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Term:eosinophilia-myalgia syndrome
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Accession:DOID:998 term browser browse the term
Definition:A complex systemic syndrome with inflammatory and autoimmune components that affect the skin, fascia, muscle, nerve, blood vessels, lung, and heart. Diagnostic features generally include EOSINOPHILIA, myalgia severe enough to limit usual activities of daily living, and the absence of coexisting infectious, autoimmune or other conditions that may induce eosinophilia. Biopsy of affected tissue reveals a microangiopathy associated with diffuse inflammation involving connective tissue. (From Spitzer et al., J Rheumatol Suppl 1996 Oct;46:73-9; Blackburn WD, Semin Arthritis Rheum 1997 Jun;26(6):788-93)
Synonyms:exact_synonym: Eosinophilia-Myalgia Syndromes;   L-Tryptophan-Related Eosinophilia-Myalgia Syndrome;   L-Tryptophan-Related Eosinophilia-Myalgia Syndromes
 primary_id: MESH:D016603;   RDO:0006980
 xref: GARD:6345
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  disease 10706
    syndrome 4118
      hypereosinophilic syndrome 21
        eosinophilia-myalgia syndrome 0
Path 2
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  disease 10706
    disease of anatomical entity 10215
      nervous system disease 7870
        peripheral nervous system disease 1854
          neuropathy 1694
            neuromuscular disease 1286
              muscular disease 821
                eosinophilia-myalgia syndrome 0
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