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ONTOLOGY REPORT - ANNOTATIONS


Term:kinetochore
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Accession:GO:0000776 term browser browse the term
Definition:A multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules.
Comment:Note that the kinetochore overlaps the centromeric DNA, but centromeric DNA is not part of the kinetochore.
Synonyms:alt_id: GO:0005699
 xref: Wikipedia:Kinetochore


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kinetochore term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AABR07066944.1 RGD:13792537
G Anapc16 anaphase promoting complex subunit 16 JBrowse link 20 29,544,626 29,558,928 RGD:1624291
RGD:13792537
G Apc APC regulator of WNT signaling pathway JBrowse link 18 27,011,710 27,106,323 RGD:1624291
RGD:1600115
G Aurkb aurora kinase B JBrowse link 10 55,625,860 55,632,399 RGD:1624291
G Bub1 BUB1 mitotic checkpoint serine/threonine kinase JBrowse link 3 120,373,604 120,404,910 RGD:1624291
G Bub1b BUB1 mitotic checkpoint serine/threonine kinase B JBrowse link 3 110,367,949 110,420,471 RGD:1624291
G Bub3 BUB3 mitotic checkpoint protein JBrowse link 1 203,526,853 203,537,459 RGD:1624291
RGD:13792537
G Cbx5 chromobox 5 JBrowse link 7 144,819,673 144,865,014 RGD:1624291
G Cdt1 chromatin licensing and DNA replication factor 1 JBrowse link 19 55,381,565 55,386,511 RGD:1624291
G Cenpc centromere protein C JBrowse link 14 23,611,909 23,670,314 RGD:1624291
G Cenpe centromere protein E JBrowse link 2 240,395,974 240,454,785 RGD:1624291
G Cenpf centromere protein F JBrowse link 13 108,132,499 108,178,609 RGD:1624291
G Cenph centromere protein H JBrowse link 2 30,766,637 30,780,123 RGD:1624291
RGD:13792537
G Cenpi centromere protein I JBrowse link X 105,147,045 105,198,798 RGD:1600115
RGD:1624291
G Cenpq centromere protein Q JBrowse link 9 23,352,271 23,368,774 RGD:13792537
G Cenpt centromere protein T JBrowse link 19 37,813,284 37,819,782 RGD:1624291
G Cenpv centromere protein V JBrowse link 10 48,846,513 48,861,893 RGD:1624291
RGD:13792537
G Cenpw centromere protein W JBrowse link 1 29,915,443 29,920,598 RGD:1624291
RGD:13792537
RGD:1600115
G Ckap5 cytoskeleton associated protein 5 JBrowse link 3 80,424,320 80,526,583 RGD:1624291
RGD:13792537
G Clasp1 cytoplasmic linker associated protein 1 JBrowse link 13 34,365,038 34,584,651 RGD:1624291
RGD:13792537
G Clasp2 cytoplasmic linker associated protein 2 JBrowse link 8 122,003,719 122,185,495 RGD:1624291
RGD:13792537
RGD:1600115
G Dctn1 dynactin subunit 1 JBrowse link 4 114,876,770 114,896,567 RGD:1600115
RGD:13792537
RGD:1624291
G Dctn2 dynactin subunit 2 JBrowse link 7 70,555,953 70,571,433 RGD:1331348
RGD:1624291
RGD:1600115
G Dctn4 dynactin subunit 4 JBrowse link 18 55,797,188 55,824,195 RGD:70710
G Dync1i1 dynein cytoplasmic 1 intermediate chain 1 JBrowse link 4 30,807,755 31,121,097 RGD:1600115
RGD:1624291
G Dync1li1 dynein cytoplasmic 1 light intermediate chain 1 JBrowse link 8 122,743,274 122,776,801 RGD:1600115
RGD:1624291
RGD:13207422
G Dync1li2 dynein, cytoplasmic 1 light intermediate chain 2 JBrowse link 19 740,007 762,897 RGD:13207422
G Dynll1 dynein light chain LC8-type 1 JBrowse link 12 47,074,200 47,076,573 RGD:1624291
RGD:1600115
G Dynlt3 dynein light chain Tctex-type 3 JBrowse link X 14,633,342 14,642,356 RGD:8554144
RGD:1624291
G Fbxo28 F-box protein 28 JBrowse link 13 100,715,257 100,740,728 RGD:1624291
G Gpatch11 G patch domain containing 11 JBrowse link 6 1,410,461 1,421,506 RGD:1624291
RGD:13792537
G Hnrnpu heterogeneous nuclear ribonucleoprotein U JBrowse link 13 96,222,093 96,238,845 RGD:1600115
RGD:13792537
RGD:1624291
G Hsf1 heat shock transcription factor 1 JBrowse link 7 117,538,523 117,565,478 RGD:1624291
G Incenp inner centromere protein JBrowse link 1 225,923,448 225,953,384 RGD:1624291
RGD:13792537
G Kat2b lysine acetyltransferase 2B JBrowse link 9 4,440,982 4,492,949 RGD:1624291
G Kat8 lysine acetyltransferase 8 JBrowse link 1 199,360,645 199,372,925 RGD:1624291
G Kif18a kinesin family member 18A JBrowse link 3 100,366,168 100,426,867 RGD:1624291
G Kif2c kinesin family member 2C JBrowse link 5 136,027,923 136,053,268 RGD:1600115
RGD:1624291
G Knstrn kinetochore-localized astrin/SPAG5 binding protein JBrowse link 3 110,618,256 110,638,024 RGD:1624291
RGD:1600115
G LOC103690005 tubulin-folding cofactor B JBrowse link 1 91,042,805 91,048,487 RGD:13792537
G Lrwd1 leucine-rich repeats and WD repeat domain containing 1 JBrowse link 12 23,574,234 23,587,262 RGD:1624291
G Mad1l1 mitotic arrest deficient 1 like 1 JBrowse link 12 16,410,083 16,721,232 RGD:1624291
RGD:13792537
G Mad2l1 mitotic arrest deficient 2 like 1 JBrowse link 4 97,530,993 97,543,179 RGD:1624291
RGD:13792537
G Meaf6 MYST/Esa1-associated factor 6 JBrowse link 5 143,081,298 143,103,225 RGD:1624291
G Mtbp MDM2 binding protein JBrowse link 7 95,309,928 95,392,418 RGD:1624291
G Ndc80 NDC80 kinetochore complex component JBrowse link 9 119,837,857 119,871,435 RGD:1624291
G Nde1 nudE neurodevelopment protein 1 JBrowse link 10 860,513 904,624 RGD:1624291
RGD:13792537
G Ndel1 nudE neurodevelopment protein 1-like 1 JBrowse link 10 55,398,919 55,456,654 RGD:1624291
RGD:13792537
G Nek2 NIMA-related kinase 2 JBrowse link 13 110,511,546 110,524,750 RGD:1624291
G Nup107 nucleoporin 107 JBrowse link 7 60,781,724 60,825,225 RGD:1600115
RGD:1624291
G Nup160 nucleoporin 160 JBrowse link 3 79,496,239 79,562,163 RGD:1624291
G Nup37 nucleoporin 37 JBrowse link 7 28,715,299 28,750,978 RGD:1624291
G Nup43 nucleoporin 43 JBrowse link 1 1,771,468 1,781,554 RGD:1624291
G Nup85 nucleoporin 85 JBrowse link 10 104,118,999 104,137,258 RGD:1624291
G Nup98 nucleoporin 98 and 96 precursor JBrowse link 1 167,213,866 167,308,851 RGD:1624291
G Pafah1b1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 JBrowse link 10 61,456,144 61,577,412 RGD:1624291
RGD:13792537
G Pbrm1 polybromo 1 JBrowse link 16 7,103,714 7,202,899 RGD:1624291
G Phf2 PHD finger protein 2 JBrowse link 17 16,240,458 16,274,626 RGD:1624291
G Pinx1 PIN2/TERF1 interacting, telomerase inhibitor 1 JBrowse link 15 47,211,682 47,270,343 RGD:1624291
G Plk1 polo-like kinase 1 JBrowse link 1 192,115,990 192,125,969 RGD:1624291
RGD:1600115
G Ppp1r12a protein phosphatase 1, regulatory subunit 12A JBrowse link 7 51,404,971 51,515,382 RGD:1600115
RGD:1624291
G Psen1 presenilin 1 JBrowse link 6 107,169,514 107,221,000 RGD:1624291
G Psen2 presenilin 2 JBrowse link 13 98,513,600 98,539,347 RGD:1624291
G Rangap1 RAN GTPase activating protein 1 JBrowse link 7 122,939,266 122,967,178 RGD:1624291
G Rassf2 Ras association domain family member 2 JBrowse link 3 124,574,088 124,610,267 RGD:1600115
RGD:1624291
G Sec13 SEC13 homolog, nuclear pore and COPII coat complex component JBrowse link 4 145,686,186 145,699,577 RGD:1624291
G Seh1l SEH1-like nucleoporin JBrowse link 18 63,545,150 63,568,101 RGD:1624291
G Sgo1 shugoshin 1 JBrowse link 9 4,420,158 4,435,939 RGD:1624291
G Sgo2 shugoshin 2 JBrowse link 9 64,898,380 64,923,023 RGD:1624291
G Sin3a SIN3 transcription regulator family member A JBrowse link 8 61,748,590 61,803,314 RGD:1624291
G Ska3 spindle and kinetochore associated complex subunit 3 JBrowse link 15 38,077,903 38,097,100 RGD:1624291
RGD:1600115
G Smc1a structural maintenance of chromosomes 1A JBrowse link X 21,710,976 21,755,708 RGD:1600115
RGD:1624291
G Spag5 sperm associated antigen 5 JBrowse link 10 65,552,780 65,585,773 RGD:1624291
G Spout1 SPOUT domain containing methyltransferase 1 JBrowse link 3 8,743,890 8,751,634 RGD:1624291
RGD:13792537
G Ss18l1 SS18L1 subunit of BAF chromatin remodeling complex JBrowse link 3 175,426,754 175,445,222 RGD:1624291
G Tbcb tubulin folding cofactor B JBrowse link 1 88,680,936 88,686,785 RGD:13792537
G Tex14 testis expressed 14, intercellular bridge forming factor JBrowse link 10 74,724,070 74,849,172 RGD:1600115
RGD:13792537
RGD:1624291
G Tp53bp1 tumor protein p53 binding protein 1 JBrowse link 3 113,160,030 113,259,701 RGD:1624291
G Tpr translocated promoter region, nuclear basket protein JBrowse link 13 67,611,685 67,672,833 RGD:1624291
RGD:1600115
G Trappc12 trafficking protein particle complex 12 JBrowse link 6 47,954,822 48,020,280 RGD:1624291
G Ttk Ttk protein kinase JBrowse link 8 91,368,065 91,405,995 RGD:1624291
RGD:13792537
G Xpo1 exportin 1 JBrowse link 14 108,007,421 108,049,088 RGD:1624291
RGD:1600115
G Zfp207 zinc finger protein 207 JBrowse link 10 67,762,970 67,784,854 RGD:1624291
RGD:13792537
G Zfp276 zinc finger protein (C2H2 type) 276 JBrowse link 19 56,054,250 56,067,767 RGD:1624291
G Zw10 zw10 kinetochore protein JBrowse link 8 53,365,881 53,390,742 RGD:1600115
RGD:1624291
G Zwilch zwilch kinetochore protein JBrowse link 8 69,089,449 69,121,420 RGD:1624291
G Zwint ZW10 interacting kinetochore protein JBrowse link 20 17,075,781 17,091,715 RGD:1624291
RGD:13792537
condensed chromosome inner kinetochore term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cenpa centromere protein A JBrowse link 6 27,072,259 27,080,863 RGD:1624291
G Orc2 origin recognition complex, subunit 2 JBrowse link 9 65,350,630 65,387,293 RGD:1624291
condensed chromosome kinetochore term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ahctf1 AT hook containing transcription factor 1 JBrowse link 13 98,023,528 98,079,138 RGD:1624291
G Birc5 baculoviral IAP repeat-containing 5 JBrowse link 10 106,856,097 106,864,419 RGD:1624291
RGD:1600115
G Bub1 BUB1 mitotic checkpoint serine/threonine kinase JBrowse link 3 120,373,604 120,404,910 RGD:1624291
G Bub1b BUB1 mitotic checkpoint serine/threonine kinase B JBrowse link 3 110,367,949 110,420,471 RGD:1624291
G Cenpn centromere protein N JBrowse link 19 49,457,461 49,479,989 RGD:1600115
G Cenpu centromere protein U JBrowse link 16 48,898,032 48,921,248 RGD:1600115
G Cenpw centromere protein W JBrowse link 1 29,915,443 29,920,598 RGD:1600115
G Cfdp1 craniofacial development protein 1 JBrowse link 19 43,989,596 44,078,320 RGD:1600115
G Champ1 chromosome alignment maintaining phosphoprotein 1 JBrowse link 16 80,839,373 80,850,340 RGD:1624291
RGD:13792537
G Clasp2 cytoplasmic linker associated protein 2 JBrowse link 8 122,003,719 122,185,495 RGD:1600115
G Csnk1a1 casein kinase 1, alpha 1 JBrowse link 18 56,887,722 56,910,610 RGD:1600115
G Dsn1 DSN1 component of MIS12 kinetochore complex JBrowse link 3 153,101,020 153,115,326 RGD:1624291
G Dync1i1 dynein cytoplasmic 1 intermediate chain 1 JBrowse link 4 30,807,755 31,121,097 RGD:1600115
G Dync1li1 dynein cytoplasmic 1 light intermediate chain 1 JBrowse link 8 122,743,274 122,776,801 RGD:1600115
G Hjurp Holliday junction recognition protein JBrowse link 9 95,347,739 95,362,228 RGD:1624291
G Hnrnpu heterogeneous nuclear ribonucleoprotein U JBrowse link 13 96,222,093 96,238,845 RGD:1600115
G Itgb3bp integrin subunit beta 3 binding protein JBrowse link 5 118,476,410 118,541,928 RGD:1600115
G Kif2b kinesin family member 2B JBrowse link 10 79,095,588 79,097,807 RGD:1600115
G Kif2c kinesin family member 2C JBrowse link 5 136,027,923 136,053,268 RGD:1600115
G Knl1 kinetochore scaffold 1 JBrowse link 3 110,847,304 110,909,807 RGD:13792537
G Knstrn kinetochore-localized astrin/SPAG5 binding protein JBrowse link 3 110,618,256 110,638,024 RGD:1600115
G LOC100911204 protein CASC5-like JBrowse link 3 112,531,429 112,560,698 RGD:1624291
RGD:13792537
G Meikin meiotic kinetochore factor JBrowse link 10 39,726,373 39,776,458 RGD:1624291
RGD:13792537
G Mis12 MIS12 kinetochore complex component JBrowse link 10 57,653,685 57,661,833 RGD:1624291
G Ncapd3 non-SMC condensin II complex, subunit D3 JBrowse link 8 28,075,629 28,145,024 RGD:1624291
G Ndc80 NDC80 kinetochore complex component JBrowse link 9 119,837,857 119,871,435 RGD:1624291
G Nde1 nudE neurodevelopment protein 1 JBrowse link 10 860,513 904,624 RGD:1600115
G Ndel1 nudE neurodevelopment protein 1-like 1 JBrowse link 10 55,398,919 55,456,654 RGD:1600115
G Nsl1 NSL1 component of MIS12 kinetochore complex JBrowse link 13 109,669,646 109,697,849 RGD:1624291
G Nudcd2 NudC domain containing 2 JBrowse link 10 25,890,943 25,896,432 RGD:1600115
G Nup107 nucleoporin 107 JBrowse link 7 60,781,724 60,825,225 RGD:1600115
G Nup133 nucleoporin 133 JBrowse link 19 56,681,965 56,731,404 RGD:1624291
RGD:13792537
G Nup85 nucleoporin 85 JBrowse link 10 104,118,999 104,137,258 RGD:1600115
G Pinx1 PIN2/TERF1 interacting, telomerase inhibitor 1 JBrowse link 15 47,211,682 47,270,343 RGD:1600115
G Pmf1 polyamine-modulated factor 1 JBrowse link 2 187,751,770 187,771,933 RGD:1624291
G Ppp1cc protein phosphatase 1 catalytic subunit gamma JBrowse link 12 39,864,302 39,882,030 RGD:1600115
G Rassf2 Ras association domain family member 2 JBrowse link 3 124,574,088 124,610,267 RGD:1600115
G Septin7 septin 7 JBrowse link 8 26,412,910 26,476,615 RGD:1600115
G Spc25 SPC25 component of NDC80 kinetochore complex JBrowse link 3 55,438,534 55,451,961 RGD:1624291
RGD:13792537
RGD:1600115
G Ss18l1 SS18L1 subunit of BAF chromatin remodeling complex JBrowse link 3 175,426,754 175,445,222 RGD:1600115
G Tex14 testis expressed 14, intercellular bridge forming factor JBrowse link 10 74,724,070 74,849,172 RGD:1600115
G Zw10 zw10 kinetochore protein JBrowse link 8 53,365,881 53,390,742 RGD:1600115
G Zwint ZW10 interacting kinetochore protein JBrowse link 20 17,075,781 17,091,715 RGD:1600115
condensed chromosome outer kinetochore term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bod1 biorientation of chromosomes in cell division 1 JBrowse link 10 16,259,728 16,266,069 RGD:1624291
RGD:13792537
G Bod1l1 biorientation of chromosomes in cell division 1-like 1 JBrowse link 14 73,738,137 73,792,935 RGD:13792537
G Bub1b BUB1 mitotic checkpoint serine/threonine kinase B JBrowse link 3 110,367,949 110,420,471 RGD:1624291
G Cenpe centromere protein E JBrowse link 2 240,395,974 240,454,785 RGD:1624291
G Cenpf centromere protein F JBrowse link 13 108,132,499 108,178,609 RGD:1624291
G Crebbp CREB binding protein JBrowse link 10 11,590,994 11,721,039 RGD:1624291
G Nup133 nucleoporin 133 JBrowse link 19 56,681,965 56,731,404 RGD:1624291
G Ska1 spindle and kinetochore associated complex subunit 1 JBrowse link 18 70,174,316 70,184,368 RGD:1600115
RGD:13792537
RGD:1624291
G Ska2 spindle and kinetochore associated complex subunit 2 JBrowse link 10 74,413,989 74,431,922 RGD:1600115
RGD:13792537
RGD:1624291
G Ska3 spindle and kinetochore associated complex subunit 3 JBrowse link 15 38,077,903 38,097,100 RGD:1624291
RGD:13792537
RGD:1600115
G Spdl1 spindle apparatus coiled-coil protein 1 JBrowse link 10 19,628,070 19,652,914 RGD:1624291
RGD:13792537
RGD:1600115
condensed nuclear chromosome inner kinetochore term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cenpk centromere protein K JBrowse link 2 34,312,766 34,373,945 RGD:13792537
G Dsn1 DSN1 component of MIS12 kinetochore complex JBrowse link 3 153,101,020 153,115,326 RGD:13792537
condensed nuclear chromosome kinetochore term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bub1 BUB1 mitotic checkpoint serine/threonine kinase JBrowse link 3 120,373,604 120,404,910 RGD:13792537
G Bub1b BUB1 mitotic checkpoint serine/threonine kinase B JBrowse link 3 110,367,949 110,420,471 RGD:1624291
RGD:13792537
G Cenpa centromere protein A JBrowse link 6 27,072,259 27,080,863 RGD:1624291
G Cenpc centromere protein C JBrowse link 14 23,611,909 23,670,314 RGD:13792537
G Cenpe centromere protein E JBrowse link 2 240,395,974 240,454,785 RGD:1624291
G Cenpo centromere protein O JBrowse link 6 28,648,804 28,663,527 RGD:13792537
G Cenpt centromere protein T JBrowse link 19 37,813,284 37,819,782 RGD:13792537
G Mis18bp1 MIS18 binding protein 1 JBrowse link 6 86,879,106 86,925,209 RGD:13792537
G Ndc80 NDC80 kinetochore complex component JBrowse link 9 119,837,857 119,871,435 RGD:13792537
G Nuf2 NUF2 component of NDC80 kinetochore complex JBrowse link 13 87,818,456 87,847,223 RGD:13792537
G Peli1 pellino E3 ubiquitin protein ligase 1 JBrowse link 14 106,008,086 106,062,566 RGD:1624291
G Rec8 REC8 meiotic recombination protein JBrowse link 15 34,296,922 34,304,387 RGD:1624291
condensed nuclear chromosome outer kinetochore term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bub1 BUB1 mitotic checkpoint serine/threonine kinase JBrowse link 3 120,373,604 120,404,910 RGD:1624291
G Ccnb1 cyclin B1 JBrowse link 2 30,782,133 30,791,106 RGD:1624291
G Ndc80 NDC80 kinetochore complex component JBrowse link 9 119,837,857 119,871,435 RGD:1624291
G Plk1 polo-like kinase 1 JBrowse link 1 192,115,990 192,125,969 RGD:1624291
RGD:1600115
MIS12/MIND type complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dsn1 DSN1 component of MIS12 kinetochore complex JBrowse link 3 153,101,020 153,115,326 RGD:1624291
G Mis12 MIS12 kinetochore complex component JBrowse link 10 57,653,685 57,661,833 RGD:1624291
RGD:1600115
G Nsl1 NSL1 component of MIS12 kinetochore complex JBrowse link 13 109,669,646 109,697,849 RGD:1624291
RGD:13792537
G Pmf1 polyamine-modulated factor 1 JBrowse link 2 187,751,770 187,771,933 RGD:1624291
Mis6-Sim4 complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cenpo centromere protein O JBrowse link 6 28,648,804 28,663,527 RGD:13792537
Ndc80 complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ndc80 NDC80 kinetochore complex component JBrowse link 9 119,837,857 119,871,435 RGD:1624291
RGD:13792537
G Nuf2 NUF2 component of NDC80 kinetochore complex JBrowse link 13 87,818,456 87,847,223 RGD:1624291
RGD:13792537
RGD:1600115
G Spc24 SPC24 component of NDC80 kinetochore complex JBrowse link 8 22,780,639 22,785,908 RGD:1624291
G Spc25 SPC25 component of NDC80 kinetochore complex JBrowse link 3 55,438,534 55,451,961 RGD:1624291
RGD:13792537
RGD:1600115
nuclear MIS12/MIND complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dsn1 DSN1 component of MIS12 kinetochore complex JBrowse link 3 153,101,020 153,115,326 RGD:13792537
G Mis12 MIS12 kinetochore complex component JBrowse link 10 57,653,685 57,661,833 RGD:13792537
G Pmf1 polyamine-modulated factor 1 JBrowse link 2 187,751,770 187,771,933 RGD:13792537
RZZ complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Kntc1 kinetochore associated 1 JBrowse link 12 38,200,463 38,274,162 RGD:1624291
G Zw10 zw10 kinetochore protein JBrowse link 8 53,365,881 53,390,742 RGD:1624291
RGD:13792537
G Zwilch zwilch kinetochore protein JBrowse link 8 69,089,449 69,121,420 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 19951
    cellular anatomical entity 19598
      supramolecular complex 1232
        kinetochore 127
          NMS complex + 4
          RZZ complex 3
          condensed chromosome kinetochore + 64
Path 2
Term Annotations click to browse term
  cellular_component 19951
    cellular anatomical entity 19598
      organelle 12670
        non-membrane-bounded organelle 4661
          intracellular non-membrane-bounded organelle 4642
            chromosome 1109
              chromosomal region 290
                chromosome, centromeric region 186
                  kinetochore 127
                    NMS complex + 4
                    RZZ complex 3
                    condensed chromosome kinetochore + 64
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.