ONTOLOGY REPORT - ANNOTATIONS


Term:action potential
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Accession:GO:0001508 term browser browse the term
Definition:A process in which membrane potential cycles through a depolarizing spike, triggered in response to depolarization above some threshold, followed by repolarization. This cycle is driven by the flow of ions through various voltage gated channels with different thresholds and ion specificities.
Comment:Action potentials typically propagate across excitable membranes. This class covers both action potentials that propagate and those that fail to do so.


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action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cacna1g calcium voltage-gated channel subunit alpha1 G JBrowse link 10 82,129,071 82,197,828 RGD:1624291
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit JBrowse link 3 176,533,182 176,547,965 RGD:1624291
RGD:1600115
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit JBrowse link 2 189,088,570 189,096,785 RGD:1624291
RGD:1600115
G Chrnb4 cholinergic receptor nicotinic beta 4 subunit JBrowse link 8 59,610,489 59,629,073 RGD:1624291
RGD:1600115
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin JBrowse link 1 197,986,384 197,999,726 RGD:1624291
RGD:1600115
G Gjd2 gap junction protein, delta 2 JBrowse link 3 105,467,480 105,470,475 RGD:1624291
RGD:1600115
G Glra1 glycine receptor, alpha 1 JBrowse link 10 40,851,955 40,954,364 RGD:1624291
RGD:1600115
G Gna11 G protein subunit alpha 11 JBrowse link 7 11,033,400 11,047,284 RGD:1624291
RGD:13792537
RGD:1600115
G Gnaq G protein subunit alpha q JBrowse link 1 233,382,778 233,622,584 RGD:1624291
RGD:13792537
RGD:1600115
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A JBrowse link 10 5,707,806 6,123,568 RGD:1642204
RGD:1642207
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B JBrowse link 4 169,541,620 170,000,216 RGD:1642204
RGD:1642207
G Kcnb1 potassium voltage-gated channel subfamily B member 1 JBrowse link 3 163,850,785 163,935,610 RGD:10047179
RGD:1600115
RGD:1624291
G Kcnc2 potassium voltage-gated channel subfamily C member 2 JBrowse link 7 54,978,453 55,159,362 RGD:1624291
G Kcnd2 potassium voltage-gated channel subfamily D member 2 JBrowse link 4 48,309,283 48,816,804 RGD:1581430
RGD:1624291
G Kcnmb2 potassium calcium-activated channel subfamily M regulatory beta subunit 2 JBrowse link 2 118,276,298 118,585,321 RGD:1624291
G Kcnmb3 potassium calcium-activated channel subfamily M regulatory beta subunit 3 JBrowse link 2 118,868,225 118,882,562 RGD:1624291
G Kcnmb4 potassium calcium-activated channel subfamily M regulatory beta subunit 4 JBrowse link 7 59,461,808 59,514,759 RGD:1624291
RGD:1600115
G Scn1a sodium voltage-gated channel alpha subunit 1 JBrowse link 3 52,388,811 52,533,365 RGD:1624291
G Usp53 ubiquitin specific peptidase 53 JBrowse link 2 227,098,795 227,160,385 RGD:1624291
atrial cardiac muscle cell action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ank2 ankyrin 2 JBrowse link 2 231,224,643 231,522,655 RGD:1624291
RGD:1600115
G Kcna5 potassium voltage-gated channel subfamily A member 5 JBrowse link 4 159,077,195 159,079,003 RGD:1624291
G Kcne5 potassium voltage-gated channel subfamily E regulatory subunit 5 JBrowse link X 113,583,844 113,584,459 RGD:1624291
RGD:1600115
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 JBrowse link 1 216,293,087 216,630,339 RGD:1624291
RGD:1600115
G Nup155 nucleoporin 155 JBrowse link 2 57,206,665 57,258,242 RGD:1624291
RGD:1600115
G Scn3b sodium voltage-gated channel beta subunit 3 JBrowse link 8 44,136,413 44,159,011 RGD:1624291
RGD:1600115
G Scn5a sodium voltage-gated channel alpha subunit 5 JBrowse link 8 128,169,191 128,266,681 RGD:1624291
RGD:1600115
AV node cell action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cacna1g calcium voltage-gated channel subunit alpha1 G JBrowse link 10 82,129,071 82,197,828 RGD:1624291
RGD:1600115
G Scn10a sodium voltage-gated channel alpha subunit 10 JBrowse link 8 128,298,593 128,416,896 RGD:1624291
RGD:13792537
G Scn4b sodium voltage-gated channel beta subunit 4 JBrowse link 8 49,441,106 49,456,279 RGD:1624291
RGD:1600115
G Scn5a sodium voltage-gated channel alpha subunit 5 JBrowse link 8 128,169,191 128,266,681 RGD:1624291
RGD:13792537
RGD:1600115
bundle of His cell action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Scn10a sodium voltage-gated channel alpha subunit 10 JBrowse link 8 128,298,593 128,416,896 RGD:1624291
RGD:1600115
G Scn5a sodium voltage-gated channel alpha subunit 5 JBrowse link 8 128,169,191 128,266,681 RGD:1624291
RGD:1600115
cardiac muscle cell action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dmd dystrophin JBrowse link X 51,149,358 53,519,271 RGD:1624291
RGD:1600115
G Kcnd2 potassium voltage-gated channel subfamily D member 2 JBrowse link 4 48,309,283 48,816,804 RGD:10047324
G Kcnj2 potassium voltage-gated channel subfamily J member 2 JBrowse link 10 99,429,337 99,442,520 RGD:1624291
G Pkp2 plakophilin 2 JBrowse link 11 88,912,163 88,972,213 RGD:6784504
cardiac muscle cell action potential involved in contraction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cacna1c calcium voltage-gated channel subunit alpha1 C JBrowse link 4 150,635,808 151,270,790 RGD:1624291
RGD:1600115
G Cacna1d calcium voltage-gated channel subunit alpha1 D JBrowse link 16 6,110,294 6,405,022 RGD:1600115
RGD:1624291
G Cacna1g calcium voltage-gated channel subunit alpha1 G JBrowse link 10 82,129,071 82,197,828 RGD:1600115
RGD:13792537
RGD:1624291
G Cacna2d1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 JBrowse link 4 15,706,974 16,130,848 RGD:1624291
RGD:1600115
G Kcne1 potassium voltage-gated channel subfamily E regulatory subunit 1 JBrowse link 11 32,498,260 32,511,202 RGD:1624291
G Kcne2 potassium voltage-gated channel subfamily E regulatory subunit 2 JBrowse link 11 32,434,786 32,447,264 RGD:1624291
G Kcnj2 potassium voltage-gated channel subfamily J member 2 JBrowse link 10 99,429,337 99,442,520 RGD:1624291
RGD:1600115
G Pkp2 plakophilin 2 JBrowse link 11 88,912,163 88,972,213 RGD:1624291
G Scn1a sodium voltage-gated channel alpha subunit 1 JBrowse link 3 52,388,811 52,533,365 RGD:1600115
RGD:1624291
G Scn1b sodium voltage-gated channel beta subunit 1 JBrowse link 1 89,550,738 89,560,469 RGD:1624291
RGD:13792537
G Scn2b sodium voltage-gated channel beta subunit 2 JBrowse link 8 49,419,003 49,431,110 RGD:1624291
RGD:1600115
G Scn3b sodium voltage-gated channel beta subunit 3 JBrowse link 8 44,136,413 44,159,011 RGD:1624291
RGD:13792537
G Scn4b sodium voltage-gated channel beta subunit 4 JBrowse link 8 49,441,106 49,456,279 RGD:1624291
RGD:1600115
G Scn5a sodium voltage-gated channel alpha subunit 5 JBrowse link 8 128,169,191 128,266,681 RGD:1624291
RGD:1600115
membrane depolarization during action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cacna1g calcium voltage-gated channel subunit alpha1 G JBrowse link 10 82,129,071 82,197,828 RGD:13792537
G Cacna1h calcium voltage-gated channel subunit alpha1 H JBrowse link 10 14,730,932 14,789,201 RGD:13792537
G Cacna1i calcium voltage-gated channel subunit alpha1 I JBrowse link 7 121,521,787 121,619,300 RGD:13792537
G Kcnh2 potassium voltage-gated channel subfamily H member 2 JBrowse link 4 7,355,066 7,387,282 RGD:1624291
RGD:1600115
G Scn10a sodium voltage-gated channel alpha subunit 10 JBrowse link 8 128,298,593 128,416,896 RGD:13792537
G Scn11a sodium voltage-gated channel alpha subunit 11 JBrowse link 8 128,450,793 128,527,510 RGD:13792537
G Scn1a sodium voltage-gated channel alpha subunit 1 JBrowse link 3 52,388,811 52,533,365 RGD:13792537
G Scn2a sodium voltage-gated channel alpha subunit 2 JBrowse link 3 51,687,910 51,822,008 RGD:13792537
G Scn3a sodium voltage-gated channel alpha subunit 3 JBrowse link 3 51,530,897 51,643,140 RGD:13792537
G Scn3b sodium voltage-gated channel beta subunit 3 JBrowse link 8 44,136,413 44,159,011 RGD:1624291
G Scn4a sodium voltage-gated channel alpha subunit 4 JBrowse link 10 94,505,026 94,557,803 RGD:13792537
G Scn5a sodium voltage-gated channel alpha subunit 5 JBrowse link 8 128,169,191 128,266,681 RGD:1600115
RGD:13792537
RGD:1624291
G Scn7a sodium voltage-gated channel alpha subunit 7 JBrowse link 3 52,775,779 52,877,365 RGD:13792537
G Scn8a sodium voltage-gated channel alpha subunit 8 JBrowse link 7 142,575,629 142,683,659 RGD:13792537
G Scn9a sodium voltage-gated channel alpha subunit 9 JBrowse link 3 52,583,953 52,664,209 RGD:13792537
G Ywhah tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta JBrowse link 14 83,053,041 83,062,424 RGD:1624291
RGD:1600115
membrane depolarization during atrial cardiac muscle cell action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cacna1c calcium voltage-gated channel subunit alpha1 C JBrowse link 4 150,635,808 151,270,790 RGD:1624291
RGD:1600115
G Cacnb2 calcium voltage-gated channel auxiliary subunit beta 2 JBrowse link 17 81,673,862 82,019,219 RGD:1624291
RGD:1600115
G Scn5a sodium voltage-gated channel alpha subunit 5 JBrowse link 8 128,169,191 128,266,681 RGD:1624291
membrane depolarization during AV node cell action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cacna1c calcium voltage-gated channel subunit alpha1 C JBrowse link 4 150,635,808 151,270,790 RGD:1624291
RGD:1600115
G Cacna1g calcium voltage-gated channel subunit alpha1 G JBrowse link 10 82,129,071 82,197,828 RGD:1624291
RGD:1600115
G Cacnb2 calcium voltage-gated channel auxiliary subunit beta 2 JBrowse link 17 81,673,862 82,019,219 RGD:1624291
RGD:1600115
G Scn5a sodium voltage-gated channel alpha subunit 5 JBrowse link 8 128,169,191 128,266,681 RGD:1624291
RGD:1600115
G Trpm4 transient receptor potential cation channel, subfamily M, member 4 JBrowse link 1 101,293,300 101,323,484 RGD:1600115
RGD:1624291
membrane depolarization during bundle of His cell action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cacna2d1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 JBrowse link 4 15,706,974 16,130,848 RGD:1600115
RGD:1624291
G Scn5a sodium voltage-gated channel alpha subunit 5 JBrowse link 8 128,169,191 128,266,681 RGD:1624291
RGD:1600115
G Trpm4 transient receptor potential cation channel, subfamily M, member 4 JBrowse link 1 101,293,300 101,323,484 RGD:1600115
RGD:1624291
membrane depolarization during cardiac muscle cell action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cacna1c calcium voltage-gated channel subunit alpha1 C JBrowse link 4 150,635,808 151,270,790 RGD:1624291
RGD:1600115
G Cacna1d calcium voltage-gated channel subunit alpha1 D JBrowse link 16 6,110,294 6,405,022 RGD:6767284
G Scn1b sodium voltage-gated channel beta subunit 1 JBrowse link 1 89,550,738 89,560,469 RGD:1624291
G Scn2b sodium voltage-gated channel beta subunit 2 JBrowse link 8 49,419,003 49,431,110 RGD:1624291
RGD:1600115
G Scn3b sodium voltage-gated channel beta subunit 3 JBrowse link 8 44,136,413 44,159,011 RGD:1624291
RGD:1600115
G Scn4b sodium voltage-gated channel beta subunit 4 JBrowse link 8 49,441,106 49,456,279 RGD:1624291
RGD:1600115
G Scn5a sodium voltage-gated channel alpha subunit 5 JBrowse link 8 128,169,191 128,266,681 RGD:1624291
RGD:1600115
membrane depolarization during Purkinje myocyte cell action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Scn1b sodium voltage-gated channel beta subunit 1 JBrowse link 1 89,550,738 89,560,469 RGD:1624291
RGD:1600115
G Scn5a sodium voltage-gated channel alpha subunit 5 JBrowse link 8 128,169,191 128,266,681 RGD:1624291
RGD:1600115
G Trpm4 transient receptor potential cation channel, subfamily M, member 4 JBrowse link 1 101,293,300 101,323,484 RGD:1600115
RGD:1624291
membrane depolarization during SA node cell action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cacna1d calcium voltage-gated channel subunit alpha1 D JBrowse link 16 6,110,294 6,405,022 RGD:1624291
RGD:1600115
G Cacna1g calcium voltage-gated channel subunit alpha1 G JBrowse link 10 82,129,071 82,197,828 RGD:1624291
RGD:1600115
G Hcn4 hyperpolarization activated cyclic nucleotide-gated potassium channel 4 JBrowse link 8 63,599,907 63,637,327 RGD:1600115
RGD:1624291
G Scn5a sodium voltage-gated channel alpha subunit 5 JBrowse link 8 128,169,191 128,266,681 RGD:1624291
RGD:1600115
membrane repolarization during action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Kcne1 potassium voltage-gated channel subfamily E regulatory subunit 1 JBrowse link 11 32,498,260 32,511,202 RGD:1624291
RGD:13792537
G Kcne2 potassium voltage-gated channel subfamily E regulatory subunit 2 JBrowse link 11 32,434,786 32,447,264 RGD:1624291
RGD:13792537
RGD:633041
G Kcne3 potassium voltage-gated channel subfamily E regulatory subunit 3 JBrowse link 1 165,189,934 165,196,949 RGD:13792537
G Kcne4 potassium voltage-gated channel subfamily E regulatory subunit 4 JBrowse link 9 84,688,873 84,693,066 RGD:13792537
G Kcne5 potassium voltage-gated channel subfamily E regulatory subunit 5 JBrowse link X 113,583,844 113,584,459 RGD:13792537
G Kcnh2 potassium voltage-gated channel subfamily H member 2 JBrowse link 4 7,355,066 7,387,282 RGD:1624291
G Kcnj2 potassium voltage-gated channel subfamily J member 2 JBrowse link 10 99,429,337 99,442,520 RGD:1624291
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 JBrowse link 1 216,293,087 216,630,339 RGD:1624291
membrane repolarization during atrial cardiac muscle cell action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Kcna5 potassium voltage-gated channel subfamily A member 5 JBrowse link 4 159,077,195 159,079,003 RGD:1624291
RGD:1600115
G Kcnj5 potassium voltage-gated channel subfamily J member 5 JBrowse link 8 33,435,493 33,463,410 RGD:1624291
RGD:1600115
G Kcnn2 potassium calcium-activated channel subfamily N member 2 JBrowse link 18 39,331,894 39,479,574 RGD:1624291
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 JBrowse link 1 216,293,087 216,630,339 RGD:1600115
RGD:1624291
membrane repolarization during bundle of His cell action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Kcna5 potassium voltage-gated channel subfamily A member 5 JBrowse link 4 159,077,195 159,079,003 RGD:1624291
RGD:1600115
membrane repolarization during cardiac muscle cell action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Kcne1 potassium voltage-gated channel subfamily E regulatory subunit 1 JBrowse link 11 32,498,260 32,511,202 RGD:1624291
G Kcnh2 potassium voltage-gated channel subfamily H member 2 JBrowse link 4 7,355,066 7,387,282 RGD:1624291
G Kcnj2 potassium voltage-gated channel subfamily J member 2 JBrowse link 10 99,429,337 99,442,520 RGD:1624291
RGD:1600115
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 JBrowse link 1 216,293,087 216,630,339 RGD:1624291
membrane repolarization during SA node cell action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Kcna5 potassium voltage-gated channel subfamily A member 5 JBrowse link 4 159,077,195 159,079,003 RGD:1600115
RGD:1624291
membrane repolarization during ventricular cardiac muscle cell action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Kcnd3 potassium voltage-gated channel subfamily D member 3 JBrowse link 2 207,923,775 208,140,727 RGD:1600115
G Kcne1 potassium voltage-gated channel subfamily E regulatory subunit 1 JBrowse link 11 32,498,260 32,511,202 RGD:1624291
G Kcne2 potassium voltage-gated channel subfamily E regulatory subunit 2 JBrowse link 11 32,434,786 32,447,264 RGD:1624291
RGD:1600115
G Kcne3 potassium voltage-gated channel subfamily E regulatory subunit 3 JBrowse link 1 165,189,934 165,196,949 RGD:1600115
G Kcne4 potassium voltage-gated channel subfamily E regulatory subunit 4 JBrowse link 9 84,688,873 84,693,066 RGD:1600115
G Kcne5 potassium voltage-gated channel subfamily E regulatory subunit 5 JBrowse link X 113,583,844 113,584,459 RGD:1600115
G Kcnh2 potassium voltage-gated channel subfamily H member 2 JBrowse link 4 7,355,066 7,387,282 RGD:1624291
RGD:1600115
G Kcnj8 potassium voltage-gated channel subfamily J member 8 JBrowse link 4 176,783,287 176,789,143 RGD:1624291
RGD:1600115
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 JBrowse link 1 216,293,087 216,630,339 RGD:1624291
RGD:1600115
negative regulation of action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit JBrowse link 2 189,088,570 189,096,785 RGD:1624291
RGD:1600115
G Cnr1 cannabinoid receptor 1 JBrowse link 5 49,307,584 49,333,064 RGD:2316187
G Cnr2 cannabinoid receptor 2 JBrowse link 5 154,242,010 154,268,126 RGD:2316192
G Hcn1 hyperpolarization-activated cyclic nucleotide-gated potassium channel 1 JBrowse link 2 50,099,576 50,499,799 RGD:9686419
G Sumo1 small ubiquitin-like modifier 1 JBrowse link 9 66,453,428 66,483,614 RGD:1624291
RGD:1600115
negative regulation of membrane depolarization during cardiac muscle cell action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cav3 caveolin 3 JBrowse link 4 144,382,945 144,398,919 RGD:1624291
RGD:1600115
negative regulation of membrane repolarization during ventricular cardiac muscle cell action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Kcne3 potassium voltage-gated channel subfamily E regulatory subunit 3 JBrowse link 1 165,189,934 165,196,949 RGD:1624291
RGD:1600115
negative regulation of neuronal action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gpr35 G protein-coupled receptor 35 JBrowse link 9 100,129,428 100,141,269 RGD:11541107
G Kcnc4 potassium voltage-gated channel subfamily C member 4 JBrowse link 2 210,220,908 210,241,447 RGD:10412022
negative regulation of ventricular cardiac muscle cell action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bin1 bridging integrator 1 JBrowse link 18 25,163,575 25,222,139 RGD:1600115
RGD:1624291
neuronal action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ank3 ankyrin 3 JBrowse link 20 19,948,767 20,480,628 RGD:1624291
G Cacna1g calcium voltage-gated channel subunit alpha1 G JBrowse link 10 82,129,071 82,197,828 RGD:13792537
G Cacna1h calcium voltage-gated channel subunit alpha1 H JBrowse link 10 14,730,932 14,789,201 RGD:13792537
G Cacna1i calcium voltage-gated channel subunit alpha1 I JBrowse link 7 121,521,787 121,619,300 RGD:1624291
RGD:13792537
G Chrna1 cholinergic receptor nicotinic alpha 1 subunit JBrowse link 3 60,445,657 60,460,724 RGD:1624291
RGD:1600115
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit JBrowse link 1 123,897,341 124,039,263 RGD:1600975
RGD:1642691
G Dpp6 dipeptidyl peptidase like 6 JBrowse link 4 4,021,021 4,943,675 RGD:1624291
G Drd1 dopamine receptor D1 JBrowse link 17 11,099,736 11,104,352 RGD:1624291
RGD:1600115
G Gper1 G protein-coupled estrogen receptor 1 JBrowse link 12 17,309,122 17,315,267 RGD:1600115
G Gpr88 G-protein coupled receptor 88 JBrowse link 2 219,258,346 219,263,819 RGD:1624291
RGD:1600115
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 JBrowse link 10 42,441,723 42,760,200 RGD:8553676
G Grik2 glutamate ionotropic receptor kainate type subunit 2 JBrowse link 20 53,791,428 54,517,691 RGD:1624291
RGD:1600115
G Kcna1 potassium voltage-gated channel subfamily A member 1 JBrowse link 4 159,190,781 159,192,526 RGD:10047355
RGD:1600115
RGD:1624291
RGD:10047215
G Kcna2 potassium voltage-gated channel subfamily A member 2 JBrowse link 2 209,838,607 209,852,471 RGD:10047355
G Kcnd2 potassium voltage-gated channel subfamily D member 2 JBrowse link 4 48,309,283 48,816,804 RGD:1624291
G Kcnma1 potassium calcium-activated channel subfamily M alpha 1 JBrowse link 15 344,204 1,048,849 RGD:1624291
G Kcnmb2 potassium calcium-activated channel subfamily M regulatory beta subunit 2 JBrowse link 2 118,276,298 118,585,321 RGD:1624291
G Kcnmb3 potassium calcium-activated channel subfamily M regulatory beta subunit 3 JBrowse link 2 118,868,225 118,882,562 RGD:1624291
RGD:1600115
G Kcnmb4 potassium calcium-activated channel subfamily M regulatory beta subunit 4 JBrowse link 7 59,461,808 59,514,759 RGD:1624291
RGD:1600115
G Myh14 myosin heavy chain 14 JBrowse link 1 100,608,975 100,671,086 RGD:1624291
RGD:1600115
G P2rx1 purinergic receptor P2X 1 JBrowse link 10 59,566,268 59,581,328 RGD:1642659
RGD:727431
G P2rx2 purinergic receptor P2X 2 JBrowse link 12 52,397,666 52,401,005 RGD:1642659
RGD:1642666
RGD:1642665
RGD:1642662
G P2rx3 purinergic receptor P2X 3 JBrowse link 3 72,403,992 72,447,801 RGD:1642659
RGD:1642675
G P2rx4 purinergic receptor P2X 4 JBrowse link 12 39,308,022 39,325,673 RGD:1642659
RGD:1642695
RGD:1642691
G P2rx5 purinergic receptor P2X 5 JBrowse link 10 59,725,438 59,737,126 RGD:727431
G P2rx7 purinergic receptor P2X 7 JBrowse link 12 39,353,613 39,396,042 RGD:1642698
G Pmp22 peripheral myelin protein 22 JBrowse link 10 49,538,588 49,568,583 RGD:1624291
G Scn10a sodium voltage-gated channel alpha subunit 10 JBrowse link 8 128,298,593 128,416,896 RGD:13792537
G Scn11a sodium voltage-gated channel alpha subunit 11 JBrowse link 8 128,450,793 128,527,510 RGD:13792537
G Scn1a sodium voltage-gated channel alpha subunit 1 JBrowse link 3 52,388,811 52,533,365 RGD:68844
RGD:13792537
RGD:1624291
RGD:1600115
RGD:2289022
RGD:2289019
RGD:1599536
G Scn2a sodium voltage-gated channel alpha subunit 2 JBrowse link 3 51,687,910 51,822,008 RGD:68844
RGD:13792537
RGD:2289019
RGD:1599536
G Scn3a sodium voltage-gated channel alpha subunit 3 JBrowse link 3 51,530,897 51,643,140 RGD:1599536
RGD:13792537
G Scn4a sodium voltage-gated channel alpha subunit 4 JBrowse link 10 94,505,026 94,557,803 RGD:13792537
G Scn5a sodium voltage-gated channel alpha subunit 5 JBrowse link 8 128,169,191 128,266,681 RGD:13792537
G Scn7a sodium voltage-gated channel alpha subunit 7 JBrowse link 3 52,775,779 52,877,365 RGD:13792537
G Scn8a sodium voltage-gated channel alpha subunit 8 JBrowse link 7 142,575,629 142,683,659 RGD:1599536
RGD:13792537
RGD:2289022
RGD:2289019
G Scn9a sodium voltage-gated channel alpha subunit 9 JBrowse link 3 52,583,953 52,664,209 RGD:1599536
RGD:13792537
neuronal action potential propagation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cacnb4 calcium voltage-gated channel auxiliary subunit beta 4 JBrowse link 3 37,950,846 38,211,478 RGD:1624291
RGD:1600115
G Clcn1 chloride voltage-gated channel 1 JBrowse link 4 71,674,218 71,704,318 RGD:1624291
RGD:1600115
G Cldn19 claudin 19 JBrowse link 5 138,300,692 138,307,982 RGD:1624291
RGD:1600115
G Cntnap1 contactin associated protein 1 JBrowse link 10 89,087,904 89,103,615 RGD:1624291
RGD:1600115
G Fkbp1b FKBP prolyl isomerase 1B JBrowse link 6 29,975,863 29,987,252 RGD:1624291
RGD:1600115
G Nrcam neuronal cell adhesion molecule JBrowse link 6 64,297,843 64,867,408 RGD:1624291
RGD:1600115
G Ntrk2 neurotrophic receptor tyrosine kinase 2 JBrowse link 17 5,934,651 6,245,778 RGD:1624291
RGD:1600115
G Ntrk3 neurotrophic receptor tyrosine kinase 3 JBrowse link 1 139,890,537 140,262,503 RGD:1624291
RGD:1600115
G Pmp22 peripheral myelin protein 22 JBrowse link 10 49,538,588 49,568,583 RGD:1624291
G Scn1a sodium voltage-gated channel alpha subunit 1 JBrowse link 3 52,388,811 52,533,365 RGD:1624291
RGD:1600115
G Scn1b sodium voltage-gated channel beta subunit 1 JBrowse link 1 89,550,738 89,560,469 RGD:1624291
RGD:1600115
positive regulation of action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adra1a adrenoceptor alpha 1A JBrowse link 15 43,296,997 43,398,314 RGD:1625774
G Ffar3 free fatty acid receptor 3 JBrowse link 1 89,302,035 89,304,064 RGD:1624291
RGD:1600115
G Hnrnpa1 heterogeneous nuclear ribonucleoprotein A1 JBrowse link 7 144,865,302 144,871,592 RGD:10045966
G Kcnip1 potassium voltage-gated channel interacting protein 1 JBrowse link 10 18,558,128 18,942,677 RGD:1581450
G Nps neuropeptide S JBrowse link 1 207,508,414 207,512,195 RGD:1624291
RGD:13792537
G Pawr pro-apoptotic WT1 regulator JBrowse link 7 51,273,764 51,353,700 RGD:9835398
G Scn5a sodium voltage-gated channel alpha subunit 5 JBrowse link 8 128,169,191 128,266,681 RGD:6484222
G Slc9a1 solute carrier family 9 member A1 JBrowse link 5 151,573,122 151,626,360 RGD:6771338
G Tac1 tachykinin, precursor 1 JBrowse link 4 33,638,853 33,646,819 RGD:2304273
RGD:2304326
G Tacr1 tachykinin receptor 1 JBrowse link 4 113,247,236 113,416,139 RGD:2304273
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:7421501
positive regulation of atrial cardiac muscle cell action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Trpm4 transient receptor potential cation channel, subfamily M, member 4 JBrowse link 1 101,293,300 101,323,484 RGD:10003031
positive regulation of membrane depolarization during cardiac muscle cell action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ank3 ankyrin 3 JBrowse link 20 19,948,767 20,480,628 RGD:6767295
positive regulation of neuronal action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gba glucosylceramidase beta JBrowse link 2 188,511,781 188,522,602 RGD:1624291
RGD:1600115
G Oprk1 opioid receptor, kappa 1 JBrowse link 5 13,742,655 13,760,460 RGD:1624291
G Pawr pro-apoptotic WT1 regulator JBrowse link 7 51,273,764 51,353,700 RGD:9835339
G Rapgef4 Rap guanine nucleotide exchange factor 4 JBrowse link 3 58,632,338 58,925,127 RGD:9850100
positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Rnf207 ring finger protein 207 JBrowse link 5 169,486,253 169,500,451 RGD:1624291
RGD:1600115
regulation of action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd36 CD36 molecule JBrowse link 4 14,150,309 14,191,498 RGD:1624291
G Foxp1 forkhead box P1 JBrowse link 4 131,362,178 131,963,466 RGD:1600115
RGD:1624291
G Kcnb1 potassium voltage-gated channel subfamily B member 1 JBrowse link 3 163,850,785 163,935,610 RGD:1600115
RGD:1624291
G Ntsr1 neurotensin receptor 1 JBrowse link 3 175,982,313 176,046,345 RGD:9743976
regulation of atrial cardiac muscle cell action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ank2 ankyrin 2 JBrowse link 2 231,224,643 231,522,655 RGD:1624291
RGD:1600115
G Gja5 gap junction protein, alpha 5 JBrowse link 2 199,162,745 199,184,942 RGD:1624291
RGD:1600115
G Ryr2 ryanodine receptor 2 JBrowse link 17 65,533,998 65,955,606 RGD:1624291
RGD:1600115
regulation of AV node cell action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ank2 ankyrin 2 JBrowse link 2 231,224,643 231,522,655 RGD:1624291
G Cxadr CXADR, Ig-like cell adhesion molecule JBrowse link 11 16,826,269 16,873,564 RGD:1624291
RGD:1600115
G Gja5 gap junction protein, alpha 5 JBrowse link 2 199,162,745 199,184,942 RGD:1624291
RGD:1600115
G Ryr2 ryanodine receptor 2 JBrowse link 17 65,533,998 65,955,606 RGD:1624291
RGD:1600115
regulation of bundle of His cell action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gja5 gap junction protein, alpha 5 JBrowse link 2 199,162,745 199,184,942 RGD:1624291
RGD:1600115
G Rangrf RAN guanine nucleotide release factor JBrowse link 10 55,559,049 55,560,420 RGD:1624291
RGD:1600115
regulation of cardiac muscle cell action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Camk2d calcium/calmodulin-dependent protein kinase II delta JBrowse link 2 230,900,907 231,132,207 RGD:10047271
G Nos1ap nitric oxide synthase 1 adaptor protein JBrowse link 13 88,653,123 88,943,976 RGD:10047296
regulation of cardiac muscle cell action potential involved in regulation of contraction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akap9 A-kinase anchoring protein 9 JBrowse link 4 27,195,346 27,331,582 RGD:1624291
RGD:1600115
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 JBrowse link 12 39,553,903 39,603,326 RGD:10047146
G Camk2d calcium/calmodulin-dependent protein kinase II delta JBrowse link 2 230,900,907 231,132,207 RGD:10047271
G Cav3 caveolin 3 JBrowse link 4 144,382,945 144,398,919 RGD:1624291
RGD:1600115
G Fgf13 fibroblast growth factor 13 JBrowse link X 142,053,648 142,589,274 RGD:1624291
RGD:1600115
G Hcn4 hyperpolarization activated cyclic nucleotide-gated potassium channel 4 JBrowse link 8 63,599,907 63,637,327 RGD:1600115
RGD:1624291
G Rangrf RAN guanine nucleotide release factor JBrowse link 10 55,559,049 55,560,420 RGD:1624291
RGD:1600115
regulation of membrane depolarization during action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ptpn3 protein tyrosine phosphatase, non-receptor type 3 JBrowse link 5 74,248,996 74,368,167 RGD:1624291
RGD:1600115
regulation of membrane depolarization during cardiac muscle cell action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cav3 caveolin 3 JBrowse link 4 144,382,945 144,398,919 RGD:1624291
RGD:13792537
G Gja5 gap junction protein, alpha 5 JBrowse link 2 199,162,745 199,184,942 RGD:1624291
RGD:1600115
G Rangrf RAN guanine nucleotide release factor JBrowse link 10 55,559,049 55,560,420 RGD:1624291
RGD:1600115
G Slmap sarcolemma associated protein JBrowse link 16 2,112,271 2,227,336 RGD:1600115
RGD:1624291
regulation of membrane repolarization during action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cacna2d1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 JBrowse link 4 15,706,974 16,130,848 RGD:11059598
G Cacnb3 calcium voltage-gated channel auxiliary subunit beta 3 JBrowse link 7 140,311,120 140,324,902 RGD:11059598
G Cav1 caveolin 1 JBrowse link 4 44,597,123 44,630,206 RGD:1624291
RGD:1600115
regulation of membrane repolarization during cardiac muscle cell action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Flna filamin A JBrowse link X 156,460,785 156,487,245 RGD:1624291
regulation of neuronal action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fgf12 fibroblast growth factor 12 JBrowse link 11 75,606,360 76,171,078 RGD:1624291
RGD:1600115
G Fmr1 fragile X mental retardation 1 JBrowse link X 154,684,924 154,722,369 RGD:1600115
RGD:1624291
G Ifng interferon gamma JBrowse link 7 61,337,383 61,341,419 RGD:8158038
G Mtnr1b melatonin receptor 1B JBrowse link 8 14,359,270 14,373,894 RGD:9588677
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 JBrowse link 5 3,783,247 3,836,485 RGD:10043789
regulation of Purkinje myocyte action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gja5 gap junction protein, alpha 5 JBrowse link 2 199,162,745 199,184,942 RGD:1624291
RGD:1600115
regulation of SA node cell action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ank2 ankyrin 2 JBrowse link 2 231,224,643 231,522,655 RGD:1624291
RGD:1600115
G Ryr2 ryanodine receptor 2 JBrowse link 17 65,533,998 65,955,606 RGD:1624291
RGD:1600115
regulation of skeletal muscle contraction by action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Scn4a sodium voltage-gated channel alpha subunit 4 JBrowse link 10 94,505,026 94,557,803 RGD:1600115
RGD:1624291
regulation of skeletal muscle contraction via regulation of action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Kcnj2 potassium voltage-gated channel subfamily J member 2 JBrowse link 10 99,429,337 99,442,520 RGD:1624291
RGD:1600115
regulation of ventricular cardiac muscle cell action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cacna1c calcium voltage-gated channel subunit alpha1 C JBrowse link 4 150,635,808 151,270,790 RGD:1600115
RGD:1624291
G Cav1 caveolin 1 JBrowse link 4 44,597,123 44,630,206 RGD:1624291
RGD:1600115
G Ctnna3 catenin alpha 3 JBrowse link 20 25,063,124 26,640,428 RGD:1624291
G Dlg1 discs large MAGUK scaffold protein 1 JBrowse link 11 72,164,566 72,378,895 RGD:1624291
G Dsc2 desmocollin 2 JBrowse link 18 11,826,705 11,858,801 RGD:1624291
RGD:1600115
G Dsg2 desmoglein 2 JBrowse link 18 15,579,322 15,637,720 RGD:1624291
RGD:1600115
G Dsp desmoplakin JBrowse link 17 27,286,811 27,334,453 RGD:1624291
RGD:1600115
G Jup junction plakoglobin JBrowse link 10 88,280,517 88,307,451 RGD:1624291
RGD:1600115
G Pkp2 plakophilin 2 JBrowse link 11 88,912,163 88,972,213 RGD:1624291
G Ryr2 ryanodine receptor 2 JBrowse link 17 65,533,998 65,955,606 RGD:1624291
RGD:1600115
G Trpm4 transient receptor potential cation channel, subfamily M, member 4 JBrowse link 1 101,293,300 101,323,484 RGD:1600115
RGD:1624291
regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dlg1 discs large MAGUK scaffold protein 1 JBrowse link 11 72,164,566 72,378,895 RGD:1600115
RGD:1624291
SA node cell action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ank2 ankyrin 2 JBrowse link 2 231,224,643 231,522,655 RGD:1624291
G Cacna1g calcium voltage-gated channel subunit alpha1 G JBrowse link 10 82,129,071 82,197,828 RGD:1624291
RGD:1600115
G Gja5 gap junction protein, alpha 5 JBrowse link 2 199,162,745 199,184,942 RGD:1624291
RGD:1600115
G Hcn4 hyperpolarization activated cyclic nucleotide-gated potassium channel 4 JBrowse link 8 63,599,907 63,637,327 RGD:1624291
G Scn3b sodium voltage-gated channel beta subunit 3 JBrowse link 8 44,136,413 44,159,011 RGD:1624291
RGD:1600115
G Scn5a sodium voltage-gated channel alpha subunit 5 JBrowse link 8 128,169,191 128,266,681 RGD:1624291
RGD:1600115
ventricular cardiac muscle cell action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ank2 ankyrin 2 JBrowse link 2 231,224,643 231,522,655 RGD:1624291
RGD:1600115
G Cav3 caveolin 3 JBrowse link 4 144,382,945 144,398,919 RGD:8553349
G Gja5 gap junction protein, alpha 5 JBrowse link 2 199,162,745 199,184,942 RGD:1624291
RGD:1600115
G Gpd1l glycerol-3-phosphate dehydrogenase 1-like JBrowse link 8 122,957,570 122,987,236 RGD:1624291
RGD:1600115
G Kcne1 potassium voltage-gated channel subfamily E regulatory subunit 1 JBrowse link 11 32,498,260 32,511,202 RGD:1624291
RGD:13792537
G Kcne2 potassium voltage-gated channel subfamily E regulatory subunit 2 JBrowse link 11 32,434,786 32,447,264 RGD:1624291
RGD:13792537
G Kcne3 potassium voltage-gated channel subfamily E regulatory subunit 3 JBrowse link 1 165,189,934 165,196,949 RGD:13792537
G Kcne4 potassium voltage-gated channel subfamily E regulatory subunit 4 JBrowse link 9 84,688,873 84,693,066 RGD:13792537
G Kcne5 potassium voltage-gated channel subfamily E regulatory subunit 5 JBrowse link X 113,583,844 113,584,459 RGD:1624291
RGD:13792537
G Kcnh2 potassium voltage-gated channel subfamily H member 2 JBrowse link 4 7,355,066 7,387,282 RGD:1624291
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 JBrowse link 1 216,293,087 216,630,339 RGD:1624291
G Nedd4l neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase JBrowse link 18 60,392,376 60,719,720 RGD:8553349
G Pkp2 plakophilin 2 JBrowse link 11 88,912,163 88,972,213 RGD:1624291
G Ryr2 ryanodine receptor 2 JBrowse link 17 65,533,998 65,955,606 RGD:1624291
RGD:1600115
G Scn3b sodium voltage-gated channel beta subunit 3 JBrowse link 8 44,136,413 44,159,011 RGD:1624291
RGD:13792537
G Scn5a sodium voltage-gated channel alpha subunit 5 JBrowse link 8 128,169,191 128,266,681 RGD:1624291
G Snta1 syntrophin, alpha 1 JBrowse link 3 149,874,023 149,905,980 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17896
    biological regulation 12607
      regulation of biological quality 4125
        regulation of membrane potential 466
          action potential 139
            action potential initiation 0
            action potential propagation + 11
            cardiac muscle cell action potential + 57
            membrane depolarization during action potential + 31
            membrane repolarization during action potential + 19
            negative regulation of action potential + 10
            neuronal action potential + 48
            positive regulation of action potential + 17
            regulation of action potential + 62
            regulation of skeletal muscle contraction by action potential + 2
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.