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ONTOLOGY REPORT - ANNOTATIONS


Term:protein polyubiquitination
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Accession:GO:0000209 term browser browse the term
Definition:Addition of multiple ubiquitin groups to a protein, forming a ubiquitin chain.
Synonyms:exact_synonym: protein polyubiquitinylation;   protein polyubiquitylation
 related_synonym: polyubiquitin


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protein polyubiquitination term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AMFR autocrine motility factor receptor ISO (PMID:17310145), (PMID:19103148)
(PMID:24810856)
UniProtKB
ParkinsonsUK-UCL
PMID:17310145, PMID:19103148, PMID:24810856 NCBI chr16:36,647,792...36,711,782
Ensembl chr16:55,780,633...55,843,744
JBrowse link
G ARIH2 ariadne RBR E3 ubiquitin protein ligase 2 ISO (PMID:16118314), (PMID:19340006) UniProtKB PMID:16118314, PMID:19340006 NCBI chr 3:48,844,161...48,910,183
Ensembl chr 3:49,926,453...49,991,924
JBrowse link
G ASB2 ankyrin repeat and SOCS box containing 2 ISO (MGI:4830849|PMID:19300455) MGI PMID:19300455 MGI:4830849 NCBI chr14:74,566,607...74,608,905
Ensembl chr14:93,900,914...93,930,527
JBrowse link
G AXIN1 axin 1 ISO (MGI:3628833|PMID:16601693) MGI PMID:16601693 MGI:3628833 Ensembl chr16:278,239...337,891 JBrowse link
G BCL2 BCL2 apoptosis regulator ISO (PMID:16717086) MGI PMID:16717086 NCBI chr18:56,481,212...56,679,012
Ensembl chr18:59,802,443...59,992,100
JBrowse link
G BFAR bifunctional apoptosis regulator ISO (PMID:21068390) ParkinsonsUK-UCL PMID:21068390 NCBI chr16:13,558,912...13,597,023
Ensembl chr16:14,980,615...15,018,310
JBrowse link
G BIRC2 baculoviral IAP repeat containing 2 ISO (PMID:11907583) UniProtKB PMID:11907583 NCBI chr11:97,298,736...97,324,966
Ensembl chr11:100,793,036...100,822,421
JBrowse link
G BTRC beta-transducin repeat containing E3 ubiquitin protein ligase ISO (PMID:12820959)
(MGI:1336762|PMID:10228155)
ParkinsonsUK-UCL
BHF-UCL
PMID:10228155, PMID:12820959 MGI:1336762 NCBI chr10:97,958,527...98,159,550
Ensembl chr10:101,431,318...101,632,496
JBrowse link
G C10H10orf90 chromosome 10 C10orf90 homolog ISO (MGI:6201913|PMID:24240685) UniProt PMID:24240685 MGI:6201913 NCBI chr10:122,987,122...123,243,653
Ensembl chr10:127,259,451...127,357,119
JBrowse link
G CBFB core-binding factor subunit beta ISO (PMID:22190036) CACAO PMID:22190036 NCBI chr16:47,373,543...47,446,783 JBrowse link
G CBL Cbl proto-oncogene ISO RGD PMID:17675467 RGD:11576315 NCBI chr11:114,044,996...114,149,204
Ensembl chr11:117,973,187...118,074,671
JBrowse link
G CDC34 cell division cycle 34, ubiqiutin conjugating enzyme ISO (PMID:20347421) UniProtKB PMID:20347421 NCBI chr19:592,856...602,811
Ensembl chr19:502,766...512,173
JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A ISO (PMID:18305112) UniProtKB PMID:18305112 NCBI chr 9:21,803,862...21,831,322 JBrowse link
G CTNNB1 catenin beta 1 ISO (PMID:29374064) UniProt PMID:29374064 NCBI chr 3:41,104,940...41,145,934
Ensembl chr 3:41,373,726...41,414,030
JBrowse link
G CUL3 cullin 3 ISO (PMID:14528312), (PMID:19261606)
(MGI:5806303|PMID:27708159)
UniProt
MGI
PMID:14528312, PMID:19261606, PMID:27708159 MGI:5806303 NCBI chr2B:111,714,533...111,827,080
Ensembl chr2B:230,289,195...230,378,991
JBrowse link
G DCAF15 DDB1 and CUL4 associated factor 15 ISO (PMID:28302793), (PMID:28437394), (PMID:31452512), (PMID:31686031) UniProt PMID:28302793, PMID:28437394, PMID:31452512, PMID:31686031 NCBI chr19:13,514,672...13,523,689
Ensembl chr19:14,243,793...14,252,804
JBrowse link
G DDA1 DET1 and DDB1 associated 1 ISO (PMID:31686031) UniProt PMID:31686031 NCBI chr19:16,797,750...16,808,427
Ensembl chr19:17,771,925...17,785,267
JBrowse link
G DDB2 damage specific DNA binding protein 2 ISO (PMID:12732143) UniProtKB PMID:12732143 NCBI chr11:47,161,345...47,185,526
Ensembl chr11:47,714,723...47,738,761
JBrowse link
G DTL denticleless E3 ubiquitin protein ligase homolog ISO (PMID:18794347) UniProtKB PMID:18794347 NCBI chr 1:187,603,600...187,672,006
Ensembl chr 1:192,466,408...192,535,071
JBrowse link
G DZIP3 DAZ interacting zinc finger protein 3 ISO (PMID:12538761) UniProtKB PMID:12538761 NCBI chr 3:105,714,315...105,819,594
Ensembl chr 3:112,646,133...112,751,299
JBrowse link
G ERCC8 ERCC excision repair 8, CSA ubiquitin ligase complex subunit ISO (PMID:12732143) UniProtKB PMID:12732143 NCBI chr 5:53,053,712...53,131,563
Ensembl chr 5:54,693,987...54,765,496
JBrowse link
G FBXL17 F-box and leucine rich repeat protein 17 ISO (PMID:27234298) UniProt PMID:27234298 NCBI chr 5:103,214,110...103,739,494 JBrowse link
G FBXL7 F-box and leucine rich repeat protein 7 ISO (PMID:25778398)
(MGI:6368091|PMID:25778398)
(PMID:28218735)
UniProt PMID:25778398, PMID:28218735 MGI:6368091 NCBI chr 5:15,804,479...16,237,326
Ensembl chr 5:15,643,846...16,075,623
JBrowse link
G FBXO22 F-box protein 22 ISO (MGI:3840749|PMID:19319192) MGI PMID:19319192 MGI:3840749 NCBI chr15:54,817,076...54,849,271
Ensembl chr15:74,410,213...74,441,609
JBrowse link
G FBXO4 F-box protein 4 ISO (PMID:16275645), (PMID:20181953) UniProtKB PMID:16275645, PMID:20181953 NCBI chr 5:68,336,673...68,474,481
Ensembl chr 5:73,500,850...73,517,051
JBrowse link
G FBXW11 F-box and WD repeat domain containing 11 ISO (PMID:20347421)
(MGI:2176150|PMID:11896578)
UniProtKB
UniProt
PMID:11896578, PMID:20347421 MGI:2176150 NCBI chr 5:167,207,643...167,354,730
Ensembl chr 5:174,124,499...174,271,977
JBrowse link
G G2E3 G2/M-phase specific E3 ubiquitin protein ligase ISO (MGI:3807157|PMID:18511420) MGI PMID:18511420 MGI:3807157 NCBI chr14:11,338,212...11,398,545
Ensembl chr14:29,484,584...29,539,430
JBrowse link
G HDAC6 histone deacetylase 6 ISO (MGI:2153694|PMID:11689694) MGI PMID:11689694 MGI:2153694 NCBI chr  X:41,099,539...41,122,650
Ensembl chr  X:48,960,430...48,982,642
JBrowse link
G HUWE1 HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1 ISO (PMID:15989957) UniProtKB PMID:15989957 NCBI chr  X:45,746,228...45,897,250
Ensembl chr  X:53,855,404...54,005,366
JBrowse link
G IRF2BP1 interferon regulatory factor 2 binding protein 1 ISO (PMID:18671972) ARUK-UCL PMID:18671972 NCBI chr19:42,893,381...42,896,189 JBrowse link
G ITCH itchy E3 ubiquitin protein ligase ISO (MGI:3038342|PMID:14973438) MGI PMID:14973438 MGI:3038342 NCBI chr20:30,690,172...30,840,504
Ensembl chr20:31,852,203...31,971,945
JBrowse link
G JADE2 jade family PHD finger 2 ISO (MGI:5605922|PMID:25018020) MGI PMID:25018020 MGI:5605922 NCBI chr 5:129,929,127...129,986,367
Ensembl chr 5:136,087,999...136,129,929
JBrowse link
G KLHL42 kelch like family member 42 ISO (PMID:19261606) UniProtKB PMID:19261606 NCBI chr12:58,509,031...58,531,891
Ensembl chr12:61,127,167...61,149,126
JBrowse link
G LOC100974874 E3 ubiquitin-protein ligase CHFR ISO (PMID:19182791)
(MGI:3575445|PMID:15793587)
UniProtKB
MGI
PMID:15793587, PMID:19182791 MGI:3575445 NCBI chr12:130,201,704...130,247,891
Ensembl chr12:134,923,458...134,968,832
JBrowse link
G LRSAM1 leucine rich repeat and sterile alpha motif containing 1 ISO (PMID:18077552) UniProtKB PMID:18077552 NCBI chr 9:98,571,796...98,623,581
Ensembl chr 9:127,245,508...127,297,645
JBrowse link
G MAP3K1 mitogen-activated protein kinase kinase kinase 1 ISO RGD PMID:12049732 RGD:729224 NCBI chr 5:57,116,405...57,197,017
Ensembl chr 5:58,745,579...58,826,959
JBrowse link
G MARCHF1 membrane associated ring-CH-type finger 1 ISO (PMID:27577745)
(MGI:3703462|PMID:17255932)
(PMID:19117940)
CACAO
UniProt
UniProtKB
PMID:17255932, PMID:19117940, PMID:27577745 MGI:3703462 NCBI chr 4:155,791,599...156,639,456 JBrowse link
G MARCHF5 membrane associated ring-CH-type finger 5 ISO (PMID:16936636) UniProtKB PMID:16936636 NCBI chr10:89,038,753...89,101,305
Ensembl chr10:92,556,500...92,618,319
JBrowse link
G MARCHF8 membrane associated ring-CH-type finger 8 ISO (PMID:19117940) UniProtKB PMID:19117940 NCBI chr10:42,539,079...42,677,277
Ensembl chr10:45,718,172...45,796,771
JBrowse link
G MGRN1 mahogunin ring finger 1 ISO (MGI:2449384|PMID:12560552) MGI PMID:12560552 MGI:2449384 NCBI chr16:3,550,352...3,615,693
Ensembl chr16:4,740,763...4,782,638
JBrowse link
G MKRN1 makorin ring finger protein 1 ISO (PMID:19536131) FlyBase PMID:19536131 NCBI chr 7:132,391,357...132,417,395
Ensembl chr 7:144,867,541...144,893,658
JBrowse link
G MUL1 mitochondrial E3 ubiquitin protein ligase 1 ISO (PMID:21597459) UniProt PMID:21597459 NCBI chr 1:19,454,792...19,463,527
Ensembl chr 1:20,496,356...20,505,281
JBrowse link
G NFE2L1 nuclear factor, erythroid 2 like 1 ISO (MGI:5433806|PMID:21554501) MGI PMID:21554501 MGI:5433806 NCBI chr17:9,476,482...9,489,661
Ensembl chr17:9,657,847...9,671,040
JBrowse link
G NHLRC1 NHL repeat containing E3 ubiquitin protein ligase 1 ISO (PMID:15930137) UniProtKB PMID:15930137 NCBI chr 6:17,969,146...17,970,962
Ensembl chr 6:18,321,728...18,322,915
JBrowse link
G PELI1 pellino E3 ubiquitin protein ligase 1 ISO (MGI:5291872|PMID:21874024) MGI PMID:21874024 MGI:5291872 NCBI chr2A:64,160,362...64,213,200
Ensembl chr2A:65,284,480...65,336,339
JBrowse link
G PPIL2 peptidylprolyl isomerase like 2 ISO (PMID:11435423) MGI PMID:11435423 NCBI chr22:3,788,603...3,821,090
Ensembl chr22:20,272,383...20,304,130
JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase ISO (PMID:12150907), (PMID:16227987), (PMID:18541373), (PMID:19880420)
(PMID:32047033)
ParkinsonsUK-UCL
UniProt
PMID:12150907, PMID:16227987, PMID:18541373, PMID:19880420, PMID:32047033 NCBI chr 6:159,293,016...160,679,106
Ensembl chr 6:164,314,990...165,678,770
JBrowse link
G PRPF19 pre-mRNA processing factor 19 ISO (PMID:11435423) MGI PMID:11435423 NCBI chr11:56,153,965...56,169,821
Ensembl chr11:59,595,120...59,607,828
JBrowse link
G RBCK1 RANBP2-type and C3HC4-type zinc finger containing 1 ISO (PMID:12629548), (PMID:17006537) UniProtKB PMID:12629548, PMID:17006537 NCBI chr20:615,987...639,366
Ensembl chr20:386,569...409,580
JBrowse link
G RBX1 ring-box 1 ISO (PMID:14528312) UniProt PMID:14528312 NCBI chr22:21,845,351...21,866,627
Ensembl chr22:39,941,405...39,962,175
JBrowse link
G RC3H1 ring finger and CCCH-type domains 1 ISO (PMID:26489670) UniProtKB PMID:26489670 NCBI chr 1:149,454,748...149,539,566
Ensembl chr 1:153,160,661...153,213,402
JBrowse link
G RC3H2 ring finger and CCCH-type domains 2 ISO (PMID:26489670)
(PMID:24448648)
UniProtKB
FlyBase
PMID:24448648, PMID:26489670 NCBI chr 9:93,975,164...94,031,516
Ensembl chr 9:122,313,791...122,365,102
JBrowse link
G RNF111 ring finger protein 111 ISO (MGI:3628833|PMID:16601693) MGI PMID:16601693 MGI:3628833 NCBI chr15:37,957,390...38,068,006
Ensembl chr15:56,265,379...56,374,484
JBrowse link
G RNF125 ring finger protein 125 ISO (PMID:27411375) UniProtKB PMID:27411375 NCBI chr18:25,227,353...25,297,186
Ensembl chr18:28,824,183...28,873,068
JBrowse link
G RNF135 ring finger protein 135 ISO (PMID:31006531)
(MGI:6152590|PMID:21147464)
UniProt PMID:21147464, PMID:31006531 MGI:6152590 NCBI chr17:25,843,447...25,869,874 JBrowse link
G RNF165 ring finger protein 165 ISO (MGI:5499270|PMID:23610558) MGI PMID:23610558 MGI:5499270 NCBI chr18:39,615,759...39,742,492
Ensembl chr18:43,244,066...43,274,212
JBrowse link
G RNF167 ring finger protein 167 ISO (PMID:16314844) UniProtKB PMID:16314844 NCBI chr17:4,988,275...4,993,423
Ensembl chr17:4,975,849...4,981,335
JBrowse link
G RNF180 ring finger protein 180 ISO (MGI:5505713|PMID:23926250) MGI PMID:23926250 MGI:5505713 NCBI chr 5:49,624,452...49,841,741
Ensembl chr 5:51,280,064...51,454,750
JBrowse link
G RNF183 ring finger protein 183 ISO (PMID:26567849)
(PMID:29507230)
UniProtKB
UniProt
PMID:26567849, PMID:29507230 NCBI chr 9:84,396,738...84,404,057 JBrowse link
G RNF20 ring finger protein 20 ISO (PMID:19037095) UniProtKB PMID:19037095 NCBI chr 9:72,738,132...72,767,868
Ensembl chr 9:100,732,342...100,761,258
JBrowse link
G RNF31 ring finger protein 31 ISO (PMID:12629548), (PMID:17006537) UniProtKB PMID:12629548, PMID:17006537 NCBI chr14:4,923,391...4,936,959 JBrowse link
G RNF41 ring finger protein 41 ISO (PMID:14765125), (PMID:18541373)
(MGI:3819273|PMID:18495327)
UniProtKB
MGI
PMID:14765125, PMID:18495327, PMID:18541373 MGI:3819273 NCBI chr12:32,693,349...32,710,866
Ensembl chr12:32,944,814...32,962,584
JBrowse link
G RUSC1 RUN and SH3 domain containing 1 ISO (PMID:19365808) UniProtKB PMID:19365808 NCBI chr 1:130,665,390...130,675,635
Ensembl chr 1:134,270,420...134,280,592
JBrowse link
G SASH1 SAM and SH3 domain containing 1 ISO (PMID:23776175) MGI PMID:23776175 NCBI chr 6:146,154,178...146,368,101
Ensembl chr 6:150,863,677...151,075,816
JBrowse link
G SHPRH SNF2 histone linker PHD RING helicase ISO (PMID:17108083) FlyBase PMID:17108083 NCBI chr 6:143,628,076...143,751,370
Ensembl chr 6:148,388,329...148,457,023
JBrowse link
G SKP1 S-phase kinase associated protein 1 ISO (PMID:12820959) ParkinsonsUK-UCL PMID:12820959 NCBI chr 5:129,560,086...129,580,188
Ensembl chr 5:135,713,085...135,729,653
JBrowse link
G SKP2 S-phase kinase associated protein 2 ISO (MGI:3768604|PMID:17785450) MGI PMID:17785450 MGI:3768604 NCBI chr 5:74,179,608...74,211,563
Ensembl chr 5:79,461,018...79,492,311
JBrowse link
G SMURF1 SMAD specific E3 ubiquitin protein ligase 1 ISO (PMID:19937093) UniProtKB PMID:19937093 NCBI chr 7:90,995,923...91,112,240
Ensembl chr 7:104,500,965...104,568,046
JBrowse link
G SPOP speckle type BTB/POZ protein ISO (PMID:14528312) UniProt PMID:14528312 NCBI chr17:43,685,913...43,765,277
Ensembl chr17:48,417,634...48,440,623
JBrowse link
G STUB1 STIP1 homology and U-box containing protein 1 ISO (PMID:15781469), (PMID:16275660)
(MGI:2149486|PMID:11435423)
(PMID:19713937)
HGNC
MGI
UniProtKB
PMID:11435423, PMID:15781469, PMID:16275660, PMID:19713937 MGI:2149486 Ensembl chr16:694,414...696,682 JBrowse link
G TAF1 TATA-box binding protein associated factor 1 ISO (PMID:20181722) ParkinsonsUK-UCL PMID:20181722 NCBI chr  X:60,630,137...60,729,904
Ensembl chr  X:70,684,217...70,782,323
JBrowse link
G TMEM129 transmembrane protein 129, E3 ubiquitin ligase ISO (PMID:24807418) ParkinsonsUK-UCL PMID:24807418 NCBI chr 4:1,853,126...1,858,461
Ensembl chr 4:1,767,517...1,772,643
JBrowse link
G TNKS tankyrase ISO (PMID:19759537), (PMID:21478859) UniProtKB PMID:19759537, PMID:21478859 NCBI chr 8:9,435,412...9,654,810 JBrowse link
G TNKS2 tankyrase 2 ISO (PMID:19759537), (PMID:21478859) UniProtKB PMID:19759537, PMID:21478859 NCBI chr10:88,547,396...88,612,973
Ensembl chr10:92,070,362...92,134,911
JBrowse link
G TOPORS TOP1 binding arginine/serine rich protein, E3 ubiquitin ligase ISO (PMID:15247280) BHF-UCL PMID:15247280 NCBI chr 9:32,314,850...32,327,067
Ensembl chr 9:33,124,730...33,135,129
JBrowse link
G TRAF6 TNF receptor associated factor 6 ISO (PMID:15125833), (PMID:19675569) UniProtKB PMID:15125833, PMID:19675569 NCBI chr11:36,457,633...36,483,616
Ensembl chr11:36,335,609...36,356,334
JBrowse link
G TRIM21 tripartite motif containing 21 ISO (PMID:16297862) UniProtKB PMID:16297862 NCBI chr11:4,588,083...4,596,942
Ensembl chr11:4,254,152...4,262,981
JBrowse link
G TRIM32 tripartite motif containing 32 ISO (PMID:18632609)
(MGI:5320515|PMID:22299041)
BHF-UCL
MGI
PMID:18632609, PMID:22299041 MGI:5320515 NCBI chr 9:87,819,723...87,838,684
Ensembl chr 9:116,183,746...116,185,707
JBrowse link
G TRIM6 tripartite motif containing 6 ISO (MGI:5492022|PMID:22328504) UniProt PMID:22328504 MGI:5492022 NCBI chr11:5,731,256...5,748,057 JBrowse link
G TRIP12 thyroid hormone receptor interactor 12 ISO (PMID:30982744) UniProt PMID:30982744 NCBI chr2B:117,013,343...117,175,296
Ensembl chr2B:235,820,182...235,979,780
JBrowse link
G UBE2B ubiquitin conjugating enzyme E2 B ISO (PMID:18339854) UniProtKB PMID:18339854 NCBI chr 5:129,775,011...129,794,853
Ensembl chr 5:135,925,217...135,944,609
JBrowse link
G UBE2D1 ubiquitin conjugating enzyme E2 D1 ISO (PMID:15247280), (PMID:16275645)
(MGI:3807157|PMID:18511420)
UniProtKB
MGI
PMID:15247280, PMID:16275645, PMID:18511420 MGI:3807157 NCBI chr10:54,867,346...54,903,125
Ensembl chr10:57,087,811...57,123,581
JBrowse link
G UBE2D2 ubiquitin conjugating enzyme E2 D2 ISO (PMID:15247280) BHF-UCL PMID:15247280 NCBI chr 5:134,927,150...134,995,298
Ensembl chr 5:141,048,385...141,115,842
JBrowse link
G UBE2D3 ubiquitin conjugating enzyme E2 D3 ISO (PMID:14765125), (PMID:16522193) UniProtKB PMID:14765125, PMID:16522193 NCBI chr 4:95,218,319...95,293,053 JBrowse link
G UBE2E1 ubiquitin conjugating enzyme E2 E1 ISO (PMID:15247280), (PMID:16522193) BHF-UCL PMID:15247280, PMID:16522193 NCBI chr 3:23,719,632...23,803,302
Ensembl chr 3:24,045,747...24,127,820
JBrowse link
G UBE2L3 ubiquitin conjugating enzyme E2 L3 ISO (PMID:10888878), (PMID:14765125) UniProtKB PMID:10888878, PMID:14765125 NCBI chr22:3,690,100...3,746,665 JBrowse link
G UBE3C ubiquitin protein ligase E3C ISO (PMID:11278995) UniProtKB PMID:11278995 NCBI chr 7:148,756,024...148,886,688
Ensembl chr 7:160,474,767...160,580,046
JBrowse link
G UBE3D ubiquitin protein ligase E3D ISO (PMID:15749827) UniProtKB PMID:15749827 NCBI chr 6:80,729,751...80,962,322
Ensembl chr 6:84,062,079...84,236,860
JBrowse link
G UBE4A ubiquitination factor E4A ISO (MGI:2149486|PMID:11435423) MGI PMID:11435423 MGI:2149486 NCBI chr11:113,193,986...113,233,660
Ensembl chr11:117,131,100...117,162,385
JBrowse link
G UBE4B ubiquitination factor E4B ISO (MGI:3610695|PMID:16314518)
(MGI:2149486|PMID:11435423), (MGI:5471850|PMID:23509263)
MGI PMID:11435423, PMID:16314518, PMID:23509263 MGI:2149486, MGI:3610695, MGI:5471850 NCBI chr 1:8,801,707...8,949,465
Ensembl chr 1:10,033,084...10,178,759
JBrowse link
G UBOX5 U-box domain containing 5 ISO (MGI:2149486|PMID:11435423) MGI PMID:11435423 MGI:2149486 NCBI chr20:3,196,189...3,246,238
Ensembl chr20:2,958,062...3,008,905
JBrowse link
G UBR5 ubiquitin protein ligase E3 component n-recognin 5 ISO (PMID:21118991), (PMID:28689657) BHF-UCL PMID:21118991, PMID:28689657 NCBI chr 8:98,904,557...99,064,121
Ensembl chr 8:101,067,435...101,224,913
JBrowse link
G ZSWIM2 zinc finger SWIM-type containing 2 ISO (MGI:3692348|PMID:16522193) UniProt PMID:16522193 MGI:3692348 NCBI chr2B:74,120,669...74,142,560 JBrowse link
histone H2A K63-linked ubiquitination term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RNF168 ring finger protein 168 ISO (PMID:19203578), (PMID:19203579), (PMID:19500350)
(PMID:20550933)
UniProtKB PMID:19203578, PMID:19203579, PMID:19500350, PMID:20550933 NCBI chr 3:193,814,785...193,848,620
Ensembl chr 3:203,756,589...203,790,687
JBrowse link
G RNF8 ring finger protein 8 ISO (PMID:22980979)
(PMID:20550933)
UniProtKB PMID:20550933, PMID:22980979 NCBI chr 6:36,918,705...36,955,380
Ensembl chr 6:38,108,414...38,145,949
JBrowse link
negative regulation of histone H2A K63-linked ubiquitination term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G OTUB1 OTU deubiquitinase, ubiquitin aldehyde binding 1 ISO (PMID:20725033) UniProtKB PMID:20725033 NCBI chr11:59,342,820...59,355,386
Ensembl chr11:62,690,542...62,706,542
JBrowse link
G TRIP12 thyroid hormone receptor interactor 12 ISO (PMID:22884692) UniProtKB PMID:22884692 NCBI chr2B:117,013,343...117,175,296
Ensembl chr2B:235,820,182...235,979,780
JBrowse link
G UBR5 ubiquitin protein ligase E3 component n-recognin 5 ISO (PMID:22884692) UniProtKB PMID:22884692 NCBI chr 8:98,904,557...99,064,121
Ensembl chr 8:101,067,435...101,224,913
JBrowse link
negative regulation of protein K48-linked ubiquitination term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PPIA peptidylprolyl isomerase A ISO (PMID:30328013) UniProt PMID:30328013 NCBI chr 7:45,510,450...45,515,448
Ensembl chr 7:45,578,765...45,605,545
JBrowse link
G TRIM44 tripartite motif containing 44 ISO (PMID:23460740) BHF-UCL PMID:23460740 NCBI chr11:35,633,985...35,782,260
Ensembl chr11:35,508,083...35,656,684
JBrowse link
negative regulation of protein K63-linked ubiquitination term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GPS2 G protein pathway suppressor 2 ISO (MGI:5896692|PMID:28039360)
(MGI:6148392|PMID:24953653), (MGI:6148396|PMID:29499132), (MGI:6148454|PMID:22424771)
UniProt PMID:22424771, PMID:24953653, PMID:28039360, PMID:29499132 MGI:5896692, MGI:6148392, MGI:6148396, MGI:6148454 NCBI chr17:7,346,766...7,349,682
Ensembl chr17:7,333,571...7,335,871
JBrowse link
G PARP10 poly(ADP-ribose) polymerase family member 10 ISO (PMID:23575687) UniProtKB PMID:23575687 NCBI chr 8:140,743,061...140,744,014
Ensembl chr 8:143,735,819...143,744,138
JBrowse link
G PLAA phospholipase A2 activating protein ISO (MGI:5883825|PMID:28413018) UniProt PMID:28413018 MGI:5883825 NCBI chr 9:26,749,607...26,793,580
Ensembl chr 9:27,357,437...27,401,103
JBrowse link
negative regulation of protein polyubiquitination term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DYSF dysferlin ISO (MGI:5433472|PMID:20724702) MGI PMID:20724702 MGI:5433472 NCBI chr2A:71,495,573...71,730,073
Ensembl chr2A:72,994,888...73,228,846
JBrowse link
G TTC36 tetratricopeptide repeat domain 36 ISO (MGI:6362140|PMID:31537781) MGI PMID:31537781 MGI:6362140 NCBI chr11:113,364,559...113,368,586
Ensembl chr11:117,295,191...117,298,928
JBrowse link
positive regulation of protein K48-linked ubiquitination term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BIRC2 baculoviral IAP repeat containing 2 ISO (PMID:21931591) UniProtKB PMID:21931591 NCBI chr11:97,298,736...97,324,966
Ensembl chr11:100,793,036...100,822,421
JBrowse link
G NMI N-myc and STAT interactor ISO (MGI:5546557|PMID:23956435) MGI PMID:23956435 MGI:5546557 NCBI chr2B:8,574,385...8,603,486
Ensembl chr2B:155,802,720...155,823,142
JBrowse link
positive regulation of protein K63-linked ubiquitination term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BIRC2 baculoviral IAP repeat containing 2 ISO (PMID:21931591) UniProtKB PMID:21931591 NCBI chr11:97,298,736...97,324,966
Ensembl chr11:100,793,036...100,822,421
JBrowse link
G DDX3X DEAD-box helicase 3 X-linked ISO (PMID:27980081) UniProt PMID:27980081 NCBI chr  X:33,780,381...33,796,829
Ensembl chr  X:41,475,116...41,505,837
JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 ISO (PMID:25891078) UniProtKB PMID:25891078 NCBI chr16:30,955,976...30,995,451
Ensembl chr16:49,837,891...49,873,773
JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 ISO (PMID:23871208)
(MGI:5562517|PMID:23871208)
UniProtKB
UniProt
PMID:23871208 MGI:5562517 NCBI chr 1:88,685,736...88,743,164
Ensembl chr 1:123,734,511...123,790,830
JBrowse link
positive regulation of protein linear polyubiquitination term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PRKN parkin RBR E3 ubiquitin protein ligase ISO (PMID:23453807)
(MGI:5495588|PMID:23453807)
ParkinsonsUK-UCL PMID:23453807 MGI:5495588 NCBI chr 6:159,293,016...160,679,106
Ensembl chr 6:164,314,990...165,678,770
JBrowse link
G XIAP X-linked inhibitor of apoptosis ISO (PMID:21931591) UniProtKB PMID:21931591 NCBI chr  X:113,052,164...113,105,160
Ensembl chr  X:123,232,643...123,278,606
JBrowse link
positive regulation of protein polyubiquitination term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BIRC2 baculoviral IAP repeat containing 2 ISO (MGI:3819901|PMID:18621737) MGI PMID:18621737 MGI:3819901 NCBI chr11:97,298,736...97,324,966
Ensembl chr11:100,793,036...100,822,421
JBrowse link
G BIRC3 baculoviral IAP repeat containing 3 ISO (MGI:3819901|PMID:18621737) MGI PMID:18621737 MGI:3819901 NCBI chr11:97,269,778...97,290,112
Ensembl chr11:100,763,274...100,785,194
JBrowse link
G FBXO4 F-box protein 4 ISO (MGI:5299398|PMID:21911473) MGI PMID:21911473 MGI:5299398 NCBI chr 5:68,336,673...68,474,481
Ensembl chr 5:73,500,850...73,517,051
JBrowse link
G HAMP hepcidin antimicrobial peptide ISO (PMID:22682227) BHF-UCL PMID:22682227 NCBI chr19:32,228,701...32,231,494
Ensembl chr19:40,964,445...40,968,861
JBrowse link
G MARCHF7 membrane associated ring-CH-type finger 7 ISO (PMID:29295817) UniProtKB PMID:29295817 NCBI chr2B:47,004,211...47,059,901
Ensembl chr2B:164,377,605...164,432,907
JBrowse link
G RNF40 ring finger protein 40 ISO RGD PMID:12121982 RGD:633892 NCBI chr16:24,194,293...24,207,460
Ensembl chr16:31,129,352...31,142,280
JBrowse link
G SKP2 S-phase kinase associated protein 2 ISO (MGI:5468878|PMID:23277542) MGI PMID:23277542 MGI:5468878 NCBI chr 5:74,179,608...74,211,563
Ensembl chr 5:79,461,018...79,492,311
JBrowse link
G SPSB4 splA/ryanodine receptor domain and SOCS box containing 4 ISO (PMID:28931592) UniProt PMID:28931592 NCBI chr 3:138,085,136...138,181,747
Ensembl chr 3:145,682,533...145,779,049
JBrowse link
G UBE2D1 ubiquitin conjugating enzyme E2 D1 ISO (MGI:3819901|PMID:18621737) MGI PMID:18621737 MGI:3819901 NCBI chr10:54,867,346...54,903,125
Ensembl chr10:57,087,811...57,123,581
JBrowse link
protein K11-linked ubiquitination term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANAPC1 anaphase promoting complex subunit 1 ISO (PMID:18485873) UniProtKB PMID:18485873 NCBI chr2A:90,143,737...90,262,215 JBrowse link
G ANAPC10 anaphase promoting complex subunit 10 ISO (PMID:18485873) UniProtKB PMID:18485873 NCBI chr 4:137,339,959...137,445,172
Ensembl chr 4:149,001,637...149,105,836
JBrowse link
G ANAPC11 anaphase promoting complex subunit 11 ISO (PMID:18485873) UniProtKB PMID:18485873 NCBI chr17:76,297,262...76,305,826
Ensembl chr17:82,002,135...82,007,921
JBrowse link
G ANAPC13 anaphase promoting complex subunit 13 ISO (PMID:18485873) UniProtKB PMID:18485873 NCBI chr 3:131,524,227...131,532,624
Ensembl chr 3:138,995,860...139,004,179
JBrowse link
G ANAPC2 anaphase promoting complex subunit 2 ISO (PMID:18485873) UniProtKB PMID:18485873 NCBI chr 9:108,234,949...108,248,227
Ensembl chr 9:137,204,356...137,217,652
JBrowse link
G ANAPC4 anaphase promoting complex subunit 4 ISO (PMID:18485873) UniProtKB PMID:18485873 NCBI chr 4:19,777,750...19,817,459
Ensembl chr 4:25,061,930...25,101,260
JBrowse link
G ANAPC5 anaphase promoting complex subunit 5 ISO (PMID:18485873) UniProtKB PMID:18485873 NCBI chr12:118,906,482...118,950,913
Ensembl chr12:122,279,227...122,324,428
JBrowse link
G ANAPC7 anaphase promoting complex subunit 7 ISO (PMID:18485873) UniProtKB PMID:18485873 NCBI chr12:107,946,756...107,977,489
Ensembl chr12:111,338,045...111,368,466
JBrowse link
G CDC16 cell division cycle 16 ISO (PMID:18485873) UniProtKB PMID:18485873 NCBI chr13:95,300,763...95,340,762
Ensembl chr13:114,369,774...114,407,267
JBrowse link
G CDC23 cell division cycle 23 ISO (PMID:18485873) UniProtKB PMID:18485873 NCBI chr 5:133,566,022...133,591,528
Ensembl chr 5:139,699,421...139,724,991
JBrowse link
G CDC26 cell division cycle 26 ISO (PMID:18485873) UniProtKB PMID:18485873 NCBI chr 9:84,364,810...84,373,406
Ensembl chr 9:112,736,864...112,745,466
JBrowse link
G CDC27 cell division cycle 27 ISO (PMID:18485873) UniProtKB PMID:18485873 NCBI chr17:10,259,194...10,331,011
Ensembl chr17:10,473,646...10,545,549
JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase ISO (PMID:25621951) UniProtKB PMID:25621951 NCBI chr 6:159,293,016...160,679,106
Ensembl chr 6:164,314,990...165,678,770
JBrowse link
G RNF26 ring finger protein 26 ISO (PMID:25254379) UniProtKB PMID:25254379 NCBI chr11:114,175,586...114,178,379
Ensembl chr11:118,103,505...118,104,806
JBrowse link
G RNF4 ring finger protein 4 ISO PMID:18408734 UniProt PMID:18408734 RGD:8553731 NCBI chr 4:2,614,918...2,661,785
Ensembl chr 4:2,540,612...2,563,937
JBrowse link
G UBE2A ubiquitin conjugating enzyme E2 A ISO (PMID:20061386) UniProtKB PMID:20061386 NCBI chr  X:108,606,271...108,617,000
Ensembl chr  X:119,034,235...119,049,655
JBrowse link
G UBE2B ubiquitin conjugating enzyme E2 B ISO (PMID:20061386) UniProtKB PMID:20061386 NCBI chr 5:129,775,011...129,794,853
Ensembl chr 5:135,925,217...135,944,609
JBrowse link
G UBE2C ubiquitin conjugating enzyme E2 C ISO (PMID:18485873), (PMID:19822757), (PMID:20061386) UniProtKB PMID:18485873, PMID:19822757, PMID:20061386 NCBI chr20:42,152,219...42,156,246
Ensembl chr20:43,239,382...43,243,464
JBrowse link
G UBE2D3 ubiquitin conjugating enzyme E2 D3 ISO (PMID:20061386) UniProtKB PMID:20061386 NCBI chr 4:95,218,319...95,293,053 JBrowse link
G UBE2D4 ubiquitin conjugating enzyme E2 D4 (putative) ISO (PMID:20061386) UniProtKB PMID:20061386 NCBI chr 7:40,295,047...40,324,705 JBrowse link
G UBE2E2 ubiquitin conjugating enzyme E2 E2 ISO (PMID:20061386) UniProtKB PMID:20061386 NCBI chr 3:23,121,699...23,502,329
Ensembl chr 3:23,446,158...23,825,277
JBrowse link
G UBE2E3 ubiquitin conjugating enzyme E2 E3 ISO (PMID:20061386) UniProtKB PMID:20061386 NCBI chr2B:68,245,028...68,328,059
Ensembl chr2B:186,057,033...186,139,384
JBrowse link
G UBE2H ubiquitin conjugating enzyme E2 H ISO (PMID:20061386) UniProtKB PMID:20061386 NCBI chr 7:121,796,629...121,917,981
Ensembl chr 7:134,318,166...134,437,295
JBrowse link
G UBE2L3 ubiquitin conjugating enzyme E2 L3 ISO (PMID:20061386) UniProtKB PMID:20061386 NCBI chr22:3,690,100...3,746,665 JBrowse link
G UBE2S ubiquitin conjugating enzyme E2 S ISO (PMID:19822757), (PMID:20061386), (PMID:20622874), (PMID:21376237) UniProtKB PMID:19822757, PMID:20061386, PMID:20622874, PMID:21376237 NCBI chr19:52,444,270...52,450,770
Ensembl chr19:61,133,934...61,140,786
JBrowse link
G UBE2T ubiquitin conjugating enzyme E2 T ISO (PMID:20061386) UniProtKB PMID:20061386 NCBI chr 1:177,929,298...177,939,027
Ensembl chr 1:182,227,166...182,236,712
JBrowse link
G UBE2W ubiquitin conjugating enzyme E2 W ISO (PMID:20061386) UniProtKB PMID:20061386 NCBI chr 8:70,315,767...70,413,148 JBrowse link
protein K27-linked ubiquitination term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RNF6 ring finger protein 6 ISO (PMID:19345326) UniProtKB PMID:19345326 NCBI chr13:7,505,669...7,515,542
Ensembl chr13:25,854,765...25,864,629
JBrowse link
G UBE2D4 ubiquitin conjugating enzyme E2 D4 (putative) ISO (PMID:20061386) UniProtKB PMID:20061386 NCBI chr 7:40,295,047...40,324,705 JBrowse link
G UBE2S ubiquitin conjugating enzyme E2 S ISO (PMID:20061386) UniProtKB PMID:20061386 NCBI chr19:52,444,270...52,450,770
Ensembl chr19:61,133,934...61,140,786
JBrowse link
G UBE2T ubiquitin conjugating enzyme E2 T ISO (PMID:20061386) UniProtKB PMID:20061386 NCBI chr 1:177,929,298...177,939,027
Ensembl chr 1:182,227,166...182,236,712
JBrowse link
protein K29-linked ubiquitination term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ITCH itchy E3 ubiquitin protein ligase ISO (PMID:17028573), (PMID:18628966) UniProtKB PMID:17028573, PMID:18628966 NCBI chr20:30,690,172...30,840,504
Ensembl chr20:31,852,203...31,971,945
JBrowse link
G RNF186 ring finger protein 186 ISO (PMID:23896122) UniProtKB PMID:23896122 NCBI chr 1:18,770,083...18,772,399
Ensembl chr 1:19,813,784...19,814,467
JBrowse link
G UBE2D4 ubiquitin conjugating enzyme E2 D4 (putative) ISO (PMID:20061386) UniProtKB PMID:20061386 NCBI chr 7:40,295,047...40,324,705 JBrowse link
G UBE2S ubiquitin conjugating enzyme E2 S ISO (PMID:20061386) UniProtKB PMID:20061386 NCBI chr19:52,444,270...52,450,770
Ensembl chr19:61,133,934...61,140,786
JBrowse link
G UBE2T ubiquitin conjugating enzyme E2 T ISO (PMID:20061386) UniProtKB PMID:20061386 NCBI chr 1:177,929,298...177,939,027
Ensembl chr 1:182,227,166...182,236,712
JBrowse link
protein K33-linked ubiquitination term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KLHL20 kelch like family member 20 ISO (PMID:24768539) UniProtKB PMID:24768539 NCBI chr 1:149,232,858...149,303,357
Ensembl chr 1:152,937,835...153,008,239
JBrowse link
protein K48-linked ubiquitination term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AMFR autocrine motility factor receptor ISO (PMID:12847084), (PMID:24424410) ParkinsonsUK-UCL PMID:12847084, PMID:24424410 NCBI chr16:36,647,792...36,711,782
Ensembl chr16:55,780,633...55,843,744
JBrowse link
G ARIH2 ariadne RBR E3 ubiquitin protein ligase 2 ISO (PMID:16118314), (PMID:19340006) UniProtKB PMID:16118314, PMID:19340006 NCBI chr 3:48,844,161...48,910,183
Ensembl chr 3:49,926,453...49,991,924
JBrowse link
G BFAR bifunctional apoptosis regulator ISO (PMID:21068390) ParkinsonsUK-UCL PMID:21068390 NCBI chr16:13,558,912...13,597,023
Ensembl chr16:14,980,615...15,018,310
JBrowse link
G BTRC beta-transducin repeat containing E3 ubiquitin protein ligase ISO (MGI:6149282|PMID:29593216) MGI PMID:29593216 MGI:6149282 NCBI chr10:97,958,527...98,159,550
Ensembl chr10:101,431,318...101,632,496
JBrowse link
G CDC34 cell division cycle 34, ubiqiutin conjugating enzyme ISO (PMID:20061386) UniProtKB PMID:20061386 NCBI chr19:592,856...602,811
Ensembl chr19:502,766...512,173
JBrowse link
G CUL1 cullin 1 ISO (MGI:6149282|PMID:29593216) MGI PMID:29593216 MGI:6149282 NCBI chr 7:140,428,442...140,531,136
Ensembl chr 7:152,908,303...153,011,254
JBrowse link
G DTX3L deltex E3 ubiquitin ligase 3L ISO (PMID:26479788) UniProtKB PMID:26479788 NCBI chr 3:119,654,019...119,664,918
Ensembl chr 3:126,558,924...126,569,807
JBrowse link
G FBXO38 F-box protein 38 ISO (PMID:30487606) UniProt PMID:30487606 NCBI chr 5:143,814,446...143,873,919
Ensembl chr 5:149,834,109...149,881,903
JBrowse link
G HACE1 HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 ISO (PMID:22036506) UniProtKB PMID:22036506 NCBI chr 6:102,541,992...102,674,281
Ensembl chr 6:106,419,867...106,551,007
JBrowse link
G IFI27 interferon alpha inducible protein 27 ISO (PMID:27194766) UniProt PMID:27194766 NCBI chr14:74,742,775...74,748,820
Ensembl chr14:94,046,694...94,082,022
JBrowse link
G ITCH itchy E3 ubiquitin protein ligase ISO (PMID:19881509), (PMID:30328013)
(MGI:3774677|PMID:18246070)
UniProt
BHF-UCL
PMID:18246070, PMID:19881509, PMID:30328013 MGI:3774677 NCBI chr20:30,690,172...30,840,504
Ensembl chr20:31,852,203...31,971,945
JBrowse link
G KLHL3 kelch like family member 3 ISO (PMID:23576762) UniProtKB PMID:23576762 NCBI chr 5:133,005,563...133,276,087
Ensembl chr 5:139,147,793...139,248,919
JBrowse link
G MARCHF6 membrane associated ring-CH-type finger 6 ISO (PMID:15673284) UniProtKB PMID:15673284 NCBI chr 5:10,666,978...10,753,050
Ensembl chr 5:10,524,958...10,608,046
JBrowse link
G NEDD4L NEDD4 like E3 ubiquitin protein ligase ISO (PMID:21463633) BHF-UCL PMID:21463633 NCBI chr18:51,428,077...51,792,995
Ensembl chr18:54,867,149...55,123,423
JBrowse link
G PELI1 pellino E3 ubiquitin protein ligase 1 ISO (PMID:29883609)
(MGI:5291872|PMID:21874024)
UniProtKB
MGI
PMID:21874024, PMID:29883609 MGI:5291872 NCBI chr2A:64,160,362...64,213,200
Ensembl chr2A:65,284,480...65,336,339
JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase ISO (PMID:21376232), (PMID:23858059) ParkinsonsUK-UCL PMID:21376232, PMID:23858059 NCBI chr 6:159,293,016...160,679,106
Ensembl chr 6:164,314,990...165,678,770
JBrowse link
G RBX1 ring-box 1 ISO (MGI:6149282|PMID:29593216) MGI PMID:29593216 MGI:6149282 NCBI chr22:21,845,351...21,866,627
Ensembl chr22:39,941,405...39,962,175
JBrowse link
G RFFL ring finger and FYVE like domain containing E3 ubiquitin protein ligase ISO (PMID:18450452), (PMID:22609986) UniProtKB PMID:18450452, PMID:22609986 NCBI chr17:21,696,808...21,779,878
Ensembl chr17:22,035,643...22,069,546
JBrowse link
G RNF115 ring finger protein 115 ISO (MGI:5582879|PMID:23418353) UniProt PMID:23418353 MGI:5582879 NCBI chr 1:121,936,054...122,016,273
Ensembl chr 1:113,651,728...113,733,788
JBrowse link
G RNF146 ring finger protein 146 ISO (PMID:21478859) UniProtKB PMID:21478859 NCBI chr 6:125,057,312...125,079,096
Ensembl chr 6:129,190,562...129,191,733
JBrowse link
G RNF152 ring finger protein 152 ISO (PMID:21203937) UniProtKB PMID:21203937 NCBI chr18:55,180,955...55,264,164
Ensembl chr18:58,507,684...58,508,295
JBrowse link
G RNF187 ring finger protein 187 ISO (PMID:20852630) UniProtKB PMID:20852630 NCBI chr 1:203,889,146...203,896,884 JBrowse link
G RNF216 ring finger protein 216 ISO (PMID:19893624) UniProtKB PMID:19893624 NCBI chr 7:5,872,118...6,037,073
Ensembl chr 7:5,891,909...6,051,979
JBrowse link
G RNF34 ring finger protein 34 ISO (PMID:25012219) UniProtKB PMID:25012219 NCBI chr12:118,998,436...119,022,823 JBrowse link
G RNF4 ring finger protein 4 ISO PMID:18408734 UniProt PMID:18408734 RGD:8553731 NCBI chr 4:2,614,918...2,661,785
Ensembl chr 4:2,540,612...2,563,937
JBrowse link
G RNF5 ring finger protein 5 ISO (PMID:19285439) UniProtKB PMID:19285439 NCBI chr 6:31,825,799...31,828,188 JBrowse link
G RNF6 ring finger protein 6 ISO (MGI:3603857|PMID:16204183) UniProt PMID:16204183 MGI:3603857 NCBI chr13:7,505,669...7,515,542
Ensembl chr13:25,854,765...25,864,629
JBrowse link
G RNF8 ring finger protein 8 ISO (PMID:21911360), (PMID:22266820), (PMID:22373579) UniProtKB PMID:21911360, PMID:22266820, PMID:22373579 NCBI chr 6:36,918,705...36,955,380
Ensembl chr 6:38,108,414...38,145,949
JBrowse link
G SKP1 S-phase kinase associated protein 1 ISO (MGI:6149282|PMID:29593216) MGI PMID:29593216 MGI:6149282 NCBI chr 5:129,560,086...129,580,188
Ensembl chr 5:135,713,085...135,729,653
JBrowse link
G SKP2 S-phase kinase associated protein 2 ISO (PMID:27194766) UniProt PMID:27194766 NCBI chr 5:74,179,608...74,211,563
Ensembl chr 5:79,461,018...79,492,311
JBrowse link
G SYVN1 synoviolin 1 ISO (PMID:14593114) ParkinsonsUK-UCL PMID:14593114 NCBI chr11:60,489,626...60,496,945
Ensembl chr11:63,829,138...63,834,364
JBrowse link
G TNFAIP3 TNF alpha induced protein 3 ISO (PMID:15258597) UniProtKB PMID:15258597 NCBI chr 6:135,617,465...135,634,085
Ensembl chr 6:139,705,255...139,720,819
JBrowse link
G TOPORS TOP1 binding arginine/serine rich protein, E3 ubiquitin ligase ISO (PMID:15247280) BHF-UCL PMID:15247280 NCBI chr 9:32,314,850...32,327,067
Ensembl chr 9:33,124,730...33,135,129
JBrowse link
G TRIM38 tripartite motif containing 38 ISO (MGI:5441682|PMID:22539786) MGI PMID:22539786 MGI:5441682 NCBI chr 6:25,796,278...25,818,610
Ensembl chr 6:26,454,051...26,475,842
JBrowse link
G TTC3 tetratricopeptide repeat domain 3 ISO (PMID:20059950) UniProtKB PMID:20059950 NCBI chr21:23,435,041...23,564,416
Ensembl chr21:36,803,826...36,917,527
JBrowse link
G UBE2A ubiquitin conjugating enzyme E2 A ISO (PMID:20061386) UniProtKB PMID:20061386 NCBI chr  X:108,606,271...108,617,000
Ensembl chr  X:119,034,235...119,049,655
JBrowse link
G UBE2B ubiquitin conjugating enzyme E2 B ISO (PMID:20061386) UniProtKB PMID:20061386 NCBI chr 5:129,775,011...129,794,853
Ensembl chr 5:135,925,217...135,944,609
JBrowse link
G UBE2C ubiquitin conjugating enzyme E2 C ISO (PMID:20061386) UniProtKB PMID:20061386 NCBI chr20:42,152,219...42,156,246
Ensembl chr20:43,239,382...43,243,464
JBrowse link
G UBE2D1 ubiquitin conjugating enzyme E2 D1 ISO (PMID:20061386) UniProtKB PMID:20061386 NCBI chr10:54,867,346...54,903,125
Ensembl chr10:57,087,811...57,123,581
JBrowse link
G UBE2D2 ubiquitin conjugating enzyme E2 D2 ISO (PMID:20061386) UniProtKB PMID:20061386 NCBI chr 5:134,927,150...134,995,298
Ensembl chr 5:141,048,385...141,115,842
JBrowse link
G UBE2D3 ubiquitin conjugating enzyme E2 D3 ISO (PMID:20061386) UniProtKB PMID:20061386 NCBI chr 4:95,218,319...95,293,053 JBrowse link
G UBE2D4 ubiquitin conjugating enzyme E2 D4 (putative) ISO (PMID:20061386) UniProtKB PMID:20061386 NCBI chr 7:40,295,047...40,324,705 JBrowse link
G UBE2E1 ubiquitin conjugating enzyme E2 E1 ISO (PMID:20061386) UniProtKB PMID:20061386 NCBI chr 3:23,719,632...23,803,302
Ensembl chr 3:24,045,747...24,127,820
JBrowse link
G UBE2E2 ubiquitin conjugating enzyme E2 E2 ISO (PMID:20061386) UniProtKB PMID:20061386 NCBI chr 3:23,121,699...23,502,329
Ensembl chr 3:23,446,158...23,825,277
JBrowse link
G UBE2E3 ubiquitin conjugating enzyme E2 E3 ISO (PMID:20061386) UniProtKB PMID:20061386 NCBI chr2B:68,245,028...68,328,059
Ensembl chr2B:186,057,033...186,139,384
JBrowse link
G UBE2G1 ubiquitin conjugating enzyme E2 G1 ISO (PMID:14593114), (PMID:20061386)
(MGI:5634892|PMID:12847084)
ParkinsonsUK-UCL PMID:12847084, PMID:14593114, PMID:20061386 MGI:5634892 NCBI chr17:4,321,294...4,416,936
Ensembl chr17:4,312,625...4,351,697
JBrowse link
G UBE2G2 ubiquitin conjugating enzyme E2 G2 ISO (PMID:20061386) UniProtKB PMID:20061386 NCBI chr21:31,062,516...31,095,044
Ensembl chr21:44,355,235...44,388,373
JBrowse link
G UBE2H ubiquitin conjugating enzyme E2 H ISO (PMID:20061386) UniProtKB PMID:20061386 NCBI chr 7:121,796,629...121,917,981
Ensembl chr 7:134,318,166...134,437,295
JBrowse link
G UBE2K ubiquitin conjugating enzyme E2 K ISO (PMID:20061386) UniProtKB PMID:20061386 NCBI chr 4:34,026,942...34,111,923
Ensembl chr 4:39,877,966...39,960,397
JBrowse link
G UBE2Q2 ubiquitin conjugating enzyme E2 Q2 ISO (PMID:20061386) UniProtKB PMID:20061386 NCBI chr15:54,754,642...54,814,264
Ensembl chr15:74,348,034...74,407,411
JBrowse link
G UBE2R2 ubiquitin conjugating enzyme E2 R2 ISO (PMID:20061386) UniProtKB PMID:20061386 NCBI chr 9:33,655,690...33,758,587 JBrowse link
G UBE2T ubiquitin conjugating enzyme E2 T ISO (PMID:20061386) UniProtKB PMID:20061386 NCBI chr 1:177,929,298...177,939,027
Ensembl chr 1:182,227,166...182,236,712
JBrowse link
G UBE3A ubiquitin protein ligase E3A ISO (PMID:12890688) UniProtKB PMID:12890688 NCBI chr15:4,494,029...4,595,415
Ensembl chr15:22,747,075...22,825,459
JBrowse link
G UBR5 ubiquitin protein ligase E3 component n-recognin 5 ISO (PMID:28689657) FlyBase PMID:28689657 NCBI chr 8:98,904,557...99,064,121
Ensembl chr 8:101,067,435...101,224,913
JBrowse link
G ZNRF1 zinc and ring finger 1 ISO (MGI:5306704|PMID:22057101) UniProt PMID:22057101 MGI:5306704 NCBI chr16:55,567,875...55,679,524
Ensembl chr16:74,920,141...75,030,933
JBrowse link
protein K6-linked ubiquitination term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BARD1 BRCA1 associated RING domain 1 ISO (PMID:12890688), (PMID:20351172) UniProtKB PMID:12890688, PMID:20351172 NCBI chr2B:101,984,287...102,068,523
Ensembl chr2B:220,456,972...220,541,145
JBrowse link
G BRCA1 BRCA1 DNA repair associated ISO (PMID:12890688), (PMID:20351172) UniProtKB PMID:12890688, PMID:20351172 NCBI chr17:14,197,946...14,279,064
Ensembl chr17:14,428,526...14,506,815
JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase ISO (PMID:25621951) UniProtKB PMID:25621951 NCBI chr 6:159,293,016...160,679,106
Ensembl chr 6:164,314,990...165,678,770
JBrowse link
G RNF4 ring finger protein 4 ISO PMID:18408734 UniProt PMID:18408734 RGD:8553731 NCBI chr 4:2,614,918...2,661,785
Ensembl chr 4:2,540,612...2,563,937
JBrowse link
G RNF6 ring finger protein 6 ISO (PMID:19345326) UniProtKB PMID:19345326 NCBI chr13:7,505,669...7,515,542
Ensembl chr13:25,854,765...25,864,629
JBrowse link
G UBE2D4 ubiquitin conjugating enzyme E2 D4 (putative) ISO (PMID:20061386) UniProtKB PMID:20061386 NCBI chr 7:40,295,047...40,324,705 JBrowse link
G UBE2S ubiquitin conjugating enzyme E2 S ISO (PMID:20061386) UniProtKB PMID:20061386 NCBI chr19:52,444,270...52,450,770
Ensembl chr19:61,133,934...61,140,786
JBrowse link
G UBE2T ubiquitin conjugating enzyme E2 T ISO (PMID:20061386) UniProtKB PMID:20061386 NCBI chr 1:177,929,298...177,939,027
Ensembl chr 1:182,227,166...182,236,712
JBrowse link
protein K63-linked ubiquitination term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARIH2 ariadne RBR E3 ubiquitin protein ligase 2 ISO (PMID:19340006) UniProtKB PMID:19340006 NCBI chr 3:48,844,161...48,910,183
Ensembl chr 3:49,926,453...49,991,924
JBrowse link
G BFAR bifunctional apoptosis regulator ISO (PMID:21068390) ParkinsonsUK-UCL PMID:21068390 NCBI chr16:13,558,912...13,597,023
Ensembl chr16:14,980,615...15,018,310
JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A ISO (PMID:18305112) UniProtKB PMID:18305112 NCBI chr 9:21,803,862...21,831,322 JBrowse link
G HECTD1 HECT domain E3 ubiquitin protein ligase 1 ISO (MGI:5427282|PMID:22431752) MGI PMID:22431752 MGI:5427282 NCBI chr14:11,871,973...11,979,548
Ensembl chr14:30,070,567...30,176,915
JBrowse link
G ITCH itchy E3 ubiquitin protein ligase ISO (PMID:18718448), (PMID:19592251) UniProtKB PMID:18718448, PMID:19592251 NCBI chr20:30,690,172...30,840,504
Ensembl chr20:31,852,203...31,971,945
JBrowse link
G MAGEL2 MAGE family member L2 ISO (PMID:23452853) UniProtKB PMID:23452853 NCBI chr15:6,017,523...6,021,849
Ensembl chr15:21,134,857...21,138,576
JBrowse link
G NEDD4 NEDD4 E3 ubiquitin protein ligase ISO PMID:20159449 UniProt PMID:20159449 RGD:8554407 NCBI chr15:34,798,880...34,963,823
Ensembl chr15:53,118,411...53,283,076
JBrowse link
G PELI1 pellino E3 ubiquitin protein ligase 1 ISO (PMID:29883609) UniProtKB PMID:29883609 NCBI chr2A:64,160,362...64,213,200
Ensembl chr2A:65,284,480...65,336,339
JBrowse link
G PELI3 pellino E3 ubiquitin protein ligase family member 3 ISO (MGI:5562512|PMID:23892723) MGI PMID:23892723 MGI:5562512 NCBI chr11:61,824,463...61,834,930
Ensembl chr11:65,148,441...65,159,211
JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase ISO (PMID:15728840), (PMID:17314283), (PMID:19880420), (PMID:25621951) UniProtKB PMID:15728840, PMID:17314283, PMID:19880420, PMID:25621951 NCBI chr 6:159,293,016...160,679,106
Ensembl chr 6:164,314,990...165,678,770
JBrowse link
G PRPF19 pre-mRNA processing factor 19 ISO (PMID:20595234), (PMID:24332808) UniProtKB PMID:20595234, PMID:24332808 NCBI chr11:56,153,965...56,169,821
Ensembl chr11:59,595,120...59,607,828
JBrowse link
G RNF115 ring finger protein 115 ISO (MGI:5582879|PMID:23418353) UniProt PMID:23418353 MGI:5582879 NCBI chr 1:121,936,054...122,016,273
Ensembl chr 1:113,651,728...113,733,788
JBrowse link
G RNF135 ring finger protein 135 ISO (PMID:31006531) UniProt PMID:31006531 NCBI chr17:25,843,447...25,869,874 JBrowse link
G RNF152 ring finger protein 152 ISO (PMID:25936802) UniProtKB PMID:25936802 NCBI chr18:55,180,955...55,264,164
Ensembl chr18:58,507,684...58,508,295
JBrowse link
G RNF168 ring finger protein 168 ISO (PMID:22266820) UniProtKB PMID:22266820 NCBI chr 3:193,814,785...193,848,620
Ensembl chr 3:203,756,589...203,790,687
JBrowse link
G RNF186 ring finger protein 186 ISO (PMID:23896122) UniProtKB PMID:23896122 NCBI chr 1:18,770,083...18,772,399
Ensembl chr 1:19,813,784...19,814,467
JBrowse link
G RNF4 ring finger protein 4 ISO PMID:18408734 UniProt PMID:18408734 RGD:8553731 NCBI chr 4:2,614,918...2,661,785
Ensembl chr 4:2,540,612...2,563,937
JBrowse link
G RNF5 ring finger protein 5 ISO (PMID:19269966) UniProtKB PMID:19269966 NCBI chr 6:31,825,799...31,828,188 JBrowse link
G RNF8 ring finger protein 8 ISO (PMID:21911360) UniProtKB PMID:21911360 NCBI chr 6:36,918,705...36,955,380
Ensembl chr 6:38,108,414...38,145,949
JBrowse link
G STUB1 STIP1 homology and U-box containing protein 1 ISO (PMID:16307917) UniProtKB PMID:16307917 Ensembl chr16:694,414...696,682 JBrowse link
G TRAF2 TNF receptor associated factor 2 ISO (PMID:15258597), (PMID:20577214) UniProtKB PMID:15258597, PMID:20577214 NCBI chr 9:107,938,935...107,984,797
Ensembl chr 9:136,917,358...136,955,331
JBrowse link
G TRAF3IP2 TRAF3 interacting protein 2 ISO (PMID:19825828) UniProt PMID:19825828 NCBI chr 6:109,367,333...109,414,601
Ensembl chr 6:113,444,005...113,485,533
JBrowse link
G TRAF6 TNF receptor associated factor 6 ISO (PMID:19713527), (PMID:21068390)
(MGI:3610521|PMID:16252010)
(PMID:17135271), (PMID:19675569)
UniProtKB
UniProt
PMID:16252010, PMID:17135271, PMID:19675569, PMID:19713527, PMID:21068390 MGI:3610521 NCBI chr11:36,457,633...36,483,616
Ensembl chr11:36,335,609...36,356,334
JBrowse link
G TRIM27 tripartite motif containing 27 ISO (PMID:23452853) UniProtKB PMID:23452853 NCBI chr 6:28,722,505...28,743,484
Ensembl chr 6:29,390,423...29,411,308
JBrowse link
G TRIM5 tripartite motif containing 5 ISO (PMID:21512573) UniProtKB PMID:21512573 NCBI chr11:5,798,336...5,819,876
Ensembl chr11:5,479,033...5,500,758
JBrowse link
G TRIM56 tripartite motif containing 56 ISO (MGI:4849871|PMID:21074459) UniProt PMID:21074459 MGI:4849871 NCBI chr 7:93,225,830...93,231,127
Ensembl chr 7:106,469,474...106,471,741
JBrowse link
G UBE2B ubiquitin conjugating enzyme E2 B ISO (PMID:20061386) UniProtKB PMID:20061386 NCBI chr 5:129,775,011...129,794,853
Ensembl chr 5:135,925,217...135,944,609
JBrowse link
G UBE2D4 ubiquitin conjugating enzyme E2 D4 (putative) ISO (PMID:20061386) UniProtKB PMID:20061386 NCBI chr 7:40,295,047...40,324,705 JBrowse link
G UBE2E2 ubiquitin conjugating enzyme E2 E2 ISO (PMID:20061386) UniProtKB PMID:20061386 NCBI chr 3:23,121,699...23,502,329
Ensembl chr 3:23,446,158...23,825,277
JBrowse link
G UBE2E3 ubiquitin conjugating enzyme E2 E3 ISO (PMID:20061386) UniProtKB PMID:20061386 NCBI chr2B:68,245,028...68,328,059
Ensembl chr2B:186,057,033...186,139,384
JBrowse link
G UBE2G1 ubiquitin conjugating enzyme E2 G1 ISO (PMID:20061386) UniProtKB PMID:20061386 NCBI chr17:4,321,294...4,416,936
Ensembl chr17:4,312,625...4,351,697
JBrowse link
G UBE2N ubiquitin conjugating enzyme E2 N ISO (PMID:16307917), (PMID:20061386), (PMID:21512573), (PMID:31006531)
(MGI:5896692|PMID:28039360), (MGI:6148454|PMID:22424771)
(PMID:25936802)
UniProt
UniProtKB
PMID:16307917, PMID:20061386, PMID:21512573, PMID:22424771, PMID:25936802, PMID:28039360, PMID:31006531 MGI:5896692, MGI:6148454 NCBI chr12:90,951,446...90,984,075 JBrowse link
G UBE2O ubiquitin conjugating enzyme E2 O ISO (PMID:23452853) UniProtKB PMID:23452853 NCBI chr17:70,337,622...70,400,967
Ensembl chr17:75,889,533...75,952,051
JBrowse link
G UBE2S ubiquitin conjugating enzyme E2 S ISO (PMID:20061386) UniProtKB PMID:20061386 NCBI chr19:52,444,270...52,450,770
Ensembl chr19:61,133,934...61,140,786
JBrowse link
G UBE2T ubiquitin conjugating enzyme E2 T ISO (PMID:20061386) UniProtKB PMID:20061386 NCBI chr 1:177,929,298...177,939,027
Ensembl chr 1:182,227,166...182,236,712
JBrowse link
G UBE2V1 ubiquitin conjugating enzyme E2 V1 ISO (PMID:16307917), (PMID:21512573), (PMID:31006531) UniProt PMID:16307917, PMID:21512573, PMID:31006531 NCBI chr20:46,422,383...46,457,295
Ensembl chr20:47,539,899...47,574,328
JBrowse link
G WWP2 WW domain containing E3 ubiquitin protein ligase 2 ISO (MGI:4821930|PMID:19997087) UniProt PMID:19997087 MGI:4821930 NCBI chr16:50,142,402...50,322,052
Ensembl chr16:69,525,246...69,703,831
JBrowse link
G ZFP91 ZFP91 zinc finger protein, atypical E3 ubiquitin ligase ISO (PMID:20682767) UniProtKB PMID:20682767 NCBI chr11:53,833,437...53,875,435 JBrowse link
protein linear polyubiquitination term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RBCK1 RANBP2-type and C3HC4-type zinc finger containing 1 ISO (PMID:21455173), (PMID:21455180), (PMID:21455181), (PMID:23453807) UniProtKB PMID:21455173, PMID:21455180, PMID:21455181, PMID:23453807 NCBI chr20:615,987...639,366
Ensembl chr20:386,569...409,580
JBrowse link
G RNF31 ring finger protein 31 ISO (PMID:21455173), (PMID:21455180), (PMID:21455181), (PMID:23453807) UniProtKB PMID:21455173, PMID:21455180, PMID:21455181, PMID:23453807 NCBI chr14:4,923,391...4,936,959 JBrowse link
G SHARPIN SHANK associated RH domain interactor ISO (PMID:21455173), (PMID:21455180), (PMID:21455181) UniProtKB PMID:21455173, PMID:21455180, PMID:21455181 NCBI chr 8:140,865,009...140,870,580
Ensembl chr 8:143,854,902...143,862,888
JBrowse link
regulation of protein K63-linked ubiquitination term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SASH1 SAM and SH3 domain containing 1 ISO (PMID:23776175) MGI PMID:23776175 NCBI chr 6:146,154,178...146,368,101
Ensembl chr 6:150,863,677...151,075,816
JBrowse link
regulation of protein polyubiquitination term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FOXF2 forkhead box F2 ISO (PMID:29374064) UniProt PMID:29374064 NCBI chr 6:1,209,899...1,215,970 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12567
    metabolic process 7893
      cellular metabolic process 7226
        cellular macromolecule metabolic process 5557
          cellular protein metabolic process 3450
            cellular protein modification process 2751
              protein modification by small protein conjugation or removal 662
                protein modification by small protein conjugation 566
                  protein ubiquitination 511
                    protein polyubiquitination 184
                      negative regulation of protein polyubiquitination + 10
                      positive regulation of protein polyubiquitination + 15
                      protein K11-linked ubiquitination 27
                      protein K27-linked ubiquitination 4
                      protein K29-linked ubiquitination 5
                      protein K33-linked ubiquitination 1
                      protein K48-linked ubiquitination + 59
                      protein K6-linked ubiquitination 8
                      protein K63-linked ubiquitination + 49
                      protein linear polyubiquitination + 5
                      protein polyubiquitination involved in nucleus-associated proteasomal ubiquitin-dependent protein catabolic process 0
                      regulation of protein polyubiquitination + 27
Path 2
Term Annotations click to browse term
  biological_process 12567
    metabolic process 7893
      organic substance metabolic process 7572
        macromolecule metabolic process 6504
          protein metabolic process 3827
            protein modification process 2751
              cellular protein modification process 2751
                protein modification by small protein conjugation or removal 662
                  protein modification by small protein conjugation 566
                    protein ubiquitination 511
                      protein polyubiquitination 184
                        negative regulation of protein polyubiquitination + 10
                        positive regulation of protein polyubiquitination + 15
                        protein K11-linked ubiquitination 27
                        protein K27-linked ubiquitination 4
                        protein K29-linked ubiquitination 5
                        protein K33-linked ubiquitination 1
                        protein K48-linked ubiquitination + 59
                        protein K6-linked ubiquitination 8
                        protein K63-linked ubiquitination + 49
                        protein linear polyubiquitination + 5
                        protein polyubiquitination involved in nucleus-associated proteasomal ubiquitin-dependent protein catabolic process 0
                        regulation of protein polyubiquitination + 27
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.