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ONTOLOGY REPORT - ANNOTATIONS


Term:luteolysis
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Accession:GO:0001554 term browser browse the term
Definition:The lysis or structural demise of the corpus luteum. During normal luteolysis, two closely related events occur. First, there is loss of the capacity to synthesize and secrete progesterone (functional luteolysis) followed by loss of the cells that comprise the corpus luteum (structural luteolysis). Preventing luteolysis is crucial to maintain pregnancy.
Synonyms:xref: Wikipedia:Luteolysis


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luteolysis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp12 caspase 12 IEP RGD PMID:25332219 RGD:13782179 NCBI chr 8:2,658,892...2,686,160
Ensembl chr 8:2,659,865...2,686,160
JBrowse link
G Casp2 caspase 2 IEP RGD PMID:16940287 RGD:4107077 NCBI chr 4:71,652,358...71,670,228
Ensembl chr 4:71,652,354...71,670,239
JBrowse link
G Casp3 caspase 3 IEP RGD PMID:25332219 RGD:13782179 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 IEP RGD PMID:25332219 RGD:13782179 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 IEP RGD PMID:25332219 RGD:13782179 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
JBrowse link
G Mmp1 matrix metallopeptidase 1 IEP RGD PMID:8835383 RGD:7207087 NCBI chr 8:5,703,206...5,723,593
Ensembl chr 8:5,703,206...5,723,591
JBrowse link
G Mmp13 matrix metallopeptidase 13 IEP RGD PMID:10537164 RGD:7207086 NCBI chr 8:5,522,739...5,533,018
Ensembl chr 8:5,522,739...5,533,018
JBrowse link
G Mmp19 matrix metallopeptidase 19 IEP RGD PMID:15286033 RGD:1642024 NCBI chr 7:3,216,392...3,224,202
Ensembl chr 7:3,216,497...3,224,201
JBrowse link
G Pla2g4a phospholipase A2 group IVA IEP RGD PMID:11444430 RGD:1642472 NCBI chr13:67,062,252...67,206,688
Ensembl chr13:66,988,937...67,206,693
JBrowse link
apoptotic process involved in luteolysis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Robo2 roundabout guidance receptor 2 ISO (PMID:18566128) RGD PMID:18566128 NCBI chr11:11,062,866...12,618,793
Ensembl chr11:11,062,790...11,585,765
JBrowse link
G Slit2 slit guidance ligand 2 IEA
ISO
GO_REF:0000107
(PMID:18566128)
Ensembl
RGD
PMID:18566128 GO_REF:0000107 NCBI chr14:66,831,848...67,171,491
Ensembl chr14:66,831,848...67,170,361
JBrowse link
G Slit3 slit guidance ligand 3 IEA
ISO
GO_REF:0000107
(PMID:18566128)
Ensembl
RGD
PMID:18566128 GO_REF:0000107 NCBI chr10:19,924,200...20,517,918
Ensembl chr10:20,320,878...20,518,518
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20030
    reproductive process 1798
      ovulation cycle process 76
        luteolysis 12
          apoptotic process involved in luteolysis 3
          negative regulation of progesterone biosynthesis involved in luteolysis 0
Path 2
Term Annotations click to browse term
  biological_process 20030
    developmental process 6828
      anatomical structure development 6270
        multicellular organism development 5744
          system development 5280
            reproductive system development 593
              reproductive structure development 588
                gonad development 326
                  female gonad development 156
                    luteolysis 12
                      apoptotic process involved in luteolysis 3
                      negative regulation of progesterone biosynthesis involved in luteolysis 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.