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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of DNA recombination
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Accession:GO:0000018 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of DNA recombination, a DNA metabolic process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents.


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regulation of DNA recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G SMARCAD1 SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 JBrowse link 8 125,410,221 125,488,471 RGD:14298760
negative regulation of DNA recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BLM BLM RecQ like helicase JBrowse link 7 53,317,515 53,412,649 RGD:14298760
G H1-3 H1.3 linker histone, cluster member RGD:14298760
G H1-4 H1.4 linker histone, cluster member RGD:14298760
G H1FOO oocyte-specific H1 histone JBrowse link 13 68,921,491 68,943,061 RGD:14298760
G LOC100510904 histone H1.0 JBrowse link 5 10,038,944 10,041,242 RGD:14298760
G LOC100516553 testis-specific H1 histone JBrowse link 5 78,699,291 78,700,227 RGD:14298760
G MSH2 mutS homolog 2 JBrowse link 3 93,082,958 93,163,556 RGD:14298760
G MSH3 mutS homolog 3 JBrowse link 2 89,255,647 89,456,102 RGD:14298760
G MSH6 mutS homolog 6 JBrowse link 3 92,792,590 92,814,154 RGD:14298760
G RTEL1 regulator of telomere elongation helicase 1 JBrowse link 17 62,611,844 62,636,628 RGD:14298760
G ZRANB3 zinc finger RANBP2-type containing 3 JBrowse link 15 16,414,291 16,727,659 RGD:14298760
negative regulation of DNA recombination at telomere term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G TERF2IP TERF2 interacting protein JBrowse link 6 12,047,409 12,057,451 RGD:14298760
negative regulation of double-strand break repair via homologous recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CGAS cyclic GMP-AMP synthase JBrowse link 1 92,483,253 92,500,376 RGD:14298760
G FANCB FA complementation group B JBrowse link X 11,386,360 11,408,958 RGD:14298760
G FBH1 F-box DNA helicase 1 JBrowse link 10 65,060,714 65,108,975 RGD:14298760
G HELB DNA helicase B JBrowse link 5 30,645,378 30,696,488 RGD:14298760
G KLHL15 kelch like family member 15 JBrowse link X 20,088,208 20,130,452 RGD:14298760
G MAD2L2 mitotic arrest deficient 2 like 2 JBrowse link 6 71,773,680 71,779,192 RGD:14298760
G MAGEF1 MAGE family member F1 JBrowse link 13 122,600,984 122,602,700 RGD:14298760
G PARPBP PARP1 binding protein JBrowse link 5 82,018,857 82,091,946 RGD:14298760
G POLQ DNA polymerase theta JBrowse link 13 138,962,634 139,108,499 RGD:14298760
G RADX RPA1 related single stranded DNA binding protein, X-linked JBrowse link X 87,025,603 87,103,503 RGD:14298760
G RECQL5 RecQ like helicase 5 JBrowse link 12 5,732,336 5,770,136 RGD:14298760
G RIF1 replication timing regulatory factor 1 JBrowse link 15 769,518 832,036 RGD:14298760
G RMI2 RecQ mediated genome instability 2 JBrowse link 3 31,807,717 31,814,869 RGD:14298760
G SHLD1 shieldin complex subunit 1 JBrowse link 17 14,610,723 14,706,082 RGD:14298760
G SHLD2 shieldin complex subunit 2 JBrowse link 14 88,005,599 88,121,155 RGD:14298760
G SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1 JBrowse link 6 103,809,732 103,986,057 RGD:14298760
G TP53BP1 tumor protein p53 binding protein 1 JBrowse link 1 127,958,500 128,032,370 RGD:14298760
G UBQLN4 ubiquilin 4 JBrowse link 4 93,976,386 93,994,830 RGD:14298760
negative regulation of isotype switching term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PARP3 poly(ADP-ribose) polymerase family member 3 JBrowse link 13 34,075,807 34,084,384 RGD:14298760
negative regulation of isotype switching to IgE isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BCL6 BCL6 transcription repressor JBrowse link 13 125,377,247 125,401,328 RGD:14298760
G FOXP3 forkhead box P3 JBrowse link X 43,303,777 43,328,164 RGD:14298760
G NDFIP1 Nedd4 family interacting protein 1 JBrowse link 2 143,688,946 143,734,523 RGD:14298760
negative regulation of mitotic recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ANKLE1 ankyrin repeat and LEM domain containing 1 JBrowse link 2 60,391,110 60,397,559 RGD:14298760
G MLH1 mutL homolog 1 JBrowse link 13 21,791,276 21,877,789 RGD:14298760
negative regulation of telomere maintenance via recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G TERF2 telomeric repeat binding factor 2 JBrowse link 6 17,605,748 17,631,795 RGD:14298760
positive regulation of double-strand break repair via homologous recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ACTR2 actin related protein 2 JBrowse link 3 76,691,275 76,729,269 RGD:14298760
G ARID2 AT-rich interaction domain 2 JBrowse link 5 76,637,385 76,800,155 RGD:14298760
G ERCC6 ERCC excision repair 6, chromatin remodeling factor JBrowse link 14 89,998,125 90,075,911 RGD:14298760
G FANCB FA complementation group B JBrowse link X 11,386,360 11,408,958 RGD:14298760
G FUS FUS RNA binding protein JBrowse link 3 17,314,936 17,326,663 RGD:14298760
G MMS19 MMS19 homolog, cytosolic iron-sulfur assembly component JBrowse link 14 108,853,038 108,886,587 RGD:14298760
G PARP1 poly(ADP-ribose) polymerase 1 JBrowse link 10 14,203,157 14,241,164 RGD:14298760
G TIMELESS timeless circadian regulator RGD:14298760
G WAS WASP actin nucleation promoting factor JBrowse link X 42,774,597 42,793,055 RGD:14298760
G WRAP53 WD repeat containing antisense to TP53 JBrowse link 12 52,954,674 52,968,371 RGD:14298760
positive regulation of isotype switching term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G EXOSC3 exosome component 3 JBrowse link 1 238,536,341 238,541,756 RGD:14298760
G EXOSC6 exosome component 6 JBrowse link 6 13,295,591 13,296,942 RGD:14298760
G HMCES 5-hydroxymethylcytosine binding, ES cell specific JBrowse link 13 71,732,311 71,752,296 RGD:14298760
G KMT5B lysine methyltransferase 5B JBrowse link 2 4,710,510 4,768,237 RGD:14298760
G KMT5C lysine methyltransferase 5C JBrowse link 6 59,517,058 59,524,551 RGD:14298760
G MAD2L2 mitotic arrest deficient 2 like 2 JBrowse link 6 71,773,680 71,779,192 RGD:14298760
G RIF1 replication timing regulatory factor 1 JBrowse link 15 769,518 832,036 RGD:14298760
G SHLD1 shieldin complex subunit 1 JBrowse link 17 14,610,723 14,706,082 RGD:14298760
G SHLD2 shieldin complex subunit 2 JBrowse link 14 88,005,599 88,121,155 RGD:14298760
G TFRC transferrin receptor JBrowse link 13 133,976,765 133,997,554 RGD:14298760
G TP53BP1 tumor protein p53 binding protein 1 JBrowse link 1 127,958,500 128,032,370 RGD:14298760
positive regulation of isotype switching to IgA isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G MLH1 mutL homolog 1 JBrowse link 13 21,791,276 21,877,789 RGD:14298760
G MSH2 mutS homolog 2 JBrowse link 3 93,082,958 93,163,556 RGD:14298760
G NSD2 nuclear receptor binding SET domain protein 2 JBrowse link 8 938,832 1,018,032 RGD:14298760
G TGFB1 transforming growth factor beta 1 JBrowse link 6 49,332,169 49,348,642 RGD:14298760
G TNFSF13 TNF superfamily member 13 JBrowse link 12 52,853,646 52,857,033 RGD:14298760
positive regulation of isotype switching to IgE isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G STAT6 signal transducer and activator of transcription 6 JBrowse link 5 22,406,356 22,422,412 RGD:14298760
positive regulation of isotype switching to IgG isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ATAD5 ATPase family AAA domain containing 5 JBrowse link 12 42,874,705 42,920,438 RGD:14298760
G CD28 CD28 molecule JBrowse link 15 107,128,103 107,155,431 RGD:14298760
G CD40 CD40 molecule JBrowse link 17 48,286,116 48,298,188 RGD:14298760
G IL2 interleukin 2 JBrowse link 8 101,640,938 101,645,683 RGD:14298760
G MLH1 mutL homolog 1 JBrowse link 13 21,791,276 21,877,789 RGD:14298760
G MSH2 mutS homolog 2 JBrowse link 3 93,082,958 93,163,556 RGD:14298760
G PAXIP1 PAX interacting protein 1 JBrowse link 18 3,066,853 3,111,239 RGD:14298760
G PTPRC protein tyrosine phosphatase receptor type C JBrowse link 10 21,482,984 21,601,627 RGD:14298760
G TBX21 T-box transcription factor 21 JBrowse link 12 23,996,415 24,009,353 RGD:14298760
positive regulation of mitotic recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ERCC2 ERCC excision repair 2, TFIIH core complex helicase subunit JBrowse link 6 51,734,318 51,757,508 RGD:14298760
positive regulation of reciprocal meiotic recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G UBE2B ubiquitin conjugating enzyme E2 B JBrowse link 2 136,652,764 136,667,213 RGD:14298760
positive regulation of strand invasion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G WRN WRN RecQ like helicase JBrowse link 15 53,966,968 54,094,855 RGD:14298760
regulation of double-strand break repair via homologous recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G FIGN fidgetin, microtubule severing factor JBrowse link 15 70,255,270 70,394,095 RGD:14298760
G FIGNL1 fidgetin like 1 JBrowse link 9 136,484,217 136,488,262 RGD:14298760
G KDM1A lysine demethylase 1A JBrowse link 6 80,903,407 80,971,875 RGD:14298760
G PPP4C protein phosphatase 4 catalytic subunit JBrowse link 3 18,262,817 18,271,588 RGD:14298760
G PPP4R2 protein phosphatase 4 regulatory subunit 2 JBrowse link 13 54,324,978 54,378,277 RGD:14298760
G RAD51 RAD51 recombinase JBrowse link 1 130,592,414 130,640,326 RGD:14298760
G RAD51AP1 RAD51 associated protein 1 JBrowse link 5 65,872,277 65,897,210 RGD:14298760
G RPA2 replication protein A2 JBrowse link 6 85,032,604 85,045,899 RGD:14298760
G RTEL1 regulator of telomere elongation helicase 1 JBrowse link 17 62,611,844 62,636,628 RGD:14298760
G SIRT6 sirtuin 6 JBrowse link 2 74,568,539 74,577,774 RGD:14298760
G SPIDR scaffold protein involved in DNA repair JBrowse link 4 79,874,937 80,190,744 RGD:14298760
G TERF2IP TERF2 interacting protein JBrowse link 6 12,047,409 12,057,451 RGD:14298760
G TRAPPC13 trafficking protein particle complex 13 JBrowse link 16 44,146,574 44,186,346 RGD:14298760
G USP51 ubiquitin specific peptidase 51 JBrowse link X 48,047,658 48,051,941 RGD:14298760
G ZNF365 zinc finger protein 365 JBrowse link 14 65,861,398 65,888,341 RGD:14298760
regulation of isotype switching term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G APLF aprataxin and PNKP like factor JBrowse link 3 73,752,115 73,831,158 RGD:14298760
G SUPT6H SPT6 homolog, histone chaperone and transcription elongation factor JBrowse link 12 44,916,716 44,940,732 RGD:14298760
regulation of isotype switching to IgG isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G FOXP3 forkhead box P3 JBrowse link X 43,303,777 43,328,164 RGD:14298760
G IL27RA interleukin 27 receptor subunit alpha JBrowse link 2 65,127,278 65,149,665 RGD:14298760
G NDFIP1 Nedd4 family interacting protein 1 JBrowse link 2 143,688,946 143,734,523 RGD:14298760
regulation of mitotic recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ERCC2 ERCC excision repair 2, TFIIH core complex helicase subunit JBrowse link 6 51,734,318 51,757,508 RGD:14298760

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 14973
    metabolic process 9067
      regulation of metabolic process 4916
        regulation of macromolecule metabolic process 4567
          regulation of DNA metabolic process 253
            regulation of DNA recombination 83
              negative regulation of DNA recombination + 37
              positive regulation of DNA recombination + 37
              regulation of DNA recombination at centromere + 0
              regulation of DNA recombination at telomere + 2
              regulation of double-strand break repair via homologous recombination + 42
              regulation of isotype switching + 31
              regulation of mitotic recombination + 4
              regulation of reciprocal meiotic recombination + 1
              regulation of single-strand break repair via homologous recombination + 0
              regulation of strand invasion + 1
              regulation of transposition, DNA-mediated + 0
Path 2
Term Annotations click to browse term
  biological_process 14973
    metabolic process 9067
      cellular metabolic process 8274
        cellular aromatic compound metabolic process 4332
          nucleobase-containing compound metabolic process 4190
            nucleic acid metabolic process 3842
              DNA metabolic process 657
                regulation of DNA metabolic process 253
                  regulation of DNA recombination 83
                    negative regulation of DNA recombination + 37
                    positive regulation of DNA recombination + 37
                    regulation of DNA recombination at centromere + 0
                    regulation of DNA recombination at telomere + 2
                    regulation of double-strand break repair via homologous recombination + 42
                    regulation of isotype switching + 31
                    regulation of mitotic recombination + 4
                    regulation of reciprocal meiotic recombination + 1
                    regulation of single-strand break repair via homologous recombination + 0
                    regulation of strand invasion + 1
                    regulation of transposition, DNA-mediated + 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.