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ONTOLOGY REPORT - ANNOTATIONS


Term:cell killing
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Accession:GO:0001906 term browser browse the term
Definition:Any process in an organism that results in the killing of its own cells or those of another organism, including in some cases the death of the other organism. Killing here refers to the induction of death in one cell by another cell, not cell-autonomous death due to internal or other environmental conditions.
Synonyms:related_synonym: necrosis


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cell killing term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G C9 complement C9 JBrowse link NW_004936518 2,947,956 2,994,892 RGD:9068941
complement-dependent cytotoxicity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Rab27a RAB27A, member RAS oncogene family JBrowse link NW_004936471 16,738,204 16,815,561 RGD:9068941
cytolysis by host of symbiont cells term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G F2 coagulation factor II, thrombin JBrowse link NW_004936562 2,371,725 2,388,617 RGD:9068941
cytolysis in other organism term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hrg histidine rich glycoprotein JBrowse link NW_004936578 3,285,986 3,295,876 RGD:9068941
G Reg3g regenerating family member 3 gamma JBrowse link NW_004936556 4,896,141 4,898,240 RGD:9068941
G Romo1 reactive oxygen species modulator 1 JBrowse link NW_004936561 5,134,068 5,135,734 RGD:9068941
cytolysis in other organism involved in symbiotic interaction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Krt6a keratin 6A JBrowse link NW_004936512 9,903,206 9,908,009 RGD:9068941
cytotoxic T cell degranulation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Rab27a RAB27A, member RAS oncogene family JBrowse link NW_004936471 16,738,204 16,815,561 RGD:9068941
killing by host of symbiont cells term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gapdh glyceraldehyde-3-phosphate dehydrogenase JBrowse link NW_004936709 1,243,149 1,247,782 RGD:9068941
killing of cells of other organism term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Chga chromogranin A JBrowse link NW_004936733 915,700 927,220 RGD:9068941
G Cst11 cystatin 11 JBrowse link NW_004936620 2,115,927 2,119,683 RGD:9068941
G Defb128 defensin beta 128 JBrowse link NW_004936485 18,238,442 18,240,625 RGD:9068941
G Defb132 defensin beta 132 JBrowse link NW_004936485 18,207,271 18,208,721 RGD:9068941
G Gapdh glyceraldehyde-3-phosphate dehydrogenase JBrowse link NW_004936709 1,243,149 1,247,782 RGD:9068941
G Hamp hepcidin antimicrobial peptide JBrowse link NW_004936570 1,009,344 1,010,654 RGD:9068941
G LOC101963795 60S ribosomal protein L30 JBrowse link NW_004936493 7,942,669 7,943,133 RGD:9068941
G Ltf lactotransferrin JBrowse link NW_004936596 344,287 373,788 RGD:9068941
G Lyz lysozyme JBrowse link NW_004936545 7,165,917 7,170,840 RGD:9068941
G Muc7 mucin 7, secreted JBrowse link NW_004936598 4,232,643 4,320,026 RGD:9068941
G Pglyrp1 peptidoglycan recognition protein 1 JBrowse link NW_004936706 2,317,137 2,320,993 RGD:9068941
G Romo1 reactive oxygen species modulator 1 JBrowse link NW_004936561 5,134,068 5,135,734 RGD:9068941
G Rps19 ribosomal protein S19 JBrowse link NW_004936706 568,443 575,973 RGD:9068941
leukocyte mediated cytotoxicity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Stxbp2 syntaxin binding protein 2 JBrowse link NW_004936588 4,688,221 4,696,075 RGD:9068941
natural killer cell degranulation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Coro1a coronin 1A JBrowse link NW_004936501 12,338,542 12,344,236 RGD:9068941
G Rab27a RAB27A, member RAS oncogene family JBrowse link NW_004936471 16,738,204 16,815,561 RGD:9068941
G Unc13d unc-13 homolog D JBrowse link NW_004936594 1,008,215 1,023,023 RGD:9068941
G Vamp2 vesicle associated membrane protein 2 JBrowse link NW_004936595 1,385,692 1,389,484 RGD:9068941
G Vamp7 vesicle associated membrane protein 7 JBrowse link NW_004936958 345,055 393,384 RGD:9068941
natural killer cell mediated cytotoxicity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cebpg CCAAT enhancer binding protein gamma JBrowse link NW_004936570 2,435,672 2,439,056 RGD:9068941
G Clec2a C-type lectin domain family 2 member A JBrowse link NW_004936902 583,850 586,981 RGD:9068941
G Il18 interleukin 18 JBrowse link NW_004936612 2,306,963 2,325,086 RGD:9068941
G LOC101976242 NKG2-D type II integral membrane protein JBrowse link NW_004936902 216,495 229,150 RGD:9068941
G Lyst lysosomal trafficking regulator JBrowse link NW_004936484 16,750,976 16,915,999 RGD:9068941
G Prdx1 peroxiredoxin 1 JBrowse link NW_004936474 26,641,776 26,653,291 RGD:9068941
G Ptpn6 protein tyrosine phosphatase non-receptor type 6 JBrowse link NW_004936709 864,206 884,630 RGD:9068941
G Tubb tubulin beta class I JBrowse link NW_004936837 380,880 384,752 RGD:9068941
G Tubb4b tubulin beta 4B class IVb JBrowse link NW_004936669 749,203 751,622 RGD:9068941
negative regulation of antibody-dependent cellular cytotoxicity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fcgr2b Fc fragment of IgG receptor IIb JBrowse link NW_004937131 80,014 96,114 RGD:9068941
negative regulation of complement-dependent cytotoxicity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Il13 interleukin 13 JBrowse link NW_004936647 2,529,933 2,532,503 RGD:9068941
G Il4 interleukin 4 JBrowse link NW_004936647 2,510,457 2,518,576 RGD:9068941
negative regulation of cytolysis by symbiont of host cells term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Krt6a keratin 6A JBrowse link NW_004936512 9,903,206 9,908,009 RGD:9068941
negative regulation of cytotoxic T cell degranulation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ceacam1 carcinoembryonic antigen related cell adhesion molecule 1 JBrowse link NW_004936706 37,480 53,306 RGD:9068941
G Fcgr2b Fc fragment of IgG receptor IIb JBrowse link NW_004937131 80,014 96,114 RGD:9068941
negative regulation of natural killer cell mediated cytotoxicity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arrb2 arrestin beta 2 JBrowse link NW_004936677 3,173,054 3,181,475 RGD:9068941
G Clec12b C-type lectin domain family 12 member B JBrowse link NW_004936902 520,825 528,181 RGD:9068941
G Crk CRK proto-oncogene, adaptor protein JBrowse link NW_004936538 7,581,453 7,609,543 RGD:9068941
G Lgals9 galectin 9 JBrowse link NW_004936538 4,034,467 4,050,240 RGD:9068941
negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ceacam1 carcinoembryonic antigen related cell adhesion molecule 1 JBrowse link NW_004936706 37,480 53,306 RGD:9068941
G Havcr2 hepatitis A virus cellular receptor 2 JBrowse link NW_004936515 6,001,324 6,015,407 RGD:9068941
negative regulation of T cell mediated cytotoxicity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ceacam1 carcinoembryonic antigen related cell adhesion molecule 1 JBrowse link NW_004936706 37,480 53,306 RGD:9068941
G Il7r interleukin 7 receptor JBrowse link NW_004936518 5,815,820 5,842,571 RGD:9068941
G Ppp3cb protein phosphatase 3 catalytic subunit beta JBrowse link NW_004936521 5,576,705 5,614,738 RGD:9068941
G Ptprc protein tyrosine phosphatase receptor type C JBrowse link NW_004936567 5,266,653 5,378,464 RGD:9068941
neutrophil mediated killing of gram-negative bacterium term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G F2 coagulation factor II, thrombin JBrowse link NW_004936562 2,371,725 2,388,617 RGD:9068941
G Tusc2 tumor suppressor 2, mitochondrial calcium regulator JBrowse link NW_004936529 1,853,092 1,856,027 RGD:9068941
positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gapdh glyceraldehyde-3-phosphate dehydrogenase JBrowse link NW_004936709 1,243,149 1,247,782 RGD:9068941
positive regulation of apoptotic process by virus term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bad BCL2 associated agonist of cell death JBrowse link NW_004936599 4,924,349 4,933,683 RGD:9068941
G Bcl2l11 BCL2 like 11 JBrowse link NW_004936783 15,493 50,959 RGD:9068941
positive regulation of cytolysis in other organism term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pglyrp1 peptidoglycan recognition protein 1 JBrowse link NW_004936706 2,317,137 2,320,993 RGD:9068941
positive regulation of killing of cells of other organism term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fcer2 Fc fragment of IgE receptor II JBrowse link NW_004936588 4,717,010 4,724,664 RGD:9068941
G Ifng interferon gamma JBrowse link NW_004936545 6,139,130 6,144,543 RGD:9068941
G Nos2 nitric oxide synthase 2 JBrowse link NW_004936538 4,052,277 4,097,051 RGD:9068941
G Prf1 perforin 1 JBrowse link NW_004936521 8,057,874 8,060,695 RGD:9068941
positive regulation of leukocyte mediated cytotoxicity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nos2 nitric oxide synthase 2 JBrowse link NW_004936538 4,052,277 4,097,051 RGD:9068941
positive regulation of microglial cell mediated cytotoxicity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Itgam integrin subunit alpha M JBrowse link NW_004936543 8,460,526 8,508,524 RGD:9068941
G Stap1 signal transducing adaptor family member 1 JBrowse link NW_004936582 877,241 908,697 RGD:9068941
G Tyrobp TYRO protein tyrosine kinase binding protein JBrowse link NW_004936570 457,993 460,735 RGD:9068941
positive regulation of natural killer cell degranulation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ap1g1 adaptor related protein complex 1 subunit gamma 1 JBrowse link NW_004936475 21,983,248 22,063,133 RGD:9068941
G Cd160 CD160 molecule JBrowse link NW_004936867 478,625 485,905 RGD:9068941
G Lamp1 lysosomal associated membrane protein 1 JBrowse link NW_004936472 377,359 389,121 RGD:9068941
positive regulation of natural killer cell mediated cytotoxicity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ap1g1 adaptor related protein complex 1 subunit gamma 1 JBrowse link NW_004936475 21,983,248 22,063,133 RGD:9068941
G Cadm1 cell adhesion molecule 1 JBrowse link NW_004936542 569,739 883,738 RGD:9068941
G Cd160 CD160 molecule JBrowse link NW_004936867 478,625 485,905 RGD:9068941
G Cd226 CD226 molecule JBrowse link NW_004937837 23,819 24,638 RGD:9068941
G Crtam cytotoxic and regulatory T cell molecule JBrowse link NW_004936542 7,402,879 7,411,510 RGD:9068941
G Il12a interleukin 12A JBrowse link NW_004936519 6,166,060 6,180,652 RGD:9068941
G Il18rap interleukin 18 receptor accessory protein JBrowse link NW_004936713 1,087,884 1,115,512 RGD:9068941
G Il21 interleukin 21 JBrowse link NW_004936662 1,689,879 1,696,883 RGD:9068941
G Lag3 lymphocyte activating 3 JBrowse link NW_004936709 1,041,519 1,048,630 RGD:9068941
G Lamp1 lysosomal associated membrane protein 1 JBrowse link NW_004936472 377,359 389,121 RGD:9068941
G LOC101976242 NKG2-D type II integral membrane protein JBrowse link NW_004936902 216,495 229,150 RGD:9068941
G Ncr3 natural cytotoxicity triggering receptor 3 JBrowse link NW_004936727 1,921,452 1,924,395 RGD:9068941
G Nectin2 nectin cell adhesion molecule 2 JBrowse link NW_004936706 1,470,910 1,498,986 RGD:9068941
G Rasgrp1 RAS guanyl releasing protein 1 JBrowse link NW_004936471 2,152,231 2,222,260 RGD:9068941
G Sh2d1a SH2 domain containing 1A JBrowse link NW_004936479 6,258,953 6,281,552 RGD:9068941
G Slamf6 SLAM family member 6 JBrowse link NW_004936740 155,268 165,536 RGD:9068941
G Stat5b signal transducer and activator of transcription 5B JBrowse link NW_004936490 17,022,268 17,043,751 RGD:9068941
G Vav1 vav guanine nucleotide exchange factor 1 JBrowse link NW_004936588 4,058,312 4,107,330 RGD:9068941
positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd226 CD226 molecule JBrowse link NW_004937837 23,819 24,638 RGD:9068941
G Crtam cytotoxic and regulatory T cell molecule JBrowse link NW_004936542 7,402,879 7,411,510 RGD:9068941
G Il12a interleukin 12A JBrowse link NW_004936519 6,166,060 6,180,652 RGD:9068941
G Il12b interleukin 12B JBrowse link NW_004936515 4,056,214 4,066,121 RGD:9068941
G LOC101976242 NKG2-D type II integral membrane protein JBrowse link NW_004936902 216,495 229,150 RGD:9068941
G Nectin2 nectin cell adhesion molecule 2 JBrowse link NW_004936706 1,470,910 1,498,986 RGD:9068941
positive regulation of neutrophil mediated killing of gram-negative bacterium term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G F2rl1 F2R like trypsin receptor 1 JBrowse link NW_004936549 142,281 153,575 RGD:9068941
positive regulation of T cell mediated cytotoxicity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G B2m beta-2-microglobulin JBrowse link NW_004936471 7,646,504 7,655,656 RGD:9068941
G Cd1e CD1e molecule JBrowse link NW_004936740 1,990,876 1,993,639 RGD:9068941
G Fadd Fas associated via death domain JBrowse link NW_004936599 633,501 639,412 RGD:9068941
G Fam49b family with sequence similarity 49 member B JBrowse link NW_004936470 18,665,898 18,803,864 RGD:9068941
G Il12a interleukin 12A JBrowse link NW_004936519 6,166,060 6,180,652 RGD:9068941
G Il12b interleukin 12B JBrowse link NW_004936515 4,056,214 4,066,121 RGD:9068941
G Il12rb1 interleukin 12 receptor subunit beta 1 JBrowse link NW_004936596 3,062,620 3,076,349 RGD:9068941
G Il23a interleukin 23 subunit alpha JBrowse link NW_004936646 743,630 745,998 RGD:9068941
G Il23r interleukin 23 receptor JBrowse link NW_004936591 4,365,598 4,425,053 RGD:9068941
G LOC101970885 lymphotactin JBrowse link NW_004936481 17,825,714 17,828,955 RGD:9068941
G P2rx7 purinergic receptor P2X 7 JBrowse link NW_004936558 3,106,819 3,149,689 RGD:9068941
G Ptprc protein tyrosine phosphatase receptor type C JBrowse link NW_004936567 5,266,653 5,378,464 RGD:9068941
G Stx7 syntaxin 7 JBrowse link NW_004936560 464,667 512,322 RGD:9068941
regulation of complement-dependent cytotoxicity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Il10 interleukin 10 JBrowse link NW_004936557 5,834,874 5,838,502 RGD:9068941
G Il11 interleukin 11 JBrowse link NW_004936886 617,531 620,661 RGD:9068941
G Tgfb2 transforming growth factor beta 2 JBrowse link NW_004936628 310,720 394,002 RGD:9068941
regulation of killing of cells of other organism term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G P2rx7 purinergic receptor P2X 7 JBrowse link NW_004936558 3,106,819 3,149,689 RGD:9068941
regulation of leukocyte mediated cytotoxicity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Icam1 intercellular adhesion molecule 1 JBrowse link NW_004936659 616,570 627,172 RGD:9068941
regulation of natural killer cell mediated cytotoxicity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lep leptin JBrowse link NW_004936479 15,394,966 15,411,334 RGD:9068941
G Pik3r6 phosphoinositide-3-kinase regulatory subunit 6 JBrowse link NW_004936595 1,953,372 1,983,765 RGD:9068941
regulation of neutrophil mediated cytotoxicity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dnase1 deoxyribonuclease 1 JBrowse link NW_004936694 704,948 715,846 RGD:9068941
G Dnase1l3 deoxyribonuclease 1 like 3 JBrowse link NW_004936473 8,430,235 8,495,170 RGD:9068941
regulation of T cell mediated cytotoxicity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ager advanced glycosylation end-product specific receptor JBrowse link NW_004936727 1,418,342 1,422,005 RGD:9068941
G Ripk3 receptor interacting serine/threonine kinase 3 JBrowse link NW_004936722 209,019 212,817 RGD:9068941
susceptibility to natural killer cell mediated cytotoxicity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cadm1 cell adhesion molecule 1 JBrowse link NW_004936542 569,739 883,738 RGD:9068941
G Nectin2 nectin cell adhesion molecule 2 JBrowse link NW_004936706 1,470,910 1,498,986 RGD:9068941
susceptibility to T cell mediated cytotoxicity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nectin2 nectin cell adhesion molecule 2 JBrowse link NW_004936706 1,470,910 1,498,986 RGD:9068941
T cell mediated cytotoxicity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cadm1 cell adhesion molecule 1 JBrowse link NW_004936542 569,739 883,738 RGD:9068941
G Crtam cytotoxic and regulatory T cell molecule JBrowse link NW_004936542 7,402,879 7,411,510 RGD:9068941
G Ctsc cathepsin C JBrowse link NW_004936736 1,201,343 1,240,311 RGD:9068941
G Ctsh cathepsin H JBrowse link NW_004936471 37,135,200 37,156,081 RGD:9068941
G Emp2 epithelial membrane protein 2 JBrowse link NW_004936530 8,854,266 8,862,127 RGD:9068941
G Hprt1 hypoxanthine phosphoribosyltransferase 1 JBrowse link NW_004936691 650,753 694,362 RGD:9068941
G Prf1 perforin 1 JBrowse link NW_004936521 8,057,874 8,060,695 RGD:9068941
G Tsta3 tissue specific transplantation antigen P35B JBrowse link NW_004936470 8,523,240 8,527,451 RGD:9068941

Term paths to the root
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Term Annotations click to browse term
  biological_process 14762
    cell killing 99
      complement-dependent cytotoxicity + 6
      killing of cells of other organism + 26
      leukocyte mediated cytotoxicity + 73
      negative regulation of cell killing + 13
      positive regulation of cell killing + 42
      regulation of cell killing + 64
paths to the root