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ONTOLOGY REPORT - ANNOTATIONS


Term:proteasome complex
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Accession:GO:0000502 term browser browse the term
Definition:A large multisubunit complex which catalyzes protein degradation, found in eukaryotes, archaea and some bacteria. In eukaryotes, this complex consists of the barrel shaped proteasome core complex and one or two associated proteins or complexes that act in regulating entry into or exit from the core.
Synonyms:exact_synonym: proteasome
 narrow_synonym: 26S proteasome


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proteasome complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ADRM1 adhesion regulating molecule 1 JBrowse link 20 62,302,061 62,308,862 RGD:2290271
G DNAJB2 DnaJ heat shock protein family (Hsp40) member B2 JBrowse link 2 219,279,366 219,286,895 RGD:2290271
G ECPAS Ecm29 proteasome adaptor and scaffold JBrowse link 9 111,360,685 111,484,383 RGD:2290271
G HSPB1 heat shock protein family B (small) member 1 JBrowse link 7 76,302,673 76,304,292 RGD:2290271
G PAAF1 proteasomal ATPase associated factor 1 JBrowse link 11 73,876,699 73,931,114 RGD:2290271
G PSMA1 proteasome 20S subunit alpha 1 JBrowse link 11 14,504,876 14,643,634 RGD:2290271
G PSMA2 proteasome 20S subunit alpha 2 JBrowse link 7 42,916,861 42,932,174 RGD:2290271
G PSMA3 proteasome 20S subunit alpha 3 JBrowse link 14 58,244,805 58,272,009 RGD:2290271
G PSMA4 proteasome 20S subunit alpha 4 JBrowse link 15 78,540,405 78,552,417 RGD:2290271
G PSMA5 proteasome 20S subunit alpha 5 JBrowse link 1 109,399,042 109,426,448 RGD:2290271
G PSMA6 proteasome 20S subunit alpha 6 JBrowse link 14 35,278,558 35,317,493 RGD:2290271
G PSMA7 proteasome 20S subunit alpha 7 JBrowse link 20 62,136,733 62,143,394 RGD:2290271
G PSMB1 proteasome 20S subunit beta 1 JBrowse link 6 170,535,120 170,553,307 RGD:2290271
G PSMB10 proteasome 20S subunit beta 10 JBrowse link 16 67,934,506 67,936,850 RGD:2290271
G PSMB2 proteasome 20S subunit beta 2 JBrowse link 1 35,599,541 35,641,526 RGD:2290271
G PSMB3 proteasome 20S subunit beta 3 JBrowse link 17 38,752,741 38,764,225 RGD:2290271
G PSMB4 proteasome 20S subunit beta 4 JBrowse link 1 151,399,573 151,401,937 RGD:2290271
G PSMB5 proteasome 20S subunit beta 5 JBrowse link 14 23,025,851 23,035,220 RGD:2290271
G PSMB6 proteasome 20S subunit beta 6 JBrowse link 17 4,796,144 4,798,503 RGD:2290271
G PSMB7 proteasome 20S subunit beta 7 JBrowse link 9 124,353,465 124,415,442 RGD:2290271
G PSMB8 proteasome 20S subunit beta 8 JBrowse link 6 32,840,717 32,844,679 RGD:2290271
G PSMB9 proteasome 20S subunit beta 9 JBrowse link 6 32,854,192 32,859,851 RGD:2290271
G PSMC1 proteasome 26S subunit, ATPase 1 JBrowse link 14 90,256,553 90,275,429 RGD:2290271
G PSMC2 proteasome 26S subunit, ATPase 2 JBrowse link 7 103,344,405 103,369,395 RGD:2290271
G PSMC3 proteasome 26S subunit, ATPase 3 JBrowse link 11 47,418,769 47,426,473 RGD:2290271
G PSMC4 proteasome 26S subunit, ATPase 4 JBrowse link 19 39,971,005 39,981,764 RGD:2290271
G PSMC5 proteasome 26S subunit, ATPase 5 JBrowse link 17 63,827,431 63,832,027 RGD:2290271
G PSMC6 proteasome 26S subunit, ATPase 6 JBrowse link 14 52,707,163 52,728,590 RGD:2290271
G PSMD1 proteasome 26S subunit, non-ATPase 1 JBrowse link 2 231,056,864 231,172,827 RGD:2290271
G PSMD10 proteasome 26S subunit, non-ATPase 10 JBrowse link X 108,084,205 108,091,644 RGD:2290271
G PSMD11 proteasome 26S subunit, non-ATPase 11 JBrowse link 17 32,444,510 32,483,319 RGD:2290271
G PSMD12 proteasome 26S subunit, non-ATPase 12 JBrowse link 17 67,337,916 67,366,598 RGD:2290271
G PSMD13 proteasome 26S subunit, non-ATPase 13 JBrowse link 11 236,972 252,984 RGD:2290271
G PSMD14 proteasome 26S subunit, non-ATPase 14 JBrowse link 2 161,308,425 161,411,717 RGD:2290271
G PSMD2 proteasome 26S subunit, non-ATPase 2 JBrowse link 3 184,299,241 184,309,050 RGD:2290271
G PSMD3 proteasome 26S subunit, non-ATPase 3 JBrowse link 17 39,980,807 39,997,959 RGD:2290271
G PSMD4 proteasome 26S subunit, non-ATPase 4 JBrowse link 1 151,254,734 151,267,479 RGD:2290271
G PSMD5 proteasome 26S subunit, non-ATPase 5 JBrowse link 9 120,816,053 120,842,922 RGD:2290271
G PSMD6 proteasome 26S subunit, non-ATPase 6 JBrowse link 3 64,010,549 64,024,010 RGD:2290271
G PSMD7 proteasome 26S subunit, non-ATPase 7 JBrowse link 16 74,296,814 74,306,288 RGD:2290271
G PSMD8 proteasome 26S subunit, non-ATPase 8 JBrowse link 19 38,374,550 38,383,824 RGD:2290271
G PSME1 proteasome activator subunit 1 JBrowse link 14 24,136,158 24,138,967 RGD:2290271
G PSME2 proteasome activator subunit 2 JBrowse link 14 24,143,365 24,146,646 RGD:2290271
G PSME3 proteasome activator subunit 3 JBrowse link 17 42,833,397 42,843,760 RGD:2290271
G RAD23A RAD23 homolog A, nucleotide excision repair protein JBrowse link 19 12,945,814 12,953,643 RGD:2290271
G RAD23B RAD23 homolog B, nucleotide excision repair protein JBrowse link 9 107,283,279 107,332,194 RGD:2290271
G SEM1 SEM1 26S proteasome complex subunit JBrowse link 7 96,481,626 96,709,891 RGD:2290271
G TXNL1 thioredoxin like 1 JBrowse link 18 56,597,209 56,638,635 RGD:2290271
G UBE3A ubiquitin protein ligase E3A JBrowse link 15 25,333,728 25,439,381 RGD:2290271
G UBE3C ubiquitin protein ligase E3C JBrowse link 7 157,138,926 157,269,370 RGD:2290271
G UBQLN1 ubiquilin 1 JBrowse link 9 83,659,968 83,707,979 RGD:2290271
G UBR1 ubiquitin protein ligase E3 component n-recognin 1 JBrowse link 15 42,942,897 43,106,038 RGD:2290271
G UCHL5 ubiquitin C-terminal hydrolase L5 JBrowse link 1 193,012,254 193,060,140 RGD:2290271
G USP14 ubiquitin specific peptidase 14 JBrowse link 18 158,557 214,629 RGD:2290271
G VCP valosin containing protein JBrowse link 9 35,056,064 35,072,668 RGD:2290271
G ZFAND2A zinc finger AN1-type containing 2A JBrowse link 7 1,148,850 1,160,196 RGD:2290271
G ZFAND2B zinc finger AN1-type containing 2B JBrowse link 2 219,206,782 219,209,651 RGD:2290271
cytosolic proteasome complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G IDE insulin degrading enzyme JBrowse link 10 92,451,684 92,574,095 RGD:2290271
G PSMC4 proteasome 26S subunit, ATPase 4 JBrowse link 19 39,971,005 39,981,764 RGD:2290271
G PSMC5 proteasome 26S subunit, ATPase 5 JBrowse link 17 63,827,431 63,832,027 RGD:2290271
G PSMC6 proteasome 26S subunit, ATPase 6 JBrowse link 14 52,707,163 52,728,590 RGD:2290271
G PSMD14 proteasome 26S subunit, non-ATPase 14 JBrowse link 2 161,308,425 161,411,717 RGD:2290271
G UBQLN4 ubiquilin 4 JBrowse link 1 156,033,129 156,053,798 RGD:2290271
G UCHL5 ubiquitin C-terminal hydrolase L5 JBrowse link 1 193,012,254 193,060,140 RGD:2290271
nuclear proteasome complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PSMC5 proteasome 26S subunit, ATPase 5 JBrowse link 17 63,827,431 63,832,027 RGD:2290271
G PSMD12 proteasome 26S subunit, non-ATPase 12 JBrowse link 17 67,337,916 67,366,598 RGD:2290271
G UBQLN4 ubiquilin 4 JBrowse link 1 156,033,129 156,053,798 RGD:2290271
proteasome accessory complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PSMC1 proteasome 26S subunit, ATPase 1 JBrowse link 14 90,256,553 90,275,429 RGD:2290271
G PSMC2 proteasome 26S subunit, ATPase 2 JBrowse link 7 103,344,405 103,369,395 RGD:2290271
G PSMC3 proteasome 26S subunit, ATPase 3 JBrowse link 11 47,418,769 47,426,473 RGD:2290271
G PSMC4 proteasome 26S subunit, ATPase 4 JBrowse link 19 39,971,005 39,981,764 RGD:2290271
G PSMC5 proteasome 26S subunit, ATPase 5 JBrowse link 17 63,827,431 63,832,027 RGD:2290271
G PSMC6 proteasome 26S subunit, ATPase 6 JBrowse link 14 52,707,163 52,728,590 RGD:2290271
G PSMD1 proteasome 26S subunit, non-ATPase 1 JBrowse link 2 231,056,864 231,172,827 RGD:2290271
G PSMD11 proteasome 26S subunit, non-ATPase 11 JBrowse link 17 32,444,510 32,483,319 RGD:2290271
G PSMD12 proteasome 26S subunit, non-ATPase 12 JBrowse link 17 67,337,916 67,366,598 RGD:2290271
G PSMD13 proteasome 26S subunit, non-ATPase 13 JBrowse link 11 236,972 252,984 RGD:2290271
G PSMD14 proteasome 26S subunit, non-ATPase 14 JBrowse link 2 161,308,425 161,411,717 RGD:2290271
G PSMD2 proteasome 26S subunit, non-ATPase 2 JBrowse link 3 184,299,241 184,309,050 RGD:2290271
G PSMD3 proteasome 26S subunit, non-ATPase 3 JBrowse link 17 39,980,807 39,997,959 RGD:2290271
G PSMD4 proteasome 26S subunit, non-ATPase 4 JBrowse link 1 151,254,734 151,267,479 RGD:2290271
G PSMD5 proteasome 26S subunit, non-ATPase 5 JBrowse link 9 120,816,053 120,842,922 RGD:2290271
G PSMD6 proteasome 26S subunit, non-ATPase 6 JBrowse link 3 64,010,549 64,024,010 RGD:2290271
G PSMD8 proteasome 26S subunit, non-ATPase 8 JBrowse link 19 38,374,550 38,383,824 RGD:2290271
proteasome activator complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PSME1 proteasome activator subunit 1 JBrowse link 14 24,136,158 24,138,967 RGD:2290271
G PSME2 proteasome activator subunit 2 JBrowse link 14 24,143,365 24,146,646 RGD:2290271
G PSME3 proteasome activator subunit 3 JBrowse link 17 42,833,397 42,843,760 RGD:2290271
proteasome core complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AC018523.2 novel protein RGD:2290271
G AC040162.1 novel transcript RGD:2290271
G PSMA1 proteasome 20S subunit alpha 1 JBrowse link 11 14,504,876 14,643,634 RGD:2290271
G PSMA2 proteasome 20S subunit alpha 2 JBrowse link 7 42,916,861 42,932,174 RGD:2290271
G PSMA3 proteasome 20S subunit alpha 3 JBrowse link 14 58,244,805 58,272,009 RGD:2290271
G PSMA4 proteasome 20S subunit alpha 4 JBrowse link 15 78,540,405 78,552,417 RGD:2290271
G PSMA5 proteasome 20S subunit alpha 5 JBrowse link 1 109,399,042 109,426,448 RGD:2290271
G PSMA6 proteasome 20S subunit alpha 6 JBrowse link 14 35,278,558 35,317,493 RGD:2290271
G PSMA7 proteasome 20S subunit alpha 7 JBrowse link 20 62,136,733 62,143,394 RGD:2290271
G PSMA8 proteasome 20S subunit alpha 8 JBrowse link 18 26,133,869 26,193,355 RGD:2290271
G PSMB1 proteasome 20S subunit beta 1 JBrowse link 6 170,535,120 170,553,307 RGD:2290271
G PSMB10 proteasome 20S subunit beta 10 JBrowse link 16 67,934,506 67,936,850 RGD:2290271
G PSMB11 proteasome subunit beta 11 JBrowse link 14 23,042,212 23,044,060 RGD:2290271
G PSMB2 proteasome 20S subunit beta 2 JBrowse link 1 35,599,541 35,641,526 RGD:2290271
G PSMB3 proteasome 20S subunit beta 3 JBrowse link 17 38,752,741 38,764,225 RGD:2290271
G PSMB4 proteasome 20S subunit beta 4 JBrowse link 1 151,399,573 151,401,937 RGD:2290271
G PSMB5 proteasome 20S subunit beta 5 JBrowse link 14 23,025,851 23,035,220 RGD:2290271
G PSMB6 proteasome 20S subunit beta 6 JBrowse link 17 4,796,144 4,798,503 RGD:2290271
G PSMB7 proteasome 20S subunit beta 7 JBrowse link 9 124,353,465 124,415,442 RGD:2290271
G PSMB8 proteasome 20S subunit beta 8 JBrowse link 6 32,840,717 32,844,679 RGD:2290271
G PSMB9 proteasome 20S subunit beta 9 JBrowse link 6 32,854,192 32,859,851 RGD:2290271
G PSMF1 proteasome inhibitor subunit 1 JBrowse link 20 1,113,229 1,172,246 RGD:2290271
proteasome core complex, alpha-subunit complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AC018523.2 novel protein RGD:2290271
G PSMA1 proteasome 20S subunit alpha 1 JBrowse link 11 14,504,876 14,643,634 RGD:2290271
G PSMA2 proteasome 20S subunit alpha 2 JBrowse link 7 42,916,861 42,932,174 RGD:2290271
G PSMA3 proteasome 20S subunit alpha 3 JBrowse link 14 58,244,805 58,272,009 RGD:2290271
G PSMA4 proteasome 20S subunit alpha 4 JBrowse link 15 78,540,405 78,552,417 RGD:2290271
G PSMA5 proteasome 20S subunit alpha 5 JBrowse link 1 109,399,042 109,426,448 RGD:2290271
G PSMA6 proteasome 20S subunit alpha 6 JBrowse link 14 35,278,558 35,317,493 RGD:2290271
G PSMA7 proteasome 20S subunit alpha 7 JBrowse link 20 62,136,733 62,143,394 RGD:2290271
G PSMA8 proteasome 20S subunit alpha 8 JBrowse link 18 26,133,869 26,193,355 RGD:2290271
proteasome core complex, beta-subunit complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PSMB1 proteasome 20S subunit beta 1 JBrowse link 6 170,535,120 170,553,307 RGD:2290271
G PSMB10 proteasome 20S subunit beta 10 JBrowse link 16 67,934,506 67,936,850 RGD:2290271
G PSMB11 proteasome subunit beta 11 JBrowse link 14 23,042,212 23,044,060 RGD:2290271
G PSMB2 proteasome 20S subunit beta 2 JBrowse link 1 35,599,541 35,641,526 RGD:2290271
G PSMB3 proteasome 20S subunit beta 3 JBrowse link 17 38,752,741 38,764,225 RGD:2290271
G PSMB4 proteasome 20S subunit beta 4 JBrowse link 1 151,399,573 151,401,937 RGD:2290271
G PSMB5 proteasome 20S subunit beta 5 JBrowse link 14 23,025,851 23,035,220 RGD:2290271
G PSMB6 proteasome 20S subunit beta 6 JBrowse link 17 4,796,144 4,798,503 RGD:2290271
G PSMB7 proteasome 20S subunit beta 7 JBrowse link 9 124,353,465 124,415,442 RGD:2290271
G PSMB8 proteasome 20S subunit beta 8 JBrowse link 6 32,840,717 32,844,679 RGD:2290271
G PSMB9 proteasome 20S subunit beta 9 JBrowse link 6 32,854,192 32,859,851 RGD:2290271
proteasome regulatory particle term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PSMD1 proteasome 26S subunit, non-ATPase 1 JBrowse link 2 231,056,864 231,172,827 RGD:2290271
G PSMD12 proteasome 26S subunit, non-ATPase 12 JBrowse link 17 67,337,916 67,366,598 RGD:2290271
G PSMD13 proteasome 26S subunit, non-ATPase 13 JBrowse link 11 236,972 252,984 RGD:2290271
G PSMD2 proteasome 26S subunit, non-ATPase 2 JBrowse link 3 184,299,241 184,309,050 RGD:2290271
G PSMD6 proteasome 26S subunit, non-ATPase 6 JBrowse link 3 64,010,549 64,024,010 RGD:2290271
G PSMD7 proteasome 26S subunit, non-ATPase 7 JBrowse link 16 74,296,814 74,306,288 RGD:2290271
G PSMD8 proteasome 26S subunit, non-ATPase 8 JBrowse link 19 38,374,550 38,383,824 RGD:2290271
G PSMD9 proteasome 26S subunit, non-ATPase 9 JBrowse link 12 121,888,790 121,918,297 RGD:2290271
proteasome regulatory particle, base subcomplex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PSMC1 proteasome 26S subunit, ATPase 1 JBrowse link 14 90,256,553 90,275,429 RGD:2290271
G PSMC2 proteasome 26S subunit, ATPase 2 JBrowse link 7 103,344,405 103,369,395 RGD:2290271
G PSMC3 proteasome 26S subunit, ATPase 3 JBrowse link 11 47,418,769 47,426,473 RGD:2290271
G PSMC4 proteasome 26S subunit, ATPase 4 JBrowse link 19 39,971,005 39,981,764 RGD:2290271
G PSMC5 proteasome 26S subunit, ATPase 5 JBrowse link 17 63,827,431 63,832,027 RGD:2290271
G PSMC6 proteasome 26S subunit, ATPase 6 JBrowse link 14 52,707,163 52,728,590 RGD:2290271
G PSMD1 proteasome 26S subunit, non-ATPase 1 JBrowse link 2 231,056,864 231,172,827 RGD:2290271
G PSMD10 proteasome 26S subunit, non-ATPase 10 JBrowse link X 108,084,205 108,091,644 RGD:2290271
G PSMD2 proteasome 26S subunit, non-ATPase 2 JBrowse link 3 184,299,241 184,309,050 RGD:2290271
G PSMD4 proteasome 26S subunit, non-ATPase 4 JBrowse link 1 151,254,734 151,267,479 RGD:2290271
G PSMD5 proteasome 26S subunit, non-ATPase 5 JBrowse link 9 120,816,053 120,842,922 RGD:2290271
G PSMD9 proteasome 26S subunit, non-ATPase 9 JBrowse link 12 121,888,790 121,918,297 RGD:2290271
proteasome regulatory particle, lid subcomplex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ADRM1 adhesion regulating molecule 1 JBrowse link 20 62,302,061 62,308,862 RGD:2290271
G PSMD11 proteasome 26S subunit, non-ATPase 11 JBrowse link 17 32,444,510 32,483,319 RGD:2290271
G PSMD12 proteasome 26S subunit, non-ATPase 12 JBrowse link 17 67,337,916 67,366,598 RGD:2290271
G PSMD13 proteasome 26S subunit, non-ATPase 13 JBrowse link 11 236,972 252,984 RGD:2290271
G PSMD14 proteasome 26S subunit, non-ATPase 14 JBrowse link 2 161,308,425 161,411,717 RGD:2290271
G PSMD3 proteasome 26S subunit, non-ATPase 3 JBrowse link 17 39,980,807 39,997,959 RGD:2290271
G PSMD8 proteasome 26S subunit, non-ATPase 8 JBrowse link 19 38,374,550 38,383,824 RGD:2290271
G SEM1 SEM1 26S proteasome complex subunit JBrowse link 7 96,481,626 96,709,891 RGD:2290271
proteasome storage granule term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PSMD1 proteasome 26S subunit, non-ATPase 1 JBrowse link 2 231,056,864 231,172,827 RGD:2290271
G PSMD2 proteasome 26S subunit, non-ATPase 2 JBrowse link 3 184,299,241 184,309,050 RGD:2290271
spermatoproteasome complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PSMA8 proteasome 20S subunit alpha 8 JBrowse link 18 26,133,869 26,193,355 RGD:2290271
G PSMB10 proteasome 20S subunit beta 10 JBrowse link 16 67,934,506 67,936,850 RGD:2290271
G PSMB8 proteasome 20S subunit beta 8 JBrowse link 6 32,840,717 32,844,679 RGD:2290271
G PSMB9 proteasome 20S subunit beta 9 JBrowse link 6 32,854,192 32,859,851 RGD:2290271
G PSME4 proteasome activator subunit 4 JBrowse link 2 53,864,069 53,970,993 RGD:2290271

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 19032
    intracellular 14666
      proteasome complex 66
        cytosolic proteasome complex + 9
        nuclear proteasome complex + 3
        proteasome accessory complex + 25
        proteasome core complex + 22
        spermatoproteasome complex 5
Path 2
Term Annotations click to browse term
  cellular_component 19032
    protein-containing complex 5621
      catalytic complex 1406
        peptidase complex 93
          endopeptidase complex 67
            proteasome complex 66
              cytosolic proteasome complex + 9
              nuclear proteasome complex + 3
              proteasome accessory complex + 25
              proteasome core complex + 22
              spermatoproteasome complex 5
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.