ONTOLOGY REPORT - ANNOTATIONS


Term:polyarteritis nodosa
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Accession:DOID:9810 term browser browse the term
Definition:A form of necrotizing non-granulomatous inflammation occurring primarily in medium-sized ARTERIES, often with microaneurysms. It is characterized by muscle, joint, and abdominal pain resulting from arterial infarction and scarring in affected organs. Polyarteritis nodosa with lung involvement is called CHURG-STRAUSS SYNDROME.
Synonyms:exact_synonym: Essential Polyarteritides;   Essential Polyarteritis;   Necrotizing Arteritides;   Necrotizing Arteritis;   Periarteritis Nodosa
 primary_id: MESH:D010488;   RDO:0002467
 xref: GARD:7360
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polyarteritis nodosa term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cx3cl1 C-X3-C motif chemokine ligand 1 JBrowse link 19 10,644,267 10,654,861 RGD:9068463
G Eln elastin JBrowse link 12 24,978,478 25,021,864 RGD:9585739
G Fgf2 fibroblast growth factor 2 JBrowse link 2 124,081,072 124,134,133 RGD:8655581
G Gdnf glial cell derived neurotrophic factor JBrowse link 2 56,884,181 56,912,964 RGD:6218983
G Gfra1 GDNF family receptor alpha 1 JBrowse link 1 279,203,046 279,572,789 RGD:6218983
G Vegfa vascular endothelial growth factor A JBrowse link 9 17,340,341 17,355,681 RGD:8655581

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 14875
    sensory system disease 4246
      skin disease 2253
        vascular skin disease 135
          polyarteritis nodosa 6
            Polyarteritis Nodosa, Childhood-Onset 0
            Systemic Necrotizing Angiitis 0
Path 2
Term Annotations click to browse term
  disease 14875
    disease of anatomical entity 14051
      cardiovascular system disease 4056
        vascular disease 3039
          vasculitis 138
            Arteritis 34
              polyarteritis nodosa 6
                Polyarteritis Nodosa, Childhood-Onset 0
                Systemic Necrotizing Angiitis 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.