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ONTOLOGY REPORT - ANNOTATIONS


Term:mitochondrial fission
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Accession:GO:0000266 term browser browse the term
Definition:The division of a mitochondrion within a cell to form two or more separate mitochondrial compartments.
Synonyms:exact_synonym: mitochondrial division
 related_synonym: mitochondrial proliferation


show annotations for term's descendants           Sort by:
 
mitochondrial fission term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cox10 cytochrome c oxidase assembly factor heme A:farnesyltransferase COX10 ISO MGI:MGI:1931135|MGI:MGI:3605782 (MGI:MGI:3604933|PMID:16103131) RGD PMID:16103131 MGI:MGI:3604933 NCBI chr10:50,439,778...50,563,920
Ensembl chr10:50,439,782...50,574,539
JBrowse link
G Dnm1 dynamin 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:11,338,081...11,382,043
Ensembl chr 3:11,338,083...11,382,043
JBrowse link
G Dnm1l dynamin 1-like ISS
IBA
ISO
GO_REF:0000024
PMID:21873635
(MGI:MGI:4421613|PMID:20038678), (MGI:MGI:5319417|PMID:22493254), (MGI:MGI:5508698|PMID:23283981)
(PMID:23349293), (PMID:23530241), (PMID:23921378), (PMID:26992161), (PMID:27145208)
UniProt
RGD
PMID:20038678, PMID:22493254, PMID:23283981, PMID:23349293, PMID:23530241, PMID:23921378, PMID:26992161, PMID:27145208, PMID:21873635 GO_REF:0000024, MGI:MGI:4421613, MGI:MGI:5319417, MGI:MGI:5508698, RGD:13792537 NCBI chr11:88,830,968...88,882,271
Ensembl chr11:88,830,957...88,880,198
JBrowse link
G Dnm2 dynamin 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:22,458,869...22,540,649
Ensembl chr 8:22,458,899...22,540,524
JBrowse link
G Dnm3 dynamin 3 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr13:79,906,711...80,379,967
Ensembl chr13:79,910,382...80,379,929
JBrowse link
G Fis1 fission, mitochondrial 1 ISO
IBA
ISS
(MGI:MGI:5508698|PMID:23283981)
PMID:21873635
(PMID:16118244), (PMID:18845145), (PMID:19864424)
GO_REF:0000024
RGD
UniProt
PMID:16118244, PMID:18845145, PMID:19864424, PMID:23283981, PMID:21873635 GO_REF:0000024, MGI:MGI:5508698, RGD:13792537 NCBI chr12:22,750,485...22,765,324
Ensembl chr12:22,750,485...22,765,308
JBrowse link
G Gdap1 ganglioside-induced differentiation-associated-protein 1 ISO
IBA
ISS
(PMID:15772096)
PMID:21873635
GO_REF:0000024
RGD
UniProt
PMID:15772096, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 5:1,328,963...1,347,946
Ensembl chr 5:1,328,913...1,347,921
JBrowse link
G Ggnbp1 gametogenetin binding protein 1 ISO
ISS
(MGI:MGI:3848864|PMID:19208545)
GO_REF:0000024
RGD
UniProt
PMID:19208545 GO_REF:0000024, MGI:MGI:3848864 NCBI chr20:5,618,973...5,625,320
Ensembl chr20:5,619,012...5,625,320
JBrowse link
G LOC102556337 mitochondrial fission factor-like ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 9:90,880,586...90,908,848
Ensembl chr 9:90,880,614...90,908,852
JBrowse link
G Lpin1 lipin 1 ISO (MGI:MGI:4943609|PMID:21397848) RGD PMID:21397848 MGI:MGI:4943609 NCBI chr 6:41,796,214...41,905,149
Ensembl chr 6:41,799,749...41,870,046
JBrowse link
G Mff mitochondrial fission factor ISS
ISO
GO_REF:0000024
(MGI:MGI:5508698|PMID:23283981), (MGI:MGI:6200588|PMID:30059978)
UniProt
RGD
PMID:23283981, PMID:30059978 GO_REF:0000024, MGI:MGI:5508698, MGI:MGI:6200588 NCBI chr 9:88,490,280...88,518,517
Ensembl chr 9:88,493,593...88,517,827
JBrowse link
G Mief1 mitochondrial elongation factor 1 ISO
ISS
(PMID:21701560)
GO_REF:0000024
RGD
UniProt
PMID:21701560 GO_REF:0000024 NCBI chr 7:121,462,962...121,478,545
Ensembl chr 7:121,462,966...121,478,546
JBrowse link
G Mtfp1 mitochondrial fission process 1 ISO
IBA
(PMID:15985469)
PMID:21873635
RGD PMID:15985469, PMID:21873635 RGD:13792537 NCBI chr14:84,330,223...84,334,063
Ensembl chr14:84,330,218...84,334,066
JBrowse link
G Mtfr1 mitochondrial fission regulator 1 ISS
IBA
GO_REF:0000024
PMID:21873635
UniProt PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 2:104,005,696...104,040,914
Ensembl chr 2:104,020,955...104,039,198
JBrowse link
G Mtfr1l mitochondrial fission regulator 1-like IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:152,736,580...152,746,683
Ensembl chr 5:152,736,585...152,746,588
JBrowse link
G Mtfr2 mitochondrial fission regulator 2 ISO
IBA
(MGI:MGI:5320275|PMID:20568109)
PMID:21873635
RGD PMID:20568109, PMID:21873635 MGI:MGI:5320275, RGD:13792537 NCBI chr 1:15,834,779...15,850,424
Ensembl chr 1:15,782,477...15,860,624
JBrowse link
G Mul1 mitochondrial E3 ubiquitin protein ligase 1 ISO (PMID:18207745) RGD PMID:18207745 NCBI chr 5:156,855,105...156,864,517
Ensembl chr 5:156,850,206...156,864,517
JBrowse link
G Mx1 myxovirus (influenza virus) resistance 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr11:37,891,150...37,916,775
Ensembl chr11:37,891,156...37,914,983
JBrowse link
G Mx2 MX dynamin like GTPase 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr11:38,035,306...38,066,185
Ensembl chr11:38,035,450...38,059,950
JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr11:74,717,600...74,793,902
Ensembl chr11:74,720,254...74,793,803
JBrowse link
G Ppp2r2b protein phosphatase 2, regulatory subunit B, beta IDA RGD PMID:18940801 RGD:2314538 NCBI chr18:36,985,709...37,421,383
Ensembl chr18:36,985,714...37,245,809
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase ISS GO_REF:0000024 ParkinsonsUK-UCL GO_REF:0000024 NCBI chr 1:48,880,015...50,069,998 JBrowse link
establishment of protein localization to mitochondrial membrane involved in mitochondrial fission term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ap3b1 adaptor related protein complex 3 subunit beta 1 ISO (MGI:MGI:1928195|PMID:11058094) RGD PMID:11058094 MGI:MGI:1928195 NCBI chr 2:24,022,815...24,227,522
Ensembl chr 2:24,024,791...24,226,224
JBrowse link
G Mtch2 mitochondrial carrier 2 ISO MGI:MGI:2449949|MGI:MGI:5566664 (MGI:MGI:5662300|PMID:26219591) RGD PMID:26219591 MGI:MGI:5662300 NCBI chr 3:79,678,141...79,695,356
Ensembl chr 3:79,678,201...79,694,006
JBrowse link
mitochondrial membrane fission term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnm1l dynamin 1-like ISO (PMID:11514614), (PMID:27301544), (PMID:27328748) RGD PMID:11514614, PMID:27301544, PMID:27328748 NCBI chr11:88,830,968...88,882,271
Ensembl chr11:88,830,957...88,880,198
JBrowse link
G Slc25a46 solute carrier family 25, member 46 ISO
ISS
(PMID:26168012)
GO_REF:0000024
RGD
UniProt
PMID:26168012 GO_REF:0000024 NCBI chr18:24,369,104...24,397,412
Ensembl chr18:24,369,125...24,397,551
JBrowse link
negative regulation of mitochondrial fission term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mapt microtubule-associated protein tau ISO
IEA
(PMID:22920254)
GO_REF:0000107
RGD
Ensembl
PMID:22920254 GO_REF:0000107 NCBI chr10:92,289,002...92,386,517
Ensembl chr10:92,288,910...92,386,517
JBrowse link
G Mfn1 mitofusin 1 IMP RGD PMID:18832378 RGD:12738368 NCBI chr 2:118,929,738...118,971,689
Ensembl chr 2:118,929,738...118,973,698
JBrowse link
G Mfn2 mitofusin 2 IMP RGD PMID:28478070 RGD:12910733 NCBI chr 5:164,684,244...164,715,414
Ensembl chr 5:164,684,509...164,714,145
JBrowse link
G Pink1 PTEN induced kinase 1 ISO (PMID:19279012) RGD PMID:19279012 NCBI chr 5:156,677,146...156,689,258
Ensembl chr 5:156,677,146...156,689,415
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha IMP RGD PMID:23449689 RGD:10059694 NCBI chr14:63,095,291...63,190,688
Ensembl chr14:63,095,720...63,187,009
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase IMP RGD PMID:24096089 RGD:10413842 NCBI chr 1:48,880,015...50,069,998 JBrowse link
G RGD1311251 similar to RIKEN cDNA 4930550C14 ISS
ISO
GO_REF:0000024
(MGI:MGI:6200588|PMID:30059978)
UniProt
RGD
PMID:30059978 GO_REF:0000024, MGI:MGI:6200588 NCBI chr 8:57,983,168...58,012,474
Ensembl chr 8:57,983,556...58,011,962
JBrowse link
positive regulation of mitochondrial fission term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bnip3 BCL2 interacting protein 3 ISO (PMID:20436456) RGD PMID:20436456 NCBI chr 1:211,248,098...211,265,282
Ensembl chr 1:211,248,098...211,265,282
JBrowse link
G Dcn decorin ISO UniProtKB:P35968 (PMID:23798385) RGD PMID:23798385 NCBI chr 7:38,742,250...38,782,282
Ensembl chr 7:38,742,051...38,782,323
JBrowse link
G Ddhd1 DDHD domain containing 1 ISO (PMID:24599962) RGD PMID:24599962 NCBI chr15:19,963,639...20,032,263
Ensembl chr15:19,965,187...20,032,191
JBrowse link
G Ddhd2 DDHD domain containing 2 ISO (MGI:MGI:5581382|PMID:24599962) RGD PMID:24599962 MGI:MGI:5581382 NCBI chr16:71,090,096...71,120,713
Ensembl chr16:71,090,045...71,118,552
JBrowse link
G Dnm1l dynamin 1-like ISO
IMP
(PMID:19279012) RGD PMID:19279012, PMID:17443673 RGD:12738363 NCBI chr11:88,830,968...88,882,271
Ensembl chr11:88,830,957...88,880,198
JBrowse link
G Fis1 fission, mitochondrial 1 IMP
ISS
ISO
GO_REF:0000024
(PMID:23283981)
UniProt
RGD
PMID:23283981, PMID:17443673, PMID:15979461 GO_REF:0000024, RGD:12738363, RGD:12738370 NCBI chr12:22,750,485...22,765,324
Ensembl chr12:22,750,485...22,765,308
JBrowse link
G Kdr kinase insert domain receptor ISO
IEA
UniProtKB:P07585 (PMID:23798385)
GO_REF:0000107
RGD
Ensembl
PMID:23798385 GO_REF:0000107 NCBI chr14:34,727,677...34,787,127
Ensembl chr14:34,727,623...34,787,183
JBrowse link
G LOC102556337 mitochondrial fission factor-like ISS
IBA
GO_REF:0000024
PMID:21873635
UniProt PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 9:90,880,586...90,908,848
Ensembl chr 9:90,880,614...90,908,852
JBrowse link
G Marchf5 membrane associated ring-CH-type finger 5 ISO (PMID:20103533) RGD PMID:20103533 NCBI chr 1:255,842,642...255,864,131
Ensembl chr 1:255,842,783...255,863,142
JBrowse link
G Mcu mitochondrial calcium uniporter ISO (PMID:28388446) RGD PMID:28388446 NCBI chr20:29,037,452...29,199,224
Ensembl chr20:29,038,480...29,199,224
JBrowse link
G Mff mitochondrial fission factor IMP
IBA
ISO
ISS
PMID:21873635
(PMID:23283981), (PMID:23530241)
GO_REF:0000024
RGD
UniProt
PMID:23283981, PMID:23530241, PMID:23867156, PMID:21873635 GO_REF:0000024, RGD:12879458, RGD:13792537 NCBI chr 9:88,490,280...88,518,517
Ensembl chr 9:88,493,593...88,517,827
JBrowse link
G Mief1 mitochondrial elongation factor 1 ISO
IBA
ISS
(MGI:MGI:5508698|PMID:23283981)
PMID:21873635
(PMID:23283981), (PMID:23530241)
GO_REF:0000024
RGD
UniProt
PMID:23283981, PMID:23530241, PMID:21873635 GO_REF:0000024, MGI:MGI:5508698, RGD:13792537 NCBI chr 7:121,462,962...121,478,545
Ensembl chr 7:121,462,966...121,478,546
JBrowse link
G Mief2 mitochondrial elongation factor 2 ISO
IBA
(MGI:MGI:5508698|PMID:23283981)
PMID:21873635
(PMID:23283981), (PMID:23530241)
RGD PMID:23283981, PMID:23530241, PMID:21873635 MGI:MGI:5508698, RGD:13792537 NCBI chr10:46,969,531...46,975,572
Ensembl chr10:46,972,038...46,974,806
JBrowse link
G Mul1 mitochondrial E3 ubiquitin protein ligase 1 ISO (PMID:19407830) RGD PMID:19407830 NCBI chr 5:156,855,105...156,864,517
Ensembl chr 5:156,850,206...156,864,517
JBrowse link
G Pink1 PTEN induced kinase 1 IMP
IBA
PMID:21873635 RGD
GO_Central
PMID:21613270, PMID:21873635 RGD:12903967, RGD:13792537 NCBI chr 5:156,677,146...156,689,258
Ensembl chr 5:156,677,146...156,689,415
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase ISS GO_REF:0000024 ParkinsonsUK-UCL GO_REF:0000024 NCBI chr 1:48,880,015...50,069,998 JBrowse link
G Spire1 spire-type actin nucleation factor 1 ISO (PMID:26305500)
(MGI:MGI:5698602|PMID:26305500)
RGD PMID:26305500 MGI:MGI:5698602 NCBI chr18:63,226,557...63,357,420
Ensembl chr18:63,226,557...63,357,298
JBrowse link
G Vps35 VPS35 retromer complex component ISO (PMID:26618722) RGD PMID:26618722 NCBI chr19:27,464,937...27,500,636
Ensembl chr19:27,464,937...27,500,636
JBrowse link
regulation of mitochondrial fission term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyrib CYFIP related Rac1 interactor B ISO (PMID:29059164)
(MGI:MGI:6383355|PMID:29059164)
RGD PMID:29059164 MGI:MGI:6383355 NCBI chr 7:104,514,566...104,641,875
Ensembl chr 7:104,516,391...104,556,419
JBrowse link
G Dhodh dihydroorotate dehydrogenase (quinone) IMP RGD PMID:16120318 RGD:2316230 NCBI chr19:42,066,103...42,087,906
Ensembl chr19:42,066,351...42,082,012
JBrowse link
G Inf2 inverted formin 2 ISO
IEA
(PMID:23349293)
GO_REF:0000107
RGD
Ensembl
PMID:23349293 GO_REF:0000107 NCBI chr 6:137,162,593...137,180,198
Ensembl chr 6:137,164,535...137,177,622
JBrowse link
G Marchf5 membrane associated ring-CH-type finger 5 ISO (PMID:16874301), (PMID:17606867) RGD PMID:16874301, PMID:17606867 NCBI chr 1:255,842,642...255,864,131
Ensembl chr 1:255,842,783...255,863,142
JBrowse link
G Myo19 myosin XIX ISO (PMID:25447992) RGD PMID:25447992 NCBI chr10:72,198,475...72,227,892
Ensembl chr10:72,197,977...72,227,462
JBrowse link
G Stat2 signal transducer and activator of transcription 2 ISO (PMID:26122121) RGD PMID:26122121 NCBI chr 7:2,691,064...2,707,530
Ensembl chr 7:2,691,369...2,707,741
JBrowse link
G Tmem135 transmembrane protein 135 ISO
ISS
(MGI:MGI:5811545|PMID:27863209)
GO_REF:0000024
RGD
UniProt
PMID:27863209 GO_REF:0000024, MGI:MGI:5811545 NCBI chr 1:152,886,496...153,096,225
Ensembl chr 1:152,886,996...153,096,269
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20027
    cellular process 18798
      cellular component organization or biogenesis 6789
        cellular component organization 6534
          organelle organization 4101
            organelle fission 500
              mitochondrial fission 47
                establishment of mitochondrion localization involved in mitochondrial fission + 0
                establishment of protein localization to mitochondrial membrane involved in mitochondrial fission 2
                mitochondrial DNA inheritance 0
                mitochondrial membrane fission 2
                mitochondrial nucleoid organization involved in mitochondrial fission 0
                negative regulation of mitochondrial fission 7
                positive regulation of mitochondrial fission 18
                regulation of mitochondrial fission + 29
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.