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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of DNA recombination
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Accession:GO:0000018 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of DNA recombination, a DNA metabolic process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents.


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regulation of DNA recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Smarcad1 SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 JBrowse link 6 65,042,591 65,116,061 RGD:2290270
G Thoc1 THO complex 1 JBrowse link 18 9,958,180 9,995,484 RGD:2290270
negative regulation of DNA recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Blm Bloom syndrome, RecQ like helicase JBrowse link 7 80,454,993 80,535,148 RGD:2290270
G H1f0 H1.0 linker histone JBrowse link 15 79,028,212 79,030,504 RGD:2290270
G H1f1 H1.1 linker histone, cluster member JBrowse link 13 23,763,668 23,764,412 RGD:2290270
G H1f10 H1.10 linker histone JBrowse link 6 87,980,421 87,981,482 RGD:2290270
G H1f2 H1.2 linker histone, cluster member JBrowse link 13 23,738,807 23,739,531 RGD:2290270
G H1f3 H1.3 linker histone, cluster member JBrowse link 13 23,555,032 23,555,807 RGD:2290270
G H1f4 H1.4 linker histone, cluster member JBrowse link 13 23,621,777 23,622,558 RGD:2290270
G H1f5 H1.5 linker histone, cluster member JBrowse link 13 21,779,832 21,780,625 RGD:2290270
G H1f6 H1.6 linker histone, cluster member JBrowse link 13 23,695,811 23,696,545 RGD:2290270
G H1f7 H1.7 linker histone JBrowse link 15 98,255,982 98,257,307 RGD:2290270
G H1f8 H1.8 linker histone JBrowse link 6 115,944,931 115,950,242 RGD:2290270
G Hils1 histone H1-like protein in spermatids 1 JBrowse link 11 94,967,593 94,968,456 RGD:2290270
G Lig3 ligase III, DNA, ATP-dependent JBrowse link 11 82,781,109 82,804,274 RGD:2290270
G Msh2 mutS homolog 2 JBrowse link 17 87,672,532 87,723,713 RGD:2290270
G Msh3 mutS homolog 3 JBrowse link 13 92,211,878 92,355,004 RGD:2290270
G Msh6 mutS homolog 6 JBrowse link 17 87,975,050 87,990,892 RGD:2290270
G Rad18 RAD18 E3 ubiquitin protein ligase JBrowse link 6 112,619,851 112,696,691 RGD:2290270
G Rtel1 regulator of telomere elongation helicase 1 JBrowse link 2 181,319,711 181,356,616 RGD:2290270
G Zranb3 zinc finger, RAN-binding domain containing 3 JBrowse link 1 127,954,179 128,103,053 RGD:2290270
negative regulation of DNA recombination at telomere term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pot1b protection of telomeres 1B JBrowse link 17 55,651,190 55,712,647 RGD:2290270
G Terf2ip telomeric repeat binding factor 2, interacting protein JBrowse link 8 112,011,359 112,020,528 RGD:2290270
negative regulation of double-strand break repair via homologous recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cgas cyclic GMP-AMP synthase JBrowse link 9 78,430,518 78,443,237 RGD:2290270
G Fancb Fanconi anemia, complementation group B JBrowse link X 164,980,480 164,997,272 RGD:2290270
G Fbh1 F-box DNA helicase 1 JBrowse link 2 11,742,573 11,777,585 RGD:2290270
G Helb helicase (DNA) B JBrowse link 10 120,083,608 120,113,010 RGD:2290270
G Klhl15 kelch-like 15 JBrowse link X 94,232,278 94,277,724 RGD:2290270
G Mad2l2 MAD2 mitotic arrest deficient-like 2 JBrowse link 4 148,130,158 148,145,704 RGD:2290270
G Parpbp PARP1 binding protein JBrowse link 10 88,091,398 88,146,969 RGD:2290270
G Polq polymerase (DNA directed), theta JBrowse link 16 37,011,741 37,095,419 RGD:2290270
G Radx RPA1 related single stranded DNA binding protein, X-linked JBrowse link X 139,480,367 139,554,584 RGD:2290270
G Recql5 RecQ protein-like 5 JBrowse link 11 115,892,595 115,933,514 RGD:2290270
G Rif1 replication timing regulatory factor 1 JBrowse link 2 52,072,815 52,126,769 RGD:2290270
G Rmi2 RecQ mediated genome instability 2 JBrowse link 16 10,835,059 10,843,235 RGD:2290270
G Shld1 shieldin complex subunit 1 JBrowse link 2 132,686,931 132,751,055 RGD:2290270
G Shld2 shieldin complex subunit 2 JBrowse link 14 34,236,948 34,310,651 RGD:2290270
G Smchd1 SMC hinge domain containing 1 JBrowse link 17 71,344,489 71,475,366 RGD:2290270
G Trp53bp1 transformation related protein 53 binding protein 1 JBrowse link 2 121,194,835 121,296,354 RGD:2290270
G Ubqln4 ubiquilin 4 JBrowse link 3 88,553,677 88,569,725 RGD:2290270
negative regulation of isotype switching term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Parp3 poly (ADP-ribose) polymerase family, member 3 JBrowse link 9 106,470,322 106,476,949 RGD:2290270
negative regulation of isotype switching to IgA isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Thoc1 THO complex 1 JBrowse link 18 9,958,180 9,995,484 RGD:2290270
negative regulation of isotype switching to IgE isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bcl6 B cell leukemia/lymphoma 6 JBrowse link 16 23,965,050 23,988,866 RGD:2290270
G Foxp3 forkhead box P3 JBrowse link X 7,579,676 7,595,243 RGD:2290270
G Ndfip1 Nedd4 family interacting protein 1 JBrowse link 18 38,418,907 38,465,197 RGD:2290270
negative regulation of mitotic recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ankle1 ankyrin repeat and LEM domain containing 1 JBrowse link 8 71,405,986 71,410,728 RGD:2290270
G Blm Bloom syndrome, RecQ like helicase JBrowse link 7 80,454,993 80,535,148 RGD:2290270
G Mlh1 mutL homolog 1 JBrowse link 9 111,228,228 111,271,786 RGD:2290270
G Zscan4c zinc finger and SCAN domain containing 4C JBrowse link 7 11,005,745 11,010,547 RGD:2290270
negative regulation of telomere maintenance via recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Terf2 telomeric repeat binding factor 2 JBrowse link 8 107,069,400 107,096,548 RGD:2290270
positive regulation of double-strand break repair via homologous recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Actr2 ARP2 actin-related protein 2 JBrowse link 11 20,062,304 20,112,951 RGD:2290270
G Arid2 AT rich interactive domain 2 (ARID, RFX-like) JBrowse link 15 96,287,522 96,405,463 RGD:2290270
G Blm Bloom syndrome, RecQ like helicase JBrowse link 7 80,454,993 80,535,148 RGD:2290270
G Ercc6 excision repair cross-complementing rodent repair deficiency, complementation group 6 JBrowse link 14 32,513,291 32,580,990 RGD:2290270
G Fancb Fanconi anemia, complementation group B JBrowse link X 164,980,480 164,997,272 RGD:2290270
G Mms19 MMS19 cytosolic iron-sulfur assembly component JBrowse link 19 41,943,707 41,981,207 RGD:2290270
G Mrnip MRN complex interacting protein JBrowse link 11 50,174,851 50,200,116 RGD:2290270
G Parp1 poly (ADP-ribose) polymerase family, member 1 JBrowse link 1 180,568,891 180,600,999 RGD:2290270
G Timeless timeless circadian clock 1 JBrowse link 10 128,232,063 128,252,941 RGD:2290270
G Was Wiskott-Aldrich syndrome JBrowse link X 8,081,466 8,090,491 RGD:2290270
G Wrap53 WD repeat containing, antisense to Trp53 JBrowse link 11 69,561,754 69,580,250 RGD:2290270
positive regulation of interleukin-4-dependent isotype switching to IgE isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Tnfsf4 tumor necrosis factor (ligand) superfamily, member 4 JBrowse link 1 161,395,438 161,418,206 RGD:2290270
positive regulation of isotype switching term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Exosc3 exosome component 3 JBrowse link 4 45,316,613 45,320,616 RGD:2290270
G Exosc6 exosome component 6 JBrowse link 8 111,056,339 111,057,664 RGD:2290270
G Hmces 5-hydroxymethylcytosine (hmC) binding, ES cell specific JBrowse link 6 87,913,907 87,936,619 RGD:2290270
G Kmt5b lysine methyltransferase 5B JBrowse link 19 3,767,362 3,818,303 RGD:2290270
G Kmt5c lysine methyltransferase 5C JBrowse link 7 4,740,092 4,747,514 RGD:2290270
G Mad2l2 MAD2 mitotic arrest deficient-like 2 JBrowse link 4 148,130,158 148,145,704 RGD:2290270
G Paxip1 PAX interacting (with transcription-activation domain) protein 1 JBrowse link 5 27,740,080 27,791,672 RGD:2290270
G Rif1 replication timing regulatory factor 1 JBrowse link 2 52,072,815 52,126,769 RGD:2290270
G Shld1 shieldin complex subunit 1 JBrowse link 2 132,686,931 132,751,055 RGD:2290270
G Shld2 shieldin complex subunit 2 JBrowse link 14 34,236,948 34,310,651 RGD:2290270
G Tfrc transferrin receptor JBrowse link 16 32,608,896 32,632,794 RGD:2290270
G Trp53bp1 transformation related protein 53 binding protein 1 JBrowse link 2 121,194,835 121,296,354 RGD:2290270
positive regulation of isotype switching to IgA isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mlh1 mutL homolog 1 JBrowse link 9 111,228,228 111,271,786 RGD:2290270
G Msh2 mutS homolog 2 JBrowse link 17 87,672,532 87,723,713 RGD:2290270
G Nsd2 nuclear receptor binding SET domain protein 2 JBrowse link 5 33,820,676 33,897,966 RGD:2290270
G Pms2 PMS1 homolog2, mismatch repair system component JBrowse link 5 143,909,901 143,972,745 RGD:2290270
G Tgfb1 transforming growth factor, beta 1 JBrowse link 7 25,687,002 25,705,077 RGD:2290270
G Tnfsf13 tumor necrosis factor (ligand) superfamily, member 13 JBrowse link 11 69,682,577 69,685,554 RGD:2290270
positive regulation of isotype switching to IgE isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Clcf1 cardiotrophin-like cytokine factor 1 JBrowse link 19 4,214,238 4,223,505 RGD:2290270
G Il4 interleukin 4 JBrowse link 11 53,612,460 53,618,665 RGD:2290270
G Stat6 signal transducer and activator of transcription 6 JBrowse link 10 127,642,955 127,660,987 RGD:2290270
positive regulation of isotype switching to IgG isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atad5 ATPase family, AAA domain containing 5 JBrowse link 11 80,089,379 80,135,797 RGD:2290270
G Cd28 CD28 antigen JBrowse link 1 60,746,388 60,773,359 RGD:2290270
G Cd40 CD40 antigen JBrowse link 2 165,055,614 165,071,654 RGD:2290270
G Ifng interferon gamma JBrowse link 10 118,441,046 118,445,894 RGD:2290270
G Il2 interleukin 2 JBrowse link 3 37,120,713 37,125,954 RGD:2290270
G Il4 interleukin 4 JBrowse link 11 53,612,460 53,618,665 RGD:2290270
G Mlh1 mutL homolog 1 JBrowse link 9 111,228,228 111,271,786 RGD:2290270
G Msh2 mutS homolog 2 JBrowse link 17 87,672,532 87,723,713 RGD:2290270
G Pagr1a PAXIP1 associated glutamate rich protein 1A JBrowse link 7 127,015,051 127,017,352 RGD:2290270
G Paxip1 PAX interacting (with transcription-activation domain) protein 1 JBrowse link 5 27,740,080 27,791,672 RGD:2290270
G Pms2 PMS1 homolog2, mismatch repair system component JBrowse link 5 143,909,901 143,972,745 RGD:2290270
G Ptprc protein tyrosine phosphatase, receptor type, C JBrowse link 1 138,062,859 138,175,756 RGD:2290270
G Tbx21 T-box 21 JBrowse link 11 97,098,007 97,115,331 RGD:2290270
positive regulation of mitotic recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ercc2 excision repair cross-complementing rodent repair deficiency, complementation group 2 JBrowse link 7 19,382,017 19,395,694 RGD:2290270
positive regulation of reciprocal meiotic recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Prdm9 PR domain containing 9 JBrowse link 17 15,543,072 15,564,374 RGD:2290270
G Ube2b ubiquitin-conjugating enzyme E2B JBrowse link 11 51,985,138 52,004,145 RGD:2290270
positive regulation of strand invasion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Wrn Werner syndrome RecQ like helicase JBrowse link 8 33,234,372 33,385,543 RGD:2290270
regulation of double-strand break repair via homologous recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Chek1 checkpoint kinase 1 JBrowse link 9 36,708,482 36,726,658 RGD:2290270
G Fign fidgetin JBrowse link 2 63,971,508 64,098,038 RGD:2290270
G Fignl1 fidgetin-like 1 JBrowse link 11 11,800,288 11,808,995 RGD:2290270
G Fignl2 fidgetin-like 2 JBrowse link 15 101,050,192 101,078,584 RGD:2290270
G Kdm1a lysine (K)-specific demethylase 1A JBrowse link 4 136,550,533 136,602,787 RGD:2290270
G Ppp4c protein phosphatase 4, catalytic subunit JBrowse link 7 126,785,866 126,792,557 RGD:2290270
G Ppp4r2 protein phosphatase 4, regulatory subunit 2 JBrowse link 6 100,833,620 100,869,934 RGD:2290270
G Rad51 RAD51 recombinase JBrowse link 2 119,112,814 119,136,073 RGD:2290270
G Rad51ap1 RAD51 associated protein 1 JBrowse link 6 126,923,415 126,939,621 RGD:2290270
G Rpa2 replication protein A2 JBrowse link 4 132,768,360 132,778,746 RGD:2290270
G Rtel1 regulator of telomere elongation helicase 1 JBrowse link 2 181,319,711 181,356,616 RGD:2290270
G Setd2 SET domain containing 2 JBrowse link 9 110,532,500 110,618,633 RGD:2290270
G Shld3 shieldin complex subunit 3 JBrowse link 13 104,173,721 104,178,459 RGD:2290270
G Sirt6 sirtuin 6 JBrowse link 10 81,621,786 81,627,792 RGD:2290270
G Spidr scaffolding protein involved in DNA repair JBrowse link 16 15,889,224 16,146,851 RGD:2290270
G Terf2ip telomeric repeat binding factor 2, interacting protein JBrowse link 8 112,011,359 112,020,528 RGD:2290270
G Tex15 testis expressed gene 15 JBrowse link 8 33,516,689 33,592,503 RGD:2290270
G Usp51 ubiquitin specific protease 51 JBrowse link X 153,006,469 153,011,364 RGD:2290270
G Zfp365 zinc finger protein 365 JBrowse link 10 67,886,105 67,912,662 RGD:2290270
regulation of isotype switching term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aplf aprataxin and PNKP like factor JBrowse link 6 87,628,425 87,672,237 RGD:2290270
G Mir181b-1 microRNA 181b-1 JBrowse link 1 137,966,639 137,966,718 RGD:2290270
G Mir181b-2 microRNA 181b-2 JBrowse link 2 38,853,830 38,853,918 RGD:2290270
G Supt6 SPT6, histone chaperone and transcription elongation factor JBrowse link 11 78,206,749 78,245,972 RGD:2290270
regulation of isotype switching to IgG isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Foxp3 forkhead box P3 JBrowse link X 7,579,676 7,595,243 RGD:2290270
G Il27ra interleukin 27 receptor, alpha JBrowse link 8 84,030,286 84,042,600 RGD:2290270
G Ndfip1 Nedd4 family interacting protein 1 JBrowse link 18 38,418,907 38,465,197 RGD:2290270
regulation of mitotic recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ercc2 excision repair cross-complementing rodent repair deficiency, complementation group 2 JBrowse link 7 19,382,017 19,395,694 RGD:2290270
G Rad50 RAD50 double strand break repair protein JBrowse link 11 53,649,519 53,707,319 RGD:2290270

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 23110
    metabolic process 10615
      regulation of metabolic process 6244
        regulation of macromolecule metabolic process 5742
          regulation of DNA metabolic process 376
            regulation of DNA recombination 107
              negative regulation of DNA recombination + 47
              positive regulation of DNA recombination + 45
              regulation of DNA recombination at centromere + 0
              regulation of DNA recombination at telomere + 3
              regulation of double-strand break repair via homologous recombination + 46
              regulation of isotype switching + 40
              regulation of mitotic recombination + 7
              regulation of reciprocal meiotic recombination + 2
              regulation of single-strand break repair via homologous recombination + 0
              regulation of strand invasion + 1
              regulation of transposition, DNA-mediated + 0
Path 2
Term Annotations click to browse term
  biological_process 23110
    metabolic process 10615
      cellular metabolic process 9574
        cellular aromatic compound metabolic process 5075
          nucleobase-containing compound metabolic process 4857
            nucleic acid metabolic process 4426
              DNA metabolic process 842
                regulation of DNA metabolic process 376
                  regulation of DNA recombination 107
                    negative regulation of DNA recombination + 47
                    positive regulation of DNA recombination + 45
                    regulation of DNA recombination at centromere + 0
                    regulation of DNA recombination at telomere + 3
                    regulation of double-strand break repair via homologous recombination + 46
                    regulation of isotype switching + 40
                    regulation of mitotic recombination + 7
                    regulation of reciprocal meiotic recombination + 2
                    regulation of single-strand break repair via homologous recombination + 0
                    regulation of strand invasion + 1
                    regulation of transposition, DNA-mediated + 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.