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ONTOLOGY REPORT - ANNOTATIONS


Term:THO complex
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Accession:GO:0000347 term browser browse the term
Definition:The THO complex is a nuclear complex that is required for transcription elongation through genes containing tandemly repeated DNA sequences. The THO complex is also part of the TREX (TRanscription EXport) complex that is involved in coupling transcription to export of mRNAs to the cytoplasm. In S. cerevisiae, it is composed of four subunits: Hpr1p, Tho2p, Thp1p, and Mft1p, while the human complex is composed of 7 subunits.


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THO complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Da2-19 uncharacterized LOC302729 JBrowse link X 48,196,789 48,213,506 RGD:13792537
G Thoc1 THO complex 1 JBrowse link 18 1,142,540 1,177,084 RGD:1624291
G Thoc2 THO complex 2 JBrowse link X 128,153,824 128,268,327 RGD:1624291
G Thoc5 THO complex 5 JBrowse link 14 85,138,219 85,171,729 RGD:1624291
G Thoc6 THO complex 6 JBrowse link 10 12,989,135 12,994,495 RGD:1624291
G Thoc7 THO complex 7 JBrowse link 15 12,569,235 12,584,101 RGD:1624291
THO complex part of transcription export complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Da2-19 uncharacterized LOC302729 JBrowse link X 48,196,789 48,213,506 RGD:13792537
G LOC679894 similar to THO complex subunit 2 (Tho2) JBrowse link 14 6,561,962 6,601,906 RGD:13792537
G Thoc1 THO complex 1 JBrowse link 18 1,142,540 1,177,084 RGD:1624291
G Thoc2 THO complex 2 JBrowse link X 128,153,824 128,268,327 RGD:1624291
RGD:13792537
G Thoc3 THO complex 3 JBrowse link 17 10,676,943 10,686,134 RGD:1624291
RGD:13792537
G Thoc5 THO complex 5 JBrowse link 14 85,138,219 85,171,729 RGD:1624291
RGD:13792537
G Thoc6 THO complex 6 JBrowse link 10 12,989,135 12,994,495 RGD:1624291
G Thoc7 THO complex 7 JBrowse link 15 12,569,235 12,584,101 RGD:1624291
RGD:13792537

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 19843
    protein-containing complex 5779
      THO complex 8
        THO complex part of transcription export complex 8
        nucleoplasmic THO complex 0
Path 2
Term Annotations click to browse term
  cellular_component 19843
    cellular anatomical entity 19457
      organelle 12557
        membrane-bounded organelle 10879
          intracellular membrane-bounded organelle 9976
            nucleus 6783
              THO complex 8
                THO complex part of transcription export complex 8
                nucleoplasmic THO complex 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.