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ONTOLOGY REPORT - ANNOTATIONS


Term:cell killing
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Accession:GO:0001906 term browser browse the term
Definition:Any process in an organism that results in the killing of its own cells or those of another organism, including in some cases the death of the other organism. Killing here refers to the induction of death in one cell by another cell, not cell-autonomous death due to internal or other environmental conditions.
Synonyms:related_synonym: necrosis


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cell killing term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G C9 complement C9 JBrowse link NW_004955426 23,790,792 23,824,117 RGD:9068941
complement-dependent cytotoxicity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Rab27a RAB27A, member RAS oncogene family JBrowse link NW_004955409 588,725 621,874 RGD:9068941
cytolysis by host of symbiont cells term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G F2 coagulation factor II, thrombin JBrowse link NW_004955422 1,356,675 1,367,788 RGD:9068941
cytolysis in other organism term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hrg histidine rich glycoprotein JBrowse link NW_004955420 21,020,938 21,033,022 RGD:9068941
G Romo1 reactive oxygen species modulator 1 JBrowse link NW_004955422 25,757,558 25,760,054 RGD:9068941
cytolysis in other organism involved in symbiotic interaction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Krt6a keratin 6A JBrowse link NW_004955547 2,902,962 2,907,670 RGD:9068941
cytotoxic T cell degranulation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Rab27a RAB27A, member RAS oncogene family JBrowse link NW_004955409 588,725 621,874 RGD:9068941
killing by host of symbiont cells term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Camp cathelicidin antimicrobial peptide JBrowse link NW_004955420 24,911,920 24,914,698 RGD:9068941
G Gapdh glyceraldehyde-3-phosphate dehydrogenase JBrowse link NW_004955413 4,162,467 4,166,783 RGD:9068941
G Mbl2 mannose binding lectin 2 JBrowse link NW_004955425 7,704,371 7,708,951 RGD:9068941
killing of cells of other organism term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bpifa1 BPI fold containing family A member 1 JBrowse link NW_004955422 28,063,077 28,069,939 RGD:11554178
G Chga chromogranin A JBrowse link NW_004955438 15,092,267 15,104,321 RGD:9068941
G Cst11 cystatin 11 JBrowse link NW_004955415 30,445,556 30,453,439 RGD:9068941
G Dcd dermcidin JBrowse link NW_004955458 1,875,244 1,879,434 RGD:9068941
G Defb118 defensin beta 118 JBrowse link NW_004955422 29,554,310 29,560,660 RGD:9068941
G Defb128 defensin beta 128 JBrowse link NW_004955597 64,950 66,692 RGD:9068941
G Gapdh glyceraldehyde-3-phosphate dehydrogenase JBrowse link NW_004955413 4,162,467 4,166,783 RGD:9068941
G Hamp hepcidin antimicrobial peptide JBrowse link NW_004955468 4,576,080 4,577,591 RGD:9068941
G Hmgn2 high mobility group nucleosomal binding domain 2 JBrowse link NW_004955452 5,846,085 5,849,996 RGD:9068941
G LOC102004444 beta-defensin 1-like JBrowse link NW_004955403 53,643,328 53,644,361 RGD:11553838
G Ltf lactotransferrin JBrowse link NW_004955420 25,580,449 25,604,277 RGD:9068941
G Muc7 mucin 7, secreted JBrowse link NW_004955447 2,511,841 2,520,312 RGD:9068941
G Pglyrp1 peptidoglycan recognition protein 1 JBrowse link NW_004955574 424,046 427,675 RGD:9068941
G Pglyrp4 peptidoglycan recognition protein 4 JBrowse link NW_004955592 100,022 111,609 RGD:9068941
G Romo1 reactive oxygen species modulator 1 JBrowse link NW_004955422 25,757,558 25,760,054 RGD:9068941
G Rpl30 ribosomal protein L30 JBrowse link NW_004955417 13,764,814 13,767,698 RGD:9068941
G Rps19 ribosomal protein S19 JBrowse link NW_004955555 969,345 976,122 RGD:9068941
leukocyte mediated cytotoxicity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Stxbp2 syntaxin binding protein 2 JBrowse link NW_004955563 1,617,621 1,624,441 RGD:9068941
natural killer cell degranulation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Coro1a coronin 1A JBrowse link NW_004955493 6,815,148 6,820,295 RGD:9068941
G Rab27a RAB27A, member RAS oncogene family JBrowse link NW_004955409 588,725 621,874 RGD:9068941
G Unc13d unc-13 homolog D JBrowse link NW_004955506 6,407,073 6,423,406 RGD:9068941
G Vamp2 vesicle associated membrane protein 2 JBrowse link NW_004955467 8,793,296 8,796,771 RGD:9068941
G Vamp7 vesicle associated membrane protein 7 JBrowse link NW_004955594 20,496 72,648 RGD:9068941
natural killer cell mediated cytotoxicity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cebpg CCAAT enhancer binding protein gamma JBrowse link NW_004955468 3,137,106 3,141,733 RGD:9068941
G Il18 interleukin 18 JBrowse link NW_004955412 13,807,361 13,826,007 RGD:9068941
G LOC102005691 NKG2-D type II integral membrane protein JBrowse link NW_004955413 7,489,158 7,503,014 RGD:9068941
G Lyst lysosomal trafficking regulator JBrowse link NW_004955492 4,161,976 4,371,637 RGD:9068941
G Prdx1 peroxiredoxin 1 JBrowse link NW_004955464 12,761,390 12,773,413 RGD:9068941
G Ptpn6 protein tyrosine phosphatase non-receptor type 6 JBrowse link NW_004955413 4,525,954 4,547,177 RGD:9068941
G Raet1e retinoic acid early transcript 1E JBrowse link NW_004955439 11,413,978 11,420,902 RGD:9068941
G Slamf7 SLAM family member 7 JBrowse link NW_004955468 12,440,157 12,457,445 RGD:9068941
G Tubb tubulin beta class I JBrowse link NW_004955583 704,811 715,742 RGD:9068941
G Tubb4b tubulin beta 4B class IVb JBrowse link NW_004955513 5,237,050 5,239,370 RGD:9068941
negative regulation of antibody-dependent cellular cytotoxicity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fcgr2b Fc fragment of IgG receptor IIb JBrowse link NW_004955462 14,639,396 14,653,801 RGD:9068941
negative regulation of complement-dependent cytotoxicity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Il13 interleukin 13 JBrowse link NW_004955408 4,046,406 4,049,795 RGD:9068941
G Il4 interleukin 4 JBrowse link NW_004955408 4,058,052 4,065,999 RGD:9068941
negative regulation of cytolysis by symbiont of host cells term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Krt6a keratin 6A JBrowse link NW_004955547 2,902,962 2,907,670 RGD:9068941
negative regulation of cytotoxic T cell degranulation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ceacam1 carcinoembryonic antigen related cell adhesion molecule 1 JBrowse link NW_004955555 426,894 446,235 RGD:9068941
G Fcgr2b Fc fragment of IgG receptor IIb JBrowse link NW_004955462 14,639,396 14,653,801 RGD:9068941
negative regulation of natural killer cell mediated cytotoxicity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arrb2 arrestin beta 2 JBrowse link NW_004955467 10,109,985 10,118,687 RGD:9068941
G Clec12b C-type lectin domain family 12 member B JBrowse link NW_004955413 7,842,994 7,852,685 RGD:9068941
G Crk CRK proto-oncogene, adaptor protein JBrowse link NW_004955481 1,705,595 1,748,363 RGD:9068941
G Lgals9 galectin 9 JBrowse link NW_004955481 5,234,125 5,249,564 RGD:9068941
negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ceacam1 carcinoembryonic antigen related cell adhesion molecule 1 JBrowse link NW_004955555 426,894 446,235 RGD:9068941
G Havcr2 hepatitis A virus cellular receptor 2 JBrowse link NW_004955408 11,289,920 11,311,216 RGD:9068941
negative regulation of T cell mediated cytotoxicity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ceacam1 carcinoembryonic antigen related cell adhesion molecule 1 JBrowse link NW_004955555 426,894 446,235 RGD:9068941
G Il7r interleukin 7 receptor JBrowse link NW_004955426 20,785,896 20,818,512 RGD:9068941
G Ppp3cb protein phosphatase 3 catalytic subunit beta JBrowse link NW_004955437 18,323,852 18,377,815 RGD:9068941
G Ptprc protein tyrosine phosphatase receptor type C JBrowse link NW_004955406 35,005,577 35,127,395 RGD:9068941
neutrophil mediated killing of gram-negative bacterium term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G F2 coagulation factor II, thrombin JBrowse link NW_004955422 1,356,675 1,367,788 RGD:9068941
G Tusc2 tumor suppressor 2, mitochondrial calcium regulator JBrowse link NW_004955532 2,128,430 2,131,235 RGD:9068941
positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gapdh glyceraldehyde-3-phosphate dehydrogenase JBrowse link NW_004955413 4,162,467 4,166,783 RGD:9068941
positive regulation of apoptotic process by virus term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bad BCL2 associated agonist of cell death JBrowse link NW_004955422 20,795,585 20,809,039 RGD:9068941
G Bcl2l11 BCL2 like 11 JBrowse link NW_004955470 2,740,682 2,780,225 RGD:9068941
positive regulation of cytolysis in other organism term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pglyrp1 peptidoglycan recognition protein 1 JBrowse link NW_004955574 424,046 427,675 RGD:9068941
G Pglyrp4 peptidoglycan recognition protein 4 JBrowse link NW_004955592 100,022 111,609 RGD:9068941
positive regulation of killing of cells of other organism term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fcer2 Fc fragment of IgE receptor II JBrowse link NW_004955563 1,587,471 1,596,707 RGD:9068941
G Ifng interferon gamma JBrowse link NW_004955458 14,643,333 14,648,020 RGD:9068941
G Nos2 nitric oxide synthase 2 JBrowse link NW_004955481 5,197,957 5,232,406 RGD:9068941
G Prf1 perforin 1 JBrowse link NW_004955437 20,700,912 20,705,076 RGD:9068941
positive regulation of leukocyte mediated cytotoxicity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nos2 nitric oxide synthase 2 JBrowse link NW_004955481 5,197,957 5,232,406 RGD:9068941
positive regulation of microglial cell mediated cytotoxicity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Itgam integrin subunit alpha M JBrowse link NW_004955493 8,116,886 8,160,806 RGD:9068941
G Stap1 signal transducing adaptor family member 1 JBrowse link NW_004955447 5,292,708 5,345,214 RGD:9068941
G Tyrobp TYRO protein tyrosine kinase binding protein JBrowse link NW_004955468 2,673,657 2,677,633 RGD:9068941
positive regulation of natural killer cell degranulation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ap1g1 adaptor related protein complex 1 subunit gamma 1 JBrowse link NW_004955484 4,430,461 4,511,368 RGD:9068941
G Cd160 CD160 molecule JBrowse link NW_004955568 365,700 372,149 RGD:9068941
G Lamp1 lysosomal associated membrane protein 1 JBrowse link NW_004955404 557,090 573,532 RGD:9068941
positive regulation of natural killer cell mediated cytotoxicity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ap1g1 adaptor related protein complex 1 subunit gamma 1 JBrowse link NW_004955484 4,430,461 4,511,368 RGD:9068941
G Cadm1 cell adhesion molecule 1 JBrowse link NW_004955412 16,673,401 17,005,082 RGD:9068941
G Cd160 CD160 molecule JBrowse link NW_004955568 365,700 372,149 RGD:9068941
G Cd226 CD226 molecule JBrowse link NW_004955402 53,408,861 53,560,896 RGD:9068941
G Crtam cytotoxic and regulatory T cell molecule JBrowse link NW_004955412 23,676,171 23,706,250 RGD:9068941
G Il12a interleukin 12A JBrowse link NW_004955448 10,611,131 10,617,911 RGD:9068941
G Il18rap interleukin 18 receptor accessory protein JBrowse link NW_004955470 7,894,900 7,923,653 RGD:9068941
G Il21 interleukin 21 JBrowse link NW_004955428 18,057,096 18,065,492 RGD:9068941
G Lag3 lymphocyte activating 3 JBrowse link NW_004955413 4,379,529 4,385,456 RGD:9068941
G Lamp1 lysosomal associated membrane protein 1 JBrowse link NW_004955404 557,090 573,532 RGD:9068941
G LOC102005691 NKG2-D type II integral membrane protein JBrowse link NW_004955413 7,489,158 7,503,014 RGD:9068941
G Ncr3 natural cytotoxicity triggering receptor 3 JBrowse link NW_004955437 130,360 134,751 RGD:9068941
G Nectin2 nectin cell adhesion molecule 2 JBrowse link NW_004955555 1,959,702 1,985,679 RGD:9068941
G Raet1e retinoic acid early transcript 1E JBrowse link NW_004955439 11,413,978 11,420,902 RGD:9068941
G Rasgrp1 RAS guanyl releasing protein 1 JBrowse link NW_004955416 5,494,030 5,561,608 RGD:9068941
G Sh2d1a SH2 domain containing 1A JBrowse link NW_004955473 10,345,407 10,370,535 RGD:9068941
G Slamf6 SLAM family member 6 JBrowse link NW_004955468 12,233,629 12,264,502 RGD:9068941
G Stat5b signal transducer and activator of transcription 5B JBrowse link NW_004955451 16,253,645 16,295,337 RGD:9068941
G Vav1 vav guanine nucleotide exchange factor 1 JBrowse link NW_004955495 2,697,508 2,755,468 RGD:9068941
positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd226 CD226 molecule JBrowse link NW_004955402 53,408,861 53,560,896 RGD:9068941
G Crtam cytotoxic and regulatory T cell molecule JBrowse link NW_004955412 23,676,171 23,706,250 RGD:9068941
G Il12a interleukin 12A JBrowse link NW_004955448 10,611,131 10,617,911 RGD:9068941
G Il12b interleukin 12B JBrowse link NW_004955408 13,302,506 13,316,300 RGD:9068941
G LOC102005691 NKG2-D type II integral membrane protein JBrowse link NW_004955413 7,489,158 7,503,014 RGD:9068941
G Nectin2 nectin cell adhesion molecule 2 JBrowse link NW_004955555 1,959,702 1,985,679 RGD:9068941
positive regulation of neutrophil mediated killing of fungus term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arg1 arginase 1 JBrowse link NW_004955436 12,235,767 12,247,817 RGD:9068941
positive regulation of neutrophil mediated killing of gram-negative bacterium term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G F2rl1 F2R like trypsin receptor 1 JBrowse link NW_004955425 24,050,901 24,054,039 RGD:9068941
positive regulation of T cell mediated cytotoxicity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G B2m beta-2-microglobulin JBrowse link NW_004955416 11,205,503 11,211,325 RGD:9068941
G Fadd Fas associated via death domain JBrowse link NW_004955422 16,026,323 16,035,808 RGD:9068941
G Fam49b family with sequence similarity 49 member B JBrowse link NW_004955461 4,634,324 4,786,723 RGD:9068941
G Il12a interleukin 12A JBrowse link NW_004955448 10,611,131 10,617,911 RGD:9068941
G Il12b interleukin 12B JBrowse link NW_004955408 13,302,506 13,316,300 RGD:9068941
G Il12rb1 interleukin 12 receptor subunit beta 1 JBrowse link NW_004955524 3,276,932 3,299,617 RGD:9068941
G Il23a interleukin 23 subunit alpha JBrowse link NW_004955458 3,946,964 3,949,180 RGD:9068941
G Il23r interleukin 23 receptor JBrowse link NW_004955423 23,841,342 23,885,191 RGD:9068941
G P2rx7 purinergic receptor P2X 7 JBrowse link NW_004955482 7,048,674 7,087,525 RGD:9068941
G Ptprc protein tyrosine phosphatase receptor type C JBrowse link NW_004955406 35,005,577 35,127,395 RGD:9068941
G Stx7 syntaxin 7 JBrowse link NW_004955436 12,928,274 12,975,745 RGD:9068941
G Xcl1 X-C motif chemokine ligand 1 JBrowse link NW_004955462 8,594,416 8,598,101 RGD:9068941
regulation of complement-dependent cytotoxicity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Il10 interleukin 10 JBrowse link NW_004955406 42,307,789 42,312,255 RGD:9068941
G Il11 interleukin 11 JBrowse link NW_004955567 868,272 883,563 RGD:9068941
G Tgfb2 transforming growth factor beta 2 JBrowse link NW_004955406 174,949 249,248 RGD:9068941
regulation of killing of cells of other organism term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G P2rx7 purinergic receptor P2X 7 JBrowse link NW_004955482 7,048,674 7,087,525 RGD:9068941
regulation of leukocyte mediated cytotoxicity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Icam1 intercellular adhesion molecule 1 JBrowse link NW_004955495 1,561,464 1,573,282 RGD:9068941
regulation of natural killer cell mediated cytotoxicity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lep leptin JBrowse link NW_004955479 9,266,604 9,276,568 RGD:9068941
G Pik3r6 phosphoinositide-3-kinase regulatory subunit 6 JBrowse link NW_004955467 8,104,242 8,157,637 RGD:9068941
regulation of neutrophil mediated cytotoxicity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dnase1 deoxyribonuclease 1 JBrowse link NW_004955442 13,733,107 13,736,527 RGD:9068941
G Dnase1l3 deoxyribonuclease 1 like 3 JBrowse link NW_004955430 7,867,172 7,892,079 RGD:9068941
regulation of T cell mediated cytotoxicity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ager advanced glycosylation end-product specific receptor JBrowse link NW_004955437 645,482 648,607 RGD:9068941
G Ripk3 receptor interacting serine/threonine kinase 3 JBrowse link NW_004955409 35,961,604 35,965,477 RGD:9068941
susceptibility to natural killer cell mediated cytotoxicity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cadm1 cell adhesion molecule 1 JBrowse link NW_004955412 16,673,401 17,005,082 RGD:9068941
G Nectin2 nectin cell adhesion molecule 2 JBrowse link NW_004955555 1,959,702 1,985,679 RGD:9068941
G Raet1e retinoic acid early transcript 1E JBrowse link NW_004955439 11,413,978 11,420,902 RGD:9068941
susceptibility to T cell mediated cytotoxicity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nectin2 nectin cell adhesion molecule 2 JBrowse link NW_004955555 1,959,702 1,985,679 RGD:9068941
T cell mediated cytotoxicity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cadm1 cell adhesion molecule 1 JBrowse link NW_004955412 16,673,401 17,005,082 RGD:9068941
G Crtam cytotoxic and regulatory T cell molecule JBrowse link NW_004955412 23,676,171 23,706,250 RGD:9068941
G Ctsc cathepsin C JBrowse link NW_004955414 5,062,355 5,092,631 RGD:9068941
G Ctsh cathepsin H JBrowse link NW_004955533 39,237 54,881 RGD:9068941
G Emp2 epithelial membrane protein 2 JBrowse link NW_004955442 7,826,967 7,862,035 RGD:9068941
G Hprt1 hypoxanthine phosphoribosyltransferase 1 JBrowse link NW_004955473 462,940 510,006 RGD:9068941
G Prf1 perforin 1 JBrowse link NW_004955437 20,700,912 20,705,076 RGD:9068941
G Raet1e retinoic acid early transcript 1E JBrowse link NW_004955439 11,413,978 11,420,902 RGD:9068941
G Tsta3 tissue specific transplantation antigen P35B JBrowse link NW_004955454 2,313,172 2,317,829 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 14490
    cell killing 105
      complement-dependent cytotoxicity + 6
      killing of cells of other organism + 32
      leukocyte mediated cytotoxicity + 74
      negative regulation of cell killing + 13
      positive regulation of cell killing + 44
      regulation of cell killing + 66
paths to the root