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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of DNA recombination
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Accession:GO:0000018 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of DNA recombination, a DNA metabolic process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents.


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regulation of DNA recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G SMARCAD1 SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 JBrowse link 32 17,089,514 17,167,917 RGD:13508589
negative regulation of DNA recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BLM BLM RecQ like helicase JBrowse link 3 53,408,120 53,506,728 RGD:13508589
G H1-2 H1.2 linker histone, cluster member JBrowse link 35 24,009,304 24,011,602 RGD:13508589
G H1-6 H1.6 linker histone, cluster member JBrowse link 35 24,046,374 24,065,892 RGD:13508589
G H1-7 H1.7 linker histone JBrowse link 27 6,389,797 6,396,021 RGD:13508589
G H1-8 H1.8 linker histone JBrowse link 20 5,614,822 5,619,136 RGD:13508589
G LOC488269 histone H1.4 RGD:13508589
G MSH2 mutS homolog 2 JBrowse link 10 49,517,448 49,594,001 RGD:13508589
G MSH3 mutS homolog 3 JBrowse link 3 26,335,788 26,520,633 RGD:13508589
G MSH6 mutS homolog 6 JBrowse link 10 49,825,330 49,838,036 RGD:13508589
G RTEL1 regulator of telomere elongation helicase 1 JBrowse link 24 47,219,977 47,248,791 RGD:13508589
negative regulation of DNA recombination at telomere term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G TERF2IP TERF2 interacting protein JBrowse link 5 75,164,410 75,172,959 RGD:13508589
negative regulation of double-strand break repair via homologous recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CGAS cyclic GMP-AMP synthase JBrowse link 12 35,511,920 35,528,759 RGD:13508589
G FANCB FA complementation group B JBrowse link X 10,690,826 11,140,838 RGD:13508589
G FBH1 F-box DNA helicase 1 JBrowse link 2 30,047,994 30,095,761 RGD:13508589
G HELB DNA helicase B JBrowse link 10 8,766,023 8,797,055 RGD:13508589
G KLHL15 kelch like family member 15 JBrowse link X 19,617,629 19,651,076 RGD:13508589
G MAD2L2 mitotic arrest deficient 2 like 2 JBrowse link 2 84,539,724 84,549,402 RGD:13508589
G MAGEF1 MAGE family member F1 JBrowse link 34 17,543,381 17,545,089 RGD:13508589
G PARPBP PARP1 binding protein JBrowse link 15 40,972,098 41,039,044 RGD:13508589
G POLQ DNA polymerase theta JBrowse link 33 24,713,174 24,837,113 RGD:13508589
G RADX RPA1 related single stranded DNA binding protein, X-linked JBrowse link X 80,146,335 80,234,732 RGD:13508589
G RECQL5 RecQ like helicase 5 JBrowse link 9 4,902,753 4,940,442 RGD:13508589
G RIF1 replication timing regulatory factor 1 JBrowse link 19 52,661,278 52,711,969 RGD:13508589
G RMI2 RecQ mediated genome instability 2 JBrowse link 6 31,440,493 31,445,318 RGD:13508589
G SHLD1 shieldin complex subunit 1 JBrowse link 24 15,957,863 16,037,336 RGD:13508589
G TP53BP1 tumor protein p53 binding protein 1 JBrowse link 30 10,263,650 10,362,646 RGD:13508589
G UBQLN4 ubiquilin 4 JBrowse link 7 41,764,209 41,778,457 RGD:13508589
negative regulation of isotype switching term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PARP3 poly(ADP-ribose) polymerase family member 3 JBrowse link 20 37,767,336 37,774,269 RGD:13508589
negative regulation of isotype switching to IgA isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G THOC1 THO complex 1 JBrowse link 7 67,082,100 67,136,592 RGD:13508589
negative regulation of isotype switching to IgE isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BCL6 BCL6 transcription repressor JBrowse link 34 20,112,302 20,135,705 RGD:13508589
negative regulation of mitotic recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G MLH1 mutL homolog 1 JBrowse link 23 6,889,108 6,938,117 RGD:13508589
negative regulation of telomere maintenance via recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G TERF2 telomeric repeat binding factor 2 JBrowse link 5 80,278,224 80,305,315 RGD:13508589
positive regulation of double-strand break repair via homologous recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ERCC6 ERCC excision repair 6, chromatin remodeling factor JBrowse link 28 1,358,383 1,432,276 RGD:13508589
G FANCB FA complementation group B JBrowse link X 10,690,826 11,140,838 RGD:13508589
G FUS FUS RNA binding protein JBrowse link 6 17,059,904 17,071,227 RGD:13508589
G MMS19 MMS19 homolog, cytosolic iron-sulfur assembly component JBrowse link 28 10,749,327 10,783,846 RGD:13508589
G PARP1 poly(ADP-ribose) polymerase 1 JBrowse link 7 38,503,072 38,542,556 RGD:13508589
G TIMELESS timeless circadian regulator JBrowse link 10 671,829 701,152 RGD:13508589
positive regulation of isotype switching term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G EXOSC3 exosome component 3 JBrowse link 11 54,072,993 54,079,024 RGD:13508589
G HMCES 5-hydroxymethylcytosine binding, ES cell specific JBrowse link 20 2,808,687 2,831,123 RGD:13508589
G KMT5B lysine methyltransferase 5B JBrowse link 18 49,655,783 49,691,899 RGD:13508589
G KMT5C lysine methyltransferase 5C JBrowse link 1 102,334,687 102,342,090 RGD:13508589
G MAD2L2 mitotic arrest deficient 2 like 2 JBrowse link 2 84,539,724 84,549,402 RGD:13508589
G RIF1 replication timing regulatory factor 1 JBrowse link 19 52,661,278 52,711,969 RGD:13508589
G SHLD1 shieldin complex subunit 1 JBrowse link 24 15,957,863 16,037,336 RGD:13508589
G TFRC transferrin receptor JBrowse link 33 29,206,024 29,237,221 RGD:13508589
G TP53BP1 tumor protein p53 binding protein 1 JBrowse link 30 10,263,650 10,362,646 RGD:13508589
positive regulation of isotype switching to IgA isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G B9D2 B9 domain containing 2 JBrowse link 1 112,621,832 112,627,726 RGD:13508589
G MLH1 mutL homolog 1 JBrowse link 23 6,889,108 6,938,117 RGD:13508589
G MSH2 mutS homolog 2 JBrowse link 10 49,517,448 49,594,001 RGD:13508589
G NSD2 nuclear receptor binding SET domain protein 2 JBrowse link 3 62,164,888 62,228,006 RGD:13508589
G TGFB1 transforming growth factor beta 1 JBrowse link 1 112,629,476 112,643,885 RGD:13508589
positive regulation of isotype switching to IgE isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G IL4 interleukin 4 JBrowse link 11 20,972,693 20,981,539 RGD:13508589
positive regulation of isotype switching to IgG isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ATAD5 ATPase family AAA domain containing 5 JBrowse link 9 40,869,778 40,917,976 RGD:13508589
G IL2 interleukin 2 JBrowse link 19 17,750,780 17,756,394 RGD:13508589
G IL4 interleukin 4 JBrowse link 11 20,972,693 20,981,539 RGD:13508589
G MLH1 mutL homolog 1 JBrowse link 23 6,889,108 6,938,117 RGD:13508589
G MSH2 mutS homolog 2 JBrowse link 10 49,517,448 49,594,001 RGD:13508589
G PAXIP1 PAX interacting protein 1 JBrowse link 16 18,066,289 18,116,007 RGD:13508589
G TBX21 T-box transcription factor 21 JBrowse link 9 24,077,752 24,086,560 RGD:13508589
positive regulation of mitotic recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ERCC2 ERCC excision repair 2, TFIIH core complex helicase subunit JBrowse link 1 110,173,781 110,191,612 RGD:13508589
positive regulation of strand invasion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G WRN WRN RecQ like helicase JBrowse link 16 33,164,662 33,304,466 RGD:13508589
regulation of double-strand break repair via homologous recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G FIGN fidgetin, microtubule severing factor JBrowse link 36 8,914,023 9,045,240 RGD:13508589
G FIGNL1 fidgetin like 1 JBrowse link 18 1,788,063 1,792,900 RGD:13508589
G PPP4C protein phosphatase 4 catalytic subunit JBrowse link 6 18,085,048 18,092,861 RGD:13508589
G PPP4R2 protein phosphatase 4 regulatory subunit 2 JBrowse link 20 19,116,122 19,166,927 RGD:13508589
G RAD51 RAD51 recombinase JBrowse link 30 7,842,540 7,877,128 RGD:13508589
G RAD51AP1 RAD51 associated protein 1 JBrowse link 27 40,303,935 40,341,666 RGD:13508589
G RTEL1 regulator of telomere elongation helicase 1 JBrowse link 24 47,219,977 47,248,791 RGD:13508589
G SETD2 SET domain containing 2, histone lysine methyltransferase JBrowse link 20 41,675,539 41,800,697 RGD:13508589
G SIRT6 sirtuin 6 JBrowse link 20 55,412,989 55,424,944 RGD:13508589
G SPIDR scaffold protein involved in DNA repair JBrowse link 35 79,188 503,687 RGD:13508589
G TERF2IP TERF2 interacting protein JBrowse link 5 75,164,410 75,172,959 RGD:13508589
G TEX15 testis expressed 15, meiosis and synapsis associated JBrowse link 16 33,423,546 33,517,458 RGD:13508589
G ZNF365 zinc finger protein 365 JBrowse link 4 14,297,652 14,429,634 RGD:13508589
regulation of isotype switching term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G APLF aprataxin and PNKP like factor JBrowse link 10 67,454,500 67,522,659 RGD:13508589
G SUPT6H SPT6 homolog, histone chaperone and transcription elongation factor JBrowse link 9 42,859,154 42,896,044 RGD:13508589
regulation of mitotic recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ERCC2 ERCC excision repair 2, TFIIH core complex helicase subunit JBrowse link 1 110,173,781 110,191,612 RGD:13508589

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 14250
    metabolic process 8827
      regulation of metabolic process 4560
        regulation of macromolecule metabolic process 4243
          regulation of DNA metabolic process 219
            regulation of DNA recombination 66
              negative regulation of DNA recombination + 32
              positive regulation of DNA recombination + 27
              regulation of DNA recombination at centromere + 0
              regulation of DNA recombination at telomere + 2
              regulation of double-strand break repair via homologous recombination + 34
              regulation of isotype switching + 24
              regulation of mitotic recombination + 3
              regulation of reciprocal meiotic recombination + 0
              regulation of single-strand break repair via homologous recombination + 0
              regulation of strand invasion + 1
              regulation of transposition, DNA-mediated + 0
Path 2
Term Annotations click to browse term
  biological_process 14250
    metabolic process 8827
      cellular metabolic process 8047
        cellular aromatic compound metabolic process 4166
          nucleobase-containing compound metabolic process 4029
            nucleic acid metabolic process 3646
              DNA metabolic process 615
                regulation of DNA metabolic process 219
                  regulation of DNA recombination 66
                    negative regulation of DNA recombination + 32
                    positive regulation of DNA recombination + 27
                    regulation of DNA recombination at centromere + 0
                    regulation of DNA recombination at telomere + 2
                    regulation of double-strand break repair via homologous recombination + 34
                    regulation of isotype switching + 24
                    regulation of mitotic recombination + 3
                    regulation of reciprocal meiotic recombination + 0
                    regulation of single-strand break repair via homologous recombination + 0
                    regulation of strand invasion + 1
                    regulation of transposition, DNA-mediated + 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.