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ONTOLOGY REPORT - ANNOTATIONS


Term:proteasome complex
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Accession:GO:0000502 term browser browse the term
Definition:A large multisubunit complex which catalyzes protein degradation, found in eukaryotes, archaea and some bacteria. In eukaryotes, this complex consists of the barrel shaped proteasome core complex and one or two associated proteins or complexes that act in regulating entry into or exit from the core.
Synonyms:exact_synonym: proteasome
 narrow_synonym: 26S proteasome


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proteasome complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adrm1 adhesion regulating molecule 1 JBrowse link 2 180,171,226 180,176,286 RGD:2290270
G Dnajb2 DnaJ heat shock protein family (Hsp40) member B2 JBrowse link 1 75,236,395 75,245,692 RGD:2290270
G Ecpas Ecm29 proteasome adaptor and scaffold JBrowse link 4 58,797,234 58,917,748 RGD:2290270
G Hspb1 heat shock protein 1 JBrowse link 5 135,887,919 135,889,563 RGD:2290270
G Psma1 proteasome subunit alpha 1 JBrowse link 7 114,264,550 114,276,116 RGD:2290270
G Psma2 proteasome subunit alpha 2 JBrowse link 13 14,613,242 14,625,673 RGD:2290270
G Psma3 proteasome subunit alpha 3 JBrowse link 12 70,969,283 70,995,877 RGD:2290270
G Psma4 proteasome subunit alpha 4 JBrowse link 9 54,950,781 54,958,034 RGD:2290270
G Psma5 proteasome subunit alpha 5 JBrowse link 3 108,256,926 108,279,952 RGD:2290270
G Psma6 proteasome subunit alpha 6 JBrowse link 12 55,384,222 55,418,459 RGD:2290270
G Psma7 proteasome subunit alpha 7 JBrowse link 2 180,036,367 180,042,464 RGD:2290270
G Psma8 proteasome subunit alpha 8 JBrowse link 18 14,706,135 14,762,301 RGD:2290270
G Psmb1 proteasome (prosome, macropain) subunit, beta type 1 JBrowse link 17 15,475,721 15,498,276 RGD:2290270
G Psmb10 proteasome (prosome, macropain) subunit, beta type 10 JBrowse link 8 105,935,728 105,938,392 RGD:2290270
G Psmb11 proteasome (prosome, macropain) subunit, beta type, 11 JBrowse link 14 54,625,310 54,629,556 RGD:2290270
G Psmb2 proteasome (prosome, macropain) subunit, beta type 2 JBrowse link 4 126,677,637 126,709,715 RGD:2290270
G Psmb3 proteasome (prosome, macropain) subunit, beta type 3 JBrowse link 11 97,703,434 97,713,500 RGD:2290270
G Psmb4 proteasome (prosome, macropain) subunit, beta type 4 JBrowse link 3 94,884,324 94,886,958 RGD:2290270
G Psmb5 proteasome (prosome, macropain) subunit, beta type 5 JBrowse link 14 54,614,120 54,617,995 RGD:2290270
G Psmb6 proteasome (prosome, macropain) subunit, beta type 6 JBrowse link 11 70,525,324 70,527,858 RGD:2290270
G Psmb7 proteasome (prosome, macropain) subunit, beta type 7 JBrowse link 2 38,588,046 38,643,952 RGD:2290270
G Psmb8 proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7) JBrowse link 17 34,198,195 34,201,454 RGD:2290270
G Psmb9 proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2) JBrowse link 17 34,182,030 34,187,330 RGD:2290270
G Psmc1 protease (prosome, macropain) 26S subunit, ATPase 1 JBrowse link 12 100,110,202 100,123,364 RGD:2290270
G Psmc2 proteasome (prosome, macropain) 26S subunit, ATPase 2 JBrowse link 5 21,785,275 21,803,787 RGD:2290270
G Psmc3 proteasome (prosome, macropain) 26S subunit, ATPase 3 JBrowse link 2 91,054,016 91,059,438 RGD:2290270
G Psmc4 proteasome (prosome, macropain) 26S subunit, ATPase, 4 JBrowse link 7 28,041,702 28,050,092 RGD:2290270
G Psmc5 protease (prosome, macropain) 26S subunit, ATPase 5 JBrowse link 11 106,256,185 106,263,112 RGD:2290270
G Psmc6 proteasome (prosome, macropain) 26S subunit, ATPase, 6 JBrowse link 14 45,329,823 45,349,074 RGD:2290270
G Psmd1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 JBrowse link 1 86,064,619 86,139,295 RGD:2290270
G Psmd10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 JBrowse link X 140,948,425 140,956,711 RGD:2290270
G Psmd11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 JBrowse link 11 80,428,615 80,473,248 RGD:2290270
G Psmd12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 JBrowse link 11 107,479,528 107,498,036 RGD:2290270
G Psmd13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 JBrowse link 7 140,882,394 140,898,642 RGD:2290270
G Psmd14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 JBrowse link 2 61,711,694 61,800,376 RGD:2290270
G Psmd2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 JBrowse link 16 20,651,122 20,663,414 RGD:2290270
G Psmd3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 JBrowse link 11 98,682,554 98,695,978 RGD:2290270
G Psmd4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 JBrowse link 3 95,032,688 95,042,614 RGD:2290270
G Psmd6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 JBrowse link 14 14,112,185 14,120,945 RGD:2290270
G Psmd7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 JBrowse link 8 107,580,380 107,588,482 RGD:2290270
G Psmd8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 JBrowse link 7 29,174,187 29,180,673 RGD:2290270
G Psme1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) JBrowse link 14 55,578,494 55,581,527 RGD:2290270
G Psme3 proteaseome (prosome, macropain) activator subunit 3 (PA28 gamma, Ki) JBrowse link 11 101,316,213 101,323,537 RGD:2290270
G Psme4 proteasome (prosome, macropain) activator subunit 4 JBrowse link 11 30,771,775 30,881,150 RGD:2290270
G Psmf1 proteasome (prosome, macropain) inhibitor subunit 1 JBrowse link 2 151,716,062 151,744,199 RGD:2290270
G Rad23a RAD23 homolog A, nucleotide excision repair protein JBrowse link 8 84,834,652 84,840,736 RGD:2290270
G Rad23b RAD23 homolog B, nucleotide excision repair protein JBrowse link 4 55,350,042 55,392,237 RGD:2290270
G Sem1 SEM1, 26S proteasome complex subunit JBrowse link 6 6,558,275 6,578,658 RGD:2290270
G Slc10a2 solute carrier family 10, member 2 JBrowse link 8 5,083,219 5,105,287 RGD:2290270
G Txnl1 thioredoxin-like 1 JBrowse link 18 63,662,801 63,692,359 RGD:2290270
G Ube3a ubiquitin protein ligase E3A JBrowse link 7 59,228,750 59,310,837 RGD:2290270
G Ubqln1 ubiquilin 1 JBrowse link 13 58,176,156 58,215,653 RGD:2290270
G Ubr1 ubiquitin protein ligase E3 component n-recognin 1 JBrowse link 2 120,860,272 120,970,760 RGD:2290270
G Uchl5 ubiquitin carboxyl-terminal esterase L5 JBrowse link 1 143,777,234 143,807,466 RGD:2290270
G Usp14 ubiquitin specific peptidase 14 JBrowse link 18 9,993,615 10,030,149 RGD:2290270
G Usp25 ubiquitin specific peptidase 25 JBrowse link 16 77,013,684 77,116,783 RGD:2290270
G Vcp valosin containing protein JBrowse link 4 42,979,964 43,000,507 RGD:2290270
G Zfand2a zinc finger, AN1-type domain 2A JBrowse link 5 139,471,216 139,484,491 RGD:2290270
G Zfand2b zinc finger, AN1 type domain 2B JBrowse link 1 75,168,646 75,171,626 RGD:2290270
cytosolic proteasome complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ide insulin degrading enzyme JBrowse link 19 37,268,741 37,334,544 RGD:2290270
G Psmc4 proteasome (prosome, macropain) 26S subunit, ATPase, 4 JBrowse link 7 28,041,702 28,050,092 RGD:2290270
G Psmc5 protease (prosome, macropain) 26S subunit, ATPase 5 JBrowse link 11 106,256,185 106,263,112 RGD:2290270
G Psmc6 proteasome (prosome, macropain) 26S subunit, ATPase, 6 JBrowse link 14 45,329,823 45,349,074 RGD:2290270
G Psmd14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 JBrowse link 2 61,711,694 61,800,376 RGD:2290270
G Ubqln4 ubiquilin 4 JBrowse link 3 88,553,677 88,569,725 RGD:2290270
G Uchl5 ubiquitin carboxyl-terminal esterase L5 JBrowse link 1 143,777,234 143,807,466 RGD:2290270
nuclear proteasome complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Psmc5 protease (prosome, macropain) 26S subunit, ATPase 5 JBrowse link 11 106,256,185 106,263,112 RGD:2290270
G Psmd12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 JBrowse link 11 107,479,528 107,498,036 RGD:2290270
G Ubqln4 ubiquilin 4 JBrowse link 3 88,553,677 88,569,725 RGD:2290270
proteasome accessory complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Psmc1 protease (prosome, macropain) 26S subunit, ATPase 1 JBrowse link 12 100,110,202 100,123,364 RGD:2290270
G Psmc2 proteasome (prosome, macropain) 26S subunit, ATPase 2 JBrowse link 5 21,785,275 21,803,787 RGD:2290270
G Psmc3 proteasome (prosome, macropain) 26S subunit, ATPase 3 JBrowse link 2 91,054,016 91,059,438 RGD:2290270
G Psmc4 proteasome (prosome, macropain) 26S subunit, ATPase, 4 JBrowse link 7 28,041,702 28,050,092 RGD:2290270
G Psmc5 protease (prosome, macropain) 26S subunit, ATPase 5 JBrowse link 11 106,256,185 106,263,112 RGD:2290270
G Psmc6 proteasome (prosome, macropain) 26S subunit, ATPase, 6 JBrowse link 14 45,329,823 45,349,074 RGD:2290270
G Psmd1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 JBrowse link 1 86,064,619 86,139,295 RGD:2290270
G Psmd11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 JBrowse link 11 80,428,615 80,473,248 RGD:2290270
G Psmd12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 JBrowse link 11 107,479,528 107,498,036 RGD:2290270
G Psmd13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 JBrowse link 7 140,882,394 140,898,642 RGD:2290270
G Psmd14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 JBrowse link 2 61,711,694 61,800,376 RGD:2290270
G Psmd2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 JBrowse link 16 20,651,122 20,663,414 RGD:2290270
G Psmd3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 JBrowse link 11 98,682,554 98,695,978 RGD:2290270
G Psmd4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 JBrowse link 3 95,032,688 95,042,614 RGD:2290270
G Psmd5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 JBrowse link 2 34,852,087 34,870,965 RGD:2290270
G Psmd6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 JBrowse link 14 14,112,185 14,120,945 RGD:2290270
G Psmd8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 JBrowse link 7 29,174,187 29,180,673 RGD:2290270
proteasome activator complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Psme1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) JBrowse link 14 55,578,494 55,581,527 RGD:2290270
G Psme3 proteaseome (prosome, macropain) activator subunit 3 (PA28 gamma, Ki) JBrowse link 11 101,316,213 101,323,537 RGD:2290270
proteasome core complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Psma1 proteasome subunit alpha 1 JBrowse link 7 114,264,550 114,276,116 RGD:2290270
G Psma2 proteasome subunit alpha 2 JBrowse link 13 14,613,242 14,625,673 RGD:2290270
G Psma3 proteasome subunit alpha 3 JBrowse link 12 70,969,283 70,995,877 RGD:2290270
G Psma4 proteasome subunit alpha 4 JBrowse link 9 54,950,781 54,958,034 RGD:2290270
G Psma5 proteasome subunit alpha 5 JBrowse link 3 108,256,926 108,279,952 RGD:2290270
G Psma6 proteasome subunit alpha 6 JBrowse link 12 55,384,222 55,418,459 RGD:2290270
G Psma7 proteasome subunit alpha 7 JBrowse link 2 180,036,367 180,042,464 RGD:2290270
G Psma8 proteasome subunit alpha 8 JBrowse link 18 14,706,135 14,762,301 RGD:2290270
G Psmb1 proteasome (prosome, macropain) subunit, beta type 1 JBrowse link 17 15,475,721 15,498,276 RGD:2290270
G Psmb10 proteasome (prosome, macropain) subunit, beta type 10 JBrowse link 8 105,935,728 105,938,392 RGD:2290270
G Psmb11 proteasome (prosome, macropain) subunit, beta type, 11 JBrowse link 14 54,625,310 54,629,556 RGD:2290270
G Psmb2 proteasome (prosome, macropain) subunit, beta type 2 JBrowse link 4 126,677,637 126,709,715 RGD:2290270
G Psmb3 proteasome (prosome, macropain) subunit, beta type 3 JBrowse link 11 97,703,434 97,713,500 RGD:2290270
G Psmb4 proteasome (prosome, macropain) subunit, beta type 4 JBrowse link 3 94,884,324 94,886,958 RGD:2290270
G Psmb5 proteasome (prosome, macropain) subunit, beta type 5 JBrowse link 14 54,614,120 54,617,995 RGD:2290270
G Psmb6 proteasome (prosome, macropain) subunit, beta type 6 JBrowse link 11 70,525,324 70,527,858 RGD:2290270
G Psmb7 proteasome (prosome, macropain) subunit, beta type 7 JBrowse link 2 38,588,046 38,643,952 RGD:2290270
G Psmb8 proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7) JBrowse link 17 34,198,195 34,201,454 RGD:2290270
G Psmb9 proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2) JBrowse link 17 34,182,030 34,187,330 RGD:2290270
proteasome core complex, alpha-subunit complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Psma1 proteasome subunit alpha 1 JBrowse link 7 114,264,550 114,276,116 RGD:2290270
G Psma2 proteasome subunit alpha 2 JBrowse link 13 14,613,242 14,625,673 RGD:2290270
G Psma3 proteasome subunit alpha 3 JBrowse link 12 70,969,283 70,995,877 RGD:2290270
G Psma4 proteasome subunit alpha 4 JBrowse link 9 54,950,781 54,958,034 RGD:2290270
G Psma5 proteasome subunit alpha 5 JBrowse link 3 108,256,926 108,279,952 RGD:2290270
G Psma6 proteasome subunit alpha 6 JBrowse link 12 55,384,222 55,418,459 RGD:2290270
G Psma7 proteasome subunit alpha 7 JBrowse link 2 180,036,367 180,042,464 RGD:2290270
G Psma8 proteasome subunit alpha 8 JBrowse link 18 14,706,135 14,762,301 RGD:2290270
proteasome core complex, beta-subunit complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Psmb3 proteasome (prosome, macropain) subunit, beta type 3 JBrowse link 11 97,703,434 97,713,500 RGD:2290270
proteasome regulatory particle term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Psmc1 protease (prosome, macropain) 26S subunit, ATPase 1 JBrowse link 12 100,110,202 100,123,364 RGD:2290270
G Psmc5 protease (prosome, macropain) 26S subunit, ATPase 5 JBrowse link 11 106,256,185 106,263,112 RGD:2290270
G Psmd11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 JBrowse link 11 80,428,615 80,473,248 RGD:2290270
G Psmd12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 JBrowse link 11 107,479,528 107,498,036 RGD:2290270
G Psmd13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 JBrowse link 7 140,882,394 140,898,642 RGD:2290270
G Psmd2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 JBrowse link 16 20,651,122 20,663,414 RGD:2290270
G Psmd3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 JBrowse link 11 98,682,554 98,695,978 RGD:2290270
G Psmd6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 JBrowse link 14 14,112,185 14,120,945 RGD:2290270
G Psmd7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 JBrowse link 8 107,580,380 107,588,482 RGD:2290270
G Psmd8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 JBrowse link 7 29,174,187 29,180,673 RGD:2290270
proteasome regulatory particle, base subcomplex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Psmc1 protease (prosome, macropain) 26S subunit, ATPase 1 JBrowse link 12 100,110,202 100,123,364 RGD:2290270
G Psmc2 proteasome (prosome, macropain) 26S subunit, ATPase 2 JBrowse link 5 21,785,275 21,803,787 RGD:2290270
G Psmc3 proteasome (prosome, macropain) 26S subunit, ATPase 3 JBrowse link 2 91,054,016 91,059,438 RGD:2290270
G Psmc4 proteasome (prosome, macropain) 26S subunit, ATPase, 4 JBrowse link 7 28,041,702 28,050,092 RGD:2290270
G Psmc5 protease (prosome, macropain) 26S subunit, ATPase 5 JBrowse link 11 106,256,185 106,263,112 RGD:2290270
G Psmc6 proteasome (prosome, macropain) 26S subunit, ATPase, 6 JBrowse link 14 45,329,823 45,349,074 RGD:2290270
G Psmd1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 JBrowse link 1 86,064,619 86,139,295 RGD:2290270
G Psmd10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 JBrowse link X 140,948,425 140,956,711 RGD:2290270
G Psmd2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 JBrowse link 16 20,651,122 20,663,414 RGD:2290270
G Psmd4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 JBrowse link 3 95,032,688 95,042,614 RGD:2290270
G Psmd5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 JBrowse link 2 34,852,087 34,870,965 RGD:2290270
G Psmd9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 JBrowse link 5 123,228,190 123,250,126 RGD:2290270
proteasome regulatory particle, lid subcomplex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adrm1 adhesion regulating molecule 1 JBrowse link 2 180,171,226 180,176,286 RGD:2290270
G Gm9774 predicted pseudogene 9774 JBrowse link 3 92,428,067 92,429,423 RGD:2290270
G Psmd11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 JBrowse link 11 80,428,615 80,473,248 RGD:2290270
G Psmd12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 JBrowse link 11 107,479,528 107,498,036 RGD:2290270
G Psmd13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 JBrowse link 7 140,882,394 140,898,642 RGD:2290270
G Psmd14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 JBrowse link 2 61,711,694 61,800,376 RGD:2290270
G Psmd3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 JBrowse link 11 98,682,554 98,695,978 RGD:2290270
G Psmd8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 JBrowse link 7 29,174,187 29,180,673 RGD:2290270
G Sem1 SEM1, 26S proteasome complex subunit JBrowse link 6 6,558,275 6,578,658 RGD:2290270
proteasome storage granule term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Psmd1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 JBrowse link 1 86,064,619 86,139,295 RGD:2290270
G Psmd2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 JBrowse link 16 20,651,122 20,663,414 RGD:2290270
spermatoproteasome complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Psma8 proteasome subunit alpha 8 JBrowse link 18 14,706,135 14,762,301 RGD:2290270
G Psmb10 proteasome (prosome, macropain) subunit, beta type 10 JBrowse link 8 105,935,728 105,938,392 RGD:2290270
G Psmb8 proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7) JBrowse link 17 34,198,195 34,201,454 RGD:2290270
G Psmb9 proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2) JBrowse link 17 34,182,030 34,187,330 RGD:2290270
G Psme4 proteasome (prosome, macropain) activator subunit 4 JBrowse link 11 30,771,775 30,881,150 RGD:2290270

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 23054
    intracellular 13771
      proteasome complex 64
        cytosolic proteasome complex + 9
        nuclear proteasome complex + 3
        proteasome accessory complex + 25
        proteasome core complex + 19
        spermatoproteasome complex 5
Path 2
Term Annotations click to browse term
  cellular_component 23054
    protein-containing complex 5400
      catalytic complex 1341
        peptidase complex 91
          endopeptidase complex 65
            proteasome complex 64
              cytosolic proteasome complex + 9
              nuclear proteasome complex + 3
              proteasome accessory complex + 25
              proteasome core complex + 19
              spermatoproteasome complex 5
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.