,999...57,249,886
JBrowse link
Hypoalgesia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AQP4 aquaporin 4 ISO RGD PMID:20851747 RGD:8696005 NCBI chr 6:111,407,632...111,422,169
Ensembl chr 6:111,400,794...111,422,042
JBrowse link
G HDAC4 histone deacetylase 4 ISO RGD PMID:19672313 RGD:9681457 NCBI chr15:138,378,237...138,657,266
Ensembl chr15:138,381,627...138,614,301
JBrowse link
ocular melanoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GNA11 G protein subunit alpha 11 ISO ClinVar Annotator: match by term: Intraocular melanoma ClinVar PMID:1328859, PMID:2549426, PMID:21083380, PMID:21444680, PMID:22733540, PMID:22808163, PMID:24141786, PMID:25157968, PMID:26619011 NCBI chr 2:75,439,405...75,456,855
Ensembl chr 2:75,437,201...75,457,092
JBrowse link
G GNAQ G protein subunit alpha q ISO ClinVar Annotator: match by term: Intraocular melanoma ClinVar PMID:1328859, PMID:2549426, PMID:18719078, PMID:19078957, PMID:21083380, PMID:22253748, PMID:22653968, PMID:22733540, PMID:22808163, PMID:25157968 NCBI chr 1:230,607,469...230,906,988
Ensembl chr 1:230,605,229...230,907,675
JBrowse link
Paresthesia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CAPN3 calpain 3 ISO ClinVar Annotator: match by term: Paresthesias ClinVar PMID:7720071, PMID:9266733, PMID:10330340, PMID:10679950, PMID:14578192, PMID:14981715, PMID:15351423, PMID:15689361, PMID:15725583, PMID:16100770, PMID:16141003, PMID:16650086, PMID:17318636, PMID:20635405, PMID:21204801, PMID:21984748, PMID:25741868, PMID:26467025, PMID:27142102, PMID:28492532, PMID:30311386 NCBI chr 1:128,960,117...129,013,508
Ensembl chr 1:128,960,121...129,013,547
JBrowse link
G FKRP fukutin related protein ISO ClinVar Annotator: match by term: Paresthesias ClinVar PMID:11741828, PMID:12666124, PMID:14647208, PMID:15060126, PMID:15574464, PMID:15580560, PMID:15833432, PMID:15886712, PMID:16634037, PMID:16786213, PMID:17554798, PMID:18060779, PMID:18593008, PMID:18639457, PMID:19820980, PMID:19835634, PMID:19900540, PMID:21220724, PMID:21228398, PMID:22264518, PMID:22981120, PMID:23576288, PMID:23591631, PMID:24033266, PMID:24447024, PMID:25048216, PMID:25560911, PMID:25741868, PMID:26363967, PMID:26467025, PMID:26574668, PMID:26833294, PMID:28492532, PMID:30311386 NCBI chr 6:52,627,466...52,639,255
Ensembl chr 6:52,627,482...52,639,255
JBrowse link
G INS insulin ISO CTD Direct Evidence: marker/mechanism CTD PMID:9861226 NCBI chr 2:1,496,842...1,498,052
Ensembl chr 2:1,496,842...1,497,841
JBrowse link
G PMP22 peripheral myelin protein 22 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12427913 NCBI chr12:58,679,773...58,734,195
Ensembl chr12:58,679,776...58,707,953
JBrowse link
retinoblastoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALK ALK receptor tyrosine kinase ISO ClinVar Annotator: match by term: Retinoblastoma ClinVar PMID:25741868, PMID:28492532 NCBI chr 3:109,411,146...110,105,755 JBrowse link
G APC APC regulator of WNT signaling pathway ISO ClinVar Annotator: match by term: Retinoblastoma ClinVar PMID:25186627, PMID:25741868, PMID:28492532 NCBI chr 2:116,913,354...116,985,303
Ensembl chr 2:116,812,582...117,034,912
JBrowse link
G BRCA2 BRCA2 DNA repair associated ISO ClinVar Annotator: match by term: Retinoblastoma ClinVar PMID:17899372, PMID:19043619, PMID:20507642, PMID:22632462, PMID:25741868, PMID:25782689, PMID:28492532, PMID:29394989, PMID:29884841, PMID:30254663 NCBI chr11:8,805,950...8,858,128 JBrowse link
G CADM2 cell adhesion molecule 2 ISO mRNA, protein:decreased expression:retina RGD PMID:30320366 RGD:15092072 NCBI chr13:169,681,947...170,753,114
Ensembl chr13:169,688,940...170,752,425
JBrowse link
G FANCM FA complementation group M ISO ClinVar Annotator: match by term: Retinoblastoma ClinVar PMID:25741868 NCBI chr 1:175,333,965...175,402,065
Ensembl chr 1:175,334,047...175,445,650
JBrowse link
G FAS Fas cell surface death receptor severity ISO protein:decreased expression:tumor (human) RGD PMID:14533029 RGD:8662811 NCBI chr14:100,927,305...100,954,781 JBrowse link
G ITM2B integral membrane protein 2B ISO ClinVar Annotator: match by term: Retinoblastoma ClinVar PMID:8099255, PMID:12541220, PMID:28492532, PMID:28575107, PMID:29568217 NCBI chr11:19,349,088...19,377,931
Ensembl chr11:19,349,133...19,377,917
JBrowse link
G KDM1B lysine demethylase 1B ISO mRNA:increased expression:retina (human) RGD PMID:16180235 RGD:9588276 NCBI chr 7:13,846,283...13,902,912
Ensembl chr 7:13,845,942...13,901,263
JBrowse link
G LPAR6 lysophosphatidic acid receptor 6 ISO ClinVar Annotator: match by term: Retinoblastoma ClinVar PMID:8099255, PMID:12541220, PMID:21505449, PMID:22909775, PMID:23301675, PMID:28492532, PMID:28575107, PMID:29568217 NCBI chr11:19,216,305...19,220,913 JBrowse link
G MAX MYC associated factor X ISO ClinVar Annotator: match by term: Retinoblastoma ClinVar PMID:25741868, PMID:28492532 NCBI chr 7:89,142,966...89,168,265
Ensembl chr 7:89,120,822...89,168,270
JBrowse link
G MED4 mediator complex subunit 4 ISO ClinVar Annotator: match by term: Retinoblastoma ClinVar PMID:8099255, PMID:12541220, PMID:28492532, PMID:28575107, PMID:29568217 NCBI chr11:19,551,858...19,566,915
Ensembl chr11:19,551,863...19,566,926
JBrowse link
G MGMT O-6-methylguanine-DNA methyltransferase disease_progression ISO DNA:hypermethylation:promoter (human) RGD PMID:15799820 RGD:2317684 NCBI chr14:138,502,005...138,771,543
Ensembl chr14:138,499,161...138,779,938
JBrowse link
G MTR 5-methyltetrahydrofolate-homocysteine methyltransferase susceptibility ISO DNA:SNP::2756A>G(human) RGD PMID:20310006 RGD:8694083 NCBI chr14:54,546,978...54,652,780
Ensembl chr14:54,546,981...54,652,759
JBrowse link
G MUTYH mutY DNA glycosylase ISO ClinVar Annotator: match by term: Retinoblastoma ClinVar PMID:25741868, PMID:26947005, PMID:28135145, PMID:28492532 NCBI chr 6:166,002,853...166,012,191 JBrowse link
G NF1 neurofibromin 1 ISO ClinVar Annotator: match by term: Retinoblastoma ClinVar PMID:25741868, PMID:28492532 NCBI chr12:43,487,098...43,754,205
Ensembl chr12:43,489,171...43,754,176
JBrowse link
G NUDT15 nudix hydrolase 15 ISO ClinVar Annotator: match by term: Retinoblastoma ClinVar PMID:8099255, PMID:12541220, PMID:28492532, PMID:28575107, PMID:29568217 NCBI chr11:19,572,963...19,584,565
Ensembl chr11:19,572,644...19,584,538
JBrowse link
G P14ARF p14ARF protein ISO ClinVar Annotator: match by term: Retinoblastoma ClinVar PMID:25741868 NCBI chr 1:200,774,496...200,799,149
Ensembl chr 1:200,774,496...200,798,854
JBrowse link
G PALB2 partner and localizer of BRCA2 ISO ClinVar Annotator: match by term: Retinoblastoma ClinVar PMID:23555315, PMID:25741868, PMID:28492532 NCBI chr 3:22,586,881...22,612,837
Ensembl chr 3:22,586,856...22,612,835
JBrowse link
G PTCH1 patched 1 ISO ClinVar Annotator: match by term: Retinoblastoma ClinVar PMID:24728327, PMID:25741868, PMID:28492532 NCBI chr10:26,627,165...26,703,225
Ensembl chr10:26,627,325...26,703,225
JBrowse link
G RB1 RB transcriptional corepressor 1 ISO OMIM NCBI chr11:19,186,754...19,317,642
Ensembl chr11:19,186,759...19,317,690
JBrowse link
G SERPINF1 serpin family F member 1 treatment ISO human protein and tumor xenograft in a mouse model RGD PMID:19832843 RGD:8554870 NCBI chr12:47,949,004...47,959,471
Ensembl chr12:47,943,051...47,959,472
JBrowse link
G SNCG synuclein gamma ISO RGD PMID:18728752 RGD:6218971 NCBI chr14:87,916,353...87,922,111
Ensembl chr14:87,904,773...87,922,112
JBrowse link
G STK11 serine/threonine kinase 11 ISO ClinVar Annotator: match by term: Retinoblastoma ClinVar PMID:25741868, PMID:28135145, PMID:28492532 NCBI chr 2:77,229,888...77,249,322
Ensembl chr 2:77,230,372...77,249,327
JBrowse link
G TSC2 TSC complex subunit 2 ISO ClinVar Annotator: match by term: Retinoblastoma ClinVar PMID:22703879, PMID:25741868, PMID:28492532 NCBI chr 3:39,898,924...39,935,579
Ensembl chr 3:39,898,922...39,937,371
JBrowse link
trilateral retinoblastoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RB1 RB transcriptional corepressor 1 ISO ClinVar Annotator: match by term: Retinoblastoma, trilateral ClinVar PMID:7704558, PMID:8346255, PMID:8605116, PMID:9400934, PMID:16463005, PMID:22963398, PMID:24688104, PMID:25157968, PMID:25602518, PMID:25741868, PMID:28492532 NCBI chr11:19,186,754...19,317,642
Ensembl chr11:19,186,759...19,317,690
JBrowse link
uveal melanoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAP1 BRCA1 associated protein 1 disease_progression ISO mRNA,protein:decreased expression: :
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:21874000, PMID:25147369, PMID:25231345, PMID:26719535 RGD:9586037 NCBI chr13:34,544,570...34,553,538
Ensembl chr13:34,544,575...34,553,621
JBrowse link
G BRCA2 BRCA2 DNA repair associated susceptibility ISO DNA:mutations: : RGD PMID:22187320 RGD:9068467 NCBI chr11:8,805,950...8,858,128 JBrowse link
G CRP C-reactive protein, pentraxin-related disease_progression ISO RGD PMID:23057648 RGD:9491834 NCBI chr 4:90,793,361...90,801,020
Ensembl chr 4:90,722,352...90,805,236
JBrowse link
G CYSLTR2 cysteinyl leukotriene receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27089179 NCBI chr11:18,988,665...19,011,015
Ensembl chr11:18,987,174...19,011,015
JBrowse link
G EIF1AX eukaryotic translation initiation factor 1A X-linked ISO CTD Direct Evidence: marker/mechanism CTD PMID:23793026 NCBI chr  X:16,429,625...16,449,581
Ensembl chr  X:16,429,627...16,449,557
JBrowse link
G GNA11 G protein subunit alpha 11 ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Melanoma of the Uvea
CTD
ClinVar
PMID:1328859, PMID:2549426, PMID:21083380, PMID:21444680, PMID:22733540, PMID:22808163, PMID:24141786, PMID:25157968, PMID:26397223, PMID:26619011, PMID:27089179 NCBI chr 2:75,439,405...75,456,855
Ensembl chr 2:75,437,201...75,457,092
JBrowse link
G GNAQ G protein subunit alpha q ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Melanoma of the Uvea
CTD
ClinVar
PMID:1328859, PMID:2549426, PMID:18719078, PMID:19078957, PMID:21083380, PMID:22253748, PMID:22653968, PMID:22733540, PMID:22808163, PMID:25157968, PMID:26397223, PMID:27089179 NCBI chr 1:230,607,469...230,906,988
Ensembl chr 1:230,605,229...230,907,675
JBrowse link
G IGF1 insulin like growth factor 1 disease_progression ISO RGD PMID:23197685 RGD:8548834 NCBI chr 5:81,762,027...81,909,253
Ensembl chr 5:81,775,970...81,848,037
JBrowse link
G JMJD6 jumonji domain containing 6, arginine demethylase and lysine hydroxylase ISO CTD Direct Evidence: marker/mechanism CTD PMID:30619488 NCBI chr12:4,809,014...4,819,853
Ensembl chr12:4,808,691...4,818,062
JBrowse link
G KDM5B lysine demethylase 5B severity ISO protein:increased expression:uvea (human) RGD PMID:22669717 RGD:9587775 NCBI chr10:24,739,115...24,831,537
Ensembl chr10:24,736,834...24,831,447
JBrowse link
G KDR kinase insert domain receptor disease_progression ISO RGD PMID:21984395 RGD:8549718 NCBI chr 8:41,809,116...41,856,379
Ensembl chr 8:41,809,116...41,856,339
JBrowse link
G MCAM melanoma cell adhesion molecule disease_progression ISO RGD PMID:19958117 RGD:7364775 NCBI chr 9:46,506,375...46,522,091
Ensembl chr 9:46,512,784...46,522,083
JBrowse link
G PLCB4 phospholipase C beta 4 ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Uveal melanoma
CTD
ClinVar
PMID:27089179, PMID:31186267 NCBI chr17:17,915,984...18,402,540
Ensembl chr17:17,916,008...18,402,546
JBrowse link
G PRAME PRAME nuclear receptor transcriptional regulator severity ISO mRNA:increased expression:uvea (human) RGD PMID:27486988 RGD:11535039 NCBI chr14:48,901,097...48,906,855 JBrowse link
G SERPINE1 serpin family E member 1 treatment ISO human gene in mouse model RGD PMID:9326241 RGD:8547806 NCBI chr 3:8,863,738...8,871,572
Ensembl chr 3:8,863,695...8,871,564
JBrowse link
G SERPINF1 serpin family F member 1 severity ISO RGD PMID:23793989 RGD:8554893 NCBI chr12:47,949,004...47,959,471
Ensembl chr12:47,943,051...47,959,472
JBrowse link
G SF3B1 splicing factor 3b subunit 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23313955, PMID:23793026 NCBI chr15:101,274,968...101,338,018
Ensembl chr15:101,191,854...101,338,023
JBrowse link
G TMEM127 transmembrane protein 127 ISO ClinVar Annotator: match by term: Uveal melanoma ClinVar PMID:25741868, PMID:28492532 NCBI chr 3:46,966,858...47,017,659
Ensembl chr 3:46,966,890...47,017,659
JBrowse link
G VEGFA vascular endothelial growth factor A ISO protein:increased expression:iris, ciliary body, vitreous body; RGD PMID:11914216 RGD:7483591 NCBI chr 7:38,746,393...38,762,282
Ensembl chr 7:38,746,052...38,761,038
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 12641
    Pathological Conditions, Signs and Symptoms 7581
      Signs and Symptoms 4619
        Neurologic Manifestations 4007
          Sensation Disorders 976
            Somatosensory Disorders 312
              Benign Cerebellar Ataxia with Thermoanalgesia 0
              Distal Arthrogryposis, with Impaired Proprioception and Touch 1
              Hyperalgesia 193
              Hyperesthesia 1
              Hypesthesia + 4
              Hypoalgesia 2
              Paresthesia 4
              sensory system cancer + 109
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.