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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of DNA recombination
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Accession:GO:0000018 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of DNA recombination, a DNA metabolic process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents.


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regulation of DNA recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Alyref Aly/REF export factor JBrowse link 10 109,768,593 109,774,639 RGD:1624291
G Da2-19 uncharacterized LOC302729 JBrowse link X 48,196,789 48,213,506 RGD:1600115
G Smarcad1 SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1` JBrowse link 4 95,884,020 95,945,248 RGD:1624291
G Thoc1 THO complex 1 JBrowse link 18 1,142,540 1,177,084 RGD:1624291
negative regulation of DNA recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Blm BLM RecQ like helicase JBrowse link 1 142,246,773 142,332,616 RGD:1624291
G H1f0 H1 histone family, member 0 JBrowse link 7 120,260,776 120,262,636 RGD:13792537
G H1f1 H1.1 linker histone, cluster member JBrowse link 17 43,614,101 43,614,844 RGD:13792537
G H1f10 H1.10 linker histone JBrowse link 4 119,889,016 119,892,661 RGD:13792537
G H1f2 H1.2 linker histone, cluster member JBrowse link 17 43,638,938 43,640,445 RGD:13792537
G H1f4 H1.4 linker histone, cluster member JBrowse link 17 43,734,461 43,735,120 RGD:13792537
G H1f5 H1.5 linker histone, cluster member JBrowse link 17 44,766,313 44,766,981 RGD:13792537
G H1f6 H1.6 linker histone, cluster member JBrowse link 17 43,675,190 43,675,934 RGD:13792537
G H1f7 H1.7 linker histone JBrowse link 7 139,871,491 139,872,858 RGD:13792537
G H1f8 H1.8 linker histone JBrowse link 4 147,844,658 147,849,779 RGD:13792537
G H4f3 H1.3 linker histone, cluster member JBrowse link 17 43,797,711 43,798,450 RGD:13792537
G Hils1 histone linker H1 domain, spermatid-specific 1 JBrowse link 10 82,775,691 82,776,487 RGD:13792537
G Lig3 DNA ligase 3 JBrowse link 10 70,134,734 70,158,051 RGD:1624291
G Msh2 mutS homolog 2 JBrowse link 6 11,215,951 11,274,916 RGD:1624291
RGD:13792537
RGD:1600115
G Msh3 mutS homolog 3 JBrowse link 2 21,790,048 21,931,791 RGD:1624291
G Msh6 mutS homolog 6 JBrowse link 6 11,644,565 11,662,389 RGD:1624291
RGD:13792537
G Rad18 RAD18 E3 ubiquitin protein ligase JBrowse link 4 144,537,329 144,620,606 RGD:1624291
G Rtel1 regulator of telomere elongation helicase 1 JBrowse link 3 176,818,012 176,856,531 RGD:1624291
RGD:13792537
G Zranb3 zinc finger RANBP2-type containing 3 JBrowse link 13 44,661,375 44,812,430 RGD:1624291
negative regulation of DNA recombination at telomere term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pot1b protection of telomeres 1B JBrowse link 9 7,845,697 7,902,270 RGD:1600115
G Terf2ip TERF2 interacting protein JBrowse link 19 44,231,317 44,238,406 RGD:1600115
RGD:1624291
negative regulation of double-strand break repair via homologous recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cgas cyclic GMP-AMP synthase JBrowse link 8 85,789,515 85,804,008 RGD:1624291
RGD:13792537
G Fancb FA complementation group B JBrowse link X 31,124,018 31,140,790 RGD:1624291
RGD:13792537
G Fbh1 F-box DNA helicase 1 JBrowse link 17 70,399,093 70,437,151 RGD:1624291
G Helb DNA helicase B JBrowse link 7 64,860,641 64,888,146 RGD:1624291
RGD:13792537
G Klhl15 kelch-like family member 15 JBrowse link X 63,342,277 63,390,915 RGD:1624291
G Mad2l2 mitotic arrest deficient 2 like 2 JBrowse link 5 164,943,183 164,956,255 RGD:1624291
G Parpbp PARP1 binding protein JBrowse link 7 28,654,707 28,724,412 RGD:1624291
RGD:1600115
G Polq DNA polymerase theta JBrowse link 11 66,585,860 66,695,369 RGD:1624291
G Radx RPA1 related single stranded DNA binding protein, X-linked JBrowse link X 110,670,037 110,782,420 RGD:1624291
RGD:1600115
G Recql5 RecQ like helicase 5 JBrowse link 10 104,443,735 104,482,889 RGD:1624291
G Rif1 replication timing regulatory factor 1 JBrowse link 3 37,599,540 37,648,818 RGD:1624291
G Rmi2 RecQ mediated genome instability 2 JBrowse link 10 4,904,458 4,910,339 RGD:13792537
G Shld1 shieldin complex subunit 1 JBrowse link 3 125,318,682 125,396,705 RGD:1624291
RGD:13792537
G Shld2 shieldin complex subunit 2 JBrowse link 16 10,570,307 10,661,528 RGD:1624291
G Smchd1 structural maintenance of chromosomes flexible hinge domain containing 1 JBrowse link 9 119,675,750 119,818,620 RGD:1624291
G Tp53bp1 tumor protein p53 binding protein 1 JBrowse link 3 113,160,030 113,259,701 RGD:1624291
G Ubqln4 ubiquilin 4 JBrowse link 2 187,915,701 187,931,035 RGD:1624291
negative regulation of isotype switching term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Parp3 poly (ADP-ribose) polymerase family, member 3 JBrowse link 8 115,173,440 115,179,543 RGD:1624291
negative regulation of isotype switching to IgA isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Da2-19 uncharacterized LOC302729 JBrowse link X 48,196,789 48,213,506 RGD:1600115
G Thoc1 THO complex 1 JBrowse link 18 1,142,540 1,177,084 RGD:1624291
negative regulation of isotype switching to IgE isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bcl6 BCL6, transcription repressor JBrowse link 11 80,255,790 80,279,075 RGD:1624291
G Foxp3 forkhead box P3 JBrowse link X 15,753,175 15,768,648 RGD:1624291
G Ndfip1 Nedd4 family interacting protein 1 JBrowse link 18 31,574,759 31,625,286 RGD:1624291
negative regulation of mitotic recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ankle1 ankyrin repeat and LEM domain containing 1 JBrowse link 16 19,799,943 19,826,057 RGD:1624291
G Blm BLM RecQ like helicase JBrowse link 1 142,246,773 142,332,616 RGD:1624291
G Mlh1 mutL homolog 1 JBrowse link 8 119,486,655 119,523,716 RGD:1624291
RGD:1600115
negative regulation of telomere maintenance via recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Terf2 telomeric repeat binding factor 2 JBrowse link 19 39,271,992 39,301,506 RGD:1624291
RGD:13792537
positive regulation of double-strand break repair via homologous recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Actr2 actin related protein 2 JBrowse link 14 104,338,486 104,375,840 RGD:1600115
RGD:1624291
G Arid2 AT-rich interaction domain 2 JBrowse link 7 137,680,564 137,798,329 RGD:1600115
RGD:1624291
G Blm BLM RecQ like helicase JBrowse link 1 142,246,773 142,332,616 RGD:1624291
G Ercc6 ERCC excision repair 6, chromatin remodeling factor JBrowse link 16 8,734,028 8,804,610 RGD:1624291
G Fancb FA complementation group B JBrowse link X 31,124,018 31,140,790 RGD:1624291
RGD:13792537
G Fus FUS RNA binding protein JBrowse link 1 199,412,805 199,426,705 RGD:1624291
G Mms19 MMS19 homolog, cytosolic iron-sulfur assembly component JBrowse link 1 261,191,646 261,229,070 RGD:1624291
G Mrnip MRN complex interacting protein JBrowse link 10 35,680,687 35,704,685 RGD:1624291
G Parp1 poly (ADP-ribose) polymerase 1 JBrowse link 13 98,857,255 98,889,444 RGD:1600115
RGD:1624291
G Timeless timeless circadian regulator JBrowse link 7 2,643,288 2,667,329 RGD:1600115
RGD:1624291
G Was WASP actin nucleation promoting factor JBrowse link X 15,155,246 15,164,099 RGD:1624291
G Wrap53 WD repeat containing, antisense to TP53 JBrowse link 10 56,169,024 56,185,800 RGD:1600115
RGD:1624291
positive regulation of interleukin-4-dependent isotype switching to IgE isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Tnfsf4 TNF superfamily member 4 JBrowse link 13 79,269,973 79,293,775 RGD:1624291
positive regulation of isotype switching term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Exosc3 exosome component 3 JBrowse link 5 60,866,498 60,871,734 RGD:1624291
G Exosc6 exosome component 6 JBrowse link 19 43,190,879 43,193,164 RGD:1624291
G Hmces 5-hydroxymethylcytosine binding, ES cell specific JBrowse link 4 119,841,088 119,864,115 RGD:1600115
RGD:1624291
G Kmt5b lysine methyltransferase 5B JBrowse link 1 219,000,844 219,050,211 RGD:1600115
RGD:1624291
G Kmt5c lysine methyltransferase 5C JBrowse link 1 72,666,662 72,674,271 RGD:1600115
RGD:1624291
G Mad2l2 mitotic arrest deficient 2 like 2 JBrowse link 5 164,943,183 164,956,255 RGD:1624291
G Paxip1 PAX interacting protein 1 JBrowse link 4 3,956,931 4,008,326 RGD:1624291
G Rif1 replication timing regulatory factor 1 JBrowse link 3 37,599,540 37,648,818 RGD:1624291
G Shld1 shieldin complex subunit 1 JBrowse link 3 125,318,682 125,396,705 RGD:1624291
RGD:13792537
G Shld2 shieldin complex subunit 2 JBrowse link 16 10,570,307 10,661,528 RGD:1624291
G Tfrc transferrin receptor JBrowse link 11 71,397,423 71,419,263 RGD:1624291
RGD:1600115
G Tp53bp1 tumor protein p53 binding protein 1 JBrowse link 3 113,160,030 113,259,701 RGD:1624291
positive regulation of isotype switching to IgA isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mlh1 mutL homolog 1 JBrowse link 8 119,486,655 119,523,716 RGD:1600115
RGD:1624291
G Msh2 mutS homolog 2 JBrowse link 6 11,215,951 11,274,916 RGD:1600115
RGD:1624291
G Nsd2 nuclear receptor binding SET domain protein 2 JBrowse link 14 82,119,210 82,196,501 RGD:1624291
G Pms2 PMS1 homolog 2, mismatch repair system component JBrowse link 12 12,714,394 12,738,654 RGD:1624291
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:1624291
RGD:1600115
G Tnfsf13 TNF superfamily member 13 JBrowse link 10 56,286,964 56,290,680 RGD:1624291
positive regulation of isotype switching to IgE isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Clcf1 cardiotrophin-like cytokine factor 1 JBrowse link 1 219,468,866 219,472,445 RGD:1624291
G Il4 interleukin 4 JBrowse link 10 38,963,979 38,969,531 RGD:1624291
G Stat6 signal transducer and activator of transcription 6 JBrowse link 7 70,946,228 70,963,542 RGD:1624291
positive regulation of isotype switching to IgG isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atad5 ATPase family, AAA domain containing 5 JBrowse link 10 67,427,042 67,475,825 RGD:1624291
G Cd28 Cd28 molecule JBrowse link 9 67,546,408 67,573,858 RGD:1624291
RGD:1600115
G Cd40 CD40 molecule JBrowse link 3 161,519,789 161,534,943 RGD:1624291
G Ifng interferon gamma JBrowse link 7 61,337,383 61,341,419 RGD:1624291
G Il2 interleukin 2 JBrowse link 2 123,847,150 123,851,854 RGD:1624291
G Il4 interleukin 4 JBrowse link 10 38,963,979 38,969,531 RGD:1624291
G Mlh1 mutL homolog 1 JBrowse link 8 119,486,655 119,523,716 RGD:1600115
RGD:1624291
G Msh2 mutS homolog 2 JBrowse link 6 11,215,951 11,274,916 RGD:1600115
RGD:1624291
G Pagr1 Paxip1-associated glutamate-rich protein 1 JBrowse link 1 198,448,790 198,451,078 RGD:1624291
G Paxip1 PAX interacting protein 1 JBrowse link 4 3,956,931 4,008,326 RGD:1624291
G Pms2 PMS1 homolog 2, mismatch repair system component JBrowse link 12 12,714,394 12,738,654 RGD:1624291
G Ptprc protein tyrosine phosphatase, receptor type, C JBrowse link 13 55,061,561 55,174,150 RGD:1624291
G Tbx21 T-box transcription factor 21 JBrowse link 10 85,032,799 85,049,331 RGD:1624291
positive regulation of mitotic recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ercc2 ERCC excision repair 2, TFIIH core complex helicase subunit JBrowse link 1 80,293,574 80,307,334 RGD:13792537
positive regulation of reciprocal meiotic recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Prdm9 PR/SET domain 9 JBrowse link 1 57,533,602 57,555,155 RGD:1624291
RGD:13792537
G Ube2b ubiquitin-conjugating enzyme E2B JBrowse link 10 37,439,947 37,454,867 RGD:1624291
positive regulation of strand invasion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Wrn WRN RecQ like helicase JBrowse link 16 62,483,773 62,619,018 RGD:1624291
regulation of double-strand break repair via homologous recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Chek1 checkpoint kinase 1 JBrowse link 8 39,181,162 39,201,588 RGD:1624291
RGD:1600115
G Fign fidgetin, microtubule severing factor JBrowse link 3 49,992,250 50,120,601 RGD:13792537
G Fignl1 fidgetin-like 1 JBrowse link 14 91,895,902 91,904,474 RGD:1624291
RGD:13792537
RGD:1600115
G Kdm1a lysine demethylase 1A JBrowse link 5 154,909,003 154,965,171 RGD:1624291
G Ppp4c protein phosphatase 4, catalytic subunit JBrowse link 1 198,219,012 198,225,775 RGD:1600115
RGD:1624291
G Ppp4r2 protein phosphatase 4, regulatory subunit 2 JBrowse link 4 133,285,552 133,323,755 RGD:1624291
G Rad51 RAD51 recombinase JBrowse link 3 110,918,240 110,942,920 RGD:1624291
G Rad51ap1 RAD51 associated protein 1 JBrowse link 4 159,469,803 159,482,869 RGD:1624291
G Rpa2 replication protein A2 JBrowse link 5 150,957,041 150,967,597 RGD:1624291
RGD:1600115
G Rtel1 regulator of telomere elongation helicase 1 JBrowse link 3 176,818,012 176,856,531 RGD:1624291
RGD:13792537
RGD:1600115
G Setd2 SET domain containing 2, histone lysine methyltransferase JBrowse link 8 118,802,478 118,888,224 RGD:1624291
G Sirt6 sirtuin 6 JBrowse link 7 10,937,622 10,943,048 RGD:1624291
G Spidr scaffold protein involved in DNA repair JBrowse link 11 89,009,931 89,260,361 RGD:1624291
G Terf2ip TERF2 interacting protein JBrowse link 19 44,231,317 44,238,406 RGD:1624291
RGD:1600115
G Tex15 testis expressed 15, meiosis and synapsis associated JBrowse link 16 62,313,284 62,373,288 RGD:1624291
G Usp51 ubiquitin specific peptidase 51 JBrowse link X 19,268,352 19,273,753 RGD:1624291
G Zfp365 zinc finger protein 365 JBrowse link 20 22,060,160 22,083,766 RGD:1624291
RGD:1600115
regulation of isotype switching term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aplf aprataxin and PNKP like factor JBrowse link 4 119,514,822 119,568,764 RGD:1624291
G Mir181b1 microRNA 181b-1 JBrowse link 13 54,952,903 54,953,012 RGD:1624291
G Mir181b2 microRNA 181b-2 JBrowse link 3 23,151,455 23,151,542 RGD:1624291
G Supt6h SPT6 homolog, histone chaperone and transcription elongation factor JBrowse link 10 65,470,470 65,507,581 RGD:1624291
regulation of isotype switching to IgG isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Foxp3 forkhead box P3 JBrowse link X 15,753,175 15,768,648 RGD:1624291
G Il27ra interleukin 27 receptor subunit alpha JBrowse link 19 25,151,835 25,163,995 RGD:1624291
G Ndfip1 Nedd4 family interacting protein 1 JBrowse link 18 31,574,759 31,625,286 RGD:1624291
regulation of mitotic recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ercc2 ERCC excision repair 2, TFIIH core complex helicase subunit JBrowse link 1 80,293,574 80,307,334 RGD:13792537
G Rad50 RAD50 double strand break repair protein JBrowse link 10 39,002,130 39,054,042 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19439
    metabolic process 11641
      regulation of metabolic process 6582
        regulation of macromolecule metabolic process 6057
          regulation of DNA metabolic process 384
            regulation of DNA recombination 107
              negative regulation of DNA recombination + 47
              positive regulation of DNA recombination + 46
              regulation of DNA recombination at centromere + 0
              regulation of DNA recombination at telomere + 3
              regulation of double-strand break repair via homologous recombination + 45
              regulation of isotype switching + 41
              regulation of mitotic recombination + 6
              regulation of reciprocal meiotic recombination + 2
              regulation of single-strand break repair via homologous recombination + 0
              regulation of strand invasion + 1
              regulation of transposition, DNA-mediated + 0
Path 2
Term Annotations click to browse term
  biological_process 19439
    metabolic process 11641
      cellular metabolic process 10644
        cellular aromatic compound metabolic process 5507
          nucleobase-containing compound metabolic process 5278
            nucleic acid metabolic process 4788
              DNA metabolic process 885
                regulation of DNA metabolic process 384
                  regulation of DNA recombination 107
                    negative regulation of DNA recombination + 47
                    positive regulation of DNA recombination + 46
                    regulation of DNA recombination at centromere + 0
                    regulation of DNA recombination at telomere + 3
                    regulation of double-strand break repair via homologous recombination + 45
                    regulation of isotype switching + 41
                    regulation of mitotic recombination + 6
                    regulation of reciprocal meiotic recombination + 2
                    regulation of single-strand break repair via homologous recombination + 0
                    regulation of strand invasion + 1
                    regulation of transposition, DNA-mediated + 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.