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ONTOLOGY REPORT - ANNOTATIONS


Term:activation of MAPKKK activity
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Accession:GO:0000185 term browser browse the term
Definition:Any process that initiates the activity of the inactive enzyme MAP kinase kinase kinase (MAPKKK).
Synonyms:exact_synonym: activation of MAP kinase kinase kinase;   activation of MAP3K activity
 narrow_synonym: activation of MAPKKK activity during sporulation
 broad_synonym: positive regulation of MAP kinase kinase kinase activity;   positive regulation of MAPKKK activity
 only_in_taxon: NCBITaxon:2759 ! Eukaryota


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activation of MAPKKK activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G App amyloid beta precursor protein JBrowse link 11 24,425,013 24,641,872 RGD:1624291
G Dab2ip DAB2 interacting protein JBrowse link 3 14,889,263 15,060,286 RGD:1600115
RGD:1624291
G Gadd45a growth arrest and DNA-damage-inducible, alpha JBrowse link 4 97,782,512 97,784,814 RGD:1600115
RGD:13792537
RGD:1624291
G Gadd45b growth arrest and DNA-damage-inducible, beta JBrowse link 7 11,646,283 11,648,338 RGD:1624291
RGD:13792537
G Gadd45g growth arrest and DNA-damage-inducible, gamma JBrowse link 17 13,391,474 13,393,219 RGD:1624291
RGD:13792537
G Grm5 glutamate metabotropic receptor 5 JBrowse link 1 151,207,846 151,785,038 RGD:8554618
G Ksr1 kinase suppressor of ras 1 JBrowse link 10 66,323,704 66,342,469 RGD:1624291
RGD:1600115
G Map4k1 mitogen activated protein kinase kinase kinase kinase 1 JBrowse link 1 87,937,126 87,959,514 RGD:1600115
G Map4k2 mitogen activated protein kinase kinase kinase kinase 2 JBrowse link 1 221,710,622 221,726,274 RGD:1600115
G Map4k3 mitogen-activated protein kinase kinase kinase kinase 3 JBrowse link 6 3,276,732 3,444,519 RGD:1600115
G Map4k5 mitogen-activated protein kinase kinase kinase kinase 5 JBrowse link 6 92,136,242 92,229,578 RGD:1600115
G Tab1 TGF-beta activated kinase 1/MAP3K7 binding protein 1 JBrowse link 7 121,350,953 121,382,100 RGD:1624291
RGD:1600115
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:1624291
G Traf7 TNF receptor associated factor 7 JBrowse link 10 13,874,444 13,893,090 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19245
    cellular process 17125
      signal transduction 6837
        signal transduction by protein phosphorylation 870
          MAPK cascade 850
            positive regulation of MAPK cascade 567
              positive regulation of MAP kinase activity 237
                activation of MAPKKK activity 14
                  activation of JNKKK activity 0
                  activation of MAPKKK activity involved in cell wall organization or biogenesis 0
                  activation of MAPKKK activity involved in conjugation with cellular fusion 0
                  activation of MAPKKK activity involved in osmosensory signaling pathway 0
Path 2
Term Annotations click to browse term
  biological_process 19245
    metabolic process 11438
      organic substance metabolic process 10836
        macromolecule metabolic process 9317
          cellular macromolecule metabolic process 8037
            cellular protein metabolic process 5268
              cellular protein modification process 3844
                regulation of protein modification process 1917
                  regulation of protein phosphorylation 1504
                    regulation of protein kinase activity 754
                      regulation of protein serine/threonine kinase activity 487
                        positive regulation of protein serine/threonine kinase activity 320
                          positive regulation of MAP kinase activity 237
                            activation of MAPKKK activity 14
                              activation of JNKKK activity 0
                              activation of MAPKKK activity involved in cell wall organization or biogenesis 0
                              activation of MAPKKK activity involved in conjugation with cellular fusion 0
                              activation of MAPKKK activity involved in osmosensory signaling pathway 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.