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ONTOLOGY REPORT - ANNOTATIONS


Term:endodermal cell fate specification
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Accession:GO:0001714 term browser browse the term
Definition:The cell fate determination process that results in a cell becoming capable of differentiating autonomously into an endoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.
Synonyms:exact_synonym: endoderm cell fate specification


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endodermal cell fate specification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Eomes eomesodermin JBrowse link 8 127,144,367 127,152,618 RGD:1624291
RGD:1600115
G Hnf1b HNF1 homeobox B JBrowse link 10 71,159,863 71,218,902 RGD:1624291
RGD:1600115
G Nanog Nanog homeobox JBrowse link 4 155,531,906 155,539,268 RGD:1624291
G Pou5f1 POU class 5 homeobox 1 JBrowse link 20 3,747,231 3,751,994 RGD:1624291
G Sox2 SRY-box transcription factor 2 JBrowse link 2 121,165,137 121,167,545 RGD:1624291
RGD:1600115
negative regulation of endodermal cell fate specification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mesp1 mesoderm posterior bHLH transcription factor 1 JBrowse link 1 141,532,390 141,533,908 RGD:1624291
RGD:1600115
regulation of endodermal cell fate specification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 JBrowse link 1 248,952,896 248,956,579 RGD:1624291
regulation of transcription from RNA polymerase II promoter involved in definitive endodermal cell fate specification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Sox17 SRY-box transcription factor 17 JBrowse link 5 14,890,318 14,895,907 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19317
    developmental process 6647
      cellular developmental process 4428
        cell fate specification 104
          endodermal cell fate specification 8
            negative regulation of endodermal cell fate specification 1
            regulation of endodermal cell fate specification + 2
            regulation of transcription from RNA polymerase II promoter involved in definitive endodermal cell fate specification 1
            transforming growth factor beta receptor signaling pathway involved in endodermal cell fate specification 0
Path 2
Term Annotations click to browse term
  biological_process 19317
    developmental process 6647
      anatomical structure development 6113
        multicellular organism development 5583
          embryo development 1301
            embryonic morphogenesis 683
              gastrulation 204
                formation of primary germ layer 126
                  endoderm formation 55
                    endodermal cell differentiation 45
                      endodermal cell fate commitment 15
                        endodermal cell fate specification 8
                          negative regulation of endodermal cell fate specification 1
                          regulation of endodermal cell fate specification + 2
                          regulation of transcription from RNA polymerase II promoter involved in definitive endodermal cell fate specification 1
                          transforming growth factor beta receptor signaling pathway involved in endodermal cell fate specification 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.