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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of DNA recombination
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Accession:GO:0000018 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of DNA recombination, a DNA metabolic process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents.


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regulation of DNA recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ALYREF Aly/REF export factor JBrowse link 17 81,995,578 82,000,836 RGD:9068941
G IL7R interleukin 7 receptor JBrowse link 5 79,769,859 79,792,566 RGD:9068941
G KPNA1 karyopherin subunit alpha 1 JBrowse link 3 126,418,157 126,510,325 RGD:9068941
G KPNA2 karyopherin subunit alpha 2 JBrowse link 17 67,161,908 67,173,410 RGD:9068941
G SMARCAD1 SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 JBrowse link 4 97,240,372 97,324,366 RGD:9068941
G THOC1 THO complex 1 JBrowse link 18 17,692,797 17,742,572 RGD:9068941
negative regulation of DNA recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BLM BLM RecQ like helicase JBrowse link 15 88,607,157 88,707,864 RGD:9068941
G H1-1 H1.1 linker histone, cluster member JBrowse link 6 26,508,422 26,509,202 RGD:9068941
G H1-2 H1.2 linker histone, cluster member JBrowse link 6 26,548,932 26,549,698 RGD:9068941
G H1-3 H1.3 linker histone, cluster member JBrowse link 6 26,729,188 26,729,978 RGD:9068941
G H1-4 H1.4 linker histone, cluster member JBrowse link 6 26,652,095 26,667,063 RGD:9068941
G H1-6 H1.6 linker histone, cluster member JBrowse link 6 26,600,402 26,601,119 RGD:9068941
G LOC100970460 histone H1.0 JBrowse link 22 36,551,246 36,553,595 RGD:9068941
G LOC100983953 histone H1.5 JBrowse link 6 28,368,652 28,372,137 RGD:9068941
G LOC100987154 testis-specific H1 histone JBrowse link 12 41,280,957 41,282,281 RGD:9068941
G LOC100993446 histone H1oo JBrowse link 3 133,952,981 133,961,243 RGD:9068941
G MSH2 mutS homolog 2 JBrowse link 2A 48,447,207 48,525,638 RGD:9068941
G MSH3 mutS homolog 3 JBrowse link 5 34,719,261 34,938,521 RGD:9068941
G MSH6 mutS homolog 6 JBrowse link 2A 48,824,469 48,849,779 RGD:9068941
G RTEL1 regulator of telomere elongation helicase 1 JBrowse link 20 61,580,222 61,619,172 RGD:9068941
G ZRANB3 zinc finger RANBP2-type containing 3 JBrowse link 2B 139,271,306 139,603,946 RGD:9068941
negative regulation of DNA recombination at telomere term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G TERF2IP TERF2 interacting protein JBrowse link 16 75,565,090 75,574,701 RGD:9068941
negative regulation of double-strand break repair via homologous recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CGAS cyclic GMP-AMP synthase JBrowse link 6 74,542,994 74,567,107 RGD:9068941
G FANCB FA complementation group B JBrowse link X 14,752,929 14,785,847 RGD:9068941
G FBH1 F-box DNA helicase 1 JBrowse link 10 5,915,696 5,962,778 RGD:9068941
G HELB DNA helicase B JBrowse link 12 23,078,732 23,114,134 RGD:9068941
G KLHL15 kelch like family member 15 JBrowse link X 23,956,827 23,997,742 RGD:9068941
G MAD2L2 mitotic arrest deficient 2 like 2 JBrowse link 1 11,654,963 11,671,364 RGD:9068941
G MAGEF1 MAGE family member F1 JBrowse link 3 190,229,331 190,231,092 RGD:9068941
G PARPBP PARP1 binding protein JBrowse link 12 103,105,104 103,182,366 RGD:9068941
G POLQ DNA polymerase theta JBrowse link 3 125,446,829 125,558,642 RGD:9068941
G RADX RPA1 related single stranded DNA binding protein, X-linked JBrowse link X 106,092,394 106,159,716 RGD:9068941
G RECQL5 RecQ like helicase 5 JBrowse link 17 75,128,325 75,168,254 RGD:9068941
G RIF1 replication timing regulatory factor 1 JBrowse link 2B 155,985,960 156,109,726 RGD:9068941
G RMI2 RecQ mediated genome instability 2 JBrowse link 16 11,507,406 11,513,561 RGD:9068941
G SHLD1 shieldin complex subunit 1 JBrowse link 20 5,537,989 5,642,107 RGD:9068941
G SHLD2 shieldin complex subunit 2 JBrowse link 14 87,923,049 87,928,101 RGD:9068941
G SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1 JBrowse link 18 13,785,912 13,933,889 RGD:9068941
G TP53BP1 tumor protein p53 binding protein 1 JBrowse link 15 40,519,012 40,626,845 RGD:9068941
G UBQLN4 ubiquilin 4 JBrowse link 1 135,209,490 135,225,666 RGD:9068941
negative regulation of isotype switching term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PARP3 poly(ADP-ribose) polymerase family member 3 JBrowse link 3 53,112,494 53,119,053 RGD:9068941
negative regulation of isotype switching to IgA isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G THOC1 THO complex 1 JBrowse link 18 17,692,797 17,742,572 RGD:9068941
negative regulation of isotype switching to IgE isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BCL6 BCL6 transcription repressor JBrowse link 3 193,308,296 193,332,452 RGD:9068941
G FOXP3 forkhead box P3 JBrowse link X 49,402,652 49,417,029 RGD:9068941
G NDFIP1 Nedd4 family interacting protein 1 JBrowse link 5 143,596,345 143,622,913 RGD:9068941
negative regulation of mitotic recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G MLH1 mutL homolog 1 JBrowse link 3 37,189,439 37,245,801 RGD:9068941
G ZSCAN4 zinc finger and SCAN domain containing 4 JBrowse link 19 63,510,203 63,520,452 RGD:9068941
negative regulation of telomere maintenance via recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G TERF2 telomeric repeat binding factor 2 JBrowse link 16 69,115,208 69,148,175 RGD:9068941
positive regulation of double-strand break repair via homologous recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ACTR2 actin related protein 2 JBrowse link 2A 66,412,786 66,456,857 RGD:9068941
G ARID2 AT-rich interaction domain 2 JBrowse link 12 43,692,717 43,871,652 RGD:9068941
G ERCC6 ERCC excision repair 6, chromatin remodeling factor RGD:9068941
G FANCB FA complementation group B JBrowse link X 14,752,929 14,785,847 RGD:9068941
G FUS FUS RNA binding protein JBrowse link 16 31,551,035 31,562,494 RGD:9068941
G MMS19 MMS19 homolog, cytosolic iron-sulfur assembly component JBrowse link 10 97,574,257 97,613,964 RGD:9068941
G MRNIP MRN complex interacting protein JBrowse link 5 182,299,111 182,340,717 RGD:9068941
G PARP1 poly(ADP-ribose) polymerase 1 JBrowse link 1 206,812,981 206,860,356 RGD:9068941
G TIMELESS timeless circadian regulator JBrowse link 12 32,718,649 32,750,728 RGD:9068941
G WAS WASP actin nucleation promoting factor JBrowse link X 48,842,765 48,850,380 RGD:9068941
G WRAP53 WD repeat containing antisense to TP53 JBrowse link 17 7,707,220 7,723,410 RGD:9068941
positive regulation of interleukin-4-dependent isotype switching to IgE isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G TNFSF4 TNF superfamily member 4 JBrowse link 1 152,391,450 152,699,026 RGD:9068941
positive regulation of isotype switching term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G EXOSC3 exosome component 3 JBrowse link 9 38,552,659 38,558,075 RGD:9068941
G EXOSC6 exosome component 6 JBrowse link 7 152,645,545 152,657,307 RGD:9068941
G HMCES 5-hydroxymethylcytosine binding, ES cell specific JBrowse link 3 133,694,676 133,721,519 RGD:9068941
G KMT5B lysine methyltransferase 5B JBrowse link 11 66,546,398 66,581,553 RGD:9068941
G KMT5C lysine methyltransferase 5C JBrowse link 19 61,073,185 61,079,389 RGD:9068941
G MAD2L2 mitotic arrest deficient 2 like 2 JBrowse link 1 11,654,963 11,671,364 RGD:9068941
G PAXIP1 PAX interacting protein 1 JBrowse link 7 158,274,193 158,329,139 RGD:9068941
G RIF1 replication timing regulatory factor 1 JBrowse link 2B 155,985,960 156,109,726 RGD:9068941
G SHLD1 shieldin complex subunit 1 JBrowse link 20 5,537,989 5,642,107 RGD:9068941
G SHLD2 shieldin complex subunit 2 JBrowse link 14 87,923,049 87,928,101 RGD:9068941
G TFRC transferrin receptor JBrowse link 3 203,333,953 203,365,586 RGD:9068941
G TP53BP1 tumor protein p53 binding protein 1 JBrowse link 15 40,519,012 40,626,845 RGD:9068941
positive regulation of isotype switching to IgA isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G MLH1 mutL homolog 1 JBrowse link 3 37,189,439 37,245,801 RGD:9068941
G MSH2 mutS homolog 2 JBrowse link 2A 48,447,207 48,525,638 RGD:9068941
G NSD2 nuclear receptor binding SET domain protein 2 JBrowse link 4 1,938,777 2,027,425 RGD:9068941
G TGFB1 transforming growth factor beta 1 JBrowse link 19 46,831,659 46,852,973 RGD:9068941
G TNFSF13 TNF superfamily member 13 JBrowse link 17 7,576,518 7,579,834 RGD:9068941
positive regulation of isotype switching to IgE isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CLCF1 cardiotrophin like cytokine factor 1 JBrowse link 11 66,034,536 66,042,114 RGD:9068941
G IL4 interleukin 4 JBrowse link 5 134,253,039 134,261,581 RGD:9068941
G STAT6 signal transducer and activator of transcription 6 JBrowse link 12 32,068,645 32,085,099 RGD:9068941
positive regulation of isotype switching to IgG isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ATAD5 ATPase family AAA domain containing 5 JBrowse link 17 25,435,787 25,496,752 RGD:9068941
G CD28 CD28 molecule JBrowse link 2B 209,076,388 209,111,213 RGD:9068941
G CD40 CD40 molecule JBrowse link 20 43,541,619 43,552,994 RGD:9068941
G IL2 interleukin 2 JBrowse link 4 125,782,563 125,787,819 RGD:9068941
G IL4 interleukin 4 JBrowse link 5 134,253,039 134,261,581 RGD:9068941
G MLH1 mutL homolog 1 JBrowse link 3 37,189,439 37,245,801 RGD:9068941
G MSH2 mutS homolog 2 JBrowse link 2A 48,447,207 48,525,638 RGD:9068941
G PAXIP1 PAX interacting protein 1 JBrowse link 7 158,274,193 158,329,139 RGD:9068941
G PTPRC protein tyrosine phosphatase receptor type C JBrowse link 1 178,555,803 178,674,089 RGD:9068941
G TBX21 T-box transcription factor 21 JBrowse link 17 9,973,343 9,988,131 RGD:9068941
positive regulation of mitotic recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ERCC2 ERCC excision repair 2, TFIIH core complex helicase subunit JBrowse link 19 50,897,004 50,915,849 RGD:9068941
positive regulation of reciprocal meiotic recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PRDM9 PR/SET domain 9 JBrowse link 5 92,377,523 92,395,930 RGD:9068941
G UBE2B ubiquitin conjugating enzyme E2 B JBrowse link 5 135,925,217 135,944,609 RGD:9068941
positive regulation of strand invasion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G WRN WRN RecQ like helicase JBrowse link 8 27,541,145 27,679,855 RGD:9068941
regulation of double-strand break repair via homologous recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CHEK1 checkpoint kinase 1 JBrowse link 11 124,359,218 124,410,385 RGD:9068941
G FIGN fidgetin, microtubule severing factor JBrowse link 2B 168,259,440 168,387,036 RGD:9068941
G FIGNL1 fidgetin like 1 JBrowse link 7 51,330,922 51,337,201 RGD:9068941
G FIGNL2 fidgetin like 2 JBrowse link 12 37,698,429 37,718,699 RGD:9068941
G KDM1A lysine demethylase 1A JBrowse link 1 23,153,066 23,217,693 RGD:9068941
G PPP4C protein phosphatase 4 catalytic subunit JBrowse link 16 30,450,550 30,459,889 RGD:9068941
G PPP4R2 protein phosphatase 4 regulatory subunit 2 JBrowse link 3 74,863,935 74,935,446 RGD:9068941
G RAD51 RAD51 recombinase JBrowse link 15 37,891,061 37,925,207 RGD:9068941
G RAD51AP1 RAD51 associated protein 1 JBrowse link 12 4,578,621 4,599,879 RGD:9068941
G RPA2 replication protein A2 JBrowse link 1 28,191,726 28,214,665 RGD:9068941
G RTEL1 regulator of telomere elongation helicase 1 JBrowse link 20 61,580,222 61,619,172 RGD:9068941
G SETD2 SET domain containing 2, histone lysine methyltransferase JBrowse link 3 48,017,856 48,164,007 RGD:9068941
G SIRT6 sirtuin 6 JBrowse link 19 4,146,057 4,154,132 RGD:9068941
G SPIDR scaffold protein involved in DNA repair JBrowse link 8 41,083,934 41,559,683 RGD:9068941
G TERF2IP TERF2 interacting protein JBrowse link 16 75,565,090 75,574,701 RGD:9068941
G TEX15 testis expressed 15, meiosis and synapsis associated JBrowse link 8 27,334,129 27,421,154 RGD:9068941
G USP51 ubiquitin specific peptidase 51 RGD:9068941
G ZNF365 zinc finger protein 365 JBrowse link 10 61,223,925 61,329,657 RGD:9068941
regulation of isotype switching term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G APLF aprataxin and PNKP like factor JBrowse link 2A 69,632,459 69,744,611 RGD:9068941
G IL10 interleukin 10 JBrowse link 1 186,648,289 186,653,155 RGD:9068941
G IL4 interleukin 4 JBrowse link 5 134,253,039 134,261,581 RGD:9068941
G SUPT6H SPT6 homolog, histone chaperone and transcription elongation factor JBrowse link 17 28,578,199 28,617,347 RGD:9068941
regulation of isotype switching to IgG isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G FOXP3 forkhead box P3 JBrowse link X 49,402,652 49,417,029 RGD:9068941
G IL27RA interleukin 27 receptor subunit alpha JBrowse link 19 14,323,618 14,343,636 RGD:9068941
G NDFIP1 Nedd4 family interacting protein 1 JBrowse link 5 143,596,345 143,622,913 RGD:9068941
regulation of mitotic recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ERCC2 ERCC excision repair 2, TFIIH core complex helicase subunit JBrowse link 19 50,897,004 50,915,849 RGD:9068941
G MRE11 MRE11 homolog, double strand break repair nuclease JBrowse link 11 92,908,403 92,985,966 RGD:9068941
G RAD50 RAD50 double strand break repair protein JBrowse link 5 134,134,506 134,222,261 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15702
    metabolic process 10531
      regulation of metabolic process 6285
        regulation of macromolecule metabolic process 5754
          regulation of DNA metabolic process 356
            regulation of DNA recombination 103
              negative regulation of DNA recombination + 42
              positive regulation of DNA recombination + 42
              regulation of DNA recombination at centromere + 0
              regulation of DNA recombination at telomere + 2
              regulation of double-strand break repair via homologous recombination + 46
              regulation of isotype switching + 36
              regulation of mitotic recombination + 6
              regulation of reciprocal meiotic recombination + 2
              regulation of single-strand break repair via homologous recombination + 0
              regulation of strand invasion + 1
              regulation of transposition, DNA-mediated + 0
Path 2
Term Annotations click to browse term
  biological_process 15702
    metabolic process 10531
      cellular metabolic process 9895
        cellular aromatic compound metabolic process 5427
          nucleobase-containing compound metabolic process 5229
            nucleic acid metabolic process 4725
              DNA metabolic process 905
                regulation of DNA metabolic process 356
                  regulation of DNA recombination 103
                    negative regulation of DNA recombination + 42
                    positive regulation of DNA recombination + 42
                    regulation of DNA recombination at centromere + 0
                    regulation of DNA recombination at telomere + 2
                    regulation of double-strand break repair via homologous recombination + 46
                    regulation of isotype switching + 36
                    regulation of mitotic recombination + 6
                    regulation of reciprocal meiotic recombination + 2
                    regulation of single-strand break repair via homologous recombination + 0
                    regulation of strand invasion + 1
                    regulation of transposition, DNA-mediated + 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.