ONTOLOGY REPORT - ANNOTATIONS


Term:Goodpasture syndrome
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Accession:DOID:9808 term browser browse the term
Definition:An autoimmune hypersensitivity disease that is characterized by antibody attack of the basement membrane in lungs and kidneys, leading to bleeding from the lungs and kidney failure. (DO)
Synonyms:exact_synonym: Goodpasture's syndrome;   Goodpastures syndrome;   Lung Purpura with Nephritis;   anti-GBM disease
 primary_id: OMIM:233450
 alt_id: RDO:9004829
 xref: GARD:2551
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anti-basement membrane glomerulonephritis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Agt angiotensinogen JBrowse link 19 57,321,594 57,333,460 RGD:5129185
RGD:11039051
G Agtr1a angiotensin II receptor, type 1a JBrowse link 17 35,907,102 35,958,136 RGD:5129185
G Bax BCL2 associated X, apoptosis regulator JBrowse link 1 101,451,801 101,457,207 RGD:1579984
G Bcl2 BCL2, apoptosis regulator JBrowse link 13 26,605,426 26,769,374 RGD:1579984
G Ccl17 C-C motif chemokine ligand 17 JBrowse link 19 10,619,220 10,620,671 RGD:4145614
G Ccl2 C-C motif chemokine ligand 2 JBrowse link 10 69,412,065 69,413,863 RGD:2307059
RGD:4145614
RGD:6218988
G Ccl22 C-C motif chemokine ligand 22 JBrowse link 19 10,674,189 10,681,145 RGD:2306306
G Ccl4 C-C motif chemokine ligand 4 JBrowse link 10 70,870,926 70,886,357 RGD:2307059
G Ccl5 C-C motif chemokine ligand 5 JBrowse link 10 70,739,764 70,744,303 RGD:2307059
G Cd274 CD274 molecule JBrowse link 1 247,519,890 247,539,659 RGD:7248671
G Cd40 CD40 molecule JBrowse link 3 161,519,789 161,534,943 RGD:7248442
G Cd40lg CD40 ligand JBrowse link X 159,703,703 159,714,886 RGD:5508170
G Cd80 Cd80 molecule JBrowse link 11 64,815,201 64,855,293 RGD:6902936
G Cfb complement factor B JBrowse link 20 4,536,206 4,542,073 RGD:7242700
G Clu clusterin JBrowse link 15 42,626,612 42,665,858 RGD:9068422
G Csf1 colony stimulating factor 1 JBrowse link 2 210,522,370 210,550,546 RGD:7257569
G Csf1r colony stimulating factor 1 receptor JBrowse link 18 56,414,493 56,458,300 RGD:7257569
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 JBrowse link 9 67,699,397 67,706,068 RGD:6902936
RGD:11352257
G Cx3cl1 C-X3-C motif chemokine ligand 1 JBrowse link 19 10,644,267 10,654,861 RGD:4891946
G Cx3cr1 C-X3-C motif chemokine receptor 1 JBrowse link 8 128,740,756 128,754,514 RGD:4891946
G Cxcl12 C-X-C motif chemokine ligand 12 JBrowse link 4 149,261,044 149,273,891 RGD:2306579
G Dusp1 dual specificity phosphatase 1 JBrowse link 10 16,970,642 16,973,425 RGD:633769
G Fcgr3a Fc fragment of IgG receptor IIIa JBrowse link 13 89,385,775 89,396,047 RGD:5508400
RGD:5508403
G Gp6 glycoprotein VI JBrowse link 1 72,994,977 73,064,639 RGD:7242710
G Il10 interleukin 10 JBrowse link 13 47,738,933 47,743,392 RGD:7365004
G Il17a interleukin 17A JBrowse link 9 26,841,299 26,844,786 RGD:7365004
G Il18 interleukin 18 JBrowse link 8 55,009,666 55,016,286 RGD:6893447
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:6893447
RGD:7401232
G Il1rn interleukin 1 receptor antagonist JBrowse link 3 1,449,778 1,468,624 RGD:4145614
G Il4 interleukin 4 JBrowse link 10 38,963,979 38,969,531 RGD:2317673
RGD:2307059
G Itga4 integrin subunit alpha 4 JBrowse link 3 66,178,745 66,265,547 RGD:2308810
RGD:9698425
G Mapk14 mitogen activated protein kinase 14 JBrowse link 20 5,933,290 5,995,137 RGD:6218988
G Mapk8 mitogen-activated protein kinase 8 JBrowse link 16 9,620,854 9,709,342 RGD:6218988
G Mif macrophage migration inhibitory factor JBrowse link 20 13,715,219 13,732,980 RGD:1642011
G Mmp12 matrix metallopeptidase 12 JBrowse link 8 5,594,717 5,616,494 RGD:6218988
G Mmp14 matrix metallopeptidase 14 JBrowse link 15 33,074,441 33,083,666 RGD:2314954
G Nos2 nitric oxide synthase 2 JBrowse link 10 66,188,290 66,221,621 RGD:6218988
G Nppb natriuretic peptide B JBrowse link 5 164,796,176 164,797,538 RGD:7248605
G Pdcd1 programmed cell death 1 JBrowse link 9 101,305,742 101,319,937 RGD:7248671
G Ppara peroxisome proliferator activated receptor alpha JBrowse link 7 126,618,872 126,687,282 RGD:5563035
G Ptk2b protein tyrosine kinase 2 beta JBrowse link 15 42,827,306 42,947,796 RGD:729912
G Rapgef1 Rap guanine nucleotide exchange factor 1 JBrowse link 3 8,189,594 8,307,077 RGD:11534983
G RT1-Db1 RT1 class II, locus Db1 JBrowse link 20 4,087,621 4,097,190 RGD:5147561
G Selp selectin P JBrowse link 13 82,428,914 82,464,629 RGD:6218988
G Slc34a1 solute carrier family 34 member 1 JBrowse link 17 9,747,766 9,762,739 RGD:7242947
G Slit2 slit guidance ligand 2 JBrowse link 14 66,831,848 67,171,491 RGD:2316132
G Spp1 secreted phosphoprotein 1 JBrowse link 14 6,673,686 6,679,965 RGD:6903276
G Syk spleen associated tyrosine kinase JBrowse link 17 12,614,311 12,669,568 RGD:6218988
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6218988
G Vcam1 vascular cell adhesion molecule 1 JBrowse link 2 219,071,193 219,090,931 RGD:7241232
G Xcl1 X-C motif chemokine ligand 1 JBrowse link 13 83,199,402 83,202,845 RGD:8693304

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 14875
    syndrome 4220
      Goodpasture syndrome 55
        anti-basement membrane glomerulonephritis 55
Path 2
Term Annotations click to browse term
  disease 14875
    disease of anatomical entity 14051
      Immune & Inflammatory Diseases 2988
        immune system disease 2414
          Autoimmune Diseases 1447
            autoimmune hypersensitivity disease 1162
              Goodpasture syndrome 55
                anti-basement membrane glomerulonephritis 55
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.