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ONTOLOGY REPORT - ANNOTATIONS


Term:protein phosphatase type 2A complex
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Accession:GO:0000159 term browser browse the term
Definition:A protein complex that has protein serine/threonine phosphatase activity that is polycation-stimulated (PCS), being directly stimulated by protamine, polylysine, or histone H1; it constitutes a subclass of several enzymes activated by different histones and polylysine, and consists of catalytic, scaffolding, and regulatory subunits. The catalytic and scaffolding subunits form the core enzyme, and the holoenzyme also includes the regulatory subunit.
Synonyms:related_synonym: protein phosphatase 2 complex


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protein phosphatase type 2A complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ier5 immediate early response 5 JBrowse link 13 72,742,210 72,744,302 RGD:1624291
G Nkd1 NKD inhibitor of WNT signaling pathway 1 JBrowse link 19 19,434,720 19,509,087 RGD:1624291
G Ppp2ca protein phosphatase 2 catalytic subunit alpha JBrowse link 10 37,534,449 37,554,861 RGD:1624291
RGD:8553977
G Ppp2cb protein phosphatase 2 catalytic subunit beta JBrowse link 16 62,273,276 62,294,767 RGD:1624291
G Ppp2r1a protein phosphatase 2 scaffold subunit A alpha JBrowse link 1 60,717,386 60,736,629 RGD:1624291
RGD:13792537
G Ppp2r1b protein phosphatase 2 scaffold subunit A beta JBrowse link 8 55,279,278 55,311,768 RGD:13792537
G Ppp2r2a protein phosphatase 2, regulatory subunit B, alpha JBrowse link 15 43,673,958 43,733,182 RGD:1624291
RGD:13792537
G Ppp2r2b protein phosphatase 2, regulatory subunit B, beta JBrowse link 18 36,985,709 37,421,383 RGD:2314541
RGD:13792537
RGD:1600115
G Ppp2r2c protein phosphatase 2, regulatory subunit B, gamma JBrowse link 14 78,679,214 78,763,175 RGD:13792537
RGD:1600115
G Ppp2r2d protein phosphatase 2, regulatory subunit B, delta JBrowse link 1 211,205,903 211,240,216 RGD:1600115
RGD:13792537
G Ppp2r3a protein phosphatase 2, regulatory subunit B'', alpha JBrowse link 8 109,481,352 109,621,462 RGD:1624291
RGD:13792537
G Ppp2r3b protein phosphatase 2, regulatory subunit B'', beta JBrowse link 14 1,469,748 1,476,353 RGD:1624291
RGD:13792537
G Ppp2r5a protein phosphatase 2, regulatory subunit B', alpha JBrowse link 13 110,033,550 110,077,946 RGD:1624291
RGD:13792537
G Ppp2r5b protein phosphatase 2, regulatory subunit B', beta JBrowse link 1 221,597,294 221,605,467 RGD:13792537
G Ppp2r5c protein phosphatase 2, regulatory subunit B', gamma JBrowse link 6 134,804,128 134,941,912 RGD:1624291
RGD:13792537
G Ppp2r5d protein phosphatase 2, regulatory subunit B', delta JBrowse link 9 16,580,995 16,610,425 RGD:1600115
G Ppp2r5e protein phosphatase 2 regulatory subunit B', epsilon JBrowse link 6 98,417,974 98,567,016 RGD:13792537
G Ptpa protein phosphatase 2 phosphatase activator JBrowse link 3 8,982,122 9,012,585 RGD:1624291
RGD:13792537

Term paths to the root
Path 1
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  cellular_component 19949
    intracellular 13934
      protein phosphatase type 2A complex 18
Path 2
Term Annotations click to browse term
  cellular_component 19949
    protein-containing complex 5829
      catalytic complex 1451
        phosphatase complex 49
          protein serine/threonine phosphatase complex 48
            protein phosphatase type 2A complex 18
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.