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Term:SAGA complex
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Accession:GO:0000124 term browser browse the term
Definition:A SAGA-type histone acetyltransferase complex that contains Spt8 (in budding yeast) or a homolog thereof; additional polypeptides include Spt group, consisting of Spt7, Spt3, and Spt20/Ada5, which interact with the TATA-binding protein (TBP); the Ada group, consisting of Ada1, Ada2, Ada3, Ada4/Gcn5, and Ada5/Spt20, which is functionally linked to the nucleosomal HAT activity; Tra1, an ATM/PI-3 kinase-related protein that targets DNA-bound activators for recruitment to promoters; the TBP-associated factor (TAF) proteins, consisting of Taf5, Taf6, Taf9, Taf10, and Taf12, which mediate nucleosomal HAT activity and are thought to help recruit the basal transcription machinery; the ubiquitin specifc protease Ubp-8.
Synonyms:exact_synonym: Spt-Ada-Gcn5-acetyltransferase complex

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SAGA complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atxn7l3 ataxin 7-like 3 JBrowse link 10 90,234,749 90,241,757 RGD:1624291
G Eny2 ENY2, transcription and export complex 2 subunit JBrowse link 7 83,348,656 83,358,430 RGD:13792537
G Sgf29 SAGA complex associated factor 29 JBrowse link 1 198,066,974 198,100,494 RGD:1600115
G Supt20h SPT20 homolog, SAGA complex component JBrowse link 2 143,892,609 143,925,733 RGD:1600115
G Tada1 transcriptional adaptor 1 JBrowse link 13 84,588,587 84,602,542 RGD:13792537
G Tada3 transcriptional adaptor 3 JBrowse link 4 145,318,417 145,330,291 RGD:13792537
G Taf12 TATA-box binding protein associated factor 12 JBrowse link 5 150,459,701 150,476,521 RGD:1600115
G Taf6 TATA-box binding protein associated factor 6 JBrowse link 12 19,320,269 19,328,706 RGD:1600115
G Taf6l TATA-box binding protein associated factor 6 like JBrowse link 1 224,974,238 224,986,819 RGD:13792537
G Taf9 TATA-box binding protein associated factor 9 JBrowse link 2 30,664,407 30,668,414 RGD:13792537
G Taf9b TATA-box binding protein associated factor 9b JBrowse link X 77,281,234 77,295,238 RGD:13792537
G Usp22 ubiquitin specific peptidase 22 JBrowse link 10 47,429,201 47,453,298 RGD:1624291

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Path 1
Term Annotations click to browse term
  cellular_component 19951
    protein-containing complex 5828
      catalytic complex 1451
        peptidase complex 100
          SAGA complex 12
Path 2
Term Annotations click to browse term
  cellular_component 19951
    cellular anatomical entity 19598
      organelle 12670
        intracellular organelle 12137
          intracellular membrane-bounded organelle 10066
            nucleus 6843
              nuclear lumen 4008
                nucleoplasm 3379
                  histone acetyltransferase complex 90
                    SAGA-type complex 26
                      SAGA complex 12
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.