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ONTOLOGY REPORT - ANNOTATIONS


Term:neural tube closure
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Accession:GO:0001843 term browser browse the term
Definition:The last step in the formation of the neural tube, where the paired neural folds are brought together and fuse at the dorsal midline.


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neural tube closure term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase ISO MGI:87860 (MGI:1327082|PMID:9883720) RGD PMID:9883720 MGI:1327082 NCBI chr 3:10,041,820...10,145,076
Ensembl chr 3:10,041,826...10,144,388
JBrowse link
G Abl2 ABL proto-oncogene 2, non-receptor tyrosine kinase ISO MGI:87859 (MGI:1327082|PMID:9883720) RGD PMID:9883720 MGI:1327082 NCBI chr13:74,154,533...74,333,244
Ensembl chr13:74,154,835...74,333,244
JBrowse link
G Adm adrenomedullin ISO MGI:2176598 (MGI:3689296|PMID:16981008) RGD PMID:16981008 MGI:3689296 NCBI chr 1:175,443,189...175,447,260
Ensembl chr 1:175,445,088...175,447,259
JBrowse link
G Alx1 ALX homeobox 1 ISO MGI:1857553 (MGI:81193|PMID:8673125) RGD PMID:8673125 MGI:81193 NCBI chr 7:44,751,865...44,771,458
Ensembl chr 7:44,751,873...44,771,458
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 ISO MGI:1888997 (MGI:2149166|PMID:11504943), (MGI:893797|PMID:9216040) RGD PMID:9216040, PMID:11504943 MGI:2149166, MGI:893797 NCBI chr 7:31,699,309...31,784,192
Ensembl chr 7:31,699,885...31,784,192
JBrowse link
G Arhgap35 Rho GTPase activating protein 35 IEA
ISO
GO_REF:0000107
MGI:2448591 (MGI:1926242|PMID:11044403)
Ensembl
RGD
PMID:11044403 GO_REF:0000107, MGI:1926242 NCBI chr 1:78,456,409...78,573,374
Ensembl chr 1:78,456,409...78,573,374
JBrowse link
G Arid1a AT-rich interaction domain 1A ISO MGI:5469314 (MGI:5466629|PMID:23129809) RGD PMID:23129809 MGI:5466629 NCBI chr 5:151,904,687...151,977,973
Ensembl chr 5:151,904,684...151,977,636
JBrowse link
G Bbs4 Bardet-Biedl syndrome 4 ISO MGI:3055492 (MGI:3607949|PMID:16170314) RGD PMID:16170314 MGI:3607949 NCBI chr 8:64,115,005...64,154,432
Ensembl chr 8:64,121,392...64,154,396
JBrowse link
G Bcl10 BCL10, immune signaling adaptor ISS
ISO
PMID:11163238
(MGI:1930354|PMID:11163238)
RGD PMID:11163238, PMID:11163238 MGI:1930354, RGD:734638 NCBI chr 2:251,805,392...251,814,957
Ensembl chr 2:251,805,392...251,814,957
JBrowse link
G Bmp4 bone morphogenetic protein 4 IEA
ISO
GO_REF:0000107
(MGI:4429763|PMID:19850029)
Ensembl
RGD
PMID:19850029 GO_REF:0000107, MGI:4429763 NCBI chr15:20,776,060...20,791,013
Ensembl chr15:20,776,054...20,822,740
JBrowse link
G Cc2d2a coiled-coil and C2 domain containing 2A ISO MGI:5708063 (MGI:5696765|PMID:24947469) RGD PMID:24947469 MGI:5696765 NCBI chr14:71,895,128...71,979,452
Ensembl chr14:71,895,246...71,973,419
JBrowse link
G Cdk20 cyclin-dependent kinase 20 ISO MGI:6113512 (MGI:5912686|PMID:28817564) RGD PMID:28817564 MGI:5912686 NCBI chr17:1,935,900...1,942,867
Ensembl chr17:1,936,163...1,942,865
JBrowse link
G Cecr2 CECR2, histone acetyl-lysine reader ISO MGI:2135272|MGI:3574034|MGI:4829945 (MGI:3530173|PMID:15640247), (MGI:4822542|PMID:20589882), (MGI:4880797|PMID:21246654) RGD PMID:15640247, PMID:20589882, PMID:21246654 MGI:3530173, MGI:4822542, MGI:4880797 NCBI chr 4:153,217,521...153,327,153
Ensembl chr 4:153,217,782...153,322,564
JBrowse link
G Celsr1 cadherin, EGF LAG seven-pass G-type receptor 1 ISO MGI:107926|MGI:2135272 (MGI:2667273|PMID:12842012), (MGI:3703464|PMID:17229766) RGD PMID:12842012, PMID:17229766 MGI:2667273, MGI:3703464 NCBI chr 7:126,774,010...126,914,085
Ensembl chr 7:126,775,516...126,913,585
JBrowse link
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 ISO MGI:2385355 (MGI:2384266|PMID:12149478) RGD PMID:12149478 MGI:2384266 NCBI chr 1:12,823,363...12,825,806
Ensembl chr 1:12,823,363...12,825,786
JBrowse link
G Cluap1 clusterin associated protein 1 ISO MGI:5523142 (MGI:5509110|PMID:23742838) RGD PMID:23742838 MGI:5509110 NCBI chr10:11,847,058...11,878,792
Ensembl chr10:11,847,102...11,878,792
JBrowse link
G Cobl cordon-bleu WH2 repeat protein IEA
ISO
GO_REF:0000107
MGI:2135272 (MGI:2676511|PMID:14512015)
Ensembl
RGD
PMID:14512015 GO_REF:0000107, MGI:2676511 NCBI chr14:92,341,949...92,497,169
Ensembl chr14:92,342,957...92,577,936
JBrowse link
G Deaf1 DEAF1 transcription factor ISS
ISO
GO_REF:0000024
(MGI:3029622|PMID:14966286)
UniProt
RGD
PMID:14966286 GO_REF:0000024, MGI:3029622 NCBI chr 1:214,283,787...214,317,466
Ensembl chr 1:214,283,790...214,317,466
JBrowse link
G Dlc1 DLC1 Rho GTPase activating protein ISO MGI:3529997 (MGI:3529660|PMID:15710412) RGD PMID:15710412 MGI:3529660 NCBI chr16:58,776,489...59,247,752
Ensembl chr16:59,077,574...59,247,754
JBrowse link
G Dvl2 dishevelled segment polarity protein 2 ISO MGI:2429760 (MGI:2389015|PMID:12421720) RGD PMID:12421720 MGI:2389015 NCBI chr10:56,609,810...56,619,269
Ensembl chr10:56,610,051...56,619,269
JBrowse link
G Enah ENAH, actin regulator ISO MGI:109268|MGI:97549 (MGI:1331576|PMID:10069337), (MGI:3054149|PMID:15371503) RGD PMID:10069337, PMID:15371503 MGI:1331576, MGI:3054149 NCBI chr13:100,297,421...100,415,335
Ensembl chr13:100,300,054...100,414,226
JBrowse link
G Fuz fuzzy planar cell polarity protein ISO
ISS
(PMID:21840926)
MGI:4346364 (MGI:4367921|PMID:19877275), (MGI:4438317|PMID:19767740), (MGI:5296277|PMID:21840926)
GO_REF:0000024
RGD
UniProt
PMID:19767740, PMID:19877275, PMID:21840926 GO_REF:0000024, MGI:4367921, MGI:4438317, MGI:5296277 NCBI chr 1:100,891,832...100,896,811
Ensembl chr 1:100,891,866...100,896,807
JBrowse link
G Fzd3 frizzled class receptor 3 ISO MGI:108474 (MGI:3616416|PMID:16495441) RGD PMID:16495441 MGI:3616416 NCBI chr15:48,601,259...48,670,257
Ensembl chr15:48,601,266...48,670,257
JBrowse link
G Fzd6 frizzled class receptor 6 ISO MGI:108476 (MGI:3616416|PMID:16495441) RGD PMID:16495441 MGI:3616416 NCBI chr 7:77,898,329...77,931,034
Ensembl chr 7:77,899,322...77,931,029
JBrowse link
G Glmn glomulin, FKBP associated protein ISO MGI:3817643 (MGI:5320488|PMID:22405651) RGD PMID:22405651 MGI:5320488 NCBI chr14:3,204,390...3,247,703
Ensembl chr14:3,204,390...3,247,695
JBrowse link
G Grhl2 grainyhead-like transcription factor 2 ISO MGI:4331210 (MGI:4835348|PMID:20654612), (MGI:4867118|PMID:20978075), (MGI:4947318|PMID:21262862) RGD PMID:20654612, PMID:20978075, PMID:21262862 MGI:4835348, MGI:4867118, MGI:4947318 NCBI chr 7:76,058,623...76,197,360
Ensembl chr 7:76,059,386...76,197,856
JBrowse link
G Grhl3 grainyhead-like transcription factor 3 ISO (MGI:3689640|PMID:16949565), (MGI:4835348|PMID:20654612) RGD PMID:16949565, PMID:20654612 MGI:3689640, MGI:4835348 NCBI chr 5:153,893,039...153,925,045
Ensembl chr 5:153,893,039...153,924,896
JBrowse link
G Hectd1 HECT domain E3 ubiquitin protein ligase 1 ISO MGI:2137552 (MGI:1267118|PMID:9636176), (MGI:3577662|PMID:15755804), (MGI:3714713|PMID:17442300) RGD PMID:9636176, PMID:15755804, PMID:17442300 MGI:1267118, MGI:3577662, MGI:3714713 NCBI chr 6:72,509,658...72,596,285
Ensembl chr 6:72,510,255...72,596,446
JBrowse link
G Ift122 intraflagellar transport 122 ISO (MGI:3827087|PMID:19000668) RGD PMID:19000668 MGI:3827087 NCBI chr 4:147,756,574...147,826,983
Ensembl chr 4:147,756,553...147,826,997
JBrowse link
G Ift172 intraflagellar transport 172 ISO MGI:3829198 (MGI:3828200|PMID:18930042) RGD PMID:18930042 MGI:3828200 NCBI chr 6:26,390,686...26,485,459 JBrowse link
G Ift57 intraflagellar transport 57 ISO MGI:3707373 (MGI:3703110|PMID:17027958) RGD PMID:17027958 MGI:3703110 NCBI chr11:53,664,638...53,731,779
Ensembl chr11:53,664,638...53,731,779
JBrowse link
G Kat2a lysine acetyltransferase 2A ISO MGI:3711317 (MGI:3709911|PMID:17325035) RGD PMID:17325035 MGI:3709911 NCBI chr10:88,611,586...88,619,558
Ensembl chr10:88,611,586...88,619,537
JBrowse link
G Kdm2a lysine demethylase 2A ISO (MGI:5615026|PMID:25463925) RGD PMID:25463925 MGI:5615026 NCBI chr 1:219,566,130...219,642,294
Ensembl chr 1:219,566,156...219,640,294
JBrowse link
G Kdm6a lysine demethylase 6A ISO MGI:5448825 (MGI:5448135|PMID:22949634) RGD PMID:22949634 MGI:5448135 NCBI chr  X:4,805,493...4,945,788
Ensembl chr  X:4,806,277...4,945,944
JBrowse link
G Kif20b kinesin family member 20B ISO MGI:3578531 (MGI:3577662|PMID:15755804) RGD PMID:15755804 MGI:3577662 NCBI chr 1:253,220,038...253,275,523
Ensembl chr 1:253,221,812...253,275,490
JBrowse link
G Lhx2 LIM homeobox 2 ISO MGI:1890208 (MGI:2154554|PMID:11719201) RGD PMID:11719201 MGI:2154554 NCBI chr 3:22,628,674...22,658,447
Ensembl chr 3:22,640,545...22,658,446
JBrowse link
G Lias lipoic acid synthetase ISO MGI:3578174 (MGI:3577662|PMID:15755804) RGD PMID:15755804 MGI:3577662 NCBI chr14:44,507,217...44,524,287
Ensembl chr14:44,507,218...44,524,252
JBrowse link
G Lmo4 LIM domain only 4 ISO MGI:3035827|MGI:3574586 (MGI:3029621|PMID:14966285), (MGI:3573996|PMID:15691703), (MGI:3689640|PMID:16949565) RGD PMID:14966285, PMID:15691703, PMID:16949565 MGI:3029621, MGI:3573996, MGI:3689640 NCBI chr 2:250,218,635...250,235,435
Ensembl chr 2:250,218,641...250,241,673
JBrowse link
G LOC100909544 bromodomain-containing protein 2-like ISO MGI:3840071 (MGI:6120662|PMID:19362612) RGD PMID:19362612 MGI:6120662 NCBI chr20:3,910,555...3,918,348
Ensembl chr20:3,910,555...3,917,426
JBrowse link
G Lrp2 LDL receptor related protein 2 IEA
ISO
ISS
GO_REF:0000107
(MGI:5603707|PMID:24639464)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:24639464 GO_REF:0000024, GO_REF:0000107, MGI:5603707 NCBI chr 3:55,665,153...55,822,484
Ensembl chr 3:55,665,145...55,822,551
JBrowse link
G Lrp6 LDL receptor related protein 6 IBA
ISO
PMID:21873635
MGI:1861309|MGI:2673982|MGI:4415718|MGI:98958 (MGI:1347661|PMID:10545599), (MGI:3055483|PMID:15469977), (MGI:4413372|PMID:19795512), (MGI:4413396|PMID:19653321)
RGD PMID:10545599, PMID:15469977, PMID:19653321, PMID:19795512, PMID:21873635 MGI:1347661, MGI:3055483, MGI:4413372, MGI:4413396, MGI:61254, RGD:13792537 NCBI chr 4:168,194,054...168,323,962
Ensembl chr 4:168,194,927...168,323,751
JBrowse link
G Med12 mediator complex subunit 12 ISO MGI:4839484 (MGI:4839483|PMID:20630950) RGD PMID:20630950 MGI:4839483 NCBI chr  X:71,174,653...71,197,812
Ensembl chr  X:71,174,699...71,197,812
JBrowse link
G Mks1 MKS transition zone complex subunit 1 IEA
ISO
GO_REF:0000107
MGI:4410614|MGI:4433029 (MGI:4367169|PMID:19776033), (MGI:5487695|PMID:23454480)
Ensembl
RGD
PMID:19776033, PMID:23454480 GO_REF:0000107, MGI:4367169, MGI:5487695 NCBI chr10:75,149,814...75,160,481
Ensembl chr10:75,149,814...75,160,480
JBrowse link
G Mthfd1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 ISO (MGI:5503248|PMID:23704330) RGD PMID:23704330 MGI:5503248 NCBI chr 6:99,282,850...99,350,367
Ensembl chr 6:99,282,850...99,350,340
JBrowse link
G Mthfd1l methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like ISO (MGI:5468075|PMID:23267094) RGD PMID:23267094 MGI:5468075 NCBI chr 1:40,529,092...40,719,232
Ensembl chr 1:40,529,045...40,719,391
JBrowse link
G Mthfr methylenetetrahydrofolate reductase ISO (PMID:25855017), (PMID:29222906) RGD PMID:25855017, PMID:29222906 NCBI chr 5:164,844,642...164,864,360
Ensembl chr 5:164,845,925...164,860,910
JBrowse link
G Nckap1 NCK-associated protein 1 ISO MGI:3578145 (MGI:3701029|PMID:16831833) RGD PMID:16831833 MGI:3701029 NCBI chr 3:67,725,180...67,804,680
Ensembl chr 3:67,725,947...67,787,990
JBrowse link
G Nog noggin IEA
ISO
GO_REF:0000107
MGI:1856173|MGI:1862000 (MGI:3640733|PMID:16712836)
Ensembl
RGD
PMID:16712836 GO_REF:0000107, MGI:3640733 NCBI chr10:76,811,759...76,813,386
Ensembl chr10:76,811,759...76,813,386
JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase ISO MGI:3578528 (MGI:3577662|PMID:15755804) RGD PMID:15755804 MGI:3577662 NCBI chr11:74,717,600...74,793,902
Ensembl chr11:74,720,254...74,793,803
JBrowse link
G Pax2 paired box 2 ISS
ISO
GO_REF:0000024
(MGI:84247|PMID:8951055)
UniProt
RGD
PMID:8951055 GO_REF:0000024, MGI:84247 NCBI chr 1:264,493,579...264,585,073
Ensembl chr 1:264,504,591...264,583,329
JBrowse link
G Pax3 paired box 3 ISO MGI:3043030 (MGI:3056222|PMID:15384171) RGD PMID:15384171 MGI:3056222 NCBI chr 9:84,004,004...84,101,226
Ensembl chr 9:84,005,183...84,101,172
JBrowse link
G Pfn1 profilin 1 ISO MGI:108360 (MGI:1331576|PMID:10069337) RGD PMID:10069337 MGI:1331576 NCBI chr10:57,273,003...57,275,708
Ensembl chr10:57,273,005...57,275,708
JBrowse link
G Phactr4 phosphatase and actin regulator 4 ISO (MGI:3719969|PMID:17609112) RGD PMID:17609112 MGI:3719969 NCBI chr 5:150,533,895...150,609,423
Ensembl chr 5:150,546,430...150,609,352
JBrowse link
G Plxnb2 plexin B2 ISO (MGI:3712712|PMID:17554007) RGD PMID:17554007 MGI:3712712 NCBI chr 7:130,135,484...130,161,568
Ensembl chr 7:130,135,464...130,151,880
JBrowse link
G Prickle1 prickle planar cell polarity protein 1 IEA
ISO
GO_REF:0000107
(PMID:21901791)
Ensembl
RGD
PMID:21901791 GO_REF:0000107 NCBI chr 7:134,702,964...134,799,437
Ensembl chr 7:134,702,964...134,722,215
JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha IEA
ISO
GO_REF:0000107
MGI:97760 (MGI:5308523|PMID:22007132)
Ensembl
RGD
PMID:22007132 GO_REF:0000107, MGI:5308523 NCBI chr19:25,095,089...25,118,869
Ensembl chr19:25,095,089...25,118,860
JBrowse link
G Prkacb protein kinase cAMP-activated catalytic subunit beta ISO MGI:97592 (MGI:5308523|PMID:22007132) RGD PMID:22007132 MGI:5308523 NCBI chr 2:252,602,197...252,691,886
Ensembl chr 2:252,605,307...252,691,886
JBrowse link
G Ptch1 patched 1 ISO MGI:1857447 (MGI:1095757|PMID:9262482) RGD PMID:9262482 MGI:1095757 NCBI chr17:1,032,242...1,085,885
Ensembl chr17:1,029,048...1,093,873
JBrowse link
G Ptk7 protein tyrosine kinase 7 ISO MGI:2135272|MGI:3046905|MGI:3640803 (MGI:3046397|PMID:15229603), (MGI:4830023|PMID:20704721) RGD PMID:15229603, PMID:20704721 MGI:3046397, MGI:4830023 NCBI chr 9:16,662,588...16,729,888
Ensembl chr 9:16,702,460...16,729,030
JBrowse link
G Rab23 RAB23, member RAS oncogene family ISO MGI:2137533 (MGI:1267118|PMID:9636176), (MGI:69552|PMID:7720556) RGD PMID:7720556, PMID:9636176 MGI:1267118, MGI:69552 NCBI chr 9:38,469,784...38,496,185
Ensembl chr 9:38,470,298...38,495,176
JBrowse link
G Rala RAS like proto-oncogene A ISO (MGI:5504565|PMID:23063435) RGD PMID:23063435 MGI:5504565 NCBI chr17:49,676,073...49,729,133
Ensembl chr17:49,714,294...49,727,664
JBrowse link
G Rara retinoic acid receptor, alpha ISO MGI:97858 (MGI:69060|PMID:7607067) RGD PMID:7607067 MGI:69060 NCBI chr10:86,838,819...86,884,224
Ensembl chr10:86,860,685...86,884,210
JBrowse link
G Rarg retinoic acid receptor, gamma ISO MGI:97856 (MGI:69060|PMID:7607067) RGD PMID:7607067 MGI:69060 NCBI chr 7:143,840,739...143,863,206
Ensembl chr 7:143,839,980...143,863,186
JBrowse link
G Rgma repulsive guidance molecule BMP co-receptor a ISO MGI:3029714 (MGI:3027667|PMID:14749425) RGD PMID:14749425 MGI:3027667 NCBI chr 1:134,699,053...134,742,512
Ensembl chr 1:134,699,299...134,742,514
JBrowse link
G Rock2 Rho-associated coiled-coil containing protein kinase 2 ISO MGI:1100883|MGI:2135272 (MGI:3703464|PMID:17229766) RGD PMID:17229766 MGI:3703464 NCBI chr 6:42,180,864...42,289,910
Ensembl chr 6:42,180,894...42,289,908
JBrowse link
G Rps7 ribosomal protein S7 ISO MGI:3043039 (MGI:3056222|PMID:15384171) RGD PMID:15384171 MGI:3056222 NCBI chr 6:47,899,525...47,904,389
Ensembl chr 6:47,899,525...47,904,437
JBrowse link
G Sall1 spalt-like transcription factor 1 ISO MGI:2139360 (MGI:3698636|PMID:16790473) RGD PMID:16790473 MGI:3698636 NCBI chr19:23,387,737...23,405,025
Ensembl chr19:23,389,375...23,405,039
JBrowse link
G Sall4 spalt-like transcription factor 4 ISO MGI:1889585|MGI:3699175 (MGI:3698636|PMID:16790473) RGD PMID:16790473 MGI:3698636 NCBI chr 3:165,520,155...165,538,176
Ensembl chr 3:165,520,392...165,537,940
JBrowse link
G Scrib scribble planar cell polarity protein ISO (PMID:22095531)
MGI:1889322|MGI:2135272|MGI:5056373 (MGI:4819429|PMID:20643356), (MGI:5050793|PMID:21515572)
RGD PMID:20643356, PMID:21515572, PMID:22095531 MGI:4819429, MGI:5050793 NCBI chr 7:117,105,810...117,128,802
Ensembl chr 7:117,105,810...117,128,798
JBrowse link
G Sdc4 syndecan 4 ISO MGI:2135272 (MGI:5498591|PMID:23760952) RGD PMID:23760952 MGI:5498591 NCBI chr 3:160,872,503...160,891,190
Ensembl chr 3:160,872,503...160,891,190
JBrowse link
G Sec24b SEC24 homolog B, COPII coat complex component ISO MGI:2135272|MGI:4440621 (MGI:4438817|PMID:19966784), (MGI:4439427|PMID:20215345) RGD PMID:19966784, PMID:20215345 MGI:4438817, MGI:4439427 NCBI chr 2:230,286,886...230,356,887
Ensembl chr 2:230,287,296...230,356,919
JBrowse link
G Sema4c semaphorin 4C ISO (MGI:4881530|PMID:21122816) RGD PMID:21122816 MGI:4881530 NCBI chr 9:43,129,413...43,140,442
Ensembl chr 9:43,129,415...43,139,870
JBrowse link
G Setd2 SET domain containing 2, histone lysine methyltransferase ISO MGI:4437211 (MGI:4431136|PMID:20133625) RGD PMID:20133625 MGI:4431136 NCBI chr 8:118,802,478...118,888,224
Ensembl chr 8:118,803,075...118,888,224
JBrowse link
G Sfrp1 secreted frizzled-related protein 1 ISO MGI:108078 (MGI:4429763|PMID:19850029) RGD PMID:19850029 MGI:4429763 NCBI chr16:73,372,007...73,410,777
Ensembl chr16:73,372,007...73,410,777
JBrowse link
G Sfrp2 secreted frizzled-related protein 2 ISO MGI:892014 (MGI:4429763|PMID:19850029) RGD PMID:19850029 MGI:4429763 NCBI chr 2:182,723,732...182,731,277
Ensembl chr 2:182,723,854...182,731,764
JBrowse link
G Shroom3 shroom family member 3 ISO MGI:1889778 (MGI:3610718|PMID:16249236) RGD PMID:16249236 MGI:3610718 NCBI chr14:16,622,767...16,903,265
Ensembl chr14:16,622,760...16,903,242
JBrowse link
G Ski SKI proto-oncogene ISO MGI:2177555 (MGI:1095997|PMID:9284043) RGD PMID:9284043 MGI:1095997 NCBI chr 5:172,556,196...172,623,878
Ensembl chr 5:172,559,135...172,623,899
JBrowse link
G Spint1 serine peptidase inhibitor, Kunitz type 1 ISO MGI:1338031|MGI:1338881 (MGI:4360135|PMID:19592578) RGD PMID:19592578 MGI:4360135 NCBI chr 3:111,049,132...111,061,991
Ensembl chr 3:111,049,118...111,062,011
JBrowse link
G Spint2 serine peptidase inhibitor, Kunitz type, 2 ISO MGI:1338033|MGI:1338881|MGI:2156187 (MGI:4360135|PMID:19592578) RGD PMID:19592578 MGI:4360135 NCBI chr 1:87,199,373...87,221,826
Ensembl chr 1:87,199,313...87,221,892
JBrowse link
G St14 ST14 transmembrane serine protease matriptase ISO MGI:1338031|MGI:1338033 (MGI:4360135|PMID:19592578) RGD PMID:19592578 MGI:4360135 NCBI chr 8:32,240,113...32,280,813
Ensembl chr 8:32,240,133...32,280,869
JBrowse link
G Stil STIL, centriolar assembly protein ISO MGI:2152962 (MGI:1339521|PMID:10385121) RGD PMID:10385121 MGI:1339521 NCBI chr 5:133,819,302...133,851,362
Ensembl chr 5:133,819,726...133,851,416
JBrowse link
G Sufu SUFU negative regulator of hedgehog signaling ISO MGI:3512046 (MGI:3604917|PMID:16155214) RGD PMID:16155214 MGI:3604917 NCBI chr 1:266,143,766...266,241,742
Ensembl chr 1:266,143,818...266,239,016
JBrowse link
G Tbxt T-box transcription factor T ISO MGI:1856158 (MGI:3701028|PMID:16835439) RGD PMID:16835439 MGI:3701028 NCBI chr 1:52,887,067...52,900,691
Ensembl chr 1:52,887,067...52,894,832
JBrowse link
G Tead2 TEA domain transcription factor 2 ISO MGI:3763367 (MGI:3763398|PMID:17868131) RGD PMID:17868131 MGI:3763398 NCBI chr 1:101,213,782...101,230,483
Ensembl chr 1:101,213,788...101,230,477
JBrowse link
G Tfap2a transcription factor AP-2 alpha ISO MGI:2176682 (MGI:1313057|PMID:9811866), (MGI:80519|PMID:8622766) RGD PMID:8622766, PMID:9811866 MGI:1313057, MGI:80519 NCBI chr17:24,653,342...24,670,457
Ensembl chr17:24,654,902...24,670,457
JBrowse link
G Tgfb1 transforming growth factor, beta 1 ISO (MGI:74339|PMID:7600998) RGD PMID:7600998 MGI:74339 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Tgfb2 transforming growth factor, beta 2 ISO (MGI:894212|PMID:9217007) RGD PMID:9217007 MGI:894212 NCBI chr13:105,039,639...105,142,010
Ensembl chr13:105,039,853...105,141,030
JBrowse link
G Tgif1 TGFB-induced factor homeobox 1 ISO MGI:3698004 (MGI:3697552|PMID:17082251) RGD PMID:17082251 MGI:3697552 NCBI chr 9:119,181,079...119,190,698
Ensembl chr 9:119,181,083...119,190,698
JBrowse link
G Tmed2 transmembrane p24 trafficking protein 2 ISO MGI:4456438 (MGI:4453264|PMID:20178780) RGD PMID:20178780 MGI:4453264 NCBI chr12:37,471,259...37,480,344
Ensembl chr12:37,471,260...37,480,297
JBrowse link
G Traf6 TNF receptor associated factor 6 ISO (MGI:2181331|PMID:11007897) RGD PMID:11007897 MGI:2181331 NCBI chr 3:91,252,829...91,271,607
Ensembl chr 3:91,252,829...91,271,607
JBrowse link
G Trim71 tripartite motif containing 71 ISO MGI:4123844 (MGI:4356244|PMID:19098426) RGD PMID:19098426 MGI:4356244 NCBI chr 8:122,553,015...122,604,787
Ensembl chr 8:122,553,015...122,604,787
JBrowse link
G Tsc1 TSC complex subunit 1 ISO MGI:2183146 (MGI:2137425|PMID:11438694) RGD PMID:11438694 MGI:2137425 NCBI chr 3:7,219,955...7,269,063
Ensembl chr 3:7,237,192...7,265,145
JBrowse link
G Tsc2 TSC complex subunit 2 ISO MGI:1926345 (MGI:1333508|PMID:10096549) RGD PMID:10096549 MGI:1333508 NCBI chr10:13,962,006...13,996,684
Ensembl chr10:13,961,947...13,996,584
JBrowse link
G Tulp3 TUB like protein 3 ISO MGI:3664273 (MGI:3841513|PMID:19223390) RGD PMID:19223390 MGI:3841513 NCBI chr 4:161,636,084...161,677,807
Ensembl chr 4:161,637,892...161,658,519
JBrowse link
G Twist1 twist family bHLH transcription factor 1 ISO MGI:1857265 (MGI:72096|PMID:7729687) RGD PMID:7729687 MGI:72096 NCBI chr 6:53,401,241...53,403,235
Ensembl chr 6:53,401,109...53,403,214
JBrowse link
G Vangl2 VANGL planar cell polarity protein 2 ISO MGI:105056|MGI:107926|MGI:1100883|MGI:1349164|MGI:1857642|MGI:1918711|MGI:1923799|MGI:2139764|MGI:98958 (MGI:2153976|PMID:11709546), (MGI:2449213|PMID:12499390), (MGI:2676511|PMID:14512015), (MGI:3046397|PMID:15229603), (MGI:3703464|PMID:17229766), (MGI:3714704|PMID:17433286), (MGI:4438817|PMID:19966784), (MGI:4880797|PMID:21246654), (MGI:5498591|PMID:23760952) RGD PMID:11709546, PMID:12499390, PMID:14512015, PMID:15229603, PMID:17229766, PMID:17433286, PMID:19966784, PMID:21246654, PMID:23760952 MGI:2153976, MGI:2449213, MGI:2676511, MGI:3046397, MGI:3703464, MGI:3714704, MGI:4438817, MGI:4880797, MGI:5498591 NCBI chr13:90,379,203...90,405,627
Ensembl chr13:90,380,632...90,405,591
JBrowse link
G Vasp vasodilator-stimulated phosphoprotein IBA
ISO
PMID:21873635
MGI:108360 (MGI:3054149|PMID:15371503)
RGD PMID:15371503, PMID:21873635 MGI:3054149, RGD:13792537 NCBI chr 1:80,170,608...80,185,882
Ensembl chr 1:80,170,619...80,185,882
JBrowse link
G Wnt5a Wnt family member 5A ISO MGI:1298218|MGI:2135272 (MGI:3714704|PMID:17433286), (MGI:4413372|PMID:19795512) RGD PMID:17433286, PMID:19795512 MGI:3714704, MGI:4413372 NCBI chr16:4,469,451...4,490,271
Ensembl chr16:4,469,468...4,489,860
JBrowse link
G Zeb2 zinc finger E-box binding homeobox 2 ISO MGI:2387501 (MGI:3624924|PMID:16598713) RGD PMID:16598713 MGI:3624924 NCBI chr 3:29,857,289...29,985,932
Ensembl chr 3:29,862,473...29,996,865
JBrowse link
G Zic2 Zic family member 2 ISO MGI:1862004 (MGI:3056222|PMID:15384171) RGD PMID:15384171 MGI:3056222 NCBI chr15:108,908,366...108,913,812
Ensembl chr15:108,908,607...108,912,737
JBrowse link
G Zic5 Zic family member 5 ISO MGI:3052154 (MGI:3051968|PMID:15136147) RGD PMID:15136147 MGI:3051968 NCBI chr15:108,891,992...108,907,601
Ensembl chr15:108,891,992...108,898,703
JBrowse link
anterior neural tube closure term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 ISO MGI:5056374 (MGI:5050793|PMID:21515572) RGD PMID:21515572 MGI:5050793 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Folr1 folate receptor alpha ISO (MGI:3721767|PMID:17286298) RGD PMID:17286298 MGI:3721767 NCBI chr 1:166,934,457...166,945,864
Ensembl chr 1:166,934,460...166,943,592
JBrowse link
G Grhl2 grainyhead-like transcription factor 2 ISO MGI:5056365 (MGI:5050793|PMID:21515572) RGD PMID:21515572 MGI:5050793 NCBI chr 7:76,058,623...76,197,360
Ensembl chr 7:76,059,386...76,197,856
JBrowse link
G Specc1l sperm antigen with calponin homology and coiled-coil domains 1-like ISO MGI:4124253|MGI:4128888 (MGI:6101898|PMID:26787558) RGD PMID:26787558 MGI:6101898 NCBI chr20:14,287,470...14,393,879
Ensembl chr20:14,287,457...14,393,793
JBrowse link
anterior neuropore closure term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gatad2a GATA zinc finger domain containing 2A ISO (MGI:3762244|PMID:17565372) RGD PMID:17565372 MGI:3762244 NCBI chr16:21,177,793...21,267,768
Ensembl chr16:21,178,138...21,268,504
JBrowse link
G Tfap2a transcription factor AP-2 alpha ISO MGI:1888387 (MGI:80520|PMID:8622765) RGD PMID:8622765 MGI:80520 NCBI chr17:24,653,342...24,670,457
Ensembl chr17:24,654,902...24,670,457
JBrowse link
establishment of planar polarity involved in neural tube closure term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cthrc1 collagen triple helix repeat containing 1 ISO MGI:1915838 (MGI:3814781|PMID:18606138) RGD PMID:18606138 MGI:3814781 NCBI chr 7:77,966,722...77,977,004
Ensembl chr 7:77,966,722...77,977,004
JBrowse link
G Vangl2 VANGL planar cell polarity protein 2 ISO MGI:1857642 (MGI:3814781|PMID:18606138) RGD PMID:18606138 MGI:3814781 NCBI chr13:90,379,203...90,405,627
Ensembl chr13:90,380,632...90,405,591
JBrowse link
initiation of neural tube closure term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kdm2b lysine demethylase 2B ISO (MGI:4949568|PMID:21220025) RGD PMID:21220025 MGI:4949568 NCBI chr12:39,021,924...39,161,954
Ensembl chr12:39,078,119...39,161,956
JBrowse link
negative regulation of planar cell polarity pathway involved in neural tube closure term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lrp6 LDL receptor related protein 6 ISO MGI:98958 (MGI:4830282|PMID:19056682) RGD PMID:19056682 MGI:4830282 NCBI chr 4:168,194,054...168,323,962
Ensembl chr 4:168,194,927...168,323,751
JBrowse link
planar cell polarity pathway involved in neural tube closure term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Celsr1 cadherin, EGF LAG seven-pass G-type receptor 1 ISO MGI:1918711|MGI:2135272 (MGI:4830023|PMID:20704721) RGD PMID:20704721 MGI:4830023 NCBI chr 7:126,774,010...126,914,085
Ensembl chr 7:126,775,516...126,913,585
JBrowse link
G Dvl1 dishevelled segment polarity protein 1 IBA
ISO
PMID:21873635
MGI:106613 (MGI:3624185|PMID:16571627)
RGD PMID:16571627, PMID:21873635 MGI:3624185, RGD:13792537 NCBI chr 5:173,295,948...173,308,014
Ensembl chr 5:173,296,270...173,307,945
JBrowse link
G Dvl2 dishevelled segment polarity protein 2 IBA
ISO
PMID:21873635
MGI:2135272|MGI:2429760|MGI:94941 (MGI:3624185|PMID:16571627)
RGD PMID:16571627, PMID:21873635 MGI:3624185, RGD:13792537 NCBI chr10:56,609,810...56,619,269
Ensembl chr10:56,610,051...56,619,269
JBrowse link
G Dvl3 dishevelled segment polarity protein 3 IBA
ISO
PMID:21873635
MGI:2135272 (MGI:3821448|PMID:19008950)
RGD PMID:19008950, PMID:21873635 MGI:3821448, RGD:13792537 NCBI chr11:84,051,177...84,068,479
Ensembl chr11:84,051,078...84,068,302
JBrowse link
G Fzd1 frizzled class receptor 1 IEA
ISO
GO_REF:0000107
MGI:1888513|MGI:2135272 (MGI:4837757|PMID:20940229)
Ensembl
RGD
PMID:20940229 GO_REF:0000107, MGI:4837757 NCBI chr 4:26,470,864...26,475,262
Ensembl chr 4:26,470,864...26,475,262
JBrowse link
G Fzd2 frizzled class receptor 2 IEA
ISO
GO_REF:0000107
MGI:1196625|MGI:2135272 (MGI:4837757|PMID:20940229)
Ensembl
RGD
PMID:20940229 GO_REF:0000107, MGI:4837757 NCBI chr10:90,550,147...90,552,057
Ensembl chr10:90,550,147...90,552,057
JBrowse link
G Grhl3 grainyhead-like transcription factor 3 ISO MGI:2135272 (MGI:4819429|PMID:20643356) RGD PMID:20643356 MGI:4819429 NCBI chr 5:153,893,039...153,925,045
Ensembl chr 5:153,893,039...153,924,896
JBrowse link
G Ptk7 protein tyrosine kinase 7 ISO MGI:1100883|MGI:2135272 (MGI:4830023|PMID:20704721) RGD PMID:20704721 MGI:4830023 NCBI chr 9:16,662,588...16,729,888
Ensembl chr 9:16,702,460...16,729,030
JBrowse link
G Sfrp1 secreted frizzled-related protein 1 IEA
ISO
GO_REF:0000107
MGI:108078|MGI:1860298|MGI:2135272 (MGI:3793375|PMID:18257070)
Ensembl
RGD
PMID:18257070 GO_REF:0000107, MGI:3793375 NCBI chr16:73,372,007...73,410,777
Ensembl chr16:73,372,007...73,410,777
JBrowse link
G Sfrp2 secreted frizzled-related protein 2 ISO MGI:1860298|MGI:2135272|MGI:892014 (MGI:3793375|PMID:18257070) RGD PMID:18257070 MGI:3793375 NCBI chr 2:182,723,732...182,731,277
Ensembl chr 2:182,723,854...182,731,764
JBrowse link
G Sfrp5 secreted frizzled-related protein 5 ISO MGI:108078|MGI:2135272|MGI:892014 (MGI:3793375|PMID:18257070) RGD PMID:18257070 MGI:3793375 NCBI chr 1:261,442,108...261,446,570
Ensembl chr 1:261,442,108...261,446,570
JBrowse link
G Vangl2 VANGL planar cell polarity protein 2 ISO MGI:106613|MGI:108078|MGI:108100|MGI:1100883|MGI:1196625|MGI:1857642|MGI:1860298|MGI:1888513|MGI:1918711|MGI:2655333|MGI:892014 (MGI:3624185|PMID:16571627), (MGI:3793375|PMID:18257070), (MGI:3821448|PMID:19008950), (MGI:4819429|PMID:20643356), (MGI:4830023|PMID:20704721), (MGI:4837757|PMID:20940229) RGD PMID:16571627, PMID:18257070, PMID:19008950, PMID:20643356, PMID:20704721, PMID:20940229 MGI:3624185, MGI:3793375, MGI:3821448, MGI:4819429, MGI:4830023, MGI:4837757 NCBI chr13:90,379,203...90,405,627
Ensembl chr13:90,380,632...90,405,591
JBrowse link
G Wnt5a Wnt family member 5A IEA
ISO
GO_REF:0000107
MGI:1857617 (MGI:4830282|PMID:19056682)
Ensembl
RGD
PMID:19056682 GO_REF:0000107, MGI:4830282 NCBI chr16:4,469,451...4,490,271
Ensembl chr16:4,469,468...4,489,860
JBrowse link
regulation of establishment of planar polarity involved in neural tube closure term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sec24b SEC24 homolog B, COPII coat complex component ISO MGI:4440619|MGI:4440621 (MGI:4438817|PMID:19966784) RGD PMID:19966784 MGI:4438817 NCBI chr 2:230,286,886...230,356,887
Ensembl chr 2:230,287,296...230,356,919
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20020
    developmental process 6826
      anatomical structure formation involved in morphogenesis 1214
        tube formation 183
          tube closure 113
            neural tube closure 112
              anterior neural tube closure 4
              cell-cell adhesion involved in neural tube closure + 0
              establishment of planar polarity involved in neural tube closure + 16
              initiation of neural tube closure 1
              neuropore closure + 2
              planar cell polarity pathway involved in neural tube closure + 14
              progression of neural tube closure 0
Path 2
Term Annotations click to browse term
  biological_process 20020
    developmental process 6826
      anatomical structure development 6268
        tissue development 2099
          epithelium development 1262
            morphogenesis of an epithelium 586
              epithelial tube morphogenesis 399
                epithelial tube formation 167
                  embryonic epithelial tube formation 156
                    neural tube formation 134
                      primary neural tube formation 119
                        neural tube closure 112
                          anterior neural tube closure 4
                          cell-cell adhesion involved in neural tube closure + 0
                          establishment of planar polarity involved in neural tube closure + 16
                          initiation of neural tube closure 1
                          neuropore closure + 2
                          planar cell polarity pathway involved in neural tube closure + 14
                          progression of neural tube closure 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.