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ONTOLOGY REPORT - ANNOTATIONS


Term:transcription open complex formation at RNA polymerase II promoter
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Accession:GO:0001113 term browser browse the term
Definition:Any process involved in the melting of the DNA hybrid of the core promoter region within the transcriptional closed complex of an RNA polymerase II preinitiation complex (PIC) to produce an open complex where the DNA duplex around the transcription initiation site is unwound to form the transcription bubble.
Synonyms:exact_synonym: RNA polymerase II promoter melting;   transcriptional open complex formation at RNA polymerase II promoter


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transcription open complex formation at RNA polymerase II promoter term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gtf2e1 general transcription factor IIE subunit 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr11:66,078,786...66,111,394
Ensembl chr11:66,078,820...66,110,848
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  biological_process 20028
    cellular process 18800
      cellular component organization or biogenesis 6789
        cellular component organization 6534
          protein-containing complex subunit organization 1813
            protein-containing complex remodeling 29
              protein-DNA complex remodeling 2
                DNA-templated transcription open complex formation 2
                  transcription open complex formation at RNA polymerase II promoter 1
                    regulation of transcription open complex formation at RNA polymerase II promoter 0
Path 2
Term Annotations click to browse term
  biological_process 20028
    metabolic process 12271
      cellular metabolic process 11085
        cellular aromatic compound metabolic process 5715
          nucleobase-containing compound metabolic process 5489
            nucleic acid metabolic process 4985
              RNA metabolic process 4469
                RNA biosynthetic process 3477
                  nucleic acid-templated transcription 3463
                    transcription, DNA-templated 3418
                      DNA-templated transcription, initiation 124
                        DNA-templated transcription open complex formation 2
                          transcription open complex formation at RNA polymerase II promoter 1
                            regulation of transcription open complex formation at RNA polymerase II promoter 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.