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ONTOLOGY REPORT - ANNOTATIONS


Term:proteasome complex
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Accession:GO:0000502 term browser browse the term
Definition:A large multisubunit complex which catalyzes protein degradation, found in eukaryotes, archaea and some bacteria. In eukaryotes, this complex consists of the barrel shaped proteasome core complex and one or two associated proteins or complexes that act in regulating entry into or exit from the core.
Synonyms:exact_synonym: proteasome
 narrow_synonym: 26S proteasome


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proteasome complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G DNAJB2 DnaJ heat shock protein family (Hsp40) member B2 JBrowse link 37 25,826,496 25,834,011 RGD:13508589
G PSMD10 proteasome 26S subunit, non-ATPase 10 JBrowse link X 81,625,288 81,632,175 RGD:13508589
G PSMD7 proteasome 26S subunit, non-ATPase 7 JBrowse link 5 79,785,620 79,793,793 RGD:13508589
G UBE3A ubiquitin protein ligase E3A JBrowse link 3 35,347,034 35,442,329 RGD:13508589
G UBR1 ubiquitin protein ligase E3 component n-recognin 1 JBrowse link 30 9,869,769 10,006,994 RGD:13508589
G VCP valosin containing protein JBrowse link 11 51,636,986 51,651,749 RGD:13508589
G ZFAND2B zinc finger AN1-type containing 2B JBrowse link 37 25,757,454 25,760,366 RGD:13508589
cytosolic proteasome complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G LOC100687259 26S proteasome regulatory subunit 10B JBrowse link 32 35,814,756 35,816,311 RGD:13508589
G PSMC4 proteasome 26S subunit, ATPase 4 JBrowse link 1 113,548,351 113,557,725 RGD:13508589
G PSMC5 proteasome 26S subunit, ATPase 5 JBrowse link 9 11,783,422 11,787,624 RGD:13508589
G UBQLN4 ubiquilin 4 JBrowse link 7 41,764,209 41,778,457 RGD:13508589
nuclear proteasome complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PSMC5 proteasome 26S subunit, ATPase 5 JBrowse link 9 11,783,422 11,787,624 RGD:13508589
G PSMD12 proteasome 26S subunit, non-ATPase 12 JBrowse link 9 13,136,883 13,170,544 RGD:13508589
G UBQLN4 ubiquilin 4 JBrowse link 7 41,764,209 41,778,457 RGD:13508589
proteasome activator complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CNTD1 cyclin N-terminal domain containing 1 JBrowse link 9 20,214,310 20,222,938 RGD:13508589
G PSME1 proteasome activator subunit 1 JBrowse link 8 4,131,197 4,134,001 RGD:13508589
G PSME2 proteasome activator subunit 2 JBrowse link 8 4,137,247 4,141,380 RGD:13508589
G PSME3 proteasome activator subunit 3 JBrowse link 9 20,185,997 20,193,320 RGD:13508589
proteasome core complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G LOC102152879 proteasome subunit alpha type-1-like JBrowse link 30 24,114,023 24,116,951 RGD:13508589
G PSMA3 proteasome 20S subunit alpha 3 JBrowse link 8 33,616,735 33,642,434 RGD:13508589
G PSMA4 proteasome 20S subunit alpha 4 JBrowse link X 53,245,249 53,246,357 RGD:13508589
G PSMA5 proteasome 20S subunit alpha 5 JBrowse link 6 42,425,590 42,450,074 RGD:13508589
G PSMA6 proteasome 20S subunit alpha 6 JBrowse link 8 14,010,899 14,038,141 RGD:13508589
G PSMA7 proteasome 20S subunit alpha 7 JBrowse link 24 46,182,344 46,186,241 RGD:13508589
G PSMA8 proteasome 20S subunit alpha 8 JBrowse link 7 62,432,477 62,472,984 RGD:13508589
G PSMB1 proteasome 20S subunit beta 1 JBrowse link 12 72,440,224 72,456,304 RGD:13508589
G PSMB10 proteasome 20S subunit beta 10 JBrowse link 5 81,560,750 81,563,571 RGD:13508589
G PSMB2 proteasome 20S subunit beta 2 JBrowse link 15 6,511,281 6,544,859 RGD:13508589
G PSMB3 proteasome 20S subunit beta 3 JBrowse link 9 23,474,476 23,484,408 RGD:13508589
G PSMB4 proteasome 20S subunit beta 4 JBrowse link 17 60,461,208 60,463,604 RGD:13508589
G PSMB5 proteasome 20S subunit beta 5 JBrowse link 8 3,344,157 3,349,921 RGD:13508589
G PSMB6 proteasome 20S subunit beta 6 JBrowse link 5 31,776,286 31,778,789 RGD:13508589
G PSMB7 proteasome 20S subunit beta 7 JBrowse link 9 58,529,646 58,593,016 RGD:13508589
G PSMB8 proteasome 20S subunit beta 8 JBrowse link 12 2,419,456 2,422,832 RGD:13508589
G PSMB9 proteasome 20S subunit beta 9 JBrowse link 12 2,432,287 2,438,920 RGD:13508589
proteasome core complex, alpha-subunit complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G LOC102152879 proteasome subunit alpha type-1-like JBrowse link 30 24,114,023 24,116,951 RGD:13508589
G PSMA1 proteasome 20S subunit alpha 1 JBrowse link 21 37,230,253 37,243,356 RGD:13508589
G PSMA2 proteasome 20S subunit alpha 2 JBrowse link 18 7,218,150 7,228,859 RGD:13508589
G PSMA3 proteasome 20S subunit alpha 3 JBrowse link 8 33,616,735 33,642,434 RGD:13508589
G PSMA4 proteasome 20S subunit alpha 4 JBrowse link X 53,245,249 53,246,357 RGD:13508589
G PSMA5 proteasome 20S subunit alpha 5 JBrowse link 6 42,425,590 42,450,074 RGD:13508589
G PSMA6 proteasome 20S subunit alpha 6 JBrowse link 8 14,010,899 14,038,141 RGD:13508589
G PSMA7 proteasome 20S subunit alpha 7 JBrowse link 24 46,182,344 46,186,241 RGD:13508589
G PSMA8 proteasome 20S subunit alpha 8 JBrowse link 7 62,432,477 62,472,984 RGD:13508589
proteasome core complex, beta-subunit complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PSMB3 proteasome 20S subunit beta 3 JBrowse link 9 23,474,476 23,484,408 RGD:13508589
G PSMB8 proteasome 20S subunit beta 8 JBrowse link 12 2,419,456 2,422,832 RGD:13508589
proteasome regulatory particle term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PRICKLE2 prickle planar cell polarity protein 2 JBrowse link 20 26,810,167 27,131,864 RGD:13508589
G PSMD7 proteasome 26S subunit, non-ATPase 7 JBrowse link 5 79,785,620 79,793,793 RGD:13508589
G PSMD8 proteasome 26S subunit, non-ATPase 8 JBrowse link 1 114,619,478 114,626,082 RGD:13508589
G SPRED3 sprouty related EVH1 domain containing 3 JBrowse link 1 114,604,265 114,614,764 RGD:13508589
proteasome regulatory particle, base subcomplex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G LOC100687259 26S proteasome regulatory subunit 10B JBrowse link 32 35,814,756 35,816,311 RGD:13508589
G PSMC1 proteasome 26S subunit, ATPase 1 JBrowse link 8 61,272,363 61,285,886 RGD:13508589
G PSMC2 proteasome 26S subunit, ATPase 2 JBrowse link 18 16,845,593 16,859,010 RGD:13508589
G PSMC3 proteasome 26S subunit, ATPase 3 JBrowse link 18 42,212,083 42,218,958 RGD:13508589
G PSMC4 proteasome 26S subunit, ATPase 4 JBrowse link 1 113,548,351 113,557,725 RGD:13508589
G PSMC5 proteasome 26S subunit, ATPase 5 JBrowse link 9 11,783,422 11,787,624 RGD:13508589
G PSMC6 proteasome 26S subunit, ATPase 6 JBrowse link 8 28,914,302 28,947,854 RGD:13508589
G PSMD1 proteasome 26S subunit, non-ATPase 1 JBrowse link 25 43,003,127 43,096,281 RGD:13508589
G PSMD10 proteasome 26S subunit, non-ATPase 10 JBrowse link X 81,625,288 81,632,175 RGD:13508589
G PSMD2 proteasome 26S subunit, non-ATPase 2 JBrowse link 34 17,180,119 17,189,298 RGD:13508589
G PSMD4 proteasome 26S subunit, non-ATPase 4 JBrowse link 17 60,306,134 60,313,610 RGD:13508589
G PSMD9 proteasome 26S subunit, non-ATPase 9 JBrowse link 26 7,376,154 7,400,655 RGD:13508589
proteasome regulatory particle, lid subcomplex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ADRM1 adhesion regulating molecule 1 JBrowse link 24 46,309,478 46,314,892 RGD:13508589
G PSMD11 proteasome 26S subunit, non-ATPase 11 JBrowse link 9 40,507,227 40,538,967 RGD:13508589
G PSMD12 proteasome 26S subunit, non-ATPase 12 JBrowse link 9 13,136,883 13,170,544 RGD:13508589
G PSMD13 proteasome 26S subunit, non-ATPase 13 JBrowse link 18 25,388,212 25,401,071 RGD:13508589
G PSMD14 proteasome 26S subunit, non-ATPase 14 JBrowse link 36 6,883,612 6,985,291 RGD:13508589
G PSMD3 proteasome 26S subunit, non-ATPase 3 JBrowse link 9 22,538,368 22,553,221 RGD:13508589
G PSMD8 proteasome 26S subunit, non-ATPase 8 JBrowse link 1 114,619,478 114,626,082 RGD:13508589
proteasome storage granule term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PSMD1 proteasome 26S subunit, non-ATPase 1 JBrowse link 25 43,003,127 43,096,281 RGD:13508589
G PSMD2 proteasome 26S subunit, non-ATPase 2 JBrowse link 34 17,180,119 17,189,298 RGD:13508589
spermatoproteasome complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PSMA8 proteasome 20S subunit alpha 8 JBrowse link 7 62,432,477 62,472,984 RGD:13508589
G PSMB10 proteasome 20S subunit beta 10 JBrowse link 5 81,560,750 81,563,571 RGD:13508589
G PSMB8 proteasome 20S subunit beta 8 JBrowse link 12 2,419,456 2,422,832 RGD:13508589
G PSME4 proteasome activator subunit 4 JBrowse link 10 54,873,093 54,960,030 RGD:13508589

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 14547
    intracellular 10132
      proteasome complex 52
        cytosolic proteasome complex + 6
        nuclear proteasome complex + 3
        proteasome accessory complex + 26
        proteasome core complex + 19
        spermatoproteasome complex 4
Path 2
Term Annotations click to browse term
  cellular_component 14547
    protein-containing complex 4078
      catalytic complex 1126
        peptidase complex 77
          endopeptidase complex 53
            proteasome complex 52
              cytosolic proteasome complex + 6
              nuclear proteasome complex + 3
              proteasome accessory complex + 26
              proteasome core complex + 19
              spermatoproteasome complex 4
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.