Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:formation of primary germ layer
go back to main search page
Accession:GO:0001704 term browser browse the term
Definition:The formation of the ectoderm, mesoderm and endoderm during gastrulation.


show annotations for term's descendants           Sort by:
 
formation of primary germ layer term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARID1A AT-rich interaction domain 1A IEA Ensembl GO_REF:0000107 NCBI chr 1:26,696,015...26,782,104
Ensembl chr 1:26,693,236...26,782,104
JBrowse link
G ATOH8 atonal bHLH transcription factor 8 ISS UniProtKB GO_REF:0000024 NCBI chr 2:85,753,786...85,791,383
Ensembl chr 2:85,751,344...85,791,383
JBrowse link
G KIF16B kinesin family member 16B ISS UniProtKB GO_REF:0000024 NCBI chr20:16,272,104...16,573,457
Ensembl chr20:16,272,104...16,573,448
Ensembl chr20:16,272,104...16,573,448
JBrowse link
axial mesoderm formation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AXIN1 axin 1 ISO (MGI:894149|PMID:9230313) MGI PMID:9230313 MGI:894149 NCBI chr16:287,440...355,226
Ensembl chr16:287,440...352,723
JBrowse link
G EPHA2 EPH receptor A2 IEA Ensembl GO_REF:0000107 NCBI chr 1:16,124,337...16,156,104
Ensembl chr 1:16,124,337...16,156,069
JBrowse link
axial mesodermal cell fate specification term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NODAL nodal growth differentiation factor IEA Ensembl GO_REF:0000107 NCBI chr10:70,431,936...70,447,951
Ensembl chr10:70,431,936...70,447,951
JBrowse link
BMP signaling pathway involved in mesodermal cell fate specification term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ETV2 ETS variant transcription factor 2 IEA Ensembl GO_REF:0000107 NCBI chr19:35,641,175...35,644,871
Ensembl chr19:35,641,745...35,644,871
JBrowse link
cell fate commitment involved in formation of primary germ layer term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G POU5F1 POU class 5 homeobox 1 IMP (PMID:19736317) BHF-UCL PMID:19736317 NCBI chr 6:31,164,337...31,170,682
Ensembl chr 6:31,164,337...31,180,731
JBrowse link
ectoderm formation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FOXA2 forkhead box A2 ISO (MGI:1344734|PMID:10498685) MGI PMID:10498685 MGI:1344734 NCBI chr20:22,580,998...22,585,490
Ensembl chr20:22,581,005...22,585,455
JBrowse link
G LHX1 LIM homeobox 1 ISS UniProtKB GO_REF:0000024 NCBI chr17:36,937,475...36,944,612
Ensembl chr17:36,936,785...36,944,612
JBrowse link
ectodermal cell fate commitment term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ELF5 E74 like ETS transcription factor 5 IEA Ensembl GO_REF:0000107 NCBI chr11:34,478,791...34,513,794
Ensembl chr11:34,478,793...34,525,193
Ensembl chr11:34,478,793...34,525,193
Ensembl chr11:34,478,793...34,525,193
JBrowse link
G ETS2 ETS proto-oncogene 2, transcription factor IEA Ensembl GO_REF:0000107 NCBI chr21:38,805,183...38,824,955
Ensembl chr21:38,805,183...38,824,955
JBrowse link
G POU5F1 POU class 5 homeobox 1 ISO (MGI:1355046|PMID:10742100) MGI PMID:10742100 MGI:1355046 NCBI chr 6:31,164,337...31,170,682
Ensembl chr 6:31,164,337...31,180,731
JBrowse link
endoderm formation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CTNNB1 catenin beta 1 ISO (MGI:5498579|PMID:23824574)
(MGI:3625553|PMID:12194849)
MGI PMID:12194849, PMID:23824574 MGI:3625553, MGI:5498579 NCBI chr 3:41,199,422...41,240,445
Ensembl chr 3:41,194,741...41,260,096
JBrowse link
G DKK1 dickkopf WNT signaling pathway inhibitor 1 IEA Ensembl GO_REF:0000107 NCBI chr10:52,314,281...52,317,657
Ensembl chr10:52,314,281...52,318,042
JBrowse link
G DUSP1 dual specificity phosphatase 1 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 5:172,768,096...172,771,195
Ensembl chr 5:172,768,096...172,771,195
JBrowse link
G DUSP2 dual specificity phosphatase 2 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 2:96,143,166...96,145,468
Ensembl chr 2:96,143,169...96,145,440
JBrowse link
G DUSP4 dual specificity phosphatase 4 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 8:29,333,064...29,350,684
Ensembl chr 8:29,333,064...29,350,684
JBrowse link
G DUSP5 dual specificity phosphatase 5 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr10:110,497,907...110,511,533
Ensembl chr10:110,497,907...110,511,533
JBrowse link
G EOMES eomesodermin ISS UniProtKB GO_REF:0000024 NCBI chr 3:27,715,953...27,722,713
Ensembl chr 3:27,715,949...27,722,711
JBrowse link
G GATA4 GATA binding protein 4 ISO (MGI:77407|PMID:8582296) MGI PMID:8582296 MGI:77407 NCBI chr 8:11,676,931...11,760,002
Ensembl chr 8:11,676,959...11,760,002
JBrowse link
G LHX1 LIM homeobox 1 ISS UniProtKB GO_REF:0000024 NCBI chr17:36,937,475...36,944,612
Ensembl chr17:36,936,785...36,944,612
JBrowse link
G MIXL1 Mix paired-like homeobox ISO (MGI:3695524|PMID:17151016) MGI PMID:17151016 MGI:3695524 NCBI chr 1:226,223,664...226,227,060
Ensembl chr 1:226,223,618...226,227,060
Ensembl chr 1:226,223,618...226,227,060
JBrowse link
G NOG noggin IEA Ensembl GO_REF:0000107 NCBI chr17:56,593,699...56,595,611
Ensembl chr17:56,593,699...56,595,611
Ensembl chr17:56,593,699...56,595,611
JBrowse link
G SMAD2 SMAD family member 2 IEA Ensembl GO_REF:0000107 NCBI chr18:47,808,957...47,931,188
Ensembl chr18:47,808,957...47,931,146
JBrowse link
G SOX17 SRY-box transcription factor 17 IDA (PMID:18682240) UniProtKB PMID:18682240 NCBI chr 8:54,457,935...54,460,892
Ensembl chr 8:54,457,935...54,460,892
JBrowse link
G SOX7 SRY-box transcription factor 7 IDA (PMID:18682240) UniProtKB PMID:18682240 NCBI chr 8:10,723,768...10,730,511
Ensembl chr 8:10,723,768...10,730,511
JBrowse link
G TBX20 T-box transcription factor 20 ISS BHF-UCL GO_REF:0000024 NCBI chr 7:35,199,936...35,254,100
Ensembl chr 7:35,202,430...35,254,100
JBrowse link
G TNRC6C trinucleotide repeat containing adaptor 6C ISO (MGI:5315650|PMID:22187428) MGI PMID:22187428 MGI:5315650 NCBI chr17:77,958,853...78,108,835
Ensembl chr17:77,959,240...78,108,835
JBrowse link
endodermal cell differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COL11A1 collagen type XI alpha 1 chain IEP (PMID:23154389) UniProtKB PMID:23154389 NCBI chr 1:102,876,473...103,108,580
Ensembl chr 1:102,876,467...103,108,872
JBrowse link
G COL12A1 collagen type XII alpha 1 chain IEP
IBA
(PMID:23154389)
(PMID:21873635)
UniProtKB
GO_Central
PMID:21873635, PMID:23154389 NCBI chr 6:75,084,326...75,206,262
Ensembl chr 6:75,084,326...75,206,053
JBrowse link
G COL4A2 collagen type IV alpha 2 chain IEP (PMID:23154389) UniProtKB PMID:23154389 NCBI chr13:110,307,284...110,513,209
Ensembl chr13:110,305,812...110,513,209
JBrowse link
G COL6A1 collagen type VI alpha 1 chain IEP (PMID:23154389) UniProtKB PMID:23154389 NCBI chr21:45,981,770...46,005,048
Ensembl chr21:45,981,769...46,005,050
Ensembl chr21:45,981,769...46,005,050
JBrowse link
G COL7A1 collagen type VII alpha 1 chain IEP (PMID:23154389) UniProtKB PMID:23154389 NCBI chr 3:48,564,073...48,595,329
Ensembl chr 3:48,564,073...48,595,267
JBrowse link
G COL8A1 collagen type VIII alpha 1 chain IEP (PMID:23154389) UniProtKB PMID:23154389 NCBI chr 3:99,638,594...99,799,217
Ensembl chr 3:99,638,475...99,799,226
JBrowse link
G FN1 fibronectin 1 IDA (PMID:23154389) UniProtKB PMID:23154389 NCBI chr 2:215,360,862...215,436,167
Ensembl chr 2:215,360,440...215,436,073
JBrowse link
G GATA6 GATA binding protein 6 ISO (MGI:1315079|PMID:9832509) MGI PMID:9832509 MGI:1315079 NCBI chr18:22,169,589...22,202,528
Ensembl chr18:22,169,589...22,202,528
Ensembl chr18:22,169,589...22,202,528
JBrowse link
G HMGA2 high mobility group AT-hook 2 IMP (PMID:17624332) UniProtKB PMID:17624332 NCBI chr12:65,824,460...65,966,291
Ensembl chr12:65,824,460...65,966,291
Ensembl chr12:65,824,460...65,966,291
JBrowse link
G HSBP1 heat shock factor binding protein 1 ISO (MGI:5553204|PMID:24380799) MGI PMID:24380799 MGI:5553204 NCBI chr16:83,807,978...83,819,737
Ensembl chr16:83,807,978...83,819,737
JBrowse link
G INHBA inhibin subunit beta A IDA (PMID:21828274) BHF-UCL PMID:21828274 NCBI chr 7:41,685,101...41,710,532
Ensembl chr 7:41,667,168...41,705,834
JBrowse link
G ITGA4 integrin subunit alpha 4 IEP (PMID:23154389) UniProtKB PMID:23154389 NCBI chr 2:181,457,205...181,538,940
Ensembl chr 2:181,457,202...181,538,940
JBrowse link
G ITGA5 integrin subunit alpha 5 IMP (PMID:23154389) UniProtKB PMID:23154389 NCBI chr12:54,395,261...54,419,266
Ensembl chr12:54,395,261...54,419,266
JBrowse link
G ITGA7 integrin subunit alpha 7 IEP (PMID:23154389) UniProtKB PMID:23154389 NCBI chr12:55,684,568...55,716,037
Ensembl chr12:55,684,568...55,716,043
JBrowse link
G ITGAV integrin subunit alpha V IMP (PMID:23154389) UniProtKB PMID:23154389 NCBI chr 2:186,590,056...186,680,901
Ensembl chr 2:186,590,056...186,680,901
JBrowse link
G ITGB2 integrin subunit beta 2 IEP (PMID:23154389) UniProtKB PMID:23154389 NCBI chr21:44,885,949...44,928,815
Ensembl chr21:44,885,953...44,931,989
JBrowse link
G ITGB5 integrin subunit beta 5 IEP (PMID:23154389) UniProtKB PMID:23154389 NCBI chr 3:124,761,948...124,901,418
Ensembl chr 3:124,761,948...124,901,418
JBrowse link
G LAMA3 laminin subunit alpha 3 IEP (PMID:23154389) UniProtKB PMID:23154389 NCBI chr18:23,689,443...23,955,066
Ensembl chr18:23,689,443...23,956,222
JBrowse link
G LAMB1 laminin subunit beta 1 IEP (PMID:23154389) UniProtKB PMID:23154389 NCBI chr 7:107,923,799...108,003,176
Ensembl chr 7:107,923,799...108,003,187
JBrowse link
G LAMB3 laminin subunit beta 3 IEP (PMID:23154389) UniProtKB PMID:23154389 NCBI chr 1:209,614,870...209,652,467
Ensembl chr 1:209,614,870...209,652,425
JBrowse link
G MIXL1 Mix paired-like homeobox ISS BHF-UCL GO_REF:0000024 NCBI chr 1:226,223,664...226,227,060
Ensembl chr 1:226,223,618...226,227,060
Ensembl chr 1:226,223,618...226,227,060
JBrowse link
G MMP14 matrix metallopeptidase 14 IEP (PMID:23154389) UniProtKB PMID:23154389 NCBI chr14:22,836,585...22,847,758
Ensembl chr14:22,836,560...22,849,027
JBrowse link
G MMP15 matrix metallopeptidase 15 IEP (PMID:23154389) UniProtKB PMID:23154389 NCBI chr16:58,025,754...58,046,901
Ensembl chr16:58,025,754...58,046,901
JBrowse link
G MMP2 matrix metallopeptidase 2 IEP (PMID:23154389) UniProtKB PMID:23154389 NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691
JBrowse link
G MMP8 matrix metallopeptidase 8 IEP (PMID:23154389) UniProtKB PMID:23154389 NCBI chr11:102,711,796...102,724,967
Ensembl chr11:102,711,796...102,727,050
JBrowse link
G MMP9 matrix metallopeptidase 9 IEP (PMID:23154389) UniProtKB PMID:23154389 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561
JBrowse link
G NODAL nodal growth differentiation factor IMP (PMID:21741376) BHF-UCL PMID:21741376 NCBI chr10:70,431,936...70,447,951
Ensembl chr10:70,431,936...70,447,951
JBrowse link
G SETD2 SET domain containing 2, histone lysine methyltransferase ISS UniProtKB GO_REF:0000024 NCBI chr 3:47,016,431...47,164,113
Ensembl chr 3:47,016,429...47,164,113
Ensembl chr 3:47,016,429...47,164,113
JBrowse link
G VTN vitronectin IDA (PMID:23154389) UniProtKB PMID:23154389 NCBI chr17:28,367,284...28,370,307
Ensembl chr17:28,367,284...28,373,091
JBrowse link
endodermal cell fate commitment term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDC73 cell division cycle 73 ISS UniProtKB GO_REF:0000024 NCBI chr 1:193,122,031...193,254,815
Ensembl chr 1:193,121,958...193,254,815
Ensembl chr 1:193,121,958...193,254,815
JBrowse link
G CTNNB1 catenin beta 1 IEA Ensembl GO_REF:0000107 NCBI chr 3:41,199,422...41,240,445
Ensembl chr 3:41,194,741...41,260,096
JBrowse link
G CTR9 CTR9 homolog, Paf1/RNA polymerase II complex component ISS UniProtKB GO_REF:0000024 NCBI chr11:10,751,246...10,779,746
Ensembl chr11:10,751,246...10,801,625
JBrowse link
G LEO1 LEO1 homolog, Paf1/RNA polymerase II complex component ISS UniProtKB GO_REF:0000024 NCBI chr15:51,938,024...51,971,798
Ensembl chr15:51,938,025...51,971,778
JBrowse link
G PAF1 PAF1 homolog, Paf1/RNA polymerase II complex component ISS UniProtKB GO_REF:0000024 NCBI chr19:39,385,629...39,391,106
Ensembl chr19:39,385,629...39,391,154
JBrowse link
G POU5F1 POU class 5 homeobox 1 ISO (MGI:1355046|PMID:10742100) MGI PMID:10742100 MGI:1355046 NCBI chr 6:31,164,337...31,170,682
Ensembl chr 6:31,164,337...31,180,731
JBrowse link
G RTF1 RTF1 homolog, Paf1/RNA polymerase II complex component ISS UniProtKB GO_REF:0000024 NCBI chr15:41,417,104...41,483,563
Ensembl chr15:41,408,408...41,483,563
JBrowse link
endodermal cell fate determination term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GATA6 GATA binding protein 6 IEA Ensembl GO_REF:0000107 NCBI chr18:22,169,589...22,202,528
Ensembl chr18:22,169,589...22,202,528
Ensembl chr18:22,169,589...22,202,528
JBrowse link
G SOX17 SRY-box transcription factor 17 IEA Ensembl GO_REF:0000107 NCBI chr 8:54,457,935...54,460,892
Ensembl chr 8:54,457,935...54,460,892
JBrowse link
endodermal cell fate specification term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EOMES eomesodermin IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 3:27,715,953...27,722,713
Ensembl chr 3:27,715,949...27,722,711
JBrowse link
G HNF1B HNF1 homeobox B IEA Ensembl GO_REF:0000107 NCBI chr17:37,686,431...37,745,059
Ensembl chr17:37,686,431...37,745,105
JBrowse link
G NANOG Nanog homeobox IDA (PMID:20713518) MGI PMID:20713518 NCBI chr12:7,789,402...7,799,146
Ensembl chr12:7,787,794...7,799,146
JBrowse link
G POU5F1 POU class 5 homeobox 1 IDA (PMID:20713518) MGI PMID:20713518 NCBI chr 6:31,164,337...31,170,682
Ensembl chr 6:31,164,337...31,180,731
JBrowse link
G SOX2 SRY-box transcription factor 2 IDA (PMID:21245162) MGI PMID:21245162 NCBI chr 3:181,711,925...181,714,436
Ensembl chr 3:181,711,925...181,714,436
JBrowse link
hemangioblast cell differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TAL1 TAL bHLH transcription factor 1, erythroid differentiation factor IEA Ensembl GO_REF:0000107 NCBI chr 1:47,216,290...47,232,389
Ensembl chr 1:47,216,290...47,232,220
JBrowse link
intermediate mesodermal cell differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP4 bone morphogenetic protein 4 IDA (PMID:10021330) UniProtKB PMID:10021330 NCBI chr14:53,949,736...53,956,891
Ensembl chr14:53,949,736...53,958,761
JBrowse link
lateral mesoderm formation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TBX20 T-box transcription factor 20 ISS BHF-UCL GO_REF:0000024 NCBI chr 7:35,199,936...35,254,100
Ensembl chr 7:35,202,430...35,254,100
JBrowse link
lateral mesodermal cell differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FOXF1 forkhead box F1 IEA Ensembl GO_REF:0000107 NCBI chr16:86,510,527...86,515,422
Ensembl chr16:86,510,527...86,515,422
JBrowse link
mesoderm formation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACVR1 activin A receptor type 1 IEA Ensembl GO_REF:0000107 NCBI chr 2:157,736,446...157,876,330
Ensembl chr 2:157,736,444...157,876,330
Ensembl chr 2:157,736,444...157,876,330
JBrowse link
G ARMC5 armadillo repeat containing 5 IEA Ensembl GO_REF:0000107 NCBI chr16:31,458,273...31,467,167
Ensembl chr16:31,458,080...31,467,166
JBrowse link
G BMP4 bone morphogenetic protein 4 ISO (MGI:4415813|PMID:18462699), (MGI:70235|PMID:7799920) MGI PMID:7799920, PMID:18462699 MGI:4415813, MGI:70235 NCBI chr14:53,949,736...53,956,891
Ensembl chr14:53,949,736...53,958,761
JBrowse link
G BMP7 bone morphogenetic protein 7 IEA Ensembl GO_REF:0000107 NCBI chr20:57,168,753...57,266,641
Ensembl chr20:57,168,753...57,266,641
JBrowse link
G BMPR1A bone morphogenetic protein receptor type 1A IEA Ensembl GO_REF:0000107 NCBI chr10:86,755,786...86,927,969
Ensembl chr10:86,756,601...86,932,838
Ensembl chr10:86,756,601...86,932,838
JBrowse link
G BMPR2 bone morphogenetic protein receptor type 2 ISS BHF-UCL GO_REF:0000024 NCBI chr 2:202,376,310...202,567,751
Ensembl chr 2:202,376,327...202,567,751
JBrowse link
G CHRD chordin IEA Ensembl GO_REF:0000107 NCBI chr 3:184,380,073...184,390,739
Ensembl chr 3:184,380,073...184,390,736
JBrowse link
G CRB2 crumbs cell polarity complex component 2 ISS UniProtKB GO_REF:0000024 NCBI chr 9:123,354,065...123,380,326
Ensembl chr 9:123,356,170...123,380,324
JBrowse link
G DKK1 dickkopf WNT signaling pathway inhibitor 1 IEA Ensembl GO_REF:0000107 NCBI chr10:52,314,281...52,317,657
Ensembl chr10:52,314,281...52,318,042
JBrowse link
G ECSIT ECSIT signaling integrator ISO (MGI:2682456|PMID:14633973) MGI PMID:14633973 MGI:2682456 NCBI chr19:11,505,929...11,529,134
Ensembl chr19:11,505,929...11,529,172
JBrowse link
G EOMES eomesodermin ISS
IBA
(PMID:21873635) UniProtKB
GO_Central
PMID:21873635 GO_REF:0000024 NCBI chr 3:27,715,953...27,722,713
Ensembl chr 3:27,715,949...27,722,711
JBrowse link
G ETV2 ETS variant transcription factor 2 ISO (MGI:4415813|PMID:18462699) MGI PMID:18462699 MGI:4415813 NCBI chr19:35,641,175...35,644,871
Ensembl chr19:35,641,745...35,644,871
JBrowse link
G EXT2 exostosin glycosyltransferase 2 IEA Ensembl GO_REF:0000107 NCBI chr11:44,095,659...44,251,962
Ensembl chr11:44,095,673...44,251,981
Ensembl chr11:44,095,673...44,251,981
JBrowse link
G GPI glucose-6-phosphate isomerase IEA Ensembl GO_REF:0000107 NCBI chr19:34,353,330...34,402,413
Ensembl chr19:34,359,480...34,402,413
JBrowse link
G HAND1 heart and neural crest derivatives expressed 1 IEA Ensembl GO_REF:0000107 NCBI chr 5:154,474,972...154,478,227
Ensembl chr 5:154,474,972...154,478,227
JBrowse link
G INHBA inhibin subunit beta A ISO (MGI:70235|PMID:7799920) MGI PMID:7799920 MGI:70235 NCBI chr 7:41,685,101...41,710,532
Ensembl chr 7:41,667,168...41,705,834
JBrowse link
G MACF1 microtubule actin crosslinking factor 1 ISO (MGI:3640889|PMID:16815997) MGI PMID:16815997 MGI:3640889 NCBI chr 1:39,084,167...39,487,138
Ensembl chr 1:39,081,316...39,487,177
JBrowse link
G MESP1 mesoderm posterior bHLH transcription factor 1 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr15:89,734,772...89,751,309
Ensembl chr15:89,748,661...89,751,310
JBrowse link
G MESP2 mesoderm posterior bHLH transcription factor 2 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr15:89,776,332...89,778,754
Ensembl chr15:89,760,591...89,778,754
JBrowse link
G MSGN1 mesogenin 1 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 2:17,816,460...17,817,798
Ensembl chr 2:17,816,460...17,817,798
JBrowse link
G NF2 neurofibromin 2 IEA Ensembl GO_REF:0000107 NCBI chr22:29,603,556...29,698,600
Ensembl chr22:29,603,556...29,698,598
JBrowse link
G NODAL nodal growth differentiation factor ISO (MGI:2155575|PMID:11311163) MGI PMID:11311163 MGI:2155575 NCBI chr10:70,431,936...70,447,951
Ensembl chr10:70,431,936...70,447,951
JBrowse link
G NOG noggin IEA Ensembl GO_REF:0000107 NCBI chr17:56,593,699...56,595,611
Ensembl chr17:56,593,699...56,595,611
Ensembl chr17:56,593,699...56,595,611
JBrowse link
G NR4A3 nuclear receptor subfamily 4 group A member 3 IEA Ensembl GO_REF:0000107 NCBI chr 9:99,821,885...99,866,893
Ensembl chr 9:99,821,855...99,866,891
JBrowse link
G POFUT2 protein O-fucosyltransferase 2 IEA Ensembl GO_REF:0000107 NCBI chr21:45,263,928...45,287,914
Ensembl chr21:45,263,928...45,287,898
JBrowse link
G PRKACA protein kinase cAMP-activated catalytic subunit alpha IEA Ensembl GO_REF:0000107 NCBI chr19:14,091,688...14,117,762
Ensembl chr19:14,091,688...14,118,084
JBrowse link
G PRKAR1A protein kinase cAMP-dependent type I regulatory subunit alpha IEA Ensembl GO_REF:0000107 NCBI chr17:68,413,623...68,551,316
Ensembl chr17:68,511,780...68,551,319
JBrowse link
G SCX scleraxis bHLH transcription factor ISS UniProtKB GO_REF:0000024 NCBI chr 8:144,265,060...144,268,483
Ensembl chr 8:144,266,453...144,268,481
JBrowse link
G SMAD2 SMAD family member 2 ISS UniProtKB GO_REF:0000024 NCBI chr18:47,808,957...47,931,188
Ensembl chr18:47,808,957...47,931,146
JBrowse link
G SMAD3 SMAD family member 3 IEA Ensembl GO_REF:0000107 NCBI chr15:67,065,602...67,195,195
Ensembl chr15:67,063,763...67,195,169
JBrowse link
G SNAI1 snail family transcriptional repressor 1 ISS UniProtKB GO_REF:0000024 NCBI chr20:49,982,980...49,988,886
Ensembl chr20:49,982,980...49,988,886
JBrowse link
G SRF serum response factor IEA Ensembl GO_REF:0000107 NCBI chr 6:43,171,269...43,181,506
Ensembl chr 6:43,171,269...43,181,506
JBrowse link
G TBX19 T-box transcription factor 19 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:168,280,877...168,314,426
Ensembl chr 1:168,280,877...168,314,426
JBrowse link
G TBX6 T-box transcription factor 6 ISO (MGI:3577662|PMID:15755804)
(MGI:2447720|PMID:9490412)
MGI PMID:9490412, PMID:15755804 MGI:2447720, MGI:3577662 NCBI chr16:30,085,793...30,091,927
Ensembl chr16:30,085,793...30,091,924
Ensembl chr16:30,085,793...30,091,924
JBrowse link
G TBXT T-box transcription factor T IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 6:166,157,656...166,168,655
Ensembl chr 6:166,157,656...166,168,700
JBrowse link
G TLX2 T cell leukemia homeobox 2 IEA Ensembl GO_REF:0000107 NCBI chr 2:74,514,450...74,517,148
Ensembl chr 2:74,513,463...74,517,148
JBrowse link
G TWSG1 twisted gastrulation BMP signaling modulator 1 IEA Ensembl GO_REF:0000107 NCBI chr18:9,334,773...9,402,420
Ensembl chr18:9,334,767...9,402,420
JBrowse link
G TXNRD1 thioredoxin reductase 1 IEA Ensembl GO_REF:0000107 NCBI chr12:104,215,779...104,350,307
Ensembl chr12:104,215,779...104,350,307
JBrowse link
G WLS Wnt ligand secretion mediator IEA Ensembl GO_REF:0000107 NCBI chr 1:68,098,459...68,233,018
Ensembl chr 1:68,098,473...68,233,120
JBrowse link
G WNT3 Wnt family member 3 IEA Ensembl GO_REF:0000107 NCBI chr17:46,762,506...46,818,692
Ensembl chr17:46,762,506...46,833,154
JBrowse link
mesoderm migration involved in gastrulation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APELA apelin receptor early endogenous ligand ISS UniProtKB GO_REF:0000024 NCBI chr 4:164,877,023...164,899,063
Ensembl chr 4:164,877,178...164,898,965
JBrowse link
G EPB41L5 erythrocyte membrane protein band 4.1 like 5 IEA Ensembl GO_REF:0000107 NCBI chr 2:120,013,032...120,179,119
Ensembl chr 2:120,013,077...120,179,119
JBrowse link
G TBXT T-box transcription factor T IEA Ensembl GO_REF:0000107 NCBI chr 6:166,157,656...166,168,655
Ensembl chr 6:166,157,656...166,168,700
JBrowse link
mesodermal cell differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP4 bone morphogenetic protein 4 ISO (MGI:70235|PMID:7799920) MGI PMID:7799920 MGI:70235 NCBI chr14:53,949,736...53,956,891
Ensembl chr14:53,949,736...53,958,761
JBrowse link
G FGFR2 fibroblast growth factor receptor 2 IEA Ensembl GO_REF:0000107 NCBI chr10:121,478,330...121,598,458
Ensembl chr10:121,478,334...121,598,458
Ensembl chr10:121,478,334...121,598,458
JBrowse link
G HMGA2 high mobility group AT-hook 2 IMP (PMID:17624332) UniProtKB PMID:17624332 NCBI chr12:65,824,460...65,966,291
Ensembl chr12:65,824,460...65,966,291
Ensembl chr12:65,824,460...65,966,291
JBrowse link
G INHBA inhibin subunit beta A IEA Ensembl GO_REF:0000107 NCBI chr 7:41,685,101...41,710,532
Ensembl chr 7:41,667,168...41,705,834
JBrowse link
G ITGA2 integrin subunit alpha 2 IEP (PMID:23154389) UniProtKB PMID:23154389 NCBI chr 5:52,989,352...53,094,779
Ensembl chr 5:52,989,340...53,094,779
JBrowse link
G ITGA3 integrin subunit alpha 3 IEP (PMID:23154389) UniProtKB PMID:23154389 NCBI chr17:50,056,065...50,090,481
Ensembl chr17:50,055,968...50,090,481
JBrowse link
G ITGA8 integrin subunit alpha 8 IEP (PMID:23154389) UniProtKB PMID:23154389 NCBI chr10:15,513,954...15,720,329
Ensembl chr10:15,513,954...15,719,922
JBrowse link
G ITGB1 integrin subunit beta 1 IEP (PMID:23154389) UniProtKB PMID:23154389 NCBI chr10:32,900,318...32,958,230
Ensembl chr10:32,900,318...33,005,792
JBrowse link
G ITGB3 integrin subunit beta 3 IEP (PMID:23154389) UniProtKB PMID:23154389 NCBI chr17:47,253,827...47,313,743
Ensembl chr17:47,253,846...47,313,735
Ensembl chr17:47,253,846...47,313,735
Ensembl chr17:47,253,846...47,313,735
JBrowse link
G ITGB4 integrin subunit beta 4 IEP (PMID:23154389) UniProtKB PMID:23154389 NCBI chr17:75,721,339...75,757,819
Ensembl chr17:75,721,328...75,757,818
JBrowse link
G KDM6A lysine demethylase 6A IEA Ensembl GO_REF:0000107 NCBI chr  X:44,873,182...45,112,779
Ensembl chr  X:44,873,188...45,112,779
Ensembl chr  X:44,873,188...45,112,779
Ensembl chr  X:44,873,188...45,112,779
JBrowse link
G KDM6B lysine demethylase 6B ISS (PMID:23856522) BHF-UCL PMID:23856522 NCBI chr17:7,834,210...7,854,796
Ensembl chr17:7,839,904...7,854,796
JBrowse link
mesodermal cell fate commitment term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NANOG Nanog homeobox ISO (MGI:3654744|PMID:16801560) MGI PMID:16801560 MGI:3654744 NCBI chr12:7,789,402...7,799,146
Ensembl chr12:7,787,794...7,799,146
JBrowse link
G POU5F1 POU class 5 homeobox 1 ISO (MGI:1355046|PMID:10742100) MGI PMID:10742100 MGI:1355046 NCBI chr 6:31,164,337...31,170,682
Ensembl chr 6:31,164,337...31,180,731
JBrowse link
G SMAD1 SMAD family member 1 IEA Ensembl GO_REF:0000107 NCBI chr 4:145,481,306...145,559,176
Ensembl chr 4:145,481,194...145,559,176
JBrowse link
mesodermal cell fate determination term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP4 bone morphogenetic protein 4 IEA Ensembl GO_REF:0000107 NCBI chr14:53,949,736...53,956,891
Ensembl chr14:53,949,736...53,958,761
JBrowse link
G KLF4 Kruppel like factor 4 TAS (PMID:8940147) PINC PMID:8940147 NCBI chr 9:107,484,852...107,489,769
Ensembl chr 9:107,484,852...107,490,482
JBrowse link
G TRIM15 tripartite motif containing 15 TAS (PMID:10207104) PINC PMID:10207104 NCBI chr 6:30,163,546...30,172,693
Ensembl chr 6:30,163,206...30,172,693
JBrowse link
mesodermal cell fate specification term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EYA1 EYA transcriptional coactivator and phosphatase 1 IEA Ensembl GO_REF:0000107 NCBI chr 8:71,197,433...71,548,104
Ensembl chr 8:71,197,433...71,592,025
JBrowse link
G EYA2 EYA transcriptional coactivator and phosphatase 2 TAS (PMID:9020840) PINC PMID:9020840 NCBI chr20:46,894,843...47,188,844
Ensembl chr20:46,894,624...47,188,844
JBrowse link
G HOXA11 homeobox A11 ISS UniProtKB GO_REF:0000024 NCBI chr 7:27,181,157...27,185,232
Ensembl chr 7:27,181,157...27,185,232
Ensembl chr 7:27,181,157...27,185,232
JBrowse link
G PAX2 paired box 2 ISS UniProtKB GO_REF:0000024 NCBI chr10:100,735,396...100,829,944
Ensembl chr10:100,735,603...100,829,941
Ensembl chr10:100,735,603...100,829,941
JBrowse link
G SIX2 SIX homeobox 2 ISS UniProtKB GO_REF:0000024 NCBI chr 2:45,005,182...45,009,645
Ensembl chr 2:45,005,182...45,009,452
JBrowse link
negative regulation of ectodermal cell fate specification term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FZD7 frizzled class receptor 7 IMP (PMID:18681827) BHF-UCL PMID:18681827 NCBI chr 2:202,033,855...202,038,441
Ensembl chr 2:202,034,587...202,038,445
JBrowse link
negative regulation of endodermal cell differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COL5A1 collagen type V alpha 1 chain IDA (PMID:23154389) UniProtKB PMID:23154389 NCBI chr 9:134,641,789...134,844,843
Ensembl chr 9:134,641,803...134,844,843
Ensembl chr 9:134,641,803...134,844,843
JBrowse link
G COL5A2 collagen type V alpha 2 chain IDA (PMID:23154389) UniProtKB PMID:23154389 NCBI chr 2:189,031,898...189,225,301
Ensembl chr 2:189,031,898...189,225,312
JBrowse link
negative regulation of endodermal cell fate specification term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MESP1 mesoderm posterior bHLH transcription factor 1 ISS BHF-UCL GO_REF:0000024 NCBI chr15:89,734,772...89,751,309
Ensembl chr15:89,748,661...89,751,310
JBrowse link
negative regulation of mesodermal cell fate specification term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DKK1 dickkopf WNT signaling pathway inhibitor 1 IDA (PMID:20559569) BHF-UCL PMID:20559569 NCBI chr10:52,314,281...52,317,657
Ensembl chr10:52,314,281...52,318,042
JBrowse link
G MESP1 mesoderm posterior bHLH transcription factor 1 ISS BHF-UCL GO_REF:0000024 NCBI chr15:89,734,772...89,751,309
Ensembl chr15:89,748,661...89,751,310
JBrowse link
G SFRP2 secreted frizzled related protein 2 IEA Ensembl GO_REF:0000107 NCBI chr 4:153,780,591...153,789,083
Ensembl chr 4:153,780,591...153,789,083
JBrowse link
paraxial mesoderm formation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EXOC4 exocyst complex component 4 IEA Ensembl GO_REF:0000107 NCBI chr 7:133,253,075...134,067,137
Ensembl chr 7:133,253,073...134,066,589
JBrowse link
G FOXC1 forkhead box C1 IEA Ensembl GO_REF:0000107 NCBI chr 6:1,609,915...1,613,897
Ensembl chr 6:1,609,915...1,613,897
JBrowse link
G FOXC2 forkhead box C2 ISO (MGI:2150572|PMID:11562355) MGI PMID:11562355 MGI:2150572 NCBI chr16:86,566,829...86,569,728
Ensembl chr16:86,566,829...86,569,728
JBrowse link
G HNF1A HNF1 homeobox A IEA Ensembl GO_REF:0000107 NCBI chr12:120,977,683...121,002,512
Ensembl chr12:120,978,543...121,002,512
JBrowse link
G HTT huntingtin ISO (MGI:3609520|PMID:16109169) MGI PMID:16109169 MGI:3609520 NCBI chr 4:3,074,681...3,243,960
Ensembl chr 4:3,041,422...3,243,960
JBrowse link
G LEF1 lymphoid enhancer binding factor 1 IEA Ensembl GO_REF:0000107 NCBI chr 4:108,047,548...108,168,932
Ensembl chr 4:108,047,545...108,168,956
JBrowse link
G WNT11 Wnt family member 11 IEA Ensembl GO_REF:0000107 NCBI chr11:76,186,325...76,210,842
Ensembl chr11:76,186,325...76,210,736
JBrowse link
G WNT5A Wnt family member 5A IEA Ensembl GO_REF:0000107 NCBI chr 3:55,465,715...55,505,261
Ensembl chr 3:55,465,715...55,490,539
JBrowse link
paraxial mesodermal cell fate commitment term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FOXC2 forkhead box C2 IEA Ensembl GO_REF:0000107 NCBI chr16:86,566,829...86,569,728
Ensembl chr16:86,566,829...86,569,728
JBrowse link
G WNT3A Wnt family member 3A IEA Ensembl GO_REF:0000107 NCBI chr 1:228,006,998...228,067,113
Ensembl chr 1:228,006,998...228,061,271
JBrowse link
positive regulation of endodermal cell differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MACROH2A1 macroH2A.1 histone IMP (PMID:23595991) UniProt PMID:23595991 NCBI chr 5:135,334,381...135,401,998
Ensembl chr 5:135,333,900...135,399,914
JBrowse link
positive regulation of mesodermal cell differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GJA1 gap junction protein alpha 1 IMP (PMID:30599359) ARUK-UCL PMID:30599359 NCBI chr 6:121,435,646...121,449,727
Ensembl chr 6:121,435,595...121,449,727
JBrowse link
positive regulation of mesodermal cell fate specification term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G WNT3A Wnt family member 3A IDA (PMID:20559569) BHF-UCL PMID:20559569 NCBI chr 1:228,006,998...228,067,113
Ensembl chr 1:228,006,998...228,061,271
JBrowse link
regulation of endodermal cell fate specification term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DKK1 dickkopf WNT signaling pathway inhibitor 1 IDA (PMID:20559569) BHF-UCL PMID:20559569 NCBI chr10:52,314,281...52,317,657
Ensembl chr10:52,314,281...52,318,042
JBrowse link
regulation of lateral mesodermal cell fate specification term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMPR1A bone morphogenetic protein receptor type 1A IEA Ensembl GO_REF:0000107 NCBI chr10:86,755,786...86,927,969
Ensembl chr10:86,756,601...86,932,838
Ensembl chr10:86,756,601...86,932,838
JBrowse link
G FGFR1 fibroblast growth factor receptor 1 IEA Ensembl GO_REF:0000107 NCBI chr 8:38,411,143...38,468,635
Ensembl chr 8:38,400,215...38,468,834
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18673
    developmental process 7467
      anatomical structure formation involved in morphogenesis 1278
        formation of primary germ layer 132
          cell fate commitment involved in formation of primary germ layer + 34
          ectoderm formation + 6
          endoderm formation + 57
          mesoderm formation + 79
Path 2
Term Annotations click to browse term
  biological_process 18673
    developmental process 7467
      anatomical structure development 6874
        multicellular organism development 6347
          embryo development 1326
            embryonic morphogenesis 700
              gastrulation 208
                formation of primary germ layer 132
                  cell fate commitment involved in formation of primary germ layer + 34
                  ectoderm formation + 6
                  endoderm formation + 57
                  mesoderm formation + 79
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.