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ONTOLOGY REPORT - ANNOTATIONS


Term:activation of MAPK activity
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Accession:GO:0000187 term browser browse the term
Definition:The initiation of the activity of the inactive enzyme MAP kinase (MAPK).
Synonyms:exact_synonym: MAPK activation;   activation of MAP kinase
 narrow_synonym: activation of MAPK activity during sporulation


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activation of MAPK activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adra2b adrenergic receptor, alpha 2b JBrowse link 2 127,363,179 127,367,221 RGD:2290270
G Agt angiotensinogen (serpin peptidase inhibitor, clade A, member 8) JBrowse link 8 124,556,587 124,569,706 RGD:2290270
G Alk anaplastic lymphoma kinase JBrowse link 17 71,868,988 72,604,702 RGD:2290270
G App amyloid beta (A4) precursor protein JBrowse link 16 84,952,666 85,175,255 RGD:2290270
G Arrb1 arrestin, beta 1 JBrowse link 7 99,535,147 99,606,772 RGD:2290270
G Avpi1 arginine vasopressin-induced 1 JBrowse link 19 42,123,275 42,128,993 RGD:2290270
G Bmp2 bone morphogenetic protein 2 JBrowse link 2 133,552,159 133,562,896 RGD:2290270
G C1qtnf2 C1q and tumor necrosis factor related protein 2 JBrowse link 11 43,474,306 43,491,525 RGD:2290270
G Cd74 CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated) JBrowse link 18 60,803,849 60,812,652 RGD:2290270
G Cd81 CD81 antigen JBrowse link 7 143,052,750 143,067,930 RGD:2290270
G Chrna7 cholinergic receptor, nicotinic, alpha polypeptide 7 JBrowse link 7 63,098,692 63,212,526 RGD:2290270
G Crkl v-crk avian sarcoma virus CT10 oncogene homolog-like JBrowse link 16 17,451,985 17,487,440 RGD:2290270
G Cspg4 chondroitin sulfate proteoglycan 4 JBrowse link 9 56,865,104 56,899,870 RGD:2290270
G Cxcl17 chemokine (C-X-C motif) ligand 17 JBrowse link 7 25,400,053 25,412,886 RGD:2290270
G Drd4 dopamine receptor D4 JBrowse link 7 141,291,974 141,296,464 RGD:2290270
G Egf epidermal growth factor JBrowse link 3 129,677,574 129,755,322 RGD:2290270
G Epgn epithelial mitogen JBrowse link 5 91,027,517 91,035,212 RGD:2290270
G Erp29 endoplasmic reticulum protein 29 JBrowse link 5 121,444,753 121,452,474 RGD:2290270
G Fcer1a Fc receptor, IgE, high affinity I, alpha polypeptide JBrowse link 1 173,221,269 173,227,232 RGD:2290270
G Fgf1 fibroblast growth factor 1 JBrowse link 18 38,838,672 38,929,470 RGD:2290270
G Fgf10 fibroblast growth factor 10 JBrowse link 13 118,714,699 118,792,573 RGD:2290270
G Frs2 fibroblast growth factor receptor substrate 2 JBrowse link 10 117,070,127 117,148,474 RGD:2290270
G Gab1 growth factor receptor bound protein 2-associated protein 1 JBrowse link 8 80,764,431 80,880,519 RGD:2290270
G Gdf15 growth differentiation factor 15 JBrowse link 8 70,629,393 70,632,470 RGD:2290270
G Gfral GDNF family receptor alpha like JBrowse link 9 76,164,102 76,213,657 RGD:2290270
G Ghr growth hormone receptor JBrowse link 15 3,317,755 3,583,352 RGD:2290270
G Ghrl ghrelin JBrowse link 6 113,716,119 113,719,911 RGD:2290270
G Gpr39 G protein-coupled receptor 39 JBrowse link 1 125,676,996 125,873,862 RGD:2290270
G Grm1 glutamate receptor, metabotropic 1 JBrowse link 10 10,686,059 11,082,382 RGD:2290270
G Grm4 glutamate receptor, metabotropic 4 JBrowse link 17 27,422,387 27,513,826 RGD:2290270
G Hgf hepatocyte growth factor JBrowse link 5 16,553,495 16,619,439 RGD:2290270
G Igf1 insulin-like growth factor 1 JBrowse link 10 87,858,265 87,937,047 RGD:2290270
G Igh-7 immunoglobulin heavy chain 7 (heavy chain of IgE) RGD:2290270
G Ighm immunoglobulin heavy constant mu JBrowse link 12 113,418,826 113,422,730 RGD:2290270
G Il1b interleukin 1 beta JBrowse link 2 129,364,569 129,371,164 RGD:2290270
G Inava innate immunity activator JBrowse link 1 136,213,522 136,234,293 RGD:2290270
G Ins1 insulin I JBrowse link 19 52,264,297 52,265,015 RGD:2290270
G Ins2 insulin II JBrowse link 7 142,678,656 142,679,726 RGD:2290270
G Insr insulin receptor JBrowse link 8 3,150,922 3,279,649 RGD:2290270
G Iqgap3 IQ motif containing GTPase activating protein 3 JBrowse link 3 88,082,002 88,121,048 RGD:2290270
G Itga1 integrin alpha 1 JBrowse link 13 114,958,079 115,101,964 RGD:2290270
G Kars lysyl-tRNA synthetase JBrowse link 8 111,993,439 112,011,354 RGD:2290270
G Kit KIT proto-oncogene receptor tyrosine kinase JBrowse link 5 75,574,987 75,656,722 RGD:2290270
G Lpar1 lysophosphatidic acid receptor 1 JBrowse link 4 58,435,252 58,554,027 RGD:2290270
G Lpar2 lysophosphatidic acid receptor 2 JBrowse link 8 69,822,565 69,831,102 RGD:2290270
G Lpar3 lysophosphatidic acid receptor 3 JBrowse link 3 146,220,961 146,286,214 RGD:2290270
G Lrrk2 leucine-rich repeat kinase 2 JBrowse link 15 91,672,791 91,816,124 RGD:2290270
G Madd MAP-kinase activating death domain JBrowse link 2 91,137,360 91,184,006 RGD:2290270
G Map2k1 mitogen-activated protein kinase kinase 1 JBrowse link 9 64,185,769 64,253,605 RGD:2290270
G Map2k2 mitogen-activated protein kinase kinase 2 JBrowse link 10 81,105,913 81,124,697 RGD:2290270
G Map2k3 mitogen-activated protein kinase kinase 3 JBrowse link 11 60,932,054 60,952,811 RGD:2290270
G Map2k4 mitogen-activated protein kinase kinase 4 JBrowse link 11 65,688,244 65,788,359 RGD:2290270
G Map2k5 mitogen-activated protein kinase kinase 5 JBrowse link 9 63,163,768 63,381,682 RGD:2290270
G Map2k6 mitogen-activated protein kinase kinase 6 JBrowse link 11 110,399,102 110,525,522 RGD:2290270
G Map2k7 mitogen-activated protein kinase kinase 7 JBrowse link 8 4,238,740 4,247,897 RGD:2290270
G Map3k11 mitogen-activated protein kinase kinase kinase 11 JBrowse link 19 5,688,411 5,702,865 RGD:2290270
G Map3k5 mitogen-activated protein kinase kinase kinase 5 JBrowse link 10 19,934,101 20,142,750 RGD:2290270
G Met met proto-oncogene JBrowse link 6 17,463,349 17,573,980 RGD:2290270
G Mos Moloney sarcoma oncogene JBrowse link 4 3,870,658 3,872,105 RGD:2290270
G Muc20 mucin 20 JBrowse link 16 32,777,419 32,797,435 RGD:2290270
G Ntf3 neurotrophin 3 JBrowse link 6 126,101,412 126,166,772 RGD:2290270
G Ntrk3 neurotrophic tyrosine kinase, receptor, type 3 JBrowse link 7 78,179,986 78,581,034 RGD:2290270
G P2rx7 purinergic receptor P2X, ligand-gated ion channel, 7 JBrowse link 5 122,643,927 122,692,336 RGD:2290270
G Pde6g phosphodiesterase 6G, cGMP-specific, rod, gamma JBrowse link 11 120,447,607 120,453,500 RGD:2290270
G Pde6h phosphodiesterase 6H, cGMP-specific, cone, gamma JBrowse link 6 136,952,218 136,963,485 RGD:2290270
G Plce1 phospholipase C, epsilon 1 JBrowse link 19 38,481,034 38,785,105 RGD:2290270
G Prdx2 peroxiredoxin 2 JBrowse link 8 84,969,622 84,974,811 RGD:2290270
G Prok1 prokineticin 1 JBrowse link 3 107,231,916 107,239,707 RGD:2290270
G Prok2 prokineticin 2 JBrowse link 6 99,711,299 99,726,392 RGD:2290270
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 JBrowse link 5 121,130,533 121,191,397 RGD:2290270
G Ptprc protein tyrosine phosphatase, receptor type, C JBrowse link 1 138,062,859 138,175,756 RGD:2290270
G Pxn paxillin JBrowse link 5 115,491,970 115,555,987 RGD:2290270
G Ret ret proto-oncogene JBrowse link 6 118,151,748 118,197,744 RGD:2290270
G Sbk2 SH3-binding domain kinase family, member 2 JBrowse link 7 4,956,134 4,964,422 RGD:2290270
G Shc1 src homology 2 domain-containing transforming protein C1 JBrowse link 3 89,418,551 89,430,029 RGD:2290270
G Shc2 SHC (Src homology 2 domain containing) transforming protein 2 JBrowse link 10 79,617,934 79,637,918 RGD:2290270
G Sod1 superoxide dismutase 1, soluble JBrowse link 16 90,220,762 90,226,333 RGD:2290270
G Spag9 sperm associated antigen 9 JBrowse link 11 93,996,046 94,126,093 RGD:2290270
G Stk39 serine/threonine kinase 39 JBrowse link 2 68,210,445 68,472,108 RGD:2290270
G Syk spleen tyrosine kinase JBrowse link 13 52,582,610 52,648,792 RGD:2290270
G Tdgf1 teratocarcinoma-derived growth factor 1 JBrowse link 9 110,939,608 110,946,158 RGD:2290270
G Tgfa transforming growth factor alpha JBrowse link 6 86,195,038 86,275,743 RGD:2290270
G Tgfb3 transforming growth factor, beta 3 JBrowse link 12 86,056,743 86,079,041 RGD:2290270
G Thbs1 thrombospondin 1 JBrowse link 2 118,111,876 118,127,133 RGD:2290270
G Tlr4 toll-like receptor 4 JBrowse link 4 66,827,551 66,846,581 RGD:2290270
G Tnf tumor necrosis factor JBrowse link 17 35,199,367 35,202,007 RGD:2290270
G Trp73 transformation related protein 73 JBrowse link 4 154,056,249 154,139,875 RGD:2290270
G Wnt5a wingless-type MMTV integration site family, member 5A JBrowse link 14 28,504,543 28,527,448 RGD:2290270
activation of JUN kinase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bcl10 B cell leukemia/lymphoma 10 JBrowse link 3 145,924,262 145,934,366 RGD:2290270
G Ccl19 chemokine (C-C motif) ligand 19 JBrowse link 4 42,754,525 42,756,518 RGD:2290270
G Ccr7 chemokine (C-C motif) receptor 7 JBrowse link 11 99,144,199 99,155,077 RGD:2290270
G Cd40lg CD40 ligand JBrowse link X 57,212,143 57,224,042 RGD:2290270
G Dab2 disabled 2, mitogen-responsive phosphoprotein JBrowse link 15 6,299,788 6,440,715 RGD:2290270
G Dab2ip disabled 2 interacting protein JBrowse link 2 35,558,446 35,730,994 RGD:2290270
G Ercc6 excision repair cross-complementing rodent repair deficiency, complementation group 6 JBrowse link 14 32,513,291 32,580,990 RGD:2290270
G Ern1 endoplasmic reticulum (ER) to nucleus signalling 1 JBrowse link 11 106,397,620 106,487,796 RGD:2290270
G Ern2 endoplasmic reticulum (ER) to nucleus signalling 2 JBrowse link 7 122,169,893 122,186,239 RGD:2290270
G Fcer1a Fc receptor, IgE, high affinity I, alpha polypeptide JBrowse link 1 173,221,269 173,227,232 RGD:2290270
G Fgd4 FYVE, RhoGEF and PH domain containing 4 JBrowse link 16 16,416,910 16,600,534 RGD:2290270
G Gab1 growth factor receptor bound protein 2-associated protein 1 JBrowse link 8 80,764,431 80,880,519 RGD:2290270
G Igh-7 immunoglobulin heavy chain 7 (heavy chain of IgE) RGD:2290270
G Ins2 insulin II JBrowse link 7 142,678,656 142,679,726 RGD:2290270
G Map2k4 mitogen-activated protein kinase kinase 4 JBrowse link 11 65,688,244 65,788,359 RGD:2290270
G Map2k7 mitogen-activated protein kinase kinase 7 JBrowse link 8 4,238,740 4,247,897 RGD:2290270
G Map3k1 mitogen-activated protein kinase kinase kinase 1 JBrowse link 13 111,746,428 111,818,269 RGD:2290270
G Map3k10 mitogen-activated protein kinase kinase kinase 10 JBrowse link 7 27,656,375 27,674,630 RGD:2290270
G Map3k11 mitogen-activated protein kinase kinase kinase 11 JBrowse link 19 5,688,411 5,702,865 RGD:2290270
G Map3k12 mitogen-activated protein kinase kinase kinase 12 JBrowse link 15 102,497,647 102,517,004 RGD:2290270
G Map3k13 mitogen-activated protein kinase kinase kinase 13 JBrowse link 16 21,824,056 21,933,439 RGD:2290270
G Map3k20 mitogen-activated protein kinase kinase kinase 20 JBrowse link 2 72,285,637 72,442,610 RGD:2290270
G Map3k21 mitogen-activated protein kinase kinase kinase 21 JBrowse link 8 125,910,450 125,947,440 RGD:2290270
G Map3k9 mitogen-activated protein kinase kinase kinase 9 JBrowse link 12 81,714,950 81,781,170 RGD:2290270
G Map4k1 mitogen-activated protein kinase kinase kinase kinase 1 JBrowse link 7 28,982,050 29,003,279 RGD:2290270
G Map4k2 mitogen-activated protein kinase kinase kinase kinase 2 JBrowse link 19 6,340,990 6,355,619 RGD:2290270
G Mapk8ip3 mitogen-activated protein kinase 8 interacting protein 3 JBrowse link 17 24,897,506 24,936,977 RGD:2290270
G Mdfi MyoD family inhibitor JBrowse link 17 47,815,328 47,834,691 RGD:2290270
G Mdfic MyoD family inhibitor domain containing JBrowse link 6 15,720,566 15,802,169 RGD:2290270
G Mul1 mitochondrial ubiquitin ligase activator of NFKB 1 JBrowse link 4 138,434,660 138,442,265 RGD:2290270
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 JBrowse link 2 167,930,750 167,979,385 RGD:2290270
G Ripk1 receptor (TNFRSF)-interacting serine-threonine kinase 1 JBrowse link 13 34,002,225 34,035,170 RGD:2290270
G Spag9 sperm associated antigen 9 JBrowse link 11 93,996,046 94,126,093 RGD:2290270
G Syk spleen tyrosine kinase JBrowse link 13 52,582,610 52,648,792 RGD:2290270
G Tirap toll-interleukin 1 receptor (TIR) domain-containing adaptor protein JBrowse link 9 35,184,391 35,200,291 RGD:2290270
G Tnfsf11 tumor necrosis factor (ligand) superfamily, member 11 JBrowse link 14 78,277,446 78,308,043 RGD:2290270
G Trf transferrin JBrowse link 9 103,208,876 103,230,286 RGD:2290270
G Wnt5a wingless-type MMTV integration site family, member 5A JBrowse link 14 28,504,543 28,527,448 RGD:2290270
G Wnt7b wingless-type MMTV integration site family, member 7B JBrowse link 15 85,535,437 85,581,821 RGD:2290270

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 23162
    cellular process 16953
      signal transduction 6230
        signal transduction by protein phosphorylation 803
          MAPK cascade 779
            positive regulation of MAPK cascade 525
              positive regulation of MAP kinase activity 225
                activation of MAPK activity 117
                  activation of JUN kinase activity 39
                  activation of MAPK activity by adrenergic receptor signaling pathway 0
                  activation of MAPK activity involved in cell wall organization or biogenesis 0
                  activation of MAPK activity involved in conjugation with cellular fusion 0
                  activation of MAPK activity involved in osmosensory signaling pathway 0
Path 2
Term Annotations click to browse term
  biological_process 23162
    metabolic process 10900
      organic substance metabolic process 10349
        macromolecule metabolic process 8877
          cellular macromolecule metabolic process 7349
            cellular protein metabolic process 4683
              cellular protein modification process 3561
                regulation of protein modification process 1834
                  regulation of protein phosphorylation 1461
                    regulation of protein kinase activity 696
                      regulation of protein serine/threonine kinase activity 448
                        positive regulation of protein serine/threonine kinase activity 293
                          positive regulation of MAP kinase activity 225
                            activation of MAPK activity 117
                              activation of JUN kinase activity 39
                              activation of MAPK activity by adrenergic receptor signaling pathway 0
                              activation of MAPK activity involved in cell wall organization or biogenesis 0
                              activation of MAPK activity involved in conjugation with cellular fusion 0
                              activation of MAPK activity involved in osmosensory signaling pathway 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.