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Term:nuclear MIS12/MIND complex
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Accession:GO:0000818 term browser browse the term
Definition:A multiprotein kinetochore subcomplex that binds to centromeric chromatin and forms part of the inner kinetochore of a chromosome in the nucleus. It helps to recruit outer kinetochore subunits that will bind to microtubules. Nuclear localization arises in some organisms because the nuclear envelope is not broken down during mitosis. In S. cerevisiae, it consists of at least four proteins: Mtw1p, Nnf1p, Nsl1p, and Dsn1.
Synonyms:exact_synonym: MIND complex;   Mtw1p Including Nnf1p-Nsl1p-Dsn1p complex

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nuclear MIS12/MIND complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dsn1 DSN1 component of MIS12 kinetochore complex JBrowse link 3 153,101,020 153,115,326 RGD:13792537
G Mis12 MIS12 kinetochore complex component JBrowse link 10 57,653,685 57,661,833 RGD:13792537
G Pmf1 polyamine-modulated factor 1 JBrowse link 2 187,751,770 187,771,933 RGD:13792537

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20118
    protein-containing complex 5964
      MIS12/MIND type complex 4
        nuclear MIS12/MIND complex 3
Path 2
Term Annotations click to browse term
  cellular_component 20118
    cellular anatomical entity 19774
      organelle 12828
        non-membrane-bounded organelle 4739
          intracellular non-membrane-bounded organelle 4720
            chromosome 1129
              chromosomal region 294
                chromosome, centromeric region 185
                  kinetochore 126
                    condensed chromosome kinetochore 64
                      condensed nuclear chromosome kinetochore 18
                        nuclear MIS12/MIND complex 3
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.