ONTOLOGY REPORT - ANNOTATIONS


Term:visceral leishmaniasis
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Accession:DOID:9146 term browser browse the term
Definition:A chronic disease caused by LEISHMANIA DONOVANI and transmitted by the bite of several sandflies of the genera Phlebotomus and Lutzomyia. It is commonly characterized by fever, chills, vomiting, anemia, hepatosplenomegaly, leukopenia, hypergammaglobulinemia, emaciation, and an earth-gray color of the skin. The disease is classified into three main types according to geographic distribution: Indian, Mediterranean (or infantile), and African.
Synonyms:exact_synonym: KALA-AZAR, SUSCEPTIBILITY TO, 1;   KALA-AZAR, SUSCEPTIBILITY TO, 2;   KALA-AZAR, SUSCEPTIBILITY TO, 3;   KAZA1;   KAZA2;   KAZA3;   Kala Azar;   black fever;   infection by visceral leishmaniasis;   visceral leishmaniasis, susceptibility to, 1;   visceral leishmaniasis, susceptibility to, 3
 primary_id: MESH:D007898
 alt_id: OMIM:608207;   OMIM:611381;   OMIM:611382;   RDO:0005977
 xref: OMIM:PS608207;   ORDO:507
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visceral leishmaniasis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ccl4 C-C motif chemokine ligand 4 JBrowse link 10 70,870,926 70,886,357 RGD:5683905
G Ccr2 C-C motif chemokine receptor 2 RGD:8661728
G Ccr3 C-C motif chemokine receptor 3 JBrowse link 8 133,026,539 133,040,999 RGD:6893393
G Cd40 CD40 molecule JBrowse link 3 161,519,789 161,534,943 RGD:8547750
G Cd40lg CD40 ligand JBrowse link X 159,703,703 159,714,886 RGD:8547750
G Crp C-reactive protein JBrowse link 13 91,080,448 91,081,358 RGD:11554173
G Csf2 colony stimulating factor 2 JBrowse link 10 39,602,089 39,604,070 RGD:10449527
RGD:11554173
G Hmox1 heme oxygenase 1 JBrowse link 19 14,508,634 14,515,455 RGD:11554173
G Ifng interferon gamma JBrowse link 7 61,337,383 61,341,419 RGD:8158041
RGD:11554173
G Il10 interleukin 10 JBrowse link 13 47,738,933 47,743,392 RGD:11554173
G Il10ra interleukin 10 receptor subunit alpha JBrowse link 8 49,558,062 49,573,891 RGD:11554173
G Il18 interleukin 18 JBrowse link 8 55,009,666 55,016,286 RGD:8655922
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:11554173
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:11554173
G Lta lymphotoxin alpha JBrowse link 20 4,851,889 4,854,677 RGD:8548784
RGD:8548789
G Ltb lymphotoxin beta JBrowse link 20 5,184,631 5,186,476 RGD:8548822
G Mbl2 mannose binding lectin 2 JBrowse link 1 248,435,069 248,442,669 RGD:8693721
RGD:8693726
G RT1-Ba RT1 class II, locus Ba JBrowse link 20 4,066,133 4,070,726 RGD:11554173
G RT1-Db1 RT1 class II, locus Db1 JBrowse link 20 4,087,621 4,097,190 RGD:11554173
G Slc11a1 solute carrier family 11 member 1 JBrowse link 9 81,655,590 81,666,697 RGD:5684944
RGD:11554173
G Stat4 signal transducer and activator of transcription 4 JBrowse link 9 54,340,649 54,457,753 RGD:8661696
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:8548784
RGD:11554173
RGD:8548789

Term paths to the root
Path 1
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  disease 14875
    disease of anatomical entity 14051
      endocrine system disease 4668
        liver disease 2270
          visceral leishmaniasis 22
Path 2
Term Annotations click to browse term
  disease 14875
    disease of anatomical entity 14051
      nervous system disease 9116
        sensory system disease 4246
          skin disease 2253
            Infectious Skin Diseases 137
              Parasitic Skin Diseases 47
                leishmaniasis 43
                  visceral leishmaniasis 22
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.