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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of DNA recombination
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Accession:GO:0000018 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of DNA recombination, a DNA metabolic process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents.


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regulation of DNA recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ALYREF Aly/REF export factor JBrowse link 17 81,887,835 81,891,587 RGD:2290271
G IL7R interleukin 7 receptor JBrowse link 5 35,856,891 35,879,603 RGD:2290271
G KPNA1 karyopherin subunit alpha 1 JBrowse link 3 122,421,902 122,514,939 RGD:2290271
G KPNA2 karyopherin subunit alpha 2 JBrowse link 17 68,035,735 68,046,859 RGD:2290271
G SMARCAD1 SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 JBrowse link 4 94,207,608 94,291,292 RGD:2290271
G THOC1 THO complex 1 JBrowse link 18 214,348 268,047 RGD:2290271
negative regulation of DNA recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BLM BLM RecQ like helicase JBrowse link 15 90,717,346 90,816,166 RGD:2290271
G H1-0 H1.0 linker histone JBrowse link 22 37,805,229 37,807,432 RGD:2290271
G H1-1 H1.1 linker histone, cluster member JBrowse link 6 26,017,032 26,017,787 RGD:2290271
G H1-10 H1.10 linker histone JBrowse link 3 129,314,771 129,316,286 RGD:2290271
G H1-2 H1.2 linker histone, cluster member JBrowse link 6 26,055,740 26,056,470 RGD:2290271
G H1-3 H1.3 linker histone, cluster member JBrowse link 6 26,234,212 26,234,987 RGD:2290271
G H1-4 H1.4 linker histone, cluster member JBrowse link 6 26,156,329 26,157,115 RGD:2290271
G H1-5 H1.5 linker histone, cluster member JBrowse link 6 27,866,792 27,867,588 RGD:2290271
G H1-6 H1.6 linker histone, cluster member JBrowse link 6 26,107,412 26,108,135 RGD:2290271
G H1-7 H1.7 linker histone JBrowse link 12 48,328,980 48,330,279 RGD:2290271
G H1-8 H1.8 linker histone JBrowse link 3 129,543,175 129,555,185 RGD:2290271
G H1-9P H1.9 linker histone, pseudogene JBrowse link 17 50,171,428 50,172,476 RGD:2290271
G MSH2 mutS homolog 2 JBrowse link 2 47,403,067 47,634,501 RGD:2290271
G MSH3 mutS homolog 3 JBrowse link 5 80,654,652 80,876,815 RGD:2290271
G MSH6 mutS homolog 6 JBrowse link 2 47,783,082 47,806,954 RGD:2290271
G RTEL1 regulator of telomere elongation helicase 1 JBrowse link 20 63,657,810 63,696,253 RGD:2290271
G ZRANB3 zinc finger RANBP2-type containing 3 JBrowse link 2 135,164,218 135,531,218 RGD:2290271
negative regulation of DNA recombination at telomere term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G TERF2IP TERF2 interacting protein JBrowse link 16 75,647,737 75,657,442 RGD:2290271
negative regulation of double-strand break repair via homologous recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CGAS cyclic GMP-AMP synthase JBrowse link 6 73,423,711 73,452,297 RGD:2290271
G FANCB FA complementation group B JBrowse link X 14,690,863 14,873,255 RGD:2290271
G FBH1 F-box DNA helicase 1 JBrowse link 10 5,889,572 5,937,595 RGD:2290271
G HELB DNA helicase B JBrowse link 12 66,302,493 66,343,643 RGD:2290271
G KLHL15 kelch like family member 15 JBrowse link X 23,983,720 24,027,186 RGD:2290271
G MAD2L2 mitotic arrest deficient 2 like 2 JBrowse link 1 11,674,480 11,691,621 RGD:2290271
G MAGEF1 MAGE family member F1 JBrowse link 3 184,710,364 184,712,064 RGD:2290271
G PARPBP PARP1 binding protein JBrowse link 12 102,120,171 102,197,520 RGD:2290271
G POLQ DNA polymerase theta JBrowse link 3 121,431,431 121,545,988 RGD:2290271
G RADX RPA1 related single stranded DNA binding protein, X-linked JBrowse link X 106,611,930 106,679,443 RGD:2290271
G RECQL5 RecQ like helicase 5 JBrowse link 17 75,626,845 75,667,202 RGD:2290271
G RIF1 replication timing regulatory factor 1 JBrowse link 2 151,409,902 151,534,200 RGD:2290271
G RMI2 RecQ mediated genome instability 2 JBrowse link 16 11,345,438 11,351,763 RGD:2290271
G SHLD1 shieldin complex subunit 1 JBrowse link 20 5,750,286 5,864,407 RGD:2290271
G SHLD2 shieldin complex subunit 2 JBrowse link 10 87,094,478 87,191,468 RGD:2290271
G SHLD3 shieldin complex subunit 3 JBrowse link 5 65,625,027 65,630,928 RGD:2290271
G SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1 JBrowse link 18 2,655,726 2,805,017 RGD:2290271
G TP53BP1 tumor protein p53 binding protein 1 JBrowse link 15 43,403,061 43,510,640 RGD:2290271
G UBQLN4 ubiquilin 4 JBrowse link 1 156,033,129 156,053,798 RGD:2290271
negative regulation of isotype switching term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PARP3 poly(ADP-ribose) polymerase family member 3 JBrowse link 3 51,942,290 51,948,867 RGD:2290271
negative regulation of isotype switching to IgA isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G THOC1 THO complex 1 JBrowse link 18 214,348 268,047 RGD:2290271
negative regulation of isotype switching to IgE isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BCL6 BCL6 transcription repressor JBrowse link 3 187,721,377 187,745,472 RGD:2290271
G FOXP3 forkhead box P3 JBrowse link X 49,250,436 49,264,932 RGD:2290271
G NDFIP1 Nedd4 family interacting protein 1 JBrowse link 5 142,108,779 142,154,440 RGD:2290271
negative regulation of mitotic recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G MLH1 mutL homolog 1 JBrowse link 3 36,993,350 37,050,846 RGD:2290271
G ZSCAN4 zinc finger and SCAN domain containing 4 JBrowse link 19 57,651,497 57,679,152 RGD:2290271
negative regulation of telomere maintenance via recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G TERF2 telomeric repeat binding factor 2 JBrowse link 16 69,355,567 69,386,007 RGD:2290271
positive regulation of double-strand break repair via homologous recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ACTR2 actin related protein 2 JBrowse link 2 65,227,695 65,271,253 RGD:2290271
G ARID2 AT-rich interaction domain 2 JBrowse link 12 45,729,706 45,908,037 RGD:2290271
G ERCC6 ERCC excision repair 6, chromatin remodeling factor JBrowse link 10 49,454,470 49,539,538 RGD:2290271
G FANCB FA complementation group B JBrowse link X 14,690,863 14,873,255 RGD:2290271
G FUS FUS RNA binding protein JBrowse link 16 31,180,110 31,194,871 RGD:2290271
G MMS19 MMS19 homolog, cytosolic iron-sulfur assembly component JBrowse link 10 97,458,324 97,498,794 RGD:2290271
G MRNIP MRN complex interacting protein JBrowse link 5 179,837,276 179,858,817 RGD:2290271
G PARP1 poly(ADP-ribose) polymerase 1 JBrowse link 1 226,360,691 226,408,093 RGD:2290271
G TIMELESS timeless circadian regulator JBrowse link 12 56,416,363 56,449,426 RGD:2290271
G WAS WASP actin nucleation promoting factor JBrowse link X 48,683,753 48,691,427 RGD:2290271
G WRAP53 WD repeat containing antisense to TP53 JBrowse link 17 7,686,071 7,703,502 RGD:2290271
positive regulation of interleukin-4-dependent isotype switching to IgE isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G TNFSF4 TNF superfamily member 4 JBrowse link 1 173,183,729 173,462,208 RGD:2290271
positive regulation of isotype switching term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G EXOSC3 exosome component 3 JBrowse link 9 37,779,714 37,785,092 RGD:2290271
G EXOSC6 exosome component 6 JBrowse link 16 70,246,778 70,251,940 RGD:2290271
G HMCES 5-hydroxymethylcytosine binding, ES cell specific JBrowse link 3 129,278,832 129,306,186 RGD:2290271
G KMT5B lysine methyltransferase 5B JBrowse link 11 68,154,863 68,213,899 RGD:2290271
G KMT5C lysine methyltransferase 5C JBrowse link 19 55,339,876 55,348,121 RGD:2290271
G MAD2L2 mitotic arrest deficient 2 like 2 JBrowse link 1 11,674,480 11,691,621 RGD:2290271
G PAXIP1 PAX interacting protein 1 JBrowse link 7 154,943,690 155,003,419 RGD:2290271
G RIF1 replication timing regulatory factor 1 JBrowse link 2 151,409,902 151,534,200 RGD:2290271
G SHLD1 shieldin complex subunit 1 JBrowse link 20 5,750,286 5,864,407 RGD:2290271
G SHLD2 shieldin complex subunit 2 JBrowse link 10 87,094,478 87,191,468 RGD:2290271
G SHLD3 shieldin complex subunit 3 JBrowse link 5 65,625,027 65,630,928 RGD:2290271
G TFRC transferrin receptor JBrowse link 3 196,018,694 196,082,123 RGD:2290271
G TP53BP1 tumor protein p53 binding protein 1 JBrowse link 15 43,403,061 43,510,640 RGD:2290271
positive regulation of isotype switching to IgA isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G MLH1 mutL homolog 1 JBrowse link 3 36,993,350 37,050,846 RGD:2290271
G MSH2 mutS homolog 2 JBrowse link 2 47,403,067 47,634,501 RGD:2290271
G NSD2 nuclear receptor binding SET domain protein 2 JBrowse link 4 1,871,393 1,982,207 RGD:2290271
G TGFB1 transforming growth factor beta 1 JBrowse link 19 41,330,323 41,353,922 RGD:2290271
G TNFSF13 TNF superfamily member 13 JBrowse link 17 7,558,292 7,561,608 RGD:2290271
positive regulation of isotype switching to IgE isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CLCF1 cardiotrophin like cytokine factor 1 JBrowse link 11 67,364,168 67,374,177 RGD:2290271
G IL4 interleukin 4 JBrowse link 5 132,673,986 132,682,678 RGD:2290271
G STAT6 signal transducer and activator of transcription 6 JBrowse link 12 57,095,408 57,111,413 RGD:2290271
positive regulation of isotype switching to IgG isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ATAD5 ATPase family AAA domain containing 5 JBrowse link 17 30,830,830 30,895,869 RGD:2290271
G CD28 CD28 molecule JBrowse link 2 203,706,475 203,739,756 RGD:2290271
G CD40 CD40 molecule JBrowse link 20 46,118,242 46,129,858 RGD:2290271
G IL2 interleukin 2 JBrowse link 4 122,449,479 122,456,725 RGD:2290271
G IL4 interleukin 4 JBrowse link 5 132,673,986 132,682,678 RGD:2290271
G MLH1 mutL homolog 1 JBrowse link 3 36,993,350 37,050,846 RGD:2290271
G MSH2 mutS homolog 2 JBrowse link 2 47,403,067 47,634,501 RGD:2290271
G PAXIP1 PAX interacting protein 1 JBrowse link 7 154,943,690 155,003,419 RGD:2290271
G PTPRC protein tyrosine phosphatase receptor type C JBrowse link 1 198,638,968 198,757,476 RGD:2290271
G TBX21 T-box transcription factor 21 JBrowse link 17 47,733,236 47,746,122 RGD:2290271
positive regulation of mitotic recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ERCC2 ERCC excision repair 2, TFIIH core complex helicase subunit JBrowse link 19 45,349,837 45,370,647 RGD:2290271
positive regulation of reciprocal meiotic recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PRDM7 PR/SET domain 7 JBrowse link 16 90,056,566 90,077,339 RGD:2290271
G PRDM9 PR/SET domain 9 JBrowse link 5 23,507,155 23,528,093 RGD:2290271
G UBE2B ubiquitin conjugating enzyme E2 B JBrowse link 5 134,371,569 134,392,108 RGD:2290271
positive regulation of strand invasion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G WRN WRN RecQ like helicase JBrowse link 8 31,033,749 31,176,138 RGD:2290271
regulation of double-strand break repair via homologous recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CHEK1 checkpoint kinase 1 JBrowse link 11 125,624,910 125,676,256 RGD:2290271
G FIGN fidgetin, microtubule severing factor JBrowse link 2 163,602,611 163,736,155 RGD:2290271
G FIGNL1 fidgetin like 1 JBrowse link 7 50,437,320 50,450,406 RGD:2290271
G FIGNL2 fidgetin like 2 JBrowse link 12 51,817,892 51,848,753 RGD:2290271
G KDM1A lysine demethylase 1A JBrowse link 1 23,019,443 23,083,691 RGD:2290271
G PPP4C protein phosphatase 4 catalytic subunit JBrowse link 16 30,075,994 30,085,377 RGD:2290271
G PPP4R2 protein phosphatase 4 regulatory subunit 2 JBrowse link 3 72,996,743 73,069,201 RGD:2290271
G RAD51 RAD51 recombinase JBrowse link 15 40,694,774 40,732,340 RGD:2290271
G RAD51AP1 RAD51 associated protein 1 JBrowse link 12 4,538,890 4,560,047 RGD:2290271
G RPA2 replication protein A2 JBrowse link 1 27,891,524 27,914,797 RGD:2290271
G RTEL1 regulator of telomere elongation helicase 1 JBrowse link 20 63,657,810 63,696,253 RGD:2290271
G RTEL1-TNFRSF6B RTEL1-TNFRSF6B readthrough (NMD candidate) JBrowse link 20 63,657,810 63,698,698 RGD:2290271
G SETD2 SET domain containing 2, histone lysine methyltransferase JBrowse link 3 47,016,408 47,164,113 RGD:2290271
G SIRT6 sirtuin 6 JBrowse link 19 4,174,109 4,182,563 RGD:2290271
G SPIDR scaffold protein involved in DNA repair JBrowse link 8 47,260,878 47,736,306 RGD:2290271
G TERF2IP TERF2 interacting protein JBrowse link 16 75,647,737 75,657,442 RGD:2290271
G TEX15 testis expressed 15, meiosis and synapsis associated JBrowse link 8 30,831,544 30,913,008 RGD:2290271
G USP51 ubiquitin specific peptidase 51 JBrowse link X 55,484,524 55,489,875 RGD:2290271
G ZNF365 zinc finger protein 365 JBrowse link 10 62,374,157 62,672,011 RGD:2290271
regulation of isotype switching term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G APLF aprataxin and PNKP like factor JBrowse link 2 68,467,585 68,580,162 RGD:2290271
G IL10 interleukin 10 JBrowse link 1 206,767,602 206,772,494 RGD:2290271
G IL4 interleukin 4 JBrowse link 5 132,673,986 132,682,678 RGD:2290271
G SUPT6H SPT6 homolog, histone chaperone and transcription elongation factor JBrowse link 17 28,662,183 28,702,679 RGD:2290271
regulation of isotype switching to IgG isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G FOXP3 forkhead box P3 JBrowse link X 49,250,436 49,264,932 RGD:2290271
G IL27RA interleukin 27 receptor subunit alpha JBrowse link 19 14,031,762 14,053,218 RGD:2290271
G NDFIP1 Nedd4 family interacting protein 1 JBrowse link 5 142,108,779 142,154,440 RGD:2290271
regulation of mitotic recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ERCC2 ERCC excision repair 2, TFIIH core complex helicase subunit JBrowse link 19 45,349,837 45,370,647 RGD:2290271
G MRE11 MRE11 homolog, double strand break repair nuclease JBrowse link 11 94,415,570 94,512,701 RGD:2290271
G RAD50 RAD50 double strand break repair protein JBrowse link 5 132,556,977 132,646,349 RGD:2290271

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18019
    metabolic process 11614
      regulation of metabolic process 6880
        regulation of macromolecule metabolic process 6319
          regulation of DNA metabolic process 368
            regulation of DNA recombination 108
              negative regulation of DNA recombination + 45
              positive regulation of DNA recombination + 44
              regulation of DNA recombination at centromere + 0
              regulation of DNA recombination at telomere + 2
              regulation of double-strand break repair via homologous recombination + 48
              regulation of isotype switching + 37
              regulation of mitotic recombination + 6
              regulation of reciprocal meiotic recombination + 3
              regulation of single-strand break repair via homologous recombination + 0
              regulation of strand invasion + 1
              regulation of transposition, DNA-mediated + 0
Path 2
Term Annotations click to browse term
  biological_process 18019
    metabolic process 11614
      cellular metabolic process 10895
        cellular aromatic compound metabolic process 6020
          nucleobase-containing compound metabolic process 5796
            nucleic acid metabolic process 5262
              DNA metabolic process 969
                regulation of DNA metabolic process 368
                  regulation of DNA recombination 108
                    negative regulation of DNA recombination + 45
                    positive regulation of DNA recombination + 44
                    regulation of DNA recombination at centromere + 0
                    regulation of DNA recombination at telomere + 2
                    regulation of double-strand break repair via homologous recombination + 48
                    regulation of isotype switching + 37
                    regulation of mitotic recombination + 6
                    regulation of reciprocal meiotic recombination + 3
                    regulation of single-strand break repair via homologous recombination + 0
                    regulation of strand invasion + 1
                    regulation of transposition, DNA-mediated + 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.