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ONTOLOGY REPORT - ANNOTATIONS


Term:luteolysis
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Accession:GO:0001554 term browser browse the term
Definition:The lysis or structural demise of the corpus luteum. During normal luteolysis, two closely related events occur. First, there is loss of the capacity to synthesize and secrete progesterone (functional luteolysis) followed by loss of the cells that comprise the corpus luteum (structural luteolysis). Preventing luteolysis is crucial to maintain pregnancy.
Synonyms:xref: Wikipedia:Luteolysis


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luteolysis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Casp12 caspase 12 JBrowse link 8 2,658,892 2,686,160 RGD:13782179
G Casp2 caspase 2 JBrowse link 4 71,652,358 71,670,228 RGD:4107077
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:13782179
G Ddit3 DNA-damage inducible transcript 3 JBrowse link 7 70,578,564 70,585,074 RGD:13782179
G Hspa5 heat shock protein family A (Hsp70) member 5 JBrowse link 3 13,838,304 13,842,763 RGD:13782179
G Mmp1 matrix metallopeptidase 1 JBrowse link 8 5,703,206 5,723,593 RGD:7207087
G Mmp13 matrix metallopeptidase 13 JBrowse link 8 5,522,739 5,533,018 RGD:7207086
G Mmp19 matrix metallopeptidase 19 JBrowse link 7 3,216,392 3,224,202 RGD:1642024
G Pla2g4a phospholipase A2 group IVA JBrowse link 13 67,062,252 67,206,688 RGD:1642472
apoptotic process involved in luteolysis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Robo2 roundabout guidance receptor 2 JBrowse link 11 11,062,866 12,618,793 RGD:1624291
RGD:1600115
G Slit2 slit guidance ligand 2 JBrowse link 14 66,831,848 67,171,491 RGD:1600115
RGD:1624291
G Slit3 slit guidance ligand 3 JBrowse link 10 19,924,200 20,517,918 RGD:1600115
RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18166
    reproductive process 1682
      ovulation cycle process 76
        luteolysis 12
          apoptotic process involved in luteolysis 3
          negative regulation of progesterone biosynthesis involved in luteolysis 0
Path 2
Term Annotations click to browse term
  biological_process 18166
    developmental process 6539
      anatomical structure development 6020
        multicellular organism development 5501
          system development 5050
            reproductive system development 574
              reproductive structure development 569
                gonad development 313
                  female gonad development 153
                    luteolysis 12
                      apoptotic process involved in luteolysis 3
                      negative regulation of progesterone biosynthesis involved in luteolysis 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.