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ONTOLOGY REPORT - ANNOTATIONS


Term:activation of MAPK activity
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Accession:GO:0000187 term browser browse the term
Definition:The initiation of the activity of the inactive enzyme MAP kinase (MAPK).
Synonyms:exact_synonym: MAPK activation;   activation of MAP kinase
 narrow_synonym: activation of MAPK activity during sporulation


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activation of MAPK activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AGT angiotensinogen JBrowse link 4 8,681,192 8,694,059 RGD:13508589
G ALK ALK receptor tyrosine kinase JBrowse link 17 23,010,308 23,688,841 RGD:13508589
G AVPI1 arginine vasopressin induced 1 JBrowse link 28 10,922,710 10,944,182 RGD:13508589
G C1QTNF2 C1q and TNF related 2 JBrowse link 4 50,352,245 50,372,412 RGD:13508589
G CD81 CD81 molecule JBrowse link 18 46,466,484 46,474,236 RGD:13508589
G CRKL CRK like proto-oncogene, adaptor protein JBrowse link 26 30,542,276 30,582,479 RGD:13508589
G CSPG4 chondroitin sulfate proteoglycan 4 JBrowse link 30 38,465,486 38,498,365 RGD:13508589
G CXCL17 C-X-C motif chemokine ligand 17 JBrowse link 1 111,969,808 111,986,767 RGD:13508589
G EGF epidermal growth factor JBrowse link 32 30,073,541 30,166,904 RGD:13508589
G EPGN epithelial mitogen JBrowse link 13 62,803,595 62,811,581 RGD:13508589
G ERP29 endoplasmic reticulum protein 29 JBrowse link 26 9,608,352 9,616,711 RGD:13508589
G FGF1 fibroblast growth factor 1 JBrowse link 2 37,467,431 37,554,770 RGD:13508589
G FGF10 fibroblast growth factor 10 JBrowse link 4 65,851,130 65,930,944 RGD:13508589
G FRS2 fibroblast growth factor receptor substrate 2 JBrowse link 10 11,445,843 11,552,325 RGD:13508589
G GDF15 growth differentiation factor 15 JBrowse link 20 44,633,131 44,636,842 RGD:13508589
G GFRAL GDNF family receptor alpha like JBrowse link 12 22,646,015 22,702,428 RGD:13508589
G GHRL ghrelin and obestatin prepropeptide JBrowse link 20 8,092,921 8,097,512 RGD:13508589
G GRM1 glutamate metabotropic receptor 1 JBrowse link 1 37,205,817 37,600,048 RGD:13508589
G GRM4 glutamate metabotropic receptor 4 JBrowse link 12 3,346,395 3,459,722 RGD:13508589
G HGF hepatocyte growth factor JBrowse link 18 21,329,688 21,410,257 RGD:13508589
G INSR insulin receptor JBrowse link 20 52,017,261 52,136,061 RGD:13508589
G KARS1 lysyl-tRNA synthetase 1 JBrowse link 5 75,172,976 75,188,197 RGD:13508589
G KIT KIT proto-oncogene, receptor tyrosine kinase JBrowse link 13 47,108,442 47,190,935 RGD:13508589
G LPAR1 lysophosphatidic acid receptor 1 JBrowse link 11 65,690,806 65,822,166 RGD:13508589
G LPAR3 lysophosphatidic acid receptor 3 JBrowse link 6 63,035,332 63,114,697 RGD:13508589
G LRRK2 leucine rich repeat kinase 2 JBrowse link 27 13,282,824 13,420,917 RGD:13508589
G MAP2K1 mitogen-activated protein kinase kinase 1 JBrowse link 30 30,683,192 30,760,479 RGD:13508589
G MAP2K2 mitogen-activated protein kinase kinase 2 JBrowse link 20 55,465,460 55,487,629 RGD:13508589
G MAP2K3 mitogen-activated protein kinase kinase 3 JBrowse link 5 42,732,751 42,762,420 RGD:13508589
G MAP2K4 mitogen-activated protein kinase kinase 4 JBrowse link 5 36,142,610 36,243,673 RGD:13508589
G MAP2K5 mitogen-activated protein kinase kinase 5 JBrowse link 30 31,665,032 31,920,792 RGD:13508589
G MAP2K6 mitogen-activated protein kinase kinase 6 JBrowse link 9 15,840,714 15,962,400 RGD:13508589
G MAP2K7 mitogen-activated protein kinase kinase 7 JBrowse link 20 52,594,450 52,604,236 RGD:13508589
G MAP3K5 mitogen-activated protein kinase kinase kinase 5 JBrowse link 1 29,107,813 29,306,437 RGD:13508589
G MAP3K7 mitogen-activated protein kinase kinase kinase 7 JBrowse link 12 49,669,849 49,740,039 RGD:13508589
G MAPK1 mitogen-activated protein kinase 1 JBrowse link 26 31,013,607 31,132,998 RGD:13508589
G MUC20 mucin 20, cell surface associated JBrowse link 33 29,044,104 29,055,583 RGD:13508589
G NRG1 neuregulin 1 JBrowse link 16 31,697,958 32,771,888 RGD:13508589
G NTF3 neurotrophin 3 JBrowse link 27 39,383,017 39,454,613 RGD:13508589
G P2RX7 purinergic receptor P2X 7 JBrowse link 26 7,928,863 7,983,956 RGD:13508589
G PAK3 p21 (RAC1) activated kinase 3 JBrowse link X 84,074,146 84,335,699 RGD:13508589
G PDE6G phosphodiesterase 6G JBrowse link 9 525,123 529,406 RGD:13508589
G PDE6H phosphodiesterase 6H JBrowse link 27 31,640,731 31,664,494 RGD:13508589
G PLCE1 phospholipase C epsilon 1 JBrowse link 28 8,209,707 8,484,427 RGD:13508589
G PRDX2 peroxiredoxin 2 JBrowse link 20 49,352,271 49,356,755 RGD:13508589
G PROK1 prokineticin 1 JBrowse link 6 41,544,966 41,550,793 RGD:13508589
G PTPN11 protein tyrosine phosphatase non-receptor type 11 JBrowse link 26 9,989,218 10,072,245 RGD:13508589
G SBK3 SH3 domain binding kinase family member 3 JBrowse link 1 102,177,147 102,189,415 RGD:13508589
G SHC1 SHC adaptor protein 1 JBrowse link 7 42,501,829 42,509,613 RGD:13508589
G SHC2 SHC adaptor protein 2 JBrowse link 20 58,001,442 58,023,201 RGD:13508589
G SOD1 superoxide dismutase 1 JBrowse link 31 26,540,291 26,544,212 RGD:13508589
G THBS1 thrombospondin 1 JBrowse link 30 6,770,212 6,786,875 RGD:13508589
G TLR4 toll like receptor 4 JBrowse link 11 71,356,390 71,367,166 RGD:13508589
G TNF tumor necrosis factor JBrowse link 12 1,074,561 1,076,425 RGD:13508589
G WNT5A Wnt family member 5A JBrowse link 20 34,756,430 34,790,937 RGD:13508589
activation of JUN kinase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CD40LG CD40 ligand JBrowse link X 107,001,421 107,023,007 RGD:13508589
G ERCC6 ERCC excision repair 6, chromatin remodeling factor JBrowse link 28 1,358,383 1,432,276 RGD:13508589
G ERN1 endoplasmic reticulum to nucleus signaling 1 JBrowse link 9 11,930,614 12,006,724 RGD:13508589
G ERN2 endoplasmic reticulum to nucleus signaling 2 JBrowse link 6 22,150,275 22,165,382 RGD:13508589
G MAP2K4 mitogen-activated protein kinase kinase 4 JBrowse link 5 36,142,610 36,243,673 RGD:13508589
G MAP2K7 mitogen-activated protein kinase kinase 7 JBrowse link 20 52,594,450 52,604,236 RGD:13508589
G MAP3K10 mitogen-activated protein kinase kinase kinase 10 JBrowse link 1 113,422,239 113,435,979 RGD:13508589
G MAP3K11 mitogen-activated protein kinase kinase kinase 11 JBrowse link 18 51,593,641 51,609,245 RGD:13508589
G MAP3K12 mitogen-activated protein kinase kinase kinase 12 JBrowse link 27 1,721,484 1,736,204 RGD:13508589
G MAP3K13 mitogen-activated protein kinase kinase kinase 13 JBrowse link 34 18,081,158 18,252,800 RGD:13508589
G MAP3K9 mitogen-activated protein kinase kinase kinase 9 JBrowse link 8 44,435,714 44,509,528 RGD:13508589
G MAP4K1 mitogen-activated protein kinase kinase kinase kinase 1 JBrowse link 1 114,444,231 114,461,254 RGD:13508589
G MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2 JBrowse link 18 52,353,606 52,367,065 RGD:13508589
G MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3 JBrowse link 6 39,132,746 39,179,427 RGD:13508589
G MUL1 mitochondrial E3 ubiquitin protein ligase 1 JBrowse link 2 78,394,013 78,402,032 RGD:13508589
G PTPN1 protein tyrosine phosphatase non-receptor type 1 JBrowse link 24 36,936,469 37,010,929 RGD:13508589
G RIPK1 receptor interacting serine/threonine kinase 1 JBrowse link 35 3,367,796 3,407,631 RGD:13508589
G SPAG9 sperm associated antigen 9 JBrowse link 9 26,820,381 26,966,315 RGD:13508589
G TNFSF11 TNF superfamily member 11 JBrowse link 22 8,226,931 8,257,926 RGD:13508589
G WNT5A Wnt family member 5A JBrowse link 20 34,756,430 34,790,937 RGD:13508589

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 13644
    cellular process 12002
      signal transduction 4078
        signal transduction by protein phosphorylation 500
          MAPK cascade 477
            positive regulation of MAPK cascade 324
              positive regulation of MAP kinase activity 140
                activation of MAPK activity 72
                  activation of JUN kinase activity 20
                  activation of MAPK activity by adrenergic receptor signaling pathway 0
                  activation of MAPK activity involved in cell wall organization or biogenesis 0
                  activation of MAPK activity involved in conjugation with cellular fusion 0
                  activation of MAPK activity involved in osmosensory signaling pathway 0
Path 2
Term Annotations click to browse term
  biological_process 13644
    metabolic process 8513
      organic substance metabolic process 8046
        macromolecule metabolic process 6873
          cellular macromolecule metabolic process 5920
            cellular protein metabolic process 3671
              cellular protein modification process 2850
                regulation of protein modification process 1196
                  regulation of protein phosphorylation 918
                    regulation of protein kinase activity 482
                      regulation of protein serine/threonine kinase activity 310
                        positive regulation of protein serine/threonine kinase activity 187
                          positive regulation of MAP kinase activity 140
                            activation of MAPK activity 72
                              activation of JUN kinase activity 20
                              activation of MAPK activity by adrenergic receptor signaling pathway 0
                              activation of MAPK activity involved in cell wall organization or biogenesis 0
                              activation of MAPK activity involved in conjugation with cellular fusion 0
                              activation of MAPK activity involved in osmosensory signaling pathway 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.