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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Arbovirus Encephalitis
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Accession:DOID:9008926 term browser browse the term
Definition:Infections of the brain caused by arthropod-borne viruses (i.e., arboviruses) primarily from the families TOGAVIRIDAE; FLAVIVIRIDAE; BUNYAVIRIDAE; REOVIRIDAE; and RHABDOVIRIDAE. Life cycles of these viruses are characterized by ZOONOSES, with birds and lower mammals serving as intermediate hosts. The virus is transmitted to humans by the bite of mosquitoes (CULICIDAE) or TICKS. Clinical manifestations include fever, headache, alterations of mentation, focal neurologic deficits, and COMA. (From Clin Microbiol Rev 1994 Jan;7(1):89-116; Walton, Brain's Diseases of the Nervous System, 10th ed, p321)
Synonyms:exact_synonym: Arbovirus Encephalitides;   Arthropod Borne Encephalitis;   Arthropod Borne Viral Encephalitis;   Arthropod-Borne Encephalitides;   Arthropod-Borne Viral Encephalitides;   Mosquito Borne Encephalitis;   Mosquito-Borne Encephalitides
 primary_id: MESH:D004671
 alt_id: RDO:0005468
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants           Sort by:
 
Japanese encephalitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Camk2n1 calcium/calmodulin-dependent protein kinase II inhibitor 1 ISO RGD PMID:17010311 RGD:18337278 NCBI chr 5:156,876,706...156,878,486
Ensembl chr 5:156,876,706...156,878,486
JBrowse link
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma IMP RGD PMID:22251375 RGD:38599236 NCBI chr 6:51,465,696...51,501,234
Ensembl chr 6:51,465,908...51,498,337
JBrowse link
tick-borne encephalitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd40 CD40 molecule ISO protein:increased expression:cerebrospinal fluid (human) RGD PMID:16463218 RGD:11352252 NCBI chr 3:161,519,789...161,534,943
Ensembl chr 3:161,519,743...161,534,704
JBrowse link
G Cd40lg CD40 ligand ISO protein:increased expression:cerebrospinal fluid (human) RGD PMID:16463218 RGD:11352252 NCBI chr  X:159,703,703...159,714,886
Ensembl chr  X:159,703,578...159,716,562
JBrowse link
West Nile encephalitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sting1 stimulator of interferon response cGAMP interactor 1 severity ISO RGD PMID:31415679 RGD:39128224 NCBI chr18:28,529,537...28,535,828
Ensembl chr18:28,529,576...28,535,828
JBrowse link
West Nile fever term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccr5 C-C motif chemokine receptor 5 susceptibility ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: West nile virus, susceptibility to
OMIM
CTD
ClinVar
PMID:8639485, PMID:8751444, PMID:8756719, PMID:9055842, PMID:9132277, PMID:9140404, PMID:9207783, PMID:9466996, PMID:9511755, PMID:9585595, PMID:9600249, PMID:9768627, PMID:10520641, PMID:10615909, PMID:10803840, PMID:11081537, PMID:11403804, PMID:11403814, PMID:11517319, PMID:11781692, PMID:12874407, PMID:15744032, PMID:15863470, PMID:16216086, PMID:16248677, PMID:16418398, PMID:19017985, PMID:19073967, PMID:28492532 NCBI chr 8:133,192,398...133,215,599
Ensembl chr 8:133,197,032...133,215,614
JBrowse link
G S100b S100 calcium binding protein B ISO RGD PMID:19790244 RGD:5508797 NCBI chr20:13,130,633...13,142,856
Ensembl chr20:13,130,636...13,142,856
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 16023
    disease by infectious agent 1774
      viral infectious disease 1466
        Arbovirus Infections 40
          Arbovirus Encephalitis 7
            Eastern equine encephalitis 0
            Japanese encephalitis 2
            La Crosse encephalitis 0
            St. Louis encephalitis 0
            West Nile fever + 3
            tick-borne encephalitis + 2
Path 2
Term Annotations click to browse term
  disease 16023
    disease of anatomical entity 15278
      nervous system disease 10897
        central nervous system disease 9045
          brain disease 8370
            encephalitis 76
              Infectious Encephalitis 55
                viral encephalitis 55
                  Arbovirus Encephalitis 7
                    Eastern equine encephalitis 0
                    Japanese encephalitis 2
                    La Crosse encephalitis 0
                    St. Louis encephalitis 0
                    West Nile fever + 3
                    tick-borne encephalitis + 2
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.