ONTOLOGY REPORT - ANNOTATIONS


Term:Liver Injury
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Accession:DOID:9008691 term browser browse the term
Definition:Damage to any part of the liver caused by physical, chemical, or biological agents which characteristically elicit inflammatory reaction
Synonyms:primary_id: RDO:9000017
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Liver Injury term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcg2 ATP binding cassette subfamily G member 2 JBrowse link 4 88,765,441 88,890,268 RGD:1304394
G Acta2 actin alpha 2, smooth muscle JBrowse link 1 252,537,614 252,550,394 RGD:12879446
G Adrb2 adrenoceptor beta 2 JBrowse link 18 57,513,792 57,515,834 RGD:8548508
G Atp5f1a ATP synthase F1 subunit alpha JBrowse link 18 74,156,553 74,164,490 RGD:13800895
G Atp5f1b ATP synthase F1 subunit beta JBrowse link 7 2,504,708 2,511,748 RGD:13800895
G Atp5pf ATP synthase peripheral stalk subunit F6 JBrowse link 11 24,286,806 24,294,419 RGD:13800895
G Ccr5 C-C motif chemokine receptor 5 JBrowse link 8 133,192,398 133,215,599 RGD:8552264
G Csf3 colony stimulating factor 3 JBrowse link 10 86,616,785 86,619,160 RGD:11039467
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 JBrowse link 8 62,451,360 62,458,244 RGD:11576319
G Enpp2 ectonucleotide pyrophosphatase/phosphodiesterase 2 JBrowse link 7 94,479,931 94,563,086 RGD:9685426
G Fbn1 fibrillin 1 JBrowse link 3 117,569,708 117,766,160 RGD:7794798
G Fgg fibrinogen gamma chain JBrowse link 2 181,987,080 181,994,523 RGD:11352697
G Fn1 fibronectin 1 JBrowse link 9 78,900,111 78,969,018 RGD:7205469
G G6pd glucose-6-phosphate dehydrogenase JBrowse link X 156,274,800 156,293,935 RGD:10449174
G Gck glucokinase JBrowse link 14 86,149,146 86,191,589 RGD:7488971
G Gclc glutamate-cysteine ligase, catalytic subunit JBrowse link 8 85,059,051 85,097,471 RGD:10402380
G Gclm glutamate cysteine ligase, modifier subunit JBrowse link 2 225,827,504 225,847,876 RGD:10402380
G Gfer growth factor, augmenter of liver regeneration JBrowse link 10 14,059,347 14,061,703 RGD:9685725
G Gpx1 glutathione peroxidase 1 JBrowse link 8 117,117,430 117,118,528 RGD:11353785
G Gsr glutathione-disulfide reductase JBrowse link 16 62,197,617 62,239,987 RGD:10401865
G Gsta4 glutathione S-transferase alpha 4 JBrowse link 8 85,497,557 85,514,732 RGD:10401911
G Hgf hepatocyte growth factor JBrowse link 4 15,435,460 15,505,377 RGD:8548597
G Hspb1 heat shock protein family B (small) member 1 JBrowse link 12 23,839,390 23,841,051 RGD:10402770
G Il18 interleukin 18 JBrowse link 8 55,009,666 55,016,286 RGD:8655972
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:11060263
RGD:11062142
G Jak2 Janus kinase 2 JBrowse link 1 247,398,667 247,457,521 RGD:8694328
G Mdh1 malate dehydrogenase 1 JBrowse link 14 106,378,349 106,393,642 RGD:13703104
G Mmp9 matrix metallopeptidase 9 JBrowse link 3 161,413,410 161,421,473 RGD:7207088
G Myc MYC proto-oncogene, bHLH transcription factor JBrowse link 7 102,586,313 102,591,240 RGD:7240702
G Npm1 nucleophosmin 1 JBrowse link 10 18,080,949 18,091,062 RGD:11534994
G Nudt1 nudix hydrolase 1 JBrowse link 12 16,391,578 16,398,771 RGD:10449034
G Pcna proliferating cell nuclear antigen JBrowse link 3 124,880,698 124,884,570 RGD:10448980
G Pdgfb platelet derived growth factor subunit B JBrowse link 7 121,215,458 121,233,092 RGD:10449498
G Sirt1 sirtuin 1 JBrowse link 20 26,831,971 26,851,587 RGD:9586016
G St6gal1 ST6 beta-galactoside alpha-2,6-sialyltransferase 1 JBrowse link 11 80,927,601 80,981,424 RGD:10043142
G Stat3 signal transducer and activator of transcription 3 JBrowse link 10 88,790,401 88,842,263 RGD:8694328
G Tfpi tissue factor pathway inhibitor JBrowse link 3 71,852,738 71,902,127 RGD:11341667
Liver Reperfusion Injury term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adipoq adiponectin, C1Q and collagen domain containing JBrowse link 11 81,330,845 81,344,488 RGD:8695935
G Adm adrenomedullin JBrowse link 1 175,443,189 175,447,260 RGD:7364958
G Ager advanced glycosylation end product-specific receptor JBrowse link 20 4,363,152 4,366,079 RGD:10402078
G Bad BCL2-associated agonist of cell death JBrowse link 1 222,198,516 222,207,459 RGD:10053673
RGD:10053710
G Bax BCL2 associated X, apoptosis regulator JBrowse link 1 101,451,801 101,457,207 RGD:10053673
RGD:5134995
RGD:10053710
G Bcl2 BCL2, apoptosis regulator JBrowse link 13 26,605,426 26,769,374 RGD:10053710
RGD:5134995
G Bcl2l1 Bcl2-like 1 JBrowse link 3 148,259,594 148,314,191 RGD:10053710
G C3 complement C3 JBrowse link 9 9,721,137 9,747,084 RGD:11040888
G Casp12 caspase 12 JBrowse link 8 2,658,892 2,686,160 RGD:13782166
G Casp8 caspase 8 JBrowse link 9 65,614,142 65,662,624 RGD:8661760
G Casp9 caspase 9 JBrowse link 5 160,356,211 160,373,774 RGD:13782358
G Ccl2 C-C motif chemokine ligand 2 JBrowse link 10 69,412,065 69,413,863 RGD:8549627
G Cd14 CD14 molecule JBrowse link 18 29,560,341 29,562,290 RGD:7183676
G Cd40 CD40 molecule JBrowse link 3 161,519,789 161,534,943 RGD:8547795
G Cfh complement factor H JBrowse link 13 56,979,155 57,080,540 RGD:7364958
G Cxcl1 C-X-C motif chemokine ligand 1 JBrowse link 14 18,743,678 18,745,457 RGD:5134995
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 JBrowse link 8 62,472,087 62,478,122 RGD:2314952
G Elane elastase, neutrophil expressed JBrowse link 7 12,638,320 12,640,168 RGD:10450560
G F3 coagulation factor III, tissue factor JBrowse link 2 225,310,686 225,322,281 RGD:11341708
G Fadd Fas associated via death domain JBrowse link 1 217,746,176 217,748,581 RGD:8661760
G Fas Fas cell surface death receptor JBrowse link 1 252,589,785 252,624,790 RGD:2290283
RGD:1600351
G Fga fibrinogen alpha chain JBrowse link 2 181,997,562 182,013,726 RGD:9685021
G Fn1 fibronectin 1 JBrowse link 9 78,900,111 78,969,018 RGD:7205470
G Gsk3b glycogen synthase kinase 3 beta JBrowse link 11 65,060,884 65,208,842 RGD:13792730
G Gstm1 glutathione S-transferase mu 1 JBrowse link 2 210,803,869 210,809,461 RGD:2314952
G H2afx H2A histone family, member X JBrowse link 8 48,665,652 48,666,981 RGD:8693718
G Hmgb1 high mobility group box 1 JBrowse link 12 7,082,529 7,090,246 RGD:10402068
RGD:10402175
RGD:10402078
G Hmox1 heme oxygenase 1 JBrowse link 19 14,508,634 14,515,455 RGD:10755725
G Hp haptoglobin JBrowse link 19 42,096,255 42,100,805 RGD:1626366
RGD:11041815
G Icam1 intercellular adhesion molecule 1 JBrowse link 8 22,035,287 22,047,049 RGD:11520784
G Ikbkg inhibitor of nuclear factor kappa B kinase regulatory subunit gamma JBrowse link X 156,254,187 156,280,046 RGD:12791280
G Il10 interleukin 10 JBrowse link 13 47,738,933 47,743,392 RGD:7364839
G Il1a interleukin 1 alpha JBrowse link 3 121,824,712 121,836,122 RGD:2314952
RGD:11059517
RGD:6907377
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:7175318
G Il1rn interleukin 1 receptor antagonist JBrowse link 3 1,449,778 1,468,624 RGD:6909138
RGD:8551710
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:11062134
G Jak2 Janus kinase 2 JBrowse link 1 247,398,667 247,457,521 RGD:10403073
G Lbp lipopolysaccharide binding protein JBrowse link 3 154,786,232 154,812,910 RGD:9685192
G Mapk8 mitogen-activated protein kinase 8 JBrowse link 16 9,620,854 9,709,342 RGD:10412680
G Mfn2 mitofusin 2 JBrowse link 5 164,684,244 164,715,414 RGD:12910833
RGD:13204829
G Mir223 microRNA 223 JBrowse link X 65,367,812 65,367,921 RGD:13831297
G Mmp15 matrix metallopeptidase 15 JBrowse link 19 10,079,881 10,101,380 RGD:2314952
G Mmp9 matrix metallopeptidase 9 JBrowse link 3 161,413,410 161,421,473 RGD:8547976
G Muc1 mucin 1, cell surface associated JBrowse link 2 188,543,137 188,547,874 RGD:7364757
G Muc3 mucin 3, intestinal JBrowse link 12 22,535,663 22,584,775 RGD:7364757
G Muc4 mucin 4, cell surface associated JBrowse link 11 71,242,973 71,285,217 RGD:7364757
G Nfe2l2 nuclear factor, erythroid 2-like 2 JBrowse link 3 62,497,568 62,525,146 RGD:10403073
G Nos3 nitric oxide synthase 3 JBrowse link 4 7,321,908 7,342,404 RGD:13450941
G Proc protein C, inactivator of coagulation factors Va and VIIIa JBrowse link 18 24,918,402 24,928,822 RGD:11100021
RGD:11100046
G Serpinc1 serpin family C member 1 JBrowse link 13 78,806,107 78,820,375 RGD:10450597
RGD:11038771
G Serpine1 serpin family E member 1 JBrowse link 12 22,641,104 22,651,482 RGD:8547901
G Serping1 serpin family G member 1 JBrowse link 3 72,161,230 72,171,109 RGD:1580273
G Sirt1 sirtuin 1 JBrowse link 20 26,831,971 26,851,587 RGD:9497542
G Slpi secretory leukocyte peptidase inhibitor JBrowse link 3 160,799,979 160,802,228 RGD:2314952
G Sod1 superoxide dismutase 1 JBrowse link 11 30,363,282 30,368,858 RGD:8655889
RGD:1581095
G Sod3 superoxide dismutase 3 JBrowse link 14 60,958,583 60,971,143 RGD:1581095
G Tert telomerase reverse transcriptase JBrowse link 1 32,250,876 32,275,330 RGD:11038676
G Tfpi tissue factor pathway inhibitor JBrowse link 3 71,852,738 71,902,127 RGD:11062061
G Tlr4 toll-like receptor 4 JBrowse link 5 82,587,424 82,601,056 RGD:10402078
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:10450597
G Tnfrsf1a TNF receptor superfamily member 1A JBrowse link 4 157,864,905 157,877,634 RGD:8661760
G Tradd TNFRSF1A-associated via death domain JBrowse link 19 37,214,461 37,221,099 RGD:8661760
G Ucp2 uncoupling protein 2 JBrowse link 1 165,506,375 165,512,744 RGD:7175309
G Xdh xanthine dehydrogenase JBrowse link 6 25,149,570 25,211,273 RGD:13209011

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 14875
    disease of anatomical entity 14051
      endocrine system disease 4668
        liver disease 2270
          Liver Injury 95
            Liver Reperfusion Injury 64
Path 2
Term Annotations click to browse term
  disease 14875
    disease of anatomical entity 14051
      gastrointestinal system disease 4251
        hepatobiliary disease 2359
          liver disease 2270
            Liver Injury 95
              Liver Reperfusion Injury 64
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.