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ONTOLOGY REPORT - ANNOTATIONS


Term:telomere maintenance
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Accession:GO:0000723 term browser browse the term
Definition:Any process that contributes to the maintenance of proper telomeric length and structure by affecting and monitoring the activity of telomeric proteins, the length of telomeric DNA and the replication and repair of the DNA. These processes includes those that shorten, lengthen, replicate and repair the telomeric DNA sequences.
Synonyms:related_synonym: regulation of telomere length


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telomere maintenance term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acd ACD, shelterin complex subunit and telomerase recruitment factor JBrowse link 19 37,665,289 37,668,043 RGD:1624291
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 JBrowse link 15 27,849,943 27,852,083 RGD:1624291
G Atm ATM serine/threonine kinase JBrowse link 8 58,015,938 58,119,973 RGD:13792537
G Atr ATR serine/threonine kinase JBrowse link 8 103,673,578 103,770,886 RGD:13792537
G Blm BLM RecQ like helicase JBrowse link 1 142,246,773 142,332,616 RGD:1624291
RGD:13792537
G Ccne1 cyclin E1 JBrowse link 1 94,485,830 94,495,112 RGD:1624291
RGD:1600115
G Ccne2 cyclin E2 JBrowse link 5 24,434,077 24,446,406 RGD:1624291
G Ctc1 CST telomere replication complex component 1 JBrowse link 10 55,596,172 55,616,873 RGD:1624291
G Dclre1b DNA cross-link repair 1B JBrowse link 2 206,285,085 206,293,599 RGD:1624291
RGD:1600115
G Dclre1c DNA cross-link repair 1C JBrowse link 17 78,782,512 78,812,140 RGD:1624291
G Ercc4 ERCC excision repair 4, endonuclease catalytic subunit JBrowse link 10 2,010,140 2,037,953 RGD:1624291
G Fbxo4 F-box protein 4 JBrowse link 2 53,797,954 53,811,134 RGD:1624291
G Hspa1a heat shock protein family A (Hsp70) member 1A JBrowse link 20 4,875,834 4,881,751 RGD:1624291
G Hus1 HUS1 checkpoint clamp component JBrowse link 14 89,194,086 89,208,825 RGD:13792537
G LOC100910717 tankyrase-2-like JBrowse link 1 255,478,794 255,532,143 RGD:1624291
G Lto1 LTO1 maturation factor of ABCE1 JBrowse link 1 218,075,995 218,082,700 RGD:13792537
G Mre11 MRE11 homolog, double strand break repair nuclease JBrowse link 8 13,304,355 13,350,329 RGD:13792537
G Nbn nibrin JBrowse link 5 29,622,347 29,656,877 RGD:1624291
RGD:1600115
G Parp1 poly (ADP-ribose) polymerase 1 JBrowse link 13 98,857,255 98,889,444 RGD:1624291
G Parp3 poly (ADP-ribose) polymerase family, member 3 JBrowse link 8 115,173,440 115,179,543 RGD:1624291
G Pif1 PIF1 5'-to-3' DNA helicase JBrowse link 8 71,124,477 71,133,460 RGD:1600115
G Prkdc protein kinase, DNA-activated, catalytic subunit JBrowse link 11 89,293,547 89,510,948 RGD:1624291
RGD:13792537
G Rad50 RAD50 double strand break repair protein JBrowse link 10 39,002,130 39,054,042 RGD:68816
RGD:1600115
G Rad51d RAD51 paralog D JBrowse link 10 70,222,703 70,241,352 RGD:1624291
RGD:13792537
G Recql4 RecQ like helicase 4 JBrowse link 7 117,765,892 117,773,128 RGD:1624291
RGD:13792537
G Rif1 replication timing regulatory factor 1 JBrowse link 3 37,599,540 37,648,818 RGD:1624291
RGD:13792537
G Rpa1 replication protein A1 JBrowse link 10 62,140,419 62,191,518 RGD:1624291
RGD:13792537
G Rpa2 replication protein A2 JBrowse link 5 150,957,041 150,967,597 RGD:1624291
RGD:1600115
G Rtel1 regulator of telomere elongation helicase 1 JBrowse link 3 176,818,012 176,856,531 RGD:1624291
RGD:1600115
G Sp100 SP100 nuclear antigen JBrowse link 9 92,675,103 92,718,489 RGD:1624291
G Stn1 STN1 subunit of CST complex JBrowse link 1 267,281,786 267,315,714 RGD:1624291
RGD:1600115
G Terc telomerase RNA component JBrowse link 2 116,432,723 116,433,110 RGD:1624291
G Terf1 telomeric repeat binding factor 1 JBrowse link 5 2,853,455 2,882,731 RGD:1624291
G Terf2 telomeric repeat binding factor 2 JBrowse link 19 39,271,992 39,301,506 RGD:1624291
G Terf2ip TERF2 interacting protein JBrowse link 19 44,231,317 44,238,406 RGD:1624291
RGD:13792537
G Tnks2 tankyrase 2 RGD:1624291
G Wrn WRN RecQ like helicase JBrowse link 16 62,483,773 62,619,018 RGD:1624291
RGD:13792537
G Xrcc5 X-ray repair cross complementing 5 JBrowse link 9 79,659,275 79,748,050 RGD:13792537
G Xrcc6 X-ray repair cross complementing 6 JBrowse link 7 123,259,881 123,280,613 RGD:13792537
G Zfp365 zinc finger protein 365 JBrowse link 20 22,060,160 22,083,766 RGD:1624291
RGD:1600115
mitotic telomere maintenance via semi-conservative replication term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pcna proliferating cell nuclear antigen JBrowse link 3 124,880,698 124,884,570 RGD:1624291
G Rtel1 regulator of telomere elongation helicase 1 JBrowse link 3 176,818,012 176,856,531 RGD:1624291
negative regulation of protection from non-homologous end joining at telomere term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit JBrowse link 1 80,256,973 80,268,198 RGD:1624291
G Ercc4 ERCC excision repair 4, endonuclease catalytic subunit JBrowse link 10 2,010,140 2,037,953 RGD:1624291
G Xrcc1 X-ray repair cross complementing 1 JBrowse link 1 81,412,635 81,441,680 RGD:1624291
G Xrcc4 X-ray repair cross complementing 4 JBrowse link 2 18,674,496 18,927,463 RGD:1624291
negative regulation of t-circle formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Rtel1 regulator of telomere elongation helicase 1 JBrowse link 3 176,818,012 176,856,531 RGD:1624291
RGD:13792537
G Terf2 telomeric repeat binding factor 2 JBrowse link 19 39,271,992 39,301,506 RGD:1624291
G Xrcc5 X-ray repair cross complementing 5 JBrowse link 9 79,659,275 79,748,050 RGD:1624291
negative regulation of telomere capping term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atm ATM serine/threonine kinase JBrowse link 8 58,015,938 58,119,973 RGD:1624291
G Nbn nibrin JBrowse link 5 29,622,347 29,656,877 RGD:1624291
RGD:1600115
G Rad50 RAD50 double strand break repair protein JBrowse link 10 39,002,130 39,054,042 RGD:1624291
G Smg6 SMG6 nonsense mediated mRNA decay factor JBrowse link 10
10
61,526,024
61,771,912
61,542,583
62,007,030
RGD:1624291
G Terf2 telomeric repeat binding factor 2 JBrowse link 19 39,271,992 39,301,506 RGD:1624291
negative regulation of telomere maintenance term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit JBrowse link 1 80,256,973 80,268,198 RGD:1624291
G Ercc4 ERCC excision repair 4, endonuclease catalytic subunit JBrowse link 10 2,010,140 2,037,953 RGD:1624291
G Terf2 telomeric repeat binding factor 2 JBrowse link 19 39,271,992 39,301,506 RGD:1624291
G Terf2ip TERF2 interacting protein JBrowse link 19 44,231,317 44,238,406 RGD:1624291
G Tinf2 TERF1 interacting nuclear factor 2 JBrowse link 15 34,358,697 34,365,085 RGD:1624291
negative regulation of telomere maintenance in response to DNA damage term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Rtel1 regulator of telomere elongation helicase 1 JBrowse link 3 176,818,012 176,856,531 RGD:1624291
negative regulation of telomere maintenance via recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Terf2 telomeric repeat binding factor 2 JBrowse link 19 39,271,992 39,301,506 RGD:1624291
RGD:13792537
negative regulation of telomere maintenance via telomerase term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acd ACD, shelterin complex subunit and telomerase recruitment factor JBrowse link 19 37,665,289 37,668,043 RGD:1624291
RGD:13792537
G Ctc1 CST telomere replication complex component 1 JBrowse link 10 55,596,172 55,616,873 RGD:1624291
G Dcp2 decapping mRNA 2 JBrowse link 18 35,489,274 35,671,676 RGD:1624291
G Exosc10 exosome component 10 JBrowse link 5 165,374,964 165,398,195 RGD:1624291
G Gnl3l G protein nucleolar 3 like JBrowse link X 20,037,558 20,070,505 RGD:1624291
G Hnrnpa1 heterogeneous nuclear ribonucleoprotein A1 JBrowse link 7 144,865,302 144,871,592 RGD:1624291
RGD:1600115
G Hnrnpc heterogeneous nuclear ribonucleoprotein C JBrowse link 15 28,486,605 28,517,353 RGD:1624291
G Hnrnpu heterogeneous nuclear ribonucleoprotein U JBrowse link 13 96,222,093 96,238,845 RGD:1624291
RGD:13792537
RGD:1600115
G Nat10 N-acetyltransferase 10 JBrowse link 3 93,658,119 93,698,136 RGD:1624291
G Pif1 PIF1 5'-to-3' DNA helicase JBrowse link 8 71,124,477 71,133,460 RGD:1624291
G Pinx1 PIN2/TERF1 interacting, telomerase inhibitor 1 JBrowse link 15 47,211,682 47,270,343 RGD:1624291
G Pml promyelocytic leukemia JBrowse link 8 63,002,515 63,034,310 RGD:1624291
G Pot1 protection of telomeres 1 JBrowse link 4 51,888,632 51,946,764 RGD:1624291
G Src SRC proto-oncogene, non-receptor tyrosine kinase JBrowse link 3 153,547,807 153,595,643 RGD:1624291
G Stn1 STN1 subunit of CST complex JBrowse link 1 267,281,786 267,315,714 RGD:1600115
RGD:1624291
G Ten1 TEN1 subunit of CST complex JBrowse link 10 105,073,077 105,095,094 RGD:1624291
RGD:13792537
G Tent4b terminal nucleotidyltransferase 4B JBrowse link 19 19,771,289 19,834,759 RGD:1624291
G Terf1 telomeric repeat binding factor 1 JBrowse link 5 2,853,455 2,882,731 RGD:1624291
G Terf2 telomeric repeat binding factor 2 JBrowse link 19 39,271,992 39,301,506 RGD:1624291
G Tinf2 TERF1 interacting nuclear factor 2 JBrowse link 15 34,358,697 34,365,085 RGD:1624291
negative regulation of telomere maintenance via telomere lengthening term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ercc4 ERCC excision repair 4, endonuclease catalytic subunit JBrowse link 10 2,010,140 2,037,953 RGD:1624291
G Mcrs1 microspherule protein 1 JBrowse link 7 140,910,420 140,919,234 RGD:1624291
G Parp1 poly (ADP-ribose) polymerase 1 JBrowse link 13 98,857,255 98,889,444 RGD:1624291
G Slx1b SLX1 homolog B, structure-specific endonuclease subunit JBrowse link 1 198,114,514 198,120,061 RGD:1624291
G Slx4 SLX4 structure-specific endonuclease subunit JBrowse link 10 11,787,756 11,808,326 RGD:1624291
G Terf2 telomeric repeat binding factor 2 JBrowse link 19 39,271,992 39,301,506 RGD:1624291
G Tnks tankyrase JBrowse link 16 60,925,093 61,067,192 RGD:1624291
G Tnks2 tankyrase 2 RGD:1624291
negative regulation of telomeric D-loop disassembly term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Terf1 telomeric repeat binding factor 1 JBrowse link 5 2,853,455 2,882,731 RGD:1624291
RGD:13792537
G Terf2 telomeric repeat binding factor 2 JBrowse link 19 39,271,992 39,301,506 RGD:1624291
RGD:13792537
positive regulation of t-circle formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit JBrowse link 1 80,256,973 80,268,198 RGD:1624291
G Slx1b SLX1 homolog B, structure-specific endonuclease subunit JBrowse link 1 198,114,514 198,120,061 RGD:1624291
G Slx4 SLX4 structure-specific endonuclease subunit JBrowse link 10 11,787,756 11,808,326 RGD:1624291
positive regulation of telomere capping term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aurkb aurora kinase B JBrowse link 10 55,625,860 55,632,399 RGD:1624291
G Hnrnpd heterogeneous nuclear ribonucleoprotein D JBrowse link 14 11,256,163 11,274,684 RGD:1624291
G Map2k7 mitogen activated protein kinase kinase 7 JBrowse link 12 2,546,278 2,555,310 RGD:1624291
RGD:1600115
G Map3k4 mitogen activated protein kinase kinase kinase 4 JBrowse link 1 48,625,714 48,711,642 RGD:1624291
G Mapk1 mitogen activated protein kinase 1 JBrowse link 11 88,203,863 88,273,301 RGD:1624291
G Mapk15 mitogen-activated protein kinase 15 JBrowse link 7 117,041,287 117,061,799 RGD:1624291
RGD:1600115
G Mapk3 mitogen activated protein kinase 3 JBrowse link 1 198,192,773 198,198,975 RGD:1624291
G Mapkapk5 MAPK activated protein kinase 5 JBrowse link 12 40,510,378 40,529,332 RGD:1624291
G Nabp2 nucleic acid binding protein 2 JBrowse link 7 2,820,006 2,825,627 RGD:1624291
RGD:1600115
G Nek2 NIMA-related kinase 2 JBrowse link 13 110,511,546 110,524,750 RGD:1624291
G Nek7 NIMA-related kinase 7 JBrowse link 13 55,485,759 55,617,534 RGD:1624291
RGD:1600115
G Pkib cAMP-dependent protein kinase inhibitor beta JBrowse link 20 40,616,868 40,712,598 RGD:1624291
RGD:1600115
G Pnkp polynucleotide kinase 3'-phosphatase JBrowse link 1 100,853,475 100,859,202 RGD:1624291
G Prkcq protein kinase C, theta JBrowse link 17 70,971,915 71,105,286 RGD:1624291
RGD:1600115
G Rtel1 regulator of telomere elongation helicase 1 JBrowse link 3 176,818,012 176,856,531 RGD:1624291
G Tnks tankyrase JBrowse link 16 60,925,093 61,067,192 RGD:1624291
RGD:13792537
G Tnks2 tankyrase 2 RGD:1624291
RGD:13792537
positive regulation of telomere maintenance term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atrx ATRX, chromatin remodeler JBrowse link X 76,820,110 76,979,155 RGD:1600115
RGD:1624291
G Dhx36 DEAH-box helicase 36 JBrowse link 2 152,785,844 152,824,549 RGD:1624291
G Gnl3 G protein nucleolar 3 JBrowse link 16 7,097,580 7,103,518 RGD:1624291
G Mre11 MRE11 homolog, double strand break repair nuclease JBrowse link 8 13,304,355 13,350,329 RGD:1624291
RGD:1600115
G Nbn nibrin JBrowse link 5 29,622,347 29,656,877 RGD:1624291
RGD:1600115
G Pml promyelocytic leukemia JBrowse link 8 63,002,515 63,034,310 RGD:1624291
G Ppp1r10 protein phosphatase 1, regulatory subunit 10 JBrowse link 20 3,329,677 3,344,286 RGD:1600115
RGD:1624291
G Rad50 RAD50 double strand break repair protein JBrowse link 10 39,002,130 39,054,042 RGD:1624291
G Rtel1 regulator of telomere elongation helicase 1 JBrowse link 3 176,818,012 176,856,531 RGD:1624291
G Sirt6 sirtuin 6 JBrowse link 7 10,937,622 10,943,048 RGD:1624291
G Terf2 telomeric repeat binding factor 2 JBrowse link 19 39,271,992 39,301,506 RGD:1624291
positive regulation of telomere maintenance via telomerase term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acd ACD, shelterin complex subunit and telomerase recruitment factor JBrowse link 19 37,665,289 37,668,043 RGD:1624291
G Atm ATM serine/threonine kinase JBrowse link 8 58,015,938 58,119,973 RGD:1624291
G Atr ATR serine/threonine kinase JBrowse link 8 103,673,578 103,770,886 RGD:1624291
G Aurkb aurora kinase B JBrowse link 10 55,625,860 55,632,399 RGD:1624291
G Cct2 chaperonin containing TCP1 subunit 2 JBrowse link 7 60,106,532 60,122,779 RGD:1624291
G Cct3 chaperonin containing TCP1 subunit 3 JBrowse link 2 187,669,051 187,693,610 RGD:1624291
G Cct4 chaperonin containing TCP1 subunit 4 JBrowse link 14 107,767,392 107,780,270 RGD:1624291
G Cct5 chaperonin containing TCP1 subunit 5 JBrowse link 2 84,667,578 84,678,730 RGD:1624291
G Cct6a chaperonin containing TCP1 subunit 6A JBrowse link 12 30,491,584 30,501,813 RGD:1624291
G Cct7 chaperonin containing TCP1 subunit 7 JBrowse link 4 117,235,023 117,252,265 RGD:1624291
G Cct8 chaperonin containing TCP1 subunit 8 JBrowse link 11 27,130,172 27,141,881 RGD:1624291
G Ctnnb1 catenin beta 1 JBrowse link 8 129,601,511 129,628,378 RGD:1624291
RGD:1600115
G Dkc1 dyskerin pseudouridine synthase 1 JBrowse link X 155,844,914 155,862,363 RGD:1624291
G Fbxo4 F-box protein 4 JBrowse link 2 53,797,954 53,811,134 RGD:1624291
G Hmbox1 homeobox containing 1 JBrowse link 15 48,194,709 48,326,310 RGD:1624291
RGD:13792537
G Hnrnpa1 heterogeneous nuclear ribonucleoprotein A1 JBrowse link 7 144,865,302 144,871,592 RGD:1624291
RGD:1600115
G Map2k7 mitogen activated protein kinase kinase 7 JBrowse link 12 2,546,278 2,555,310 RGD:1624291
RGD:1600115
G Map3k4 mitogen activated protein kinase kinase kinase 4 JBrowse link 1 48,625,714 48,711,642 RGD:1624291
G Mapk1 mitogen activated protein kinase 1 JBrowse link 11 88,203,863 88,273,301 RGD:1624291
G Mapk15 mitogen-activated protein kinase 15 JBrowse link 7 117,041,287 117,061,799 RGD:1624291
RGD:1600115
G Mapk3 mitogen activated protein kinase 3 JBrowse link 1 198,192,773 198,198,975 RGD:1624291
G Mapkapk5 MAPK activated protein kinase 5 JBrowse link 12 40,510,378 40,529,332 RGD:1624291
G Nek2 NIMA-related kinase 2 JBrowse link 13 110,511,546 110,524,750 RGD:1624291
G Nek7 NIMA-related kinase 7 JBrowse link 13 55,485,759 55,617,534 RGD:1624291
RGD:1600115
G Parn poly(A)-specific ribonuclease JBrowse link 10 1,309,724 1,461,123 RGD:1624291
G Pkib cAMP-dependent protein kinase inhibitor beta JBrowse link 20 40,616,868 40,712,598 RGD:1624291
RGD:1600115
G Pnkp polynucleotide kinase 3'-phosphatase JBrowse link 1 100,853,475 100,859,202 RGD:1624291
G Pot1 protection of telomeres 1 JBrowse link 4 51,888,632 51,946,764 RGD:1624291
G Prkcq protein kinase C, theta JBrowse link 17 70,971,915 71,105,286 RGD:1624291
RGD:1600115
G Tcp1 t-complex 1 JBrowse link 1 48,025,664 48,033,343 RGD:1624291
G Terc telomerase RNA component JBrowse link 2 116,432,723 116,433,110 RGD:1624291
G Tnks tankyrase JBrowse link 16 60,925,093 61,067,192 RGD:1624291
G Xrcc5 X-ray repair cross complementing 5 JBrowse link 9 79,659,275 79,748,050 RGD:1624291
positive regulation of telomere maintenance via telomere lengthening term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atm ATM serine/threonine kinase JBrowse link 8 58,015,938 58,119,973 RGD:1624291
G Dhx36 DEAH-box helicase 36 JBrowse link 2 152,785,844 152,824,549 RGD:1624291
G Hnrnpa2b1 heterogeneous nuclear ribonucleoprotein A2/B1 JBrowse link 4 81,237,496 81,241,281 RGD:11567256
G Naf1 nuclear assembly factor 1 ribonucleoprotein JBrowse link 16 24,582,000 24,612,773 RGD:1624291
RGD:1600115
G Rtel1 regulator of telomere elongation helicase 1 JBrowse link 3 176,818,012 176,856,531 RGD:1624291
positive regulation of telomeric loop disassembly term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Rtel1 regulator of telomere elongation helicase 1 JBrowse link 3 176,818,012 176,856,531 RGD:1624291
protection from non-homologous end joining at telomere term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acd ACD, shelterin complex subunit and telomerase recruitment factor JBrowse link 19 37,665,289 37,668,043 RGD:1624291
G Dclre1a DNA cross-link repair 1A JBrowse link 1 277,335,792 277,355,701 RGD:13792537
G Dclre1b DNA cross-link repair 1B JBrowse link 2 206,285,085 206,293,599 RGD:1600115
RGD:13792537
RGD:1624291
G Dclre1c DNA cross-link repair 1C JBrowse link 17 78,782,512 78,812,140 RGD:13792537
G Pot1b protection of telomeres 1B JBrowse link 9 7,845,697 7,902,270 RGD:1600115
G Terf2 telomeric repeat binding factor 2 JBrowse link 19 39,271,992 39,301,506 RGD:1624291
RGD:13792537
G Terf2ip TERF2 interacting protein JBrowse link 19 44,231,317 44,238,406 RGD:1624291
RGD:1600115
regulation of telomere maintenance term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hdac8 histone deacetylase 8 JBrowse link X 72,163,777 72,370,058 RGD:1624291
G Hnrnpd heterogeneous nuclear ribonucleoprotein D JBrowse link 14 11,256,163 11,274,684 RGD:1624291
G Lmna lamin A/C JBrowse link 2 187,842,884 187,863,552 RGD:1624291
G Myc MYC proto-oncogene, bHLH transcription factor JBrowse link 7 102,586,313 102,591,240 RGD:1624291
RGD:1600115
G Pif1 PIF1 5'-to-3' DNA helicase JBrowse link 8 71,124,477 71,133,460 RGD:1624291
G Smg1 SMG1, nonsense mediated mRNA decay associated PI3K related kinase JBrowse link 1 187,781,577 187,882,833 RGD:1624291
G Smg5 SMG5 nonsense mediated mRNA decay factor JBrowse link 2 187,708,247 187,735,355 RGD:1624291
G Smg6 SMG6 nonsense mediated mRNA decay factor JBrowse link 10
10
61,526,024
61,771,912
61,542,583
62,007,030
RGD:1624291
G Terf2 telomeric repeat binding factor 2 JBrowse link 19 39,271,992 39,301,506 RGD:1624291
G Terf2ip TERF2 interacting protein JBrowse link 19 44,231,317 44,238,406 RGD:1624291
G Upf1 UPF1, RNA helicase and ATPase JBrowse link 16 20,824,888 20,845,632 RGD:1624291
G Ylpm1 YLP motif containing 1 JBrowse link 6 108,820,774 108,897,209 RGD:1624291
RGD:13792537
regulation of telomere maintenance via telomerase term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atm ATM serine/threonine kinase JBrowse link 8 58,015,938 58,119,973 RGD:1624291
G Pot1 protection of telomeres 1 JBrowse link 4 51,888,632 51,946,764 RGD:1624291
RGD:13792537
G Pot1b protection of telomeres 1B JBrowse link 9 7,845,697 7,902,270 RGD:13792537
G Smg5 SMG5 nonsense mediated mRNA decay factor JBrowse link 2 187,708,247 187,735,355 RGD:13792537
G Smg6 SMG6 nonsense mediated mRNA decay factor JBrowse link 10
10
61,526,024
61,771,912
61,542,583
62,007,030
RGD:13792537
G Smg7 SMG7 nonsense mediated mRNA decay factor JBrowse link 13 70,258,919 70,321,886 RGD:13792537
G Terf2 telomeric repeat binding factor 2 JBrowse link 19 39,271,992 39,301,506 RGD:1624291
RGD:13792537
regulation of telomere maintenance via telomere lengthening term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Tinf2 TERF1 interacting nuclear factor 2 JBrowse link 15 34,358,697 34,365,085 RGD:1624291
RGD:13792537
t-circle formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit JBrowse link 1 80,256,973 80,268,198 RGD:1624291
G Nbn nibrin JBrowse link 5 29,622,347 29,656,877 RGD:1624291
RGD:1600115
G Slx1b SLX1 homolog B, structure-specific endonuclease subunit JBrowse link 1 198,114,514 198,120,061 RGD:1624291
G Slx4 SLX4 structure-specific endonuclease subunit JBrowse link 10 11,787,756 11,808,326 RGD:1624291
G Xrcc3 X-ray repair cross complementing 3 JBrowse link 6 136,366,917 136,380,751 RGD:1624291
RGD:13792537
telomere capping term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acd ACD, shelterin complex subunit and telomerase recruitment factor JBrowse link 19 37,665,289 37,668,043 RGD:1624291
RGD:13792537
G Dclre1b DNA cross-link repair 1B JBrowse link 2 206,285,085 206,293,599 RGD:1624291
G Hnrnpa2b1 heterogeneous nuclear ribonucleoprotein A2/B1 JBrowse link 4 81,237,496 81,241,281 RGD:10680046
G Nbn nibrin JBrowse link 5 29,622,347 29,656,877 RGD:13792537
G Pot1 protection of telomeres 1 JBrowse link 4 51,888,632 51,946,764 RGD:1624291
RGD:13792537
G Pot1b protection of telomeres 1B JBrowse link 9 7,845,697 7,902,270 RGD:13792537
G Prkdc protein kinase, DNA-activated, catalytic subunit JBrowse link 11 89,293,547 89,510,948 RGD:1624291
G Rad50 RAD50 double strand break repair protein JBrowse link 10 39,002,130 39,054,042 RGD:13792537
G Stn1 STN1 subunit of CST complex JBrowse link 1 267,281,786 267,315,714 RGD:1600115
G Terf2 telomeric repeat binding factor 2 JBrowse link 19 39,271,992 39,301,506 RGD:1624291
G Tinf2 TERF1 interacting nuclear factor 2 JBrowse link 15 34,358,697 34,365,085 RGD:1624291
RGD:13792537
telomere maintenance in response to DNA damage term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Rif1 replication timing regulatory factor 1 JBrowse link 3 37,599,540 37,648,818 RGD:1624291
G Rtel1 regulator of telomere elongation helicase 1 JBrowse link 3 176,818,012 176,856,531 RGD:1624291
telomere maintenance via base-excision repair term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 JBrowse link 15 27,849,943 27,852,083 RGD:1624291
telomere maintenance via recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Brca2 BRCA2, DNA repair associated JBrowse link 12 503,660 544,754 RGD:1624291
RGD:1600115
G Nsmce2 NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase JBrowse link 7 99,677,295 99,900,765 RGD:1624291
RGD:1600115
G Rad50 RAD50 double strand break repair protein JBrowse link 10 39,002,130 39,054,042 RGD:13792537
G Rad51 RAD51 recombinase JBrowse link 3 110,918,240 110,942,920 RGD:1624291
G Rad51c RAD51 paralog C JBrowse link 10 74,697,713 74,724,004 RGD:1624291
G Smc5 structural maintenance of chromosomes 5 JBrowse link 1 240,977,898 241,046,273 RGD:1624291
G Smc6 structural maintenance of chromosomes 6 JBrowse link 6 36,941,233 36,995,920 RGD:1624291
G Tep1 telomerase associated protein 1 JBrowse link 15 27,751,186 27,798,839 RGD:1600115
RGD:13792537
RGD:1624291
G Xrcc3 X-ray repair cross complementing 3 JBrowse link 6 136,366,917 136,380,751 RGD:1624291
RGD:13792537
telomere maintenance via semi-conservative replication term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Upf1 UPF1, RNA helicase and ATPase JBrowse link 16 20,824,888 20,845,632 RGD:1624291
telomere maintenance via telomerase term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dkc1 dyskerin pseudouridine synthase 1 JBrowse link X 155,844,914 155,862,363 RGD:1600115
RGD:1624291
G Gar1 GAR1 ribonucleoprotein JBrowse link 2 235,250,453 235,258,464 RGD:1600115
RGD:1624291
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 JBrowse link 6 135,107,262 135,112,793 RGD:1624291
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 JBrowse link 9 17,817,791 17,823,163 RGD:1624291
G Nhp2 NHP2 ribonucleoprotein JBrowse link 10 34,975,701 34,979,082 RGD:1624291
G Nop10 NOP10 ribonucleoprotein JBrowse link 3 103,747,654 103,748,739 RGD:1624291
G Parp4 poly (ADP-ribose) polymerase family, member 4 JBrowse link 15 36,809,362 36,911,167 RGD:1624291
G Pinx1 PIN2/TERF1 interacting, telomerase inhibitor 1 JBrowse link 15 47,211,682 47,270,343 RGD:1624291
G Pot1 protection of telomeres 1 JBrowse link 4 51,888,632 51,946,764 RGD:1624291
G Ptges3 prostaglandin E synthase 3 JBrowse link 7 2,479,267 2,497,024 RGD:1624291
RGD:13792537
G Ptges3l1 prostaglandin E synthase 3-like 1 JBrowse link X 45,410,545 45,419,817 RGD:13792537
G Rad50 RAD50 double strand break repair protein JBrowse link 10 39,002,130 39,054,042 RGD:1624291
RGD:13792537
RGD:1600115
G Rpa1 replication protein A1 JBrowse link 10 62,140,419 62,191,518 RGD:13792537
G Smg5 SMG5 nonsense mediated mRNA decay factor JBrowse link 2 187,708,247 187,735,355 RGD:13792537
G Smg6 SMG6 nonsense mediated mRNA decay factor JBrowse link 10
10
61,526,024
61,771,912
61,542,583
62,007,030
RGD:13792537
G Smg7 SMG7 nonsense mediated mRNA decay factor JBrowse link 13 70,258,919 70,321,886 RGD:13792537
G Telo2 telomere maintenance 2 JBrowse link 10 14,461,581 14,476,812 RGD:13792537
G Tep1 telomerase associated protein 1 JBrowse link 15 27,751,186 27,798,839 RGD:1624291
G Terc telomerase RNA component JBrowse link 2 116,432,723 116,433,110 RGD:1299555
RGD:1624291
G Terf1 telomeric repeat binding factor 1 JBrowse link 5 2,853,455 2,882,731 RGD:1624291
RGD:13792537
G Tert telomerase reverse transcriptase JBrowse link 1 32,250,876 32,275,330 RGD:1600115
RGD:13792537
RGD:1624291
G Wrap53 WD repeat containing, antisense to TP53 JBrowse link 10 56,169,024 56,185,800 RGD:1600115
RGD:1624291
telomere maintenance via telomere lengthening term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ctc1 CST telomere replication complex component 1 JBrowse link 10 55,596,172 55,616,873 RGD:1624291
RGD:13792537
G Dclre1b DNA cross-link repair 1B JBrowse link 2 206,285,085 206,293,599 RGD:1624291
RGD:1600115
G Rad51 RAD51 recombinase JBrowse link 3 110,918,240 110,942,920 RGD:1624291
G Slx1b SLX1 homolog B, structure-specific endonuclease subunit JBrowse link 1 198,114,514 198,120,061 RGD:1624291
G Stn1 STN1 subunit of CST complex JBrowse link 1 267,281,786 267,315,714 RGD:1624291
RGD:1600115
G Terf2ip TERF2 interacting protein JBrowse link 19 44,231,317 44,238,406 RGD:1600115
RGD:13792537
RGD:1624291
G Zbtb48 zinc finger and BTB domain containing 48 JBrowse link 5 169,191,771 169,200,140 RGD:1624291
telomere maintenance via telomere trimming term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nbn nibrin JBrowse link 5 29,622,347 29,656,877 RGD:1624291
G Xrcc3 X-ray repair cross complementing 3 JBrowse link 6 136,366,917 136,380,751 RGD:1624291
telomeric 3' overhang formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dclre1b DNA cross-link repair 1B JBrowse link 2 206,285,085 206,293,599 RGD:1600115
RGD:1624291
G Mre11 MRE11 homolog, double strand break repair nuclease JBrowse link 8 13,304,355 13,350,329 RGD:1624291
RGD:1600115
G Nbn nibrin JBrowse link 5 29,622,347 29,656,877 RGD:1624291
RGD:1600115
G Rad50 RAD50 double strand break repair protein JBrowse link 10 39,002,130 39,054,042 RGD:1624291
telomeric D-loop disassembly term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Blm BLM RecQ like helicase JBrowse link 1 142,246,773 142,332,616 RGD:1624291
G Pot1 protection of telomeres 1 JBrowse link 4 51,888,632 51,946,764 RGD:1624291
G Recql4 RecQ like helicase 4 JBrowse link 7 117,765,892 117,773,128 RGD:1624291
G Slx1b SLX1 homolog B, structure-specific endonuclease subunit JBrowse link 1 198,114,514 198,120,061 RGD:1624291
G Slx4 SLX4 structure-specific endonuclease subunit JBrowse link 10 11,787,756 11,808,326 RGD:1624291
G Terf1 telomeric repeat binding factor 1 JBrowse link 5 2,853,455 2,882,731 RGD:1624291
G Terf2 telomeric repeat binding factor 2 JBrowse link 19 39,271,992 39,301,506 RGD:1624291
RGD:13792537
G Wrn WRN RecQ like helicase JBrowse link 16 62,483,773 62,619,018 RGD:1624291
telomeric DNA-containing double minutes formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit JBrowse link 1 80,256,973 80,268,198 RGD:1624291
G Ercc4 ERCC excision repair 4, endonuclease catalytic subunit JBrowse link 10 2,010,140 2,037,953 RGD:1624291
G Xrcc1 X-ray repair cross complementing 1 JBrowse link 1 81,412,635 81,441,680 RGD:1624291
G Xrcc4 X-ray repair cross complementing 4 JBrowse link 2 18,674,496 18,927,463 RGD:1624291
telomeric loop disassembly term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Rtel1 regulator of telomere elongation helicase 1 JBrowse link 3 176,818,012 176,856,531 RGD:1624291
RGD:13792537
telomeric loop formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dclre1b DNA cross-link repair 1B JBrowse link 2 206,285,085 206,293,599 RGD:1600115
RGD:1624291
G Pot1 protection of telomeres 1 JBrowse link 4 51,888,632 51,946,764 RGD:1624291
G Terf1 telomeric repeat binding factor 1 JBrowse link 5 2,853,455 2,882,731 RGD:1624291
G Terf2 telomeric repeat binding factor 2 JBrowse link 19 39,271,992 39,301,506 RGD:1624291
RGD:13792537
G Terf2ip TERF2 interacting protein JBrowse link 19 44,231,317 44,238,406 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19439
    biological regulation 13444
      regulation of biological quality 4273
        homeostatic process 2048
          anatomical structure homeostasis 435
            telomere maintenance 126
              negative regulation of telomere maintenance + 37
              positive regulation of telomere maintenance + 52
              regulation of telomere maintenance + 83
              telomere capping + 38
              telomere maintenance in response to DNA damage + 14
              telomere maintenance via recombination + 14
              telomere maintenance via semi-conservative replication + 3
              telomere maintenance via telomere lengthening + 82
              telomere maintenance via telomere trimming + 8
              telomeric loop disassembly + 9
              telomeric loop formation + 5
Path 2
Term Annotations click to browse term
  biological_process 19439
    cellular process 18178
      cellular metabolic process 10639
        cellular nitrogen compound metabolic process 6377
          nucleobase-containing compound metabolic process 5274
            nucleic acid metabolic process 4784
              DNA metabolic process 885
                telomere maintenance 126
                  negative regulation of telomere maintenance + 37
                  positive regulation of telomere maintenance + 52
                  regulation of telomere maintenance + 83
                  telomere capping + 38
                  telomere maintenance in response to DNA damage + 14
                  telomere maintenance via recombination + 14
                  telomere maintenance via semi-conservative replication + 3
                  telomere maintenance via telomere lengthening + 82
                  telomere maintenance via telomere trimming + 8
                  telomeric loop disassembly + 9
                  telomeric loop formation + 5
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.